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Matthew Hirschtritt, MD, MPH

Title(s)Clinical Fellow, Psychiatry
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Cornell University, Ithaca, NYBA05/2005Psychology
    Cleveland Clinic Lerner College of Medicine, Cleveland, OHMD06/2014
    Case Western Reserve University, Cleveland, OHMPH05/2014Population Health
    University of California, San Francisco, San Francisco, CA06/2018Adult Psychiatry Residency
    University of California, San Francisco, San Francisco, CA06/2019Forensic Psychiatry Fellowship
    Collapse Awards and Honors
    Cornell University2001  - 2005Pauline and Irving Tanner Dean’s Scholar
    Cornell University2004  - 2005Cornell Tradition Fellow
    Ohio Psychiatric Physicians Foundation2012  - 2012Medical Student Research Award
    Mental Health Section of the American Public Health Association2013  - 2013Ken Lutterman Student Research Award
    Cleveland Clinic Foundation2014  - 2014Excellence in Psychiatry
    NNCI2016  - 2017National Neuroscience Curriculum Initiative (NNCI) Scholar
    Society of Biological Psychiatry2017  - 2017Travel Fellowship Award
    American Academy of Psychiatry and the Law2017  - 2018Rappeport Fellowship
    University of California, San Francisco2018  - 2018Psychiatry Trainee Research Award
    University of Pittsburgh2018  - 2020Career Development Institute for Psychiatry
    American College of Neuropsychopharmacology2018  - 2018Travel Award

    Collapse Overview 
    Collapse Overview
    Dr. Hirschtritt is a Forensic Psychiatry Clinical Fellow and researcher in the UCSF Department of Psychiatry and the UCSF Weill Institute for Neurosciences. The overarching goals of his research include improving equitable access to, quality of, and cost-effectiveness of mental health detection and treatment, focusing on under-served and marginalized communities.

    Dr. Hirschtritt's investigative work has involved diverse mental health-related topics, including characteristics and treatments for obsessive-compulsive disorder, Tourette syndrome, adolescent depression and attention-deficit/hyperactivity disorder, and substance use disorders. His work has also examined the interrelationship between adolescent resiliency, peer victimization, and suicidal ideation. More recently, his work has focused on the distribution, provision, and quality of mental health care in the United States, which has involved addressing mental health stigma (specifically the harmful implications of attributing gun violence exclusively to mental illness) and psychotropic prescription patterns using nationally representative data. As a member of the American Academy of Psychiatry and the Law and fellow in forensic psychiatry at UCSF (starting July 2018), Dr. Hirschtritt seeks to identify and fill gaps in care among justice-involved individuals with mental illness, a cohort that represents a particularly vulnerable and under-served population. His current research, under the mentorship of UCSF and Zuckerberg San Francisco General Hospital principal investigator Marina Tolou-Shams, PhD, explores the mental health and risk-behavior trajectories of court-involved, sexual minority adolescents.

    In addition to his research experience, Dr. Hirschtritt has worked in various clinical psychiatric settings, including inpatient units in a safety-net, academically affiliated, and private hospitals, psychiatric emergency services, and outpatient services (including interdisciplinary clinics focused on the needs of sexual minority adults and young adults with new- or recent-onset psychosis). He is an enthusiastic educator, having designed an online curriculum for the National Neuroscience Curriculum Initiative and he continues to lead medical student seminars on foundational psychiatric topics.

    Following completion of his undergraduate degree in psychology from Cornell University, Dr. Hirschtritt joined the National Institute of Mental Health as an Intramural Research Training Award recipient. He then completed his pre-medical, postbaccalaureate coursework at Johns Hopkins University, and, before beginning medical school, served as a research associate in the Yale Child Study Center. As a student in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, a five-year program dedicated to training clinician-scientists, Dr. Hirschtritt completed additional coursework in public health (leading to an MPH degree), and first came to UCSF as a Doris Duke Clinical Scholar, where he has stayed for his residency (completed in June 2018) and clinical fellowship (anticipated completion in June 2019).

    Collapse Research 
    Collapse Research Activities and Funding
    Training The Next Generation of Mental Health Researchers
    NIH 5R25MH060482-17Jul 23, 2000 - Jun 30, 2021
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse In The News
    Collapse Twitter
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Luðvigsson P, Sæmundsen E, Thorarensen Ó, Atzmon G, Barzilai N, Wagner M, Moessner R, Ophoff R, Pato CN, Pato MT, Knowles JA, Roffman JL, Smoller JW, Buckner RL, Willsey AJ, Tischfield JA, Heiman GA, Stefansson H, Stefansson K, Posthuma D, Cox NJ, Pauls DL, Freimer NB, Neale BM, Davis LK, Paschou P, Coppola G, Mathews CA, Scharf JM. Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. Am J Psychiatry. 2019 Mar 01; 176(3):217-227. PMID: 30818990.
      View in: PubMed
    2. Tolou-Shams M, Harrison A, Hirschtritt ME, Dauria E, Barr-Walker J. Substance Use and HIV Among Justice-Involved Youth: Intersecting Risks. Curr HIV/AIDS Rep. 2019 Feb 08. PMID: 30734906.
      View in: PubMed
    3. Hirschtritt ME, Noy G, Haller E, Forstein M. LGBT-Specific Education in General Psychiatry Residency Programs: a Survey of Program Directors. Acad Psychiatry. 2018 Nov 14. PMID: 30430392.
      View in: PubMed
    4. Hirschtritt ME, Carroll JD, Ross DA. Using Neuroscience to Make Sense of Psychopathy. Biol Psychiatry. 2018 Nov 01; 84(9):e61-e63. PMID: 30297023.
      View in: PubMed
    5. Hirschtritt ME, Kline-Simon AH, Kroenke K, Sterling SA. Depression Screening Rates and Symptom Severity by Alcohol Use Among Primary Care Adult Patients. J Am Board Fam Med. 2018 Sep-Oct; 31(5):724-732. PMID: 30201668.
      View in: PubMed
    6. Hirschtritt ME, Dauria EF, Marshall BDL, Tolou-Shams M. Sexual Minority, Justice-Involved Youth: A Hidden Population in Need of Integrated Mental Health, Substance Use, and Sexual Health Services. J Adolesc Health. 2018 Oct; 63(4):421-428. PMID: 30077548.
      View in: PubMed
    7. Hirschtritt, M.E., Insel, T.R.Digital technologies in psychiatry: present and future. Focus: The Journal of Lifelong Learning in Psychiatry. 2018; 16(3):251-258.
    8. Hirschtritt ME, Heaton PM, Insel TR. Preparing Physician-Scientists for an Evolving Research Ecosystem. JAMA. 2018 Jul 03; 320(1):31-32. PMID: 29799967.
      View in: PubMed
    9. Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, et al. Analysis of shared heritability in common disorders of the brain. Science. 2018 06 22; 360(6395). PMID: 29930110.
      View in: PubMed
    10. Hirschtritt ME, Binder RL. A Reassessment of Blaming Mass Shootings on Mental Illness. JAMA Psychiatry. 2018 Apr 01; 75(4):311-312. PMID: 29490356.
      View in: PubMed
    11. Hirschtritt ME, Delucchi KL, Olfson M. Outpatient, combined use of opioid and benzodiazepine medications in the United States, 1993-2014. Prev Med Rep. 2018 Mar; 9:49-54. PMID: 29340270.
      View in: PubMed
    12. Hirschtritt ME, Chan S, Ly WO. Realizing E-Prescribing's Potential to Reduce Outpatient Psychiatric Medication Errors. Psychiatr Serv. 2018 Feb 01; 69(2):129-132. PMID: 29241438.
      View in: PubMed
    13. Fisher WS, Hirschtritt ME, Haller E. Development and Implementation of a Residency Area-of-Distinction in Lesbian, Gay, Bisexual, and Transgender Mental Health. Acad Psychiatry. 2018 Aug; 42(4):564-566. PMID: 29110270.
      View in: PubMed
    14. Greenberg E, Tung ES, Gauvin C, Osiecki L, Yang KG, Curley E, Essa A, Illmann C, Sandor P, Dion Y, Lyon GJ, King RA, Darrow S, Hirschtritt ME, Budman CL, Grados M, Pauls DL, Keuthen NJ, Mathews CA, Scharf JM. Prevalence and predictors of hair pulling disorder and excoriation disorder in Tourette syndrome. Eur Child Adolesc Psychiatry. 2018 May; 27(5):569-579. PMID: 29098466.
      View in: PubMed
    15. Hirschtritt ME, Kroenke K. Screening for Depression. JAMA. 2017 08 22; 318(8):745-746. PMID: 28829850.
      View in: PubMed
    16. Hirschtritt ME, Bloch MH, Mathews CA. Deep Brain Stimulation for Obsessive-Compulsive Disorder-Reply. JAMA. 2017 07 25; 318(4):393. PMID: 28742903.
      View in: PubMed
    17. Hirschtritt ME, Darrow SM, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King RA, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA. Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome. Psychol Med. 2018 Jan; 48(2):279-293. PMID: 28651666.
      View in: PubMed
    18. Huang AY, Yu D, Davis LK, Sul JH, Tsetsos F, Ramensky V, Zelaya I, Ramos EM, Osiecki L, Chen JA, McGrath LM, Illmann C, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, King RA, Dion Y, Rouleau G, Budman CL, Depienne C, Worbe Y, Hartmann A, Müller-Vahl KR, Stuhrmann M, Aschauer H, Stamenkovic M, Schloegelhofer M, Konstantinidis A, Lyon GJ, McMahon WM, Barta C, Tarnok Z, Nagy P, Batterson JR, Rizzo R, Cath DC, Wolanczyk T, Berlin C, Malaty IA, Okun MS, Woods DW, Rees E, Pato CN, Pato MT, Knowles JA, Posthuma D, Pauls DL, Cox NJ, Neale BM, Freimer NB, Paschou P, Mathews CA, Scharf JM, Coppola G. Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron. 2017 Jun 21; 94(6):1101-1111.e7. PMID: 28641109.
      View in: PubMed
    19. Darrow SM, Grados M, Sandor P, Hirschtritt ME, Illmann C, Osiecki L, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA. Autism Spectrum Symptoms in a Tourette's Disorder Sample. J Am Acad Child Adolesc Psychiatry. 2017 Jul; 56(7):610-617.e1. PMID: 28647013.
      View in: PubMed
    20. Willsey AJ, Fernandez TV, Yu D, King RA, Dietrich A, Xing J, Sanders SJ, Mandell JD, Huang AY, Richer P, Smith L, Dong S, Samocha KE, Neale BM, Coppola G, Mathews CA, Tischfield JA, Scharf JM, State MW, Heiman GA. De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron. 2017 May 03; 94(3):486-499.e9. PMID: 28472652.
      View in: PubMed
    21. Hirschtritt ME, Bloch MH, Mathews CA. Obsessive-Compulsive Disorder: Advances in Diagnosis and Treatment. JAMA. 2017 04 04; 317(13):1358-1367. PMID: 28384832.
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    22. Hirschtritt ME, Binder RL. Interrupting the Mental Illness-Incarceration-Recidivism Cycle. JAMA. 2017 Feb 21; 317(7):695-696. PMID: 28241364.
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    23. Darrow SM, Hirschtritt ME, Davis LK, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA. Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome. Am J Psychiatry. 2017 04 01; 174(4):387-396. PMID: 27809572.
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    24. Hirschtritt ME, Dy ME, Yang KG, Scharf JM. Child Neurology: Diagnosis and treatment of Tourette syndrome. Neurology. 2016 08 16; 87(7):e65-7. PMID: 27527544.
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    25. Hirschtritt ME, Besterman AD, Ross DA. Psychiatric Pharmacogenomics: How Close Are We? Biol Psychiatry. 2016 10 15; 80(8):e63-5. PMID: 27663067.
      View in: PubMed
    26. Hirschtritt ME, Darrow SM, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King RA, Pauls DL, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA. Social disinhibition is a heritable subphenotype of tics in Tourette syndrome. Neurology. 2016 Aug 02; 87(5):497-504. PMID: 27371487; PMCID: PMC4970665 [Available on 08/02/17].
    27. Hirschtritt ME, Ordóñez AE, Rico YC, LeWinn KZ. Internal resilience, peer victimization, and suicidal ideation among adolescents. Int J Adolesc Med Health. 2015 Nov; 27(4):415-23. PMID: 25719294.
      View in: PubMed
    28. Darrow SM, Illmann C, Gauvin C, Osiecki L, Egan CA, Greenberg E, Eckfield M, Hirschtritt ME, Pauls DL, Batterson JR, Berlin CM, Malaty IA, Woods DW, Scharf JM, Mathews CA. Web-based phenotyping for Tourette Syndrome: Reliability of common co-morbid diagnoses. Psychiatry Res. 2015 Aug 30; 228(3):816-25. PMID: 26054936; PMCID: PMC4532555.
    29. Hirschtritt ME, Lee PC, Pauls DL, Dion Y, Grados MA, Illmann C, King RA, Sandor P, McMahon WM, Lyon GJ, Cath DC, Kurlan R, Robertson MM, Osiecki L, Scharf JM, Mathews CA. Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome. JAMA Psychiatry. 2015 Apr; 72(4):325-33. PMID: 25671412; PMCID: PMC4446055.
    30. Peachey NS, Pearring JN, Bojang P, Hirschtritt ME, Sturgill-Short G, Ray TA, Furukawa T, Koike C, Goldberg AF, Shen Y, McCall MA, Nawy S, Nishina PM, Gregg RG. Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation. J Neurophysiol. 2012 Nov; 108(9):2442-51. PMID: 22896717; PMCID: PMC3545183.
    31. Hirschtritt ME, Pagano ME, Christian KM, McNamara NK, Stansbrey RJ, Lingler J, Faber JE, Demeter CA, Bedoya D, Findling RL. Moderators of fluoxetine treatment response for children and adolescents with comorbid depression and substance use disorders. J Subst Abuse Treat. 2012 Jun; 42(4):366-72. PMID: 22116008; PMCID: PMC3415216.
    32. Kiringoda R, Thurm AE, Hirschtritt ME, Koziol D, Wesley R, Swedo SE, O'Grady NP, Quezado ZM. Risks of propofol sedation/anesthesia for imaging studies in pediatric research: eight years of experience in a clinical research center. Arch Pediatr Adolesc Med. 2010 Jun; 164(6):554-60. PMID: 20530306.
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    33. Hirschtritt ME, Hammond CJ, Luckenbaugh D, Buhle J, Thurm AE, Casey BJ, Swedo SE. Executive and attention functioning among children in the PANDAS subgroup. Child Neuropsychol. 2009 Mar; 15(2):179-94. PMID: 18622810.
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    34. Grant P, Lougee L, Hirschtritt M, Swedo SE. An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder. J Child Adolesc Psychopharmacol. 2007 Dec; 17(6):761-7. PMID: 18315448.
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