Mark Walters, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
AddressBenioff Children's Oakland
747 52nd St.
Oakland CA 94609
Phone510-428-3374
ORCID ORCID Icon0000-0002-6515-4559 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, Berkeley, Berkeley, CAA.B.06/1981Genetics
    University of California, San Diego, La Jolla, CAM.D.06/1985Medicine
    University of Washington, Seattle, WA06/1988Pediatric Residency
    Fred Hutch/Univ of Washington, Seattle, WA06/1991Pediatric Hem/Onc/BMT fellowship
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    The over-arching goal of my research career has been to develop and expand curative therapies for hemoglobin disorders in particular and non-malignant hematopoietic disorders more broadly. I have focused on genome editing approaches most recently, which rely upon modification of autologous hematopoietic cells to elicit a curative effect. In collaboration with colleagues at UC Berkeley, BCHO and UCLA, we are pursuing genomic editing of the sickle mutation in hematopoietic stem cells using the CRSPR/Cas9 ribonucleoprotein system. I have a long track record of experience in cellular therapies for pediatric acquired and hereditary conditions and in bone marrow transplantation.

    Collapse Research 
    Collapse Research Activities and Funding
    Addressing safety issues by quantify large deletions and chromosomal rearrangements in HBB gene editing
    NIH OT2HL154977Apr 25, 2020 - Mar 31, 2022
    Role: Co-Investigator
    Clinical Microfluidic Assessment of Red Blood Cell Adhesion, Deformability, Cellular Hemoglobin Distribution, Cellular Density, and Blood Rheology for Curative Therapies in Sickle Cell Disease
    NIH OT2HL152643Sep 20, 2019 - Jun 30, 2021
    Role: Co-Investigator
    Curing Sickle Cell Disease with CRISPR-Cas9 genome editing
    NIH OT2HL151319Jun 12, 2019 - May 31, 2021
    Role: Principal Investigator
    Hematopoietic Stem Cell Transplantation for Young Adults with Sickle Cell Disease - Clinical Coordinating Center
    NIH U01HL128566Sep 1, 2015 - Jul 31, 2021
    Role: Co-Principal Investigator
    Hematopoietic Cell Therapy for Young Adults with Severe Sickle Cell Disease
    NIH R34HL108761Sep 1, 2011 - Apr 30, 2016
    Role: Co-Principal Investigator
    Northern California Consortium for Sickle Cell Disease
    NIH U10HL083704Apr 18, 2006 - Mar 31, 2011
    Role: Principal Investigator
    Induction of Stable Chimerism for Sickle Cell Anemia
    NIH U01HL068091Aug 25, 2001 - Jul 31, 2007
    Role: Principal Investigator
    MECHANISMS OF GLOBIN GENE SILENCING
    NIH R29HL060927Jul 10, 1998 - Jun 30, 2002
    Role: Principal Investigator
    MECHANISMS OF ERYTHROID GENE EXPRESSION
    NIH K08HL003098Jul 1, 1994 - Jun 30, 1999
    Role: Principal Investigator
    GLOBIN GENE REGULATION BY GATA-1 AND CHROMATIN
    NIH R01HL048790Aug 1, 1992 - Jun 30, 2001
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation. Blood Adv. 2021 Sep 28; 5(18):3668-3689. Kanter J, Liem RI, Bernaudin F, Bolaños-Meade J, Fitzhugh CD, Hankins JS, Murad MH, Panepinto JA, Rondelli D, Shenoy S, Wagner J, Walters MC, Woolford T, Meerpohl JJ, Tisdale J. PMID: 34581773.
      View in: PubMed   Mentions:    Fields:    
    2. Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2021: Looking Forward as the Network Celebrates its 20th Year. Transplant Cell Ther. 2021 Aug 27. Heslop HE, Stadtmauer EA, Levine JE, Ballen KK, Chen YB, DeZern AE, Eapen M, Hamadani M, Hamilton BK, Hari P, Jones RJ, Logan BR, Kean LS, Leifer ES, Locke FL, Maziarz RT, Nemecek ER, Pasquini M, Phelan R, Riches ML, Shaw BE, Walters MC, Foley A, Devine SM, Horowitz MM. PMID: 34461278.
      View in: PubMed   Mentions:
    3. Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation. Bone Marrow Transplant. 2021 Sep; 56(9):2221-2230. Friedman D, Dozor AJ, Milner J, D'Souza M, Talano JA, Moore TB, Shenoy S, Shi Q, Walters MC, Vichinsky E, Parsons SK, Braniecki S, Moorthy CR, Ayello J, Flower A, Morris E, Mahanti H, Fabricatore S, Klejmont L, van de Ven C, Baxter-Lowe LA, Cairo MS. PMID: 33958740.
      View in: PubMed   Mentions:    Fields:    
    4. Induction of Fetal Hemoglobin by Gene Therapy. N Engl J Med. 2021 01 21; 384(3):284-285. Walters MC. PMID: 33471981.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Risk score to predict event-free survival after hematopoietic cell transplant for sickle cell disease. Blood. 2020 07 30; 136(5):623-626. Brazauskas R, Scigliuolo GM, Wang HL, Cappelli B, Ruggeri A, Fitzhugh CD, Hankins JS, Kanter J, Meerpohl JJ, Panepinto JA, Rondelli D, Shenoy S, Walters MC, Wagner JE, Tisdale JF, Gluckman E, Eapen M. PMID: 32518950.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Sickle marrow: double, double toil and trouble. Blood. 2020 06 04; 135(23):2017-2018. Walters MC. PMID: 32497220.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Safety and feasibility of hematopoietic progenitor stem cell collection by mobilization with plerixafor followed by apheresis vs bone marrow harvest in patients with sickle cell disease in the multi-center HGB-206 trial. Am J Hematol. 2020 09; 95(9):E239-E242. Tisdale JF, Pierciey FJ, Bonner M, Thompson AA, Krishnamurti L, Mapara MY, Kwiatkowski JL, Shestopalov I, Ribeil JA, Huang W, Asmal M, Kanter J, Walters MC. PMID: 32401372.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    8. Myelodysplastic syndrome unrelated to lentiviral vector in a patient treated with gene therapy for sickle cell disease. Blood Adv. 2020 05 12; 4(9):2058-2063. Hsieh MM, Bonner M, Pierciey FJ, Uchida N, Rottman J, Demopoulos L, Schmidt M, Kanter J, Walters MC, Thompson AA, Asmal M, Tisdale JF. PMID: 32396618.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    9. End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Adv. 2019 12 10; 3(23):4002-4020. Farrell AT, Panepinto J, Desai AA, Kassim AA, Lebensburger J, Walters MC, Bauer DE, Blaylark RM, DiMichele DM, Gladwin MT, Green NS, Hassell K, Kato GJ, Klings ES, Kohn DB, Krishnamurti L, Little J, Makani J, Malik P, McGann PT, Minniti C, Morris CR, Odame I, Oneal PA, Setse R, Sharma P, Shenoy S. PMID: 31809537.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Related and unrelated donor transplantation for β-thalassemia major: results of an international survey. Blood Adv. 2019 09 10; 3(17):2562-2570. Li C, Mathews V, Kim S, George B, Hebert K, Jiang H, Li C, Zhu Y, Keesler DA, Boelens JJ, Dvorak CC, Agarwal R, Auletta JJ, Goyal RK, Hanna R, Kasow K, Shenoy S, Smith AR, Walters MC, Eapen M. PMID: 31471325.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    11. Effect of donor type and conditioning regimen intensity on allogeneic transplantation outcomes in patients with sickle cell disease: a retrospective multicentre, cohort study. Lancet Haematol. 2019 Nov; 6(11):e585-e596. Eapen M, Brazauskas R, Walters MC, Bernaudin F, Bo-Subait K, Fitzhugh CD, Hankins JS, Kanter J, Meerpohl JJ, Bolaños-Meade J, Panepinto JA, Rondelli D, Shenoy S, Williamson J, Woolford TL, Gluckman E, Wagner JE, Tisdale JF. PMID: 31495699.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    12. Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study. Am J Hematol. 2019 04; 94(4):446-454. Krishnamurti L, Neuberg DS, Sullivan KM, Kamani NR, Abraham A, Campigotto F, Zhang W, Dahdoul T, De Castro L, Parikh S, Bakshi N, Haight A, Hassell KL, Loving R, Rosenthal J, Smith SL, Smith W, Spearman M, Stevenson K, Wu CJ, Wiedl C, Waller EK, Walters MC. PMID: 30637784.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    13. CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells. PLoS One. 2019; 14(1):e0208237. Chung JE, Magis W, Vu J, Heo SJ, Wartiovaara K, Walters MC, Kurita R, Nakamura Y, Boffelli D, Martin DIK, Corn JE, DeWitt MA. PMID: 30645582.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    14. Promise of gene therapy to treat sickle cell disease. Expert Opin Biol Ther. 2018 11; 18(11):1123-1136. Romero Z, DeWitt M, Walters MC. PMID: 30324810.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    15. The safety and efficacy of clofarabine in combination with high-dose cytarabine and total body irradiation myeloablative conditioning and allogeneic stem cell transplantation in children, adolescents, and young adults (CAYA) with poor-risk acute leukemia. Bone Marrow Transplant. 2019 02; 54(2):226-235. Hochberg J, Zahler S, Geyer MB, Chen N, Krajewski J, Harrison L, Militano O, Ozkaynak MF, Cheerva AC, Talano J, Moore TB, Gillio AP, Walters MC, Baxter-Lowe LA, Hamby C, Cairo MS. PMID: 29899571.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    16. CIRM Alpha Stem Cell Clinics: Collaboratively Addressing Regenerative Medicine Challenges. Cell Stem Cell. 2018 06 01; 22(6):801-805. Jamieson CHM, Millan MT, Creasey AA, Lomax G, Donohoe ME, Walters MC, Abedi M, Bota DA, Zaia JA, Adams JS. PMID: 29859170.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia. N Engl J Med. 2018 04 19; 378(16):1479-1493. Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M. PMID: 29669226.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCellsCTClinical Trials
    18. Late Effects Screening Guidelines after Hematopoietic Cell Transplantation (HCT) for Hemoglobinopathy: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT. Biol Blood Marrow Transplant. 2018 07; 24(7):1313-1321. Shenoy S, Gaziev J, Angelucci E, King A, Bhatia M, Smith A, Bresters D, Haight AE, Duncan CN, de la Fuente J, Dietz AC, Baker KS, Pulsipher MA, Walters MC. PMID: 29653206.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    19. Unrelated Donor Transplantation in Children with Thalassemia using Reduced-Intensity Conditioning: The URTH Trial. Biol Blood Marrow Transplant. 2018 06; 24(6):1216-1222. Shenoy S, Walters MC, Ngwube A, Soni S, Jacobsohn D, Chaudhury S, Grimley M, Chan K, Haight A, Kasow KA, Parikh S, Andreansky M, Connelly J, Delgado D, Godder K, Hale G, Nieder M, Pulsipher MA, Trachtenberg F, Neufeld E, Kwiatkowski JL, Thompson AA. PMID: 29374585.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    20. The case for HLA-identical sibling hematopoietic stem cell transplantation in children with symptomatic sickle cell anemia. Blood Adv. 2017 Dec 12; 1(26):2563-2567. Fitzhugh CD, Walters MC. PMID: 29296908.
      View in: PubMed   Mentions: 4     Fields:    
    21. Relationship between Mixed Donor-Recipient Chimerism and Disease Recurrence after Hematopoietic Cell Transplantation for Sickle Cell Disease. Biol Blood Marrow Transplant. 2017 Dec; 23(12):2178-2183. Abraham A, Hsieh M, Eapen M, Fitzhugh C, Carreras J, Keesler D, Guilcher G, Kamani N, Walters MC, Boelens JJ, Tisdale J, Shenoy S, National Institutes of Health , Center for International Blood and Marrow Transplant Research . PMID: 28882446.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    22. Clinical risks and healthcare utilization of hematopoietic cell transplantation for sickle cell disease in the USA using merged databases. Haematologica. 2017 11; 102(11):1823-1832. Arnold SD, Brazauskas R, He N, Li Y, Aplenc R, Jin Z, Hall M, Atsuta Y, Dalal J, Hahn T, Khera N, Bonfim C, Majhail NS, Diaz MA, Freytes CO, Wood WA, Savani BN, Kamble RT, Parsons S, Ahmed I, Sullivan K, Beattie S, Dandoy C, Munker R, Marino S, Bitan M, Abdel-Azim H, Aljurf M, Olsson RF, Joshi S, Buchbinder D, Eckrich MJ, Hashmi S, Lazarus H, Marks DI, Steinberg A, Saad A, Gergis U, Krishnamurti L, Abraham A, Rangarajan HG, Walters M, Lipscomb J, Saber W, Satwani P. PMID: 28818869.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Dose-adapted post-transplant cyclophosphamide for HLA-haploidentical transplantation in Fanconi anemia. Bone Marrow Transplant. 2017 Apr; 52(4):570-573. Thakar MS, Bonfim C, Walters MC, Storb R, Pasquini R, Burroughs L, Sandmaier BM, Woolfrey A, Kiem HP. PMID: 28067886.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. Current Results and Future Research Priorities in Late Effects after Hematopoietic Stem Cell Transplantation for Children with Sickle Cell Disease and Thalassemia: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2017 Apr; 23(4):552-561. Shenoy S, Angelucci E, Arnold SD, Baker KS, Bhatia M, Bresters D, Dietz AC, De La Fuente J, Duncan C, Gaziev J, King AA, Pulsipher MA, Smith AR, Walters MC. PMID: 28065838.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    25. Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation. Blood. 2017 03 16; 129(11):1548-1556. Gluckman E, Cappelli B, Bernaudin F, Labopin M, Volt F, Carreras J, Pinto Simões B, Ferster A, Dupont S, de la Fuente J, Dalle JH, Zecca M, Walters MC, Krishnamurti L, Bhatia M, Leung K, Yanik G, Kurtzberg J, Dhedin N, Kuentz M, Michel G, Apperley J, Lutz P, Neven B, Bertrand Y, Vannier JP, Ayas M, Cavazzana M, Matthes-Martin S, Rocha V, Elayoubi H, Kenzey C, Bader P, Locatelli F, Ruggeri A, Eapen M, Eurocord, the Pediatric Working Party of the European Society for Blood and Marrow Transplantation, . PMID: 27965196.
      View in: PubMed   Mentions: 70     Fields:    Translation:Humans
    26. Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells. Sci Transl Med. 2016 10 12; 8(360):360ra134. DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo SJ, Mitros T, Muñoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DI, Corn JE. PMID: 27733558.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    27. The Second Pediatric Blood and Marrow Transplant Consortium International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Defining the Unique Late Effects of Children Undergoing Hematopoietic Cell Transplantation for Immune Deficiencies, Inherited Marrow Failure Disorders, and Hemoglobinopathies. Biol Blood Marrow Transplant. 2017 01; 23(1):24-29. Dietz AC, Duncan CN, Alter BP, Bresters D, Cowan MJ, Notarangelo L, Rosenberg PS, Shenoy S, Skinner R, Walters MC, Wagner J, Baker KS, Pulsipher MA. PMID: 27737772.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    28. A trial of unrelated donor marrow transplantation for children with severe sickle cell disease. Blood. 2016 11 24; 128(21):2561-2567. Shenoy S, Eapen M, Panepinto JA, Logan BR, Wu J, Abraham A, Brochstein J, Chaudhury S, Godder K, Haight AE, Kasow KA, Leung K, Andreansky M, Bhatia M, Dalal J, Haines H, Jaroscak J, Lazarus HM, Levine JE, Krishnamurti L, Margolis D, Megason GC, Yu LC, Pulsipher MA, Gersten I, DiFronzo N, Horowitz MM, Walters MC, Kamani N. PMID: 27625358.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCTClinical Trials
    29. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease. Biol Blood Marrow Transplant. 2016 Feb; 22(2):207-211. Walters MC, De Castro LM, Sullivan KM, Krishnamurti L, Kamani N, Bredeson C, Neuberg D, Hassell KL, Farnia S, Campbell A, Petersdorf E. PMID: 26500093.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    30. A booster shot to cure hemoglobinopathies. Blood. 2015 Sep 03; 126(10):1159-61. Walters MC, MacKenzie TC. PMID: 26337353.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    31. Update of hematopoietic cell transplantation for sickle cell disease. Curr Opin Hematol. 2015 May; 22(3):227-33. Walters MC. PMID: 25767957.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    32. In utero hematopoietic cell transplantation for hemoglobinopathies. Front Pharmacol. 2014; 5:278. Derderian SC, Jeanty C, Walters MC, Vichinsky E, MacKenzie TC. PMID: 25628564.
      View in: PubMed   Mentions:
    33. One-unit versus two-unit cord-blood transplantation for hematologic cancers. N Engl J Med. 2014 Oct 30; 371(18):1685-94. Wagner JE, Eapen M, Carter S, Wang Y, Schultz KR, Wall DA, Bunin N, Delaney C, Haut P, Margolis D, Peres E, Verneris MR, Walters M, Horowitz MM, Kurtzberg J, Blood and Marrow Transplant Clinical Trials Network . PMID: 25354103.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    34. Combined umbilical cord blood and bone marrow from HLA-identical sibling donors for hematopoietic stem cell transplantation in children with hemoglobinopathies. Pediatr Blood Cancer. 2014 Sep; 61(9):1690-4. Soni S, Boulad F, Cowan MJ, Scaradavou A, Dahake J, Edwards S, Walters MC. PMID: 24803091.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    35. Evaluation of the Spectra Optia apheresis system for mononuclear cell (MNC) collection in G-CSF mobilized and nonmobilized healthy donors: results of a multicenter study. J Clin Apher. 2014 Oct; 29(5):273-80. Karafin MS, Graminske S, Erickson P, Walters MC, Scott EP, Carter S, Padmanabhan A. PMID: 24677347.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    36. Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD). PLoS One. 2014; 9(2):e88868. Suh JH, Kanathezhath B, Shenvi S, Guo H, Zhou A, Tiwana A, Kuypers F, Ames BN, Walters MC. PMID: 24558439.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    37. β-globin gene transfer to human bone marrow for sickle cell disease. J Clin Invest. 2013 Jul 01. Romero Z, Urbinati F, Geiger S, Cooper AR, Wherley J, Kaufman ML, Hollis RP, de Assin RR, Senadheera S, Sahagian A, Jin X, Gellis A, Wang X, Gjertson D, Deoliveira S, Kempert P, Shupien S, Abdel-Azim H, Walters MC, Meiselman HJ, Wenby RB, Gruber T, Marder V, Coates TD, Kohn DB. PMID: 23863630.
      View in: PubMed   Mentions: 49     Fields:    
    38. Outcome of patients with hemoglobinopathies given either cord blood or bone marrow transplantation from an HLA-identical sibling. Blood. 2013 Aug 08; 122(6):1072-8. Locatelli F, Kabbara N, Ruggeri A, Ghavamzadeh A, Roberts I, Li CK, Bernaudin F, Vermylen C, Dalle JH, Stein J, Wynn R, Cordonnier C, Pinto F, Angelucci E, Socié G, Gluckman E, Walters MC, Rocha V, Eurocord and European Blood and Marrow Transplantation (EBMT) group . PMID: 23692854.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    39. Unrelated donor cord blood transplantation for children with severe sickle cell disease: results of one cohort from the phase II study from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). Biol Blood Marrow Transplant. 2012 Aug; 18(8):1265-72. Kamani NR, Walters MC, Carter S, Aquino V, Brochstein JA, Chaudhury S, Eapen M, Freed BM, Grimley M, Levine JE, Logan B, Moore T, Panepinto J, Parikh S, Pulsipher MA, Sande J, Schultz KR, Spellman S, Shenoy S. PMID: 22343376.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCTClinical Trials
    40. Hematopoietic cell transplantation for nonmalignant disorders. Biol Blood Marrow Transplant. 2012 Jan; 18(1 Suppl):S166-71. Tolar J, Mehta PA, Walters MC. PMID: 22226101.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    41. Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes. Exp Biol Med (Maywood). 2011 Apr 01; 236(4):492-504. Kanathezhath B, Mizokami M, Stanislaus S, Hounshell C, Neumayr L, Guo H, Hearst JE, Walters MC, Kuypers FA. PMID: 21454375.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    42. Umbilical cord blood transplantation for children with thalassemia and sickle cell disease. Biol Blood Marrow Transplant. 2011 Sep; 17(9):1375-82. Ruggeri A, Eapen M, Scaravadou A, Cairo MS, Bhatia M, Kurtzberg J, Wingard JR, Fasth A, Lo Nigro L, Ayas M, Purtill D, Boudjedir K, Chaves W, Walters MC, Wagner J, Gluckman E, Rocha V, Eurocord Registry , Center for International Blood and Marrow Transplant Research , New York Blood Center . PMID: 21277376.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    43. Umbilical cord blood transplantation for thalassemia major. Hematol Oncol Clin North Am. 2010 Dec; 24(6):1165-77. Kanathezhath B, Walters MC. PMID: 21075286.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. HLA-matched sibling bone marrow transplantation for β-thalassemia major. Blood. 2011 Feb 03; 117(5):1745-50. Sabloff M, Chandy M, Wang Z, Logan BR, Ghavamzadeh A, Li CK, Irfan SM, Bredeson CN, Cowan MJ, Gale RP, Hale GA, Horan J, Hongeng S, Eapen M, Walters MC. PMID: 21119108.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    45. Gene therapy and bone marrow transplantation for thalassemia: changing of the guard? Mol Ther. 2010 Sep; 18(9):1577. Walters MC. PMID: 20808320.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Stem-cell transplantation for sickle cell disease. N Engl J Med. 2010 Mar 11; 362(10):955-6; author reply 956. Walters MC, Sullivan KM. PMID: 20225347.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. Transplant outcomes in bone marrow failure syndromes and hemoglobinopathies. Semin Hematol. 2010 Jan; 47(1):37-45. MacMillan ML, Walters MC, Gluckman E. PMID: 20109610.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    48. Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease. Biol Blood Marrow Transplant. 2010 Feb; 16(2):263-72. Walters MC, Hardy K, Edwards S, Adamkiewicz T, Barkovich J, Bernaudin F, Buchanan GR, Bunin N, Dickerhoff R, Giller R, Haut PR, Horan J, Hsu LL, Kamani N, Levine JE, Margolis D, Ohene-Frempong K, Patience M, Redding-Lallinger R, Roberts IA, Rogers ZR, Sanders JE, Scott JP, Sullivan KM, Multicenter Study of Bone Marrow Transplantation for Sickle Cell Disease . PMID: 19822218.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    49. Translational stability for sickle gene therapy. Gene Ther. 2009 Aug; 16(8):943. Walters MC. PMID: 19554033.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    50. Human term placenta as a source of hematopoietic cells. Exp Biol Med (Maywood). 2009 Jul; 234(7):813-23. Serikov V, Hounshell C, Larkin S, Green W, Ikeda H, Walters MC, Kuypers FA. PMID: 19429852.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    51. Risk factors affecting outcome of second HLA-matched sibling donor transplantations for graft failure in severe acquired aplastic anemia. Biol Blood Marrow Transplant. 2009 May; 15(5):626-31. Horan JT, Carreras J, Tarima S, Camitta BM, Gale RP, Hale GA, Hinterberger W, Marsh J, Passweg JR, Walters MC, Eapen M. PMID: 19361755.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    52. Newborn screening for hemoglobinopathies in California. Pediatr Blood Cancer. 2009 Apr; 52(4):486-90. Michlitsch J, Azimi M, Hoppe C, Walters MC, Lubin B, Lorey F, Vichinsky E. PMID: 19061217.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    53. Recent advances in bone marrow transplantation in hemoglobinopathies. Curr Mol Med. 2008 Nov; 8(7):675-89. Michlitsch JG, Walters MC. PMID: 18991653.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    54. Transfusional iron burden and liver toxicity after bone marrow transplantation for acute myelogenous leukemia and hemoglobinopathies. Pediatr Blood Cancer. 2008 Feb; 50(2):319-24. Jastaniah W, Harmatz P, Pakbaz Z, Fischer R, Vichinsky E, Walters MC. PMID: 17557314.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    55. Hematopoietic cell transplantation for thalassemia and sickle cell disease: past, present and future. Bone Marrow Transplant. 2008 Jan; 41(2):109-17. Bhatia M, Walters MC. PMID: 18059330.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    56. Mixed haematopoietic chimerism for sickle cell disease prevents intravascular haemolysis. Br J Haematol. 2007 Nov; 139(3):504-7. Wu CJ, Gladwin M, Tisdale J, Hsieh M, Law T, Biernacki M, Rogers S, Wang X, Walters M, Zahrieh D, Antin JH, Ritz J, Krishnamurti L. PMID: 17910640.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    57. A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study. Blood. 2007 Dec 15; 110(13):4584-7. Frangoul H, Nemecek ER, Billheimer D, Pulsipher MA, Khan S, Woolfrey A, Manes B, Cole C, Walters MC, Ayas M, Ravindranath Y, Levine JE, Grupp SA. PMID: 17827386.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    58. Cord blood transplantation for sickle cell anemia: bust or boom? Pediatr Transplant. 2007 Sep; 11(6):582-3. Walters MC. PMID: 17663678.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    59. Matched-related donor transplantation for sickle cell disease: report from the Center for International Blood and Transplant Research. Br J Haematol. 2007 Jun; 137(5):479-85. Panepinto JA, Walters MC, Carreras J, Marsh J, Bredeson CN, Gale RP, Hale GA, Horan J, Hows JM, Klein JP, Pasquini R, Roberts I, Sullivan K, Eapen M, Ferster A, Non-Malignant Marrow Disorders Working Committee, Center for International Blood and Marrow Transpla . PMID: 17459050.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    60. Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia. Br J Haematol. 2007 Feb; 136(4):673-6. Eggleston B, Patience M, Edwards S, Adamkiewicz T, Buchanan GR, Davies SC, Dickerhoff R, Donfield S, Feig SA, Giller RH, Haight A, Horan J, Hsu LL, Kamani N, Lane P, Levine JE, Margolis D, Moore TB, Ohene-Frempong K, Redding-Lallinger R, Roberts IA, Rogers ZR, Sanders JE, Scott JP, Sleight B, Thompson AA, Sullivan KM, Walters MC, Multicenter Study of HCT for SCA . PMID: 17223910.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    61. Clinical hemoglobinopathies: iron, lungs and new blood. Curr Opin Hematol. 2006 Nov; 13(6):407-18. Morris CR, Singer ST, Walters MC. PMID: 17053452.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    62. The prevention and management of stroke in sickle cell anaemia. Expert Opin Biol Ther. 2006 Nov; 6(11):1087-98. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Qureshi N, Lubin B, Walters MC. PMID: 17049007.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    63. Hematopoietic stem cell transplantation for multiply transfused patients with sickle cell disease and thalassemia after low-dose total body irradiation, fludarabine, and rabbit anti-thymocyte globulin. Bone Marrow Transplant. 2005 Jan; 35(2):171-7. Horan JT, Liesveld JL, Fenton P, Blumberg N, Walters MC. PMID: 15531901.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCTClinical Trials
    64. Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia. Ann N Y Acad Sci. 2005; 1054:214-22. Kuypers FA, Watson G, Sage E, Walters MC, Hamrick J, Hearst JE. PMID: 16339668.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    65. Treatment of hepatitis C virus infection in thalassemia. Ann N Y Acad Sci. 2005; 1054:290-9. Butensky E, Pakbaz Z, Foote D, Walters MC, Vichinsky EP, Harmatz P. PMID: 16339677.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    66. Stem cell therapy for sickle cell disease: transplantation and gene therapy. Hematology Am Soc Hematol Educ Program. 2005; 66-73. Walters MC. PMID: 16304361.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    67. Outcomes of preimplantation genetic diagnosis therapy in treatment of beta-thalassemia: A retrospective analysis. Ann N Y Acad Sci. 2005; 1054:500-3. Qureshi N, Foote D, Walters MC, Singer ST, Quirolo K, Vichinsky EP. PMID: 16339706.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    68. Sibling donor cord blood transplantation for thalassemia major: Experience of the Sibling Donor Cord Blood Program. Ann N Y Acad Sci. 2005; 1054:206-13. Walters MC, Quirolo L, Trachtenberg ET, Edwards S, Hale L, Lee J, Morton-Wiley J, Quirolo K, Robertson S, Saba J, Lubin B. PMID: 16339667.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    69. Sickle cell anemia and hematopoietic cell transplantation: When is a pound of cure worth more than an ounce of prevention? Pediatr Transplant. 2004 Jun; 8 Suppl 5:33-8. Walters MC. PMID: 15125704.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    70. Haematopoietic cell transplantation in the treatment of sickle cell disease. Expert Opin Biol Ther. 2003 Dec; 3(8):1215-24. Atkins RC, Walters MC. PMID: 14640947.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    71. Results of minimally toxic nonmyeloablative transplantation in patients with sickle cell anemia and beta-thalassemia. Biol Blood Marrow Transplant. 2003 Aug; 9(8):519-28. Iannone R, Casella JF, Fuchs EJ, Chen AR, Jones RJ, Woolfrey A, Amylon M, Sullivan KM, Storb RF, Walters MC. PMID: 12931121.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCTClinical Trials
    72. Related umbilical cord blood transplantation in patients with thalassemia and sickle cell disease. Blood. 2003 Mar 15; 101(6):2137-43. Locatelli F, Rocha V, Reed W, Bernaudin F, Ertem M, Grafakos S, Brichard B, Li X, Nagler A, Giorgiani G, Haut PR, Brochstein JA, Nugent DJ, Blatt J, Woodard P, Kurtzberg J, Rubin CM, Miniero R, Lutz P, Raja T, Roberts I, Will AM, Yaniv I, Vermylen C, Tannoia N, Garnier F, Ionescu I, Walters MC, Lubin BH, Gluckman E, Eurocord Transplant Group . PMID: 12424197.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    73. Comprehensive banking of sibling donor cord blood for children with malignant and nonmalignant disease. Blood. 2003 Jan 01; 101(1):351-7. Reed W, Smith R, Dekovic F, Lee JY, Saba JD, Trachtenberg E, Epstein J, Haaz S, Walters MC, Lubin BH. PMID: 12393579.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    74. Novel therapeutic approaches in sickle cell disease. Hematology Am Soc Hematol Educ Program. 2002; 10-34. Walters MC, Nienhuis AW, Vichinsky E. PMID: 12446417.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    75. Sibling donor cord blood banking for children with sickle cell disease. Pediatr Pathol Mol Med. 2001 Mar-Apr; 20(2):167-74. Reed W, Walters M, Trachtenberg E, Smith R, Lubin BH. PMID: 12673840.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    76. Bone marrow transplantation in sickle cell anemia. Curr Opin Oncol. 2001 Mar; 13(2):85-90. Hoppe CC, Walters MC. PMID: 11224704.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    77. Stem cell transplantation for sickle cell disease: can we reduce the toxicity? Pediatr Pathol Mol Med. 2001 Jan-Feb; 20(1):73-86. Fixler J, Vichinsky E, Walters MC. PMID: 12673845.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    78. Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia. Biol Blood Marrow Transplant. 2001; 7(12):665-73. Walters MC, Patience M, Leisenring W, Rogers ZR, Aquino VM, Buchanan GR, Roberts IA, Yeager AM, Hsu L, Adamkiewicz T, Kurtzberg J, Vichinsky E, Storer B, Storb R, Sullivan KM, Multicenter Investigation of Bone Marrow Transplantation for Sickle Cell Disease . PMID: 11787529.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansCTClinical Trials
    79. Collection of sibling donor cord blood for children with thalassemia. J Pediatr Hematol Oncol. 2000 Nov-Dec; 22(6):602-4. Reed W, Walters M, Lubin BH. PMID: 11132238.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    80. Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Multicenter investigation of bone marrow transplantation for sickle cell disease. Blood. 2000 Mar 15; 95(6):1918-24. Walters MC, Storb R, Patience M, Leisenring W, Taylor T, Sanders JE, Buchanan GE, Rogers ZR, Dinndorf P, Davies SC, Roberts IA, Dickerhoff R, Yeager AM, Hsu L, Kurtzberg J, Ohene-Frempong K, Bunin N, Bernaudin F, Wong WY, Scott JP, Margolis D, Vichinsky E, Wall DA, Wayne AS, Pegelow C, Redding-Lallinger R, Wiley J, Klemperer M, Mentzer WC, Smith FO, Sullivan KM. PMID: 10706855.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCTClinical Trials
    81. Bone Marrow Transplantation for Non-Malignant Disease. Hematology Am Soc Hematol Educ Program. 2000; 319-338. Sullivan KM, Parkman R, Walters MC. PMID: 11701549.
      View in: PubMed   Mentions: 7     Fields:    
    82. Bone marrow transplantation for sickle cell disease: where do we go from here? J Pediatr Hematol Oncol. 1999 Nov-Dec; 21(6):467-74. Walters MC. PMID: 10598656.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    83. A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin. Cell. 1999 Oct 29; 99(3):259-69. Francastel C, Walters MC, Groudine M, Martin DI. PMID: 10555142.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    84. The chicken beta-globin 5'HS4 boundary element blocks enhancer-mediated suppression of silencing. Mol Cell Biol. 1999 May; 19(5):3714-26. Walters MC, Fiering S, Bouhassira EE, Scalzo D, Goeke S, Magis W, Garrick D, Whitelaw E, Martin DI. PMID: 10207095.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    85. Current and future preparative regimens for bone marrow transplantation in thalassemia. Ann N Y Acad Sci. 1998 Jun 30; 850:276-87. Storb R, Yu C, Deeg HJ, Georges G, Kiem HP, Mcsweeney PA, Nash RA, Sandmaier BM, Sullivan KM, Wagner JL, Walters MC. PMID: 9668549.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    86. Unrelated and HLA-nonidentical related donor marrow transplantation for thalassemia and leukemia. A combined report from the Seattle Marrow Transplant Team and the International Bone Marrow Transplant Registry. Ann N Y Acad Sci. 1998 Jun 30; 850:312-24. Sullivan KM, Anasetti C, Horowitz M, Rowlings PA, Petersdorf EW, Martin PJ, Clift RA, Walters MC, Gooley T, Sierra J, Anderson JE, Bjerke J, Siadak M, Flowers ME, Nash RA, Sanders JE, Appelbaum FR, Storb R, Hansen JA. PMID: 9668553.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    87. Collaborative multicenter investigation of marrow transplantation for sickle cell disease: current results and future directions. Biol Blood Marrow Transplant. 1997 Dec; 3(6):310-5. Walters MC, Patience M, Leisenring W, Rogers ZR, Dinndorf P, Davies SC, Roberts IA, Yeager A, Kurtzberg J, Bunin N, Scott JP, Wall DA, Wayne AS, Wiley J, Darbyshire PJ, Mentzer WC, Smith FO, Sullivan KM. PMID: 9502298.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    88. Bone marrow transplantation for sickle cell disease. N Engl J Med. 1996 Aug 08; 335(6):369-76. Walters MC, Patience M, Leisenring W, Eckman JR, Scott JP, Mentzer WC, Davies SC, Ohene-Frempong K, Bernaudin F, Matthews DC, Storb R, Sullivan KM. PMID: 8663884.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCTClinical Trials
    89. Barriers to bone marrow transplantation for sickle cell anemia. Biol Blood Marrow Transplant. 1996 May; 2(2):100-4. Walters MC, Patience M, Leisenring W, Eckman JR, Buchanan GR, Rogers ZR, Olivieri NE, Vichinsky E, Davies SC, Mentzer WC, Powars D, Scott JP, Bernaudin F, Ohene-Frempong K, Darbyshire PJ, Wayne A, Roberts IA, Dinndorf P, Brandalise S, Sanders JE, Matthews DC, Appelbaum FR, Storb R, Sullivan KM. PMID: 9118298.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    90. Transcriptional enhancers act in cis to suppress position-effect variegation. Genes Dev. 1996 Jan 15; 10(2):185-95. Walters MC, Magis W, Fiering S, Eidemiller J, Scalzo D, Groudine M, Martin DI. PMID: 8566752.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    91. Enhancers increase the probability but not the level of gene expression. Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15):7125-9. Walters MC, Fiering S, Eidemiller J, Magis W, Groudine M, Martin DI. PMID: 7624382.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    92. Neurologic complications after allogeneic marrow transplantation for sickle cell anemia. Blood. 1995 Feb 15; 85(4):879-84. Walters MC, Sullivan KM, Bernaudin F, Souillet G, Vannier JP, Johnson FL, Lenarsky C, Powars D, Bunin N, Ohene-Frempong K, et al. PMID: 7849310.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    93. Bone marrow transplantation for thalassemia. The USA experience. Am J Pediatr Hematol Oncol. 1994 Feb; 16(1):11-7. Walters MC, Sullivan KM, O'Reilly RJ, Boulad F, Brockstein J, Blume K, Amylon M, Johnson FL, Klemperer M, Graham-Pole J, et al. PMID: 8311166.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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