"Receptors, KIR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
| Descriptor ID |
D054340
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| MeSH Number(s) |
D12.776.543.750.705.895.500
|
| Concept/Terms |
Receptors, KIR- Receptors, KIR
- Killer Inhibitory Receptors
- Inhibitory Receptors, Killer
- Receptors, Killer Inhibitory
- Receptor, p58 NK Cell
- p58 Natural Killer Cell Receptor
- KIR Receptor
- Receptor, KIR
- p58 NK Cell Inhibitory Receptor
- Receptor, Killer Inhibitory
- Killer Inhibitory Receptor
- Inhibitory Receptor, Killer
- Killer Immunoglobulin-Like Receptor
- Immunoglobulin-Like Receptor, Killer
- Killer Immunoglobulin Like Receptor
- Receptor, Killer Immunoglobulin-Like
- Killer Cell Immunoglobulin-Like Receptor
- Killer Cell Immunoglobulin Like Receptor
- KIR Family Receptors
- Family Receptors, KIR
- Receptors, KIR Family
- KIR Receptors
- Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors
- Killer Cell Immunoglobulin-Like Receptors
- Killer Cell Immunoglobulin Like Receptors
- p58 NK Cell Receptor
- p58 NK Cell Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, KIR".
Below are MeSH descriptors whose meaning is more specific than "Receptors, KIR".
This graph shows the total number of publications written about "Receptors, KIR" by people in this website by year, and whether "Receptors, KIR" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 4 | 4 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 9 | 9 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 4 | 6 | 10 |
| 2008 | 8 | 0 | 8 |
| 2009 | 6 | 1 | 7 |
| 2010 | 3 | 1 | 4 |
| 2011 | 3 | 4 | 7 |
| 2012 | 8 | 0 | 8 |
| 2013 | 3 | 2 | 5 |
| 2014 | 4 | 3 | 7 |
| 2015 | 7 | 1 | 8 |
| 2016 | 5 | 0 | 5 |
| 2017 | 2 | 1 | 3 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 1 | 3 |
| 2021 | 6 | 2 | 8 |
| 2022 | 2 | 5 | 7 |
| 2023 | 4 | 3 | 7 |
| 2024 | 2 | 0 | 2 |
| 2025 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, KIR" by people in Profiles.
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Regulatory KIR+CD8+ T cells are elevated during human pregnancy. Sci Transl Med. 2025 Aug 06; 17(810):eadm7697.
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Impact of Human Leukocyte Antigen Allele-Killer Cell Immunoglobulin-like Receptor Partners on Sexually Transmitted Human Immunodeficiency Virus Type 1 Infection. J Infect Dis. 2024 Nov 15; 230(5):e1077-e1081.
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High-dimensional analysis of NK cells in kidney transplantation uncovers subsets associated with antibody-independent graft dysfunction. JCI Insight. 2024 Nov 08; 9(21).
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Hepatocellular carcinoma after direct-acting antivirals for hepatitis C is associated with KIR-HLA types predicting weak NK cell-mediated immunity. Eur J Immunol. 2024 Aug; 54(8):e2350678.
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HLA-DPB1*13:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID-19. HLA. 2024 01; 103(1):e15251.
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Exceptional diversity of KIR and HLA class I in Egypt. HLA. 2024 01; 103(1):e15177.
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The genotype list string code syntax for exchanging nomenclature-level genotyping results in clinical and research data management and analysis systems. HLA. 2023 10; 102(4):501-507.
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Genotype List String 1.1: Extending the Genotype List String grammar for describing HLA and Killer-cell Immunoglobulin-like Receptor genotypes. HLA. 2023 08; 102(2):206-212.
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KIR/KIR-ligand genotypes and clinical outcomes following chemoimmunotherapy in patients with relapsed or refractory neuroblastoma: a report from the Children's Oncology Group. J Immunother Cancer. 2023 02; 11(2).
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Association of KIR2DL5, KIR2DS5, and KIR2DS1 allelic variation and atopic dermatitis. Sci Rep. 2023 01 31; 13(1):1730.