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Philip Sabes, PhD

TitleProfessor Emeritus
InstitutionUniversity of California San Francisco
DepartmentPhysiology
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-7372
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    Collapse Overview
    The Sabes Lab studies how the brain uses sensory feedback to maintain accurate and adaptive movement control. His lab also applies this research to the development of Brain Machine Interfaces (BMIs). They recently demonstrated a novel learning-based approach to providing artificial sensory feedback to the brain. A goal of this work is to allow users to feel artificial devices they control via BMIs. His lab is also developing neural interfaces for both next-generation studies of brain-wide sensorimotor circuits and for the combined “read out” and “write in” of BMI signals across these circuits.


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    Collapse Research Activities and Funding
    A New Scalable Approach to High Bandwidth, Minimally Invasive Neural Recording and Stimulation
    DARPA W911NF-15-2-0054Jun 15, 2015 - Sep 14, 2017
    Role: Principal Investigator
    Restoring proprioception via a cortical prosthesis: A novel learning-based approach
    CDMRP - Spinal Cord Injury Research Program W81XWH-14-1-0510Oct 1, 2014 - Sep 30, 2017
    Role: Principal Investigator
    Unlearning neural systems dysfunction in neuropsychiatric disorders
    DARPA W911NF-14-2-0043Jul 1, 2014 - Jun 3, 2019
    Role: Co-Investigato
    Visuomotor adaptation in reaching
    NIH/NEI R01EY015679Sep 1, 2004 - Jun 30, 2013
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Yazdan-Shahmorad A, Silversmith DB, Kharazia V, Sabes P. Targeted cortical reorganization using optogenetics in non-human primates. Elife. 2018 May 29; 7. PMID: 29809133.
      View in: PubMed
    2. Makin JG, O'Doherty JE, Cardoso MMB, Sabes P. Superior arm-movement decoding from cortex with a new, unsupervised-learning algorithm. J Neural Eng. 2018 Apr; 15(2):026010. PMID: 29192609.
      View in: PubMed
    3. Yazdan-Shahmorad A, Tian N, Kharazia V, Samaranch L, Kells A, Bringas J, He J, Bankiewicz K, Sabes P. Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus. J Neurosci Methods. 2018 Jan 01; 293:347-358. PMID: 29042259.
      View in: PubMed
    4. Diaz-Botia CA, Luna LE, Neely RM, Chamanzar M, Carraro C, Carmena JM, Sabes P, Maboudian R, Maharbiz MM. A silicon carbide array for electrocorticography and peripheral nerve recording. J Neural Eng. 2017 Oct; 14(5):056006. PMID: 28573982.
      View in: PubMed
    5. Chaisanguanthum KS, Shen HH, Sabes P. Neural Representation and Causal Models in Motor Cortex. J Neurosci. 2017 Mar 22; 37(12):3413-3424. PMID: 28219983.
      View in: PubMed
    6. Dadarlat MC, Sabes P. Encoding and Decoding of Multi-Channel ICMS in Macaque Somatosensory Cortex. IEEE Trans Haptics. 2016 Oct-Dec; 9(4):508-514. PMID: 27740497.
      View in: PubMed
    7. Yazdan-Shahmorad A, Diaz-Botia C, Hanson TL, Kharazia V, Ledochowitsch P, Maharbiz MM, Sabes P. A Large-Scale Interface for Optogenetic Stimulation and Recording in Nonhuman Primates. Neuron. 2016 Mar 02; 89(5):927-39. PMID: 26875625.
      View in: PubMed
    8. Makin JG, Dichter BK, Sabes P. Learning to Estimate Dynamical State with Probabilistic Population Codes. PLoS Comput Biol. 2015 Nov; 11(11):e1004554. PMID: 26540152; PMCID: PMC4634970.
    9. Ledochowitsch P, Yazdan-Shahmorad A, Bouchard KE, Diaz-Botia C, Hanson TL, He JW, Seybold BA, Olivero E, Phillips EA, Blanche TJ, Schreiner CE, Hasenstaub A, Chang EF, Sabes P, Maharbiz MM. Strategies for optical control and simultaneous electrical readout of extended cortical circuits. J Neurosci Methods. 2015 Dec 30; 256:220-31. PMID: 26296286.
      View in: PubMed
    10. Dadarlat MC, O'Doherty JE, Sabes P. A learning-based approach to artificial sensory feedback leads to optimal integration. Nat Neurosci. 2015 Jan; 18(1):138-44. PMID: 25420067; PMCID: PMC4282864.
    11. Chaisanguanthum KS, Shen HH, Sabes P. Motor variability arises from a slow random walk in neural state. J Neurosci. 2014 Sep 03; 34(36):12071-80. PMID: 25186752; PMCID: PMC4152607.
    12. Makin JG, Fellows MR, Sabes P. Learning multisensory integration and coordinate transformation via density estimation. PLoS Comput Biol. 2013 Apr; 9(4):e1003035. PMID: 23637588; PMCID: PMC3630212.
    13. Verstynen T, Sabes P. How each movement changes the next: an experimental and theoretical study of fast adaptive priors in reaching. J Neurosci. 2011 Jul 06; 31(27):10050-9. PMID: 21734297; PMCID: PMC3148097.
    14. McGuire LM, Sabes P. Heterogeneous representations in the superior parietal lobule are common across reaches to visual and proprioceptive targets. J Neurosci. 2011 May 04; 31(18):6661-73. PMID: 21543595; PMCID: PMC3100795.
    15. Sabes P. Sensory integration for reaching: models of optimality in the context of behavior and the underlying neural circuits. Prog Brain Res. 2011; 191:195-209. PMID: 21741553; PMCID: PMC3361512.
    16. McGuire LM, Sabes P. Sensory transformations and the use of multiple reference frames for reach planning. Nat Neurosci. 2009 Aug; 12(8):1056-61. PMID: 19597495; PMCID: PMC2749235.
    17. Simani MC, McGuire LM, Sabes P. Visual-shift adaptation is composed of separable sensory and task-dependent effects. J Neurophysiol. 2007 Nov; 98(5):2827-41. PMID: 17728389; PMCID: PMC2536598.
    18. Cheng S, Sabes P. Calibration of visually guided reaching is driven by error-corrective learning and internal dynamics. J Neurophysiol. 2007 Apr; 97(4):3057-69. PMID: 17202230; PMCID: PMC2536620.
    19. Cheng S, Sabes P. Modeling sensorimotor learning with linear dynamical systems. Neural Comput. 2006 Apr; 18(4):760-93. PMID: 16494690; PMCID: PMC2536592.
    20. Sober SJ, Sabes P. Flexible strategies for sensory integration during motor planning. Nat Neurosci. 2005 Apr; 8(4):490-7. PMID: 15793578; PMCID: PMC2538489.
    21. Sober SJ, Sabes P. Multisensory integration during motor planning. J Neurosci. 2003 Aug 06; 23(18):6982-92. PMID: 12904459.
      View in: PubMed
    22. Sabes P, Breznen B, Andersen RA. Parietal representation of object-based saccades. J Neurophysiol. 2002 Oct; 88(4):1815-29. PMID: 12364508.
      View in: PubMed
    23. Sabes P. The planning and control of reaching movements. Curr Opin Neurobiol. 2000 Dec; 10(6):740-6. PMID: 11240283.
      View in: PubMed
    24. Sabes P, Jordan MI, Wolpert DM. The role of inertial sensitivity in motor planning. J Neurosci. 1998 Aug 01; 18(15):5948-57. PMID: 9671681.
      View in: PubMed
    25. Sabes P, Jordan MI. Obstacle avoidance and a perturbation sensitivity model for motor planning. J Neurosci. 1997 Sep 15; 17(18):7119-28. PMID: 9278546.
      View in: PubMed
    26. Kelton KF, Gibbons PC, Sabes P. New icosahedral phases in Ti-transition-metal alloys. Phys Rev B Condens Matter. 1988 Oct 15; 38(11):7810-7813. PMID: 9945513.
      View in: PubMed