Qinheng Zheng, PhD

Title(s)Postdoctoral Scholar, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Address600 16th Street, #N514
San Francisco CA 94158
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-8440-8673 Additional info
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    Collapse Biography 
    Collapse Education and Training
    The Scripps Research Institute, La Jolla, CAPhD05/2020Chemistry
    Peking University, Beijing, ChinaBS07/2014Chemistry

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nat Chem Biol. 2024 Sep; 20(9):1114-1122. Zheng Q, Zhang Z, Guiley KZ, Shokat KM. PMID: 38443470; PMCID: PMC11357986.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    2. Drugging the Next Undruggable KRAS Allele-Gly12Asp. J Med Chem. 2022 02 24; 65(4):3119-3122. Zheng Q, Peacock DM, Shokat KM. PMID: 35167298.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    3. Sulfur [18F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis. J Am Chem Soc. 2021 03 17; 143(10):3753-3763. Zheng Q, Xu H, Wang H, Du WH, Wang N, Xiong H, Gu Y, Noodleman L, Sharpless KB, Yang G, Wu P. PMID: 33630577; PMCID: PMC8418205.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    4. Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry. J Am Chem Soc. 2020 06 24; 142(25):10899-10904. Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. PMID: 32479075; PMCID: PMC7751259.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    5. SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):18808-18814. Zheng Q, Woehl JL, Kitamura S, Santos-Martins D, Smedley CJ, Li G, Forli S, Moses JE, Wolan DW, Sharpless KB. PMID: 31484779; PMCID: PMC6754619.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    6. The growing applications of SuFEx click chemistry. Chem Soc Rev. 2019; 48:4731-4758. Barrow AS, Smedley CJ, Zheng Q, Li S, Dong J, Moses JE. View Publication.
    7. Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angew Chem Int Ed Engl. 2019 03 26; 58(14):4552-4556. Smedley CJ, Zheng Q, Gao B, Li S, Molino A, Duivenvoorden HM, Parker BS, Wilson DJD, Sharpless KB, Moses JE. PMID: 30740848.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    8. Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry. 2018 Jul 20; 24(41):10550-10556. Gahtory D, Sen R, Pujari S, Li S, Zheng Q, Moses JE, Sharpless KB, Zuilhof H. PMID: 29949211; PMCID: PMC6099289.
      View in: PubMed   Mentions: 17     Fields:    
    9. Bifluoride-catalysed sulfur(VI) fluoride exchange reaction for the synthesis of polysulfates and polysulfonates. Nat Chem. 2017 11; 9(11):1083-1088. Gao B, Zhang L, Zheng Q, Zhou F, Klivansky LM, Lu J, Liu Y, Dong J, Wu P, Sharpless KB. PMID: 29064495; PMCID: PMC5972039.
      View in: PubMed   Mentions: 57     Fields:    Translation:Cells
    10. SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts. Angew Chem Int Ed Engl. 2017 09 04; 56(37):11203-11208. Wang H, Zhou F, Ren G, Zheng Q, Chen H, Gao B, Klivansky L, Liu Y, Wu B, Xu Q, Lu J, Sharpless KB, Wu P. PMID: 28792119; PMCID: PMC5665377.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    11. Palladium-Catalyzed Fluorosulfonylvinylation of Organic Iodides. Angew Chem Int Ed Engl. 2017 04 18; 56(17):4849-4852. Zha GF, Zheng Q, Leng J, Wu P, Qin HL, Sharpless KB. PMID: 28370917; PMCID: PMC5653204.
      View in: PubMed   Mentions: 20     Fields:    
    12. Aryl Fluorosulfate Trapped Staudinger Reduction. Org Lett. 2017 04 07; 19(7):1582-1585. Ren G, Zheng Q, Wang H. PMID: 28332844; PMCID: PMC5922792.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    13. Ethenesulfonyl Fluoride (ESF): An On-Water Procedure for the Kilogram-Scale Preparation. J Org Chem. 2016 11 18; 81(22):11360-11362. Zheng Q, Dong J, Sharpless KB. PMID: 27764941.
      View in: PubMed   Mentions: 19     Fields:    
    14. A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry. Angew Chem Int Ed Engl. 2016 11 02; 55(45):14155-14158. Qin HL, Zheng Q, Bare GA, Wu P, Sharpless KB. PMID: 27723200; PMCID: PMC5102157.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    15. Mild-condition synthesis of allenes from alkynes and aldehydes mediated by tetrahydroisoquinoline (THIQ). J Org Chem. 2013 Dec 06; 78(23):11783-93. Jiang GJ, Zheng QH, Dou M, Zhuo LG, Meng W, Yu ZX. PMID: 24266693.
      View in: PubMed   Mentions: 1     Fields:    
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