Elliot Stieglitz, MD

Title(s)Associate Professor, Pediatrics
SchoolSchool of Medicine
Address1450 Third St
San Francisco CA 94158
Phone415-502-2649
ORCID ORCID Icon0000-0001-7032-4623 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stony Brook MD2008School of Medicine
    New York Presbyterian - Weill Cornell2011Pediatric Residency
    University of California, San Francisco2014Pediatric Hematology Oncology Fellowship
    Collapse Awards and Honors
    V Foundation2019  - 2021Translational Research Award
    Pediatric Cancer Research Foundation2019  - 2020Research Award
    ASH/EHA2016  - 2016Translational Research Training in Hematology
    Alex's Lemonade Stand Foundation2015  - 2017Young Investigator Award
    American Cancer Society2016  - 2017Individual Research Award
    St. Baldrick's Foundation Fellowship2014  - 2016Fellow in Clinical Research

    Collapse Overview 
    Collapse Overview
    Juvenile myelomonocytic leukemia (JMML) is a blood cancer that affects young children and is often difficult to diagnose and treat. Currently available therapies cure only half of patients, with some children experiencing an aggressive disease course while a rare group get better with very little treatment. We have now shown that presence of secondary mutations at diagnosis predicts a poor outcome. We have also shown that DNA methylation profiling can identify patients most likely to experience favorable outcomes.

    We are currently running a clinical trial through the Children's Oncology Group for patients with relapsed and refractory JMML. This trial is testing the safety and efficacy of the oral MEK inhibitor, trametinib. This trial is based on extensive pre-clinical testing and a strong genomic rationale. This trial marks an important step towards more effectively treating patients with Ras driven leukemia using targeted agents.

    Our next trial will risk-stratify patients with newly diagnosed JMML to receive different therapies tailored to the risk of relapse predicted by both the number of mutations and DNA methylation signatures at diagnosis.

    Collapse Research 
    Collapse Research Activities and Funding
    Targeting SETBP1 in Myeloproliferative Disorders
    NIH K08HL135434Jan 1, 2017 - Dec 31, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia. Blood Adv. 2021 Sep 28; 5(18):3587-3591. Morales CE, Stieglitz E, Kogan SC, Loh ML, Braun BS. PMID: 34464969.
      View in: PubMed   Mentions:    Fields:    
    2. A simple and robust methylation test for risk stratification of patients with juvenile myelomonocytic leukemia. Blood Adv. 2021 Sep 27. Kitazawa H, Okuno Y, Muramatsu H, Aoki K, Murakami N, Wakamatsu M, Suzuki K, Narita K, Kataoka S, Ichikawa D, Hamada M, Taniguchi R, Kawashima N, Nishikawa E, Narita A, Nishio N, Hama A, Loh ML, Stieglitz E, Kojima S, Takahashi Y. PMID: 34580726.
      View in: PubMed   Mentions:    Fields:    
    3. JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β. Blood Adv. 2021 09 23. Yan Y, Dong L, Chen C, Bunting KD, Li Q, Stieglitz E, Loh ML, Qu CK. PMID: 34555844.
      View in: PubMed   Mentions:    Fields:    
    4. Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm. Blood Adv. 2021 Sep 22. Miltiadous O, Petrova-Drus K, Kaicker S, Mathew S, Kluk M, Geyer JT, Rodriguez-Sanchez MI, Bouvier N, Inghirami GG, Stieglitz E, Nafa K, Benayed R, Richardson M, Anderson W, Benhamida J, You D, Londono D, Kung AL, Prockop S, Roshal M, Zhang Y, Shukla NN. PMID: 34551074.
      View in: PubMed   Mentions:    Fields:    
    5. Juvenile myelomonocytic leukemia in the molecular era: a clinician's guide to diagnosis, risk-stratification, and treatment. Blood Adv. 2021 Sep 15. Wintering A, Dvorak CC, Stieglitz E, Loh ML. PMID: 34525182.
      View in: PubMed   Mentions:    Fields:    
    6. NUP98-NSD1 Driven MDS/MPN in Childhood Masquerading as JMML. J Pediatr Hematol Oncol. 2021 08 01; 43(6):e808-e811. Behnert A, Lee AG, Young EP, Breese MR, Leung SG, Behroozfard I, Maruffi M, Sweet-Cordero EA, Dvorak CC, Chu J, Stieglitz E. PMID: 32815876.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Exploring the genetic and epigenetic origins of juvenile myelomonocytic leukemia using newborn screening samples. Leukemia. 2021 Jun 28. Behnert A, Meyer J, Parsa JY, Hechmer A, Loh ML, Olshen A, de Smith AJ, Stieglitz E. PMID: 34183765.
      View in: PubMed   Mentions:    Fields:    
    8. Surface Proteomics Reveals CD72 as a Target for In Vitro-Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL. Cancer Discov. 2021 Aug; 11(8):2032-2049. Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera JM, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann BC, Satpathy AT, Manglik A, Stieglitz E, Wiita AP. PMID: 33727310.
      View in: PubMed   Mentions: 2     Fields:    
    9. Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Nat Commun. 2021 02 26; 12(1):1334. Kennedy AL, Myers KC, Bowman J, Gibson CJ, Camarda ND, Furutani E, Muscato GM, Klein RH, Ballotti K, Liu S, Harris CE, Galvin A, Malsch M, Dale D, Gansner JM, Nakano TA, Bertuch A, Vlachos A, Lipton JM, Castillo P, Connelly J, Churpek J, Edwards JR, Hijiya N, Ho RH, Hofmann I, Huang JN, Keel S, Lamble A, Lau BW, Norkin M, Stieglitz E, Stock W, Walkovich K, Boettcher S, Brendel C, Fleming MD, Davies SM, Weller EA, Bahl C, Carter SL, Shimamura A, Lindsley RC. PMID: 33637765.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium. Cancer Discov. 2021 Jun; 11(6):1424-1439. Pikman Y, Tasian SK, Sulis ML, Stevenson K, Blonquist TM, Apsel Winger B, Cooper TM, Pauly M, Maloney KW, Burke MJ, Brown PA, Gossai N, McNeer JL, Shukla NN, Cole PD, Kahn JM, Chen J, Barth MJ, Magee JA, Gennarini L, Adhav AA, Clinton CM, Ocasio-Martinez N, Gotti G, Li Y, Lin S, Imamovic A, Tognon CE, Patel T, Faust HL, Contreras CF, Cremer A, Cortopassi WA, Garrido Ruiz D, Jacobson MP, Dharia NV, Su A, Robichaud AL, Saur Conway A, Tarlock K, Stieglitz E, Place AE, Puissant A, Hunger SP, Kim AS, Lindeman NI, Gore L, Janeway KA, Silverman LB, Tyner JW, Harris MH, Loh ML, Stegmaier K. PMID: 33563661.
      View in: PubMed   Mentions:    Fields:    
    11. Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia. Haematologica. 2020 12 30; Online ahead of print. Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney KW, Narendran A, Oshrine B, Schultz KR, Sulis ML, Van Mater D, Tasian SK, Hofmann WK, Loh ML, Stieglitz E. PMID: 33375775.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Targeting the Ras pathway in pediatric hematologic malignancies. Curr Opin Pediatr. 2021 02 01; 33(1):49-58. Pikman Y, Stieglitz E. PMID: 33394740.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Genetic Alterations Precede DNA Methylation Changes in Juvenile Myelomonocytic Leukemia. Blood. 2020 Nov 5; 136(Supplement 1):19-20. Behnert BA, Meyer MJ, Parsa PJ, Hechmer HA, Loh LM, Olshen OA, de Smith dA, Stieglitz SE. .
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    14. Distinct Genetic Pathways Define Leukemia Predisposition Versus Adaptive Clonal Hematopoiesis in Shwachman-Diamond Syndrome. Blood. 2020 Nov 5; 136(Supplement 1):35-36. Kennedy KA, Myers MK, Bowman BJ, Gibson GC, Muscato MG, Klein KR, Ballotti BK, Camarda CN, Furutani FE, Harris HC, Liu LS, Galvin GA, Malsch MM, Dale DD, Gansner GJ, Nakano NT, Bertuch BA, Vlachos VA, Lipton LJ, Castillo CP, Connelly CJ, Edwards EJ, Hijiya HN, Ho HR, Hofmann HI, Huang HJ, Keel KS, Lamble LA, Lau LB, Walkovich WK, Norkin NM, Stock SW, Boettcher BS, Brendel BC, Stieglitz SE, Fleming FM, Davies DS, Weller WE, Bahl BC, Carter CS, Shimamura SA, Lindsley LR. .
      View in: Publisher Site   Mentions:
    15. International Consensus Definition of DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia. Clin Cancer Res. 2021 01 01; 27(1):158-168. Schönung M, Meyer J, Nöllke P, Olshen AB, Hartmann M, Murakami N, Wakamatsu M, Okuno Y, Plass C, Loh ML, Niemeyer CM, Muramatsu H, Flotho C, Stieglitz E, Lipka DB. PMID: 33139265.
      View in: PubMed   Mentions: 1     Fields:    
    16. Complete Response to PD-1 Inhibition in an Adolescent With Relapsed Clear Cell Adenocarcinoma of the Cervix Predicted by Neoepitope Burden and APOBEC Signature. JCO Precis Oncol. 2020; 4. Levinson A, Lee AG, Martell HJ, Breese MR, Zaloudek C, Van Ziffle J, Laguna B, Leung SG, Chen MD, Chen LM, Pfeil J, Ladwig NR, Shah AT, Behroozfard I, Rao AA, Salama SR, Sweet-Cordero EA, Stieglitz E. PMID: 33283136.
      View in: PubMed   Mentions:
    17. Clinical utilization of blinatumomab and inotuzumab immunotherapy in children with relapsed or refractory B-acute lymphoblastic leukemia. Pediatr Blood Cancer. 2021 01; 68(1):e28718. Contreras CF, Higham CS, Behnert A, Kim K, Stieglitz E, Tasian SK. PMID: 33098744.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Low toxicity and favorable overall survival in relapsed/refractory B-ALL following CAR T cells and CD34-selected T-cell depleted allogeneic hematopoietic cell transplant. Bone Marrow Transplant. 2020 11; 55(11):2160-2169. Fabrizio VA, Kernan NA, Boulad F, Cancio M, Allen J, Higman M, Margossian SP, Mauguen A, Prockop S, Scaradavou A, Shah N, Spitzer B, Stieglitz E, Yeager N, O'Reilly RJ, Brentjens RJ, Jan Boelens J, Curran KJ. PMID: 32390002.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    19. Precision cancer monitoring using a novel, fully integrated, microfluidic array partitioning digital PCR platform. Sci Rep. 2019 12 20; 9(1):19606. Dueck ME, Lin R, Zayac A, Gallagher S, Chao AK, Jiang L, Datwani SS, Hung P, Stieglitz E. PMID: 31862911.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2020 02; 67(2):e28079. Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC. PMID: 31724815.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation. Blood. 2019 Nov 13; 134(Supplement_1):1693-1693. Meyer MJ, Schönung SM, Flotho FC, Olshen OA, Hartmann HM, Plass PC, Okuno OY, Takahashi TY, Murakami MN, Wakamatsu WM, Loh LM, Niemeyer NC, Muramatsu MH, Lipka LD, Stieglitz SE. .
      View in: Publisher Site   Mentions:
    22. In Vitro-Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies. Blood. 2019 Nov 13; 134(Supplement_1):1337-1337. Nix NM, Lin LY, Geng GH, Marcoulis MM, Phojanakong PP, Wang WD, Steri SV, Whitman WJ, Bapat BS, Stieglitz SE, Deucher DA, White WK, Hann HB, Wiita WA. .
      View in: Publisher Site   Mentions:
    23. Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing. Leukemia. 2020 02; 34(2):662-666. Chao AK, Meyer JA, Lee AG, Hecht A, Tarver T, Van Ziffle J, Koegel AK, Golden C, Braun BS, Sweet-Cordero EA, Smith CC, Dvorak CC, Loh ML, Stieglitz E. PMID: 31511612.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    24. Molecular assessment of pretransplant chemotherapy in the treatment of juvenile myelomonocytic leukemia. Pediatr Blood Cancer. 2019 11; 66(11):e27948. Hecht A, Meyer J, Chehab FF, White KL, Magruder K, Dvorak CC, Loh ML, Stieglitz E. PMID: 31347788.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children. Genes Chromosomes Cancer. 2019 10; 58(10):723-730. de Smith AJ, Lavoie G, Walsh KM, Aujla S, Evans E, Hansen HM, Smirnov I, Kang AY, Zenker M, Ceremsak JJ, Stieglitz E, Muskens IS, Roberts W, McKean-Cowdin R, Metayer C, Roux PP, Wiemels JL, Wiemels JL. PMID: 31102422.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    26. Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome. Am J Hum Genet. 2019 06 06; 104(6):1223-1232. Capri Y, Flex E, Krumbach OHF, Carpentieri G, Cecchetti S, Lißewski C, Rezaei Adariani S, Schanze D, Brinkmann J, Piard J, Pantaleoni F, Lepri FR, Goh ES, Chong K, Stieglitz E, Meyer J, Kuechler A, Bramswig NC, Sacharow S, Strullu M, Vial Y, Vignal C, Kensah G, Cuturilo G, Kazemein Jasemi NS, Dvorsky R, Monaghan KG, Vincent LM, Cavé H, Verloes A, Ahmadian MR, Tartaglia M, Zenker M. PMID: 31130282.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    27. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nat Genet. 2019 04; 51(4):694-704. Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, Payne-Turner D, Tomizawa D, Kiyokawa N, Valentine M, Valentine V, Basso G, Locatelli F, Enemark EJ, Kham SKY, Yeoh AEJ, Ma X, Zhou X, Sioson E, Rusch M, Ries RE, Stieglitz E, Hunger SP, Wei AH, To LB, Lewis ID, D'Andrea RJ, Kile BT, Brown AL, Scott HS, Hahn CN, Marlton P, Pei D, Cheng C, Loh ML, Ebert BL, Meshinchi S, Haferlach T, Mullighan CG. PMID: 30926971.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    28. Phase I Study of the Selinexor in Relapsed/Refractory Childhood Acute Leukemia. Blood. 2018 Nov 29; 132(Supplement 1):1405-1405. Place PA, Blonquist BT, Stieglitz SE, Cooper CT, Gore GL, Aplenc AR, Loh LM, Pauly PM, Rau RR, Burke BM, Etchin EJ, Look LA, Sulis SM, Silverman SL. .
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    29. Germline GAB2 Mutations in Childhood Acute Lymphoblastic Leukemia. Blood. 2018 Nov 29; 132(Supplement 1):388-388. de Smith dA, Lavoie LG, Walsh WK, Aujla AS, Evans EE, Hansen HH, Smirnov SI, Kang KA, Zenker ZM, Ceremsak CJ, Stieglitz SE, McKean-Cowdin MR, Metayer MC, Roux RP, Wiemels WJ. .
      View in: Publisher Site   Mentions:
    30. DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia: An International Collaborative Analysis and Development of a Common Diagnostic Platform. Blood. 2018 Nov 29; 132(Supplement 1):3093-3093. Schoenung SM, Stieglitz SE, Muramatsu MH, Murakami MN, Hartmann HM, Wiesenfarth WM, Okuno OY, Olshen OA, Plass PC, Loh LM, Niemeyer NC, Flotho FC, Lipka LD. .
      View in: Publisher Site   Mentions:
    31. Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm. Leukemia. 2019 03; 33(3):671-685. Kong G, You X, Wen Z, Chang YI, Qian S, Ranheim EA, Letson C, Zhang X, Zhou Y, Liu Y, Rajagopalan A, Zhang J, Stieglitz E, Loh M, Hofmann I, Yang D, Zhong X, Padron E, Zhou L, Pear WS, Zhang J. PMID: 30206308.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. ABVD Without Radiation for Newly Diagnosed Pediatric and Young Adult Patients With Hodgkin Lymphoma: A Single Center Retrospective Analysis of 28 Consecutive Patients. J Pediatr Hematol Oncol. 2018 05; 40(4):290-294. Stieglitz E, Dinh T, Phelps AS, Pampaloni MH, Olshen AB, Robbins E. PMID: 29432308.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    33. Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study. Pediatr Blood Cancer. 2018 07; 65(7):e27034. Dvorak CC, Satwani P, Stieglitz E, Cairo MS, Dang H, Pei Q, Gao Y, Wall D, Mazor T, Olshen AB, Parker JS, Kahwash S, Hirsch B, Raimondi S, Patel N, Skeens M, Cooper T, Mehta PA, Grupp SA, Loh ML. PMID: 29528181.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    34. Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia. Nat Commun. 2017 12 19; 8(1):2127. Stieglitz E, Mazor T, Olshen AB, Geng H, Gelston LC, Akutagawa J, Lipka DB, Plass C, Flotho C, Chehab FF, Braun BS, Costello JF, Loh ML. PMID: 29259179.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    35. Dysregulation of the transcription factor runx1 in juvenile myelomonocytic leukemia. Experimental Hematology. 2017 Sep 1; 53:s51. Cantor CA, Dorantes-Costa DE, Huang HH, Garcia GS, Stieglitz SE, Loh LM, Yuan YG. .
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    36. Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML. Blood. 2017 07 27; 130(4):397-407. Yoshimi A, Balasis ME, Vedder A, Feldman K, Ma Y, Zhang H, Lee SC, Letson C, Niyongere S, Lu SX, Ball M, Taylor J, Zhang Q, Zhao Y, Youssef S, Chung YR, Zhang XJ, Durham BH, Yang W, List AF, Loh ML, Klimek V, Berger MF, Stieglitz E, Padron E, Abdel-Wahab O. PMID: 28576879.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    37. A Risk Stratified Treatment Algorithm for Patients with Juvenile Myelomonocytic Leukemia. . 2017 Mar 1; 14(2). Koegel KA, Stieglitz SE. .
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    38. International Interlaboratory Digital PCR Study Demonstrating High Reproducibility for the Measurement of a Rare Sequence Variant. Anal Chem. 2017 02 07; 89(3):1724-1733. Whale AS, Devonshire AS, Karlin-Neumann G, Regan J, Javier L, Cowen S, Fernandez-Gonzalez A, Jones GM, Redshaw N, Beck J, Berger AW, Combaret V, Dahl Kjersgaard N, Davis L, Fina F, Forshew T, Fredslund Andersen R, Galbiati S, González Hernández Á, Haynes CA, Janku F, Lacave R, Lee J, Mistry V, Pender A, Pradines A, Proudhon C, Saal LH, Stieglitz E, Ulrich B, Foy CA, Parkes H, Tzonev S, Huggett JF. PMID: 27935690.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    39. RUNX1 Is a Candidate Transcriptional Effector in Juvenile Myelomonocytic Leukemia. Blood. 2016 Dec 2; 128(22):2699-2699. Dorantes Acosta DE, Huang HH, Garcia GS, Stieglitz SE, Loh LM, Yuan YG, Cantor CA. .
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    40. Comprehensive Inflammatory Cytokine Profiling Identifies IL-8/CXCL8 As Elevated, Associated with Proliferative Features, and Independently Prognostic in Chronic Myelomonocytic Leukemia (CMML). Blood. 2016 Dec 2; 128(22):109-109. Niyongere NS, Lucas LN, Sansil SS, Cubitt CC, Balasis BM, Kroeger KJ, Zhang ZQ, Ceremsak CJ, Stieglitz SE, Zhao ZY, Ball BM, Komrokji KR, List LA, Santini SV, Solary SE, Padron PE. .
      View in: Publisher Site   Mentions:
    41. The Genomic Landscape of Childhood and Adult Acute Erythroid Leukemia. Blood. 2016 Dec 2; 128(22):39-39. Iacobucci II, Wen WJ, Meggendorfer MM, Carmichael CC, Choi CJ, Masih MK, Li LY, Payne PD, Tomizawa TD, Kiyokawa KN, Janke JL, Alexander AT, Pounds PS, Shi SL, Valentine VM, Basso BG, Locatelli LF, Kham Kow Yin KS, Yeoh Eng Juh YA, Rhonda RR, Stieglitz SE, Wei WA, Lewis LI, D'Andrea DR, Kile KB, Zhang ZJ, Loh LM, Meshinchi MS, Haferlach HT, Mullighan MC. .
      View in: Publisher Site   Mentions:
    42. Germline RRAS2 mutations are not associated with Noonan syndrome. J Med Genet. 2016 Nov; 53(11):728. Ceremsak JJ, Yu A, Esquivel E, Lissewski C, Zenker M, Loh ML, Stieglitz E. PMID: 27055474.
      View in: PubMed   Mentions: 2     Fields:    
    43. Pediatric MDS: GATA screen the germline. Blood. 2016 Mar 17; 127(11):1377-8. Stieglitz E, Loh ML. PMID: 26989184.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia. Nat Genet. 2016 Jan; 48(1):101. Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen SR, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo TA, Getz G, Gruber TA, Golub TR, Stegmaier K, Loh ML. PMID: 26711114.
      View in: PubMed   Mentions: 2     Fields:    
    45. Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2015 Apr; 62(4):629-36. Stieglitz E, Ward AF, Gerbing RB, Alonzo TA, Arceci RJ, Liu YL, Emanuel PD, Widemann BC, Cheng JW, Jayaprakash N, Balis FM, Castleberry RP, Bunin NJ, Loh ML, Cooper TM. PMID: 25704135.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    46. Subclonal Mutations in SETBP1 Predict Relapse in Juvenile Myelomonocytic Leukemia. Blood. 2014 Dec 6; 124(21):410-410. Stieglitz SE, Troup TC, Gelston GL, Chow CE, Yu YK, Akutagawa AJ, Taylor-Weiner TA, Liu LY, Emanuel EP, Braun BB, Gerbing GR, Alonzo AT, Loh LM. .
      View in: Publisher Site   Mentions:
    47. Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia. Blood. 2015 Jan 15; 125(3):516-24. Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo TA, Loh ML. PMID: 25395418.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    48. Mutations in GATA2 are rare in juvenile myelomonocytic leukemia. Blood. 2014 Feb 27; 123(9):1426-7. Stieglitz E, Liu YL, Emanuel PD, Castleberry RP, Cooper TM, Shannon KM, Loh ML. PMID: 24578498.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    49. Pulmonary coccidiomycosis masquerading as refractory metastatic Ewing sarcoma. J Pediatr Hematol Oncol. 2014 Jan; 36(1):e57-60. Stieglitz E, Hsiang MS, Simko JP, Hirose S, Goldsby RE. PMID: 23588326.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    50. Mutations In GATA2 Are Rare In Juvenile Myelomonocytic Leukemia. Blood. 2013 Nov 15; 122(21):1526-1526. Stieglitz SE, Liu LY, Emanuel EP, Castleberry CR, Cooper CT, Shannon SK, Loh LM. .
      View in: Publisher Site   Mentions:
    51. Genetic predispositions to childhood leukemia. Ther Adv Hematol. 2013 Aug; 4(4):270-90. Stieglitz E, Loh ML. PMID: 23926459.
      View in: PubMed   Mentions: