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Lindsey Criswell, MD, MPH

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address513 Parnassus Avenue
San Francisco CA 94117
Phone415-476-9026
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPost-Doc Fellow/Scholar1992 Medicine
    University of California, San Francisco Residency Medicine
    University of California, San FranciscoM.D.1986 Medicine
    Collapse Awards and Honors
    UCSF2012Jean S. Engleman Distinguished Professor of Rheumatology
    UCSF2008  - 2011Kenneth H. Fye, M.D., Endowed Chair in Rheumatology
    Mary Kirkland Center for Lupus Research2006  - 2008Kirkland Scholar Award
    American College of Rheumatology2003Henry Kunkel Young Investigator Award

    Collapse Overview 
    Collapse Overview
    The focus of my research program is the genetics and epidemiology of human autoimmune disease, particularly rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). My research unit has devoted substantial effort to the performance of genome wide association (GWA) and other genetics studies, which have led to the identification of over 30 genes that contribute to risk and outcome of these disorders. This work has also highlighted key biologic pathways responsible for disease onset and progression, which can inform more basic research to define the mechanism of these genetic associations. Given the heterogeneity of these disorders, we are also devoting substantial effort to the refinement of genotype-phenotype associations, such as the specificity of genetic associations for serologic or clinical subphenotypes. Several genes we have been studying, including STAT4 and TNFAIP3, are also of interest due to emerging evidence supporting their association with multiple autoimmune disorders and phenotypes. Given the strong association of the major histocompatibility complex (MHC) region with multiple autoimmune disorders, we are performing fine mapping studies of this region in order to further define the complex genetic associations of this region with SLE, RA and related phenotypes. We are also pursuing studies designed to better understand ethnic differences in autoimmune disease risk and outcome. Lastly, we have initiated several recent studies that seek to define the contribution of epigenetic factors, particularly DNA methylation patterns, to autoimmune disease risk and outcome.


    Collapse Research 
    Collapse Research Activities and Funding
    Resource-based Center for the Advancement of Precision Medicine in Rheumatology
    NIH/NIAMS P30AR070155Sep 21, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Genetic and epigenetic contributions to Sjogren's syndrome
    NIH/NIDCR R03DE024316Jan 1, 2015 - Dec 31, 2016
    Role: Principal Investigator
    Genomics of Lupus
    NIH P01AI083194Aug 15, 2009 - Jul 31, 2014
    Role: Co-Investigator
    Dissecting the HLA contribution to Rheumatoid Arthritis
    NIH/NIAID R01AI065841Mar 1, 2006 - Feb 29, 2012
    Role: Principal Investigator
    NIAMS Multidisciplinary Clinical Research Center
    NIH P60AR053308Jan 1, 2006 - Apr 30, 2017
    Role: Co-Investigator
    Novel strategies for defining the role of HLA in SLE
    NIH/NIAMS R01AR052300Apr 10, 2005 - Mar 31, 2011
    Role: Principal Investigator
    The Genetic Epidemiology of RA and SLE
    NIH/NIAMS K24AR002175Sep 27, 2001 - May 31, 2007
    Role: Principal Investigator
    TESTING SLE CANDIDATE LOCI USING CASES AND THEIR PARENTS
    NIH/NIAMS R01AR044804Jan 15, 1999 - Dec 31, 2003
    Role: Principal Investigator
    PEDIATRIC CLINICAL RESEARCH CENTER
    NIH/NCRR M01RR001271Dec 1, 1981 - Mar 31, 2007
    Role: Co-Investigator
    MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR
    NIH/NIAMS P60AR020684Sep 15, 1977 - Dec 31, 2003
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Gourh P, Remmers EF, Boyden SE, Alexander T, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA, Steen VD, Ramos PS, Silver RM, Korman B, Varga J, Schiopu E, Khanna D, Hsu V, Gordon JK, Saketkoo LA, Gladue H, Kron B, Criswell L, Derk CT, Bridges SL, Shanmugam VK, Kolstad KD, Chung L, Jan R, Bernstein EJ, Goldberg A, Trojanowski M, Kafaja S, Maksimowicz-McKinnon KM, Mullikin JC, Adeyemo A, Rotimi C, Boin F, Kastner DL, Wigley FM. Whole-Exome Sequencing to Identify Rare Variants and Gene Networks that Increase Susceptibility to Scleroderma in African Americans. Arthritis Rheumatol. 2018 May 06. PMID: 29732714.
      View in: PubMed
    2. Gonzales JA, Chou A, Rose-Nussbaumer JR, Bunya VY, Criswell L, Shiboski CH, Lietman TM. How Are Ocular Signs and Symptoms of Dry Eye Associated with Depression in Women with and without Sjögren's Syndrome? Am J Ophthalmol. 2018 Apr 12. PMID: 29655640.
      View in: PubMed
    3. Mariette X, Criswell L. Primary Sjögren's Syndrome. N Engl J Med. 2018 03 08; 378(10):931-939. PMID: 29514034.
      View in: PubMed
    4. Leonard D, Svenungsson E, Dahlqvist J, Alexsson A, Ärlestig L, Taylor KE, Sandling JK, Bengtsson C, Frodlund M, Jönsen A, Eketjäll S, Jensen-Urstad K, Gunnarsson I, Sjöwall C, Bengtsson AA, Eloranta ML, Syvänen AC, Rantapää-Dahlqvist S, Criswell L, Rönnblom L. Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis. Ann Rheum Dis. 2018 Mar 07. PMID: 29514802.
      View in: PubMed
    5. Mok A, Rhead B, Holingue C, Shao X, Quach HL, Quach D, Sinclair E, Graf J, Imboden J, Link T, Harrison R, Chernitskiy V, Barcellos LF, Criswell L. Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. Arthritis Rheumatol. 2018 Apr; 70(4):528-536. PMID: 29287311.
      View in: PubMed
    6. Shiboski CH, Baer AN, Shiboski SC, Lam M, Challacombe S, Lanfranchi HE, Schiødt M, Shirlaw P, Srinivasan M, Umehara H, Vivino FB, Akpek E, Bunya V, Vollenweider CF, Greenspan JS, Daniels TE, Criswell L. Natural History and Predictors of Progression to Sjögren's Syndrome Among Participants of the Sjögren's International Collaborative Clinical Alliance Registry. Arthritis Care Res (Hoboken). 2018 Feb; 70(2):284-294. PMID: 28437595.
      View in: PubMed
    7. Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell L, Ye CJ. Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. Nat Biotechnol. 2018 Jan; 36(1):89-94. PMID: 29227470.
      View in: PubMed
    8. Morgan ND, Shah AA, Mayes MD, Domsic RT, Medsger TA, Steen VD, Varga J, Carns M, Ramos PS, Silver RM, Schiopu E, Khanna D, Hsu V, Gordon JK, Gladue H, Saketkoo LA, Criswell L, Derk CT, Trojanowski MA, Shanmugam VK, Chung L, Valenzuela A, Jan R, Goldberg A, Remmers EF, Kastner DL, Wigley FM, Gourh P, Boin F. Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database. Medicine (Baltimore). 2017 Dec; 96(51):e8980. PMID: 29390428.
      View in: PubMed
    9. Seielstad M, Page GP, Gaddis N, Lanteri M, Lee TH, Kakaiya R, Barcellos LF, Criswell L, Triulzi D, Norris PJ, Busch MP. Genomewide association study of HLA alloimmunization in previously pregnant blood donors. Transfusion. 2018 Feb; 58(2):402-412. PMID: 29168253.
      View in: PubMed
    10. Chou A, Gonzales JA, Daniels TE, Criswell L, Shiboski SC, Shiboski CH. Health-related quality of life and depression among participants in the Sjögren's International Collaborative Clinical Alliance registry. RMD Open. 2017; 3(2):e000495. PMID: 29018565.
      View in: PubMed
    11. Fogel O, Rivière E, Seror R, Nocturne G, Boudaoud S, Ly B, Gottenberg JE, Le Guern V, Dubost JJ, Nititham J, Taylor KE, Chanson P, Dieudé P, Criswell L, Jagla B, Thai A, Mingueneau M, Mariette X, Miceli-Richard C. Role of the IL-12/IL-35 balance in patients with Sjögren syndrome. J Allergy Clin Immunol. 2017 Sep 12. PMID: 28916184.
      View in: PubMed
    12. Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell L, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ. Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021. PMID: 28714469.
      View in: PubMed
    13. Taylor KE, Wong Q, Levine DM, McHugh C, Laurie C, Doheny K, Lam MY, Baer AN, Challacombe S, Lanfranchi H, Schiødt M, Srinivasan M, Umehara H, Vivino FB, Zhao Y, Shiboski SC, Daniels TE, Greenspan JS, Shiboski CH, Criswell L. Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry. Arthritis Rheumatol. 2017 06; 69(6):1294-1305. PMID: 28076899.
      View in: PubMed
    14. Vitali C, Scofield H, Shiboski SC, Criswell L, Lietman TM, Seror R, Labetoulle M, Mariette X, Rasmussen A, Bowman SJ, Shiboski CH. Reply. Arthritis Rheumatol. 2017 Jun; 69(6):1342. PMID: 28257605.
      View in: PubMed
    15. Cruz GI, Shao X, Quach H, Ho KA, Sterba K, Noble JA, Patsopoulos NA, Busch MP, Triulzi DJ, Wong WS, Solomon BD, Niederhuber JE, Criswell L, Barcellos LF. Increased risk of rheumatoid arthritis among mothers with children who carry DRB1 risk-associated alleles. Ann Rheum Dis. 2017 Aug; 76(8):1405-1410. PMID: 28391248.
      View in: PubMed
    16. Hall SC, Hassis ME, Williams KE, Albertolle ME, Prakobphol A, Dykstra AB, Laurance M, Ona K, Niles RK, Prasad N, Gormley M, Shiboski C, Criswell L, Witkowska HE, Fisher SJ. Alterations in the Salivary Proteome and N-Glycome of Sjögren's Syndrome Patients. J Proteome Res. 2017 04 07; 16(4):1693-1705. PMID: 28282148.
      View in: PubMed
    17. Rhead B, Holingue C, Cole M, Shao X, Quach HL, Quach D, Shah K, Sinclair E, Graf J, Link T, Harrison R, Rahmani E, Halperin E, Wang W, Firestein GS, Barcellos LF, Criswell L. Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes. Arthritis Rheumatol. 2017 03; 69(3):550-559. PMID: 27723282.
      View in: PubMed
    18. Mok A, Solomon O, Nayak RR, Coit P, Quach HL, Nititham J, Sawalha AH, Barcellos LF, Criswell L, Chung SA. Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses. Lupus Sci Med. 2016; 3(1):e000183. PMID: 28074145.
      View in: PubMed
    19. Cole MB, Quach H, Quach D, Baker A, Taylor KE, Barcellos LF, Criswell L. Epigenetic Signatures of Salivary Gland Inflammation in Sjögren's Syndrome. Arthritis Rheumatol. 2016 12; 68(12):2936-2944. PMID: 27332624.
      View in: PubMed
    20. Shiboski CH, Shiboski SC, Seror R, Criswell L, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Mariette X. 2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts. Arthritis Rheumatol. 2017 01; 69(1):35-45. PMID: 27785888.
      View in: PubMed
    21. Shiboski CH, Shiboski SC, Seror R, Criswell L, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Mariette X. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: A consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis. 2017 Jan; 76(1):9-16. PMID: 27789466.
      View in: PubMed
    22. Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VS, Dillenberger D, Neto EC, Norman T, Aittokallio T, Ammad-Ud-Din M, Azencott CA, Bellón V, Boeva V, Bunte K, Chheda H, Cheng L, Corander J, Dumontier M, Goldenberg A, Gopalacharyulu P, Hajiloo M, Hidru D, Jaiswal A, Kaski S, Khalfaoui B, Khan SA, Kramer ER, Marttinen P, Mezlini AM, Molparia B, Pirinen M, Saarela J, Samwald M, Stoven V, Tang H, Tang J, Torkamani A, Vert JP, Wang B, Wang T, Wennerberg K, Wineinger NE, Xiao G, Xie Y, Yeung R, Zhan X, Zhao C. Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nat Commun. 2016 Oct 10; 7:13205. PMID: 27721464.
      View in: PubMed
    23. Bunya VY, Bhosai SJ, Heidenreich AM, Kitagawa K, Larkin GB, Lietman TM, Gaynor BD, Akpek EK, Massaro-Giordano M, Srinivasan M, Porco TC, Whitcher JP, Shiboski SC, Criswell L, Shiboski CH. Association of Dry Eye Tests With Extraocular Signs Among 3514 Participants in the Sjögren's Syndrome International Registry. Am J Ophthalmol. 2016 Dec; 172:87-93. PMID: 27644591.
      View in: PubMed
    24. Mak AC, Tang PL, Cleveland C, Smith MH, Kari Connolly M, Katsumoto TR, Wolters PJ, Kwok PY, Criswell L. Brief Report: Whole-Exome Sequencing for Identification of Potential Causal Variants for Diffuse Cutaneous Systemic Sclerosis. Arthritis Rheumatol. 2016 09; 68(9):2257-62. PMID: 27111861.
      View in: PubMed
    25. Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VS, Dillenberger D, Neto EC, Norman T, Aittokallio T, Ammad-Ud-Din M, Azencott CA, Bellón V, Boeva V, Bunte K, Chheda H, Cheng L, Corander J, Dumontier M, Goldenberg A, Gopalacharyulu P, Hajiloo M, Hidru D, Jaiswal A, Kaski S, Khalfaoui B, Khan SA, Kramer ER, Marttinen P, Mezlini AM, Molparia B, Pirinen M, Saarela J, Samwald M, Stoven V, Tang H, Tang J, Torkamani A, Vert JP, Wang B, Wang T, Wennerberg K, Wineinger NE, Xiao G, Xie Y, Yeung R, Zhan X, Zhao C. Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nat Commun. 2016 Aug 23; 7:12460. PMID: 27549343; PMCID: PMC4996969.
    26. Cruz GI, Shao X, Quach H, Ho KA, Sterba K, Noble JA, Patsopoulos NA, Busch MP, Triulzi DJ, Wong WS, Solomon BD, Niederhuber JE, Criswell L, Barcellos LF. A Child's HLA-DRB1 genotype increases maternal risk of systemic lupus erythematosus. J Autoimmun. 2016 Nov; 74:201-207. PMID: 27388144.
      View in: PubMed
    27. Lessard CJ, Sajuthi S, Zhao J, Kim K, Ice JA, Li H, Ainsworth H, Rasmussen A, Kelly JA, Marion M, Bang SY, Joo YB, Choi J, Lee HS, Kang YM, Suh CH, Chung WT, Lee SK, Choe JY, Shim SC, Oh JH, Kim YJ, Han BG, Shen N, Howe HS, Wakeland EK, Li QZ, Song YW, Gaffney PM, Alarcón-Riquelme ME, Criswell L, Jacob CO, Kimberly RP, Vyse TJ, Harley JB, Sivils KL, Bae SC, Langefeld CD, Tsao BP. Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans. Arthritis Rheumatol. 2016 05; 68(5):1197-1209. PMID: 26663301; PMCID: PMC4981330.
    28. Alarcón-Riquelme ME, Ziegler JT, Molineros J, Howard TD, Moreno-Estrada A, Sánchez-Rodríguez E, Ainsworth HC, Ortiz-Tello P, Comeau ME, Rasmussen A, Kelly JA, Adler A, Acevedo-Vázquez EM, Cucho-Venegas JM, García-De la Torre I, Cardiel MH, Miranda P, Catoggio LJ, Maradiaga-Ceceña M, Gaffney PM, Vyse TJ, Criswell L, Tsao BP, Sivils KL, Bae SC, James JA, Kimberly RP, Kaufman KM, Harley JB, Esquivel-Valerio JA, Moctezuma JF, García MA, Berbotto GA, Babini AM, Scherbarth H, Toloza S, Baca V, Nath SK, Aguilar Salinas C, Orozco L, Tusié-Luna T, Zidovetzki R, Pons-Estel BA, Langefeld CD, Jacob CO. Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43. PMID: 26606652; PMCID: PMC4829354 [Available on 10/01/16].
    29. Deng Y, Zhao J, Sakurai D, Sestak AL, Osadchiy V, Langefeld CD, Kaufman KM, Kelly JA, James JA, Petri MA, Bae SC, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Criswell L, Freedman BI, Kamen DL, Gilkeson GS, Jacob CO, Merrill JT, Gaffney PM, Sivils KM, Niewold TB, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Boackle SA, Vilá LM, Sohn II, Lee S, Chang DM, Song YW, Vyse TJ, Harley JB, Brown EE, Edberg JC, Kimberly RP, Cantor RM, Hahn BH, Grossman JM, Tsao BP. Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis. 2016 Nov; 75(11):2007-2013. PMID: 26783109.
      View in: PubMed
    30. Elboudwarej E, Cole M, Briggs FB, Fouts A, Fain PR, Quach H, Quach D, Sinclair E, Criswell L, Lane JA, Steck AK, Barcellos LF, Noble JA. Hypomethylation within gene promoter regions and type 1 diabetes in discordant monozygotic twins. J Autoimmun. 2016 Apr; 68:23-9. PMID: 26782299; PMCID: PMC4792657 [Available on 04/01/17].
    31. Zhao J, Wu H, Langefeld CD, Kaufman KM, Kelly JA, Bae SC. Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus. Clin Immunol. 2015 Dec; 161(2):157-62. PMID: 26385092; PMCID: PMC4658308 [Available on 12/01/16].
    32. Nocturne G, Tarn J, Boudaoud S, Locke J, Miceli-Richard C, Hachulla E, Dubost JJ, Bowman S, Gottenberg JE, Criswell L, Lessard CJ, Sivils KL, Carapito R, Bahram S, Seror R, Ng WF, Mariette X. Germline variation of TNFAIP3 in primary Sjögren's syndrome-associated lymphoma. Ann Rheum Dis. 2016 Apr; 75(4):780-3. PMID: 26338037.
      View in: PubMed
    33. Hall JC, Baer AN, Shah AA, Criswell L, Shiboski CH, Rosen A, Casciola-Rosen L. Molecular Subsetting of Interferon Pathways in Sjögren's Syndrome. Arthritis Rheumatol. 2015 Sep; 67(9):2437-46. PMID: 25988820.
      View in: PubMed
    34. Nocturne G, Pavy S, Boudaoud S, Seror R, Goupille P, Chanson P, van der Heijde D, van Gaalen F, Berenbaum F, Mariette X, Briot K, Feydy A, Claudepierre P, Dieudé P, Nithitham J, Taylor KE, Criswell L, Dougados M, Roux C, Miceli-Richard C. Increase in Dickkopf-1 Serum Level in Recent Spondyloarthritis. Data from the DESIR Cohort. PLoS One. 2015; 10(8):e0134974. PMID: 26313358; PMCID: PMC4552086.
    35. Chung SA, Nititham J, Elboudwarej E, Quach HL, Taylor KE, Barcellos LF, Criswell L. Genome-Wide Assessment of Differential DNA Methylation Associated with Autoantibody Production in Systemic Lupus Erythematosus. PLoS One. 2015; 10(7):e0129813. PMID: 26192630; PMCID: PMC4508022.
    36. Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell L, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9. PMID: 25865496.
      View in: PubMed
    37. Miceli-Richard C, Taylor KE, Nititham J, Seror R, Nocturne G, Boudaoud S, Dieude P, Constantin A, Devauchelle-Pensec V, Tobón GJ, Mariette X, Criswell L. Genetic contribution of DKK-1 polymorphisms to RA structural severity and DKK-1 level of expression. Ann Rheum Dis. 2015 Jul; 74(7):1480-1. PMID: 25805736.
      View in: PubMed
    38. Baer AN, McAdams DeMarco M, Shiboski SC, Lam MY, Challacombe S, Daniels TE, Dong Y, Greenspan JS, Kirkham BW, Lanfranchi HE, Schiødt M, Srinivasan M, Umehara H, Vivino FB, Vollenweider CF, Zhao Y, Criswell L, Shiboski CH. The SSB-positive/SSA-negative antibody profile is not associated with key phenotypic features of Sjögren's syndrome. Ann Rheum Dis. 2015 Aug; 74(8):1557-61. PMID: 25735642.
      View in: PubMed
    39. Korman BD, Criswell L. Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance. Curr Rheumatol Rep. 2015 Mar; 17(3):21. PMID: 25777745; PMCID: PMC4361757.
    40. Yelin E, Yazdany J, Tonner C, Trupin L, Criswell L, Katz P, Schmajuk G. Interactions between patients, providers, and health systems and technical quality of care. Arthritis Care Res (Hoboken). 2015 Mar; 67(3):417-24. PMID: 25132660; PMCID: PMC4320034.
    41. Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath S, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Moser KL, Criswell L, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Binjoo Y, Choi J, Bae SC, Boackle SA, Vyse TJ, Guthridge JM, Namjou B, Gaffney PM, Langefeld CD, Kaufman KM, Kelly JA, Harley IT, Harley JB, Kottyan LC. Lupus risk variants in the PXK locus alter B-cell receptor internalization. Front Genet. 2014; 5:450. PMID: 25620976; PMCID: PMC4288052.
    42. Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X, Bowman S. The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet. 2015 Jan 15; 24(2):582-96. PMID: 25205108; PMCID: PMC4275071.
    43. Zhao J, Giles BM, Taylor RL, Yette GA, Lough KM, Ng HL, Abraham LJ, Wu H, Kelly JA, Glenn SB, Adler AJ, Williams AH, Comeau ME, Ziegler JT, Marion M, Alarcón-Riquelme ME. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan; 75(1):242-52. PMID: 25180293; PMCID: PMC4717392.
    44. Kaiser R, Tang LF, Taylor KE, Sterba K, Nititham J, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri M, Rauch J, Miller E, Mesznik K, Kwok PY, Kimberly RP, Salmon JE, Criswell L. A polymorphism in TLR2 is associated with arterial thrombosis in a multiethnic population of patients with systemic lupus erythematosus. Arthritis Rheumatol. 2014 Jul; 66(7):1882-7. PMID: 24578102; PMCID: PMC4269184.
    45. Chung SA, Brown EE, Williams AH, Ramos PS, Berthier CC, Bhangale T, Alarcon-Riquelme ME, Behrens TW, Criswell L, Graham DC, Demirci FY, Edberg JC, Gaffney PM, Harley JB, Jacob CO, Kamboh MI, Kelly JA, Manzi S, Moser-Sivils KL, Russell LP, Petri M, Tsao BP, Vyse TJ, Zidovetzki R, Kretzler M, Kimberly RP, Freedman BI, Graham RR, Langefeld CD. Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. J Am Soc Nephrol. 2014 Dec; 25(12):2859-70. PMID: 24925725; PMCID: PMC4243339.
    46. Guthridge JM, Lu R, Sun H, Sun C, Wiley GB, Dominguez N, Macwana SR, Lessard CJ, Kim-Howard X, Cobb BL, Kaufman KM, Kelly JA, Langefeld CD, Adler AJ, Harley IT, Merrill JT, Gilkeson GS, Kamen DL, Niewold TB, Brown EE, Edberg JC, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, Kimberly RP, Freedman BI, Stevens AM, Boackle SA, Criswell L, Vyse TJ, Behrens TW, Jacob CO, Alarcón-Riquelme ME, Sivils KL, Choi J, Joo YB, Bang SY, Lee HS, Bae SC, Shen N, Qian X, Tsao BP, Scofield RH, Harley JB, Webb CF, Wakeland EK, James JA, Nath SK, Graham RR, Gaffney PM. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet. 2014 Apr 03; 94(4):586-98. PMID: 24702955.
      View in: PubMed
    47. Miceli-Richard C, Criswell L. Genetic, genomic and epigenetic studies as tools for elucidating disease pathogenesis in primary Sjögren's syndrome. Expert Rev Clin Immunol. 2014 Apr; 10(4):437-44. PMID: 24646085.
      View in: PubMed
    48. Freedman BI, Langefeld CD, Andringa KK, Croker JA, Williams AH, Garner NE, Birmingham DJ, Hebert LA, Hicks PJ, Segal MS, Edberg JC, Brown EE, Alarcón GS, Costenbader KH, Comeau ME, Criswell L, Harley JB, James JA, Kamen DL, Lim SS, Merrill JT, Sivils KL, Niewold TB, Patel NM, Petri M, Ramsey-Goldman R, Reveille JD, Salmon JE, Tsao BP, Gibson KL, Byers JR, Vinnikova AK, Lea JP, Julian BA, Kimberly RP. End-stage renal disease in African Americans with lupus nephritis is associated with APOL1. Arthritis Rheumatol. 2014 Feb; 66(2):390-6. PMID: 24504811; PMCID: PMC4002759.
    49. Gong YZ, Nititham J, Taylor K, Miceli-Richard C, Sordet C, Wachsmann D, Bahram S, Georgel P, Criswell L, Sibilia J, Mariette X, Alsaleh G, Gottenberg JE. Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome. J Autoimmun. 2014 Jun; 51:57-66. PMID: 24411167.
      View in: PubMed
    50. Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, Jiang L, Yin J, Ye L, Su DF, Yang J, Xie G, Keystone E, Westra HJ, Esko T, Metspalu A, Zhou X, Gupta N, Mirel D, Stahl EA, Diogo D, Cui J, Liao K, Guo MH, Myouzen K, Kawaguchi T, Coenen MJ, van Riel PL, van de Laar MA, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Bridges SL, Zhernakova A, Toes RE, Tak PP, Miceli-Richard C, Bang SY, Lee HS, Martin J, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Rantapää-Dahlqvist S, Arlestig L, Choi HK, Kamatani Y, Galan P, Lathrop M. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 2014 Feb 20; 506(7488):376-81. PMID: 24390342; PMCID: PMC3944098.
    51. Nocturne G, Boudaoud S, Miceli-Richard C, Viengchareun S, Lazure T, Nititham J, Taylor KE, Ma A, Busato F, Melki J, Lessard CJ, Sivils KL, Dubost JJ, Hachulla E, Gottenberg JE, Lombès M, Tost J, Criswell L, Mariette X. Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome. Blood. 2013 Dec 12; 122(25):4068-76. PMID: 24159176; PMCID: PMC3862283.
    52. Sakurai D, Zhao J, Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarc?n-Riquelme ME. Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013; 9(10):e1003870. PMID: 24130510; PMCID: PMC3794920.
    53. Lu M, Bernatsky S, Ramsey-Goldman R, Petri M, Manzi S, Urowitz MB, Gladman D, Fortin PR, Ginzler EM, Yelin E, Bae SC, Wallace DJ, Jacobsen S, Dooley MA, Peschken CA, Alarcón GS, Nived O, Gottesman L, Criswell L, Sturfelt G, Dreyer L, Lee JL, Clarke AE. Non-lymphoma hematological malignancies in systemic lupus erythematosus. Oncology. 2013; 85(4):235-40. PMID: 24107608; PMCID: PMC3880772.
    54. Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell L, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW. ABIN1 dysfunction as a genetic basis for lupus nephritis. J Am Soc Nephrol. 2013 Nov; 24(11):1743-54. PMID: 23970121.
      View in: PubMed
    55. Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarcón GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel B. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404. PMID: 23950893; PMCID: PMC3737240.
    56. Rusakiewicz S, Nocturne G, Lazure T, Semeraro M, Flament C, Caillat-Zucman S, Sène D, Delahaye N, Vivier E, Chaba K, Poirier-Colame V, Nordmark G, Eloranta ML, Eriksson P, Theander E, Forsblad-d'Elia H, Omdal R, Wahren-Herlenius M, Jonsson R, Rönnblom L, Nititham J, Taylor KE, Lessard CJ, Sivils KL, Gottenberg JE, Criswell L, Miceli-Richard C, Zitvogel L, Mariette X. NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome. Sci Transl Med. 2013 Jul 24; 5(195):195ra96. PMID: 23884468; PMCID: PMC4237161.
    57. Manku H, Langefeld CD, Guerra SG, Malik TH, Alarcon-Riquelme M, Anaya JM, Bae SC, Boackle SA, Brown EE, Criswell L, Freedman BI, Gaffney PM, Gregersen PA, Guthridge JM, Han SH, Harley JB, Jacob CO, James JA, Kamen DL, Kaufman KM, Kelly JA, Martin J, Merrill JT, Moser KL, Niewold TB, Park SY, Pons-Estel BA, Sawalha AH, Scofield RH, Shen N, Stevens AM, Sun C, Gilkeson GS, Edberg JC, Kimberly RP, Nath SK, Tsao BP, Vyse TJ. Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4. PLoS Genet. 2013; 9(7):e1003554. PMID: 23874208; PMCID: PMC3715547.
    58. Ramos PS, Oates JC, Kamen DL, Williams AH, Gaffney PM, Kelly JA, Kaufman KM, Kimberly RP, Niewold TB, Jacob CO, Tsao BP, Alarcón GS, Brown EE, Edberg JC, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, James JA, Guthridge JM, Merrill JT, Boackle SA, Freedman BI, Scofield RH, Stevens AM, Vyse TJ, Criswell L, Moser KL, Alarcón-Riquelme ME, Langefeld CD, Harley JB, Gilkeson GS. Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9. PMID: 23637325; PMCID: PMC3735344.
    59. Miller ZA, Rankin KP, Graff-Radford NR, Takada LT, Sturm VE, Cleveland CM, Criswell L, Jaeger PA, Stan T, Heggeli KA, Hsu SC, Karydas A, Khan BK, Grinberg LT, Gorno-Tempini ML, Boxer AL, Rosen HJ, Kramer JH, Coppola G, Geschwind DH, Rademakers R, Seeley WW, Wyss-Coray T, Miller BL. TDP-43 frontotemporal lobar degeneration and autoimmune disease. J Neurol Neurosurg Psychiatry. 2013 Sep; 84(9):956-62. PMID: 23543794.
      View in: PubMed
    60. Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL, Herenius M, Doorenspleet ME, Tak PP, Crusius JB, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PL, van de Laar M, Guchelaar HJ, Shadick NA, Allaart CF, Huizinga TW, Toes RE, Kimberly RP, Bridges SL, Criswell L, Moreland LW, Fonseca JE, de Vries N, Stranger BE, De Jager PL, Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Padyukov L, Coenen MJ, Karlson EW, Plenge RM. Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis. PLoS Genet. 2013 Mar; 9(3):e1003394. PMID: 23555300; PMCID: PMC3610685.
    61. Deng Y, Zhao J, Sakurai D, Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH, Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Vyse TJ, Pons-Estel BA. MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. PLoS Genet. 2013; 9(2):e1003336. PMID: 23468661; PMCID: PMC3585142.
    62. Molineros JE, Maiti AK, Sun C, Looger LL, Han S, Kim-Howard X, Glenn S, Adler A, Kelly JA, Niewold TB, Gilkeson GS, Brown EE, Alarcón GS, Edberg JC, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, Freedman BI, Tsao BP, Criswell L, Jacob CO, Moore JH, Vyse TJ, Langefeld CL, Guthridge JM, Gaffney PM, Moser KL, Scofield RH, Alarcón-Riquelme ME. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222. PMID: 23441136; PMCID: PMC3575474.
    63. Bernatsky S, Ramsey-Goldman R, Labrecque J, Joseph L, Boivin JF, Petri M, Zoma A, Manzi S, Urowitz MB, Gladman D, Fortin PR, Ginzler E, Yelin E, Bae SC, Wallace DJ, Edworthy S, Jacobsen S, Gordon C, Dooley MA, Peschken CA, Hanly JG, Alarcón GS, Nived O, Ruiz-Irastorza G, Isenberg D, Rahman A, Witte T, Aranow C, Kamen DL, Steinsson K, Askanase A, Barr S, Criswell L, Sturfelt G, Patel NM, Senécal JL, Zummer M, Pope JE, Ensworth S, El-Gabalawy H, McCarthy T, Dreyer L, Sibley J, St Pierre Y, Clarke AE. Cancer risk in systemic lupus: an updated international multi-centre cohort study. J Autoimmun. 2013 May; 42:130-5. PMID: 23410586; PMCID: PMC3646904.
    64. Bernatsky S, Ramsey-Goldman R, Joseph L, Boivin JF, Costenbader KH, Urowitz MB, Gladman DD, Fortin PR, Nived O, Petri MA, Jacobsen S, Manzi S, Ginzler EM, Isenberg D, Rahman A, Gordon C, Ruiz-Irastorza G, Yelin E, Bae SC, Wallace DJ, Peschken CA, Dooley MA, Edworthy SM, Aranow C, Kamen DL, Romero-Diaz J, Askanase A, Witte T, Barr SG, Criswell L, Sturfelt GK, Blanco I, Feldman CH, Dreyer L, Patel NM, St Pierre Y, Clarke AE. Lymphoma risk in systemic lupus: effects of disease activity versus treatment. Ann Rheum Dis. 2014 Jan; 73(1):138-42. PMID: 23303389; PMCID: PMC3855611.
    65. Katz PP, Yazdany J, Trupin L, Schmajuk G, Margaretten M, Barton J, Criswell L, Yelin EH. Sex differences in assessment of obesity in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2013 Jan; 65(1):62-70. PMID: 22833513; PMCID: PMC3501549.
    66. Kaiser R, Taylor KE, Deng Y, Zhao J, Li Y, Nititham J, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vila LM, Petri M, Kimberly RP, Feng X, Sun L, Shen N, Li W, Lu JX, Wakeland EK, Li QZ, Yang W, Lau YL, Liu FL, Chang DM, Yu CY, Song YW, Tsao BP, Criswell L. Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians. Arthritis Rheum. 2013 Jan; 65(1):211-5. PMID: 23124848; PMCID: PMC3670944.
    67. Wang C, Ahlford A, Järvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Sjöwall C, Julkunen H, Criswell L, Graham RR, Behrens TW, Kere J, Rönnblom L, Syvänen AC, Sandling JK. Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations. Eur J Hum Genet. 2013 Sep; 21(9):994-9. PMID: 23249952; PMCID: PMC3746253.
    68. Umicevic Mirkov M, Cui J, Vermeulen SH, Stahl EA, Toonen EJ, Makkinje RR, Lee AT, Huizinga TW, Allaart R, Barton A, Mariette X, Miceli CR, Criswell L, Tak PP, de Vries N, Saevarsdottir S, Padyukov L, Bridges SL, van Schaardenburg DJ, Jansen TL, Dutmer EA, van de Laar MA, Barrera P, Radstake TR, van Riel PL, Scheffer H, Franke B, Brunner HG, Plenge RM, Gregersen PK, Guchelaar HJ, Coenen MJ. Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis. Ann Rheum Dis. 2013 Aug; 72(8):1375-81. PMID: 23233654; PMCID: PMC4169706.
    69. Adrianto I, Wang S, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME. Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum. 2012 Nov; 64(11):3695-705. PMID: 22833143; PMCID: PMC3485412.
    70. Sánchez E, Rasmussen A, Riba L, Acevedo-Vasquez E, Kelly JA, Langefeld CD, Williams AH, Ziegler JT, Comeau ME, Marion MC, García-De La Torre I, Maradiaga-Ceceña MA, Cardiel MH, Esquivel-Valerio JA, Rodriguez-Amado J, Moctezuma JF, Miranda P, Perandones CE, Castel C, Laborde HA, Alba P, Musuruana JL, Goecke IA, Anaya JM, Kaufman KM, Adler A, Glenn SB, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Vilá LM, Criswell L, Gilkeson GS, Niewold TB, Martín J, Vyse TJ, Boackle SA, Ramsey-Goldman R, Scofield RH, Petri M, Merrill JT, Reveille JD, Tsao BP, Orozco L, Baca V, Moser KL, Gaffney PM, James JA, Harley JB, Tusié-Luna T, Pons-Estel BA, Jacob CO, Alarcón-Riquelme ME. Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations. Arthritis Rheum. 2012 Nov; 64(11):3687-94. PMID: 22886787; PMCID: PMC3485439.
    71. Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am J Hum Genet. 2012 Nov 02; 91(5):778-93. PMID: 23084292; PMCID: PMC3487133.
    72. Manjarrez-Orduño N, Marasco E, Chung SA, Katz MS, Kiridly JF, Simpfendorfer KR, Freudenberg J, Ballard DH, Nashi E, Hopkins TJ, Cunninghame Graham DS, Lee AT, Coenen MJ, Franke B, Swinkels DW, Graham RR, Kimberly RP, Gaffney PM, Vyse TJ, Behrens TW, Criswell L, Diamond B, Gregersen PK. CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation. Nat Genet. 2012 Nov; 44(11):1227-30. PMID: 23042117; PMCID: PMC3715052.
    73. Richman IB, Taylor KE, Chung SA, Trupin L, Petri M, Yelin E, Graham RR, Lee A, Behrens TW, Gregersen PK, Seldin MF, Criswell L. European genetic ancestry is associated with a decreased risk of lupus nephritis. Arthritis Rheum. 2012 Oct; 64(10):3374-82. PMID: 23023776; PMCID: PMC3865923.
    74. Murray SG, Yazdany J, Kaiser R, Criswell L, Trupin L, Yelin EH, Katz PP, Julian LJ. Cardiovascular disease and cognitive dysfunction in systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2012 Sep; 64(9):1328-33. PMID: 22549897; PMCID: PMC3705733.
    75. Kaufman KM, Zhao J, Kelly JA, Hughes T, Adler A, Sanchez E, Ojwang JO, Langefeld CD, Ziegler JT, Williams AH, Comeau ME, Marion MC, Glenn SB, Cantor RM, Grossman JM, Hahn BH, Song YW, Yu CY, James JA, Guthridge JM, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Anaya JM, Boackle SA, Stevens AM, Freedman BI, Criswell L, Pons Estel BA. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44. PMID: 22904263; PMCID: PMC3567234.
    76. Sacre K, Criswell L, McCune JM. Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus. Arthritis Res Ther. 2012 Jun 27; 14(3):R155. PMID: 22734582; PMCID: PMC3446541.
    77. Kaiser R, Li Y, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri MA, Kimberly RP, Taylor KE, Criswell L. Genetic risk factors for thrombosis in systemic lupus erythematosus. J Rheumatol. 2012 Aug; 39(8):1603-10. PMID: 22707612; PMCID: PMC3640619.
    78. Yazdany J, Trupin L, Tonner C, Dudley RA, Zell J, Panopalis P, Schmajuk G, Julian L, Katz P, Criswell L, Yelin E. Quality of care in systemic lupus erythematosus: application of quality measures to understand gaps in care. J Gen Intern Med. 2012 Oct; 27(10):1326-33. PMID: 22588825; PMCID: PMC3445683.
    79. Kim K, Brown EE, Choi CB, Alarcón-Riquelme ME. Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis. 2012 Nov; 71(11):1809-14. PMID: 22523428; PMCID: PMC3466387.
    80. Katz P, Julian L, Tonner MC, Yazdany J, Trupin L, Yelin E, Criswell L. Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2012 Apr; 64(4):502-10. PMID: 22337564; PMCID: PMC3315616.
    81. Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, Adler AJ, Li H, Rasmussen A, Williams AH, Ziegler J, Comeau ME, Marion M, Wakeland BE, Liang C, Ramos PS, Grundahl KM, Gallant CJ, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Bae SC, Boackle SA, Brown EE, Chang DM, Cho SK, Criswell L, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Kim JH, Martin J, Merrill JT, Niewold TB, Park SY, Petri MA, Pons-Estel BA, Ramsey-Goldman R, Reveille JD, Scofield RH, Song YW, Stevens AM, Tsao BP, Vila LM, Vyse TJ, Yu CY, Guthridge JM, Kaufman KM, Harley JB, Wakeland EK, Langefeld CD, Gaffney PM, Montgomery CG, Moser KL. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012 Apr 06; 90(4):648-60. PMID: 22464253; PMCID: PMC3322228.
    82. Julian LJ, Yazdany J, Trupin L, Criswell L, Yelin E, Katz PP. Validity of brief screening tools for cognitive impairment in rheumatoid arthritis and systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2012 Mar; 64(3):448-54. PMID: 22162414; PMCID: PMC3705711.
    83. Hughes T, Adler A, Kelly JA, Kaufman KM, Williams AH, Langefeld CD, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Boackle SA, Stevens AM, Reveille JD, Sanchez E, Martín J, Niewold TB, Vilá LM, Scofield RH, Gilkeson GS, Gaffney PM, Criswell L, Moser KL, Merrill JT, Jacob CO, Tsao BP, James JA, Vyse TJ, Alarcón-Riquelme ME. Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum. 2012 Feb; 64(2):485-92. PMID: 21952918; PMCID: PMC3268866.
    84. Yelin E, Tonner C, Trupin L, Gansky SA, Julian L, Katz P, Yazdany J, Kaiser R, Criswell L. Longitudinal study of the impact of incident organ manifestations and increased disease activity on work loss among persons with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2012 Feb; 64(2):169-75. PMID: 22006458; PMCID: PMC3263318.
    85. Richard-Miceli C, Criswell L. Emerging patterns of genetic overlap across autoimmune disorders. Genome Med. 2012 Jan 27; 4(1):6. PMID: 22284131; PMCID: PMC3334554.
    86. Malladi AS, Sack KE, Shiboski SC, Shiboski CH, Baer AN, Banushree R, Dong Y, Helin P, Kirkham BW, Li M, Sugai S, Umehara H, Vivino FB, Vollenweider CF, Zhang W, Zhao Y, Greenspan JS, Daniels TE, Criswell L. Primary Sjögren's syndrome as a systemic disease: a study of participants enrolled in an international Sjögren's syndrome registry. Arthritis Care Res (Hoboken). 2012 Jun; 64(6):911-8. PMID: 22238244; PMCID: PMC3595164.
    87. Namjou B, Choi CB, Harley IT, Alarcón-Riquelme ME. Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum. 2012 Jun; 64(6):1960-9. PMID: 22231568; PMCID: PMC3380425.
    88. Ramos PS, Criswell L, Moser KL, Comeau ME, Williams AH, Pajewski NM, Chung SA, Graham RR, Zidovetzki R, Kelly JA, Kaufman KM, Jacob CO, Vyse TJ, Tsao BP, Kimberly RP, Gaffney PM, Alarcón-Riquelme ME, Harley JB, Langefeld CD. A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap. PLoS Genet. 2011 Dec; 7(12):e1002406. PMID: 22174698; PMCID: PMC3234215.
    89. Hughes T, Adler A, Merrill JT, Kelly JA, Kaufman KM, Williams A, Langefeld CD, Gilkeson GS, Sanchez E, Martin J, Boackle SA, Stevens AM, Alarcón GS, Niewold TB, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Criswell L, Vilá LM, Jacob CO, Gaffney PM, Moser KL, Vyse TJ, Alarcón-Riquelme ME. Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis. 2012 May; 71(5):694-9. PMID: 22110124; PMCID: PMC3324666.
    90. Cunninghame Graham DS, Morris DL, Bhangale TR, Criswell L, Syvänen AC, Rönnblom L, Behrens TW, Graham RR, Vyse TJ. Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. PLoS Genet. 2011 Oct; 7(10):e1002341. PMID: 22046141; PMCID: PMC3203198.
    91. Hammer GE, Turer EE, Taylor KE, Fang CJ, Advincula R, Oshima S, Barrera J, Huang EJ, Hou B, Malynn BA, Reizis B, DeFranco A, Criswell L, Nakamura MC, Ma A. Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. Nat Immunol. 2011 Oct 23; 12(12):1184-93. PMID: 22019834.
      View in: PubMed
    92. Plenge RM, Bridges SL, Huizinga TW, Criswell L, Gregersen PK. Recommendations for publication of genetic association studies in Arthritis & Rheumatism. Arthritis Rheum. 2011 Oct; 63(10):2839-47. PMID: 21702018.
      View in: PubMed
    93. Katz P, Yazdany J, Julian L, Trupin L, Margaretten M, Yelin E, Criswell L. Impact of obesity on functioning among women with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011 Oct; 63(10):1357-64. PMID: 21702085; PMCID: PMC3183275.
    94. Tan W, Sunahori K, Zhao J, Deng Y, Kaufman KM, Kelly JA, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Bae SC, Lee JH, Lee JS, Chang DM, Song YW, Yu CY, Kimberly RP, Edberg JC, Brown EE, Petri MA, Ramsey-Goldman R, Vilá LM, Reveille JD, Alarcón-Riquelme ME, Harley JB, Boackle SA, Stevens AM, Scofield RH, Merrill JT, Freedman BI, Anaya JM, Criswell L, Jacob CO, Vyse TJ, Niewold TB, Gaffney PM, Moser KL, Gilkeson GS, Kamen DL, James JA, Grossman JM, Hahn BH, Tsokos GC, Tsao BP, Alarcón GS. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum. 2011 Sep; 63(9):2755-63. PMID: 21590681.
      View in: PubMed
    95. Yazdany J, Trupin L, Gansky SA, Dall'era M, Yelin EH, Criswell L, Katz PP. Brief index of lupus damage: a patient-reported measure of damage in systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011 Aug; 63(8):1170-7. PMID: 21584946; PMCID: PMC3149719.
    96. Ramos PS, Williams AH, Ziegler JT, Comeau ME, Guy RT, Lessard CJ, Li H, Edberg JC, Zidovetzki R, Criswell L, Gaffney PM, Graham DC, Graham RR, Kelly JA, Kaufman KM, Brown EE, Alarcón GS, Petri MA, Reveille JD, McGwin G, Vilá LM, Ramsey-Goldman R, Jacob CO, Vyse TJ, Tsao BP, Harley JB, Kimberly RP, Alarcón-Riquelme ME, Langefeld CD, Moser KL. Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus. Arthritis Rheum. 2011 Jul; 63(7):2049-57. PMID: 21437871.
      View in: PubMed
    97. Daniels TE, Cox D, Shiboski CH, Schiødt M, Wu A, Lanfranchi H, Umehara H, Zhao Y, Challacombe S, Lam MY, De Souza Y, Schiødt J, Holm H, Bisio PA, Gandolfo MS, Sawaki T, Li M, Zhang W, Varghese-Jacob B, Ibsen P, Keszler A, Kurose N, Nojima T, Odell E, Criswell L, Jordan R, Greenspan JS. Associations between salivary gland histopathologic diagnoses and phenotypic features of Sjögren's syndrome among 1,726 registry participants. Arthritis Rheum. 2011 Jul; 63(7):2021-30. PMID: 21480190; PMCID: PMC3128201.
    98. Sanchez E, Nadig A, Richardson BC, Freedman BI, Kaufman KM, Kelly JA, Niewold TB, Kamen DL, Gilkeson GS, Ziegler JT, Langefeld CD, Alarcón GS, Edberg JC, Ramsey-Goldman R, Petri M, Brown EE, Kimberly RP, Reveille JD, Vilá LM, Merrill JT, Anaya JM, James JA, Pons-Estel BA, Martin J, Park SY, Bang SY, Bae SC, Moser KL, Vyse TJ, Criswell L, Gaffney PM, Tsao BP, Jacob CO, Harley JB, Alarcón-Riquelme ME. Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Ann Rheum Dis. 2011 Oct; 70(10):1752-7. PMID: 21719445.
      View in: PubMed
    99. Julian LJ, Gregorich SE, Tonner C, Yazdany J, Trupin L, Criswell L, Yelin E, Katz PP. Using the Center for Epidemiologic Studies Depression Scale to screen for depression in systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011 Jun; 63(6):884-90. PMID: 21312347; PMCID: PMC3719846.
    100. Zhao J, Wu H, Khosravi M, Cui H, Qian X, Kelly JA, Kaufman KM, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Adler A, Glenn SB, Alarcón-Riquelme ME. Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet. 2011 May; 7(5):e1002079. PMID: 21637784; PMCID: PMC3102741.
    101. Julian LJ, Tonner C, Yelin E, Yazdany J, Trupin L, Criswell L, Katz PP. Cardiovascular and disease-related predictors of depression in systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011 Apr; 63(4):542-9. PMID: 21452266; PMCID: PMC3713607.
    102. Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, Jacob CO, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet. 2011 Mar; 7(3):e1001323. PMID: 21408207; PMCID: PMC3048371.
    103. Adrianto I, Wen F, Templeton A, Wiley G, King JB, Lessard CJ, Bates JS, Hu Y, Kelly JA, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011 Mar; 43(3):253-8. PMID: 21336280; PMCID: PMC3103780.
    104. Taylor KE, Chung SA, Graham RR, Ortmann WA, Lee AT, Langefeld CD, Jacob CO, Kamboh MI, Alarcón-Riquelme ME, Tsao BP, Moser KL, Gaffney PM, Harley JB, Petri M, Manzi S, Gregersen PK, Behrens TW, Criswell L. Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes. PLoS Genet. 2011 Feb; 7(2):e1001311. PMID: 21379322; PMCID: PMC3040652.
    105. Katz P, Gregorich S, Yazdany J, Trupin L, Julian L, Yelin E, Criswell L. Obesity and its measurement in a community-based sample of women with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011 Feb; 63(2):261-8. PMID: 20824801; PMCID: PMC3010264.
    106. Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, Adler A, Williams AH, Gallant CJ. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet. 2011 Jan 07; 88(1):83-91. PMID: 21194677; PMCID: PMC3014359.
    107. Sandling JK, Garnier S, Sigurdsson S, Wang C, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Mälarstig A, Strawbridge RJ, Hamsten A, Criswell L, Graham RR, Behrens TW, Eloranta ML, Alm G, Rönnblom L, Syvänen AC. A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE. Eur J Hum Genet. 2011 Apr; 19(4):479-84. PMID: 21179067; PMCID: PMC3060320.
    108. Mikuls TR, Gould KA, Bynoté KK, Yu F, Levan TD, Thiele GM, Michaud KD, O'Dell JR, Reimold AM, Hooker R, Caplan L, Johnson DS, Kerr G, Richards JS, Cannon GW, Criswell L, Noble JA, Bridges SL, Hughes L, Gregersen PK. Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study. Arthritis Res Ther. 2010; 12(6):R213. PMID: 21087494; PMCID: PMC3046521.
    109. Hersh AO, Trupin L, Yazdany J, Panopalis P, Julian L, Katz P, Criswell L, Yelin E. Childhood-onset disease as a predictor of mortality in an adult cohort of patients with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Aug; 62(8):1152-9. PMID: 20235215; PMCID: PMC3755501.
    110. Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, Nititham J, Hughes LB, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedrén S, Ding B, Guiducci C, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Herenius M, Weinblatt ME, Shadick NA, Worthington J, Batliwalla F, Kern M, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, Seldin MF, Moreland LW, Behrens TW, Allaart CF, Criswell L, Huizinga TW, Tak PP, Bridges SL, Toes RE, Barton A, Klareskog L, Gregersen PK, Karlson EW, Plenge RM. Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy. Arthritis Rheum. 2010 Jul; 62(7):1849-61. PMID: 20309874; PMCID: PMC3652476.
    111. Bronson PG, Komorowski LK, Ramsay PP, May SL, Noble J, Lane JA, Thomson G, Claas FH, Seldin MF, Kelly JA, Harley JB, Moser KL, Gaffney PM, Behrens T, Criswell L, Barcellos LF. Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus. Arthritis Rheum. 2010 Jun; 62(6):1712-7. PMID: 20191587; PMCID: PMC2948464.
    112. Tonner C, Trupin L, Yazdany J, Criswell L, Katz P, Yelin E. Role of community and individual characteristics in physician visits for persons with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Jun; 62(6):888-95. PMID: 20535800; PMCID: PMC3715029.
    113. Yazdany J, Tonner C, Trupin L, Panopalis P, Gillis JZ, Hersh AO, Julian LJ, Katz PP, Criswell L, Yelin EH. Provision of preventive health care in systemic lupus erythematosus: data from a large observational cohort study. Arthritis Res Ther. 2010; 12(3):R84. PMID: 20462444; PMCID: PMC2911868.
    114. Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet. 2010 Jun; 42(6):508-14. PMID: 20453842; PMCID: PMC4243840.
    115. Flesher DL, Sun X, Behrens TW, Graham RR, Criswell L. Recent advances in the genetics of systemic lupus erythematosus. Expert Rev Clin Immunol. 2010 May; 6(3):461-79. PMID: 20441431; PMCID: PMC2897739.
    116. Panopalis P, Gillis JZ, Yazdany J, Trupin L, Hersh A, Julian L, Criswell L, Katz P, Yelin E. Frequent use of the emergency department among persons with systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2010 Mar; 62(3):401-8. PMID: 20391487; PMCID: PMC3759153.
    117. Kaiser R, Criswell L. Genetics research in systemic lupus erythematosus for clinicians: methodology, progress, and controversies. Curr Opin Rheumatol. 2010 Mar; 22(2):119-25. PMID: 20035223.
      View in: PubMed
    118. Criswell L. Gene discovery in rheumatoid arthritis highlights the CD40/NF-kappaB signaling pathway in disease pathogenesis. Immunol Rev. 2010 Jan; 233(1):55-61. PMID: 20192992.
      View in: PubMed
    119. Amos CI, Chen WV, Seldin MF, Remmers EF, Taylor KE, Criswell L, Lee AT, Plenge RM, Kastner DL, Gregersen PK. Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data. BMC Proc. 2009 Dec 15; 3 Suppl 7:S2. PMID: 20018009; PMCID: PMC2795916.
    120. Taylor KE, Criswell L. Conditional analysis of the major histocompatibility complex in rheumatoid arthritis. BMC Proc. 2009 Dec 15; 3 Suppl 7:S36. PMID: 20018027; PMCID: PMC2795934.
    121. Pavy S, Toonen EJ, Miceli-Richard C, Barrera P, van Riel PL, Criswell L, Mariette X, Coenen MJ. Tumour necrosis factor alpha -308G->A polymorphism is not associated with response to TNFalpha blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis. Ann Rheum Dis. 2010 Jun; 69(6):1022-8. PMID: 19966089.
      View in: PubMed
    122. Barton JL, Criswell L, Kaiser R, Chen YH, Schillinger D. Systematic review and metaanalysis of patient self-report versus trained assessor joint counts in rheumatoid arthritis. J Rheumatol. 2009 Dec; 36(12):2635-41. PMID: 19918045; PMCID: PMC2874463.
    123. Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet. 2009 Dec; 41(12):1313-8. PMID: 19898481; PMCID: PMC3142887.
    124. Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell L. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. PLoS Genet. 2009 Oct; 5(10):e1000696. PMID: 19851445; PMCID: PMC2758598.
    125. Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Rantapää-Dahlqvist S, Baechler EC, Brown EE, Alarcón GS, Edberg JC, Ramsey-Goldman R, McGwin G, Reveille JD, Vilá LM, Kimberly RP, Manzi S, Petri MA, Lee A, Gregersen PK, Seldin MF, Rönnblom L, Criswell L, Syvänen AC, Behrens TW, Graham RR. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet. 2009 Nov; 41(11):1228-33. PMID: 19838195; PMCID: PMC2925843.
    126. Chung SA, Tian C, Taylor KE, Lee AT, Ortmann WA, Hom G, Graham RR, Nititham J, Kelly JA, Morrisey J, Wu H, Yin H, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL, Manzi S, Petri M, Gregersen PK, Langefeld CD, Behrens TW, Seldin MF, Criswell L. European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus. Arthritis Rheum. 2009 Aug; 60(8):2448-56. PMID: 19644962; PMCID: PMC2739103.
    127. Bachen EA, Chesney MA, Criswell L. Prevalence of mood and anxiety disorders in women with systemic lupus erythematosus. Arthritis Rheum. 2009 Jun 15; 61(6):822-9. PMID: 19479699; PMCID: PMC2763591.
    128. Gregersen PK, Amos CI, Lee AT, Lu Y, Remmers EF, Kastner DL, Seldin MF, Criswell L, Plenge RM, Holers VM, Mikuls TR, Sokka T, Moreland LW, Bridges SL, Xie G, Begovich AB, Siminovitch KA. REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet. 2009 Jul; 41(7):820-3. PMID: 19503088; PMCID: PMC2705058.
    129. Daniels TE, Criswell L, Shiboski C, Shiboski S, Lanfranchi H, Dong Y, Schiødt M, Umehara H, Sugai S, Challacombe S, Greenspan JS. An early view of the international Sjögren's syndrome registry. Arthritis Rheum. 2009 May 15; 61(5):711-4. PMID: 19405009; PMCID: PMC2819471.
    130. Liu K, Li QZ, Delgado-Vega AM, Abelson AK, Sánchez E, Kelly JA, Li L, Liu Y, Zhou J, Yan M, Ye Q, Liu S, Xie C, Zhou XJ, Chung SA, Pons-Estel B, Witte T, de Ramón E, Bae SC, Barizzone N, Sebastiani GD, Merrill JT, Gregersen PK, Gilkeson GG, Kimberly RP, Vyse TJ, Kim I, D'Alfonso S, Martin J, Harley JB, Criswell L. Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. J Clin Invest. 2009 Apr; 119(4):911-23. PMID: 19307730; PMCID: PMC2662554.
    131. Cui J, Taylor KE, Destefano AL, Criswell L, Izmailova ES, Parker A, Roubenoff R, Plenge RM, Weinblatt ME, Shadick NA, Karlson EW. Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis. Mol Med. 2009 May-Jun; 15(5-6):136-43. PMID: 19287509.
      View in: PubMed
    132. Julian LJ, Yelin E, Yazdany J, Panopalis P, Trupin L, Criswell L, Katz P. Depression, medication adherence, and service utilization in systemic lupus erythematosus. Arthritis Rheum. 2009 Feb 15; 61(2):240-6. PMID: 19177526; PMCID: PMC2875189.
    133. Yelin E, Tonner C, Trupin L, Panopalis P, Yazdany J, Julian L, Katz P, Criswell L. Work loss and work entry among persons with systemic lupus erythematosus: comparisons with a national matched sample. Arthritis Rheum. 2009 Feb 15; 61(2):247-58. PMID: 19177546; PMCID: PMC2875188.
    134. Hersh AO, von Scheven E, Yazdany J, Panopalis P, Trupin L, Julian L, Katz P, Criswell L, Yelin E. Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosus. Arthritis Rheum. 2009 Jan 15; 61(1):13-20. PMID: 19116979; PMCID: PMC2875186.
    135. Korman BD, Seldin MF, Taylor KE, Le JM, Lee AT, Plenge RM, Amos CI, Criswell L, Gregersen PK, Kastner DL, Remmers EF. The chromosome 7q region association with rheumatoid arthritis in females in a British population is not replicated in a North American case-control series. Arthritis Rheum. 2009 Jan; 60(1):47-52. PMID: 19116934; PMCID: PMC2741408.
    136. Panopalis P, Yazdany J, Gillis JZ, Julian L, Trupin L, Hersh AO, Criswell L, Katz P, Yelin E. Health care costs and costs associated with changes in work productivity among persons with systemic lupus erythematosus. Arthritis Rheum. 2008 Dec 15; 59(12):1788-95. PMID: 19035422; PMCID: PMC2875149.
    137. Raychaudhuri S, Remmers EF, Lee AT, Hackett R, Guiducci C, Burtt NP, Gianniny L, Korman BD, Padyukov L, Kurreeman FA, Chang M, Catanese JJ, Ding B, Wong S, van der Helm-van Mil AH, Neale BM, Coblyn J, Cui J, Tak PP, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Criswell L, Amos CI, Seldin MF, Kastner DL, Ardlie KG, Alfredsson L, Costenbader KH, Altshuler D, Huizinga TW, Shadick NA, Weinblatt ME, de Vries N, Worthington J, Seielstad M, Toes RE, Karlson EW, Begovich AB, Klareskog L, Gregersen PK, Daly MJ, Plenge RM. Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet. 2008 Oct; 40(10):1216-23. PMID: 18794853.
      View in: PubMed
    138. Forabosco P, Bouzigon E, Ng MY, Hermanowski J, Fisher SA, Criswell L, Lewis CM. Meta-analysis of genome-wide linkage studies across autoimmune diseases. Eur J Hum Genet. 2009 Feb; 17(2):236-43. PMID: 18781189; PMCID: PMC2986058.
    139. Musone SL, Taylor KE, Lu TT, Nititham J, Ferreira RC, Ortmann W, Shifrin N, Petri MA, Kamboh MI, Manzi S, Seldin MF, Gregersen PK, Behrens TW, Ma A, Kwok PY, Criswell L. Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nat Genet. 2008 Sep; 40(9):1062-4. PMID: 19165919; PMCID: PMC3897246.
    140. Trupin L, Tonner MC, Yazdany J, Julian LJ, Criswell L, Katz PP, Yelin E. The role of neighborhood and individual socioeconomic status in outcomes of systemic lupus erythematosus. J Rheumatol. 2008 Sep; 35(9):1782-8. PMID: 18634153; PMCID: PMC2875144.
    141. Chang M, Rowland CM, Garcia VE, Schrodi SJ, Catanese JJ, van der Helm-van Mil AH, Ardlie KG, Amos CI, Criswell L, Kastner DL, Gregersen PK, Kurreeman FA, Toes RE, Huizinga TW, Seldin MF, Begovich AB. A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2. PLoS Genet. 2008 Jun 27; 4(6):e1000107. PMID: 18648537; PMCID: PMC2481282.
    142. Chang M, Saiki RK, Cantanese JJ, Lew D, van der Helm-van Mil AH, Toes RE, Huizinga TW, Ardlie KG, Criswell L, Seldin MF, Amos CI, Kastner DL, Gregersen PK, Schrodi SJ, Begovich AB. The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritis. Arthritis Rheum. 2008 Jun; 58(6):1877-81. PMID: 18512797.
      View in: PubMed
    143. Taylor KE, Remmers EF, Lee AT, Ortmann WA, Plenge RM, Tian C, Chung SA, Nititham J, Hom G, Kao AH, Demirci FY, Kamboh MI, Petri M, Manzi S, Kastner DL, Seldin MF, Gregersen PK, Behrens TW, Criswell L. Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus. PLoS Genet. 2008 May 30; 4(5):e1000084. PMID: 18516230; PMCID: PMC2377340.
    144. Lee HS, Lee AT, Criswell L, Seldin MF, Amos CI, Carulli JP, Navarrete C, Remmers EF, Kastner DL, Plenge RM, Li W, Gregersen PK. Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus. Mol Med. 2008 May-Jun; 14(5-6):293-300. PMID: 18309376; PMCID: PMC2255558.
    145. Plenge RM, Criswell L. Genetic variants that predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis: current challenges and future directions. Curr Opin Rheumatol. 2008 Mar; 20(2):145-52. PMID: 18349743.
      View in: PubMed
    146. Criswell L, Seldin MF. Admixed populations and autoimmunity. Arthritis Rheum. 2008 Feb; 58(2):335-7. PMID: 18240252.
      View in: PubMed
    147. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet. 2008 Feb; 40(2):204-10. PMID: 18204446.
      View in: PubMed
    148. Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, Tian C, Gunnarsson I, Bengtsson AA, Rantapää-Dahlqvist S, Petri M, Manzi S, Seldin MF, Rönnblom L, Syvänen AC, Criswell L, Gregersen PK, Behrens TW. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med. 2008 Feb 28; 358(9):900-9. PMID: 18204098.
      View in: PubMed
    149. Criswell L. The genetic contribution to systemic lupus erythematosus. Bull NYU Hosp Jt Dis. 2008; 66(3):176-83. PMID: 18937628.
      View in: PubMed
    150. Taylor KE, Chen W, Amos CI, Criswell L. Genome-wide single-nucleotide polymorphism linkage analyses of quantitative rheumatoid arthritis phenotypes in Caucasian NARAC families. BMC Proc. 2007; 1 Suppl 1:S105. PMID: 18466445; PMCID: PMC2367581.
    151. Amos CI, Chen WV, Remmers E, Siminovitch KA, Seldin MF, Criswell L, Lee AT, John S, Shephard ND, Worthington J, Cornelis F, Plenge RM, Begovich AB, Dyer TD, Kastner DL, Gregersen PK. Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits. BMC Proc. 2007; 1 Suppl 1:S3. PMID: 18466527; PMCID: PMC2367518.
    152. Panopalis P, Julian L, Yazdany J, Gillis JZ, Trupin L, Hersh A, Criswell L, Katz P, Yelin E. Impact of memory impairment on employment status in persons with systemic lupus erythematosus. Arthritis Rheum. 2007 Dec 15; 57(8):1453-60. PMID: 18050187; PMCID: PMC2875137.
    153. Chung SA, Criswell L. PTPN22: its role in SLE and autoimmunity. Autoimmunity. 2007 Dec; 40(8):582-90. PMID: 18075792; PMCID: PMC2875134.
    154. Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, Behrens TW, de Bakker PI, Le JM, Lee HS, Batliwalla F, Li W, Masters SL, Booty MG, Carulli JP, Padyukov L, Alfredsson L, Klareskog L, Chen WV, Amos CI, Criswell L, Seldin MF, Kastner DL, Gregersen PK. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med. 2007 Sep 06; 357(10):977-86. PMID: 17804842; PMCID: PMC2630215.
    155. Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, Carulli JP, Beckman EM, Altshuler D, Alfredsson L, Criswell L, Amos CI, Seldin MF, Kastner DL, Klareskog L, Gregersen PK. TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med. 2007 Sep 20; 357(12):1199-209. PMID: 17804836; PMCID: PMC2636867.
    156. Kinder BW, Freemer MM, King TE, Lum RF, Nititham J, Taylor K, Edberg JC, Bridges SL, Criswell L. Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus. Arthritis Rheum. 2007 Aug; 56(8):2679-86. PMID: 17665457; PMCID: PMC2875177.
    157. Lee HS, Irigoyen P, Kern M, Lee A, Batliwalla F, Khalili H, Wolfe F, Lum RF, Massarotti E, Weisman M, Bombardier C, Karlson EW, Criswell L, Vlietinck R, Gregersen PK. Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts. Arthritis Rheum. 2007 Jun; 56(6):1745-53. PMID: 17530703.
      View in: PubMed
    158. Yazdany J, Gillis JZ, Trupin L, Katz P, Panopalis P, Criswell L, Yelin E. Association of socioeconomic and demographic factors with utilization of rheumatology subspecialty care in systemic lupus erythematosus. Arthritis Rheum. 2007 May 15; 57(4):593-600. PMID: 17471526; PMCID: PMC2875170.
    159. Gillis JZ, Yazdany J, Trupin L, Julian L, Panopalis P, Criswell L, Katz P, Yelin E. Medicaid and access to care among persons with systemic lupus erythematosus. Arthritis Rheum. 2007 May 15; 57(4):601-7. PMID: 17471527; PMCID: PMC2875126.
    160. Yelin E, Trupin L, Katz P, Criswell L, Yazdany J, Gillis J, Panopalis P. Impact of health maintenance organizations and fee-for-service on health care utilization among people with systemic lupus erythematosus. Arthritis Rheum. 2007 Apr 15; 57(3):508-15. PMID: 17394180; PMCID: PMC2875127.
    161. Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Rönnblom L, Nordmark G, Gregersen PK, Moser K, Gaffney PM, Criswell L, Vyse TJ, Syvänen AC, Bohjanen PR, Daly MJ, Behrens TW, Altshuler D. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6758-63. PMID: 17412832; PMCID: PMC1847749.
    162. Graham RR, Ortmann W, Rodine P, Espe K, Langefeld C, Lange E, Williams A, Beck S, Kyogoku C, Moser K, Gaffney P, Gregersen PK, Criswell L, Harley JB, Behrens TW. Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE. Eur J Hum Genet. 2007 Aug; 15(8):823-30. PMID: 17406641.
      View in: PubMed
    163. Yelin E, Trupin L, Katz P, Criswell L, Yazdany J, Gillis J, Panopalis P. Work dynamics among persons with systemic lupus erythematosus. Arthritis Rheum. 2007 Feb 15; 57(1):56-63. PMID: 17266065; PMCID: PMC2875125.
    164. Criswell L, Chen WV, Jawaheer D, Lum RF, Wener MH, Gu X, Gregersen PK, Amos CI. Dissecting the heterogeneity of rheumatoid arthritis through linkage analysis of quantitative traits. Arthritis Rheum. 2007 Jan; 56(1):58-68. PMID: 17195208.
      View in: PubMed
    165. Deighton C, Criswell L. Recent advances in the genetics of rheumatoid arthritis. Curr Rheumatol Rep. 2006 Oct; 8(5):394-400. PMID: 16973114.
      View in: PubMed
    166. Jawaheer D, Lum RF, Gregersen PK, Criswell L. Influence of male sex on disease phenotype in familial rheumatoid arthritis. Arthritis Rheum. 2006 Oct; 54(10):3087-94. PMID: 17009227.
      View in: PubMed
    167. Janssens AC, Steyerberg EW, Jiang Y, Habbema JD, Van Duijn CM, Criswell L. Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile. J Rheumatol. 2006 Dec; 33(12):2383-9. PMID: 16960929.
      View in: PubMed
    168. Criswell L, Saag KG, Mikuls TR, Cerhan JR, Merlino LA, Lum RF, Pfeiffer KA, Woehl B, Seldin MF. Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women. Ann Rheum Dis. 2006 Sep; 65(9):1163-7. PMID: 16887863; PMCID: PMC1798304.
    169. Hu X, Chang M, Saiki RK, Cargill MA, Begovich AB, Ardlie KG, Criswell L, Seldin MF, Amos CI, Gregersen PK, Kastner DL, Remmers EF. The functional -169T-->C single-nucleotide polymorphism in FCRL3 is not associated with rheumatoid arthritis in white North Americans. Arthritis Rheum. 2006 Mar; 54(3):1022-5. PMID: 16508985.
      View in: PubMed
    170. Irigoyen P, Lee AT, Wener MH, Li W, Kern M, Batliwalla F, Lum RF, Massarotti E, Weisman M, Bombardier C, Remmers EF, Kastner DL, Seldin MF, Criswell L, Gregersen PK. Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles. Arthritis Rheum. 2005 Dec; 52(12):3813-8. PMID: 16320316.
      View in: PubMed
    171. Huizinga TW, Amos CI, van der Helm-van Mil AH, Chen W, van Gaalen FA, Jawaheer D, Schreuder GM, Wener M, Breedveld FC, Ahmad N, Lum RF, de Vries RR, Gregersen PK, Toes RE, Criswell L. Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis Rheum. 2005 Nov; 52(11):3433-8. PMID: 16255021.
      View in: PubMed
    172. Yang N, Li H, Criswell L, Gregersen PK, Alarcon-Riquelme ME, Kittles R, Shigeta R, Silva G, Patel PI, Belmont JW, Seldin MF. Examination of ancestry and ethnic affiliation using highly informative diallelic DNA markers: application to diverse and admixed populations and implications for clinical epidemiology and forensic medicine. Hum Genet. 2005 Dec; 118(3-4):382-92. PMID: 16193326.
      View in: PubMed
    173. Carlton VE, Hu X, Chokkalingam AP, Schrodi SJ, Brandon R, Alexander HC, Chang M, Catanese JJ, Leong DU, Ardlie KG, Kastner DL, Seldin MF, Criswell L, Gregersen PK, Beasley E, Thomson G, Amos CI, Begovich AB. PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. Am J Hum Genet. 2005 Oct; 77(4):567-81. PMID: 16175503; PMCID: PMC1275606.
    174. Criswell L, Pfeiffer KA, Lum RF, Gonzales B, Novitzke J, Kern M, Moser KL, Begovich AB, Carlton VE, Li W, Lee AT, Ortmann W, Behrens TW, Gregersen PK. Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes. Am J Hum Genet. 2005 Apr; 76(4):561-71. PMID: 15719322; PMCID: PMC1199294.
    175. Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell L. Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis. Arthritis Rheum. 2004 Nov; 50(11):3476-84. PMID: 15529352.
      View in: PubMed
    176. Criswell L, Lum RF, Turner KN, Woehl B, Zhu Y, Wang J, Tiwari HK, Edberg JC, Kimberly RP, Moreland LW, Seldin MF, Bridges SL. The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. Arthritis Rheum. 2004 Sep; 50(9):2750-6. PMID: 15457442.
      View in: PubMed
    177. Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, Ardlie KG, Huang Q, Smith AM, Spoerke JM, Conn MT, Chang M, Chang SY, Saiki RK, Catanese JJ, Leong DU, Garcia VE, McAllister LB, Jeffery DA, Lee AT, Batliwalla F, Remmers E, Criswell L, Seldin MF, Kastner DL, Amos CI, Sninsky JJ, Gregersen PK. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet. 2004 Aug; 75(2):330-7. PMID: 15208781; PMCID: PMC1216068.
    178. Criswell L. Familial clustering of disease features: implications for the etiology and investigation of systemic autoimmune disease. Arthritis Rheum. 2004 Jun; 50(6):1707-8. PMID: 15188345.
      View in: PubMed
    179. Seldin MF, Morii T, Collins-Schramm HE, Chima B, Kittles R, Criswell L, Li H. Putative ancestral origins of chromosomal segments in individual african americans: implications for admixture mapping. Genome Res. 2004 Jun; 14(6):1076-84. PMID: 15140829; PMCID: PMC419786.
    180. Jawaheer D, Lum RF, Amos CI, Gregersen PK, Criswell L. Clustering of disease features within 512 multicase rheumatoid arthritis families. Arthritis Rheum. 2004 Mar; 50(3):736-41. PMID: 15022313.
      View in: PubMed
    181. Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell L. Lack of association of the HLA-DRB1 shared epitope with rheumatoid nodules: an individual patient data meta-analysis of 3,272 Caucasian patients with rheumatoid arthritis. Arthritis Rheum. 2004 Mar; 50(3):753-62. PMID: 15022316.
      View in: PubMed
    182. Gorman JD, Lum RF, Chen JJ, Suarez-Almazor ME, Thomson G, Criswell L. Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients. Arthritis Rheum. 2004 Feb; 50(2):400-12. PMID: 14872482.
      View in: PubMed
    183. Merlino LA, Curtis J, Mikuls TR, Cerhan JR, Criswell L, Saag KG. Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study. Arthritis Rheum. 2004 Jan; 50(1):72-7. PMID: 14730601.
      View in: PubMed
    184. Prokunina L, Gunnarsson I, Sturfelt G, Truedsson L, Seligman VA, Olson JL, Seldin MF, Criswell L, Alarcón-Riquelme ME. The systemic lupus erythematosus-associated PDCD1 polymorphism PD1.3A in lupus nephritis. Arthritis Rheum. 2004 Jan; 50(1):327-8. PMID: 14730631.
      View in: PubMed
    185. Collins-Schramm HE, Chima B, Morii T, Wah K, Figueroa Y, Criswell L, Hanson RL, Knowler WC, Silva G, Belmont JW, Seldin MF. Mexican American ancestry-informative markers: examination of population structure and marker characteristics in European Americans, Mexican Americans, Amerindians and Asians. Hum Genet. 2004 Feb; 114(3):263-71. PMID: 14628215.
      View in: PubMed
    186. Merlino LA, Cerhan JR, Criswell L, Mikuls TR, Saag KG. Estrogen and other female reproductive risk factors are not strongly associated with the development of rheumatoid arthritis in elderly women. Semin Arthritis Rheum. 2003 Oct; 33(2):72-82. PMID: 14625816.
      View in: PubMed
    187. Collins-Schramm HE, Chima B, Operario DJ, Criswell L, Seldin MF. Markers informative for ancestry demonstrate consistent megabase-length linkage disequilibrium in the African American population. Hum Genet. 2003 Aug; 113(3):211-9. PMID: 12783300.
      View in: PubMed
    188. Mikuls T, Saag K, Criswell L, Merlino L, Cerhan JR. Health related quality of life in women with elderly onset rheumatoid arthritis. J Rheumatol. 2003 May; 30(5):952-7. PMID: 12734888.
      View in: PubMed
    189. Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Etzel C, Damle A, Xiao X, Chen D, Lum RF, Monteiro J, Kern M, Criswell L, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW, Bridges SL, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK. Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. Arthritis Rheum. 2003 Apr; 48(4):906-16. PMID: 12687532.
      View in: PubMed
    190. Hoaglund FT, Criswell L, Seldin MF. Gender and racial differences in rates of total hip replacement. J Bone Joint Surg Am. 2003 Mar; 85-A(3):569-70; author reply 570-1. PMID: 12637449.
      View in: PubMed
    191. Cerhan JR, Saag KG, Merlino LA, Mikuls TR, Criswell L. Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women. Am J Epidemiol. 2003 Feb 15; 157(4):345-54. PMID: 12578805.
      View in: PubMed
    192. Chen JJ, Mu H, Jiang Y, King MC, Thomson G, Criswell L. Clinical usefulness of genetic information for predicting radiographic damage in rheumatoid arthritis. J Rheumatol. 2002 Oct; 29(10):2068-73. PMID: 12375313.
      View in: PubMed
    193. Collins-Schramm HE, Kittles RA, Operario DJ, Weber JL, Criswell L, Cooper RS, Seldin MF. Markers that discriminate between European and African ancestry show limited variation within Africa. Hum Genet. 2002 Dec; 111(6):566-9. PMID: 12436248.
      View in: PubMed
    194. Jawaheer D, Li W, Graham RR, Chen W, Damle A, Xiao X, Monteiro J, Khalili H, Lee A, Lundsten R, Begovich A, Bugawan T, Erlich H, Elder JT, Criswell L, Seldin MF, Amos CI, Behrens TW, Gregersen PK. Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. Am J Hum Genet. 2002 Sep; 71(3):585-94. PMID: 12181776; PMCID: PMC449696.
    195. Seligman VA, Lum RF, Olson JL, Li H, Criswell L. Demographic differences in the development of lupus nephritis: a retrospective analysis. Am J Med. 2002 Jun 15; 112(9):726-9. PMID: 12079714.
      View in: PubMed
    196. Criswell L, Merlino LA, Cerhan JR, Mikuls TR, Mudano AS, Burma M, Folsom AR, Saag KG. Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal women: results from the Iowa Women's Health Study. Am J Med. 2002 Apr 15; 112(6):465-71. PMID: 11959057.
      View in: PubMed
    197. Gorman JD, Criswell L. The shared epitope and severity of rheumatoid arthritis. Rheum Dis Clin North Am. 2002 Feb; 28(1):59-78. PMID: 11840698.
      View in: PubMed
    198. Cerhan JR, Saag KG, Criswell L, Merlino LA, Mikuls TR. Blood transfusion, alcohol use, and anthropometric risk factors for rheumatoid arthritis in older women. J Rheumatol. 2002 Feb; 29(2):246-54. PMID: 11838841.
      View in: PubMed
    199. Mikuls TR, Cerhan JR, Criswell L, Merlino L, Mudano AS, Burma M, Folsom AR, Saag KG. Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health Study. Arthritis Rheum. 2002 Jan; 46(1):83-91. PMID: 11817612.
      View in: PubMed