Kate Alfieri, PhD

Title(s)Director of Res Dev & Training, Anesthesia
SchoolSchool of Medicine
AddressRemote Location
Varies 00001
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco2019Diversity, Equity, and Inclusion Champion Training
    University of California, BerkeleyPh.D.2015Chemistry - Biophysical Chemistry
    Haverford CollegeB.S.2010Chemistry - Biochemistry
    Collapse Awards and Honors
    National Science Foundation 2010Graduate Research Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Kate Alfieri is the Director of Research Development and Training in the Department of Anesthesia and Perioperative Care. She is the primary scientific advisor to the Vice Chair for Research and develops, implements, and evaluates initiatives to address faculty and trainee research needs. Before joining UCSF, Kate was the Scientific Program Manager at the Stanford ChEM-H Institute, where she developed and managed interdisciplinary programs aimed to advance research and training at the interface of chemistry, engineering, and medicine.

    Kate received her B.S. in Chemistry with a concentration in Biochemistry from Haverford College and her Ph.D. in Chemistry, studying cell signaling at membrane interfaces, in the lab of Dr. Jay T. Groves at UC Berkeley. She is passionate about diversity in STEM, science communication and outreach, and mentorship in science.

    Collapse Research 
    Collapse Research Activities and Funding
    Comprehensive Anesthesia Research Training
    NIH/NIGMS T32GM008440Jul 1, 1995 - Jun 30, 2027
    Role: Collaborator, Administrator
    Description: The broad goal of our departmental T32 training grant program is to provide in-depth research training to talented individuals who are committed to pursuing basic, translational or clinical research focused on anesthesiology, critical care medicine and the surgical sciences. In 2021, the T32 training grant program received an Administrative Supplement for Curriculum or Training Activities to Enhance Wellness and Resiliency in the Training Environment (7/1/2021-6/30/2022).

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Membrane Association Transforms an Inert Anti-TCRβ Fab' Ligand into a Potent T Cell Receptor Agonist. Biophys J. 2020 06 16; 118(12):2879-2893. Lin JJ, O'Donoghue GP, Wilhelm KB, Coyle MP, Low-Nam ST, Fay NC, Alfieri KN, Groves JT. PMID: 32407684; PMCID: PMC7300389.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    2. Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events. Sci Signal. 2019 01 15; 12(564). Lin JJY, Low-Nam ST, Alfieri KN, McAffee DB, Fay NC, Groves JT. PMID: 30647147; PMCID: PMC6598675.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    3. Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination. Proc Natl Acad Sci U S A. 2017 11 14; 114(46):12190-12195. Pielak RM, O'Donoghue GP, Lin JJ, Alfieri KN, Fay NC, Low-Nam ST, Groves JT. PMID: 29087297; PMCID: PMC5699024.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    4. Using infrared spectroscopy of cyanylated cysteine to map the membrane binding structure and orientation of the hybrid antimicrobial peptide CM15. Biochemistry. 2011 Dec 27; 50(51):11097-108. Alfieri KN, Vienneau AR, Londergan CH. PMID: 22103476; PMCID: PMC3246368.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    5. Polyglutamine fibrils are formed using a simple designed beta-hairpin model. Proteins. 2010 Jun; 78(8):1971-9. Smith MH, Miles TF, Sheehan M, Alfieri KN, Kokona B, Fairman R. PMID: 20408173.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    6. Cyanylated Cysteine: A Covalently Attached Vibrational Probe of Protein-Lipid Contacts. J Phys Chem Lett. 2010 Mar 04; 1(5):850-855. McMahon HA, Alfieri KN, Clark KA, Londergan CH. PMID: 20228945; PMCID: PMC2836368.
      View in: PubMed   Mentions: 27     Fields: