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Development of a Safety Surveillance Plan for the Academic Medicine Sponsor Performing First-in-Human Cellular Therapy Clinical Trials: A Report from the Consortium for Pediatric Cellular Immunotherapy. Transplant Cell Ther. 2024 May; 30(5):475-487.
Adams C, Keller M, Michlitsch JG, Aguayo-Hiraldo P, Chen K, Hossain MZ, Davis A, Park JR, Verneris MR, Gardner RA. PMID: 38447751; PMCID: PMC11182654.
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Humans
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Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies. Pediatr Blood Cancer. 2023 06; 70(6):e30335.
Marinoff AE, Aaronson K, Agrawal AK, Braun BS, Golden C, Huang BJ, Michlitsch J, Southworth E, Thrall A, Vo KT, Stieglitz E. PMID: 37036306; PMCID: PMC10133180.
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3 Fields:
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Humans
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Abstract 1509: Longitudinal profiling of high-risk pediatric malignancies using a multiomics approach. Cancer Research. 2023 Apr 4; 83(7_Supplement):1509-1509.
Martell MH, Shah SA, Lee LA, Tanasa TB, Leung LS, Spillinger SA, Liu LH, Behroozfard BI, Dinh DP, Ventura VM, Hazard HF, Rangaswami RA, Spunt SS, Lacayo LN, Cooney CT, Michlitsch MJ, Agrawal AA, Breese BM, Sweet-Cordero SA. .
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A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma. Clin Cancer Res. 2022 09 15; 28(18):3950-3957.
Saulnier-Sholler G, Duda DG, Bergendahl G, Ebb D, Snuderl M, Laetsch TW, Michlitsch J, Hanson D, Isakoff MS, Bielamowicz K, Kraveka JM, Ferguson W, Carmeliet P, De Deene A, Gijsen L, Jain RK. PMID: 35833850; PMCID: PMC9481695.
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8 Fields:
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HumansCTClinical Trials
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Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy. Cold Spring Harb Mol Case Stud. 2022 Aug 04.
Smith SM, Lee A, Tong S, Leung S, Hongo H, Rivera J, Sweet-Cordero A, Michlitsch J, Stieglitz E. PMID: 35927023; PMCID: PMC9528968.
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2 Fields:
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Abstract 54: Integrative analysis of whole-genome and RNA sequencing in high-risk pediatric malignancies. Cancer Research. 2022 Jun 15; 82(12_Supplement):54-54.
Martell MH, Shah SA, Lee LA, Tanasa TB, Leung LS, Spillinger SA, Liu LH, Behroozfard BI, Dinh DP, Ventura VM, Hazard HF, Rangaswami RA, Spunt SS, Lacayo LN, Cooney CT, Michlitsch MJ, Agrawal AA, Breese BM, Sweet-Cordero SE. .
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Utilization of Thiopurine Metabolites and Allopurinol in Pediatric Acute Lymphoblastic Leukemia: Consideration for an Algorithmic Approach. J Pediatr Hematol Oncol. 2022 Mar 01; 44(2):e521-e525.
Mosher N, Torkildson J, Golden C, Raphael R, Beach B, Michlitsch J, Feusner JH, Agrawal AK. PMID: 34486570.
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1 Fields:
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Humans
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Abstract CT015: A phase 1 dose escalation study of TB-403 in pediatric relapsed or refractory medulloblastoma, neuroblastoma, Ewing sarcoma, or alveolar rhabdomyosarcoma. Cancer Research. 2021 Jul 1; 81(13_Supplement):ct015-ct015.
Sholler SG, Duda DD, Bergendahl BG, Ebb ED, Snuderl SM, Laetsch LT, Michlitsch MJ, Hanson HD, Isakoff IM, Bielamowicz BK, Kraveka KJ, Carmeliet CP, De Deene DA, Jain JR. .
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Nelarabine in Pediatric and Young Adult T-Cell Acute Lymphoblastic Leukemia-Clearly Beneficial? J Clin Oncol. 2021 02 20; 39(6):694.
Agrawal AK, Michlitsch J, Golden C, Hastings CA, Raphael R, Feusner JH. PMID: 33444071.
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2 Fields:
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HumansCells
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Association of image-defined risk factors with clinical features, histopathology, and outcomes in neuroblastoma. Cancer Med. 2021 04; 10(7):2232-2241.
Temple WC, Vo KT, Matthay KK, Balliu B, Coleman C, Michlitsch J, Phelps A, Behr S, Zapala MA. PMID: 33314708; PMCID: PMC7982630.
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16 Fields:
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Humans
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Abstract B20: Integrative analysis of whole-genome and RNA sequencing in high-risk pediatric malignancies. Cancer Research. 2020 Jul 15; 80(14_Supplement):b20-b20.
Shah SA, Breese BM, Lee LA, Martell MH, Tanasa TB, Leung LS, Spillingeer SA, Liu LH, Behroozfard BI, Dinh DP, Hazard HF, Cho CS, Rangaswami RA, Lacayo LN, Spunt SS, Cooney CT, Michlitsch MJ, Agarwaal AA, Sweet-Cordero SA. .
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Phase I trial of pazopanib in combination with irinotecan and temozolomide (PAZIT) for children and young adults with advanced sarcoma. Journal of Clinical Oncology. 2020 May 20; 38(15_suppl):10526-10526.
Vo VK, Michlitsch MJ, Shah SA, Reid RJ, Burhow BS, Graham GE, Hollinger HF, Zapala ZM, Long-Boyle LJ, Kim KM, Matthay MK, DuBois DS. .
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Potassium supplementation mitigates corticosteroid-induced neuropsychiatric effects in pediatric oncology patients. Pediatr Hematol Oncol. 2019 Oct; 36(7):445-450.
Pariury H, Willhoite J, Michlitsch J, Agrawal A. PMID: 31538841.
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HumansCTClinical Trials
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Langerhans Cell Histiocytosis of the Gastrointestinal Tract: Evidence for Risk Organ Status. J Pediatr. 2019 09; 212:66-72.e3.
Yoon HS, Lee JH, Michlitsch J, Garcia-Carega M, Jeng M. PMID: 31279573.
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1 Fields:
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Humans
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Abstract 3665: Integrative analysis of whole-genome and RNA sequencing in high-risk pediatric malignancies. Cancer Research. 2019 Jul 1; 79(13_Supplement):3665-3665.
Breese BM, Shah SA, Lee LA, Tanasa TB, Leung LS, Spillinger SA, Liu LH, Behroozfard BI, Dinh DP, Hazard HF, Rangaswami RA, Spunt SS, Lacayo LN, Cooney CT, Michlitsch MJ, Agrawal AA, Sweet-Cordero SE. .
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Vincristine-induced anemia in hereditary spherocytosis. Exp Biol Med (Maywood). 2019 07; 244(10):850-854.
Michlitsch J, Larkin S, Vichinsky E, Kuypers FA. PMID: 31161774; PMCID: PMC6643194.
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1 Fields:
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Humans
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Phase 1 multicenter trial to assess the maximum tolerated dose, safety, pharmacokinetics, and pharmacodynamics of pazopanib in combination with irinotecan and temozolomide (PAZIT) for children and young adults with advanced sarcoma. Journal of Clinical Oncology. 2018 May 20; 36(15_suppl):tps10576-tps10576.
Vo VK, Michlitsch MJ, Shah SA, Long-Boyle LJ, Kim KM, Gustafson GC, Sweet-Cordero SA, Matthay MK, DuBois DS. .
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Local control for vaginal botryoid rhabdomyosarcoma with pre-rectal transperineal surgical resection and autologous buccal graft vaginal replacement: A novel, minimally invasive, radiation-sparing approach. J Pediatr Surg. 2018 Jul; 53(7):1374-1380.
Michlitsch JG, Romao RLP, Gleason JM, Braga LH, Allen L, Gupta A, Lorenzo AJ. PMID: 29258699.
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2 Fields:
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Humans
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Cardiopulmonary Emergencies. Supportive Care in Pediatric Oncology. 2015 Jan 1; 59-69.
Michlitsch MJ. .
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Newborn screening for hemoglobinopathies in California. Pediatr Blood Cancer. 2009 Apr; 52(4):486-90.
Michlitsch J, Azimi M, Hoppe C, Walters MC, Lubin B, Lorey F, Vichinsky E. PMID: 19061217; PMCID: PMC4755934.
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PubMed Mentions:
48 Fields:
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HumansPHPublic Health
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Recent advances in bone marrow transplantation in hemoglobinopathies. Curr Mol Med. 2008 Nov; 8(7):675-89.
Michlitsch JG, Walters MC. PMID: 18991653.
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8 Fields:
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Humans
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High Frequency of Asthma, Sepsis and Acute Chest Syndrome in Children with Sickle Cell Disease and Pulmonary Hypertension. Blood. 2007 Nov 16; 110(11):3782-3782.
Morris MC, Hagar HW, Gardner GJ, Michlitsch MJ, Vichinsky VE. .
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Clinical differences between children and adults with pulmonary hypertension and sickle cell disease. Br J Haematol. 2008 Jan; 140(1):104-12.
Hagar RW, Michlitsch JG, Gardner J, Vichinsky EP, Morris CR. PMID: 17916102.
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23 Fields:
Translation:
Humans