Loading...

Joe Wiemels, PhD

Title(s)Professor, Epidemiology & Biostatistics
SchoolSchool of Medicine
Phone415-514-0577
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Kenyon CollegeBA1988Biology
    University of California BerkeleyPhD1997Environmental Health Sciences
    Institute of Cancer Research, UKPostdoctoral1999Biology of childhood leukemia

    Collapse Overview 
    Collapse Overview
    The causes of most human cancers are unclear, but appear to be related to miscues in normal tissue developmental pathways, mutations (genetic and epigenetic) in critical genes caused by errors, infection, and chemicals, and a failure of recognition and removal of tumors by the immune system. Dr. Wiemels studies these factors as potential causes of hematopoietic and brain tumors. Large population-based studies of human cancer in the San Francisco Bay Area and State of California form a basis for examining the origin of these cancers, with a focus on future prevention. This type of research is highly collaborative, and Dr. Wiemels works with several epidemiologists, geneticists, clinicians, biologists, and statisticians.

    Collapse Research 
    Collapse Research Activities and Funding
    Brain Tumor Epidemiology Consortium
    NIH/NCI R13CA206359Apr 1, 2016 - Mar 31, 2017
    Role: Principal Investigator
    Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations
    NIH/NCI R01CA194189Sep 9, 2015 - Jan 31, 2021
    Role: Principal Investigator
    Perinatal immune development and risk of childhood acute lymphoblastic leukemia
    NIH/NCI R01CA175737Aug 1, 2014 - Jul 31, 2019
    Role: Principal Investigator
    Impact of low IL-10 levels at birth and leukemia risk
    NIH/NCI R01CA185058Jun 1, 2014 - May 31, 2019
    Role: Principal Investigator
    Varicella virus antigens in glioma etiology and survival
    NIH/NCI U01CA182371Mar 6, 2014 - Jan 31, 2018
    Role: Principal Investigator
    Genome-Wide Association Study of Childhood Leukemia by Hispanic Status
    NIH/NCI R01CA155461Jul 1, 2011 - Apr 30, 2015
    Role: Principal Investigator
    Center for Integrative Research on Childhood Leukemia and the Environment
    NIH P50ES018172Sep 25, 2009 - Jun 30, 2019
    Role: Co-Investigator
    Center for Integrative Research on Childhood Leukemia and the Environment
    NIH P01ES018172Sep 25, 2009 - Jul 31, 2014
    Role: Co-Investigator
    Meningioma: Risk Factors and Quality of Life
    NIH/NCI R01CA109745Jun 26, 2006 - Apr 30, 2011
    Role: Principal Investigator
    BACKTRACKING TRANSLOCATIONS IN CHILDHOOD LEUKEMIA
    NIH/NCI R01CA089032Mar 2, 2001 - Aug 31, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. de Smith AJ, Walsh KM, Morimoto LM, Francis SS, Hansen HM, Jeon S, Gonseth S, Chen M, Sun H, Luna-Fineman S, Antillón F, Girón V, Kang AY, Smirnov I, Shao X, Whitehead TP, Barcellos LF, Jolly KW, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson PD, Pombo-de-Oliveira MS, Spector LG, DeWan AT, Mueller BA, Chiang C, Metayer C, Ma X, Wiemels JL. Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome. Leukemia. 2019 Jul 11. PMID: 31296947.
      View in: PubMed
    2. Muskens IS, Zhang C, de Smith AJ, Biegel JA, Walsh KM, Wiemels JL. Germline genetic landscape of pediatric central nervous system (CNS) tumors. Neuro Oncol. 2019 Jun 19. PMID: 31247102.
      View in: PubMed
    3. de Smith AJ, Lavoie G, Walsh KM, Aujla S, Evans E, Hansen HM, Smirnov I, Kang AY, Zenker M, Ceremsak JJ, Stieglitz E, Muskens IS, Roberts W, McKean-Cowdin R, Metayer C, Roux PP, Wiemels JL. Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children. Genes Chromosomes Cancer. 2019 May 18. PMID: 31102422.
      View in: PubMed
    4. Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAS, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin MR, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Gong YY, Richiardi L, Kogevinas M, Litonjua AA, Eskenazi B, Huen K, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli AA, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert MF, Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder EB, Davey Smith G, Jaddoe VWV, Lie RT, Nystad W, London SJ, Lawlor DA, Relton CL, Snieder H, Felix JF. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nat Commun. 2019 04 23; 10(1):1893. PMID: 31015461.
      View in: PubMed
    5. Wiemels JL, Talbäck M, Francis S, Feychting M. Early Infection with Cytomegalovirus and Risk of Childhood Hematologic Malignancies. Cancer Epidemiol Biomarkers Prev. 2019 Jun; 28(6):1024-1027. PMID: 30996022.
      View in: PubMed
    6. Nielsen AB, Zhou M, de Smith AJ, Wang R, McCoy L, Hansen H, Morimoto L, Grønbæk K, Johansen C, Kogan SC, Metayer C, Bracci PM, Ma X, Wiemels JL. Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in etiology. Haematologica. 2019 03 28. PMID: 30923090.
      View in: PubMed
    7. Eckel-Passow JE, Decker PA, Kosel ML, Kollmeyer TM, Molinaro AM, Rice T, Caron AA, Drucker KL, Praska CE, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Erickson BJ, Lucchinetti CF, Wiemels JL, Wiencke JK, Bondy ML, Melin B, Burns TC, Giannini C, Lachance DH, Wrensch MR, Jenkins RB. Using germline variants to estimate glioma and subtype risks. Neuro Oncol. 2019 Mar 18; 21(4):451-461. PMID: 30624711.
      View in: PubMed
    8. Muskens IS, Wu AH, Porcel J, Cheng I, Le Marchand L, Wiemels JL, Setiawan VW. Body mass index, comorbidities, and hormonal factors in relation to meningioma in an ethnically diverse population: the Multiethnic Cohort. Neuro Oncol. 2019 Mar 18; 21(4):498-507. PMID: 30615143.
      View in: PubMed
    9. Gonseth S, Shaw GM, Roy R, Segal MR, Asrani K, Rine J, Wiemels J, Marini NJ. Epigenomic profiling of newborns with isolated orofacial clefts reveals widespread DNA methylation changes and implicates metastable epiallele regions in disease risk. Epigenetics. 2019 Feb; 14(2):198-213. PMID: 30870065.
      View in: PubMed
    10. Muskens IS, Hansen HM, Smirnov IV, Molinaro AM, Bondy ML, Schildkraut JM, Wrensch M, Wiemels JL, Claus EB. Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk. J Neurooncol. 2019 May; 142(3):479-487. PMID: 30796745.
      View in: PubMed
    11. Takahashi H, Cornish AJ, Sud A, Law PJ, Disney-Hogg L, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Schildkraut JM, Simon M, Bondy M, Wrensch M, Wiemels JL, Claus EB, Turnbull C, Houlston RS. Mendelian randomization provides support for obesity as a risk factor for meningioma. Sci Rep. 2019 Jan 22; 9(1):309. PMID: 30670737.
      View in: PubMed
    12. Johnson KJ, Broholm H, Scheurer ME, Lau CC, Hainfellner JA, Wiemels J, Schwartzbaum J. Advancing brain tumor epidemiology - multi-level integration and international collaboration: The 2018 Brain Tumor Epidemiology Consortium meeting report. Clin Neuropathol. 2018 Nov/Dec; 37(6):254-261. PMID: 30343678.
      View in: PubMed
    13. Claus EB, Cornish AJ, Broderick P, Schildkraut JM, Dobbins SE, Holroyd A, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Swerdlow A, Larsen SB, Johansen C, Simon M, Bondy M, Wrensch M, Houlston RS, Wiemels JL. Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. Neuro Oncol. 2018 Oct 09; 20(11):1485-1493. PMID: 29762745.
      View in: PubMed
    14. de Smith AJ, Walsh KM, Francis SS, Zhang C, Hansen HM, Smirnov I, Morimoto L, Whitehead TP, Kang A, Shao X, Barcellos LF, McKean-Cowdin R, Zhang L, Fu C, Wang R, Yu H, Hoh J, Dewan AT, Metayer C, Ma X, Wiemels JL. BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia. Int J Cancer. 2018 12 01; 143(11):2647-2658. PMID: 29923177.
      View in: PubMed
    15. Søegaard SH, Rostgaard K, Skogstrand K, Wiemels JL, Schmiegelow K, Hjalgrim H. Neonatal Inflammatory Markers Are Associated with Childhood B-cell Precursor Acute Lymphoblastic Leukemia. Cancer Res. 2018 Sep 15; 78(18):5458-5463. PMID: 30217873.
      View in: PubMed
    16. Zhang C, Morimoto LM, de Smith AJ, Hansen HM, Gonzalez-Maya J, Endicott AA, Smirnov IV, Metayer C, Wei Q, Eward WC, Wiemels JL, Walsh KM. Genetic determinants of childhood and adult height associated with osteosarcoma risk. Cancer. 2018 Sep 15; 124(18):3742-3752. PMID: 30311632.
      View in: PubMed
    17. Wallace AD, Wendt GA, Barcellos LF, de Smith AJ, Walsh KM, Metayer C, Costello JF, Wiemels JL, Francis SS. To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes. Front Genet. 2018; 9:298. PMID: 30154825.
      View in: PubMed
    18. Wallace AD, Francis SS, Ma X, McKean-Cowdin R, Selvin S, Whitehead TP, Barcellos LF, Kang AY, Morimoto L, Moore TB, Wiemels JL, Metayer C. Allergies and Childhood Acute Lymphoblastic Leukemia: A Case-Control Study and Meta-analysis. Cancer Epidemiol Biomarkers Prev. 2018 Oct; 27(10):1142-1150. PMID: 30068517.
      View in: PubMed
    19. Zhang C, Wiemels JL, Hansen HM, Gonzalez-Maya J, Endicott AA, de Smith AJ, Smirnov IV, Witte JS, Morimoto LM, Metayer C, Walsh KM. Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk. Cancer Epidemiol Biomarkers Prev. 2018 Oct; 27(10):1151-1158. PMID: 30038050.
      View in: PubMed
    20. Francis SS, Wiemels JL, Yang W, Shaw GM. Herpesvirus Infection in Infants with Gastroschisis. Epidemiology. 2018 07; 29(4):571-573. PMID: 29634591.
      View in: PubMed
    21. Scheurer ME, Lupo PJ, Schüz J, Spector LG, Wiemels JL, Aplenc R, Gramatges MM, Schiffman JD, Pombo-de-Oliveira MS, Yang JJ, Heck JE, Metayer C, Orjuela-Grimm MA, Bona K, Aristizabal P, Austin MT, Rabin KR, Russell HV, Poplack DG. An overview of disparities in childhood cancer: Report on the Inaugural Symposium on Childhood Cancer Health Disparities, Houston, Texas, 2016. Pediatr Hematol Oncol. 2018 Mar; 35(2):95-110. PMID: 29737912.
      View in: PubMed
    22. Ojha J, Dyagil I, Finch SC, Reiss RF, de Smith AJ, Gonseth S, Zhou M, Hansen HM, Sherborne AL, Nakamura J, Bracci PM, Gudzenko N, Hatch M, Babkina N, Little MP, Chumak VV, Walsh KM, Bazyka D, Wiemels JL, Zablotska LB. Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers. Environ Health. 2018 05 02; 17(1):43. PMID: 29720177.
      View in: PubMed
    23. Morimoto LM, Zava D, McGlynn KA, Stanczyk FZ, Kang AY, Ma X, Wiemels JL, Metayer C. Neonatal Hormone Concentrations and Risk of Testicular Germ Cell Tumors (TGCT). Cancer Epidemiol Biomarkers Prev. 2018 04; 27(4):488-495. PMID: 29475970.
      View in: PubMed
    24. Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ. Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol. 2018 02 01; 47(1):22-23u. PMID: 29025028.
      View in: PubMed
    25. Wiemels JL, Walsh KM, de Smith AJ, Metayer C, Gonseth S, Hansen HM, Francis SS, Ojha J, Smirnov I, Barcellos L, Xiao X, Morimoto L, McKean-Cowdin R, Wang R, Yu H, Hoh J, DeWan AT, Ma X. GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. Nat Commun. 2018 01 18; 9(1):286. PMID: 29348612.
      View in: PubMed
    26. Johnson KJ, Schwartzbaum J, Kruchko C, Scheurer ME, Lau CC, Woehrer A, Hainfellner JA, Wiemels J. Brain tumor epidemiology in the era of precision medicine: The 2017 Brain Tumor Epidemiology Consortium meeting report. Clin Neuropathol. 2017 Nov/Dec; 36(6):255-263. PMID: 29035190.
      View in: PubMed
    27. Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, Bohlin J, Xu Z, Huang RC, Reese SE, Xu CJ, Baïz N, Hoyo C, Agha G, Roy R, Holloway JW, Ghantous A, Merid SK, Bakulski KM, Küpers LK, Zhang H, Richmond RC, Page CM, Duijts L, Lie RT, Melton PE, Vonk JM, Nohr EA, Williams-DeVane C, Huen K, Rifas-Shiman SL, Ruiz-Arenas C, Gonseth S, Rezwan FI, Herceg Z, Ekström S, Croen L, Falahi F, Perron P, Karagas MR, Quraishi BM, Suderman M, Magnus MC, Jaddoe VWV, Taylor JA, Anderson D, Zhao S, Smit HA, Josey MJ, Bradman A, Baccarelli AA, Bustamante M, Håberg SE, Pershagen G, Hertz-Picciotto I, Newschaffer C, Corpeleijn E, Bouchard L, Lawlor DA, Maguire RL, Barcellos LF, Davey Smith G, Eskenazi B, Karmaus W, Marsit CJ, Hivert MF, Snieder H, Fallin MD, Melén E, Munthe-Kaas MC, Arshad H, Wiemels JL, Annesi-Maesano I, Vrijheid M, Oken E, Holland N, Murphy SK, Sørensen TIA, Koppelman GH, Newnham JP, Wilcox AJ, Nystad W, London SJ, Felix JF, Relton CL. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium. Hum Mol Genet. 2017 10 15; 26(20):4067-4085. PMID: 29016858.
      View in: PubMed
    28. Wallace AD, Francis SS, Shao X, de Smith AJ, Walsh KM, Mckean-Cowdin R, Ma X, Dahl G, Barcellos LF, Wiemels JL, Metayer C. A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology. Haematologica. 2018 Jan; 103(1):e29-e31. PMID: 29025908.
      View in: PubMed
    29. Wang R, Metayer C, Morimoto L, Wiemels JL, Yang J, DeWan AT, Kang A, Ma X. Parental Age and Risk of Pediatric Cancer in the Offspring: A Population-Based Record-Linkage Study in California. Am J Epidemiol. 2017 Oct 01; 186(7):843-856. PMID: 28535175.
      View in: PubMed
    30. Benz LS, Wrensch MR, Schildkraut JM, Bondy ML, Warren JL, Wiemels JL, Claus EB. Quality of life after surgery for intracranial meningioma. Cancer. 2018 Jan 01; 124(1):161-166. PMID: 28902404.
      View in: PubMed
    31. Zhang C, de Smith AJ, Smirnov IV, Wiencke JK, Wiemels JL, Witte JS, Walsh KM. Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma. J Neurooncol. 2017 Nov; 135(2):237-244. PMID: 28721485.
      View in: PubMed
    32. Bazyka D, Finch SC, Ilienko IM, Lyaskivska O, Dyagil I, Trotsiuk N, Gudzenko N, Chumak VV, Walsh KM, Wiemels J, Little MP, Zablotska LB. Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures. Environ Health. 2017 06 23; 16(1):70. PMID: 28645274.
      View in: PubMed
    33. Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Freeland DM, Miller R, Murphy SK. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. Environ Health Perspect. 2017 04; 125(4):511-526. PMID: 28362264.
      View in: PubMed
    34. Pekmezci M, Rice T, Molinaro AM, Walsh KM, Decker PA, Hansen H, Sicotte H, Kollmeyer TM, McCoy LS, Sarkar G, Perry A, Giannini C, Tihan T, Berger MS, Wiemels JL, Bracci PM, Eckel-Passow JE, Lachance DH, Clarke J, Taylor JW, Luks T, Wiencke JK, Jenkins RB, Wrensch MR. Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT. Acta Neuropathol. 2017 06; 133(6):1001-1016. PMID: 28255664.
      View in: PubMed
    35. de Smith AJ, Kaur M, Gonseth S, Endicott A, Selvin S, Zhang L, Roy R, Shao X, Hansen HM, Kang AY, Walsh KM, Dahl GV, McKean-Cowdin R, Metayer C, Wiemels JL. Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia. Cancer Res. 2017 04 01; 77(7):1674-1683. PMID: 28202519.
      View in: PubMed
    36. Wiencke JK, Koestler DC, Salas LA, Wiemels JL, Roy RP, Hansen HM, Rice T, McCoy LS, Bracci PM, Molinaro AM, Kelsey KT, Wrensch MR, Christensen BC. Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival. Clin Epigenetics. 2017; 9:10. PMID: 28184256.
      View in: PubMed
    37. Wang R, Wiemels JL, Metayer C, Morimoto L, Francis SS, Kadan-Lottick N, DeWan AT, Zhang Y, Ma X. Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California. Am J Epidemiol. 2017 01 15; 185(2):96-105. PMID: 27986703.
      View in: PubMed
    38. Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL. In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood. 2017 03 23; 129(12):1680-1684. PMID: 27979823.
      View in: PubMed
    39. Barrington-Trimis JL, Cockburn M, Metayer C, Gauderman WJ, Wiemels J, McKean-Cowdin R. Trends in childhood leukemia incidence over two decades from 1992 to 2013. Int J Cancer. 2017 Mar 01; 140(5):1000-1008. PMID: 27778348.
      View in: PubMed
    40. Endicott AA, Morimoto LM, Kline CN, Wiemels JL, Metayer C, Walsh KM. Perinatal factors associated with clinical presentation of osteosarcoma in children and adolescents. Pediatr Blood Cancer. 2017 06; 64(6). PMID: 27860191.
      View in: PubMed
    41. de Smith AJ, Ojha J, Francis SS, Sanders E, Endicott AA, Hansen HM, Smirnov I, Termuhlen AM, Walsh KM, Metayer C, Wiemels JL. Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia. Oncotarget. 2016 Nov 08; 7(45):72733-72745. PMID: 27683039.
      View in: PubMed
    42. Kaur M, de Smith AJ, Selvin S, Zhang L, Cunningham M, Kang MW, Hansen HM, Cooper RM, McKean-Cowdin R, Wiemels JL, Metayer C. Tobacco Smoke and Ras Mutations Among Latino and Non-Latino Children with Acute Lymphoblastic Leukemia. Arch Med Res. 2016 11; 47(8):677-683. PMID: 28476195.
      View in: PubMed
    43. Triebwasser C, Wang R, DeWan AT, Metayer C, Morimoto L, Wiemels JL, Kadan-Lottick N, Ma X. Birth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California. Eur J Cancer. 2016 12; 69:19-27. PMID: 27814470.
      View in: PubMed
    44. Metayer C, Dahl G, Wiemels J, Miller M. Childhood Leukemia: A Preventable Disease. Pediatrics. 2016 Nov; 138(Suppl 1):S45-S55. PMID: 27940977.
      View in: PubMed
    45. Whitehead TP, Metayer C, Wiemels JL, Singer AW, Miller MD. Childhood Leukemia and Primary Prevention. Curr Probl Pediatr Adolesc Health Care. 2016 Oct; 46(10):317-352. PMID: 27968954.
      View in: PubMed
    46. Johnson KJ, Hainfellner JA, Lau CC, Scheurer ME, Woehrer A, Wiemels J. Immune factors and viral interactions in brain cancer etiology and outcomes, The 2016 Brain Tumor Epidemiology Consortium Meeting report. Clin Neuropathol. 2016 Sep-Oct; 35(5):280-6. PMID: 27546018.
      View in: PubMed
    47. Gonseth S, de Smith AJ, Roy R, Zhou M, Lee ST, Shao X, Ohja J, Wrensch MR, Walsh KM, Metayer C, Wiemels JL. Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates. Epigenetics. 2016 09; 11(9):664-673. PMID: 27403598.
      View in: PubMed
    48. Sapru A, Liu KD, Wiemels J, Hansen H, Pawlikowska L, Poon A, Jorgenson E, Witte JS, Calfee CS, Ware LB, Matthay MA. Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome. Crit Care. 2016 May 23; 20(1):151. PMID: 27215212; PMCID: PMC4876559.
      View in: PubMed, PubMed Central
    49. Ojha J, Codd V, Nelson CP, Samani NJ, Smirnov IV, Madsen NR, Hansen HM, de Smith AJ, Bracci PM, Wiencke JK, Wrensch MR, Wiemels JL, Walsh KM. Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia. Cancer Epidemiol Biomarkers Prev. 2016 07; 25(7):1043-9. PMID: 27197291; PMCID: PMC5008454 [Available on 07/01/17].
      View in: PubMed, PubMed Central
    50. Walsh KM, Whitehead TP, de Smith AJ, Smirnov IV, Park M, Endicott AA, Francis SS, Codd V, Samani NJ, Metayer C, Wiemels JL. Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. Carcinogenesis. 2016 06; 37(6):576-582. PMID: 27207662.
      View in: PubMed
    51. Hsu LI, Briggs F, Shao X, Metayer C, Wiemels JL, Chokkalingam AP, Barcellos LF. Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics. Cancer Epidemiol Biomarkers Prev. 2016 05; 25(5):815-22. PMID: 26941364; PMCID: PMC4873450 [Available on 05/01/17].
      View in: PubMed, PubMed Central
    52. Wiemels J, Ma X. Stressful exit from the womb and risk of childhood leukaemia. Lancet Haematol. 2016 Apr; 3(4):e155-6. PMID: 27063969.
      View in: PubMed
    53. Jiang N, Wiemels RE, Soya A, Whitley R, Held M, Faik A. Composition, Assembly, and Trafficking of a Wheat Xylan Synthase Complex. Plant Physiol. 2016 04; 170(4):1999-2023. PMID: 26917684.
      View in: PubMed
    54. Carroll RK, Weiss A, Broach WH, Wiemels RE, Mogen AB, Rice KC, Shaw LN. Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus. MBio. 2016 Feb 09; 7(1):e01990-15. PMID: 26861020.
      View in: PubMed
    55. Johnson KJ, Scheurer ME, Woehrer A, Wiemels J. Evolving evidence on tumor and germline genetic classification of gliomas: implications for etiology and survival studies. Clin Neuropathol. 2016 Jan-Feb; 35(1):31-8. PMID: 26588027.
      View in: PubMed
    56. Wiemels J. New insights into childhood leukemia etiology. Eur J Epidemiol. 2015 Dec; 30(12):1225-7. PMID: 26686849.
      View in: PubMed
    57. Walsh KM, Codd V, Rice T, Nelson CP, Smirnov IV, McCoy LS, Hansen HM, Elhauge E, Ojha J, Francis SS, Madsen NR, Bracci PM, Pico AR, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD, Jenkins RB, Wiemels JL, Samani NJ, Wiencke JK, Wrensch MR. Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. Oncotarget. 2015 Dec 15; 6(40):42468-77. PMID: 26646793.
      View in: PubMed
    58. Morimoto LM, McCauley K, Ma X, Wiemels JL, Chokkalingam AP, Metayer C. Birth weight, fetal growth, and risk of pediatric rhabdomyosarcoma: an updated record linkage study in California. Ann Epidemiol. 2016 Feb; 26(2):141-145. PMID: 26795698.
      View in: PubMed
    59. de Smith AJ, Walsh KM, Hansen HM, Endicott AA, Wiencke JK, Metayer C, Wiemels JL. Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA. PLoS One. 2015; 10(11):e0143343. PMID: 26575185.
      View in: PubMed
    60. Walsh KM, de Smith AJ, Hansen HM, Smirnov IV, Gonseth S, Endicott AA, Xiao J, Rice T, Fu CH, McCoy LS, Lachance DH, Eckel-Passow JE, Wiencke JK, Jenkins RB, Wrensch MR, Ma X, Metayer C, Wiemels JL. A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution. Cancer Res. 2015 Nov 15; 75(22):4884-94. PMID: 26527286.
      View in: PubMed
    61. Lee ST, Wiemels JL. Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites. Nucleic Acids Res. 2016 Feb 18; 44(3):1105-17. PMID: 26464434.
      View in: PubMed
    62. Wiemels JL, de Smith AJ, Xiao J, Lee ST, Muench MO, Fomin ME, Zhou M, Hansen HM, Termuhlen A, Metayer C, Walsh KM. A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros. Leukemia. 2016 05; 30(5):1194-7. PMID: 26437776.
      View in: PubMed
    63. Rice T, Lachance DH, Molinaro AM, Eckel-Passow JE, Walsh KM, Barnholtz-Sloan J, Ostrom QT, Francis SS, Wiemels J, Jenkins RB, Wiencke JK, Wrensch MR. Understanding inherited genetic risk of adult glioma - a review. Neurooncol Pract. 2016 Mar; 3(1):10-16. PMID: 26941959.
      View in: PubMed
    64. Eckel-Passow JE, Lachance DH, Molinaro AM, Walsh KM, Decker PA, Sicotte H, Pekmezci M, Rice T, Kosel ML, Smirnov IV, Sarkar G, Caron AA, Kollmeyer TM, Praska CE, Chada AR, Halder C, Hansen HM, McCoy LS, Bracci PM, Marshall R, Zheng S, Reis GF, Pico AR, O'Neill BP, Buckner JC, Giannini C, Huse JT, Perry A, Tihan T, Berger MS, Chang SM, Prados MD, Wiemels J, Wiencke JK, Wrensch MR, Jenkins RB. Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med. 2015 Jun 25; 372(26):2499-508. PMID: 26061753; PMCID: PMC4489704.
      View in: PubMed, PubMed Central
    65. Kulis M, Merkel A, Heath S, Queirós AC, Schuyler RP, Castellano G, Beekman R, Raineri E, Esteve A, Clot G, Verdaguer-Dot N, Duran-Ferrer M, Russiñol N, Vilarrasa-Blasi R, Ecker S, Pancaldi V, Rico D, Agueda L, Blanc J, Richardson D, Clarke L, Datta A, Pascual M, Agirre X, Prosper F, Alignani D, Paiva B, Caron G, Fest T, Muench MO, Fomin ME, Lee ST, Wiemels JL, Valencia A, Gut M, Flicek P, Stunnenberg HG, Siebert R, Küppers R, Gut IG, Campo E, Martín-Subero JI. Whole-genome fingerprint of the DNA methylome during human B cell differentiation. Nat Genet. 2015 Jul; 47(7):746-56. PMID: 26053498.
      View in: PubMed
    66. Walsh KM, Wiencke JK, Lachance DH, Wiemels JL, Molinaro AM, Eckel-Passow JE, Jenkins RB, Wrensch MR. Telomere maintenance and the etiology of adult glioma. Neuro Oncol. 2015 Nov; 17(11):1445-52. PMID: 26014050; PMCID: PMC4648301 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    67. Barrington-Trimis JL, Cockburn M, Metayer C, Gauderman WJ, Wiemels J, McKean-Cowdin R. Rising rates of acute lymphoblastic leukemia in Hispanic children: trends in incidence from 1992 to 2011. Blood. 2015 May 07; 125(19):3033-4. PMID: 25953979.
      View in: PubMed
    68. Dahl G, Wiemels J. What causes leukemia? Pediatr Blood Cancer. 2015 Jul; 62(7):1123-4. PMID: 25894591.
      View in: PubMed
    69. Gonseth S, Nusslé S, Bovet P, Panese F, Wiemels JL. Excess winter deaths caused by cardiovascular diseases are associated with both mild winter temperature and socio-economic inequalities in the U.S. Int J Cardiol. 2015; 187:642-4. PMID: 25863741.
      View in: PubMed
    70. Hsu LI, Chokkalingam AP, Briggs FB, Walsh K, Crouse V, Fu C, Metayer C, Wiemels JL, Barcellos LF, Buffler PA. Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children. Cancer Causes Control. 2015 Apr; 26(4):609-19. PMID: 25761407.
      View in: PubMed
    71. Lee ST, Muench MO, Fomin ME, Xiao J, Zhou M, de Smith A, Martín-Subero JI, Heath S, Houseman EA, Roy R, Wrensch M, Wiencke J, Metayer C, Wiemels JL. Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures. Nucleic Acids Res. 2015 Mar 11; 43(5):2590-602. PMID: 25690899.
      View in: PubMed
    72. Zhou M, Bracci PM, McCoy LS, Hsuang G, Wiemels JL, Rice T, Zheng S, Kelsey KT, Wrensch MR, Wiencke JK. Serum macrophage-derived chemokine/CCL22 levels are associated with glioma risk, CD4 T cell lymphopenia and survival time. Int J Cancer. 2015 Aug 15; 137(4):826-36. PMID: 25604093.
      View in: PubMed
    73. Claus EB, Walsh KM, Wiencke JK, Molinaro AM, Wiemels JL, Schildkraut JM, Bondy ML, Berger M, Jenkins R, Wrensch M. Survival and low-grade glioma: the emergence of genetic information. Neurosurg Focus. 2015 Jan; 38(1):E6. PMID: 25552286; PMCID: PMC4361022.
      View in: PubMed, PubMed Central
    74. Woehrer A, Lau CC, Prayer D, Bauchet L, Rosenfeld M, Capper D, Fisher PG, Kool M, Müller M, Kros JM, Kruchko C, Wiemels J, Wrensch M, Danysh HE, Zouaoui S, Heck JE, Johnson KJ, Qi X, O'Neill BP, Afzal S, Scheurer ME, Bainbridge MN, Nousome D, Bahassi el M, Hainfellner JA, Barnholtz-Sloan JS. Brain Tumor Epidemiology - A Hub within Multidisciplinary Neuro-oncology. Report on the 15th Brain Tumor Epidemiology Consortium (BTEC) Annual Meeting, Vienna, 2014. Clin Neuropathol. 2015 Jan-Feb; 34(1):40-6. PMID: 25518914.
      View in: PubMed
    75. Gonseth S, Roy R, Houseman EA, de Smith AJ, Zhou M, Lee ST, Nusslé S, Singer AW, Wrensch MR, Metayer C, Wiemels JL. Periconceptional folate consumption is associated with neonatal DNA methylation modifications in neural crest regulatory and cancer development genes. Epigenetics. 2015; 10(12):1166-76. PMID: 26646725.
      View in: PubMed
    76. Zhang X, Xue F, Liu H, Zhu D, Peng B, Wiemels JL, Yang X. Integrative Bayesian variable selection with gene-based informative priors for genome-wide association studies. BMC Genet. 2014 Dec 10; 15:130. PMID: 25491445.
      View in: PubMed
    77. Zhang L, Samad A, Pombo-de-Oliveira MS, Scelo G, Smith MT, Feusner J, Wiemels JL, Metayer C. Global characteristics of childhood acute promyelocytic leukemia. Blood Rev. 2015 Mar; 29(2):101-25. PMID: 25445717.
      View in: PubMed
    78. Walsh KM, Codd V, Smirnov IV, Rice T, Decker PA, Hansen HM, Kollmeyer T, Kosel ML, Molinaro AM, McCoy LS, Bracci PM, Cabriga BS, Pekmezci M, Zheng S, Wiemels JL, Pico AR, Tihan T, Berger MS, Chang SM, Prados MD, Lachance DH, O'Neill BP, Sicotte H, Eckel-Passow JE, van der Harst P, Wiencke JK, Samani NJ, Jenkins RB, Wrensch MR. Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. Nat Genet. 2014 Jul; 46(7):731-5. PMID: 24908248; PMCID: PMC4074274.
      View in: PubMed, PubMed Central
    79. Walsh KM, de Smith AJ, Welch TC, Smirnov I, Cunningham MJ, Ma X, Chokkalingam AP, Dahl GV, Roberts W, Barcellos LF, Buffler PA, Metayer C, Wiemels JL. Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. Am J Hematol. 2014 Jul; 89(7):721-5. PMID: 24753091; PMCID: PMC4069235.
      View in: PubMed, PubMed Central
    80. Olson SH, Hsu M, Wiemels JL, Bracci PM, Zhou M, Patoka J, Reisacher WR, Wang J, Kurtz RC, Silverman DT, Stolzenberg-Solomon RZ. Serum immunoglobulin e and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7):1414-20. PMID: 24718282; PMCID: PMC4120187.
      View in: PubMed, PubMed Central
    81. Francis SS, Selvin S, Metayer C, Wallace AD, Crouse V, Moore TB, Wiemels JL, Buffler PA. Mode of delivery and risk of childhood leukemia. Cancer Epidemiol Biomarkers Prev. 2014 May; 23(5):876-81. PMID: 24618997.
      View in: PubMed
    82. Xiao J, Lee ST, Xiao Y, Ma X, Houseman EA, Hsu LI, Roy R, Wrensch M, de Smith AJ, Chokkalingam A, Buffler P, Wiencke JK, Wiemels JL. PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia. Int J Cancer. 2014 Sep 01; 135(5):1101-9. PMID: 24496747; PMCID: PMC4776754.
      View in: PubMed, PubMed Central
    83. de Smith AJ, Walsh KM, Ladner MB, Zhang S, Xiao C, Cohen F, Moore TB, Chokkalingam AP, Metayer C, Buffler PA, Trachtenberg EA, Wiemels JL. The role of KIR genes and their cognate HLA class I ligands in childhood acute lymphoblastic leukemia. Blood. 2014 Apr 17; 123(16):2497-503. PMID: 24518758; PMCID: PMC3990912.
      View in: PubMed, PubMed Central
    84. Diakos C, Xiao Y, Zheng S, Kager L, Dworzak M, Wiemels JL. Direct and indirect targets of the E2A-PBX1 leukemia-specific fusion protein. PLoS One. 2014; 9(2):e87602. PMID: 24503810.
      View in: PubMed
    85. Schildkraut JM, Calvocoressi L, Wang F, Wrensch M, Bondy ML, Wiemels JL, Claus EB. Endogenous and exogenous hormone exposure and the risk of meningioma in men. J Neurosurg. 2014 Apr; 120(4):820-6. PMID: 24484233.
      View in: PubMed
    86. Goodman M, LaKind JS, Fagliano JA, Lash TL, Wiemels JL, Winn DM, Patel C, Van Eenwyk J, Kohler BA, Schisterman EF, Albert P, Mattison DR. Cancer cluster investigations: review of the past and proposals for the future. Int J Environ Res Public Health. 2014 Jan 28; 11(2):1479-99. PMID: 24477211.
      View in: PubMed
    87. Walsh KM, de Smith AJ, Chokkalingam AP, Metayer C, Roberts W, Barcellos LF, Wiemels JL, Buffler PA. GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL. Blood. 2013 Nov 07; 122(19):3385-7. PMID: 24203929; PMCID: PMC3821727.
      View in: PubMed, PubMed Central
    88. Lee ST, Bracci P, Zhou M, Rice T, Wiencke J, Wrensch M, Wiemels J. Interaction of allergy history and antibodies to specific varicella-zoster virus proteins on glioma risk. Int J Cancer. 2014 May 01; 134(9):2199-210. PMID: 24127236; PMCID: PMC3951480.
      View in: PubMed, PubMed Central
    89. Urayama KY, Chokkalingam AP, Metayer C, Hansen H, May S, Ramsay P, Wiemels JL, Wiencke JK, Trachtenberg E, Thompson P, Ishida Y, Brennan P, Jolly KW, Termuhlen AM, Taylor M, Barcellos LF, Buffler PA. SNP association mapping across the extended major histocompatibility complex and risk of B-cell precursor acute lymphoblastic leukemia in children. PLoS One. 2013; 8(8):e72557. PMID: 23991122.
      View in: PubMed
    90. Metayer C, Zhang L, Wiemels JL, Bartley K, Schiffman J, Ma X, Aldrich MC, Chang JS, Selvin S, Fu CH, Ducore J, Smith MT, Buffler PA. Tobacco smoke exposure and the risk of childhood acute lymphoblastic and myeloid leukemias by cytogenetic subtype. Cancer Epidemiol Biomarkers Prev. 2013 Sep; 22(9):1600-11. PMID: 23853208; PMCID: PMC3769478.
      View in: PubMed, PubMed Central
    91. Chokkalingam AP, Hsu LI, Metayer C, Hansen HM, Month SR, Barcellos LF, Wiemels JL, Buffler PA. Genetic variants in ARID5B and CEBPE are childhood ALL susceptibility loci in Hispanics. Cancer Causes Control. 2013 Oct; 24(10):1789-95. PMID: 23836053.
      View in: PubMed
    92. Walsh KM, de Smith AJ, Chokkalingam AP, Metayer C, Dahl GV, Hsu LI, Barcellos LF, Wiemels JL, Buffler PA. Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype. Blood. 2013 Jun 06; 121(23):4808-9. PMID: 23744494.
      View in: PubMed
    93. Walsh KM, Chokkalingam AP, Hsu LI, Metayer C, de Smith AJ, Jacobs DI, Dahl GV, Loh ML, Smirnov IV, Bartley K, Ma X, Wiencke JK, Barcellos LF, Wiemels JL, Buffler PA. Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children. Leukemia. 2013 Dec; 27(12):2416-9. PMID: 23615557.
      View in: PubMed
    94. Chokkalingam AP, Chun DS, Noonan EJ, Pfeiffer CM, Zhang M, Month SR, Taggart DR, Wiemels JL, Metayer C, Buffler PA. Blood levels of folate at birth and risk of childhood leukemia. Cancer Epidemiol Biomarkers Prev. 2013 Jun; 22(6):1088-94. PMID: 23576692.
      View in: PubMed
    95. Claus EB, Wiemels J, Wrensch M. Dental x-rays and risk of meningioma: response to Drs. Calnon, Jorgensen, and White. Cancer. 2013 Jan 15; 119(2):465-6. PMID: 23254687.
      View in: PubMed
    96. Wiemels JL, Bracci PM, Wrensch M, Schildkraut J, Bondy M, Pfefferle J, Zhou M, Sison J, Calvocoressi L, Claus EB. Assessment of autoantibodies to meningioma in a population-based study. Am J Epidemiol. 2013 Jan 01; 177(1):75-83. PMID: 23221727; PMCID: PMC3590036.
      View in: PubMed, PubMed Central
    97. Chang JS, Tsai YW, Tsai CR, Wiemels JL. Allergy and risk of childhood acute lymphoblastic leukemia: a population-based and record-based study. Am J Epidemiol. 2012 Dec 01; 176(11):970-8. PMID: 23171876.
      View in: PubMed
    98. Wiencke JK, Accomando WP, Zheng S, Patoka J, Dou X, Phillips JJ, Hsuang G, Christensen BC, Houseman EA, Koestler DC, Bracci P, Wiemels JL, Wrensch M, Nelson HH, Kelsey KT. Epigenetic biomarkers of T-cells in human glioma. Epigenetics. 2012 Dec 01; 7(12):1391-402. PMID: 23108258; PMCID: PMC3528694.
      View in: PubMed, PubMed Central
    99. Claus EB, Calvocoressi L, Bondy ML, Wrensch M, Wiemels JL, Schildkraut JM. Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. J Neurosurg. 2013 Mar; 118(3):649-56. PMID: 23101448.
      View in: PubMed
    100. Lee ST, Xiao Y, Muench MO, Xiao J, Fomin ME, Wiencke JK, Zheng S, Dou X, de Smith A, Chokkalingam A, Buffler P, Ma X, Wiemels JL. A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network. Nucleic Acids Res. 2012 Dec; 40(22):11339-51. PMID: 23074194.
      View in: PubMed
    101. Paper JM, Scott-Craig JS, Cavalier D, Faik A, Wiemels RE, Borrusch MS, Bongers M, Walton JD. a-Fucosidases with different substrate specificities from two species of Fusarium. Appl Microbiol Biotechnol. 2013 Jun; 97(12):5371-80. PMID: 23011349.
      View in: PubMed
    102. Urayama KY, Chokkalingam AP, Metayer C, Ma X, Selvin S, Barcellos LF, Wiemels JL, Wiencke JK, Taylor M, Brennan P, Dahl GV, Moonsamy P, Erlich HA, Trachtenberg E, Buffler PA. HLA-DP genetic variation, proxies for early life immune modulation and childhood acute lymphoblastic leukemia risk. Blood. 2012 Oct 11; 120(15):3039-47. PMID: 22923493.
      View in: PubMed
    103. Rajaraman P, Melin BS, Wang Z, McKean-Cowdin R, Michaud DS, Wang SS, Bondy M, Houlston R, Jenkins RB, Wrensch M, Yeager M, Ahlbom A, Albanes D, Andersson U, Freeman LE, Buring JE, Butler MA, Braganza M, Carreon T, Feychting M, Fleming SJ, Gapstur SM, Gaziano JM, Giles GG, Hallmans G, Henriksson R, Hoffman-Bolton J, Inskip PD, Johansen C, Kitahara CM, Lathrop M, Liu C, Le Marchand L, Linet MS, Lonn S, Peters U, Purdue MP, Rothman N, Ruder AM, Sanson M, Sesso HD, Severi G, Shu XO, Simon M, Stampfer M, Stevens VL, Visvanathan K, White E, Wolk A, Zeleniuch-Jacquotte A, Zheng W, Decker P, Enciso-Mora V, Fridley B, Gao YT, Kosel M, Lachance DH, Lau C, Rice T, Swerdlow A, Wiemels JL, Wiencke JK, Shete S, Xiang YB, Xiao Y, Hoover RN, Fraumeni JF, Chatterjee N, Hartge P, Chanock SJ. Genome-wide association study of glioma and meta-analysis. Hum Genet. 2012 Dec; 131(12):1877-88. PMID: 22886559.
      View in: PubMed
    104. Chokkalingam AP, Metayer C, Scelo G, Chang JS, Schiffman J, Urayama KY, Ma X, Hansen HM, Feusner JH, Barcellos LF, Wiencke JK, Wiemels JL, Buffler PA. Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control. 2012 Sep; 23(9):1577-85. PMID: 22878902.
      View in: PubMed
    105. Chang JS, Tsai CR, Tsai YW, Wiemels JL. Medically diagnosed infections and risk of childhood leukaemia: a population-based case-control study. Int J Epidemiol. 2012 Aug; 41(4):1050-9. PMID: 22836110.
      View in: PubMed
    106. Chokkalingam AP, Metayer C, Scelo GA, Chang JS, Urayama KY, Aldrich MC, Guha N, Hansen HM, Dahl GV, Barcellos LF, Wiencke JK, Wiemels JL, Buffler PA. Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control. 2012 Aug; 23(8):1367-75. PMID: 22674224.
      View in: PubMed
    107. Nelson HH, Marsit CJ, Christensen BC, Houseman EA, Kontic M, Wiemels JL, Karagas MR, Wrensch MR, Zheng S, Wiencke JK, Kelsey KT. Key epigenetic changes associated with lung cancer development: results from dense methylation array profiling. Epigenetics. 2012 Jun 01; 7(6):559-66. PMID: 22522909.
      View in: PubMed
    108. Seiler RL, Wiemels JL. Occurrence of ²¹°Po and biological effects of low-level exposure: the need for research. Environ Health Perspect. 2012 Sep; 120(9):1230-7. PMID: 22538346.
      View in: PubMed
    109. Bracci PM, Zhou M, Young S, Wiemels J. Serum autoantibodies to pancreatic cancer antigens as biomarkers of pancreatic cancer in a San Francisco Bay Area case-control study. Cancer. 2012 Nov 01; 118(21):5384-94. PMID: 22517435; PMCID: PMC3414682.
      View in: PubMed, PubMed Central
    110. Claus EB, Calvocoressi L, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M. Dental x-rays and risk of meningioma. Cancer. 2012 Sep 15; 118(18):4530-7. PMID: 22492363.
      View in: PubMed
    111. Claus EB, Walsh KM, Calvocoressi L, Bondy ML, Schildkraut JM, Wrensch M, Wiemels JL. Cigarette smoking and risk of meningioma: the effect of gender. Cancer Epidemiol Biomarkers Prev. 2012 Jun; 21(6):943-50. PMID: 22473761.
      View in: PubMed
    112. Wiemels J. Perspectives on the causes of childhood leukemia. Chem Biol Interact. 2012 Apr 05; 196(3):59-67. PMID: 22326931.
      View in: PubMed
    113. Mansur MB, Hassan R, Barbosa TC, Splendore A, Jotta PY, Yunes JA, Wiemels JL, Pombo-de-Oliveira MS. Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia. BMC Cancer. 2012 Jan 06; 12:9. PMID: 22225590.
      View in: PubMed
    114. Vasconcelos GM, Christensen BC, Houseman EA, Xiao J, Marsit CJ, Wiencke JK, Zheng S, Karagas MR, Nelson HH, Wrensch MR, Kelsey KT, Pombo-de-Oliveira MS, Wiemels JL. History of Parvovirus B19 infection is associated with a DNA methylation signature in childhood acute lymphoblastic leukemia. Epigenetics. 2011 Dec; 6(12):1436-43. PMID: 22139573.
      View in: PubMed
    115. Joannides M, Mays AN, Mistry AR, Hasan SK, Reiter A, Wiemels JL, Felix CA, Coco FL, Osheroff N, Solomon E, Grimwade D. Molecular pathogenesis of secondary acute promyelocytic leukemia. Mediterr J Hematol Infect Dis. 2011; 3(1):e2011045. PMID: 22110895.
      View in: PubMed
    116. Chokkalingam AP, Bartley K, Wiemels JL, Metayer C, Barcellos LF, Hansen HM, Aldrich MC, Guha N, Urayama KY, Scélo G, Chang JS, Month SR, Wiencke JK, Buffler PA. Haplotypes of DNA repair and cell cycle control genes, X-ray exposure, and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control. 2011 Dec; 22(12):1721-30. PMID: 21987080.
      View in: PubMed
    117. Chokkalingam AP, Aldrich MC, Bartley K, Hsu LI, Metayer C, Barcellos LF, Wiemels JL, Wiencke JK, Buffler PA, Selvin S. Matching on Race and Ethnicity in Case-Control Studies as a Means of Control for Population Stratification. Epidemiology (Sunnyvale). 2011 Sep 29; 1:101. PMID: 24683503.
      View in: PubMed
    118. Wiemels JL, Wiencke JK, Li Z, Ramos C, Nelson HH, Karagas MR. Risk of squamous cell carcinoma of the skin in relation to IgE: a nested case-control study. Cancer Epidemiol Biomarkers Prev. 2011 Nov; 20(11):2377-83. PMID: 21949109.
      View in: PubMed
    119. Claus EB, Calvocoressi L, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M. Family and personal medical history and risk of meningioma. J Neurosurg. 2011 Dec; 115(6):1072-7. PMID: 21780859.
      View in: PubMed
    120. Metayer C, Scélo G, Chokkalingam AP, Barcellos LF, Aldrich MC, Chang JS, Guha N, Urayama KY, Hansen HM, Block G, Kiley V, Wiencke JK, Wiemels JL, Buffler PA. Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control. 2011 Sep; 22(9):1243-58. PMID: 21748308.
      View in: PubMed
    121. Lachance DH, Yang P, Johnson DR, Decker PA, Kollmeyer TM, McCoy LS, Rice T, Xiao Y, Ali-Osman F, Wang F, Stoddard SM, Sprau DJ, Kosel ML, Wiencke JK, Wiemels JL, Patoka JS, Davis F, McCarthy B, Rynearson AL, Worra JB, Fridley BL, O'Neill BP, Buckner JC, Il'yasova D, Jenkins RB, Wrensch MR. Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking. Am J Epidemiol. 2011 Sep 01; 174(5):574-81. PMID: 21742680; PMCID: PMC3202152.
      View in: PubMed, PubMed Central
    122. Chang JS, Zhou M, Buffler PA, Chokkalingam AP, Metayer C, Wiemels JL. Profound deficit of IL10 at birth in children who develop childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2011 Aug; 20(8):1736-40. PMID: 21653647.
      View in: PubMed
    123. Wiemels JL, Wrensch M, Sison JD, Zhou M, Bondy M, Calvocoressi L, Black PM, Yu H, Schildkraut JM, Claus EB. Reduced allergy and immunoglobulin E among adults with intracranial meningioma compared to controls. Int J Cancer. 2011 Oct 15; 129(8):1932-9. PMID: 21520030; PMCID: PMC3337969.
      View in: PubMed, PubMed Central
    124. Zheng S, Houseman EA, Morrison Z, Wrensch MR, Patoka JS, Ramos C, Haas-Kogan DA, McBride S, Marsit CJ, Christensen BC, Nelson HH, Stokoe D, Wiemels JL, Chang SM, Prados MD, Tihan T, Vandenberg SR, Kelsey KT, Berger MS, Wiencke JK. DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro Oncol. 2011 Mar; 13(3):280-9. PMID: 21339190; PMCID: PMC3064601.
      View in: PubMed, PubMed Central
    125. Francis SS, Selvin S, Yang W, Buffler PA, Wiemels JL. Unusual space-time patterning of the Fallon, Nevada leukemia cluster: Evidence of an infectious etiology. Chem Biol Interact. 2012 Apr 05; 196(3):102-9. PMID: 21352818; PMCID: PMC3839794.
      View in: PubMed, PubMed Central
    126. Jenkins RB, Wrensch MR, Johnson D, Fridley BL, Decker PA, Xiao Y, Kollmeyer TM, Rynearson AL, Fink S, Rice T, McCoy LS, Halder C, Kosel ML, Giannini C, Tihan T, O'Neill BP, Lachance DH, Yang P, Wiemels J, Wiencke JK. Distinct germ line polymorphisms underlie glioma morphologic heterogeneity. Cancer Genet. 2011 Jan; 204(1):13-8. PMID: 21356187.
      View in: PubMed
    127. Urayama KY, Ma X, Selvin S, Metayer C, Chokkalingam AP, Wiemels JL, Does M, Chang J, Wong A, Trachtenberg E, Buffler PA. Early life exposure to infections and risk of childhood acute lymphoblastic leukemia. Int J Cancer. 2011 Apr 01; 128(7):1632-43. PMID: 21280034.
      View in: PubMed
    128. Christensen BC, Smith AA, Zheng S, Koestler DC, Houseman EA, Marsit CJ, Wiemels JL, Nelson HH, Karagas MR, Wrensch MR, Kelsey KT, Wiencke JK. DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst. 2011 Jan 19; 103(2):143-53. PMID: 21163902.
      View in: PubMed
    129. Chang P, Kang M, Xiao A, Chang J, Feusner J, Buffler P, Wiemels J. FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemia. BMC Cancer. 2010 Sep 27; 10:513. PMID: 20875128.
      View in: PubMed
    130. Wiemels J, Wrensch M, Claus EB. Epidemiology and etiology of meningioma. J Neurooncol. 2010 Sep; 99(3):307-14. PMID: 20821343; PMCID: PMC2945461.
      View in: PubMed, PubMed Central
    131. Diakos C, Zhong S, Xiao Y, Zhou M, Vasconcelos GM, Krapf G, Yeh RF, Zheng S, Kang M, Wiencke JK, Pombo-de-Oliveira MS, Panzer-Grümayer R, Wiemels JL. TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a. Blood. 2010 Dec 02; 116(23):4885-93. PMID: 20807887.
      View in: PubMed
    132. Marsit CJ, Houseman EA, Christensen BC, Gagne L, Wrensch MR, Nelson HH, Wiemels J, Zheng S, Wiencke JK, Andrew AS, Schned AR, Karagas MR, Kelsey KT. Identification of methylated genes associated with aggressive bladder cancer. PLoS One. 2010 Aug 23; 5(8):e12334. PMID: 20808801.
      View in: PubMed
    133. Zhou M, Wiemels JL, Bracci PM, Wrensch MR, McCoy LS, Rice T, Sison JD, Patoka JS, Wiencke JK. Circulating levels of the innate and humoral immune regulators CD14 and CD23 are associated with adult glioma. Cancer Res. 2010 Oct 01; 70(19):7534-42. PMID: 20719886; PMCID: PMC3339633.
      View in: PubMed, PubMed Central
    134. Chang JS, Wiemels JL, Chokkalingam AP, Metayer C, Barcellos LF, Hansen HM, Aldrich MC, Guha N, Urayama KY, Scélo G, Green J, May SL, Kiley VA, Wiencke JK, Buffler PA. Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2010 Sep; 19(9):2152-63. PMID: 20716621; PMCID: PMC3257312.
      View in: PubMed, PubMed Central
    135. Score J, Calasanz MJ, Ottman O, Pane F, Yeh RF, Sobrinho-Simões MA, Kreil S, Ward D, Hidalgo-Curtis C, Melo JV, Wiemels J, Nadel B, Cross NC, Grand FH. Analysis of genomic breakpoints in p190 and p210 BCR-ABL indicate distinct mechanisms of formation. Leukemia. 2010 Oct; 24(10):1742-50. PMID: 20703256.
      View in: PubMed
    136. Wiemels JL, Kang M, Chang JS, Zheng L, Kouyoumji C, Zhang L, Smith MT, Scelo G, Metayer C, Buffler P, Wiencke JK. Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia. Blood Cells Mol Dis. 2010 Oct 15; 45(3):186-91. PMID: 20688547.
      View in: PubMed
    137. Hasan SK, Ottone T, Schlenk RF, Xiao Y, Wiemels JL, Mitra ME, Bernasconi P, Di Raimondo F, Stanghellini MT, Marco P, Mays AN, Döhner H, Sanz MA, Amadori S, Grimwade D, Lo-Coco F. Analysis of t(15;17) chromosomal breakpoint sequences in therapy-related versus de novo acute promyelocytic leukemia: association of DNA breaks with specific DNA motifs at PML and RARA loci. Genes Chromosomes Cancer. 2010 Aug; 49(8):726-32. PMID: 20544846.
      View in: PubMed
    138. Christensen BC, Kelsey KT, Zheng S, Houseman EA, Marsit CJ, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Kushi LH, Kwan ML, Wiencke JK. Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet. 2010 Jul 29; 6(7):e1001043. PMID: 20686660; PMCID: PMC2912395.
      View in: PubMed, PubMed Central
    139. Mays AN, Osheroff N, Xiao Y, Wiemels JL, Felix CA, Byl JA, Saravanamuttu K, Peniket A, Corser R, Chang C, Hoyle C, Parker AN, Hasan SK, Lo-Coco F, Solomon E, Grimwade D. Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia. Blood. 2010 Jan 14; 115(2):326-30. PMID: 19884644.
      View in: PubMed
    140. Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet. 2009 Aug; 5(8):e1000602. PMID: 19680444; PMCID: PMC2718614.
      View in: PubMed, PubMed Central
    141. Wiemels JL, Wilson D, Patil C, Patoka J, McCoy L, Rice T, Schwartzbaum J, Heimberger A, Sampson JH, Chang S, Prados M, Wiencke JK, Wrensch M. IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era. Int J Cancer. 2009 Aug 01; 125(3):680-7. PMID: 19408307; PMCID: PMC2861569.
      View in: PubMed, PubMed Central
    142. Christensen BC, Marsit CJ, Houseman EA, Godleski JJ, Longacker JL, Zheng S, Yeh RF, Wrensch MR, Wiemels JL, Karagas MR, Bueno R, Sugarbaker DJ, Nelson HH, Wiencke JK, Kelsey KT. Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles. Cancer Res. 2009 Aug 01; 69(15):6315-21. PMID: 19638575.
      View in: PubMed
    143. Chang JS, Buffler PA, Metayer C, Chokkalingam AP, Patoka J, Kronish D, Wiemels JL. Maternal immunoglobulin E and childhood leukemia. Cancer Epidemiol Biomarkers Prev. 2009 Aug; 18(8):2221-7. PMID: 19622720.
      View in: PubMed
    144. Houseman EA, Christensen BC, Karagas MR, Wrensch MR, Nelson HH, Wiemels JL, Zheng S, Wiencke JK, Kelsey KT, Marsit CJ. Copy number variation has little impact on bead-array-based measures of DNA methylation. Bioinformatics. 2009 Aug 15; 25(16):1999-2005. PMID: 19542153.
      View in: PubMed
    145. Sapru A, Hansen H, Ajayi T, Brown R, Garcia O, Zhuo H, Wiemels J, Matthay MA, Wiener-Kronish J. 4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia. Anesthesiology. 2009 May; 110(5):1086-91. PMID: 19387177; PMCID: PMC4127307.
      View in: PubMed, PubMed Central
    146. Marsit CJ, Christensen BC, Houseman EA, Karagas MR, Wrensch MR, Yeh RF, Nelson HH, Wiemels JL, Zheng S, Posner MR, McClean MD, Wiencke JK, Kelsey KT. Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis. 2009 Mar; 30(3):416-22. PMID: 19126652.
      View in: PubMed
    147. Wiemels J, Kang M, Greaves M. Backtracking of leukemic clones to birth. Methods Mol Biol. 2009; 538:7-27. PMID: 19277581.
      View in: PubMed
    148. Ma X, Urayama K, Chang J, Wiemels JL, Buffler PA. Infection and pediatric acute lymphoblastic leukemia. Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):117-20. PMID: 19064328.
      View in: PubMed
    149. Chang JS, Wiemels JL, Buffler PA. Allergies and childhood leukemia. Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):99-104. PMID: 19049852.
      View in: PubMed
    150. Wiemels JL, Hofmann J, Kang M, Selzer R, Green R, Zhou M, Zhong S, Zhang L, Smith MT, Marsit C, Loh M, Buffler P, Yeh RF. Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally. Cancer Res. 2008 Dec 01; 68(23):9935-44. PMID: 19047175.
      View in: PubMed
    151. Walz C, Score J, Mix J, Cilloni D, Roche-Lestienne C, Yeh RF, Wiemels JL, Ottaviani E, Erben P, Hochhaus A, Baccarani M, Grimwade D, Preudhomme C, Apperley J, Martinelli G, Saglio G, Cross NC, Reiter A. The molecular anatomy of the FIP1L1-PDGFRA fusion gene. Leukemia. 2009 Feb; 23(2):271-8. PMID: 18987651.
      View in: PubMed
    152. Pico AR, Smirnov IV, Chang JS, Yeh RF, Wiemels JL, Wiencke JK, Tihan T, Conklin BR, Wrensch M. SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system. Nucleic Acids Res. 2009 Jan; 37(Database issue):D803-9. PMID: 18984625; PMCID: PMC2686434.
      View in: PubMed, PubMed Central
    153. Vasconcelos GM, Kang M, Pombo-de-Oliveira MS, Schiffman JD, Lorey F, Buffler P, Wiemels JL. Adenovirus detection in Guthrie cards from paediatric leukaemia cases and controls. Br J Cancer. 2008 Nov 18; 99(10):1668-72. PMID: 19002185.
      View in: PubMed
    154. Guha N, Chang JS, Chokkalingam AP, Wiemels JL, Smith MT, Buffler PA. NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysis. Am J Epidemiol. 2008 Dec 01; 168(11):1221-32. PMID: 18945694.
      View in: PubMed
    155. Scélo G, Metayer C, Zhang L, Wiemels JL, Aldrich MC, Selvin S, Month S, Smith MT, Buffler PA. Household exposure to paint and petroleum solvents, chromosomal translocations, and the risk of childhood leukemia. Environ Health Perspect. 2009 Jan; 117(1):133-9. PMID: 19165400.
      View in: PubMed
    156. Bondy ML, Scheurer ME, Malmer B, Barnholtz-Sloan JS, Davis FG, Il'yasova D, Kruchko C, McCarthy BJ, Rajaraman P, Schwartzbaum JA, Sadetzki S, Schlehofer B, Tihan T, Wiemels JL, Wrensch M, Buffler PA. Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer. 2008 Oct 01; 113(7 Suppl):1953-68. PMID: 18798534.
      View in: PubMed
    157. Houseman EA, Christensen BC, Yeh RF, Marsit CJ, Karagas MR, Wrensch M, Nelson HH, Wiemels J, Zheng S, Wiencke JK, Kelsey KT. Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics. 2008 Sep 09; 9:365. PMID: 18782434.
      View in: PubMed
    158. Chang JS, Yeh RF, Wiencke JK, Wiemels JL, Smirnov I, Pico AR, Tihan T, Patoka J, Miike R, Sison JD, Rice T, Wrensch MR. Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests. Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6):1368-73. PMID: 18559551.
      View in: PubMed
    159. Wiemels J. Chromosomal translocations in childhood leukemia: natural history, mechanisms, and epidemiology. J Natl Cancer Inst Monogr. 2008; (39):87-90. PMID: 18648011.
      View in: PubMed
    160. Fisher JL, Schwartzbaum JA, Wrensch M, Wiemels JL. Epidemiology of brain tumors. Neurol Clin. 2007 Nov; 25(4):867-90, vii. PMID: 17964019.
      View in: PubMed
    161. Claus EB, Black PM, Bondy ML, Calvocoressi L, Schildkraut JM, Wiemels JL, Wrensch M. Exogenous hormone use and meningioma risk: what do we tell our patients? Cancer. 2007 Aug 01; 110(3):471-6. PMID: 17580362.
      View in: PubMed
    162. Hansen HM, Wiemels JL, Wrensch M, Wiencke JK. DNA quantification of whole genome amplified samples for genotyping on a multiplexed bead array platform. Cancer Epidemiol Biomarkers Prev. 2007 Aug; 16(8):1686-90. PMID: 17684147.
      View in: PubMed
    163. Urayama KY, Wiencke JK, Buffler PA, Chokkalingam AP, Metayer C, Wiemels JL. MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1172-7. PMID: 17548681.
      View in: PubMed
    164. Wiemels JL, Wiencke JK, Kelsey KT, Moghadassi M, Rice T, Urayama KY, Miike R, Wrensch M. Allergy-related polymorphisms influence glioma status and serum IgE levels. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1229-35. PMID: 17548690.
      View in: PubMed
    165. Busch K, Keller T, Fuchs U, Yeh RF, Harbott J, Klose I, Wiemels J, Novosel A, Reiter A, Borkhardt A. Identification of two distinct MYC breakpoint clusters and their association with various IGH breakpoint regions in the t(8;14) translocations in sporadic Burkitt-lymphoma. Leukemia. 2007 Aug; 21(8):1739-51. PMID: 17541401.
      View in: PubMed
    166. Paynter RA, Skibola DR, Skibola CF, Buffler PA, Wiemels JL, Smith MT. Accuracy of multiplexed Illumina platform-based single-nucleotide polymorphism genotyping compared between genomic and whole genome amplified DNA collected from multiple sources. Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2533-6. PMID: 17164381.
      View in: PubMed
    167. Sapru A, Wiemels JL, Witte JS, Ware LB, Matthay MA. Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Med. 2006 Sep; 32(9):1293-303. PMID: 16770611.
      View in: PubMed
    168. Aldrich MC, Zhang L, Wiemels JL, Ma X, Loh ML, Metayer C, Selvin S, Feusner J, Smith MT, Buffler PA. Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in California. Cancer Epidemiol Biomarkers Prev. 2006 Mar; 15(3):578-81. PMID: 16537719.
      View in: PubMed
    169. Claus EB, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M, Black PM. Epidemiology of intracranial meningioma. Neurosurgery. 2005 Dec; 57(6):1088-95; discussion 1088-95. PMID: 16331155.
      View in: PubMed
    170. Wrensch M, Kelsey KT, Liu M, Miike R, Moghadassi M, Sison JD, Aldape K, McMillan A, Wiemels J, Wiencke JK. ERCC1 and ERCC2 polymorphisms and adult glioma. Neuro Oncol. 2005 Oct; 7(4):495-507. PMID: 16212814; PMCID: PMC1871723.
      View in: PubMed, PubMed Central
    171. Kwan ML, Buffler PA, Wiemels JL, Metayer C, Selvin S, Ducore JM, Block G. Breastfeeding patterns and risk of childhood acute lymphoblastic leukaemia. Br J Cancer. 2005 Aug 08; 93(3):379-84. PMID: 16052219; PMCID: PMC2361562.
      View in: PubMed, PubMed Central
    172. Smith MT, McHale CM, Wiemels JL, Zhang L, Wiencke JK, Zheng S, Gunn L, Skibola CF, Ma X, Buffler PA. Molecular biomarkers for the study of childhood leukemia. Toxicol Appl Pharmacol. 2005 Aug 07; 206(2):237-45. PMID: 15967214.
      View in: PubMed
    173. Ma X, Buffler PA, Wiemels JL, Selvin S, Metayer C, Loh M, Does MB, Wiencke JK. Ethnic difference in daycare attendance, early infections, and risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2005 Aug; 14(8):1928-34. PMID: 16103439.
      View in: PubMed
    174. Wrensch M, Weinberg A, Wiencke J, Miike R, Sison J, Wiemels J, Barger G, DeLorenze G, Aldape K, Kelsey K. History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpesviruses among adults with glioma and controls. Am J Epidemiol. 2005 May 15; 161(10):929-38. PMID: 15870157.
      View in: PubMed
    175. Mistry AR, Felix CA, Whitmarsh RJ, Mason A, Reiter A, Cassinat B, Parry A, Walz C, Wiemels JL, Segal MR, Adès L, Blair IA, Osheroff N, Peniket AJ, Lafage-Pochitaloff M, Cross NC, Chomienne C, Solomon E, Fenaux P, Grimwade D. DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med. 2005 Apr 14; 352(15):1529-38. PMID: 15829534.
      View in: PubMed
    176. Wiemels JL, Zhang Y, Chang J, Zheng S, Metayer C, Zhang L, Smith MT, Ma X, Selvin S, Buffler PA, Wiencke JK. RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia. Leukemia. 2005 Mar; 19(3):415-9. PMID: 15674422.
      View in: PubMed
    177. Wiemels JL, Wiencke JK, Patoka J, Moghadassi M, Chew T, McMillan A, Miike R, Barger G, Wrensch M. Reduced immunoglobulin E and allergy among adults with glioma compared with controls. Cancer Res. 2004 Nov 15; 64(22):8468-73. PMID: 15548720.
      View in: PubMed
    178. Maia AT, Koechling J, Corbett R, Metzler M, Wiemels JL, Greaves M. Protracted postnatal natural histories in childhood leukemia. Genes Chromosomes Cancer. 2004 Apr; 39(4):335-40. PMID: 14978794.
      View in: PubMed
    179. Zheng S, Ma X, Zhang L, Gunn L, Smith MT, Wiemels JL, Leung K, Buffler PA, Wiencke JK. Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia. Cancer Res. 2004 Mar 15; 64(6):2000-6. PMID: 15026336.
      View in: PubMed
    180. Greaves MF, Maia AT, Wiemels JL, Ford AM. Leukemia in twins: lessons in natural history. Blood. 2003 Oct 01; 102(7):2321-33. PMID: 12791663.
      View in: PubMed
    181. McHale CM, Wiemels JL, Zhang L, Ma X, Buffler PA, Feusner J, Matthay K, Dahl G, Smith MT. Prenatal origin of childhood acute myeloid leukemias harboring chromosomal rearrangements t(15;17) and inv(16). Blood. 2003 Jun 01; 101(11):4640-1. PMID: 12756163.
      View in: PubMed
    182. McHale CM, Wiemels JL, Zhang L, Ma X, Buffler PA, Guo W, Loh ML, Smith MT. Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in California. Genes Chromosomes Cancer. 2003 May; 37(1):36-43. PMID: 12661004.
      View in: PubMed
    183. Pine SR, Wiemels JL, Jayabose S, Sandoval C. TEL-AML1 fusion precedes differentiation to pre-B cells in childhood acute lymphoblastic leukemia. Leuk Res. 2003 Feb; 27(2):155-64. PMID: 12526921.
      View in: PubMed
    184. Pine SR, Moy FH, Wiemels JL, Gill RK, Levendoglu-Tugal O, Ozkaynak MF, Sandoval C, Jayabose S. Real-time quantitative PCR: standardized detection of minimal residual disease in pediatric acute lymphoblastic leukemia. Polymerase chain reaction. J Pediatr Hematol Oncol. 2003 Feb; 25(2):103-8. PMID: 12571459.
      View in: PubMed
    185. Reiter A, Saussele S, Grimwade D, Wiemels JL, Segal MR, Lafage-Pochitaloff M, Walz C, Weisser A, Hochhaus A, Willer A, Reichert A, Büchner T, Lengfelder E, Hehlmann R, Cross NC. Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia. Genes Chromosomes Cancer. 2003 Feb; 36(2):175-88. PMID: 12508246.
      View in: PubMed
    186. Wiemels JL, Leonard BC, Wang Y, Segal MR, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, Pine SR. Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):15101-6. PMID: 12415113; PMCID: PMC137550.
      View in: PubMed, PubMed Central
    187. Wiemels JL, Xiao Z, Buffler PA, Maia AT, Ma X, Dicks BM, Smith MT, Zhang L, Feusner J, Wiencke J, Pritchard-Jones K, Kempski H, Greaves M. In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia. Blood. 2002 May 15; 99(10):3801-5. PMID: 11986239.
      View in: PubMed
    188. Ma X, Buffler PA, Selvin S, Matthay KK, Wiencke JK, Wiemels JL, Reynolds P. Daycare attendance and risk of childhood acute lymphoblastic leukaemia. Br J Cancer. 2002 May 06; 86(9):1419-24. PMID: 11986774; PMCID: PMC2375371.
      View in: PubMed, PubMed Central
    189. Wiemels JL, Wiencke JK, Sison JD, Miike R, McMillan A, Wrensch M. History of allergies among adults with glioma and controls. Int J Cancer. 2002 Apr 01; 98(4):609-15. PMID: 11920623.
      View in: PubMed
    190. Xiao Z, Greaves MF, Buffler P, Smith MT, Segal MR, Dicks BM, Wiencke JK, Wiemels JL. Molecular characterization of genomic AML1-ETO fusions in childhood leukemia. Leukemia. 2001 Dec; 15(12):1906-13. PMID: 11753612.
      View in: PubMed
    191. Hayes RB, Zhang L, Swenberg JA, Yin SN, Xi L, Wiencke J, Bechtold WE, Yao M, Rothman N, Haas R, O'Neill JP, Wiemels J, Dosemeci M, Li G, Smith MT. Markers for carcinogenicity among butadiene-polymer workers in China. Chem Biol Interact. 2001 Jun 01; 135-136:455-64. PMID: 11397406.
      View in: PubMed
    192. Alexander FE, Patheal SL, Biondi A, Brandalise S, Cabrera ME, Chan LC, Chen Z, Cimino G, Cordoba JC, Gu LJ, Hussein H, Ishii E, Kamel AM, Labra S, Magalhães IQ, Mizutani S, Petridou E, de Oliveira MP, Yuen P, Wiemels JL, Greaves MF. Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. Cancer Res. 2001 Mar 15; 61(6):2542-6. PMID: 11289128.
      View in: PubMed
    193. Wiemels JL, Smith RN, Taylor GM, Eden OB, Alexander FE, Greaves MF. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Proc Natl Acad Sci U S A. 2001 Mar 27; 98(7):4004-9. PMID: 11274424; PMCID: PMC31169.
      View in: PubMed, PubMed Central
    194. Smith MT, Wang Y, Kane E, Rollinson S, Wiemels JL, Roman E, Roddam P, Cartwright R, Morgan G. Low NAD(P)H:quinone oxidoreductase 1 activity is associated with increased risk of acute leukemia in adults. Blood. 2001 Mar 01; 97(5):1422-6. PMID: 11222389.
      View in: PubMed
    195. Wiemels JL, Alexander FE, Cazzaniga G, Biondi A, Mayer SP, Greaves M. Microclustering of TEL-AML1 translocation breakpoints in childhood acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2000 Nov; 29(3):219-28. PMID: 10992297.
      View in: PubMed
    196. Naoe T, Takeyama K, Yokozawa T, Kiyoi H, Seto M, Uike N, Ino T, Utsunomiya A, Maruta A, Jin-nai I, Kamada N, Kubota Y, Nakamura H, Shimazaki C, Horiike S, Kodera Y, Saito H, Ueda R, Wiemels J, Ohno R. Analysis of genetic polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese patients with therapy-related leukemia/ myelodysplastic syndrome and de novo acute myeloid leukemia. Clin Cancer Res. 2000 Oct; 6(10):4091-5. PMID: 11051261.
      View in: PubMed
    197. Hayes RB, Zhang L, Yin S, Swenberg JA, Xi L, Wiencke J, Bechtold WE, Yao M, Rothman N, Haas R, O'Neill JP, Zhang D, Wiemels J, Dosemeci M, Li G, Smith MT. Genotoxic markers among butadiene polymer workers in China. Carcinogenesis. 2000 Jan; 21(1):55-62. PMID: 10607734.
      View in: PubMed
    198. Wiemels JL, Cazzaniga G, Daniotti M, Eden OB, Addison GM, Masera G, Saha V, Biondi A, Greaves MF. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet. 1999 Oct 30; 354(9189):1499-503. PMID: 10551495.
      View in: PubMed
    199. Wiemels JL, Pagnamenta A, Taylor GM, Eden OB, Alexander FE, Greaves MF. A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. United Kingdom Childhood Cancer Study Investigators. Cancer Res. 1999 Aug 15; 59(16):4095-9. PMID: 10463613.
      View in: PubMed
    200. Wiemels JL, Greaves M. Structure and possible mechanisms of TEL-AML1 gene fusions in childhood acute lymphoblastic leukemia. Cancer Res. 1999 Aug 15; 59(16):4075-82. PMID: 10463610.
      View in: PubMed
    201. Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood. 1999 Aug 01; 94(3):1057-62. PMID: 10419898.
      View in: PubMed
    202. Larson RA, Wang Y, Banerjee M, Wiemels J, Hartford C, Le Beau MM, Smith MT. Prevalence of the inactivating 609C-->T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia. Blood. 1999 Jul 15; 94(2):803-7. PMID: 10397748.
      View in: PubMed
    203. Wiemels J, Wiencke JK, Varykoni A, Smith MT. Modulation of the toxicity and macromolecular binding of benzene metabolites by NAD(P)H:Quinone oxidoreductase in transfected HL-60 cells. Chem Res Toxicol. 1999 Jun; 12(6):467-75. PMID: 10368308.
      View in: PubMed
    204. Wiemels J, Smith MT. Enhancement of myeloid cell growth by benzene metabolites via the production of active oxygen species. Free Radic Res. 1999 Feb; 30(2):93-103. PMID: 10193577.
      View in: PubMed
    205. Smith MT, Zhang L, Wang Y, Hayes RB, Li G, Wiemels J, Dosemeci M, Titenko-Holland N, Xi L, Kolachana P, Yin S, Rothman N. Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene. Cancer Res. 1998 May 15; 58(10):2176-81. PMID: 9605763.
      View in: PubMed
    206. Rothman N, Smith MT, Hayes RB, Li GL, Irons RD, Dosemeci M, Haas R, Stillman WS, Linet M, Xi LQ, Bechtold WE, Wiemels J, Campleman S, Zhang L, Quintana PJ, Titenko-Holland N, Wang YZ, Lu W, Kolachana P, Meyer KB, Yin S. An epidemiologic study of early biologic effects of benzene in Chinese workers. Environ Health Perspect. 1996 Dec; 104 Suppl 6:1365-70. PMID: 9118921.
      View in: PubMed
    207. Hayes RB, Xi L, Bechtold WE, Rothman N, Yao M, Henderson R, Zhang L, Smith MT, Zhang D, Wiemels J, Dosemeci M, Yin S, O'Neill JP. hprt mutation frequency among workers exposed to 1,3-butadiene in China. Toxicology. 1996 Oct 28; 113(1-3):100-5. PMID: 8901888.
      View in: PubMed
    208. Wiencke JK, Wiemels J. Genotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Mutat Res. 1995 Jun; 339(2):91-119. PMID: 7791804.
      View in: PubMed
    209. Rothman N, Haas R, Hayes RB, Li GL, Wiemels J, Campleman S, Quintana PJ, Xi LJ, Dosemeci M, Titenko-Holland N. Benzene induces gene-duplicating but not gene-inactivating mutations at the glycophorin A locus in exposed humans. Proc Natl Acad Sci U S A. 1995 Apr 25; 92(9):4069-73. PMID: 7732033; PMCID: PMC42104.
      View in: PubMed, PubMed Central
    210. Smith MT, Wiemels J, Rothman N, Linet MS. Chemical exposure, ras oncogene activation, and acute myeloid leukemia. J Natl Cancer Inst. 1992 Nov 04; 84(21):1614-5. PMID: 1433339.
      View in: PubMed
    211. Levison BS, Wiemels J, Szasz J, Sternlicht H. Ethoxyformylation of tubulin with [3H]diethyl pyrocarbonate: a reexamination of the mechanism of assembly inhibition. Biochemistry. 1989 Oct 31; 28(22):8877-84. PMID: 2605229.
      View in: PubMed
    Joe's Networks
    Concepts
    Derived automatically from this person's publications.
    See all (702) concept(s)
    _
    Co-Authors
    People in Profiles who have published with this person.
    See all (67) people
    _
    Similar People
    People who share similar concepts with this person.
    See all (60) people
    _
    Same Department
    Search Department
    ↑