Arthur Weiss, MD, PhD

Title(s)Professor Emeritus, Medicine
SchoolSchool of Medicine
AddressRemote Location
Varies 00001
PronounsDOM IT Supported
ORCID ORCID Icon0000-0002-2414-9024 Additional info
vCardDownload vCard
    Other Positions
    Title(s)Howard Hughes Investigator

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency Rheumatology
    Pritzker School of Medicine, University of Chicago, Chicago, ILMD, PhD1979Immunology
    University of California, San Francisco, CA2022Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    National Academy of Sciences2004Member
    UCSF2012Lifetime Achievement in Mentoring Award
    Institute of Medicine2004Member
    American Academy of Arts and Sciences2003Fellow
    UCSF1998Forty-first Faculty Research Lecturer
    European Molecular Biology Organization2017Associate Member
    American College of Rheumatology2016Ephraim P. Engleman Memorial Lecture
    University of Chicago2016Frank and Shirley Fitch Lecture
    American Association of Immunologists2012Lifetime Achievement Award
    American College of Rheumatology2004Distinguished Investigator Award
    American Association of Immunologists2001American Association of Immunologists-Huang Foundation Meritorious Career Award
    NIH, NIAID2016Merit Award
    Arthritis Foundation1997Lee C. Howley Prize
    American Association of Immunologists1993Junior Investigator Award
    Western Society for Clinical Investigation1990Young Investigator Award
    American College of Rheumatology1990Henry Kunkel Young Investigator Award
    UCSF2019Establishment of Arthur Weiss Lectureship in Rheumatology and Immunology
    U. Pittsburgh2019Eberly Lecture

    Collapse Overview 
    Collapse Overview
    Research Interest:

    The response of lymphocytes to antigen which initiates an antigen specific immune response also represents a unique opportunity to study how complex molecular interactions between cells can lead to developmental decisions, cell differentiation and proliferation. We are interested in understanding how receptors involved in antigen recognition can initiate signal transduction events that regulate cell responses in the immune system. We know that receptors involved in antigen recognition functionally interact with tyrosine kinases and phosphatases, enzymes that regulate protein phosphorylation, to induce signaling pathways that regulate cellular responses and gene expression. We are using genetically selective small molecule inhibitors of kinases together with phosphatase mutants to study how thresholds for the initiation of immune responses are set and how feedback circuits influence responses. We would like to understand how the tyrosine kinases and phosphatases in these pathways are regulated and how they control cellular responses in development, in normal immune responses and in autoimmune diseases such as lupus and rheumatoid arthritis.

    Collapse Research 
    Collapse Research Activities and Funding
    Academic Rheumatology and Clinical Immunology
    NIH T32AR079068Jun 1, 2021 - May 31, 2026
    Role: Principal Investigator
    FASEB SRC on Signal Transduction in the Immune System
    NIH R13AI131578May 1, 2017 - Apr 30, 2018
    Role: Principal Investigator
    The cell and molecular mechanisms underlying CD28 costimulation
    NIH R37AI114575Dec 8, 2015 - Nov 30, 2025
    Role: Principal Investigator
    The cell and molecular mechanisms underlying CD28 costimulation
    NIH/NIAID R01AI114575Dec 8, 2015 - Nov 30, 2020
    Role: Principal Investigator
    FASEB SRC on Signal Transduction in the Immune System
    NIH R13AI118149May 1, 2015 - Apr 30, 2016
    Role: Principal Investigator
    Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR
    NIH P01AI091580Jul 15, 2011 - Jun 30, 2021
    Role: Principal Investigator
    An allosteric inhibitor of ZAP-70 as a novel therapeutic for autoimmune disease
    NIH RC2AR058947Sep 25, 2009 - Aug 31, 2013
    Role: Principal Investigator
    Function of the RPTP CD148 in the Hematopoietic Lineage
    NIH R01AI066120Feb 15, 2006 - Jan 31, 2012
    Role: Principal Investigator
    Conference Proposal: Receptors and Signal Transduction
    NIH R13CA094912Jun 1, 2002 - May 31, 2003
    Role: Principal Investigator
    NIH P01AI045865Sep 30, 1999 - Aug 31, 2003
    Role: Co-Investigator
    NIH R01CA072531Feb 20, 1997 - Jan 31, 2006
    Role: Principal Investigator
    NIH R01GM044493Feb 1, 1992 - Jan 31, 1996
    Role: Principal Investigator
    NIH R01GM039553Feb 1, 1988 - Nov 30, 2001
    Role: Principal Investigator
    A Synchroton Radiation Structural Biology Resource
    NIH P41RR001209Mar 1, 1980 - Feb 28, 2015
    Role: Co-Investigator
    Medical Scientist Training Program
    NIH T32GM007618Jul 1, 1978 - Jun 30, 2021
    Role: Co-Principal Investigator
    Immune Tolerance and Autoimmunity
    NIH P01AI035297Jul 31, 2012
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments. Immunity. 2023 Dec 12; 56(12):2682-2698.e9. Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A. PMID: 38091950; PMCID: PMC10785950.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Peeking Into the Black Box of T Cell Receptor Signaling. Annu Rev Immunol. 2023 Oct 03. Weiss A. PMID: 37788477.
      View in: PubMed   Mentions:    Fields:    
    3. Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells. Proc Natl Acad Sci U S A. 2023 06 20; 120(25):e2300987120. Nguyen TTT, Lu W, Zhu WS, Ansel KM, Liang HE, Weiss A. PMID: 37307442; PMCID: PMC10288620.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P2 replenishment in response to TCR signaling during T cell development and survival. Nat Immunol. 2023 01; 24(1):136-147. Lu W, Helou YA, Shrinivas K, Liou J, Au-Yeung BB, Weiss A. PMID: 36581712; PMCID: PMC9810531.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    5. The phosphatidylinositol-transfer protein Nir3 modulates T cell development and function. The Journal of Immunology. 2022 May 1; 208(1_Supplement):166.12-166.12. Lu LW, Helou HY, Au-Yeung AB, Shrinivas SK, Liou LJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    6. Overcoming inhibitory constraints to TCR signaling by targeting the pH-sensitive phosphatase suppressor of T-cell receptor signaling 1 (STS1). The Journal of Immunology. 2022 May 1; 208(1_Supplement):166.14-166.14. Tsai TY, Badia BM, Kadlecek KT, Shah SN, Fong FL, Weiss WA. .
      View in: Publisher Site   Mentions:
    7. ZAP70, too little, too much can lead to autoimmunity. Immunol Rev. 2022 05; 307(1):145-160. Ashouri JF, Lo WL, Nguyen TTT, Shen L, Weiss A. PMID: 34923645; PMCID: PMC8986586.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    8. Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb. Elife. 2021 11 25; 10. Huang F, Nguyen TT, Echeverria I, Rakesh R, Cary DC, Paculova H, Sali A, Weiss A, Peterlin BM, Fujinaga K. PMID: 34821217; PMCID: PMC8648303.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway. Proc Natl Acad Sci U S A. 2021 10 26; 118(43). Lu W, Skrzypczynska KM, Weiss A. PMID: 34675079; PMCID: PMC8639343.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    10. Frank W. Fitch, M.D. Ph.D., 1929–2021. The Journal of Immunology. 2021 Jun 15; 206(12):2769-2772. Bluestone BJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    11. Cbl-b deficiency prevents functional but not phenotypic T cell anergy. J Exp Med. 2021 07 05; 218(7). Nguyen TTT, Wang ZE, Shen L, Schroeder A, Eckalbar W, Weiss A. PMID: 33974042; PMCID: PMC8117209.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    12. Adapting T Cell Receptor Ligand Discrimination Capability via LAT. Front Immunol. 2021; 12:673196. Lo WL, Weiss A. PMID: 33936119; PMCID: PMC8085316.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    13. A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands. Sci Signal. 2021 02 02; 14(668). Shen L, Matloubian M, Kadlecek TA, Weiss A. PMID: 33531381; PMCID: PMC8009134.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    14. Basal TCR signaling drives the functional heterogeneity of naïve CD4+ T cells. The Journal of Immunology. 2020 May 1; 204(1_Supplement):150.2-150.2. Au-Yeung AB, Weiss WA, Zinzow-Kramer ZW. .
      View in: Publisher Site   Mentions:
    15. The phosphatidinositol-transfer protein Nir3 is a modulator of T cell development. The Journal of Immunology. 2020 May 1; 204(1_Supplement):61.12-61.12. Helou HY, Au-Yeung AB, Weiss WA. .
      View in: Publisher Site   Mentions:
    16. CD4+ T cells are more sensitive to inhibition of TCR signaling under Th17 polarizing conditions. The Journal of Immunology. 2020 May 1; 204(1_Supplement):80.6-80.6. Zinzow-Kramer ZW, Weiss WA, Au-Yeung AB. .
      View in: Publisher Site   Mentions:
    17. Bruton's Tyrosine Kinase Membrane Dynamics and Signaling. Biophysical Journal. 2020 Feb 1; 118(3):560a-561a. Nocka NL, Chung CJ, Decker DA, Kadlecek KT, Weiss WA, Kuriyan KJ, Groves GJ. .
      View in: Publisher Site   Mentions:
    18. How the T Cell Signaling Network Processes Information to Discriminate between Self and Cognate Ligands. Biophysical Journal. 2020 Feb 1; 118(3):245a. Ganti GR, Lo LW, McAffee MD, Groves GJ, Weiss WA, Chakraborty CA. .
      View in: Publisher Site   Mentions:
    19. CD45 functions as a signaling gatekeeper in T cells. Sci Signal. 2019 10 22; 12(604). Courtney AH, Shvets AA, Lu W, Griffante G, Mollenauer M, Horkova V, Lo WL, Yu S, Stepanek O, Chakraborty AK, Weiss A. PMID: 31641081; PMCID: PMC6948007.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    20. Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nat Immunol. 2019 11; 20(11):1481-1493. Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. PMID: 31611699; PMCID: PMC6858552.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    21. Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18517-18527. Ashouri JF, Hsu LY, Yu S, Rychkov D, Chen Y, Cheng DA, Sirota M, Hansen E, Lattanza L, Zikherman J, Weiss A. PMID: 31455730; PMCID: PMC6744919.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    22. CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic. J Cell Biol. 2019 05 06; 218(5):1619-1633. Wang Y, Huynh W, Skokan TD, Lu W, Weiss A, Vale RD. PMID: 30814157; PMCID: PMC6504896.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    23. The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions. Blood. 2019 01 24; 133(4):331-343. Nagy Z, Vögtle T, Geer MJ, Mori J, Heising S, Di Nunzio G, Gareus R, Tarakhovsky A, Weiss A, Neel BG, Desanti GE, Mazharian A, Senis YA. PMID: 30429161; PMCID: PMC6484457.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    24. Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT. Nat Immunol. 2018 07; 19(7):733-741. Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A. PMID: 29915297; PMCID: PMC6202249.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    25. Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen. Elife. 2018 03 16; 7. Shah NH, Löbel M, Weiss A, Kuriyan J. PMID: 29547119; PMCID: PMC5889215.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    26. Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148. Blood. 2018 03 08; 131(10):1122-1144. Mori J, Nagy Z, Di Nunzio G, Smith CW, Geer MJ, Al Ghaithi R, van Geffen JP, Heising S, Boothman L, Tullemans BME, Correia JN, Tee L, Kuijpers MJE, Harrison P, Heemskerk JWM, Jarvis GE, Tarakhovsky A, Weiss A, Mazharian A, Senis YA. PMID: 29301754; PMCID: PMC5888341.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    27. IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells. Sci Signal. 2017 Dec 19; 10(510). Smith GA, Taunton J, Weiss A. PMID: 29259099; PMCID: PMC5741096.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    28. TCR Signaling: Mechanisms of Initiation and Propagation. Trends Biochem Sci. 2018 02; 43(2):108-123. Courtney AH, Lo WL, Weiss A. PMID: 29269020; PMCID: PMC5801066.
      View in: PubMed   Mentions: 227     Fields:    Translation:HumansAnimalsCells
    29. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45. Mol Cell. 2017 Aug 03; 67(3):498-511.e6. Courtney AH, Amacher JF, Kadlecek TA, Mollenauer MN, Au-Yeung BB, Kuriyan J, Weiss A. PMID: 28735895; PMCID: PMC5558854.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    30. Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness. J Exp Med. 2017 03 06; 214(3):833-849. Hsu LY, Cheng DA, Chen Y, Liang HE, Weiss A. PMID: 28159798; PMCID: PMC5339679.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    31. IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level. J Immunol. 2017 03 15; 198(6):2445-2456. Au-Yeung BB, Smith GA, Mueller JL, Heyn CS, Jaszczak RG, Weiss A, Zikherman J. PMID: 28159902; PMCID: PMC5340617.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    32. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. SLAS Discov. 2017 03; 22(3):324-331. Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. PMID: 27932698; PMCID: PMC5491343.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    33. Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells. J Immunol. 2017 01 15; 198(2):657-668. Ashouri JF, Weiss A. PMID: 27940659; PMCID: PMC5224971.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    34. Positive Regulation of Lyn Kinase by CD148 Is Required for B Cell Receptor Signaling in B1 but Not B2 B Cells. Immunity. 2016 12 20; 45(6):1232-1244. Skrzypczynska KM, Zhu JW, Weiss A. PMID: 27889108; PMCID: PMC5903562.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    35. Abstract A074: A Zap70-dependent negative feedback loop governs Lck activation by CD45. Other Topics. 2016 Nov 1; a074-a074. Courtney CA, Kadlecek KT, Au-Yeung AB, Weiss WA. .
      View in: Publisher Site   Mentions:
    36. An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. Elife. 2016 10 04; 5. Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. PMID: 27700984; PMCID: PMC5089863.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    37. Human LAT mutation results in immune deficiency and autoimmunity but also raises questions about signaling pathways. J Exp Med. 2016 06 27; 213(7):1114. Weiss A. PMID: 27353087; PMCID: PMC4925028.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    38. CD28 Costimulation: From Mechanism to Therapy. Immunity. 2016 05 17; 44(5):973-88. Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. PMID: 27192564; PMCID: PMC4932896.
      View in: PubMed   Mentions: 348     Fields:    Translation:HumansAnimalsCells
    39. Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Nat Chem Biol. 2016 May; 12(5):373-9. Smith GA, Uchida K, Weiss A, Taunton J. PMID: 27018889; PMCID: PMC4837022.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    40. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. J Exp Med. 2016 Feb 08; 213(2):155-65. Chan AY, Punwani D, Kadlecek TA, Cowan MJ, Olson JL, Mathes EF, Sunderam U, Fu SM, Srinivasan R, Kuriyan J, Brenner SE, Weiss A, Puck JM. PMID: 26783323; PMCID: PMC4749924.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    41. Abstract B042: Regulation of Lck activity by a cryptic phosphosite. Immune Regulation of T Cell Responses/ Evolving Concepts in Cancer Immunology. 2016 Jan 1; b042-b042. Courtney CA, Sjolin-Goodfellow SH, Ji JQ, Kadlecek KT, Salomon SA, Weiss WA. .
      View in: Publisher Site   Mentions:
    42. Targeted Activation of B Cell Autoimmunity Checkpoints in Acute Lymphoblastic Leukemia. Blood. 2015 Dec 3; 126(23):3716-3716. Chen CZ, Geng GH, Lowell LC, Weiss WA, Hunger HS, Melnick MA, Muschen MM. .
      View in: Publisher Site   Mentions:
    43. An extracatalytic function of CD45 in B cells is mediated by CD22. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):E6515-24. Coughlin S, Noviski M, Mueller JL, Chuwonpad A, Raschke WC, Weiss A, Zikherman J. PMID: 26561584; PMCID: PMC4664364.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    44. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife. 2015 Oct 30; 4. Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. PMID: 26517880; PMCID: PMC4626889.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    45. Small molecule inhibition of Csk alters affinity recognition by T cells. Elife. 2015 Aug 24; 4. Manz BN, Tan YX, Courtney AH, Rutaganira F, Palmer E, Shokat KM, Weiss A. PMID: 26302204; PMCID: PMC4568592.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    46. The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. Sci Signal. 2015 May 19; 8(377):ra49. Goodfellow HS, Frushicheva MP, Ji Q, Cheng DA, Kadlecek TA, Cantor AJ, Kuriyan J, Chakraborty AK, Salomon A, Weiss A. PMID: 25990959; PMCID: PMC4445242.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    47. Commentary: "The Role of T3 Surface Molecules in the Activation of Human Cells: A Two-Stimulus Requirement for IL-2 Production Reflects Events Occurring at a Pretranslational Level". Front Immunol. 2015; 6:163. Weiss A, Stobo JD. PMID: 25954271; PMCID: PMC4404948.
      View in: PubMed   Mentions: 2     Fields:    
    48. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015 May 21; 521(7552):357-61. Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M. PMID: 25799995; PMCID: PMC4441554.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    49. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13):E1594-603. Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T. PMID: 25829543; PMCID: PMC4386406.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    50. Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production. J Immunol. 2015 Apr 15; 194(8):3675-86. Mills RE, Lam VC, Tan A, Cresalia N, Oksenberg N, Zikherman J, Anderson M, Weiss A, Hermiston ML. PMID: 25769918; PMCID: PMC4503364.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    51. Erratum: Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Nature Immunology. 2015 Feb 1; 16(2):214-214. Au-Yeung AB, Melichar MH, Ross RJ, Cheng CD, Zikherman ZJ, Shokat SK, Robey RE, Weiss WA. .
      View in: Publisher Site   Mentions:
    52. Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation. J Clin Immunol. 2015 Feb; 35(2):135-46. Punwani D, Wang H, Chan AY, Cowan MJ, Mallott J, Sunderam U, Mollenauer M, Srinivasan R, Brenner SE, Mulder A, Claas FH, Weiss A, Puck JM. PMID: 25627829; PMCID: PMC4352191.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    53. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. Biochem J. 2015 Jan 01; 465(1):149-61. Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. PMID: 25287889; PMCID: PMC4410814.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    54. Insights into the initiation of TCR signaling. Nat Immunol. 2014 Sep; 15(9):798-807. Chakraborty AK, Weiss A. PMID: 25137454; PMCID: PMC5226627.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansCells
    55. A sharp T-cell antigen receptor signaling threshold for T-cell proliferation. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):E3679-88. Au-Yeung BB, Zikherman J, Mueller JL, Ashouri JF, Matloubian M, Cheng DA, Chen Y, Shokat KM, Weiss A. PMID: 25136127; PMCID: PMC4156735.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    56. Zap70 is essential for long-term survival of naive CD8 T cells. J Immunol. 2014 Sep 15; 193(6):2873-80. Schim van der Loeff I, Hsu LY, Saini M, Weiss A, Seddon B. PMID: 25092893; PMCID: PMC4167606.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    57. Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):E2550-8. Ross JO, Melichar HJ, Au-Yeung BB, Herzmark P, Weiss A, Robey EA. PMID: 24927565; PMCID: PMC4078834.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    58. Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Nat Immunol. 2014 Jul; 15(7):687-94. Au-Yeung BB, Melichar HJ, Ross JO, Cheng DA, Zikherman J, Shokat KM, Robey EA, Weiss A. PMID: 24908390; PMCID: PMC4095875.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    59. Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation. Elife. 2014 May 13; 3:e02270. Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. PMID: 24843022; PMCID: PMC4017645.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    60. Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210. Nat Immunol. 2014 Apr; 15(4):393-401. Wang H, Flach H, Onizawa M, Wei L, McManus MT, Weiss A. PMID: 24608041; PMCID: PMC3996831.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    61. Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL. Elife. 2014 Mar 04; 3:e01310. Jenkins MR, Stinchcombe JC, Au-Yeung BB, Asano Y, Ritter AT, Weiss A, Griffiths GM. PMID: 24596147; PMCID: PMC3936284.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    62. Protein kinase Cδ promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance. Mol Cell Biol. 2014 Apr; 34(8):1474-85. Limnander A, Zikherman J, Lau T, Leitges M, Weiss A, Roose JP. PMID: 24515435; PMCID: PMC3993585.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    63. Investigation of Novel Zap-70 Functionality in T Cell Signaling Pathways using Computational Modeling. Biophysical Journal. 2014 Jan 1; 106(2):376a-377a. Frushicheva FM, Weiss WA, Chakraborty CA. .
      View in: Publisher Site   Mentions:
    64. Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling. Nat Immunol. 2014 Feb; 15(2):186-94. Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. PMID: 24317039; PMCID: PMC3946925.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    65. Tony Pawson: Modular protein domains and the links to intracellular signaling. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):17604-5. Weiss A. PMID: 24135003; PMCID: PMC3816486.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    66. Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45. Cold Spring Harb Symp Quant Biol. 2013; 78:131-139. Tan YX, Zikherman J, Weiss A. PMID: 24100586; PMCID: PMC4039614.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    67. Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells. Immunity. 2013 Sep 19; 39(3):560-72. Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. PMID: 23993652; PMCID: PMC3804105.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    68. DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genet. 2013 Jul; 45(7):836-41. Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Madden PA, Mungall AJ, Tam A, Kamoh B, Cho S, Moore R, Hirst M, Marra MA, Costello JF, Wang T. PMID: 23708189; PMCID: PMC3695047.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    69. The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases. J Clin Invest. 2013 May; 123(5):2037-48. Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A. PMID: 23543053; PMCID: PMC3635736.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    70. Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. Mol Cell Biol. 2013 Jun; 33(11):2188-201. Yan Q, Barros T, Visperas PR, Deindl S, Kadlecek TA, Weiss A, Kuriyan J. PMID: 23530057; PMCID: PMC3648074.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    71. The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity. J Immunol. 2013 Mar 15; 190(6):2527-35. Zikherman J, Parameswaran R, Hermiston M, Weiss A. PMID: 23396948; PMCID: PMC3593789.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    72. Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases. Sci Signal. 2013 Jan 01; 6(256):ra1. Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A. PMID: 23281368; PMCID: PMC3742096.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    73. Science Signaling Podcast: 1 January 2013. Science Signaling. 2013 Jan 1; 6(256). Weiss WA, Das DJ, VanHook VA. .
      View in: Publisher Site   Mentions:
    74. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J Clin Invest. 2012 Dec; 122(12):4592-605. Charles JF, Hsu LY, Niemi EC, Weiss A, Aliprantis AO, Nakamura MC. PMID: 23114597; PMCID: PMC3533532.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    75. Endogenous antigen tunes the responsiveness of naive B cells but not T cells. Nature. 2012 Sep 06; 489(7414):160-4. Zikherman J, Parameswaran R, Weiss A. PMID: 22902503; PMCID: PMC3438375.
      View in: PubMed   Mentions: 179     Fields:    Translation:AnimalsCells
    76. Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature. 2012 Aug 16; 488(7411):384-8. Wei P, Wong WW, Park JS, Corcoran EE, Peisajovich SG, Onuffer JJ, Weiss A, Lim WA. PMID: 22820255; PMCID: PMC3422413.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    77. A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012 Apr 19; 1(4):385-91. Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, de Jong PJ, Bluestone JA, Srivastava D, McManus MT. PMID: 22570807; PMCID: PMC3345170.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    78. The membrane environment can promote or suppress bistability in cell signaling networks. J Phys Chem B. 2012 Mar 22; 116(11):3630-40. Abel SM, Roose JP, Groves JT, Weiss A, Chakraborty AK. PMID: 22332778; PMCID: PMC3321252.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    79. Lymphocyte signaling: a Tuscan affair. Nat Immunol. 2011 Dec 16; 13(1):3-6. Baldari CT, Acuto O, Batista F, Koretzky G, Weiss A. PMID: 22179269.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    80. Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):E3-12. Zikherman J, Doan K, Parameswaran R, Raschke W, Weiss A. PMID: 22135465; PMCID: PMC3252956.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    81. Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease. J Clin Invest. 2011 Dec; 121(12):4618-21. Zikherman J, Weiss A. PMID: 22080861; PMCID: PMC3226009.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    82. Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus. Immunity. 2011 Nov 23; 35(5):757-69. Zhu JW, Doan K, Park J, Chau AH, Zhang H, Lowell CA, Weiss A. PMID: 22078799; PMCID: PMC3245876.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    83. Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression. PLoS One. 2011; 6(9):e25540. Markegard E, Trager E, Yang CW, Zhang W, Weiss A, Roose JP. PMID: 21966541; PMCID: PMC3180458.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    84. SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling. Mol Cell Biol. 2011 Nov; 31(22):4550-62. Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T. PMID: 21930792; PMCID: PMC3209250.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    85. Feedback circuits monitor and adjust basal Lck-dependent events in T cell receptor signaling. Sci Signal. 2011 Sep 13; 4(190):ra59. Schoenborn JR, Tan YX, Zhang C, Shokat KM, Weiss A. PMID: 21917715; PMCID: PMC4080844.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    86. Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells. Small GTPases. 2011 Sep; 2(5):282-288. Limnander A, Weiss A. PMID: 22292132; PMCID: PMC3265820.
      View in: PubMed   Mentions: 11     Fields:    
    87. Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148. J Biol Chem. 2011 Jun 24; 286(25):22101-12. Stepanek O, Kalina T, Draber P, Skopcova T, Svojgr K, Angelisova P, Horejsi V, Weiss A, Brdicka T. PMID: 21543337; PMCID: PMC3121354.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    88. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature. 2011 Apr 28; 472(7344):471-5. Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. PMID: 21525931; PMCID: PMC3084546.
      View in: PubMed   Mentions: 334     Fields:    Translation:HumansAnimalsCells
    89. Stim1, PKCd and RasGRP proteins set a threshold for pro-apoptotic Erk signaling during B cell development (109.6). The Journal of Immunology. 2011 Apr 1; 186(1_Supplement):109.6-109.6. Limnander LA, Depeille DP, Freedman FT, Liou LJ, Leitges LM, Kurosaki KT, Roose RJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    90. Impact of TLR9 on hyper-responsive ITAM signaling in a mouse model of SLE (47.24). The Journal of Immunology. 2011 Apr 1; 186(1_Supplement):47.24-47.24. Mills MR, Lam LV, Tobler TD, Oksenberg ON, Cresalia CN, Anderson AM, Mao MJ, Weiss WA, Hermiston HM. .
      View in: Publisher Site   Mentions:
    91. A novel analog-sensitive allele of Csk reveals its kinase-independent role in the regulation of T cell receptor signaling (109.35). The Journal of Immunology. 2011 Apr 1; 186(1_Supplement):109.35-109.35. Tan TY, Schoenborn SJ, Zhang ZC, Shokat SK, Weiss WA. .
      View in: Publisher Site   Mentions:
    92. Regulation of thymocyte positive selection and motility by GIT2 (113.9). The Journal of Immunology. 2011 Apr 1; 186(1_Supplement):113.9-113.9. Phee PH, Dzhagalov DI, Mollenauer MM, Wang WY, Irvine ID, Robey RE, Weiss WA. .
      View in: Publisher Site   Mentions:
    93. Titration of CD45 expression regulates sequential tolerance checkpoints during B cell development (45.2). The Journal of Immunology. 2011 Apr 1; 186(1_Supplement):45.2-45.2. Zikherman ZJ, Doan DK, Raschke RW, Weiss WA. .
      View in: Publisher Site   Mentions:
    94. A genetically selective inhibitor reveals ZAP-70 kinase-dependent checkpoints in T cell development (64.15). The Journal of Immunology. 2011 Apr 1; 186(1_Supplement):64.15-64.15. Au-Yeung AB, Cheng CD, Zhang ZC, Shokat SK, Weiss WA. .
      View in: Publisher Site   Mentions:
    95. STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development. Nat Immunol. 2011 May; 12(5):425-33. Limnander A, Depeille P, Freedman TS, Liou J, Leitges M, Kurosaki T, Roose JP, Weiss A. PMID: 21441934; PMCID: PMC3623929.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    96. Differential requirements for CD45 in NK-cell function reveal distinct roles for Syk-family kinases. Blood. 2011 Mar 17; 117(11):3087-95. Hesslein DG, Palacios EH, Sun JC, Beilke JN, Watson SR, Weiss A, Lanier LL. PMID: 21245479; PMCID: PMC3062311.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    97. The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. J Immunol. 2011 Feb 15; 186(4):1923-33. Liontos LM, Dissanayake D, Ohashi PS, Weiss A, Dragone LL, McGlade CJ. PMID: 21220694.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    98. A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity. Nat Immunol. 2010 Dec; 11(12):1085-92. Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, Shokat KM, Weiss A. PMID: 21037577; PMCID: PMC3711183.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    99. Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16234-9. Beinke S, Phee H, Clingan JM, Schlessinger J, Matloubian M, Weiss A. PMID: 20805505; PMCID: PMC2941278.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    100. Regulation of thymocyte positive selection and motility by GIT2. Nat Immunol. 2010 Jun; 11(6):503-11. Phee H, Dzhagalov I, Mollenauer M, Wang Y, Irvine DJ, Robey E, Weiss A. PMID: 20431621; PMCID: PMC3620668.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    101. ZAP-70: an essential kinase in T-cell signaling. Cold Spring Harb Perspect Biol. 2010 May; 2(5):a002279. Wang H, Kadlecek TA, Au-Yeung BB, Goodfellow HE, Hsu LY, Freedman TS, Weiss A. PMID: 20452964; PMCID: PMC2857167.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansAnimalsCells
    102. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development. Immunity. 2010 Mar 26; 32(3):342-54. Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A. PMID: 20346773; PMCID: PMC2865198.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    103. The right team at the right time to go for a home run: tyrosine kinase activation by the TCR. Nat Immunol. 2010 Feb; 11(2):101-4. Weiss A. PMID: 20084063.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    104. Chapter 95 CD45. Handbook of Cell Signaling. 2010 Jan 1; 743-748. Hermiston HM, Gupta GV, Weiss WA. .
      View in: Publisher Site   Mentions:
    105. Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response. Proc Natl Acad Sci U S A. 2009 Dec 08; 106(49):20699-704. Deindl S, Kadlecek TA, Cao X, Kuriyan J, Weiss A. PMID: 19920178; PMCID: PMC2778570.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    106. SLAP, a regulator of immunoreceptor ubiquitination, signaling, and trafficking. Immunol Rev. 2009 Nov; 232(1):218-28. Dragone LL, Shaw LA, Myers MD, Weiss A. PMID: 19909366.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    107. A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity. J Exp Med. 2009 Oct 26; 206(11):2527-41. Hsu LY, Tan YX, Xiao Z, Malissen M, Weiss A. PMID: 19841086; PMCID: PMC2768860.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    108. TCR signal transduction: opening the black box. J Immunol. 2009 Oct 15; 183(8):4821-7. Weiss A. PMID: 19801506.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    109. Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes. Sci Signal. 2009 Apr 14; 2(66):pt2. Chakraborty AK, Das J, Zikherman J, Yang M, Govern CC, Ho M, Weiss A, Roose J. PMID: 19366993; PMCID: PMC2755093.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    110. A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity (49.6). The Journal of Immunology. 2009 Apr 1; 182(1_Supplement):49.6-49.6. Hsu HL, Tan TY, Weiss WA. .
      View in: Publisher Site   Mentions:
    111. An allelic series of CD45 dosages uncouples basal and inducible TCR signaling during thymic development (84.13). The Journal of Immunology. 2009 Apr 1; 182(1_Supplement):84.13-84.13. Zikherman ZJ, Watson WS, Jenne JC, Raschke RW, Goodnow GC, Weiss WA. .
      View in: Publisher Site   Mentions:
    112. Role of GIT2 in T cell migration and development (95.8). The Journal of Immunology. 2009 Apr 1; 182(1_Supplement):95.8-95.8. Phee PH, Mollenauer MM, Weiss WA. .
      View in: Publisher Site   Mentions:
    113. A chemical-genetic approach to inhibit Csk activates T cells independently of the T cell receptor (35.4). The Journal of Immunology. 2009 Apr 1; 182(1_Supplement):35.4-35.4. Schoenborn SJ, Zhang ZC, Shokat SK, Weiss WA. .
      View in: Publisher Site   Mentions:
    114. Identifying ZAP-70 kinase-dependent and -independent functions in T cells using a chemical genetic approach (35.5). The Journal of Immunology. 2009 Apr 1; 182(1_Supplement):35.5-35.5. Au-Yeung AB, Levin LS, Zhang ZC, Shokat SK, Weiss WA. .
      View in: Publisher Site   Mentions:
    115. PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background. J Immunol. 2009 Apr 01; 182(7):4093-106. Zikherman J, Hermiston M, Steiner D, Hasegawa K, Chan A, Weiss A. PMID: 19299707; PMCID: PMC2765978.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    116. The structure, regulation, and function of ZAP-70. Immunol Rev. 2009 Mar; 228(1):41-57. Au-Yeung BB, Deindl S, Hsu LY, Palacios EH, Levin SE, Kuriyan J, Weiss A. PMID: 19290920.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    117. The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis. Blood. 2009 May 14; 113(20):4942-54. Senis YA, Tomlinson MG, Ellison S, Mazharian A, Lim J, Zhao Y, Kornerup KN, Auger JM, Thomas SG, Dhanjal T, Kalia N, Zhu JW, Weiss A, Watson SP. PMID: 19246339; PMCID: PMC2686144.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    118. Antigen receptor signaling in the rheumatic diseases. Arthritis Res Ther. 2009; 11(1):202. Zikherman J, Weiss A. PMID: 19232064; PMCID: PMC2688213.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    119. Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell. 2009 Jan 23; 136(2):337-51. Das J, Ho M, Zikherman J, Govern C, Yang M, Weiss A, Chakraborty AK, Roose JP. PMID: 19167334; PMCID: PMC2662698.
      View in: PubMed   Mentions: 218     Fields:    Translation:HumansAnimalsCells
    120. Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):546-51. Hermiston ML, Zikherman J, Tan AL, Lam VC, Cresalia NM, Oksenberg N, Goren N, Brassat D, Oksenberg JR, Weiss A. PMID: 19129486; PMCID: PMC2626740.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    121. Origin of the sharp boundary that discriminates positive and negative selection of thymocytes. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):528-33. Prasad A, Zikherman J, Das J, Roose JP, Weiss A, Chakraborty AK. PMID: 19098101; PMCID: PMC2626737.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    122. Alternative splicing of CD45: the tip of the iceberg. Immunity. 2008 Dec 19; 29(6):839-41. Zikherman J, Weiss A. PMID: 19100695.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    123. Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18895-900. Louvet C, Szot GL, Lang J, Lee MR, Martinier N, Bollag G, Zhu S, Weiss A, Bluestone JA. PMID: 19015530; PMCID: PMC2596241.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    124. B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency. J Exp Med. 2008 Nov 24; 205(12):2755-61. Gupta VA, Hermiston ML, Cassafer G, Daikh DI, Weiss A. PMID: 19001138; PMCID: PMC2585841.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    125. The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes. Nat Immunol. 2008 May; 9(5):522-32. Mingueneau M, Sansoni A, Grégoire C, Roncagalli R, Aguado E, Weiss A, Malissen M, Malissen B. PMID: 18408722.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    126. Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling. J Biol Chem. 2008 May 30; 283(22):15419-30. Levin SE, Zhang C, Kadlecek TA, Shokat KM, Weiss A. PMID: 18378687; PMCID: PMC2397475.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    127. Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling. Immunity. 2008 Feb; 28(2):183-96. Zhu JW, Brdicka T, Katsumoto TR, Lin J, Weiss A. PMID: 18249142; PMCID: PMC2265106.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    128. Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions. Immunity. 2007 Dec; 27(6):912-26. Siggs OM, Miosge LA, Yates AL, Kucharska EM, Sheahan D, Brdicka T, Weiss A, Liston A, Goodnow CC. PMID: 18093540; PMCID: PMC3163119.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    129. Distinct roles for Syk and ZAP-70 during early thymocyte development. J Exp Med. 2007 Jul 09; 204(7):1703-15. Palacios EH, Weiss A. PMID: 17606633; PMCID: PMC2118636.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    130. Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues. J Histochem Cytochem. 2007 Oct; 55(10):1039-48. Schmalzigaug R, Phee H, Davidson CE, Weiss A, Premont RT. PMID: 17565117.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    131. Structural basis for the inhibition of tyrosine kinase activity of ZAP-70. Cell. 2007 May 18; 129(4):735-46. Deindl S, Kadlecek TA, Brdicka T, Cao X, Weiss A, Kuriyan J. PMID: 17512407.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    132. Coupling Ca2+ store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases. J Cell Biol. 2007 Apr 23; 177(2):317-28. Chung SC, Limnander A, Kurosaki T, Weiss A, Korenbrot JI. PMID: 17452533; PMCID: PMC2064139.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    133. Generation and characterization of GIT1 and GIT2 deficient mice (87.18). The Journal of Immunology. 2007 Apr 1; 178(1_Supplement):s131-s131. Phee PH, Weiss WA. .
      View in: Publisher Site   Mentions:
    134. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Mol Cell Biol. 2007 Apr; 27(7):2732-45. Roose JP, Mollenauer M, Ho M, Kurosaki T, Weiss A. PMID: 17283063; PMCID: PMC1899892.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    135. The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T-mediated virulence. J Clin Invest. 2007 Feb; 117(2):419-27. Balachandran P, Dragone L, Garrity-Ryan L, Lemus A, Weiss A, Engel J. PMID: 17235393; PMCID: PMC1765809.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    136. Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18202-7. Dragone LL, Myers MD, White C, Gadwal S, Sosinowski T, Gu H, Weiss A. PMID: 17110436; PMCID: PMC1838730.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    137. ZAP-70 Enhances IgM Signaling in Chronic Lymphocytic Leukemia Cells Independent of Its Tyrosine Kinase Activity. Blood. 2006 Nov 16; 108(11):585-585. Chen CL, Huynh HL, Weiss WA, Kipps KT. .
      View in: Publisher Site   Mentions:
    138. The Phenotypic Consequences of an Activating Mutation in the Juxtamembrane Wedge of CD45 Is Sensitive to Genetic Modifiers. Blood. 2006 Nov 16; 108(11):1730-1730. Hermiston HM, Cresalia CN, Lam LV, Tan TA, Weiss WA. .
      View in: Publisher Site   Mentions:
    139. Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4. J Exp Med. 2006 Jul 10; 203(7):1733-44. Nirula A, Ho M, Phee H, Roose J, Weiss A. PMID: 16785309; PMCID: PMC2118337.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    140. Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production. Proc Natl Acad Sci U S A. 2006 May 02; 103(18):7012-7. Hesslein DG, Takaki R, Hermiston ML, Weiss A, Lanier LL. PMID: 16627620; PMCID: PMC1459010.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    141. Small molecule inhibition of ZAP-70 kinase activity. The FASEB Journal. 2006 Mar 1; 20(5):lb64-lb65. Levin LS, Zhang ZC, Shokat SK, Weiss WA. .
      View in: Publisher Site   Mentions:
    142. SRC-like adaptor protein regulates B cell development and function. J Immunol. 2006 Jan 01; 176(1):335-45. Dragone LL, Myers MD, White C, Sosinowski T, Weiss A. PMID: 16365426.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    143. Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex. Nat Immunol. 2006 Jan; 7(1):57-66. Myers MD, Sosinowski T, Dragone LL, White C, Band H, Gu H, Weiss A. PMID: 16327786.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    144. The juxtamembrane wedge negatively regulates CD45 function in B cells. Immunity. 2005 Dec; 23(6):635-47. Hermiston ML, Tan AL, Gupta VA, Majeti R, Weiss A. PMID: 16356861.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    145. Discovering the TCR beta-chain by subtraction. J Immunol. 2005 Sep 01; 175(5):2769-70. Weiss A. PMID: 16116159.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    146. Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. J Cell Biol. 2005 Jul 18; 170(2):285-94. Myers MD, Dragone LL, Weiss A. PMID: 16027224; PMCID: PMC2171412.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    147. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Mol Cell Biol. 2005 Jun; 25(11):4426-41. Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A. PMID: 15899849; PMCID: PMC1140631.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    148. Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases. Mol Cell Biol. 2005 Jun; 25(12):4924-33. Brdicka T, Kadlecek TA, Roose JP, Pastuszak AW, Weiss A. PMID: 15923611; PMCID: PMC1140569.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    149. Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1. Nat Immunol. 2005 Jun; 6(6):608-17. Phee H, Abraham RT, Weiss A. PMID: 15864311.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    150. Twisting tails exposed: the evidence for TCR conformational change. J Exp Med. 2005 Feb 21; 201(4):489-92. Levin SE, Weiss A. PMID: 15728230; PMCID: PMC2213060.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    151. SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase. J Biol Chem. 2004 Dec 31; 279(53):55089-96. Tomlinson MG, Heath VL, Turck CW, Watson SP, Weiss A. PMID: 15492005.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    152. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene. 2004 Oct 18; 23(48):7990-8000. Palacios EH, Weiss A. PMID: 15489916.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansAnimalsCells
    153. Regulated expression of the receptor-like tyrosine phosphatase CD148 on hemopoietic cells. J Immunol. 2004 Aug 15; 173(4):2324-30. Lin J, Zhu JW, Baker JE, Weiss A. PMID: 15294945.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    154. Lymphocyte activation. Current Opinion in Immunology. 2004 Jun 1; 16(3):285-287. Weiss WA, Cambier CJ. .
      View in: Publisher Site   Mentions:
    155. A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse. J Immunol. 2004 May 01; 172(9):5441-9. Kane LP, Mollenauer MN, Weiss A. PMID: 15100285.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    156. T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization. J Exp Med. 2004 Apr 05; 199(7):981-91. Crotzer VL, Mabardy AS, Weiss A, Brodsky FM. PMID: 15067034; PMCID: PMC2211883.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    157. Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat Rev Immunol. 2004 Apr; 4(4):301-8. Abraham RT, Weiss A. PMID: 15057788.
      View in: PubMed   Mentions: 247     Fields:    Translation:HumansAnimalsCells
    158. Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nat Immunol. 2004 Apr; 5(4):435-42. Andres PG, Howland KC, Nirula A, Kane LP, Barron L, Dresnek D, Sadra A, Imboden J, Weiss A, Abbas AK. PMID: 15004555.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    159. Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec. Mol Cell Biol. 2004 Mar; 24(6):2455-66. Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A. PMID: 14993283; PMCID: PMC355844.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    160. T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS Biol. 2003 Nov; 1(2):E53. Roose JP, Diehn M, Tomlinson MG, Lin J, Alizadeh AA, Botstein D, Brown PO, Weiss A. PMID: 14624253; PMCID: PMC261890.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    161. The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling. J Cell Biol. 2003 Aug 18; 162(4):673-82. Lin J, Weiss A. PMID: 12913111; PMCID: PMC2173795.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    162. Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization. J Immunol. 2003 Jul 15; 171(2):860-6. Kuhné MR, Lin J, Yablonski D, Mollenauer MN, Ehrlich LI, Huppa J, Davis MM, Weiss A. PMID: 12847255.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    163. The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunol Rev. 2003 Apr; 192:7-20. Kane LP, Weiss A. PMID: 12670391.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    164. Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domains. J Biol Chem. 2003 May 30; 278(22):20389-94. Hartgroves LC, Lin J, Langen H, Zech T, Weiss A, Harder T. PMID: 12646565.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    165. Chapter 114 CD45. Handbook of Cell Signaling. 2003 Jan 1; (Annu. Rev. Immunol.121994):689-691. Xu XZ, Hermiston HM, Weiss WA. .
      View in: Publisher Site   Mentions:
    166. Dynamics of p56lck translocation to the T cell immunological synapse following agonist and antagonist stimulation. Immunity. 2002 Dec; 17(6):809-22. Ehrlich LI, Ebert PJ, Krummel MF, Weiss A, Davis MM. PMID: 12479826.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    167. Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription. Mol Cell Biol. 2002 Aug; 22(16):5962-74. Kane LP, Mollenauer MN, Xu Z, Turck CW, Weiss A. PMID: 12138205; PMCID: PMC133991.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    168. It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. Trends Immunol. 2002 Aug; 23(8):413-20. Kane LP, Lin J, Weiss A. PMID: 12133805.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    169. Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms. Nat Immunol. 2002 Aug; 3(8):764-71. Xu Z, Weiss A. PMID: 12134145.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    170. The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells. Cell Growth Differ. 2002 Jul; 13(7):285-96. Xu Z, Stokoe D, Kane LP, Weiss A. PMID: 12133897.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    171. Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. J Clin Invest. 2002 Jan; 109(1):9-14. Hermiston ML, Xu Z, Majeti R, Weiss A. PMID: 11781344; PMCID: PMC150828.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    172. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet. 2001 Sep; 29(1):23-4. Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR. PMID: 11528386.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    173. The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection. Immunity. 2001 Sep; 15(3):457-66. Sosinowski T, Killeen N, Weiss A. PMID: 11567635.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    174. Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. J Biol Chem. 2001 Nov 30; 276(48):45207-16. Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, Perlmutter RM. PMID: 11487585.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    175. Regulatory mechanisms for receptor protein tyrosine phosphatases. Chem Rev. 2001 Aug; 101(8):2441-8. Majeti R, Weiss A. PMID: 11749382.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    176. Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT. Mol Cell Biol. 2001 Jul; 21(13):4208-18. Yablonski D, Kadlecek T, Weiss A. PMID: 11390650; PMCID: PMC87082.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    177. Endogenous CD28 expressed on myeloma cells up-regulates interleukin-8 production: implications for multiple myeloma progression. Blood. 2001 Jul 01; 98(1):187-93. Shapiro VS, Mollenauer MN, Weiss A. PMID: 11418479.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    178. Identification of the minimal tyrosine residues required for linker for activation of T cell function. J Biol Chem. 2001 Aug 03; 276(31):29588-95. Lin J, Weiss A. PMID: 11395491.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    179. A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. J Biol Chem. 2001 Jun 29; 276(26):24341-7. Lynch KW, Weiss A. PMID: 11306584.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    180. Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation. Mol Cell Biol. 2001 Apr; 21(7):2393-403. Baker JE, Majeti R, Tangye SG, Weiss A. PMID: 11259588; PMCID: PMC86872.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    181. A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT. EMBO J. 2001 Feb 01; 20(3):457-65. Ku GM, Yablonski D, Manser E, Lim L, Weiss A. PMID: 11157752; PMCID: PMC133476.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    182. Characterization of promoter region and genomic structure of the murine and human genes encoding Src like adapter protein. Gene. 2001 Jan 10; 262(1-2):267-73. Kratchmarova I, Sosinowski T, Weiss A, Witter K, Vincenz C, Pandey A. PMID: 11179692.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    183. Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65. Adv Immunol. 2001; 79:93-128. Yablonski D, Weiss A. PMID: 11680012.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    184. Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. J Immunol. 2001 Jan 01; 166(1):656-61. Elder ME, Skoda-Smith S, Kadlecek TA, Wang F, Wu J, Weiss A. PMID: 11123350.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    185. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nat Immunol. 2001 Jan; 2(1):37-44. Kane LP, Andres PG, Howland KC, Abbas AK, Weiss A. PMID: 11135576.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    186. T cell receptor signalling. J Cell Sci. 2001 Jan; 114(Pt 2):243-4. Lin J, Weiss A. PMID: 11148124.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    187. An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell. 2000 Dec 22; 103(7):1059-70. Majeti R, Xu Z, Parslow TG, Olson JL, Daikh DI, Killeen N, Weiss A. PMID: 11163182.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    188. Lymphocytes with a complex: adapter proteins in antigen receptor signaling. Immunol Today. 2000 Nov; 21(11):584-91. Tomlinson MG, Lin J, Weiss A. PMID: 11094263.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    189. Signal transduction by the TCR for antigen. Curr Opin Immunol. 2000 Jun; 12(3):242-9. Kane LP, Lin J, Weiss A. PMID: 10781399.
      View in: PubMed   Mentions: 125     Fields:    Translation:Cells
    190. HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1. Immunity. 2000 Apr; 12(4):399-408. Liou J, Kiefer F, Dang A, Hashimoto A, Cobb MH, Kurosaki T, Weiss A. PMID: 10795738.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    191. Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling. J Exp Med. 2000 Feb 07; 191(3):463-74. Sosinowski T, Pandey A, Dixit VM, Weiss A. PMID: 10662792; PMCID: PMC2195826.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    192. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation. J Biol Chem. 2000 Jan 21; 275(3):2185-90. Kuhne MR, Ku G, Weiss A. PMID: 10636924.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    193. Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. J Exp Med. 2000 Jan 17; 191(2):355-64. Witherden D, van Oers N, Waltzinger C, Weiss A, Benoist C, Mathis D. PMID: 10637279.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    194. A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. Mol Cell Biol. 2000 Jan; 20(1):70-80. Lynch KW, Weiss A. PMID: 10594010; PMCID: PMC85051.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    195. Localization of LAT in glycolipid-enriched microdomains is required for T cell activation. J Biol Chem. 1999 Oct 08; 274(41):28861-4. Lin J, Weiss A, Finco TS. PMID: 10506128.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    196. Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression. J Immunol. 1999 Sep 01; 163(5):2610-20. Chu DH, van Oers NS, Malissen M, Harris J, Elder M, Weiss A. PMID: 10453000.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    197. Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. Proc Natl Acad Sci U S A. 1999 May 11; 96(10):5704-9. Lagunoff M, Majeti R, Weiss A, Ganem D. PMID: 10318948; PMCID: PMC21924.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    198. Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling function in lymphocytes. Mol Cell Biol. 1999 Jan; 19(1):948-56. Zhao Q, Williams BL, Abraham RT, Weiss A. PMID: 9858619; PMCID: PMC83953.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    199. The adapter proteins LAT and SLP-76 are required for T-cell activation. Cold Spring Harb Symp Quant Biol. 1999; 64:265-74. Finco TS, Yablonski D, Lin J, Weiss A. PMID: 11232295.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    200. Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: requirement for CD28 up-regulation of RE/AP. J Immunol. 1998 Dec 15; 161(12):6455-8. Shapiro VS, Mollenauer MN, Weiss A. PMID: 9862666.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    201. Differential requirements for ZAP-70 in TCR signaling and T cell development. J Immunol. 1998 Nov 01; 161(9):4688-94. Kadlecek TA, van Oers NS, Lefrancois L, Olson S, Finlay D, Chu DH, Connolly K, Killeen N, Weiss A. PMID: 9794398.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    202. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity. 1998 Nov; 9(5):617-26. Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. PMID: 9846483.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansCells
    203. A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK. EMBO J. 1998 Oct 01; 17(19):5647-57. Yablonski D, Kane LP, Qian D, Weiss A. PMID: 9755165; PMCID: PMC1170893.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    204. Switching signals on or off by receptor dimerization. Cell. 1998 Aug 07; 94(3):277-80. Weiss A, Schlessinger J. PMID: 9708728.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    205. Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science. 1998 Jul 17; 281(5375):413-6. Yablonski D, Kuhne MR, Kadlecek T, Weiss A. PMID: 9665884.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    206. Lymphocyte activation and effector functions Turning lymphocytes on and off. Current Opinion in Immunology. 1998 Jun 1; 10(3):243-244. DeFranco DA, Weiss WA. .
      View in: Publisher Site   Mentions:
    207. Anti-peptide antibodies detect conformational changes of the inter-SH2 domain of ZAP-70 due to binding to the zeta chain and to intramolecular interactions. J Biol Chem. 1998 Apr 10; 273(15):8916-21. Grazioli L, Germain V, Weiss A, Acuto O. PMID: 9535874.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    208. Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs. J Immunol. 1998 Jan 01; 160(1):163-70. van Oers NS, Love PE, Shores EW, Weiss A. PMID: 9551968.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    209. Itk and Fyn make independent contributions to T cell activation. J Exp Med. 1997 Dec 15; 186(12):2069-73. Liao XC, Littman DR, Weiss A. PMID: 9396778; PMCID: PMC2199174.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    210. Itk negatively regulates induction of T cell proliferation by CD28 costimulation. J Exp Med. 1997 Jul 21; 186(2):221-8. Liao XC, Fournier S, Killeen N, Weiss A, Allison JP, Littman DR. PMID: 9221751; PMCID: PMC2198978.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    211. CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites. Mol Cell Biol. 1997 Jul; 17(7):4051-8. Shapiro VS, Truitt KE, Imboden JB, Weiss A. PMID: 9199340; PMCID: PMC232258.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    212. ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domains. J Cell Biol. 1997 Jun 30; 137(7):1639-49. Huby RD, Iwashima M, Weiss A, Ley SC. PMID: 9199177; PMCID: PMC2137816.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    213. The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction. J Exp Med. 1997 May 19; 185(10):1877-82. Wu J, Zhao Q, Kurosaki T, Weiss A. PMID: 9151714; PMCID: PMC2196311.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    214. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. J Exp Med. 1997 Apr 07; 185(7):1253-9. Qian D, Lev S, van Oers NS, Dikic I, Schlessinger J, Weiss A. PMID: 9104812; PMCID: PMC2196260.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    215. T cell antigen receptor signal transduction. Curr Opin Cell Biol. 1997 Apr; 9(2):205-12. Qian D, Weiss A. PMID: 9069257.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    216. The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. EMBO J. 1996 Nov 15; 15(22):6251-61. Chu DH, Spits H, Peyron JF, Rowley RB, Bolen JB, Weiss A. PMID: 8947048; PMCID: PMC452448.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    217. c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J Exp Med. 1996 Nov 01; 184(5):1663-9. Shapiro VS, Mollenauer MN, Greene WC, Weiss A. PMID: 8920856; PMCID: PMC2192877.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    218. Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene. J Exp Med. 1996 Nov 01; 184(5):2031-6. Taylor N, Bacon KB, Smith S, Jahn T, Kadlecek TA, Uribe L, Kohn DB, Gelfand EW, Weiss A, Weinberg K. PMID: 8920891; PMCID: PMC2192882.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    219. alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity. 1996 Nov; 5(5):429-36. van Oers NS, Lowin-Kropf B, Finlay D, Connolly K, Weiss A. PMID: 8934570.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    220. Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. J Exp Med. 1996 Jul 01; 184(1):295-300. Fry AM, Lanier LL, Weiss A. PMID: 8691146; PMCID: PMC2192670.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    221. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity. 1996 Jun; 4(6):593-602. Wu J, Motto DG, Koretzky GA, Weiss A. PMID: 8673706.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    222. SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction. J Biol Chem. 1996 Apr 26; 271(17):9976-81. Straus DB, Chan AC, Patai B, Weiss A. PMID: 8626636.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    223. Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. J Exp Med. 1996 Mar 01; 183(3):1053-62. van Oers NS, Killeen N, Weiss A. PMID: 8642247; PMCID: PMC2192313.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    224. Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling. J Exp Med. 1996 Feb 01; 183(2):611-20. Qian D, Mollenauer MN, Weiss A. PMID: 8627172; PMCID: PMC2192449.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    225. CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation. Mol Cell Biol. 1995 Dec; 15(12):6820-8. Crooks ME, Littman DR, Carter RH, Fearon DT, Weiss A, Stein PH. PMID: 8524248; PMCID: PMC230936.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    226. Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. J Exp Med. 1995 Oct 01; 182(4):1057-65. Gelfand EW, Weinberg K, Mazer BD, Kadlecek TA, Weiss A. PMID: 7561679; PMCID: PMC2192291.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    227. Molecular and genetic insights into T-cell antigen receptor signaling. Ann N Y Acad Sci. 1995 Sep 07; 766:149-56. Weiss A, Kadlecek T, Iwashima M, Chan A, Van Oers N. PMID: 7486651.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    228. Molecular and genetic insights into the role of protein tyrosine kinases in T cell receptor signaling. Clin Immunol Immunopathol. 1995 Sep; 76(3 Pt 2):S158-62. Weiss A. PMID: 7554459.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    229. A functional T-cell receptor signaling pathway is required for p95vav activity. Mol Cell Biol. 1995 Aug; 15(8):4337-46. Wu J, Katzav S, Weiss A. PMID: 7623828; PMCID: PMC230673.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    230. Multiple kinases mediate T-cell-receptor signaling. Trends Biochem Sci. 1995 Feb; 20(2):59-64. Howe LR, Weiss A. PMID: 7701563.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    231. The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav. J Biol Chem. 1994 Dec 23; 269(51):32579-85. Katzav S, Sutherland M, Packham G, Yi T, Weiss A. PMID: 7798261.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    232. ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells. Immunity. 1994 Nov; 1(8):675-85. van Oers NS, Killeen N, Weiss A. PMID: 7600293.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    233. The role of protein kinase C in the regulation of extracellular signal-regulated kinase by the T cell antigen receptor. Eur J Immunol. 1994 Oct; 24(10):2462-8. Izquierdo M, Leevers SJ, Williams DH, Marshall CJ, Weiss A, Cantrell D. PMID: 7925576.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    234. The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation. EMBO J. 1994 Sep 01; 13(17):4002-10. Desai DM, Sap J, Silvennoinen O, Schlessinger J, Weiss A. PMID: 8076596; PMCID: PMC395320.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    235. GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Mol Cell Biol. 1994 Jul; 14(7):4435-42. Sieh M, Batzer A, Schlessinger J, Weiss A. PMID: 7516467; PMCID: PMC358815.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    236. GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Molecular and Cellular Biology. 1994 Jul 1; 14(7):4435-4442. Sieh SM, Batzer BA, Schlessinger SJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    237. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science. 1994 Jun 10; 264(5165):1596-9. Elder ME, Lin D, Clever J, Chan AC, Hope TJ, Weiss A, Parslow TG. PMID: 8202712.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    238. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science. 1994 Jun 10; 264(5165):1599-601. Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo WL, Iwashima M, Parslow TG, Weiss A. PMID: 8202713.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    239. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J Immunol. 1994 May 15; 152(10):4758-66. Chan AC, van Oers NS, Tran A, Turka L, Law CL, Ryan JC, Clark EA, Weiss A. PMID: 8176201.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    240. The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase. Mol Cell Biol. 1994 May; 14(5):3392-402. Stein PH, Fraser JD, Weiss A. PMID: 8164687; PMCID: PMC358704.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    241. The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase. Molecular and Cellular Biology. 1994 May 1; 14(5):3392-3402. Stein SP, Fraser FJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    242. The Cytoplasmic Domain of CD28 Is both Necessary and Sufficient for Costimulation of Interleukin-2 Secretion and Association with Phosphatidylinositol 3'-Kinase. Molecular and Cellular Biology. 1994 May 1; 14(5):3392-3402. Stein SP, Fraser FJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    243. Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex. J Biol Chem. 1994 Apr 22; 269(16):12310-9. Law CL, Sidorenko SP, Chandran KA, Draves KE, Chan AC, Weiss A, Edelhoff S, Disteche CM, Clark EA. PMID: 8163536.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    244. Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. J Immunol Methods. 1994 Apr 15; 170(2):261-8. van Oers NS, Teh SJ, Irving BA, Tiong J, Weiss A, Teh HS. PMID: 7512608.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    245. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science. 1994 Feb 25; 263(5150):1136-9. Iwashima M, Irving BA, van Oers NS, Chan AC, Weiss A. PMID: 7509083.
      View in: PubMed   Mentions: 194     Fields:    Translation:HumansAnimalsCells
    246. Signal transduction by lymphocyte antigen receptors. Cell. 1994 Jan 28; 76(2):263-74. Weiss A, Littman DR. PMID: 8293463.
      View in: PubMed   Mentions: 496     Fields:    Translation:HumansAnimalsCells
    247. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol. 1994; 12:555-92. Chan AC, Desai DM, Weiss A. PMID: 8011291.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    248. Molecular and genetic insights into T cell antigen receptor signal transduction. Adv Exp Med Biol. 1994; 365:53-62. Weiss A, Iwashima M, Irving B, van Oers NS, Kadlecek TA, Straus D, Chan A. PMID: 7887313.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    249. Signal transduction events leading to T-cell lymphokine gene expression. Immunol Today. 1993 Jul; 14(7):357-62. Fraser JD, Straus D, Weiss A. PMID: 8363726.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    250. Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell. 1993 May 07; 73(3):541-54. Desai DM, Sap J, Schlessinger J, Weiss A. PMID: 8490965.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    251. T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases. Cell. 1993 Apr 23; 73(2):209-12. Weiss A. PMID: 8477442.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    252. Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med. 1993 Apr 01; 177(4):1093-103. Irving BA, Chan AC, Weiss A. PMID: 8459204; PMCID: PMC2190991.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    253. CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. EMBO J. 1993 Jan; 12(1):315-21. Sieh M, Bolen JB, Weiss A. PMID: 8428589; PMCID: PMC413208.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    254. Molecular Dissection of T-Cell Antigen Receptor Signal Transduction. Progress in Immunology Vol. VIII. 1993 Jan 1; 205-211. Iwashima IM, Chan CA, Irving IB, Straus SD, Weiss WA. .
      View in: Publisher Site   Mentions:
    255. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell. 1992 Nov 13; 71(4):649-62. Chan AC, Iwashima M, Turck CW, Weiss A. PMID: 1423621.
      View in: PubMed   Mentions: 292     Fields:    Translation:HumansCells
    256. The protein tyrosine kinase inhibitor herbimycin A, but not genistein, specifically inhibits signal transduction by the T cell antigen receptor. Int Immunol. 1992 Nov; 4(11):1201-10. Graber M, June CH, Samelson LE, Weiss A. PMID: 1472473.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    257. Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28. Mol Cell Biol. 1992 Oct; 12(10):4357-63. Fraser JD, Weiss A. PMID: 1328852; PMCID: PMC360359.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    258. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell. 1992 Aug 21; 70(4):585-93. Straus DB, Weiss A. PMID: 1505025.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansCells
    259. Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line. J Immunol. 1992 Aug 15; 149(4):1138-42. Koretzky GA, Kohmetscher MA, Kadleck T, Weiss A. PMID: 1380033.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    260. New insights into T-cell antigen receptor structure and signal transduction. Curr Opin Immunol. 1992 Jun; 4(3):246-51. Chan AC, Irving BA, Weiss A. PMID: 1418701.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    261. CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. J Exp Med. 1992 Apr 01; 175(4):1131-4. Fraser JD, Newton ME, Weiss A. PMID: 1313075; PMCID: PMC2119188.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    262. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature. 1992 Mar 05; 356(6364):71-4. Margolis B, Hu P, Katzav S, Li W, Oliver JM, Ullrich A, Weiss A, Schlessinger J. PMID: 1531699.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    263. Regulation of protein tyrosine kinase activation by the T-cell antigen receptor zeta chain. Cold Spring Harb Symp Quant Biol. 1992; 57:107-16. Weiss A, Chan AC, Iwashima M, Straus D, Irving BA. PMID: 1339649.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    264. The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proc Natl Acad Sci U S A. 1991 Oct 15; 88(20):9166-70. Chan AC, Irving BA, Fraser JD, Weiss A. PMID: 1717999; PMCID: PMC52673.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    265. Signal transduction by the T cell antigen receptor. Semin Immunol. 1991 Sep; 3(5):313-24. Weiss A, Irving BA, Tan LK, Koretzky GA. PMID: 1839225.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    266. Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5484-8. Weiss A, Koretzky G, Schatzman RC, Kadlecek T. PMID: 1712101; PMCID: PMC51901.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    267. Signaling via the inositol phospholipid pathway by T cell antigen receptor is limited by receptor number. J Immunol. 1991 May 01; 146(9):2935-43. Graber M, Bockenstedt LK, Weiss A. PMID: 1826700.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    268. Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. J Exp Med. 1991 May 01; 173(5):1247-56. Tan L, Turner J, Weiss A. PMID: 1827143; PMCID: PMC2118847.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    269. Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2037-41. Koretzky GA, Picus J, Schultz T, Weiss A. PMID: 1672451; PMCID: PMC51163.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    270. The regulation of T-cell antigen receptor signal transduction function. Transplant Proc. 1991 Feb; 23(1 Pt 1):32-3. Weiss A, Desai D, Graber M, Picus J, Koretzky G. PMID: 1990543.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    271. Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science. 1991 Jan 18; 251(4991):313-6. Fraser JD, Irving BA, Crabtree GR, Weiss A. PMID: 1846244.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansCells
    272. Molecular and genetic insights into T cell antigen receptor structure and function. Annu Rev Genet. 1991; 25:487-510. Weiss A. PMID: 1839878.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    273. Stimulation of the phosphatidylinositol pathway can induce T-cell activation. Nature. 1990 Nov 01; 348(6296):66-9. Desai DM, Newton ME, Kadlecek T, Weiss A. PMID: 2234059.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    274. Structure and function of the T cell antigen receptor. J Clin Invest. 1990 Oct; 86(4):1015-22. Weiss A. PMID: 2211998; PMCID: PMC296827.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    275. Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway. Nature. 1990 Jul 05; 346(6279):66-8. Koretzky GA, Picus J, Thomas ML, Weiss A. PMID: 2164155.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    276. T-lymphocyte-antigen interactions in transplant rejection. N Engl J Med. 1990 Feb 22; 322(8):510-7. Krensky AM, Weiss A, Crabtree G, Davis MM, Parham P. PMID: 2405272.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    277. A transfected human muscarinic receptor fails to substitute for the T cell antigen receptor complex in CD2-initiated signal transduction. Int Immunol. 1990; 2(7):615-20. Desai DM, Goldsmith MA, Weiss A. PMID: 1980618.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    278. Function of a heterologous muscarinic receptor in T cell antigen receptor signal transduction mutants. J Biol Chem. 1989 Oct 15; 264(29):17190-7. Goldsmith MA, Desai DM, Schultz T, Weiss A. PMID: 2529257.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    279. Heterogeneity of protein kinase C isoenzyme gene expression in human T cell lines. Protein kinase C-beta is not required for several T cell functions. J Immunol. 1989 Sep 01; 143(5):1692-5. Koretzky GA, Wahi M, Newton ME, Weiss A. PMID: 2788192.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    280. Ligand-induced association between the T-cell antigen receptor and two glycoproteins. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7133-7. Fraser JD, Goldsmith MA, Weiss A. PMID: 2789381; PMCID: PMC298009.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    281. Use of somatic cell mutants to study the signal transduction function of the T cell antigen receptor. Adv Exp Med Biol. 1989; 254:25-33. Goldsmith MA, Bockenstedt LK, Dazin P, Weiss A. PMID: 2573246.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    282. The lysine residue in the membrane-spanning domain of the beta chain is necessary for cell surface expression of the T cell antigen receptor. J Exp Med. 1988 Dec 01; 168(6):1971-8. Morley BJ, Chin KN, Newton ME, Weiss A. PMID: 2974063; PMCID: PMC2189156.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    283. At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor. Proc Natl Acad Sci U S A. 1988 Nov; 85(22):8613-7. Goldsmith MA, Dazin PF, Weiss A. PMID: 3263650; PMCID: PMC282509.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    284. The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor. J Immunol. 1988 Sep 15; 141(6):1904-11. Bockenstedt LK, Goldsmith MA, Dustin M, Olive D, Springer TA, Weiss A. PMID: 2459194.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    285. New clues about T-cell antigen receptor complex function. Immunol Today. 1988 Jul-Aug; 9(7-8):220-2. Goldsmith MA, Weiss A. PMID: 3076421.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    286. The Initiation of Human T Lymphocyte Activation (Part 2 of 2). . 1988 Jul 1; 42:262-279. Imboden IJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    287. The Initiation of Human T Lymphocyte Activation (Part 1 of 2). . 1988 Jul 1; 42:246-261. Imboden IJ, Weiss WA. .
      View in: Publisher Site   Mentions:
    288. Early signal transduction by the antigen receptor without commitment to T cell activation. Science. 1988 May 20; 240(4855):1029-31. Goldsmith MA, Weiss A. PMID: 3259335.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    289. Function of the antigen receptor in T cell activation. Adv Exp Med Biol. 1988; 234:195-211. Goldsmith MA, Weiss A. PMID: 3063086.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    290. Generation and analysis of a T-lymphocyte somatic mutant for studying molecular aspects of signal transduction by the antigen receptor. Ann N Y Acad Sci. 1988; 546:91-103. Goldsmith MA, Weiss A. PMID: 3073703.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    291. The initiation of human T lymphocyte activation. Prog Allergy. 1988; 42:246-79. Imboden JB, Weiss A. PMID: 2845427.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    292. Role of the T3/T-Cell Antigen Receptor Complex in T-Cell Activation. The T-Cell Receptors. 1988 Jan 1; 133-149. Manger MB, Imboden IJ, Weiss WA. .
      View in: Publisher Site   Mentions:
      View in: Publisher Site   Mentions:
    294. The activation of T lymphocytes. Rheum Dis Clin North Am. 1987 Dec; 13(3):411-30. Bockenstedt LK, Goldsmith MA, Koretzky GA, Weiss A. PMID: 2963355.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    295. Identification and sequence of a fourth human T cell antigen receptor chain. Nature. 1987 Dec 10-16; 330(6148):569-72. Loh EY, Lanier LL, Turck CW, Littman DR, Davis MM, Chien YH, Weiss A. PMID: 2825032.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    296. Functional competency of T cell antigen receptors in human thymus. J Immunol. 1987 Nov 15; 139(10):3245-50. Weiss A, Dazin PF, Shields R, Fu SM, Lanier LL. PMID: 3500209.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    297. Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines. J Exp Med. 1987 Nov 01; 166(5):1579-84. Phillips JH, Weiss A, Gemlo BT, Rayner AA, Lanier LL. PMID: 3500263; PMCID: PMC2189654.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    298. The T-cell antigen receptor regulates sustained increases in cytoplasmic free Ca2+ through extracellular Ca2+ influx and ongoing intracellular Ca2+ mobilization. Biochem J. 1987 Nov 01; 247(3):695-700. Imboden JB, Weiss A. PMID: 3426556; PMCID: PMC1148468.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    299. The gamma T-cell antigen receptor. J Clin Immunol. 1987 Nov; 7(6):429-40. Lanier LL, Serafini AT, Ruitenberg JJ, Cwirla S, Federspiel NA, Phillips JH, Allison JP, Weiss A. PMID: 3320076.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    300. The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies. J Immunol. 1987 Oct 15; 139(8):2755-60. Manger B, Weiss A, Imboden J, Laing T, Stobo JD. PMID: 3116093.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    301. Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proc Natl Acad Sci U S A. 1987 Oct; 84(19):6879-83. Goldsmith MA, Weiss A. PMID: 3309950; PMCID: PMC299188.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    302. Molecular diversity of the human T-gamma constant region genes. Science. 1987 Aug 28; 237(4818):1051-5. Pelicci PG, Subar M, Weiss A, Dalla-Favera R, Littman DR. PMID: 3112943.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    303. Cell surface T3 expression requires the presence of both alpha- and beta-chains of the T cell receptor. J Immunol. 1987 Jul 15; 139(2):625-8. Saito T, Weiss A, Gunter KC, Shevach EM, Germain RN. PMID: 2955045.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    304. Requirements for triggering of lysis by cytolytic T lymphocyte clones. J Immunol. 1987 Jun 01; 138(11):3646-53. Lancki DW, Weiss A, Fitch FW. PMID: 2953785.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    305. Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex. Nature. 1987 Apr 2-8; 326(6112):505-7. Gunter KC, Germain RN, Kroczek RA, Saito T, Yokoyama WM, Chan C, Weiss A, Shevach EM. PMID: 3104795.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    306. The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. J Exp Med. 1987 Apr 01; 165(4):1076-94. Lanier LL, Federspiel NA, Ruitenberg JJ, Phillips JH, Allison JP, Littman D, Weiss A. PMID: 2435832; PMCID: PMC2188591.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    307. Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene. J Immunol. 1987 Apr 01; 138(7):2169-76. Weiss A, Shields R, Newton M, Manger B, Imboden J. PMID: 3104454.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    308. Characterization of an expressed CD3-associated Ti gamma-chain reveals C gamma domain polymorphism. Nature. 1987 Mar 5-11; 326(6108):85-8. Littman DR, Newton M, Crommie D, Ang SL, Seidman JG, Gettner SN, Weiss A. PMID: 3102973.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    309. A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor. J Exp Med. 1987 Feb 01; 165(2):395-407. Durand DB, Bush MR, Morgan JG, Weiss A, Crabtree GR. PMID: 3102668; PMCID: PMC2188523.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    310. Cell surface molecules and early events involved in human T lymphocyte activation. Adv Immunol. 1987; 41:1-38. Weiss A, Imboden JB. PMID: 2961214.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    311. The role of the antigen receptor/T3 complex in T-cell activation. Adv Exp Med Biol. 1987; 213:45-9. Weiss A, Imboden J, Hardy K, Stobo J. PMID: 2957896.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    312. Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature. 1987 Jan 8-14; 325(7000):125-30. Saito T, Weiss A, Miller J, Norcross MA, Germain RN. PMID: 3027582.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    313. Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus. Nature. 1986 Nov 20-26; 324(6094):268-70. Lanier LL, Weiss A. PMID: 3491323.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    314. Distinct epitopes on the T cell antigen receptor of HPB-ALL tumor cells identified by monoclonal antibodies. J Immunol. 1986 Oct 01; 137(7):2286-92. Lanier LL, Ruitenberg JJ, Allison JP, Weiss A. PMID: 2428866.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    315. Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells. J Immunol. 1986 Aug 01; 137(3):819-25. Weiss A, Manger B, Imboden J. PMID: 3088111.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    316. Differential effect of cyclosporin A on activation signaling in human T cell lines. J Clin Invest. 1986 May; 77(5):1501-6. Manger B, Hardy KJ, Weiss A, Stobo JD. PMID: 2422208; PMCID: PMC424552.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    317. The role of the T3/antigen receptor complex in T-cell activation. Annu Rev Immunol. 1986; 4:593-619. Weiss A, Imboden J, Hardy K, Manger B, Terhorst C, Stobo J. PMID: 2939858.
      View in: PubMed   Mentions: 165     Fields:    Translation:HumansAnimalsCells
    318. A transferrin receptor antibody represents one signal for the induction of IL 2 production by a human T cell line. J Immunol. 1986 Jan; 136(2):532-8. Manger B, Weiss A, Hardy KJ, Stobo JD. PMID: 3001178.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    319. T cell activation: differences in the signals required for IL 2 production by nonactivated and activated T cells. J Immunol. 1985 Dec; 135(6):3669-73. Manger B, Weiss A, Weyand C, Goronzy J, Stobo JD. PMID: 3934263.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    320. Transmembrane signalling by the T3-antigen receptor complex. Immunol Today. 1985 Nov; 6(11):328-31. Imboden JB, Weiss A, Stobo JD. PMID: 25291003.
      View in: PubMed   Mentions: 2     Fields:    
    321. Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature. 1985 Aug 15-21; 316(6029):606-9. Ohashi PS, Mak TW, Van den Elsen P, Yanagi Y, Yoshikai Y, Calman AF, Terhorst C, Stobo JD, Weiss A. PMID: 4033759.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    322. Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes. J Immunol. 1985 Mar; 134(3):1599-603. Wiskocil R, Weiss A, Imboden J, Kamin-Lewis R, Stobo J. PMID: 3918105.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    323. The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium. J Immunol. 1985 Feb; 134(2):663-5. Imboden JB, Weiss A, Stobo JD. PMID: 3871211.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    324. Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med. 1984 Nov 01; 160(5):1284-99. Weiss A, Stobo JD. PMID: 6208306; PMCID: PMC2187507.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansAnimalsCells
    325. Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A. 1984 Jul; 81(13):4169-73. Weiss A, Imboden J, Shoback D, Stobo J. PMID: 6234599; PMCID: PMC345390.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    326. The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J Immunol. 1984 Jul; 133(1):123-8. Weiss A, Wiskocil RL, Stobo JD. PMID: 6327821.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansCells
    327. The role of T3 in the activation of human T cells. J Clin Immunol. 1984 May; 4(3):165-73. Weiss A, Imboden J, Wiskocil R, Stobo J. PMID: 6203926.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    328. Inhibition of cytolytic T lymphocyte clones reactive with Moloney leukemia virus-associated antigens by monoclonal antibodies: a direct approach to the study of H-2 restriction. J Immunol. 1981 Feb; 126(2):482-5. Weiss A, MacDonald HR, Cerottini JC, Brunner KT. PMID: 6450244.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    329. Antigenic specificity of the cytolytic T lymphocyte response to murine sarcoma virus-induced tumors. III. Characterization of cytolytic T lymphocyte clones specific for Moloney leukemia virus-associated cell surface antigens. J Exp Med. 1980 Nov 01; 152(5):1210-25. Weiss A, Brunner KT, MacDonald HR, Cerottini JC. PMID: 6159445; PMCID: PMC2185999.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    330. Suppression of rat renal allograft rejection by antigen and antibody. Immunol Rev. 1980; 49:127-65. Stuart FP, McKearn TJ, Weiss A, Fitch FW. PMID: 6989746.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    331. Selective suppression of humoral and cell-mediated immune responses to rat alloantigens by monoclonal antibodies produced by hybridoma cell lines. Transplant Proc. 1979 Mar; 11(1):932-5. McKearn TJ, Weiss A, Stuart FP, Fitch FW. PMID: 377725.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    332. Immune reactivity of cells from long-term rat renal allograft survivors. Transplantation. 1978 Nov; 26(5):346-52. Weiss A, Stuart FP, Fitch FW. PMID: 151955.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    333. Immunological memory is regulated in the enhanced rat renal allograft recipient. Nature. 1978 Jun 22; 273(5664):662-4. Weiss A, Fitch FW, McKearn TJ, Stuart FP. PMID: 351414.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    334. Graft enhancement and antiidiotypic antibody. Lymphocytes from long-term rat renal allograft recipients have normal responsiveness in vitro. Transplant Proc. 1978 Jun; 10(2):367-72. Fitch FW, Weiss A, McKearn TJ, Stuart FP. PMID: 79259.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    335. Suppression of the plaque-forming cell response by macrophages present in the normal rat spleen. J Immunol. 1978 Feb; 120(2):357-9. Weiss A, Fitch FW. PMID: 621383.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    336. Selective suppression of reactivity to rat histocompatibility antigens by hybridoma antibodies. Curr Top Microbiol Immunol. 1978; 81:61-5. McKearn TJ, Sarmiento M, Weiss A, Stuart FP, Fitch FW. PMID: 308442.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    337. Absence of immunologic memory in recipients of enhanced renal allografts. Surg Forum. 1978; 29:330-3. Weiss A, Stuart FP, Fitch FW. PMID: 162608.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    338. Macrophages suppress CTL generation in rat mixed leukocyte cultures. J Immunol. 1977 Aug; 119(2):510-6. Weiss A, Fitch FW. PMID: 142114.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    339. Suppression of adult rat lymphoid proliferative responses by homologous neonatal serum. J Immunol. 1977 Mar; 118(3):1121-3. Weiss A. PMID: 139446.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    340. Antigen cap formation in cultured fibroblasts: a reflection of membrane fluidity and of cell motility. Proc Natl Acad Sci U S A. 1972 Sep; 69(9):2456-9. Edidin M, Weiss A. PMID: 4560687; PMCID: PMC426964.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells