Karl Kumbier, PhD

Title(s)Data Scientist, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address1700 4th Street, #408
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts. Dev Cell. 2024 Aug 19; 59(16):2134-2142.e6. Kumbier K, Roth M, Li Z, Lazzari-Dean J, Waters C, Hammerlindl S, Rinaldi C, Huang P, Korobeynikov VA, New York Genome Center ALS Consortium, Phatnani H, Shneider N, Jacobson MP, Wu LF, Altschuler SJ. PMID: 38878774.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Epistasis regulates genetic control of cardiac hypertrophy. medRxiv. 2024 May 04. Wang Q, Tang TM, Youlton N, Weldy CS, Kenney AM, Ronen O, Weston Hughes J, Chin ET, Sutton SC, Agarwal A, Li X, Behr M, Kumbier K, Moravec CS, Wilson Tang WH, Margulies KB, Cappola TP, Butte AJ, Arnaout R, Brown JB, Priest JR, Parikh VN, Yu B, Ashley EA. PMID: 37987017; PMCID: PMC10659487.
      View in: PubMed   Mentions:
    3. Learning epistatic polygenic phenotypes with Boolean interactions. PLoS One. 2024; 19(4):e0298906. Behr M, Kumbier K, Cordova-Palomera A, Aguirre M, Ronen O, Ye C, Ashley E, Butte AJ, Arnaout R, Brown B, Priest J, Yu B. PMID: 38625909; PMCID: PMC11020961.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    4. Epistasis regulates genetic control of cardiac hypertrophy. Res Sq. 2023 Nov 20. Wang Q, Tang TM, Youlton N, Weldy CS, Kenney AM, Ronen O, Hughes JW, Chin ET, Sutton SC, Agarwal A, Li X, Behr M, Kumbier K, Moravec CS, Tang WHW, Margulies KB, Cappola TP, Butte AJ, Arnaout R, Brown JB, Priest JR, Parikh VN, Yu B, Ashley EA. PMID: 38045390; PMCID: PMC10690313.
      View in: PubMed   Mentions:
    5. Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity. Cell Rep. 2023 05 30; 42(5):112447. Rinaldi C, Waters CS, Li Z, Kumbier K, Rao L, Nichols RJ, Jacobson MP, Wu LF, Altschuler SJ. PMID: 37141099.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    6. Selection of Optimal Cell Lines for High-Content Phenotypic Screening. ACS Chem Biol. 2023 04 21; 18(4):679-685. Heinrich L, Kumbier K, Li L, Altschuler SJ, Wu LF. PMID: 36920184; PMCID: PMC10127200.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    7. Selection of optimal cell lines for high-content phenotypic screening. bioRxiv. 2023 Jan 12. Heinrich L, Kumbier K, Li L, Altschuler SP, Wu LF. PMID: 36711978; PMCID: PMC9882115.
      View in: PubMed   Mentions:
    8. A novel random forest approach to revealing interactions and controls on chlorophyll concentration and bacterial communities during coastal phytoplankton blooms. Sci Rep. 2021 10 07; 11(1):19944. Cheng Y, Bhoot VN, Kumbier K, Sison-Mangus MP, Brown JB, Kudela R, Newcomer ME. PMID: 34620921; PMCID: PMC8497483.
      View in: PubMed   Mentions: 1     Fields:    Translation:CellsPHPublic Health
    9. Veridical data science. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):3920-3929. Yu B, Kumbier K. PMID: 32054788; PMCID: PMC7049126.
      View in: PubMed   Mentions: 28     Fields:    
    10. Definitions, methods, and applications in interpretable machine learning. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22071-22080. Murdoch WJ, Singh C, Kumbier K, Abbasi-Asl R, Yu B. PMID: 31619572; PMCID: PMC6825274.
      View in: PubMed   Mentions: 217     Fields:    
    11. Iterative random forests to discover predictive and stable high-order interactions. Proc Natl Acad Sci U S A. 2018 02 20; 115(8):1943-1948. Basu S, Kumbier K, Brown JB, Yu B. PMID: 29351989; PMCID: PMC5828575.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
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