Nick Paras, PhD

Title(s)Professor, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
ORCID ORCID Icon0000-0001-5742-4056 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent. Org Lett. 2021 05 21; 23(10):3823-3827. Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. PMID: 33929208.
      View in: PubMed   Mentions:    Fields:    
    2. Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles. ACS Omega. 2021 Apr 13; 6(14):9804-9812. Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J. PMID: 33869960.
      View in: PubMed   Mentions:
    3. Selectivity in the Addition of Electron‐Deficient Radicals to the C2 Position of Indoles. European Journal of Organic Chemistry. 2020; 2020(36):5828-5832. Yi Li, Roy J Vaz, Steven H Olson, Mark Munson, Nick A Paras, Jay Conrad. View Publication.
    4. Expanding spectrum of prion diseases. Emerg Top Life Sci. 2020 09 08; 4(2):155-167. Ayers JI, Paras NA, Prusiner SB. PMID: 32803268.
      View in: PubMed   Mentions:
    5. Selectivity in the Addition of Electron Deficient Radicals to the C2 Position of Indoles. European J Org Chem. 2020 Sep 30; 2020(36):5828-5832. Li Y, Vaz RJ, Olson SH, Munson M, Paras NA, Conrad J. PMID: 33692651.
      View in: PubMed   Mentions:
    6. Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. ACS Med Chem Lett. 2020 Feb 13; 11(2):127-132. Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. PMID: 32071678.
      View in: PubMed   Mentions:
    7. AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies. Cancer Discov. 2018 12; 8(12):1582-1597. Caenepeel S, Brown SP, Belmontes B, Moody G, Keegan KS, Chui D, Whittington DA, Huang X, Poppe L, Cheng AC, Cardozo M, Houze J, Li Y, Lucas B, Paras NA, Wang X, Taygerly JP, Vimolratana M, Zancanella M, Zhu L, Cajulis E, Osgood T, Sun J, Damon L, Egan RK, Greninger P, McClanaghan JD, Gong J, Moujalled D, Pomilio G, Beltran P, Benes CH, Roberts AW, Huang DC, Wei A, Canon J, Coxon A, Hughes PE. PMID: 30254093.
      View in: PubMed   Mentions: 82     Fields:    
    8. Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism. J Org Chem. 2018 08 17; 83(16):8926-8935. O'Brien CJ, Droege DG, Jiu AY, Gandhi SS, Paras NA, Olson SH, Conrad J. PMID: 29940725.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    9. Deutetrabenazine for Treatment of Chorea in Huntington Disease. JAMA. 2016 Jul 05; 316(1):33-5. Geschwind MD, Paras N. PMID: 27380339.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Convenient route to secondary sulfinates: application to the stereospecific synthesis of a-C-chiral sulfonamides. Org Lett. 2014 Dec 05; 16(23):6248-51. Johnson MG, Gribble MW, Houze JB, Paras NA. PMID: 25415837.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    11. Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline. J Med Chem. 2009 Oct 22; 52(20):6189-92. Smith AL, DeMorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. PMID: 19764794.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    12. Solid-phase synthesis of 1-substituted tetrahydroisoquinoline derivatives employing BOC-protected tetrahydroisoquinoline carboxylic acids. J Comb Chem. 2004 Jul-Aug; 6(4):487-96. Bunin BA, Dener JM, Kelly DE, Paras NA, Tario JD, Tushup SP. PMID: 15244409.
      View in: PubMed   Mentions: 3     Fields:    
    13. The enantioselective organocatalytic 1,4-addition of electron-rich benzenes to alpha,beta-unsaturated aldehydes. J Am Chem Soc. 2002 Jul 10; 124(27):7894-5. Paras NA, MacMillan DW. PMID: 12095321.
      View in: PubMed   Mentions: 14     Fields:    
    14. New strategies in organic catalysis: the first enantioselective organocatalytic Friedel-Crafts alkylation. J Am Chem Soc. 2001 May 09; 123(18):4370-1. Paras NA, MacMillan DW. PMID: 11457218.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    15. C2-Symmetric Copper(II) Complexes as Chiral Lewis Acids. Catalytic Enantioselective Carbonyl−Ene Reactions with Glyoxylate and Pyruvate Esters. Journal of the American Chemical Society. 2000; 122(33):7936-7943. David A Evans, Steven W Tregay, Christopher S Burgey, Nick A Paras, Tomas Vojkovsky. View Publication.
    16. C2-Symmetric Copper(II) Complexes as Chiral Lewis Acids. Enantioselective Catalysis of the Glyoxylate−Ene Reaction. Journal of the American Chemical Society. 1998; 120(23):5824-5825. David A Evans, Christopher S Burgey, Nick A Paras, Tomas Vojkovsky, Steven W Tregay. View Publication.
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