Qinheng Zheng • UCSF Profiles

Qinheng Zheng, PhD

Title(s)	Postdoctoral Scholar, Cellular Molecular Pharmacology
School	School of Medicine
Address	600 16th Street, #N514 San Francisco CA 94158
ORCID	0000-0002-8440-8673
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Biography

Education and Training

The Scripps Research Institute, La Jolla, CA	PhD	05/2020	Chemistry
Peking University, Beijing, China	BS	07/2014	Chemistry

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nat Chem Biol. 2024 Sep; 20(9):1114-1122. Zheng Q, Zhang Z, Guiley KZ, Shokat KM. PMID: 38443470; PMCID: PMC11357986.

View in: PubMed Mentions: 5 Fields:
Bio Biology Che Chemistry
Translation:Humans Animals Cells
Drugging the Next Undruggable KRAS Allele-Gly12Asp. J Med Chem. 2022 02 24; 65(4):3119-3122. Zheng Q, Peacock DM, Shokat KM. PMID: 35167298.

View in: PubMed Mentions: 12 Fields:
Che Chemistry
Translation:Humans Animals
Sulfur [18F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis. J Am Chem Soc. 2021 03 17; 143(10):3753-3763. Zheng Q, Xu H, Wang H, Du WH, Wang N, Xiong H, Gu Y, Noodleman L, Sharpless KB, Yang G, Wu P. PMID: 33630577; PMCID: PMC8418205.

View in: PubMed Mentions: 40 Fields:
Che Chemistry
Translation:Humans Animals Cells
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry. J Am Chem Soc. 2020 06 24; 142(25):10899-10904. Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. PMID: 32479075; PMCID: PMC7751259.

View in: PubMed Mentions: 50 Fields:
Che Chemistry
Translation:Humans Cells
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):18808-18814. Zheng Q, Woehl JL, Kitamura S, Santos-Martins D, Smedley CJ, Li G, Forli S, Moses JE, Wolan DW, Sharpless KB. PMID: 31484779; PMCID: PMC6754619.

View in: PubMed Mentions: 73 Fields:
Sci Science
Translation:Humans Cells
The growing applications of SuFEx click chemistry. Chem Soc Rev. 2019; 48:4731-4758. Barrow AS, Smedley CJ, Zheng Q, Li S, Dong J, Moses JE. View Publication.
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angew Chem Int Ed Engl. 2019 03 26; 58(14):4552-4556. Smedley CJ, Zheng Q, Gao B, Li S, Molino A, Duivenvoorden HM, Parker BS, Wilson DJD, Sharpless KB, Moses JE. PMID: 30740848.

View in: PubMed Mentions: 18 Fields:
Che Chemistry
Translation:Cells
Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry. 2018 Jul 20; 24(41):10550-10556. Gahtory D, Sen R, Pujari S, Li S, Zheng Q, Moses JE, Sharpless KB, Zuilhof H. PMID: 29949211; PMCID: PMC6099289.

View in: PubMed Mentions: 17 Fields:
Che Chemistry
Bifluoride-catalysed sulfur(VI) fluoride exchange reaction for the synthesis of polysulfates and polysulfonates. Nat Chem. 2017 11; 9(11):1083-1088. Gao B, Zhang L, Zheng Q, Zhou F, Klivansky LM, Lu J, Liu Y, Dong J, Wu P, Sharpless KB. PMID: 29064495; PMCID: PMC5972039.

View in: PubMed Mentions: 57 Fields:
Che Chemistry
Translation:Cells
SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts. Angew Chem Int Ed Engl. 2017 09 04; 56(37):11203-11208. Wang H, Zhou F, Ren G, Zheng Q, Chen H, Gao B, Klivansky L, Liu Y, Wu B, Xu Q, Lu J, Sharpless KB, Wu P. PMID: 28792119; PMCID: PMC5665377.

View in: PubMed Mentions: 31 Fields:
Che Chemistry
Translation:Cells
Palladium-Catalyzed Fluorosulfonylvinylation of Organic Iodides. Angew Chem Int Ed Engl. 2017 04 18; 56(17):4849-4852. Zha GF, Zheng Q, Leng J, Wu P, Qin HL, Sharpless KB. PMID: 28370917; PMCID: PMC5653204.

View in: PubMed Mentions: 20 Fields:
Che Chemistry
Aryl Fluorosulfate Trapped Staudinger Reduction. Org Lett. 2017 04 07; 19(7):1582-1585. Ren G, Zheng Q, Wang H. PMID: 28332844; PMCID: PMC5922792.

View in: PubMed Mentions: 6 Fields:
Bio Biochemistry
Translation:Cells
Ethenesulfonyl Fluoride (ESF): An On-Water Procedure for the Kilogram-Scale Preparation. J Org Chem. 2016 11 18; 81(22):11360-11362. Zheng Q, Dong J, Sharpless KB. PMID: 27764941.

View in: PubMed Mentions: 19 Fields:
Che Chemistry
A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry. Angew Chem Int Ed Engl. 2016 11 02; 55(45):14155-14158. Qin HL, Zheng Q, Bare GA, Wu P, Sharpless KB. PMID: 27723200; PMCID: PMC5102157.

View in: PubMed Mentions: 38 Fields:
Che Chemistry
Translation:Cells
Mild-condition synthesis of allenes from alkynes and aldehydes mediated by tetrahydroisoquinoline (THIQ). J Org Chem. 2013 Dec 06; 78(23):11783-93. Jiang GJ, Zheng QH, Dou M, Zhuo LG, Meng W, Yu ZX. PMID: 24266693.

View in: PubMed Mentions: 1 Fields:
Che Chemistry