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Rachael Jackman, PhD

Title(s)Associate Professor, Laboratory Medicine
SchoolSchool of Medicine
AddressVitalant Research Institute
270 Masonic Ave
San Francisco CA 94118
Phone415-923-5773
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    The impact of illness and medical treatments on the alloantibody response to platelet transfusion
    NIH/NHLBI R01HL144501Jul 17, 2019 - Jun 30, 2023
    Role: Principal Investigator
    Mechanisms regulating alloimmunization and tolerance with pathogen reduction and transfusion of allogeneic platelets
    NIH/NHLBI R01HL133024Jul 1, 2016 - Apr 30, 2019
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immunodeficient mice are better for modeling the transfusion of human blood components than wild-type mice. PLoS One. 2020; 15(7):e0237106. Blessinger SA, Tran JQ, Jackman RP, Gilfanova R, Rittenhouse J, Gutierrez AG, Heitman JW, Hazegh K, Kanias T, Muench MO. PMID: 32735605.
      View in: PubMed   Mentions:    Fields:    
    2. A small allelic variant in donor class I MHC is sufficient to induce alloantibodies following transfusion of standard or pathogen-reduced platelets in mice. Vox Sang. 2020 Jul; 115(5):367-376. Jackman RP, Heitman JW, Muench MO. PMID: 32201962.
      View in: PubMed   Mentions:    Fields:    
    3. Pathogen reduction with riboflavin and ultraviolet light induces a quasi-apoptotic state in blood leukocytes. Transfusion. 2019 11; 59(11):3501-3510. Tran JQ, Muench MO, Heitman JW, Jackman RP. PMID: 31599981.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    4. Lack of persistent microchimerism in contemporary transfused trauma patients. Transfusion. 2019 11; 59(11):3329-3336. Jackman RP, Utter GH, Lee TH, Montalvo L, Wen L, Chafets D, Rivers RM, Kopko PM, Norris PJ, Busch MP. PMID: 31518003.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Potential of Membranes Surrounding the Fetus as Immunoprotective Cell-Carriers for Allogeneic Transplantations. Transplant Direct. 2019 Jun; 5(6):e460. Togarrati PP, Dinglasan N, Yee E, Heitman JW, Jackman RP, Geisberg M, Norris PJ, Bárcena A, Muench MO. PMID: 31321294.
      View in: PubMed   Mentions:
    6. Allogeneic major histocompatibility complex antigens are necessary and sufficient for partial tolerance induced by transfusion of pathogen reduced platelets in mice. Vox Sang. 2019 Apr; 114(3):207-215. Tran JQ, Muench MO, Heitman JW, Jackman RP. PMID: 30734299.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    7. Increased alloreactive and autoreactive antihuman leucocyte antigen antibodies associated with systemic lupus erythematosus and rheumatoid arthritis. Lupus Sci Med. 2018; 5(1):e000278. Jackman RP, Cruz GI, Nititham J, Triulzi DJ, Barcellos LF, Criswell LA, Norris PJ, Busch MP. PMID: 30305912.
      View in: PubMed   Mentions:
    8. Reduced MHC alloimmunization and partial tolerance protection with pathogen reduction of whole blood. Transfusion. 2017 02; 57(2):337-348. Jackman RP, Muench MO, Inglis H, Heitman JW, Marschner S, Goodrich RP, Norris PJ. PMID: 27859333.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    9. C1q-binding anti-HLA antibodies do not predict platelet transfusion failure in Trial to Reduce Alloimmunization to Platelets study participants. Transfusion. 2016 06; 56(6):1442-50. Jackman RP, Lee JH, Pei R, Bolgiano D, Lebedeva M, Slichter SJ, Norris PJ. PMID: 27079754.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Reduced alloimmunization in mice following repeated transfusion with pathogen-reduced platelets. Transfusion. 2016 06; 56(6):1419-29. Muench MO, Heitman JW, Inglis H, Fomin ME, Marschner S, Goodrich RP, Norris PJ, Jackman RP. PMID: 27028210.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    11. Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro. Blood. 2014 Jan 30; 123(5):687-96. Danesh A, Inglis HC, Jackman RP, Wu S, Deng X, Muench MO, Heitman JW, Norris PJ. PMID: 24335232.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    12. Leukoreduction and ultraviolet treatment reduce both the magnitude and the duration of the HLA antibody response. Transfusion. 2014 Mar; 54(3):672-80. Jackman RP, Deng X, Bolgiano D, Utter GH, Schechterly C, Lebedeva M, Operskalski E, Luban NL, Alter H, Busch MP, Slichter SJ, Norris PJ. PMID: 23808544.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    13. Immunomodulation in transfused trauma patients. Curr Opin Anaesthesiol. 2013 Apr; 26(2):196-203. Jackman RP. PMID: 23303513.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    14. Immune modulation and lack of alloimmunization following transfusion with pathogen-reduced platelets in mice. Transfusion. 2013 Nov; 53(11):2697-709. Jackman RP, Muench MO, Heitman JW, Inglis HC, Law JP, Marschner S, Goodrich RP, Norris PJ. PMID: 23451715.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    15. Low-level HLA antibodies do not predict platelet transfusion failure in TRAP study participants. Blood. 2013 Apr 18; 121(16):3261-6; quiz 3299. Jackman RP, Deng X, Bolgiano D, Lebedeva M, Heitman JW, Busch MP, Slichter SJ, Norris PJ. PMID: 23393051.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Transfusion-associated microchimerism: the hybrid within. Transfus Med Rev. 2013 Jan; 27(1):10-20. Bloch EM, Jackman RP, Lee TH, Busch MP. PMID: 23102759.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    17. Distinct roles of trauma and transfusion in induction of immune modulation after injury. Transfusion. 2012 Dec; 52(12):2533-50. Jackman RP, Utter GH, Muench MO, Heitman JW, Munz MM, Jackman RW, Biswas HH, Rivers RM, Tobler LH, Busch MP, Norris PJ. PMID: 22452342.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    18. Effects of blood sample age at time of separation on measured cytokine concentrations in human plasma. Clin Vaccine Immunol. 2011 Feb; 18(2):318-26. Jackman RP, Utter GH, Heitman JW, Hirschkorn DF, Law JP, Gefter N, Busch MP, Norris PJ. PMID: 21159926.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. Understanding loss of donor white blood cell immunogenicity after pathogen reduction: mechanisms of action in ultraviolet illumination and riboflavin treatment. Transfusion. 2009 Dec; 49(12):2686-99. Jackman RP, Heitman JW, Marschner S, Goodrich RP, Norris PJ. PMID: 19682337.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    20. CTLA-4 differentially regulates the immunological synapse in CD4 T cell subsets. J Immunol. 2007 May 01; 178(9):5543-51. Jackman RP, Balamuth F, Bottomly K. PMID: 17442936.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    21. Mycobacterium tuberculosis/HIV-1 coinfection and disease: role of human leukocyte antigen variation. J Infect Dis. 2004 Mar 15; 189(6):1084-90. Louie LG, Hartogensis WE, Jackman RP, Schultz KA, Zijenah LS, Yiu CH, Nguyen VD, Sohsman MY, Katzenstein DK, Mason PR. PMID: 14999612.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
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