Ira Mellman, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
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Varies CA 00000
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    Collapse Biography 
    Collapse Education and Training
    Yale University School of Medicine, New Haven, CTPhDGenetics
    The Rockefeller University, New York, NYpostdocImmunology/Cell Biology
    Oberlin College, Oberlin, OHAB

    Collapse Research 
    Collapse Research Activities and Funding
    Cell Biology of the Immune Response
    NIH R13AI053905Jan 15, 2003 - Dec 31, 2003
    Role: Principal Investigator
    GORDON RESEARCH CONFERENCE ON MOLECULAR MEMBRANE BIOLOGY
    NIH R13GM049679Jul 1, 1993 - Jun 30, 1994
    Role: Principal Investigator
    DEVELOPMENTAL CELL BIOLOGY OF DENDRITIC CELLS
    NIH R37AI034098Mar 1, 1993 - Jul 31, 2008
    Role: Principal Investigator
    CELL BIOLOGY OF FC RECEPTOR FUNCTION
    NIH R01AI034098Mar 1, 1993 - Feb 28, 1998
    Role: Principal Investigator
    CELL BIOLOGY OF MHC CLASS II ANTIGEN PRESENTATION
    NIH R01GM033904Jul 1, 1984 - Mar 31, 1999
    Role: Principal Investigator
    Molecular Sorting During Intracellular Transport
    NIH R01GM029765Jul 1, 1981 - Dec 30, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Molecular determinants of response to PD-L1 blockade across tumor types. Nat Commun. 2021 06 25; 12(1):3969. Banchereau R, Leng N, Zill O, Sokol E, Liu G, Pavlick D, Maund S, Liu LF, Kadel E, Baldwin N, Jhunjhunwala S, Nickles D, Assaf ZJ, Bower D, Patil N, McCleland M, Shames D, Molinero L, Huseni M, Sanjabi S, Cummings C, Mellman I, Mariathasan S, Hegde P, Powles T. PMID: 34172722.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    2. Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. Nat Commun. 2021 06 07; 12(1):3355. Khan Z, Hammer C, Carroll J, Di Nucci F, Acosta SL, Maiya V, Bhangale T, Hunkapiller J, Mellman I, Albert ML, McCarthy MI, Chandler GS. PMID: 34099659.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues. Nat Immunol. 2021 May; 22(5):571-585. Kapoor VN, Müller S, Keerthivasan S, Brown M, Chalouni C, Storm EE, Castiglioni A, Lane R, Nitschke M, Dominguez CX, Astarita JL, Krishnamurty AT, Carbone CB, Senbabaoglu Y, Wang AW, Wu X, Cremasco V, Roose-Girma M, Tam L, Doerr J, Chen MZ, Lee WP, Modrusan Z, Yang YA, Bourgon R, Sandoval W, Shaw AS, de Sauvage FJ, Mellman I, Moussion C, Turley SJ. PMID: 33903764.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade. J Immunother Cancer. 2021 Apr; 9(4). Banchereau R, Chitre AS, Scherl A, Wu TD, Patil NS, de Almeida P, Kadel Iii EE, Madireddi S, Au-Yeung A, Takahashi C, Chen YJ, Modrusan Z, McBride J, Nersesian R, El-Gabry EA, Robida MD, Hung JC, Kowanetz M, Zou W, McCleland M, Caplazi P, Eshgi ST, Koeppen H, Hegde PS, Mellman I, Mathews WR, Powles T, Mariathasan S, Grogan J, O'Gorman WE. PMID: 33827905.
      View in: PubMed   Mentions: 1     Fields:    
    5. Activation of NF-?B and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation. Proc Natl Acad Sci U S A. 2021 Feb 23; 118(8). Zhou Y, Bastian IN, Long MD, Dow M, Li W, Liu T, Ngu RK, Antonucci L, Huang JY, Phung QT, Zhao XH, Banerjee S, Lin XJ, Wang H, Dang B, Choi S, Karin D, Su H, Ellisman MH, Jamieson C, Bosenberg M, Cheng Z, Haybaeck J, Kenner L, Fisch KM, Bourgon R, Hernandez G, Lill JR, Liu S, Carter H, Mellman I, Karin M, Shalapour S. PMID: 33602823.
      View in: PubMed   Mentions:    Fields:    
    6. Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers. J Exp Med. 2021 Jan 04; 218(1). Byrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Mellman I, Duffy D, Albert ML, Milieu Intérieur Consortium . PMID: 33175106.
      View in: PubMed   Mentions: 3     Fields:    
    7. Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation. PLoS One. 2020; 15(11):e0238484. Nalle SC, Barreira da Silva R, Zhang H, Decker M, Chalouni C, Xu M, Posthuma G, de Mazière A, Klumperman J, Baz Morelli A, Fleire SJ, Verkman AS, Trombetta ES, Albert ML, Mellman I. PMID: 33232321.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12288-12294. Khan Z, Di Nucci F, Kwan A, Hammer C, Mariathasan S, Rouilly V, Carroll J, Fontes M, Ley Acosta S, Guardino E, Chen-Harris H, Bhangale T, Mellman I, Rosenberg J, Powles T, Hunkapiller J, Chandler GS, Albert ML. PMID: 32430334.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Dexamethasone premedication suppresses vaccine-induced immune responses against cancer. Oncoimmunology. 2020 05 13; 9(1):1758004. Vormehr M, Lehar S, Kranz LM, Tahtinen S, Oei Y, Javinal V, Delamarre L, Walzer KC, Diken M, Kreiter S, Mellman I, Sahin U, Schartner JM, Türeci Ö. PMID: 32923115.
      View in: PubMed   Mentions:
    10. Mutation position is an important determinant for predicting cancer neoantigens. J Exp Med. 2020 04 06; 217(4). Capietto AH, Jhunjhunwala S, Pollock SB, Lupardus P, Wong J, Hänsch L, Cevallos J, Chestnut Y, Fernandez A, Lounsbury N, Nozawa T, Singh M, Fan Z, de la Cruz CC, Phung QT, Taraborrelli L, Haley B, Lill JR, Mellman I, Bourgon R, Delamarre L. PMID: 31940002.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    11. Peripheral T cell expansion predicts tumour infiltration and clinical response. Nature. 2020 03; 579(7798):274-278. Wu TD, Madireddi S, de Almeida PE, Banchereau R, Chen YJ, Chitre AS, Chiang EY, Iftikhar H, O'Gorman WE, Au-Yeung A, Takahashi C, Goldstein LD, Poon C, Keerthivasan S, de Almeida Nagata DE, Du X, Lee HM, Banta KL, Mariathasan S, Das Thakur M, Huseni MA, Ballinger M, Estay I, Caplazi P, Modrusan Z, Delamarre L, Mellman I, Bourgon R, Grogan JL. PMID: 32103181.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    12. Transposable element expression in tumors is associated with immune infiltration and increased antigenicity. Nat Commun. 2019 11 19; 10(1):5228. Kong Y, Rose CM, Cass AA, Williams AG, Darwish M, Lianoglou S, Haverty PM, Tong AJ, Blanchette C, Albert ML, Mellman I, Bourgon R, Greally J, Jhunjhunwala S, Chen-Harris H. PMID: 31745090.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    13. E-Cadherin is Dispensable to Maintain Langerhans Cells in the Epidermis. J Invest Dermatol. 2020 01; 140(1):132-142.e3. Brand A, Diener N, Zahner SP, Tripp C, Backer RA, Karram K, Jiang A, Mellman I, Stoitzner P, Clausen BE. PMID: 31260672.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    14. Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models. Cancer Immunol Res. 2019 06; 7(6):963-976. Xiong H, Mittman S, Rodriguez R, Pacheco-Sanchez P, Moskalenko M, Yang Y, Elstrott J, Ritter AT, Müller S, Nickles D, Arenzana TL, Capietto AH, Delamarre L, Modrusan Z, Rutz S, Mellman I, Cubas R. PMID: 31064777.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    15. The Dendritic Cell Strikes Back. Immunity. 2019 02 19; 50(2):533. Moussion C, Mellman I. PMID: 30784580.
      View in: PubMed   Mentions: 1     Fields:    
    16. The Dendritic Cell Strikes Back. Immunity. 2018 12 18; 49(6):997-999. Moussion C, Mellman I. PMID: 30566889.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    17. Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11701-E11710. Lim YW, Chen-Harris H, Mayba O, Lianoglou S, Wuster A, Bhangale T, Khan Z, Mariathasan S, Daemen A, Reeder J, Haverty PM, Forrest WF, Brauer M, Mellman I, Albert ML. PMID: 30463956.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    18. Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1). Proc Natl Acad Sci U S A. 2018 10 23; 115(43):E10119-E10126. Kowanetz M, Zou W, Gettinger SN, Koeppen H, Kockx M, Schmid P, Kadel EE, Wistuba I, Chaft J, Rizvi NA, Spigel DR, Spira A, Hirsch FR, Cohen V, Smith D, Boyd Z, Miley N, Flynn S, Leveque V, Shames DS, Ballinger M, Mocci S, Shankar G, Funke R, Hampton G, Sandler A, Amler L, Mellman I, Chen DS, Hegde PS. PMID: 30297397.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCellsCTClinical Trials
    19. The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function. Cell Rep. 2018 10 02; 25(1):80-94. Hernandez S, Qing J, Thibodeau RH, Du X, Park S, Lee HM, Xu M, Oh S, Navarro A, Roose-Girma M, Newman RJ, Warming S, Nannini M, Sampath D, Kim JM, Grogan JL, Mellman I. PMID: 30282040.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    20. TGFß attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature. 2018 02 22; 554(7693):544-548. Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Senbabaoglu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T. PMID: 29443960.
      View in: PubMed   Mentions: 674     Fields:    Translation:HumansAnimalsCells
    21. SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer. J Cell Biol. 2018 02 05; 217(2):763-777. Viotti M, Wilson C, McCleland M, Koeppen H, Haley B, Jhunjhunwala S, Klijn C, Modrusan Z, Arnott D, Classon M, Stephan JP, Mellman I. PMID: 29229751.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    22. Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy. PLoS One. 2017; 12(6):e0177920. Baharom F, Thomas OS, Lepzien R, Mellman I, Chalouni C, Smed-Sörensen A. PMID: 28591131.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    23. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017 03 31; 355(6332):1428-1433. Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. PMID: 28280247.
      View in: PubMed   Mentions: 359     Fields:    Translation:HumansAnimalsCells
    24. Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice. Nat Commun. 2017 02 21; 8:14572. Lau J, Cheung J, Navarro A, Lianoglou S, Haley B, Totpal K, Sanders L, Koeppen H, Caplazi P, McBride J, Chiu H, Hong R, Grogan J, Javinal V, Yauch R, Irving B, Belvin M, Mellman I, Kim JM, Schmidt M. PMID: 28220772.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    25. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017 03 06; 216(3):779-792. Vander Lugt B, Riddell J, Khan AA, Hackney JA, Lesch J, DeVoss J, Weirauch MT, Singh H, Mellman I. PMID: 28130292.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    26. Elements of cancer immunity and the cancer-immune set point. Nature. 2017 01 18; 541(7637):321-330. Chen DS, Mellman I. PMID: 28102259.
      View in: PubMed   Mentions: 872     Fields:    Translation:HumansAnimalsCells
    27. Natural killer cell granules converge to avoid collateral damage. J Cell Biol. 2016 Dec 19; 215(6):765-767. Ritter AT, Mellman I. PMID: 27932575.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    28. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016 09 07; 7:12742. Chung I, Reichelt M, Shao L, Akita RW, Koeppen H, Rangell L, Schaefer G, Mellman I, Sliwkowski MX. PMID: 27599456.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    29. Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule. J Immunother Cancer. 2016; 4:37. Kaufman HL, Butterfield LH, Coulie PG, Demaria S, Ferris RL, Galon J, Khleif SN, Mellman I, Ohashi PS, Overwijk WW, Topalian SL, Marincola FM. PMID: 27330810.
      View in: PubMed   Mentions:    Fields:    
    30. Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop. Oncoimmunology. 2016 Jul; 5(7):e1186323. Houot R, Gaulard P, Schreiber R, Mellman I, Lambotte O, Coulie PG, Fest T, Korman A, Levy R, Shipp M, Tarte K, Kohrt H, Marabelle A, Ansell S, Watier H, van Elsas A, Balakumaran A, Arce Vargas F, Quezada SA, Salles G, Olive D. PMID: 27622041.
      View in: PubMed   Mentions:
    31. The Human Vaccines Project: A roadmap for cancer vaccine development. Sci Transl Med. 2016 Apr 13; 8(334):334ps9. Romero P, Banchereau J, Bhardwaj N, Cockett M, Disis ML, Dranoff G, Gilboa E, Hammond SA, Hershberg R, Korman AJ, Kvistborg P, Melief C, Mellman I, Palucka AK, Redchenko I, Robins H, Sallusto F, Schenkelberg T, Schoenberger S, Sosman J, Türeci Ö, Van den Eynde B, Koff W, Coukos G. PMID: 27075624.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    32. De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute. Cancer Immunol Res. 2016 Apr; 4(4):279-88. Mellman I, Hubbard-Lucey VM, Tontonoz MJ, Kalos MD, Chen DS, Allison JP, Drake CG, Levitsky H, Lonberg N, van der Burg SH, Fearon DT, Wherry EJ, Lowy I, Vonderheide RH, Hwu P. PMID: 27036972.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    33. MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade. Immunity. 2016 Mar 15; 44(3):609-621. Ebert PJR, Cheung J, Yang Y, McNamara E, Hong R, Moskalenko M, Gould SE, Maecker H, Irving BA, Kim JM, Belvin M, Mellman I. PMID: 26944201.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimalsCells
    34. Voices of biotech. Nat Biotechnol. 2016 Mar; 34(3):270-5. Amit I, Baker D, Barker R, Berger B, Bertozzi C, Bhatia S, Biffi A, Demichelis F, Doudna J, Dowdy SF, Endy D, Helmstaedter M, Junca H, June C, Kamb S, Khvorova A, Kim DH, Kim JS, Krishnan Y, Lakadamyali M, Lappalainen T, Lewin S, Liao J, Loman N, Lundberg E, Lynd L, Martin C, Mellman I, Miyawaki A, Mummery C, Nelson K, Paz J, Peralta-Yahya P, Picotti P, Polyak K, Prather K, Qin J, Quake S, Regev A, Rogers JA, Shetty R, Sommer M, Stevens M, Stolovitzky G, Takahashi M, Tang F, Teichmann S, Torres-Padilla ME, Tripathi L, Vemula P, Verdine G, Vollmer F, Wang J, Ying JY, Zhang F, Zhang T. PMID: 26963549.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Is all cancer therapy immunotherapy? Sci Transl Med. 2015 Nov 25; 7(315):315fs48. Belvin M, Mellman I. PMID: 26606965.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    36. Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):14664-9. Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C, Peng I, Jeet S, Wu LC, Mellman I, Delamarre L, Austin CD. PMID: 26561586.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    37. Cancer immunotherapy. Neo approaches to cancer vaccines. Science. 2015 May 15; 348(6236):760-1. Delamarre L, Mellman I, Yadav M. PMID: 25977539.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    38. Immunotherapy: The path to win the war on cancer? Cell. 2015 Apr 09; 161(2):185-6. Topalian SL, Wolchok JD, Chan TA, Mellman I, Palucka K, Banchereau J, Rosenberg SA, Dane Wittrup K. PMID: 26042237.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    39. Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. J Immunol. 2015 May 01; 194(9):4422-30. Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren KJ, McInerney GM, Karlsson Hedestam GB, Mellman I, Smed-Sörensen A. PMID: 25801434.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    40. ß-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):2823-8. Fu C, Liang X, Cui W, Ober-Blöbaum JL, Vazzana J, Shrikant PA, Lee KP, Clausen BE, Mellman I, Jiang A. PMID: 25730849.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    41. Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse. Mol Biol Cell. 2015 Apr 01; 26(7):1273-85. Reversat A, Yuseff MI, Lankar D, Malbec O, Obino D, Maurin M, Penmatcha NV, Amoroso A, Sengmanivong L, Gundersen GG, Mellman I, Darchen F, Desnos C, Pierobon P, Lennon-Duménil AM. PMID: 25631815.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    42. Single-molecule optical methods analyzing receptor tyrosine kinase activation in living cells. Methods Mol Biol. 2015; 1233:35-44. Chung I, Mellman I. PMID: 25319887.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    43. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014 Nov 27; 515(7528):563-7. Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS. PMID: 25428504.
      View in: PubMed   Mentions: 1641     Fields:    Translation:HumansCellsCTClinical Trials
    44. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 2014 Nov 27; 515(7528):572-6. Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR, Delamarre L. PMID: 25428506.
      View in: PubMed   Mentions: 385     Fields:    Translation:AnimalsCells
    45. Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature. 2014 May 08; 509(7499):240-4. Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Mazière A, Klumperman J, Schlatter M, Delamarre L, Mellman I. PMID: 24695226.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    46. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol. 2014 Feb; 15(2):161-7. Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. PMID: 24362890.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    47. Endocytosis and cancer. Cold Spring Harb Perspect Biol. 2013 Dec 01; 5(12):a016949. Mellman I, Yarden Y. PMID: 24296170.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansCells
    48. A Nobel Prize for membrane traffic: vesicles find their journey's end. J Cell Biol. 2013 Nov 25; 203(4):559-61. Mellman I, Emr SD. PMID: 24215073.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    49. Antibody therapeutics in cancer. Science. 2013 Sep 13; 341(6151):1192-8. Sliwkowski MX, Mellman I. PMID: 24031011.
      View in: PubMed   Mentions: 180     Fields:    Translation:Humans
    50. ß-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8? T cells. J Leukoc Biol. 2014 Jan; 95(1):179-90. Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. PMID: 24023259.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    51. Dendritic cells: master regulators of the immune response. Cancer Immunol Res. 2013 Sep; 1(3):145-9. Mellman I. PMID: 24777676.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    52. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013 Jul 25; 39(1):1-10. Chen DS, Mellman I. PMID: 23890059.
      View in: PubMed   Mentions: 1259     Fields:    Translation:HumansCells
    53. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. J Exp Med. 2013 Jun 03; 210(6):1069-77. Oh J, Wu N, Baravalle G, Cohn B, Ma J, Lo B, Mellman I, Ishido S, Anderson M, Shin JS. PMID: 23712430.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    54. Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation. J Exp Med. 2013 May 06; 210(5):1049-63. Cohn L, Chatterjee B, Esselborn F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L. PMID: 23569326.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    55. Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways. J Cell Biol. 2012 Dec 24; 199(7):1117-30. Lo B, Strasser G, Sagolla M, Austin CD, Junttila M, Mellman I. PMID: 23266956.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    56. Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 2012 Sep 06; 120(10):2011-20. Chatterjee B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I. PMID: 22791285.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    57. Profile of Ira Mellman. Interview by Prashant Nair. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8790-2. Mellman I. PMID: 22645337.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    58. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8820-7. Ma JK, Platt MY, Eastham-Anderson J, Shin JS, Mellman I. PMID: 22566640.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    59. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Apr 03; 109(14):5299-304. Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. PMID: 22431598.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansCells
    60. Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. PLoS Pathog. 2012; 8(3):e1002572. Smed-Sörensen A, Chalouni C, Chatterjee B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I. PMID: 22412374.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    61. Cancer immunotherapy comes of age. Nature. 2011 Dec 21; 480(7378):480-9. Mellman I, Coukos G, Dranoff G. PMID: 22193102.
      View in: PubMed   Mentions: 1052     Fields:    Translation:HumansCells
    62. Remembering Ralph Steinman. J Exp Med. 2011 Nov 21; 208(12):2343-7. Banchereau J, Cohn F, Inaba K, Muller B, Mellman I, Nathan C, Nussenzweig M, O'Garra A, Seder B, Schuler G, Sher A. PMID: 22216461.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    63. Retrospective. Ralph M. Steinman (1943-2011). Science. 2011 Oct 28; 334(6055):466. Mellman I, Nussenzweig M. PMID: 22034425.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    64. Ralph Steinman (1943-2011). Nature. 2011 Oct 26; 478(7370):460. Nussenzweig MC, Mellman I. PMID: 22031432.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    65. A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. J Cell Biol. 2011 Apr 04; 193(1):219-33. Francis SS, Sfakianos J, Lo B, Mellman I. PMID: 21444686.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    66. AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3ß (GSK-3ß) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane. J Biol Chem. 2011 May 13; 286(19):16879-90. Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. PMID: 21383016.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    67. Harnessing dendritic cells for immunotherapy. Semin Immunol. 2011 Feb; 23(1):2-11. Delamarre L, Mellman I. PMID: 21377379.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    68. Cell biology redux. Mol Biol Cell. 2010 Nov 15; 21(22):3809-10. Mellman I. PMID: 21079023.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. Designing vaccines based on biology of human dendritic cell subsets. Immunity. 2010 Oct 29; 33(4):464-78. Palucka K, Banchereau J, Mellman I. PMID: 21029958.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    70. Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly. Biochem Biophys Res Commun. 2010 Sep 17; 400(2):271-7. Togawa A, Sfakianos J, Ishibe S, Suzuki S, Fujigaki Y, Kitagawa M, Mellman I, Cantley LG. PMID: 20728428.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    71. Immunology. Beta-catenin balances immunity. Science. 2010 Aug 13; 329(5993):767-9. Mellman I, Clausen BE. PMID: 20705838.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    72. Monocyte-derived dendritic cells exhibit increased levels of lysosomal proteolysis as compared to other human dendritic cell populations. PLoS One. 2010 Aug 02; 5(8):e11949. McCurley N, Mellman I. PMID: 20689855.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    73. Trafficking guidance receptors. Cold Spring Harb Perspect Biol. 2010 Jul; 2(7):a001826. Winckler B, Mellman I. PMID: 20504966.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    74. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature. 2010 Apr 01; 464(7289):783-7. Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. PMID: 20208517.
      View in: PubMed   Mentions: 218     Fields:    Translation:HumansAnimalsCells
    75. Antigen processing and presentation. Curr Opin Immunol. 2010 Feb; 22(1):78-80. Mellman I, Cresswell P. PMID: 20172702.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    76. Mature dendritic cells use endocytic receptors to capture and present antigens. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4287-92. Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L. PMID: 20142498.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    77. Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell. 2010 Jan 19; 18(1):39-51. Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML. PMID: 20152176.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    78. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res. 2009 Sep 01; 15(17):5323-37. Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, Mellman I, Prindiville SA, Viner JL, Weiner LM, Matrisian LM. PMID: 19723653.
      View in: PubMed   Mentions: 486     Fields:    Translation:Humans
    79. Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. J Cell Biol. 2009 Jul 27; 186(2):269-82. Farr GA, Hull M, Mellman I, Caplan MJ. PMID: 19620635.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    80. Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine. 2009 May 18; 27(23):3013-21. Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. PMID: 19428913.
      View in: PubMed   Mentions: 107     Fields:    Translation:AnimalsCellsPHPublic Health
    81. Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells. Immunobiology. 2009; 214(7):495-505. Becker SM, Delamarre L, Mellman I, Andrews NW. PMID: 19157638.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    82. Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol. 2009 Jan 26; 184(2):281-96. Mao YS, Yamaga M, Zhu X, Wei Y, Sun HQ, Wang J, Yun M, Wang Y, Di Paolo G, Bennett M, Mellman I, Abrams CS, De Camilli P, Lu CY, Yin HL. PMID: 19153220.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    83. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med. 2009 Feb 16; 206(2):399-410. Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. PMID: 19153244.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    84. By the scientists, for the scientists. J Cell Biol. 2009 Jan 12; 184(1):7-9. Mellman I. PMID: 19139258.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    85. Coordinated protein sorting, targeting and distribution in polarized cells. Nat Rev Mol Cell Biol. 2008 Nov; 9(11):833-45. Mellman I, Nelson WJ. PMID: 18946473.
      View in: PubMed   Mentions: 236     Fields:    Translation:HumansAnimalsCells
    86. A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells. Traffic. 2008 Nov; 9(11):1915-24. Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. PMID: 18764819.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    87. A33 antigen displays persistent surface expression. Cancer Immunol Immunother. 2008 Jul; 57(7):1017-27. Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD. PMID: 18236042.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    88. Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond). 2008 Jun; 3(3):343-55. Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. PMID: 18510429.
      View in: PubMed   Mentions: 19     Fields:    
    89. Spinophilin participates in information transfer at immunological synapses. J Cell Biol. 2008 Apr 21; 181(2):203-11. Bloom O, Unternaehrer JJ, Jiang A, Shin JS, Delamarre L, Allen P, Mellman I. PMID: 18411312.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    90. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol. 2008 May; 9(5):551-7. Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, Xue Y, Mellman I, Banchereau J, Connolly JE. PMID: 18376401.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCells
    91. Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cell Microbiol. 2008 May; 10(5):1190-207. Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, Flavell RA, Mellman I, van der Goot FG. PMID: 18194483.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    92. Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol. 2007 Dec 17; 179(6):1133-40. Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L, Toomre D, Mellman I. PMID: 18070914.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    93. Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody. Neoplasia. 2007 Dec; 9(12):1099-110. Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. PMID: 18084617.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    94. Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity. 2007 Oct; 27(4):610-24. Jiang A, Bloom O, Ono S, Cui W, Unternaehrer J, Jiang S, Whitney JA, Connolly J, Banchereau J, Mellman I. PMID: 17936032.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    95. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007 Oct 04; 449(7162):564-9. Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, Homey B, Cao W, Wang YH, Su B, Nestle FO, Zal T, Mellman I, Schröder JM, Liu YJ, Gilliet M. PMID: 17873860.
      View in: PubMed   Mentions: 571     Fields:    Translation:HumansCells
    96. Private lives: reflections and challenges in understanding the cell biology of the immune system. Science. 2007 Aug 03; 317(5838):625-7. Mellman I. PMID: 17673653.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    97. How the rich get richer. J Exp Med. 2007 Jul 09; 204(7):1503. Rossner M, Mellman I. PMID: 17576780.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    98. How the rich get richer. J Cell Biol. 2007 Jun 18; 177(6):951. Rossner M, Mellman I. PMID: 17562793.
      View in: PubMed   Mentions: 2     Fields:    
    99. Ira Mellman: from endosomes to industry. Interview by William A Wells. J Cell Biol. 2007 May 21; 177(4):570-1. Mellman I. PMID: 17517958.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    100. Incomplete screening? Nat Immunol. 2007 May; 8(5):473. Mellman I. PMID: 17440454.
      View in: PubMed   Mentions:    Fields:    
    101. The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proc Natl Acad Sci U S A. 2007 Jan 02; 104(1):234-9. Unternaehrer JJ, Chow A, Pypaert M, Inaba K, Mellman I. PMID: 17190803.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    102. Bringing science to cancer therapy. Yale J Biol Med. 2006 Dec; 79(3-4):177-8. Mellman I. PMID: 17940629.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    103. Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic. 2007 Jan; 8(1):47-60. Schuck S, Gerl MJ, Ang A, Manninen A, Keller P, Mellman I, Simons K. PMID: 17132146.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    104. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature. 2006 Nov 02; 444(7115):115-8. Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. PMID: 17051151.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    105. Modulation of cell adhesion and motility in the immune system by Myo1f. Science. 2006 Oct 06; 314(5796):136-9. Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA. PMID: 17023661.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    106. Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. J Exp Med. 2006 Sep 04; 203(9):2049-55. Delamarre L, Couture R, Mellman I, Trombetta ES. PMID: 16908625.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    107. Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging. J Cell Biol. 2006 Mar 27; 172(7):1035-44. Hua W, Sheff D, Toomre D, Mellman I. PMID: 16567501.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    108. CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol. 2006 Mar 27; 172(7):1045-56. Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S. PMID: 16567502.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    109. Presentation of self-antigens on MHC class II molecules during dendritic cell maturation. Int Immunol. 2006 Jan; 18(1):199-209. Zwickey HL, Unternaehrer JJ, Mellman I. PMID: 16361313.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    110. Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 2005 Oct 07; 123(1):157-70. Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, Mellman I, Grinstein S. PMID: 16213220.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    111. Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. J Cell Biol. 2005 Aug 15; 170(4):595-605. Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I. PMID: 16087710.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    112. Targeting antigen to CD19 on B cells efficiently activates T cells. Int Immunol. 2005 Jul; 17(7):869-77. Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ. PMID: 15967786.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    113. The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor. FASEB J. 2005 May; 19(7):780-2. Johns TG, Mellman I, Cartwright GA, Ritter G, Old LJ, Burgess AW, Scott AM. PMID: 15774576.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    114. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science. 2005 Mar 11; 307(5715):1630-4. Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. PMID: 15761154.
      View in: PubMed   Mentions: 285     Fields:    Translation:AnimalsCells
    115. Old lysosomes, new tricks: MHC II dynamics in DCs. Trends Immunol. 2005 Feb; 26(2):72-8. Chow AY, Mellman I. PMID: 15668121.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    116. Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol. 2005; 23:975-1028. Trombetta ES, Mellman I. PMID: 15771591.
      View in: PubMed   Mentions: 381     Fields:    Translation:HumansAnimalsCells
    117. Antigen processing and presentation by dendritic cells: cell biological mechanisms. Adv Exp Med Biol. 2005; 560:63-7. Mellman I. PMID: 15932021.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    118. Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. J Immunol. 2004 Nov 15; 173(10):6119-24. Meyer zum Bueschenfelde CO, Unternaehrer J, Mellman I, Bottomly K. PMID: 15528348.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    119. Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells. J Cell Biol. 2004 Nov 08; 167(3):531-43. Ang AL, Taguchi T, Francis S, Fölsch H, Murrells LJ, Pypaert M, Warren G, Mellman I. PMID: 15534004.
      View in: PubMed   Mentions: 177     Fields:    Translation:AnimalsCells
    120. IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14467-72. Matsuo M, Nagata Y, Sato E, Atanackovic D, Valmori D, Chen YT, Ritter G, Mellman I, Old LJ, Gnjatic S. PMID: 15383663.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    121. The JEM and the JCB: a synergistic partnership. J Cell Biol. 2004 Aug 30; 166(5):611. Steinman RM, Mellman I. PMID: 15337771.
      View in: PubMed   Mentions:    Fields:    
    122. Immunotherapy: bewitched, bothered, and bewildered no more. Science. 2004 Jul 09; 305(5681):197-200. Steinman RM, Mellman I. PMID: 15247468.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    123. Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic. 2004 Jun; 5(6):449-61. Duffield A, Fölsch H, Mellman I, Caplan MJ. PMID: 15117319.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    124. The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. J Cell Biol. 2004 Mar 29; 164(7):1055-64. Chang HC, Hull M, Mellman I. PMID: 15051737.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    125. Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol. 2004 Feb; 6(2):106-12. Yeaman C, Ayala MI, Wright JR, Bard F, Bossard C, Ang A, Maeda Y, Seufferlein T, Mellman I, Nelson WJ, Malhotra V. PMID: 14743217.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    126. The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. J Cell Biol. 2003 Oct 27; 163(2):339-50. Ang AL, Fölsch H, Koivisto UM, Pypaert M, Mellman I. PMID: 14581456.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    127. The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains. J Cell Biol. 2003 Oct 27; 163(2):351-62. Fölsch H, Pypaert M, Maday S, Pelletier L, Mellman I. PMID: 14581457.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    128. Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation. J Exp Med. 2003 Jul 07; 198(1):111-22. Delamarre L, Holcombe H, Mellman I. PMID: 12835477.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    129. Computational cell biology. J Cell Biol. 2003 May 12; 161(3):463-4. Mellman I, Misteli T. PMID: 12743098.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    130. Activation of lysosomal function during dendritic cell maturation. Science. 2003 Feb 28; 299(5611):1400-3. Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I. PMID: 12610307.
      View in: PubMed   Mentions: 217     Fields:    Translation:AnimalsCells
    131. Hsc70 is required for endocytosis and clathrin function in Drosophila. J Cell Biol. 2002 Nov 11; 159(3):477-87. Chang HC, Newmyer SL, Hull MJ, Ebersold M, Schmid SL, Mellman I. PMID: 12427870.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    132. The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation. J Immunol. 2002 Nov 01; 169(9):4982-9. Holcombe H, Mellman I, Janeway CA, Bottomly K, Dittel BN. PMID: 12391212.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    133. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 2002 Aug 29; 418(6901):988-94. Chow A, Toomre D, Garrett W, Mellman I. PMID: 12198549.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    134. Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10629-34. Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett W, Old LJ, Mellman I. PMID: 12138174.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    135. Regulation and functional insights in cellular polarity, Madrid, Spain June 3-5, 2002. J Cell Biol. 2002 Jul 08; 158(1):12-6. Mellman I, Ridley A. PMID: 12141270.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    136. Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells. Mol Biol Cell. 2002 Jul; 13(7):2374-82. Sugimoto H, Sugahara M, Fölsch H, Koide Y, Nakatsu F, Tanaka N, Nishimura T, Furukawa M, Mullins C, Nakamura N, Mellman I, Ohno H. PMID: 12134076.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    137. Transferrin receptor recycling in the absence of perinuclear recycling endosomes. J Cell Biol. 2002 Mar 04; 156(5):797-804. Sheff D, Pelletier L, O'Connell CB, Warren G, Mellman I. PMID: 11877458.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    138. Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes. Mol Biol Cell. 2002 Jan; 13(1):262-75. Sheff DR, Kroschewski R, Mellman I. PMID: 11809838.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
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