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A Scan of Pleiotropic Immune Mediated Disease Genes Identifies Novel Determinants of Baseline FVIII Inhibitor Status in Hemophilia-A. Res Sq. 2023 Oct 18.
Howard T, Almieda M, Diego V, Viel K, Luu B, Haack K, Raja R, Ameri A, Chitlur M, Rydz N, Lillicrap D, Watts R, Kessler C, Ramsey C, Dinh L, Kim B, Powell J, Peralta J, Bouls R, Abraham S, Shen YM, Murillo C, Mead H, Lehmann P, Fine E, Escobar M, Kumar S, Williams-Blangero S, Kasper C, Almasy L, Cole S, Blangero J, Konkle B. PMID: 37886476; PMCID: PMC10602130.
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PubMed Mentions:
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COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted renal transplant candidates- a multicenter cohort. Hum Immunol. 2023 Apr; 84(4):278-285.
Roll GR, Bray RA, Cooper M, Eagar TN, Gebel HM, Vranic GM, Hitchman KMK, Houp J, Kamoun M, Killian J, Kim J, Kumar V, Levine M, Lovasik BP, Lunow-Luke T, Parsons RF, Pattanayak V, Ranch D, Shah A, Stock PG, Timofeeva OA, Trofe-Clark J, Wongjirad C, Yeh H, Yi S, Rajalingam R. PMID: 36868898; PMCID: PMC9946887.
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PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
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Experimental and clinical data analysis for identification of COVID-19 resistant ACE2 mutations. Sci Rep. 2023 02 09; 13(1):2351.
Raghav PK, Raghav A, Lathwal A, Saxena A, Mann Z, Sengar M, Rajalingam R. PMID: 36759535; PMCID: PMC9910265.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses. bioRxiv. 2023 Jan 20.
Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Eun-Hyung Lee F. PMID: 36711623; PMCID: PMC9882341.
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PubMed Mentions:
-
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression. Nat Biotechnol. 2023 05; 41(5):717-727.
Gravina A, Tediashvili G, Rajalingam R, Quandt Z, Deisenroth C, Schrepfer S, Deuse T. PMID: 36593395; PMCID: PMC10188358.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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KIR-HLA gene diversities and susceptibility to lung cancer. Sci Rep. 2022 10 14; 12(1):17237.
Hematian Larki M, Ashouri E, Barani S, Ghayumi SMA, Ghaderi A, Rajalingam R. PMID: 36241658; PMCID: PMC9568660.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19. Front Genet. 2022; 13:845474.
Maruthamuthu S, Rajalingam K, Kaur N, Morvan MG, Soto J, Lee N, Kong D, Hu Z, Reyes K, Ng D, Butte AJ, Chiu C, Rajalingam R. PMID: 35273641; PMCID: PMC8902362.
View in:
PubMed Mentions:
12
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Concurrent use of two independent methods prevents erroneous HLA typing of deceased organ donors - An important strategy for patient safety and accurate virtual crossmatching for broader sharing. Hum Immunol. 2022 May; 83(5):458-466.
Cruz TD, Dames C, Pagaduan L, Cho Y, Kong D, Rajalingam R. PMID: 35193787.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Solid-Phase C1q/C3d Fixing Readouts Correlate with High Median Fluorescence Intensity (MFI) De Novo Donor-Specific HLA Antibodies and C4d⁺ Antibody-Mediated Rejection in Kidney Transplant Recipients. Ann Transplant. 2021 Dec 01; 26:e934175.
Tatapudi VS, Kopchaliiska D, da Gente GJ, Buenaventura OF, Singh M, Laszik Z, Adey DB, Rajalingam R. PMID: 34848674; PMCID: PMC8647455.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Individualized genetic makeup that controls natural killer cell function influences the efficacy of isatuximab immunotherapy in patients with multiple myeloma. J Immunother Cancer. 2021 07; 9(7).
Sun H, Martin TG, Marra J, Kong D, Keats J, Macé S, Chiron M, Wolf JL, Venstrom JM, Rajalingam R. PMID: 34272304; PMCID: PMC8287616.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Concurrent typing of over 4000 samples by long-range PCR amplicon-based NGS and rSSO revealed the need to verify NGS typing for HLA allelic dropouts. Hum Immunol. 2021 Aug; 82(8):581-587.
Kong D, Lee N, Dela Cruz ID, Dames C, Maruthamuthu S, Golden T, Rajalingam R. PMID: 33980471.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
COVID-19 does not impact HLA antibody profile in a series of waitlisted renal transplant candidates. Hum Immunol. 2021 Aug; 82(8):568-573.
Roll GR, Lunow-Luke T, Braun HJ, Buenaventura O, Mallari M, Stock PG, Rajalingam R. PMID: 33910707; PMCID: PMC8052475.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Coexistence of inhibitory and activating killer-cell immunoglobulin-like receptors to the same cognate HLA-C2 and Bw4 ligands confer breast cancer risk. Sci Rep. 2021 04 12; 11(1):7932.
Ashouri E, Rajalingam K, Barani S, Farjadian S, Ghaderi A, Rajalingam R. PMID: 33846431; PMCID: PMC8041876.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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A Virtual Crossmatch-based Strategy Facilitates Sharing of Deceased Donor Kidneys for Highly Sensitized Recipients. Transplantation. 2020 06; 104(6):1239-1245.
Roll GR, Webber AB, Gae DH, Laszik Z, Tavakol M, Mayen L, Cunniffe K, Syed S, Hirose R, Freise C, Feng S, Roberts JP, Ascher NL, Stock PG, Rajalingam R. PMID: 31449187.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Allele-level HLA matching reduces early rejection in lung transplant recipients. Ann Transl Med. 2020 Mar; 8(6):275.
Rajalingam R. PMID: 32355719; PMCID: PMC7186615.
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PubMed Mentions:
1
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Quantitative HLA-class-II/factor VIII (FVIII) peptidomic variation in dendritic cells correlates with the immunogenic potential of therapeutic FVIII proteins in hemophilia A. J Thromb Haemost. 2020 01; 18(1):201-216.
Diego VP, Luu BW, Hofmann M, Dinh LV, Almeida M, Powell JS, Rajalingam R, Peralta JM, Kumar S, Curran JE, Sauna ZE, Kellerman R, Park Y, Key NS, Escobar MA, Huynh H, Verhagen AM, Williams-Blangero S, Lehmann PV, Maraskovsky E, Blangero J, Howard TE. PMID: 31556206.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans. Nat Biotechnol. 2019 10; 37(10):1137-1144.
Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, Weissman IL, Schrepfer S. PMID: 31427818.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Long-Term Safety, Immunologic Response, and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease. Stem Cell Reports. 2019 08 13; 13(2):254-261.
Gupta N, Henry RG, Kang SM, Strober J, Lim DA, Ryan T, Perry R, Farrell J, Ulman M, Rajalingam R, Gage A, Huhn SL, Barkovich AJ, Rowitch DH. PMID: 31378671; PMCID: PMC6700500.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: guidelines from the NMDP/CIBMTR. Blood. 2019 09 19; 134(12):924-934.
Dehn J, Spellman S, Hurley CK, Shaw BE, Barker JN, Burns LJ, Confer DL, Eapen M, Fernandez-Vina M, Hartzman R, Maiers M, Marino SR, Mueller C, Perales MA, Rajalingam R, Pidala J. PMID: 31292117; PMCID: PMC6753623.
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PubMed Mentions:
95 Fields:
Translation:
Humans
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Gene signatures common to allograft rejection are associated with lymphocytic bronchitis. Clin Transplant. 2019 05; 33(5):e13515.
Greenland JR, Wang P, Brotman JJ, Ahuja R, Chong TA, Kleinhenz ME, Leard LE, Golden JA, Hays SR, Kukreja J, Singer JP, Rajalingam R, Jones K, Laszik ZG, Trivedi NN, Greenland NY, Blanc PD. PMID: 30849195; PMCID: PMC6545574.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Association of HLA Antigen Mismatch With Risk of Developing Skin Cancer After Solid-Organ Transplant. JAMA Dermatol. 2019 03 01; 155(3):307-314.
Gao Y, Twigg AR, Hirose R, Roll GR, Nowacki AS, Maytin EV, Vidimos AT, Rajalingam R, Arron ST. PMID: 30673077; PMCID: PMC6439929.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Diversity of Killer Cell Immunoglobulin-Like Receptors and Disease. Clin Lab Med. 2018 12; 38(4):637-653.
Rajalingam R. PMID: 30420058.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Inhibitory natural killer cell receptor KIR3DL1 with its ligand Bw4 constraints HIV-1 disease among South Indians. AIDS. 2018 11 28; 32(18):2679-2688.
Maruthamuthu S, Rajalingam R, Pandian K, Madasamy S, Manoharan M, Pitchai L, Murugesan A, Mariakuttikan J. PMID: 30289808.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Genotypes associated with tacrolimus pharmacokinetics impact clinical outcomes in lung transplant recipients. Clin Transplant. 2018 08; 32(8):e13332.
Calabrese DR, Florez R, Dewey K, Hui C, Torgerson D, Chong T, Faust H, Rajalingam R, Hays SR, Golden JA, Kukreja J, Singer JP, Greenland JR. PMID: 29920787; PMCID: PMC8103920.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy. J Exp Med. 2018 01 02; 215(1):141-157.
Chheda ZS, Kohanbash G, Okada K, Jahan N, Sidney J, Pecoraro M, Yang X, Carrera DA, Downey KM, Shrivastav S, Liu S, Lin Y, Lagisetti C, Chuntova P, Watchmaker PB, Mueller S, Pollack IF, Rajalingam R, Carcaboso AM, Mann M, Sette A, Garcia KC, Hou Y, Okada H. PMID: 29203539; PMCID: PMC5748856.
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PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation. J Clin Oncol. 2017 07 10; 35(20):2268-2278.
Boudreau JE, Giglio F, Gooley TA, Stevenson PA, Le Luduec JB, Shaffer BC, Rajalingam R, Hou L, Hurley CK, Noreen H, Reed EF, Yu N, Vierra-Green C, Haagenson M, Malkki M, Petersdorf EW, Spellman S, Hsu KC. PMID: 28520526; PMCID: PMC5501362.
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PubMed Mentions:
73 Fields:
Translation:
HumansCells
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HLA Mismatching Favoring Host-Versus-Graft NK Cell Activity Via KIR3DL1 Is Associated With Improved Outcomes Following Lung Transplantation. Am J Transplant. 2017 Aug; 17(8):2192-2199.
Greenland JR, Sun H, Calabrese D, Chong T, Singer JP, Kukreja J, Hays SR, Golden JA, Caughey GH, Venstrom JM, Rajalingam R. PMID: 28375571; PMCID: PMC5519429.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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The Impact of HLA Class I-Specific Killer Cell Immunoglobulin-Like Receptors on Antibody-Dependent Natural Killer Cell-Mediated Cytotoxicity and Organ Allograft Rejection. Front Immunol. 2016; 7:585.
Rajalingam R. PMID: 28066408; PMCID: PMC5165035.
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PubMed Mentions:
16 Fields:
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Donor-Reactive Regulatory T Cell Frequency Increases During Acute Cellular Rejection of Lung Allografts. Transplantation. 2016 10; 100(10):2090-8.
Greenland JR, Wong CM, Ahuja R, Wang AS, Uchida C, Golden JA, Hays SR, Leard LE, Rajalingam R, Singer JP, Kukreja J, Wolters PJ, Caughey GH, Tang Q. PMID: 27077597; PMCID: PMC5030122.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing. Am J Hum Genet. 2016 Aug 04; 99(2):375-91.
Norman PJ, Hollenbach JA, Nemat-Gorgani N, Marin WM, Norberg SJ, Ashouri E, Jayaraman J, Wroblewski EE, Trowsdale J, Rajalingam R, Oksenberg JR, Chiaroni J, Guethlein LA, Traherne JA, Ronaghi M, Parham P. PMID: 27486779; PMCID: PMC4974113.
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PubMed Mentions:
91 Fields:
Translation:
Humans
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KIR and HLA Genotypes Implicated in Reduced Killer Lymphocytes Immunity Are Associated with Vogt-Koyanagi-Harada Disease. PLoS One. 2016; 11(8):e0160392.
Levinson RD, Yung M, Meguro A, Ashouri E, Yu F, Mizuki N, Ohno S, Rajalingam R. PMID: 27490240; PMCID: PMC4973954.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Donor-Recipient Matching for KIR Genotypes Reduces Chronic GVHD and Missing Inhibitory KIR Ligands Protect against Relapse after Myeloablative, HLA Matched Hematopoietic Cell Transplantation. PLoS One. 2016; 11(6):e0158242.
Faridi RM, Kemp TJ, Dharmani-Khan P, Lewis V, Tripathi G, Rajalingam R, Daly A, Berka N, Storek J, Masood Khan F. PMID: 27341514; PMCID: PMC4920429.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1-Dependent IGF-1 Signaling. Cancer Res. 2016 05 01; 76(9):2687-97.
Sun H, Lin DC, Cao Q, Guo X, Marijon H, Zhao Z, Gery S, Xu L, Yang H, Pang B, Lee VK, Lim HJ, Doan N, Said JW, Chu P, Mayakonda A, Thomas T, Forscher C, Baloglu E, Shacham S, Rajalingam R, Koeffler HP. PMID: 26956669.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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HLA Markers DQ8 and DR53 Are Associated With Lymphocytic Hypophysitis and May Aid in Differential Diagnosis. J Clin Endocrinol Metab. 2015 Nov; 100(11):4092-7.
Heaney AP, Sumerel B, Rajalingam R, Bergsneider M, Yong WH, Liau LM. PMID: 26317559.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. J Immunol. 2014 Jul 15; 193(2):940-9.
Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. PMID: 24935928; PMCID: PMC4096688.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Characterization of human killer immunoglobulin-like receptors (KIRs) among healthy Saudis. Hum Immunol. 2014 Jun; 75(6):536-40.
Osman AE, Mubasher M, ElSheikh NE, AlHarthi H, Al Yami AS, Rajalingam R, Al-Dehaimi A, Middleton D, ElGhazali G. PMID: 24613458.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Gene-specific PCR typing of killer cell immunoglobulin-like receptors. Methods Mol Biol. 2013; 1034:239-55.
Rajalingam R, Ashouri E. PMID: 23775740.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals. PLoS One. 2012; 7(11):e47491.
Vierra-Green C, Roe D, Hou L, Hurley CK, Rajalingam R, Reed E, Lebedeva T, Yu N, Stewart M, Noreen H, Hollenbach JA, Guethlein LA, Wang T, Spellman S, Maiers M. PMID: 23139747; PMCID: PMC3489906.
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PubMed Mentions:
49 Fields:
Translation:
Humans
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Observations regarding the immunogenicity of BDD-rFVIII derived from a mechanistic personalized medicine perspective. J Thromb Haemost. 2012 Sep; 10(9):1961-5.
Sauna ZE, Ameri A, Kim B, Yanover C, Viel KR, Rajalingam R, Cole SA, Howard TE. PMID: 22734827.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Overview of the killer cell immunoglobulin-like receptor system. Methods Mol Biol. 2012; 882:391-414.
Rajalingam R. PMID: 22665247.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Human diversity of killer cell immunoglobulin-like receptors and disease. Korean J Hematol. 2011 Dec; 46(4):216-28.
Rajalingam R. PMID: 22259627; PMCID: PMC3259513.
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PubMed Mentions:
31
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The shaping of modern human immune systems by multiregional admixture with archaic humans. Science. 2011 Oct 07; 334(6052):89-94.
Abi-Rached L, Jobin MJ, Kulkarni S, McWhinnie A, Dalva K, Gragert L, Babrzadeh F, Gharizadeh B, Luo M, Plummer FA, Kimani J, Carrington M, Middleton D, Rajalingam R, Beksac M, Marsh SG, Maiers M, Guethlein LA, Tavoularis S, Little AM, Green RE, Norman PJ, Parham P. PMID: 21868630; PMCID: PMC3677943.
View in:
PubMed Mentions:
191 Fields:
Translation:
HumansAnimalsCells
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Comparison of KIR gene content profiles revealed a difference between northern and southern Persians in the distribution of KIR2DS5 and its linked loci. Hum Immunol. 2011 Nov; 72(11):1079-83.
Solgi G, Ghafari H, Ashouri E, Alimoghdam K, Rajalingam R, Amirzargar A. PMID: 21867738.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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KIR-HLA mismatching in human renal allograft transplantation: emergence of a new concept. Am J Transplant. 2011 Sep; 11(9):1771-2.
Rajalingam R, Gebel HM. PMID: 21714847.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Immunogenetics as a tool in anthropological studies. Immunology. 2011 Jun; 133(2):143-64.
Sanchez-Mazas A, Fernandez-Viña M, Middleton D, Hollenbach JA, Buhler S, Di D, Rajalingam R, Dugoujon JM, Mack SJ, Thorsby E. PMID: 21480890; PMCID: PMC3088978.
View in:
PubMed Mentions:
41 Fields:
Translation:
Humans
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HLA-DRB1*0102 is associated with TINU syndrome and bilateral, sudden-onset anterior uveitis but not with interstitial nephritis alone. Br J Ophthalmol. 2011 Jul; 95(7):971-5.
Mackensen F, David F, Schwenger V, Smith LK, Rajalingam R, Levinson RD, Austin CR, Houghton D, Martin TM, Rosenbaum JT. PMID: 21059595.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
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Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells. PLoS Genet. 2010 Nov 04; 6(11):e1001192.
Abi-Rached L, Moesta AK, Rajalingam R, Guethlein LA, Parham P. PMID: 21079681; PMCID: PMC2973822.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals. Hum Immunol. 2010 Feb; 71(2):192-4.
Levinson RD, Okada AA, Ashouri E, Keino H, Rajalingam R. PMID: 19897003.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis. Hum Immunol. 2010 Feb; 71(2):212-9.
Bonagura VR, Du Z, Ashouri E, Luo L, Hatam LJ, DeVoti JA, Rosenthal DW, Steinberg BM, Abramson AL, Gjertson DW, Reed EF, Rajalingam R. PMID: 19861144; PMCID: PMC2815039.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1505-10.
Levinson RD, Martin TM, Luo L, Ashouri E, Rosenbaum JT, Smith JR, Austin CR, Lutt JR, Rajalingam R. PMID: 19850842; PMCID: PMC2868435.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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KIR gene content diversity in four Iranian populations. Immunogenetics. 2009 Jul; 61(7):483-92.
Ashouri E, Farjadian S, Reed EF, Ghaderi A, Rajalingam R. PMID: 19521696; PMCID: PMC2706385.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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A novel duplex SSP-PCR typing method for KIR gene profiling. Tissue Antigens. 2009 Jul; 74(1):62-7.
Ashouri E, Ghaderi A, Reed EF, Rajalingam R. PMID: 19392793.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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A novel real-time PCR method for KIR genotyping. Tissue Antigens. 2009 Feb; 73(2):188-91.
Alves LG, Rajalingam R, Canavez F. PMID: 19140829.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians. Int J Immunogenet. 2008 Dec; 35(6):439-46.
Shastry A, Sedimbi SK, Rajalingam R, Nikitina-Zake L, Rumba I, Wigzell H, Sanjeevi CB. PMID: 19046302.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations. Ann N Y Acad Sci. 2008 Dec; 1150:133-8.
Shastry A, Sedimbi SK, Rajalingam R, Rumba I, Kanungo A, Sanjeevi CB. PMID: 19120281.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Variable interactions of recipient killer cell immunoglobulin-like receptors with self and allogenic human leukocyte antigen class I ligands may influence the outcome of solid organ transplants. Curr Opin Organ Transplant. 2008 Aug; 13(4):430-7.
Rajalingam R. PMID: 18685341.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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KIR2DL5 alleles mark certain combination of activating KIR genes. Genes Immun. 2008 Jul; 9(5):470-80.
Du Z, Sharma SK, Spellman S, Reed EF, Rajalingam R. PMID: 18509341.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease. Hum Immunol. 2008 Jun; 69(6):349-53.
Levinson RD, Du Z, Luo L, Holland GN, Rao NA, Reed EF, Rajalingam R. PMID: 18571006.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Distinct diversity of KIR genes in three southern Indian populations: comparison with world populations revealed a link between KIR gene content and pre-historic human migrations. Immunogenetics. 2008 May; 60(5):207-17.
Rajalingam R, Du Z, Meenagh A, Luo L, Kavitha VJ, Pavithra-Arulvani R, Vidhyalakshmi A, Sharma SK, Balazs I, Reed EF, Pitchappan RM, Middleton D. PMID: 18369612.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
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Comparison of the rapidly evolving KIR locus in Parsis and natives of India. Immunogenetics. 2008 Apr; 60(3-4):121-9.
Kulkarni S, Single RM, Martin MP, Rajalingam R, Badwe R, Joshi N, Carrington M. PMID: 18351333.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals. Genes Immun. 2008 Apr; 9(3):249-58.
Levinson RD, Du Z, Luo L, Monnet D, Tabary T, Brezin AP, Zhao L, Gjertson DW, Holland GN, Reed EF, Cohen JH, Rajalingam R. PMID: 18340360.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Chain-terminating natural mutations affect the function of activating KIR receptors 3DS1 and 2DS3. Immunogenetics. 2007 Oct; 59(10):779-92.
Luo L, Du Z, Sharma SK, Cullen R, Spellman S, Reed EF, Rajalingam R. PMID: 17646980.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Killer cell immunoglobulin-like receptors influence the innate and adaptive immune responses. Iran J Immunol. 2007 Jun; 4(2):61-78.
Rajalingam R. PMID: 17652846.
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6 Fields:
Translation:
HumansCells
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Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans. Immunogenetics. 2007 Jan; 59(1):1-15.
Du Z, Gjertson DW, Reed EF, Rajalingam R. PMID: 17103212.
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PubMed Mentions:
40 Fields:
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HumansCells
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HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California. Hum Immunol. 2004 Dec; 65(12):1477-82.
Levinson RD, See RF, Rajalingam R, Reed EF, Park MS, Rao NA, Holland GN. PMID: 15603876.
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14 Fields:
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Humans
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Human leukocyte antigen A29 subtypes associated with birdshot retinochoroidopathy. Am J Ophthalmol. 2004 Oct; 138(4):631-4.
Levinson RD, Rajalingam R, Park MS, Reed EF, Gjertson DW, Kappel PJ, See RF, Rao NA, Holland GN. PMID: 15488792.
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PubMed Mentions:
12 Fields:
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Humans
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A sequencing-based typing method for HLA-DQA1 alleles. Hum Immunol. 2004 Apr; 65(4):373-9.
Rajalingam R, Ge P, Reed EF. PMID: 15120193.
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4 Fields:
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Humans
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Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells. Hum Immunol. 2004 Apr; 65(4):291-302.
Jin YP, Fishbein MC, Said JW, Jindra PT, Rajalingam R, Rozengurt E, Reed EF. PMID: 15120184.
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48 Fields:
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HumansCells
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Domain shuffling has been the main mechanism forming new hominoid killer cell Ig-like receptors. J Immunol. 2004 Jan 01; 172(1):356-69.
Rajalingam R, Parham P, Abi-Rached L. PMID: 14688344.
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56 Fields:
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HumansAnimalsCells
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Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression. Immunogenetics. 2002 Nov; 54(8):543-50.
Yawata M, Yawata N, McQueen KL, Cheng NW, Guethlein LA, Rajalingam R, Shilling HG, Parham P. PMID: 12439616.
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58 Fields:
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HumansCells
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Distinctive KIR and HLA diversity in a panel of north Indian Hindus. Immunogenetics. 2002 Mar; 53(12):1009-19.
Rajalingam R, Krausa P, Shilling HG, Stein JB, Balamurugan A, McGinnis MD, Cheng NW, Mehra NK, Parham P. PMID: 11904677.
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PubMed Mentions:
40 Fields:
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Humans
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Conservation and variation in human and common chimpanzee CD94 and NKG2 genes. J Immunol. 2002 Jan 01; 168(1):240-52.
Shum BP, Flodin LR, Muir DG, Rajalingam R, Khakoo SI, Cleland S, Guethlein LA, Uhrberg M, Parham P. PMID: 11751968.
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PubMed Mentions:
41 Fields:
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HumansAnimalsCells
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Comparison of chimpanzee and human leukocyte Ig-like receptor genes reveals framework and rapidly evolving genes. J Immunol. 2001 Nov 15; 167(10):5786-94.
Canavez F, Young NT, Guethlein LA, Rajalingam R, Khakoo SI, Shum BP, Parham P. PMID: 11698452.
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PubMed Mentions:
21 Fields:
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HumansAnimalsCells
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Molecular diversity of HLA-A*02 in Asian Indians: predominance of A*0211. Tissue Antigens. 2001 Jun; 57(6):502-7.
Mehra NK, Jaini R, Rajalingam R, Balamurugan A, Kaur G. PMID: 11556980.
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PubMed Mentions:
12 Fields:
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HumansCells
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Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism. J Immunol. 2001 Mar 01; 166(5):2992-3001.
Gardiner CM, Guethlein LA, Shilling HG, Pando M, Carr WH, Rajalingam R, Vilches C, Parham P. PMID: 11207248.
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PubMed Mentions:
110 Fields:
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HumansCells
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Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors. Tissue Antigens. 2001 Jan; 57(1):22-31.
Rajalingam R, Gardiner CM, Canavez F, Vilches C, Parham P. PMID: 11169255.
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PubMed Mentions:
12 Fields:
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HumansCells
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Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes. J Exp Med. 2001 Jan 01; 193(1):135-46.
Rajalingam R, Hong M, Adams EJ, Shum BP, Guethlein LA, Parham P. PMID: 11136827; PMCID: PMC2195888.
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32 Fields:
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HumansAnimalsCells
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Discovery of two novel variants of KIR2DS5 reveals this gene to be a common component of human KIR 'B' haplotypes. Tissue Antigens. 2000 Nov; 56(5):453-6.
Vilches C, Pando MJ, Rajalingam R, Gardiner CM, Parham P. PMID: 11144295.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Polymorphism in heat-shock protein 70-1 (HSP70-1) gene promoter region and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians. Indian J Exp Biol. 2000 Jul; 38(7):658-62.
Rajalingam R, Mehra NK, Singal DP. PMID: 11215307.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Cold reactive lymphocytotoxic antibodies in pulmonary tuberculosis: correlation with disease activity and HLA. Indian J Exp Biol. 2000 Jul; 38(7):643-50.
Rajalingam R, Mehra NK, Jain RC. PMID: 11215305.
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HumansCells
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KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains. J Immunol. 2000 Jun 01; 164(11):5797-804.
Vilches C, Rajalingam R, Uhrberg M, Gardiner CM, Young NT, Parham P. PMID: 10820258.
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PubMed Mentions:
32 Fields:
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HumansAnimalsCells
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Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans. Immunity. 2000 Jun; 12(6):687-98.
Khakoo SI, Rajalingam R, Shum BP, Weidenbach K, Flodin L, Muir DG, Canavez F, Cooper SL, Valiante NM, Lanier LL, Parham P. PMID: 10894168.
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PubMed Mentions:
94 Fields:
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HumansAnimalsCells
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A divergent non-classical class I gene conserved in salmonids. Immunogenetics. 1999 Jun; 49(6):479-90.
Shum BP, Rajalingam R, Magor KE, Azumi K, Carr WH, Dixon B, Stet RJ, Adkison MA, Hedrick RP, Parham P. PMID: 10380691.
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PubMed Mentions:
29 Fields:
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HumansAnimalsCells
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Polymorphic MHC molecules dictate cytokine profile and clinical disease in mycobacterial diseases. Indian J Clin Biochem. 1997 Dec; 12(Suppl 1):100.
Mehra NK, Mitra DK, Rajalingam R. PMID: 23100914; PMCID: PMC3454303.
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HLA class I profile in Asian Indian patients with pulmonary tuberculosis. Indian J Exp Biol. 1997 Oct; 35(10):1055-9.
Rajalingam R, Mehra NK, Mehra RD, Neolia S, Jain RC, Pande JN. PMID: 9475039.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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HLA association and occurrence of autoantibodies in Asian-Indian patients with ulcerative colitis. Am J Gastroenterol. 1997 May; 92(5):772-6.
Habeeb MA, Rajalingam R, Dhar A, Kumar A, Sharma MP, Mehra NK. PMID: 9149183.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Transporter associated with antigen-processing (TAP) genes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis. Tissue Antigens. 1997 Feb; 49(2):168-72.
Rajalingam R, Singal DP, Mehra NK. PMID: 9062973.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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HLA-DR polymorphism modulates the cytokine profile of Mycobacterium leprae HSP-reactive CD4+ T cells. Clin Immunol Immunopathol. 1997 Jan; 82(1):60-7.
Mitra DK, Rajalingam R, Taneja V, Bhattacharyya BC, Mehra NK. PMID: 9000043.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Anti-IgG autoantibodies and possible immune regulatory mechanisms in patients with pulmonary tuberculosis. Tuber Lung Dis. 1996 Dec; 77(6):502-9.
Rajalingam R, Mehra NK, Chopra GS, Puri MM, Jain RC. PMID: 9039442.
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HumansCells
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Direct role of HLA-B5 in influencing susceptibility to Takayasu aortoarteritis. Int J Cardiol. 1996 Aug; 54 Suppl:S71-9.
Mehra NK, Rajalingam R, Sagar S, Jain S, Sharma BK. PMID: 9119529.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Correlation of serum interleukin-2 receptor-alpha levels with clinical manifestations in pulmonary tuberculosis. Tuber Lung Dis. 1996 Aug; 77(4):374-9.
Rajalingam R, Mehra NK, Pande JN, Jain RC, Singla R. PMID: 8796256.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Polymerase chain reaction--based sequence-specific oligonucleotide hybridization analysis of HLA class II antigens in pulmonary tuberculosis: relevance to chemotherapy and disease severity. J Infect Dis. 1996 Mar; 173(3):669-76.
Rajalingam R, Mehra NK, Jain RC, Myneedu VP, Pande JN. PMID: 8627031.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Generation of DR51-associated DQA1, DQB1 haplotypes in Asian Indians. Tissue Antigens. 1996 Jan; 47(1):85-9.
Mehra NK, Rajalingam R, Giphart MJ. PMID: 8929717.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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CD4+ T-cell responses to recombinant hsp65 and hsp18 of M. leprae and their trypsin-digested fragments in leprosy: diversity in HLA-DR restriction. Int J Lepr Other Mycobact Dis. 1995 Dec; 63(4):518-28.
Mitra DK, Mehra NK, Maiti TK, Banerjee A, Taneja V, Rajalingam R, Ahuja RK, Bhattacharya BC. PMID: 8642214.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Variants of HLA-DR2/DR51 group haplotypes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians. Int J Lepr Other Mycobact Dis. 1995 Jun; 63(2):241-8.
Mehra NK, Rajalingam R, Mitra DK, Taneja V, Giphart MJ. PMID: 7602219.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Dorsolateral prostatic phosphomonoesterases and adenosine triphosphatases in hypo- and hyperthyroid rats. Indian J Exp Biol. 1994 Sep; 32(9):616-8.
Sidharthan V, Rose PJ, Rajalingam R, Udhayakumar RC, Aruldhas MM, Govindarajulu P. PMID: 7814039.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Asian Indian HLA-DR2-, DR4-, and DR52-related DR-DQ genotypes analyzed by polymerase chain reaction based nonradioactive oligonucleotide typing. Unique haplotypes and a novel DR4 subtype. Hum Immunol. 1994 Mar; 39(3):202-10.
Mehra NK, Bouwens AG, Naipal A, Rajalingam R, Grubic Z, Taneja V, Tilanus MG, Giphart MJ. PMID: 8026988.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Effects of alloxan induced diabetes on lipid profiles in renal cortex and medulla of mature albino rats. Indian J Exp Biol. 1993 Jun; 31(6):577-9.
Rajalingam R, Srinivasan N, Govindarajulu P. PMID: 8406610.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Ventral prostatic phosphomonoesterases and adenosine triphosphatases in hypo- and hyperthyroid albino rats. Indian J Exp Biol. 1993 May; 31(5):414-6.
Sidharthan V, Rajalingam R, Aruldhas MM, Govindarajulu P. PMID: 8395467.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Human leukocyte antigen (HLA) in respiratory allergy. Asian Pac J Allergy Immunol. 1992 Dec; 10(2):151-8.
Mehra NK, Rajalingam R, Bovornkitti S. PMID: 1305817.
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Translation:
Humans