Ira Mellman, PhD
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Title(s) | Professor, Biochemistry and Biophysics |
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School | School of Medicine |
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Address | Location Required Varies CA 00000
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Phone | -- |
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vCard | Download vCard |
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Biography Yale University School of Medicine, New Haven, CT | PhD | | Genetics | The Rockefeller University, New York, NY | postdoc | | Immunology/Cell Biology | Oberlin College, Oberlin, OH | AB | | |
Research ORNG Applications Bibliographic
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Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers. J Exp Med. 2021 Jan 04; 218(1).
Byrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Mellman I, Duffy D, Albert ML. PMID: 33175106.
View in: PubMed Mentions: Fields:
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Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation. PLoS One. 2020; 15(11):e0238484.
Nalle SC, Barreira da Silva R, Zhang H, Decker M, Chalouni C, Xu M, Posthuma G, de Mazière A, Klumperman J, Baz Morelli A, Fleire SJ, Verkman AS, Trombetta ES, Albert ML, Mellman I. PMID: 33232321.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
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Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12288-12294.
Khan Z, Di Nucci F, Kwan A, Hammer C, Mariathasan S, Rouilly V, Carroll J, Fontes M, Ley Acosta S, Guardino E, Chen-Harris H, Bhangale T, Mellman I, Rosenberg J, Powles T, Hunkapiller J, Chandler GS, Albert ML. PMID: 32430334.
View in: PubMed Mentions: 3 Fields: Translation: HumansCells
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Dexamethasone premedication suppresses vaccine-induced immune responses against cancer. Oncoimmunology. 2020 May 13; 9(1):1758004.
Vormehr M, Lehar S, Kranz LM, Tahtinen S, Oei Y, Javinal V, Delamarre L, Walzer KC, Diken M, Kreiter S, Mellman I, Sahin U, Schartner JM, Türeci Ö. PMID: 32923115.
View in: PubMed Mentions:
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Mutation position is an important determinant for predicting cancer neoantigens. J Exp Med. 2020 04 06; 217(4).
Capietto AH, Jhunjhunwala S, Pollock SB, Lupardus P, Wong J, Hänsch L, Cevallos J, Chestnut Y, Fernandez A, Lounsbury N, Nozawa T, Singh M, Fan Z, de la Cruz CC, Phung QT, Taraborrelli L, Haley B, Lill JR, Mellman I, Bourgon R, Delamarre L. PMID: 31940002.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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Peripheral T cell expansion predicts tumour infiltration and clinical response. Nature. 2020 03; 579(7798):274-278.
Wu TD, Madireddi S, de Almeida PE, Banchereau R, Chen YJ, Chitre AS, Chiang EY, Iftikhar H, O'Gorman WE, Au-Yeung A, Takahashi C, Goldstein LD, Poon C, Keerthivasan S, de Almeida Nagata DE, Du X, Lee HM, Banta KL, Mariathasan S, Das Thakur M, Huseni MA, Ballinger M, Estay I, Caplazi P, Modrusan Z, Delamarre L, Mellman I, Bourgon R, Grogan JL. PMID: 32103181.
View in: PubMed Mentions: 24 Fields: Translation: HumansCells
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Transposable element expression in tumors is associated with immune infiltration and increased antigenicity. Nat Commun. 2019 11 19; 10(1):5228.
Kong Y, Rose CM, Cass AA, Williams AG, Darwish M, Lianoglou S, Haverty PM, Tong AJ, Blanchette C, Albert ML, Mellman I, Bourgon R, Greally J, Jhunjhunwala S, Chen-Harris H. PMID: 31745090.
View in: PubMed Mentions: 11 Fields: Translation: HumansCells
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E-Cadherin is Dispensable to Maintain Langerhans Cells in the Epidermis. J Invest Dermatol. 2020 01; 140(1):132-142.e3.
Brand A, Diener N, Zahner SP, Tripp C, Backer RA, Karram K, Jiang A, Mellman I, Stoitzner P, Clausen BE. PMID: 31260672.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
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Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models. Cancer Immunol Res. 2019 06; 7(6):963-976.
Xiong H, Mittman S, Rodriguez R, Pacheco-Sanchez P, Moskalenko M, Yang Y, Elstrott J, Ritter AT, Müller S, Nickles D, Arenzana TL, Capietto AH, Delamarre L, Modrusan Z, Rutz S, Mellman I, Cubas R. PMID: 31064777.
View in: PubMed Mentions: 5 Fields: Translation: AnimalsCells
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The Dendritic Cell Strikes Back. Immunity. 2019 02 19; 50(2):533.
Moussion C, Mellman I. PMID: 30784580.
View in: PubMed Mentions: Fields:
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The Dendritic Cell Strikes Back. Immunity. 2018 12 18; 49(6):997-999.
Moussion C, Mellman I. PMID: 30566889.
View in: PubMed Mentions: 5 Fields: Translation: Cells
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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11701-E11710.
Lim YW, Chen-Harris H, Mayba O, Lianoglou S, Wuster A, Bhangale T, Khan Z, Mariathasan S, Daemen A, Reeder J, Haverty PM, Forrest WF, Brauer M, Mellman I, Albert ML. PMID: 30463956.
View in: PubMed Mentions: 10 Fields: Translation: HumansCells
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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1). Proc Natl Acad Sci U S A. 2018 10 23; 115(43):E10119-E10126.
Kowanetz M, Zou W, Gettinger SN, Koeppen H, Kockx M, Schmid P, Kadel EE, Wistuba I, Chaft J, Rizvi NA, Spigel DR, Spira A, Hirsch FR, Cohen V, Smith D, Boyd Z, Miley N, Flynn S, Leveque V, Shames DS, Ballinger M, Mocci S, Shankar G, Funke R, Hampton G, Sandler A, Amler L, Mellman I, Chen DS, Hegde PS. PMID: 30297397.
View in: PubMed Mentions: 31 Fields: Translation: HumansCellsCTClinical Trials
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The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function. Cell Rep. 2018 10 02; 25(1):80-94.
Hernandez S, Qing J, Thibodeau RH, Du X, Park S, Lee HM, Xu M, Oh S, Navarro A, Roose-Girma M, Newman RJ, Warming S, Nannini M, Sampath D, Kim JM, Grogan JL, Mellman I. PMID: 30282040.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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TGFß attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature. 2018 02 22; 554(7693):544-548.
Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Senbabaoglu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T. PMID: 29443960.
View in: PubMed Mentions: 386 Fields: Translation: HumansAnimalsCells
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SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer. J Cell Biol. 2018 02 05; 217(2):763-777.
Viotti M, Wilson C, McCleland M, Koeppen H, Haley B, Jhunjhunwala S, Klijn C, Modrusan Z, Arnott D, Classon M, Stephan JP, Mellman I. PMID: 29229751.
View in: PubMed Mentions: 6 Fields: Translation: HumansCells
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Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy. PLoS One. 2017; 12(6):e0177920.
Baharom F, Thomas OS, Lepzien R, Mellman I, Chalouni C, Smed-Sörensen A. PMID: 28591131.
View in: PubMed Mentions: 2 Fields: Translation: HumansCells
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T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017 03 31; 355(6332):1428-1433.
Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. PMID: 28280247.
View in: PubMed Mentions: 235 Fields: Translation: HumansAnimalsCells
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Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice. Nat Commun. 2017 02 21; 8:14572.
Lau J, Cheung J, Navarro A, Lianoglou S, Haley B, Totpal K, Sanders L, Koeppen H, Caplazi P, McBride J, Chiu H, Hong R, Grogan J, Javinal V, Yauch R, Irving B, Belvin M, Mellman I, Kim JM, Schmidt M. PMID: 28220772.
View in: PubMed Mentions: 66 Fields: Translation: HumansAnimalsCells
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Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017 03 06; 216(3):779-792.
Vander Lugt B, Riddell J, Khan AA, Hackney JA, Lesch J, DeVoss J, Weirauch MT, Singh H, Mellman I. PMID: 28130292.
View in: PubMed Mentions: 25 Fields: Translation: AnimalsCells
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Elements of cancer immunity and the cancer-immune set point. Nature. 2017 01 18; 541(7637):321-330.
Chen DS, Mellman I. PMID: 28102259.
View in: PubMed Mentions: 572 Fields: Translation: HumansAnimalsCells
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Natural killer cell granules converge to avoid collateral damage. J Cell Biol. 2016 Dec 19; 215(6):765-767.
Ritter AT, Mellman I. PMID: 27932575.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
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High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016 09 07; 7:12742.
Chung I, Reichelt M, Shao L, Akita RW, Koeppen H, Rangell L, Schaefer G, Mellman I, Sliwkowski MX. PMID: 27599456.
View in: PubMed Mentions: 15 Fields: Translation: HumansCells
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Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule. J Immunother Cancer. 2016; 4:37.
Kaufman HL, Butterfield LH, Coulie PG, Demaria S, Ferris RL, Galon J, Khleif SN, Mellman I, Ohashi PS, Overwijk WW, Topalian SL, Marincola FM. PMID: 27330810.
View in: PubMed Mentions: Fields:
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Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop. Oncoimmunology. 2016 Jul; 5(7):e1186323.
Houot R, Gaulard P, Schreiber R, Mellman I, Lambotte O, Coulie PG, Fest T, Korman A, Levy R, Shipp M, Tarte K, Kohrt H, Marabelle A, Ansell S, Watier H, van Elsas A, Balakumaran A, Arce Vargas F, Quezada SA, Salles G, Olive D. PMID: 27622041.
View in: PubMed Mentions:
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The Human Vaccines Project: A roadmap for cancer vaccine development. Sci Transl Med. 2016 Apr 13; 8(334):334ps9.
Romero P, Banchereau J, Bhardwaj N, Cockett M, Disis ML, Dranoff G, Gilboa E, Hammond SA, Hershberg R, Korman AJ, Kvistborg P, Melief C, Mellman I, Palucka AK, Redchenko I, Robins H, Sallusto F, Schenkelberg T, Schoenberger S, Sosman J, Türeci Ö, Van den Eynde B, Koff W, Coukos G. PMID: 27075624.
View in: PubMed Mentions: 44 Fields: Translation: HumansCells
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De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute. Cancer Immunol Res. 2016 Apr; 4(4):279-88.
Mellman I, Hubbard-Lucey VM, Tontonoz MJ, Kalos MD, Chen DS, Allison JP, Drake CG, Levitsky H, Lonberg N, van der Burg SH, Fearon DT, Wherry EJ, Lowy I, Vonderheide RH, Hwu P. PMID: 27036972.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimals
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MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade. Immunity. 2016 Mar 15; 44(3):609-621.
Ebert PJR, Cheung J, Yang Y, McNamara E, Hong R, Moskalenko M, Gould SE, Maecker H, Irving BA, Kim JM, Belvin M, Mellman I. PMID: 26944201.
View in: PubMed Mentions: 141 Fields: Translation: HumansAnimalsCells
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Voices of biotech. Nat Biotechnol. 2016 Mar; 34(3):270-5.
Amit I, Baker D, Barker R, Berger B, Bertozzi C, Bhatia S, Biffi A, Demichelis F, Doudna J, Dowdy SF, Endy D, Helmstaedter M, Junca H, June C, Kamb S, Khvorova A, Kim DH, Kim JS, Krishnan Y, Lakadamyali M, Lappalainen T, Lewin S, Liao J, Loman N, Lundberg E, Lynd L, Martin C, Mellman I, Miyawaki A, Mummery C, Nelson K, Paz J, Peralta-Yahya P, Picotti P, Polyak K, Prather K, Qin J, Quake S, Regev A, Rogers JA, Shetty R, Sommer M, Stevens M, Stolovitzky G, Takahashi M, Tang F, Teichmann S, Torres-Padilla ME, Tripathi L, Vemula P, Verdine G, Vollmer F, Wang J, Ying JY, Zhang F, Zhang T. PMID: 26963549.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Is all cancer therapy immunotherapy? Sci Transl Med. 2015 Nov 25; 7(315):315fs48.
Belvin M, Mellman I. PMID: 26606965.
View in: PubMed Mentions: 7 Fields: Translation: Humans
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Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):14664-9.
Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C, Peng I, Jeet S, Wu LC, Mellman I, Delamarre L, Austin CD. PMID: 26561586.
View in: PubMed Mentions: 13 Fields: Translation: AnimalsCells
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Cancer immunotherapy. Neo approaches to cancer vaccines. Science. 2015 May 15; 348(6236):760-1.
Delamarre L, Mellman I, Yadav M. PMID: 25977539.
View in: PubMed Mentions: 19 Fields: Translation: HumansCells
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Immunotherapy: The path to win the war on cancer? Cell. 2015 Apr 09; 161(2):185-6.
Topalian SL, Wolchok JD, Chan TA, Mellman I, Palucka K, Banchereau J, Rosenberg SA, Dane Wittrup K. PMID: 26042237.
View in: PubMed Mentions: 32 Fields: Translation: Humans
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Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. J Immunol. 2015 May 01; 194(9):4422-30.
Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren KJ, McInerney GM, Karlsson Hedestam GB, Mellman I, Smed-Sörensen A. PMID: 25801434.
View in: PubMed Mentions: 5 Fields: Translation: HumansCells
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ß-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):2823-8.
Fu C, Liang X, Cui W, Ober-Blöbaum JL, Vazzana J, Shrikant PA, Lee KP, Clausen BE, Mellman I, Jiang A. PMID: 25730849.
View in: PubMed Mentions: 30 Fields: Translation: AnimalsCells
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Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse. Mol Biol Cell. 2015 Apr 01; 26(7):1273-85.
Reversat A, Yuseff MI, Lankar D, Malbec O, Obino D, Maurin M, Penmatcha NV, Amoroso A, Sengmanivong L, Gundersen GG, Mellman I, Darchen F, Desnos C, Pierobon P, Lennon-Duménil AM. PMID: 25631815.
View in: PubMed Mentions: 9 Fields: Translation: AnimalsCells
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Single-molecule optical methods analyzing receptor tyrosine kinase activation in living cells. Methods Mol Biol. 2015; 1233:35-44.
Chung I, Mellman I. PMID: 25319887.
View in: PubMed Mentions: Fields: Translation: HumansCells
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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014 Nov 27; 515(7528):563-7.
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS. PMID: 25428504.
View in: PubMed Mentions: 1349 Fields: Translation: HumansCellsCTClinical Trials
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Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 2014 Nov 27; 515(7528):572-6.
Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR, Delamarre L. PMID: 25428506.
View in: PubMed Mentions: 315 Fields: Translation: AnimalsCells
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Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature. 2014 May 08; 509(7499):240-4.
Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Mazière A, Klumperman J, Schlatter M, Delamarre L, Mellman I. PMID: 24695226.
View in: PubMed Mentions: 73 Fields: Translation: AnimalsCells
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Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol. 2014 Feb; 15(2):161-7.
Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. PMID: 24362890.
View in: PubMed Mentions: 91 Fields: Translation: AnimalsCells
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Endocytosis and cancer. Cold Spring Harb Perspect Biol. 2013 Dec 01; 5(12):a016949.
Mellman I, Yarden Y. PMID: 24296170.
View in: PubMed Mentions: 111 Fields: Translation: HumansCells
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A Nobel Prize for membrane traffic: vesicles find their journey's end. J Cell Biol. 2013 Nov 25; 203(4):559-61.
Mellman I, Emr SD. PMID: 24215073.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
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Antibody therapeutics in cancer. Science. 2013 Sep 13; 341(6151):1192-8.
Sliwkowski MX, Mellman I. PMID: 24031011.
View in: PubMed Mentions: 165 Fields: Translation: Humans
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ß-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8? T cells. J Leukoc Biol. 2014 Jan; 95(1):179-90.
Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. PMID: 24023259.
View in: PubMed Mentions: 27 Fields: Translation: AnimalsCells
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Dendritic cells: master regulators of the immune response. Cancer Immunol Res. 2013 Sep; 1(3):145-9.
Mellman I. PMID: 24777676.
View in: PubMed Mentions: 51 Fields: Translation: HumansCells
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Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013 Jul 25; 39(1):1-10.
Chen DS, Mellman I. PMID: 23890059.
View in: PubMed Mentions: 912 Fields: Translation: HumansCells
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MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. J Exp Med. 2013 Jun 03; 210(6):1069-77.
Oh J, Wu N, Baravalle G, Cohn B, Ma J, Lo B, Mellman I, Ishido S, Anderson M, Shin JS. PMID: 23712430.
View in: PubMed Mentions: 28 Fields: Translation: AnimalsCells
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Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation. J Exp Med. 2013 May 06; 210(5):1049-63.
Cohn L, Chatterjee B, Esselborn F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L. PMID: 23569326.
View in: PubMed Mentions: 70 Fields: Translation: HumansAnimalsCells
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Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways. J Cell Biol. 2012 Dec 24; 199(7):1117-30.
Lo B, Strasser G, Sagolla M, Austin CD, Junttila M, Mellman I. PMID: 23266956.
View in: PubMed Mentions: 21 Fields: Translation: AnimalsCells
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Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 2012 Sep 06; 120(10):2011-20.
Chatterjee B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I. PMID: 22791285.
View in: PubMed Mentions: 82 Fields: Translation: HumansCells
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Profile of Ira Mellman. Interview by Prashant Nair. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8790-2.
Mellman I. PMID: 22645337.
View in: PubMed Mentions: Fields: Translation: Cells
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MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8820-7.
Ma JK, Platt MY, Eastham-Anderson J, Shin JS, Mellman I. PMID: 22566640.
View in: PubMed Mentions: 23 Fields: Translation: AnimalsCells
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Apr 03; 109(14):5299-304.
Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. PMID: 22431598.
View in: PubMed Mentions: 170 Fields: Translation: HumansCells
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Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. PLoS Pathog. 2012; 8(3):e1002572.
Smed-Sörensen A, Chalouni C, Chatterjee B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I. PMID: 22412374.
View in: PubMed Mentions: 37 Fields: Translation: HumansCells
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Cancer immunotherapy comes of age. Nature. 2011 Dec 21; 480(7378):480-9.
Mellman I, Coukos G, Dranoff G. PMID: 22193102.
View in: PubMed Mentions: 911 Fields: Translation: HumansCells
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Remembering Ralph Steinman. J Exp Med. 2011 Nov 21; 208(12):2343-7.
Banchereau J, Cohn F, Inaba K, Muller B, Mellman I, Nathan C, Nussenzweig M, O'Garra A, Seder B, Schuler G, Sher A. PMID: 22216461.
View in: PubMed Mentions: 1 Fields: Translation: Cells
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Retrospective. Ralph M. Steinman (1943-2011). Science. 2011 Oct 28; 334(6055):466.
Mellman I, Nussenzweig M. PMID: 22034425.
View in: PubMed Mentions: 8 Fields: Translation: Cells
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Ralph Steinman (1943-2011). Nature. 2011 Oct 26; 478(7370):460.
Nussenzweig MC, Mellman I. PMID: 22031432.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. J Cell Biol. 2011 Apr 04; 193(1):219-33.
Francis SS, Sfakianos J, Lo B, Mellman I. PMID: 21444686.
View in: PubMed Mentions: 55 Fields: Translation: HumansAnimalsCells
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AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3ß (GSK-3ß) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane. J Biol Chem. 2011 May 13; 286(19):16879-90.
Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. PMID: 21383016.
View in: PubMed Mentions: 26 Fields: Translation: AnimalsCells
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Harnessing dendritic cells for immunotherapy. Semin Immunol. 2011 Feb; 23(1):2-11.
Delamarre L, Mellman I. PMID: 21377379.
View in: PubMed Mentions: 25 Fields: Translation: HumansAnimalsCells
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Cell biology redux. Mol Biol Cell. 2010 Nov 15; 21(22):3809-10.
Mellman I. PMID: 21079023.
View in: PubMed Mentions: Fields: Translation: Humans
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Designing vaccines based on biology of human dendritic cell subsets. Immunity. 2010 Oct 29; 33(4):464-78.
Palucka K, Banchereau J, Mellman I. PMID: 21029958.
View in: PubMed Mentions: 106 Fields: Translation: HumansCells
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Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly. Biochem Biophys Res Commun. 2010 Sep 17; 400(2):271-7.
Togawa A, Sfakianos J, Ishibe S, Suzuki S, Fujigaki Y, Kitagawa M, Mellman I, Cantley LG. PMID: 20728428.
View in: PubMed Mentions: 5 Fields: Translation: HumansAnimalsCells
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Immunology. Beta-catenin balances immunity. Science. 2010 Aug 13; 329(5993):767-9.
Mellman I, Clausen BE. PMID: 20705838.
View in: PubMed Mentions: 8 Fields: Translation: HumansAnimalsCells
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Monocyte-derived dendritic cells exhibit increased levels of lysosomal proteolysis as compared to other human dendritic cell populations. PLoS One. 2010 Aug 02; 5(8):e11949.
McCurley N, Mellman I. PMID: 20689855.
View in: PubMed Mentions: 23 Fields: Translation: HumansAnimalsCells
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Trafficking guidance receptors. Cold Spring Harb Perspect Biol. 2010 Jul; 2(7):a001826.
Winckler B, Mellman I. PMID: 20504966.
View in: PubMed Mentions: 28 Fields: Translation: Cells
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Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature. 2010 Apr 01; 464(7289):783-7.
Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. PMID: 20208517.
View in: PubMed Mentions: 209 Fields: Translation: HumansAnimalsCells
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Antigen processing and presentation. Curr Opin Immunol. 2010 Feb; 22(1):78-80.
Mellman I, Cresswell P. PMID: 20172702.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
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Mature dendritic cells use endocytic receptors to capture and present antigens. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4287-92.
Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L. PMID: 20142498.
View in: PubMed Mentions: 89 Fields: Translation: AnimalsCells
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Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell. 2010 Jan 19; 18(1):39-51.
Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML. PMID: 20152176.
View in: PubMed Mentions: 114 Fields: Translation: AnimalsCells
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The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res. 2009 Sep 01; 15(17):5323-37.
Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, Mellman I, Prindiville SA, Viner JL, Weiner LM, Matrisian LM. PMID: 19723653.
View in: PubMed Mentions: 440 Fields: Translation: Humans
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Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. J Cell Biol. 2009 Jul 27; 186(2):269-82.
Farr GA, Hull M, Mellman I, Caplan MJ. PMID: 19620635.
View in: PubMed Mentions: 43 Fields: Translation: HumansAnimalsCells
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Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine. 2009 May 18; 27(23):3013-21.
Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. PMID: 19428913.
View in: PubMed Mentions: 100 Fields: Translation: AnimalsCellsPHPublic Health
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Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells. Immunobiology. 2009; 214(7):495-505.
Becker SM, Delamarre L, Mellman I, Andrews NW. PMID: 19157638.
View in: PubMed Mentions: 13 Fields: Translation: AnimalsCells
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Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol. 2009 Jan 26; 184(2):281-96.
Mao YS, Yamaga M, Zhu X, Wei Y, Sun HQ, Wang J, Yun M, Wang Y, Di Paolo G, Bennett M, Mellman I, Abrams CS, De Camilli P, Lu CY, Yin HL. PMID: 19153220.
View in: PubMed Mentions: 38 Fields: Translation: HumansAnimalsCells
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Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med. 2009 Feb 16; 206(2):399-410.
Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. PMID: 19153244.
View in: PubMed Mentions: 63 Fields: Translation: AnimalsCells
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By the scientists, for the scientists. J Cell Biol. 2009 Jan 12; 184(1):7-9.
Mellman I. PMID: 19139258.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Coordinated protein sorting, targeting and distribution in polarized cells. Nat Rev Mol Cell Biol. 2008 Nov; 9(11):833-45.
Mellman I, Nelson WJ. PMID: 18946473.
View in: PubMed Mentions: 225 Fields: Translation: HumansAnimalsCells
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A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells. Traffic. 2008 Nov; 9(11):1915-24.
Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. PMID: 18764819.
View in: PubMed Mentions: 18 Fields: Translation: AnimalsCells
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A33 antigen displays persistent surface expression. Cancer Immunol Immunother. 2008 Jul; 57(7):1017-27.
Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD. PMID: 18236042.
View in: PubMed Mentions: 26 Fields: Translation: HumansCells
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Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond). 2008 Jun; 3(3):343-55.
Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. PMID: 18510429.
View in: PubMed Mentions: 16 Fields:
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Spinophilin participates in information transfer at immunological synapses. J Cell Biol. 2008 Apr 21; 181(2):203-11.
Bloom O, Unternaehrer JJ, Jiang A, Shin JS, Delamarre L, Allen P, Mellman I. PMID: 18411312.
View in: PubMed Mentions: 16 Fields: Translation: AnimalsCells
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Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol. 2008 May; 9(5):551-7.
Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, Xue Y, Mellman I, Banchereau J, Connolly JE. PMID: 18376401.
View in: PubMed Mentions: 129 Fields: Translation: HumansCells
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Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cell Microbiol. 2008 May; 10(5):1190-207.
Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, Flavell RA, Mellman I, van der Goot FG. PMID: 18194483.
View in: PubMed Mentions: 13 Fields: Translation: AnimalsCells
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Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol. 2007 Dec 17; 179(6):1133-40.
Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L, Toomre D, Mellman I. PMID: 18070914.
View in: PubMed Mentions: 53 Fields: Translation: HumansAnimalsCells
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Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody. Neoplasia. 2007 Dec; 9(12):1099-110.
Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. PMID: 18084617.
View in: PubMed Mentions: 28 Fields: Translation: HumansAnimalsCells
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Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity. 2007 Oct; 27(4):610-24.
Jiang A, Bloom O, Ono S, Cui W, Unternaehrer J, Jiang S, Whitney JA, Connolly J, Banchereau J, Mellman I. PMID: 17936032.
View in: PubMed Mentions: 137 Fields: Translation: HumansAnimalsCells
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Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007 Oct 04; 449(7162):564-9.
Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, Homey B, Cao W, Wang YH, Su B, Nestle FO, Zal T, Mellman I, Schröder JM, Liu YJ, Gilliet M. PMID: 17873860.
View in: PubMed Mentions: 533 Fields: Translation: HumansCells
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Private lives: reflections and challenges in understanding the cell biology of the immune system. Science. 2007 Aug 03; 317(5838):625-7.
Mellman I. PMID: 17673653.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
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How the rich get richer. J Exp Med. 2007 Jul 09; 204(7):1503.
Rossner M, Mellman I. PMID: 17576780.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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How the rich get richer. J Cell Biol. 2007 Jun 18; 177(6):951.
Rossner M, Mellman I. PMID: 17562793.
View in: PubMed Mentions: 2 Fields:
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Ira Mellman: from endosomes to industry. Interview by William A Wells. J Cell Biol. 2007 May 21; 177(4):570-1.
Mellman I. PMID: 17517958.
View in: PubMed Mentions: 1 Fields: Translation: HumansAnimalsCells
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Incomplete screening? Nat Immunol. 2007 May; 8(5):473.
Mellman I. PMID: 17440454.
View in: PubMed Mentions: Fields:
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The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proc Natl Acad Sci U S A. 2007 Jan 02; 104(1):234-9.
Unternaehrer JJ, Chow A, Pypaert M, Inaba K, Mellman I. PMID: 17190803.
View in: PubMed Mentions: 37 Fields: Translation: AnimalsCells
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Bringing science to cancer therapy. Yale J Biol Med. 2006 Dec; 79(3-4):177-8.
Mellman I. PMID: 17940629.
View in: PubMed Mentions: Fields: Translation: Humans
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Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic. 2007 Jan; 8(1):47-60.
Schuck S, Gerl MJ, Ang A, Manninen A, Keller P, Mellman I, Simons K. PMID: 17132146.
View in: PubMed Mentions: 57 Fields: Translation: HumansAnimalsCells
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Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature. 2006 Nov 02; 444(7115):115-8.
Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. PMID: 17051151.
View in: PubMed Mentions: 104 Fields: Translation: AnimalsCells
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Modulation of cell adhesion and motility in the immune system by Myo1f. Science. 2006 Oct 06; 314(5796):136-9.
Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA. PMID: 17023661.
View in: PubMed Mentions: 34 Fields: Translation: AnimalsCells
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Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. J Exp Med. 2006 Sep 04; 203(9):2049-55.
Delamarre L, Couture R, Mellman I, Trombetta ES. PMID: 16908625.
View in: PubMed Mentions: 68 Fields: Translation: AnimalsCells
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Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging. J Cell Biol. 2006 Mar 27; 172(7):1035-44.
Hua W, Sheff D, Toomre D, Mellman I. PMID: 16567501.
View in: PubMed Mentions: 21 Fields: Translation: AnimalsCells
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CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol. 2006 Mar 27; 172(7):1045-56.
Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S. PMID: 16567502.
View in: PubMed Mentions: 38 Fields: Translation: AnimalsCells
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Presentation of self-antigens on MHC class II molecules during dendritic cell maturation. Int Immunol. 2006 Jan; 18(1):199-209.
Zwickey HL, Unternaehrer JJ, Mellman I. PMID: 16361313.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
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Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 2005 Oct 07; 123(1):157-70.
Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, Mellman I, Grinstein S. PMID: 16213220.
View in: PubMed Mentions: 94 Fields: Translation: AnimalsCells
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Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. J Cell Biol. 2005 Aug 15; 170(4):595-605.
Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I. PMID: 16087710.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
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Targeting antigen to CD19 on B cells efficiently activates T cells. Int Immunol. 2005 Jul; 17(7):869-77.
Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ. PMID: 15967786.
View in: PubMed Mentions: 9 Fields: Translation: AnimalsCells
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The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor. FASEB J. 2005 May; 19(7):780-2.
Johns TG, Mellman I, Cartwright GA, Ritter G, Old LJ, Burgess AW, Scott AM. PMID: 15774576.
View in: PubMed Mentions: 26 Fields: Translation: HumansCells
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Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science. 2005 Mar 11; 307(5715):1630-4.
Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. PMID: 15761154.
View in: PubMed Mentions: 270 Fields: Translation: AnimalsCells
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Old lysosomes, new tricks: MHC II dynamics in DCs. Trends Immunol. 2005 Feb; 26(2):72-8.
Chow AY, Mellman I. PMID: 15668121.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
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Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol. 2005; 23:975-1028.
Trombetta ES, Mellman I. PMID: 15771591.
View in: PubMed Mentions: 360 Fields: Translation: HumansAnimalsCells
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Antigen processing and presentation by dendritic cells: cell biological mechanisms. Adv Exp Med Biol. 2005; 560:63-7.
Mellman I. PMID: 15932021.
View in: PubMed Mentions: 12 Fields: Translation: HumansAnimalsCells
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Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. J Immunol. 2004 Nov 15; 173(10):6119-24.
Meyer zum Bueschenfelde CO, Unternaehrer J, Mellman I, Bottomly K. PMID: 15528348.
View in: PubMed Mentions: 11 Fields: Translation: AnimalsCells
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Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells. J Cell Biol. 2004 Nov 08; 167(3):531-43.
Ang AL, Taguchi T, Francis S, Fölsch H, Murrells LJ, Pypaert M, Warren G, Mellman I. PMID: 15534004.
View in: PubMed Mentions: 172 Fields: Translation: AnimalsCells
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IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14467-72.
Matsuo M, Nagata Y, Sato E, Atanackovic D, Valmori D, Chen YT, Ritter G, Mellman I, Old LJ, Gnjatic S. PMID: 15383663.
View in: PubMed Mentions: 11 Fields: Translation: HumansCells
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The JEM and the JCB: a synergistic partnership. J Cell Biol. 2004 Aug 30; 166(5):611.
Steinman RM, Mellman I. PMID: 15337771.
View in: PubMed Mentions: Fields:
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Immunotherapy: bewitched, bothered, and bewildered no more. Science. 2004 Jul 09; 305(5681):197-200.
Steinman RM, Mellman I. PMID: 15247468.
View in: PubMed Mentions: 43 Fields: Translation: HumansAnimalsCells
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Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic. 2004 Jun; 5(6):449-61.
Duffield A, Fölsch H, Mellman I, Caplan MJ. PMID: 15117319.
View in: PubMed Mentions: 9 Fields: Translation: AnimalsCells
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The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. J Cell Biol. 2004 Mar 29; 164(7):1055-64.
Chang HC, Hull M, Mellman I. PMID: 15051737.
View in: PubMed Mentions: 33 Fields: Translation: AnimalsCells
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Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol. 2004 Feb; 6(2):106-12.
Yeaman C, Ayala MI, Wright JR, Bard F, Bossard C, Ang A, Maeda Y, Seufferlein T, Mellman I, Nelson WJ, Malhotra V. PMID: 14743217.
View in: PubMed Mentions: 95 Fields: Translation: HumansAnimalsCells
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The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. J Cell Biol. 2003 Oct 27; 163(2):339-50.
Ang AL, Fölsch H, Koivisto UM, Pypaert M, Mellman I. PMID: 14581456.
View in: PubMed Mentions: 91 Fields: Translation: AnimalsCells
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The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains. J Cell Biol. 2003 Oct 27; 163(2):351-62.
Fölsch H, Pypaert M, Maday S, Pelletier L, Mellman I. PMID: 14581457.
View in: PubMed Mentions: 109 Fields: Translation: HumansAnimalsCells
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Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation. J Exp Med. 2003 Jul 07; 198(1):111-22.
Delamarre L, Holcombe H, Mellman I. PMID: 12835477.
View in: PubMed Mentions: 74 Fields: Translation: AnimalsCells
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Computational cell biology. J Cell Biol. 2003 May 12; 161(3):463-4.
Mellman I, Misteli T. PMID: 12743098.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimals
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Activation of lysosomal function during dendritic cell maturation. Science. 2003 Feb 28; 299(5611):1400-3.
Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I. PMID: 12610307.
View in: PubMed Mentions: 200 Fields: Translation: AnimalsCells
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Hsc70 is required for endocytosis and clathrin function in Drosophila. J Cell Biol. 2002 Nov 11; 159(3):477-87.
Chang HC, Newmyer SL, Hull MJ, Ebersold M, Schmid SL, Mellman I. PMID: 12427870.
View in: PubMed Mentions: 39 Fields: Translation: AnimalsCells
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The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation. J Immunol. 2002 Nov 01; 169(9):4982-9.
Holcombe H, Mellman I, Janeway CA, Bottomly K, Dittel BN. PMID: 12391212.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
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Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 2002 Aug 29; 418(6901):988-94.
Chow A, Toomre D, Garrett W, Mellman I. PMID: 12198549.
View in: PubMed Mentions: 115 Fields: Translation: AnimalsCells
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Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10629-34.
Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett W, Old LJ, Mellman I. PMID: 12138174.
View in: PubMed Mentions: 22 Fields: Translation: HumansCells
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Regulation and functional insights in cellular polarity, Madrid, Spain June 3-5, 2002. J Cell Biol. 2002 Jul 08; 158(1):12-6.
Mellman I, Ridley A. PMID: 12141270.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
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Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells. Mol Biol Cell. 2002 Jul; 13(7):2374-82.
Sugimoto H, Sugahara M, Fölsch H, Koide Y, Nakatsu F, Tanaka N, Nishimura T, Furukawa M, Mullins C, Nakamura N, Mellman I, Ohno H. PMID: 12134076.
View in: PubMed Mentions: 22 Fields: Translation: HumansAnimalsCells
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Transferrin receptor recycling in the absence of perinuclear recycling endosomes. J Cell Biol. 2002 Mar 04; 156(5):797-804.
Sheff D, Pelletier L, O'Connell CB, Warren G, Mellman I. PMID: 11877458.
View in: PubMed Mentions: 40 Fields: Translation: HumansAnimalsCells
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Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes. Mol Biol Cell. 2002 Jan; 13(1):262-75.
Sheff DR, Kroschewski R, Mellman I. PMID: 11809838.
View in: PubMed Mentions: 28 Fields: Translation: AnimalsCells
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Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor. J Cell Biol. 1985 May; 100(5):1515-21.
Horwich AL, Fenton WA, Firgaira FA, Fox JE, Kolansky D, Mellman IS, Rosenberg LE. PMID: 3988798.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
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Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis. J Cell Biol. 1983 Mar; 96(3):887-95.
Mellman IS, Plutner H, Steinman RM, Unkeless JC, Cohn ZA. PMID: 6833386.
View in: PubMed Mentions: 53 Fields: Translation: AnimalsCells
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Endocytosis and the recycling of plasma membrane. J Cell Biol. 1983 Jan; 96(1):1-27.
Steinman RM, Mellman IS, Muller WA, Cohn ZA. PMID: 6298247.
View in: PubMed Mentions: 357 Fields: Translation: AnimalsCells
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Interferon action: effects of mouse alpha and beta interferons on rosette formation, phagocytosis, and surface-antigen expression of cells of the macrophage-type line RAW 309Cr.1. Cell Immunol. 1982 Oct; 73(1):128-40.
Yoshie O, Mellman IS, Broeze RJ, Garcia-Blanco M, Lengyel P. PMID: 6185239.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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Endocytosis, membrane recycling and Fc receptor function. Ciba Found Symp. 1982; (92):35-58.
Mellman IS. PMID: 6924894.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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Structural Aspects and Heterogeneity of Immunoglobulin Fc Receptors. Adv Immunol. 1981; 31:247-70.
Unkeless JC, Fleit H, Mellman IS. PMID: 7032255.
View in: PubMed Mentions: 72 Fields: Translation: AnimalsCells
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Transmembrane transport of cobalamin in prokaryotic and eukaryotic cells. Annu Rev Biochem. 1981; 50:1053-86.
Sennett C, Rosenberg LE, Mellman IS. PMID: 6267986.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimalsCells
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Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages. J Exp Med. 1980 Nov 01; 152(5):1248-61.
Steinman RM, Nogueira N, Witmer MD, Tydings JD, Mellman IS. PMID: 6448907.
View in: PubMed Mentions: 77 Fields: Translation: AnimalsCells
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Purificaton of a functional mouse Fc receptor through the use of a monoclonal antibody. J Exp Med. 1980 Oct 01; 152(4):1048-69.
Mellman IS, Unkeless JC. PMID: 6158545.
View in: PubMed Mentions: 42 Fields: Translation: HumansAnimalsCells
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Selective iodination and polypeptide composition of pinocytic vesicles. J Cell Biol. 1980 Sep; 86(3):712-22.
Mellman IS, Steinman RM, Unkeless JC, Cohn ZA. PMID: 7410475.
View in: PubMed Mentions: 40 Fields: Translation: AnimalsCells
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Protein mediated vitamin uptake. Adsorptive endocytosis of the transcobalamin II-cobalamin complex by cultured human fibroblasts. Exp Cell Res. 1979 Jan; 118(1):127-34.
Youngdahl-Turner P, Mellman IS, Allen RH, Rosenberg LE. PMID: 759210.
View in: PubMed Mentions: 14 Fields: Translation: Cells
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Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1. Proc Natl Acad Sci U S A. 1979 Jan; 76(1):405-9.
Mellman IS, Lin PF, Ruddle FH, Rosenberg LE. PMID: 284356.
View in: PubMed Mentions: 4 Fields: Translation: HumansCells
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Genetic complementation among inherited deficiencies of methylmalonyl-CoA mutase activity: evidence for a new class of human cobalamin mutant. Am J Hum Genet. 1978 Jan; 30(1):1-13.
Willard HF, Mellman IS, Rosenberg LE. PMID: 23678.
View in: PubMed Mentions: 35 Fields: Translation: HumansCells
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The chemical composition of the cell wall of Chlamydomonas gymnogama and the concept of a plant cell wall protein. J Cell Biol. 1974 Nov; 63(2 Pt 1):420-9.
Miller DH, Mellman IS, Lamport DT, Miller M. PMID: 4607708.
View in: PubMed Mentions: 23 Fields: Translation: AnimalsCells
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Year | Publications |
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2002 | 8 | 2003 | 5 | 2004 | 8 | 2005 | 9 | 2006 | 8 | 2007 | 9 | 2008 | 7 | 2009 | 7 | 2010 | 10 | 2011 | 7 | 2012 | 6 | 2013 | 9 | 2014 | 3 | 2015 | 8 | 2016 | 8 | 2017 | 6 | 2018 | 5 | 2019 | 4 | 2020 | 5 | 2021 | 1 |
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This graph shows the number and percent of publications by field.
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Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
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