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Mark Von Zastrow, MD, PhD

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
Address600 16th St
San Francisco CA 94158
Phone415-476-7871
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Receptors and Second Messengers for Pain and Analgesia
    NIH/NINDS P01NS053709Sep 1, 2007 - Jun 30, 2013
    Role: Co-Investigator
    2007 Molecular Pharmacology Gordon Research Conference
    NIH R13DA022784Jan 15, 2007 - Dec 31, 2007
    Role: Principal Investigator
    Mechanisms Regulating Endocytosis of Opioid Receptors
    NIH R01DA012864Dec 1, 1999 - May 31, 2021
    Role: Principal Investigator
    Post-endocytic Sorting of Opioid Receptors
    NIH K02DA000439Sep 1, 1999 - Dec 30, 2010
    Role: Principal Investigator
    Presynaptic Mechanisms of Neural Plasticity
    NIH/NIDA P01DA010154Sep 5, 1997 - May 31, 2012
    Role: Co-Investigator
    Membrane Trafficking of Opioid and Adrenergic Receptors
    NIH R01DA010711Jan 15, 1997 - Jan 31, 2019
    Role: Principal Investigator
    MEMBRANE TRAFFICKING OF OPIOID RECEPTORS
    NIH R37DA010711Jan 15, 1997 - Jan 31, 2014
    Role: Principal Investigator
    MEMBRANE TRAFFICKING OF OPIOID RECEPTORS
    NIH R29DA010711Jan 15, 1997 - Mar 31, 2004
    Role: Principal Investigator
    MECHANISMS OF RECEPTOR INTERNALIZATION IN DRUG ADDICTION
    NIH K21DA000218Sep 30, 1994 - Aug 31, 1999
    Role: Principal Investigator
    Extracellular Matrix Protein enhancement of Phagocytosis
    NIH R01GM038330Dec 1, 1986 - Nov 30, 2007
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Proteomic approaches to investigate regulated trafficking and signaling of GPCRs. Mol Pharmacol. 2020 Dec 22. von Zastrow M. PMID: 33361190.
      View in: PubMed   Mentions:    Fields:    
    2. Chemical Biology Approaches for Genome-Wide Screening of GPCR Trafficking. The FASEB Journal. 2020 Apr 1; 34(S1):1-1. Braden Lobingier, Nikoleta Tsvetanova, Mark von Zastrow. .
      View in: Publisher Site   Mentions:
    3. A High-throughput CRISPR Interference Screen to Dissect Functional Regulators of GPCR/cAMP Signaling. The FASEB Journal. 2020 Apr 1; 34(S1):1-1. Khairunnisa Mentari Semesta, Ruilin Tian, Martin Kampmann, Mark von Zastrow, Nikoleta G. Tsvetanova. .
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    4. A Discrete Presynaptic Vesicle Cycle for Neuromodulator Receptors. Neuron. 2019 Dec 1. Damien Jullié, Miriam Stoeber, Jean-Baptiste Sibarita, Hanna L. Zieger, Thomas M. Bartol, Seksiri Arttamangkul, Terrence J. Sejnowski, Eric Hosy, Mark von Zastrow. .
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    5. Endosomal Phosphatidylinositol 3-Kinase Is Essential for Canonical GPCR Signaling. Mol Pharmacol. 2017 Jan; 91(1):65-73. Uchida Y, Rutaganira FU, Jullié D, Shokat KM, von Zastrow M. PMID: 27821547.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. Modulating neuromodulation by receptor membrane traffic in the endocytic pathway. Neuron. 2012 Oct 04; 76(1):22-32. von Zastrow M, Williams JT. PMID: 23040804.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    7. Opioid Receptor Trafficking. The Opiate Receptors. 2011 Jan 1; 389-405. Mark von Zastrow. .
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    8. Membrane traffic in the post-genomic era. Genome Biology. 2010 May 1; 11(5):119. Peter Hein, Mark von Zastrow. .
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    9. Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications. Drug Alcohol Depend. 2010 May 01; 108(3):166-71. von Zastrow M. PMID: 20338697.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    10. Chapter 27 Agonist-Induced Desensitization and Endocytosis of G-protein-Coupled Receptors. Handbook of Cell Signaling. 2010 Jan 1; 177-183. Michael Tanowitz, Mark von Zastrow. .
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    11. Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions. Cell. 2008 Apr 1; 133(2):376. Robin M. Shaw, Alex J. Fay, Manojkumar A. Puthenveedu, Mark von Zastrow, Yuh-Nung Jan, Lily Y. Jan. .
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    12. Signaling on the endocytic pathway. Curr Opin Cell Biol. 2007 Aug; 19(4):436-45. von Zastrow M, Sorkin A. PMID: 17662591.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    13. Endocytosis. Encyclopedia of Molecular Cell Biology and Molecular Medicine. 2006 Sep 15. Hadiya A. Watson, Mark Von Zastrow, Beverly Wendland. .
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    14. Regulated Membrane Trafficking and Proteolysis of GPCRs. The G Protein-Coupled Receptors Handbook. 2005 Jan 1; 95-105. James N. Hislop, Mark von Zastrow. .
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    15. Identification of Protein Interactions by Yeast Two-Hybrid Screening and Coimmunoprecipitation. Receptor Signal Transduction Protocols. 2004 Jan 1; 259:353-369. Michael Tanowitz, Mark von Zastrow. .
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    16. A walk on the wild side (of the synapse). Nature Cell Biology. 2003 Mar 1; 5(3):194-194. Mark von Zastrow. .
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    17. Chapter 31 Agonist-Induced Desensitization and Endocytosis of G-Protein-Coupled Receptors. Handbook of Cell Signaling. 2003 Jan 1; (Adv. Cyclic Nuc. Prot. Phos. Res.201986):181-186. Mark von Zastrow. .
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    18. Intracellular trafficking of epitope-tagged opioid receptors: Different effects of morphine and enkephalin. Peptides. 1994 Nov 1; 54(1):315-316. M von Zastrow, D Keith, P Zaki, C Evans. .
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    19. An approach to the molecular biology of opiate tolerance: identification of opiate-regulated transcripts. NIDA Res Monogr. 1991; 111:85-95. vonZastrow M, Barchas JD, Eberwine JH. PMID: 1775186.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
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