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Nareg Roubinian, MD, MPH

Title(s)Associate Professor, Laboratory Medicine
SchoolSchool of Medicine
Phone415-476-4862
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    Collapse Research 
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    Effects of blood conservation and donor characteristics on transfused patient outcomes in a large community hospital network
    NIH R01HL126130Jun 1, 2016 - Feb 29, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bloch EM, Hull J, Green-Thompson R, Ingram C, Crookes RL, Fawcus S, Anthony J, Courtney L, Roubinian N, Jauregui A, Hilton JF, Murphy EL. Antenatal blood transfusion in South Africa: indications and practice in a high-HIV-prevalence setting. Transfusion. 2020 Jan 07. PMID: 31909499.
      View in: PubMed
    2. Bialkowski W, Tan S, Mast AE, Kiss JE, Kor D, Gottschall J, Wu Y, Roubinian N, Triulzi D, Kleinman S, Choi Y, Brambilla D, Zimrin A. Equivalent inpatient mortality among direct-acting oral anticoagulant and warfarin users presenting with major hemorrhage. Thromb Res. 2019 Nov 25; 185:109-118. PMID: 31794885.
      View in: PubMed
    3. Raisa Balbuena-Merle, Ronald G. Hauser, Matthew Karafin, Sylvia Tan, Bryan R Spencer, Nareg Roubinian, Yanyun Wu, Darrell Triulzi, Steven Kleinman, Jerry Gottschall, Christopher A. Tormey, Jeanne E. Hendrickson. The Presence and Persistence of Pregnancy-Associated Red Blood Cell Alloantibodies in Blood Donors. Blood. 2019 Nov 13; 134(Supplement_1):2452-2452.
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    4. Roubinian NH, Westlake M, St Lezin EM, Edgren G, Brambilla DJ, Lee C, Bruhn R, Cable RG, Triulzi DJ, Glynn SA, Kleinman S, Murphy EL. Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients. Transfusion. 2019 Nov; 59(11):3362-3370. PMID: 31602669.
      View in: PubMed
    5. Nareg H. Roubinian, Steven Kleinman, Edward L. Murphy, Simone A. Glynn, Gustaf Edgren. Methodological considerations for linked blood donor-component-recipient analyses in transfusion medicine research. ISBT Science Series. 2019 Aug 28.
      View in: Publisher Site
    6. Roubinian NH, Kanias T. Blood donor component-recipient linkages: is there fire where there is smoke? Transfusion. 2019 Aug; 59(8):2485-2488. PMID: 31374151.
      View in: PubMed
    7. Roubinian NH, Triulzi DJ. Transfusion-Associated Circulatory Overload and Transfusion-Related Acute Lung Injury: Etiology and Prevention. Hematol Oncol Clin North Am. 2019 Oct; 33(5):767-779. PMID: 31466603.
      View in: PubMed
    8. Roubinian NH, Plimier C, Woo JP, Lee C, Bruhn R, Liu VX, Escobar GJ, Kleinman SH, Triulzi DJ, Murphy EL, Busch MP. Effect of donor, component, and recipient characteristics on hemoglobin increments following red blood cell transfusion. Blood. 2019 Sep 26; 134(13):1003-1013. PMID: 31350268.
      View in: PubMed
    9. Sykes W, Van den Berg K, Jacobs G, Jauregui A, Roubinian N, Wiesner L, Maartens G, Swanevelder R, Custer B, Busch M, Jentsch U, Murphy EL, Vermeulen M. Discovery of False Elite Controllers: HIV Antibody-Positive RNA-Negative Blood Donors Found To Be on Antiretroviral Therapy. J Infect Dis. 2019 Jul 19; 220(4):643-647. PMID: 30950501.
      View in: PubMed
    10. Karafin MS, Bruhn R, Roubinian NH, Chowdhury D, Qu L, Snyder EL, Murphy EL, Brambilla D, Cable RG, Hilton JF, St Lezin E. The impact of recipient factors on the lower-than-expected hemoglobin increment in transfused outpatients with hematologic diseases. Transfusion. 2019 Aug; 59(8):2544-2550. PMID: 31270827.
      View in: PubMed
    11. Edgren G, Murphy EL, Brambilla DJ, Westlake M, Rostgaard K, Lee C, Cable RG, Triulzi D, Bruhn R, St Lezin EM, Erikstrup C, Ullum H, Glynn SA, Kleinman S, Hjalgrim H, Roubinian NH. Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients. JAMA. 2019 06 11; 321(22):2183-2192. PMID: 31184739.
      View in: PubMed
    12. Mark DG, Huang J, Plimier C, Reed ME, Escobar GJ, Vinson DR, Roubinian NH. Red blood cell transfusions for emergency department patients with gastrointestinal bleeding within an integrated health system. Am J Emerg Med. 2019 Jun 10. PMID: 31208843.
      View in: PubMed
    13. Roubinian N, Kleinman S. Building consensus: steps toward standardised haemovigilance reporting. Lancet Haematol. 2019 07; 6(7):e339-e340. PMID: 31080133.
      View in: PubMed
    14. Norris PJ, Schechtman K, Inglis HC, Adelman A, Heitman JW, Vilardi R, Shah A, Roubinian NH, Danesh A, Guiltinan AM, Keating SM, Lacroix J, Cohen MJ, Spinella PC. Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients. Transfusion. 2019 Apr; 59(4):1223-1232. PMID: 30882927.
      View in: PubMed
    15. Roubinian NH, Murphy EL, Mark DG, Triulzi DJ, Carson JL, Lee C, Kipnis P, Kleinman S, Liu VX, Escobar GJ. Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study. Ann Intern Med. 2019 01 15; 170(2):81-89. PMID: 30557414.
      View in: PubMed
    16. Roubinian N. TACO and TRALI: biology, risk factors, and prevention strategies. Hematology Am Soc Hematol Educ Program. 2018 11 30; 2018(1):585-594. PMID: 30570487.
      View in: PubMed
    17. Walter Bialkowski, Sylvia Tan, Alan E. Mast, Joseph Kiss, Daryl J. Kor, Jerome Gottschall, Yanyun Wu, Nareg H. Roubinian, Darrell Triulzi, Steven Kleinman, Young Choi, Donald Brambilla, Ann Butler Zimrin, The NHLBI Recipient Epidemiology and Donor Evaluation Study-III. Inpatient Mortality and Length of Stay Among Direct-Acting Oral Anticoagulant (DOAC) and Warfarin Users Presenting with Major Hemorrhage. Blood. 2018 Nov 29; 132(Supplement 1):2538-2538.
      View in: Publisher Site
    18. Karafin MS, Tan S, Tormey CA, Spencer BR, Hauser RG, Norris PJ, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Gottschall JL, Hendrickson JE. Prevalence and risk factors for RBC alloantibodies in blood donors in the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III). Transfusion. 2019 01; 59(1):217-225. PMID: 30427537.
      View in: PubMed
    19. Karafin MS, Westlake M, Hauser RG, Tormey CA, Norris PJ, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Hendrickson JE. Risk factors for red blood cell alloimmunization in the Recipient Epidemiology and Donor Evaluation Study (REDS-III) database. Br J Haematol. 2018 06; 181(5):672-681. PMID: 29675950.
      View in: PubMed
    20. Carson JL, Stanworth SJ, Alexander JH, Roubinian N, Fergusson DA, Triulzi DJ, Goodman SG, Rao SV, Doree C, Hebert PC. Clinical trials evaluating red blood cell transfusion thresholds: An updated systematic review and with additional focus on patients with cardiovascular disease. Am Heart J. 2018 06; 200:96-101. PMID: 29898855.
      View in: PubMed
    21. Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Michalkiewicz M, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL. Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload. Crit Care Med. 2018 04; 46(4):577-585. PMID: 29300236.
      View in: PubMed
    22. Gehrie EA, Roubinian NH, Chowdhury D, Brambilla DJ, Murphy EL, Gottschall JL, Wu Y, Ness PM, Strauss RG, Hendrickson JE. A multicentre study investigating vital sign changes occurring in complicated and uncomplicated transfusions. Vox Sang. 2018 Feb; 113(2):160-169. PMID: 29277907.
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    23. Karafin MS, Bruhn R, Westlake M, Sullivan MT, Bialkowski W, Edgren G, Roubinian NH, Hauser RG, Kor DJ, Fleischmann D, Gottschall JL, Murphy EL, Triulzi DJ. Demographic and epidemiologic characterization of transfusion recipients from four US regions: evidence from the REDS-III recipient database. Transfusion. 2017 12; 57(12):2903-2913. PMID: 29067705.
      View in: PubMed
    24. Roubinian N, Brambilla D, Murphy EL. Statistical Caution in Big Data Approaches to Transfusion Medicine Research. JAMA Intern Med. 2017 06 01; 177(6):860-861. PMID: 28437522.
      View in: PubMed
    25. Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL. Differentiating pulmonary transfusion reactions using recipient and transfusion factors. Transfusion. 2017 07; 57(7):1684-1690. PMID: 28470756.
      View in: PubMed
    26. Roubinian N, Murphy EL. Adjusting the Focus on Transfusion-associated Circulatory Overload. Anesthesiology. 2017 03; 126(3):363-365. PMID: 28072600.
      View in: PubMed
    27. Lori Sakoda, Khanh Thai, Nareg Roubinian, Carlos Iribarren, Catherine Schaefer, Neil Risch, Laurel Habel, Charles Quesenberry, Eric Jorgenson. OA04.06 Examining Pleiotropic Associations of Genetic Risk Variants for Chronic Obstructive Pulmonary Disease with Lung Cancer Risk. Journal of Thoracic Oncology. 2017 Jan 1; 12(1):s257-s258.
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    28. Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL. Incidence and clinical characteristics of transfusion-associated circulatory overload using an active surveillance algorithm. Vox Sang. 2017 Jan; 112(1):56-63. PMID: 28001313.
      View in: PubMed
    29. Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2016 Oct 12; 10:CD002042. PMID: 27731885.
      View in: PubMed
    30. Hendrickson JE, Roubinian NH, Chowdhury D, Brambilla D, Murphy EL, Wu Y, Ness PM, Gehrie EA, Snyder EL, George Hauser R, Gottschall JL, Kleinman S, Kakaiya R, Strauss RG. Incidence of transfusion reactions: a multicenter study utilizing systematic active surveillance and expert adjudication. Transfusion. 2016 Oct; 56(10):2587-2596. PMID: 27460200.
      View in: PubMed
    31. Roubinian N, Carson JL. Red Blood Cell Transfusion Strategies in Adult and Pediatric Patients with Malignancy. Hematol Oncol Clin North Am. 2016 06; 30(3):529-40. PMID: 27112994.
      View in: PubMed
    32. Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S. 2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium. Transfusion. 2015 Sep; 55(9):2282-90. PMID: 26260861.
      View in: PubMed
    33. Roubinian NH, Carson JL. Restrictive red blood cell transfusion strategies appear safe in most clinical settings. Evid Based Med. 2015 Oct; 20(5):170. PMID: 26220955.
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    34. Edward Murphy, Nareg Roubinian. Transfusion-associated circulatory overload (TACO): prevention, management, and patient outcomes. International Journal of Clinical Transfusion Medicine. 2015 Apr 1; Volume 3:17-28.
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    35. Roubinian NH, Looney MR, Kor DJ, Lowell CA, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson GA, Matthay MA, Toy P, Murphy EL. Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions. Transfusion. 2015 Aug; 55(8):1838-46. PMID: 25702590.
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    36. Roubinian NH, Leavitt AD. Shedding a little light on posttransfusion purpura. Transfusion. 2015 Feb; 55(2):232-4. PMID: 25683186.
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    37. Triulzi D, Gottschall J, Murphy E, Wu Y, Ness P, Kor D, Roubinian N, Fleischmann D, Chowdhury D, Brambilla D. A multicenter study of plasma use in the United States. Transfusion. 2015 Jun; 55(6):1313-9; quiz 1312. PMID: 25522888.
      View in: PubMed
    38. Roubinian NH, Escobar GJ, Liu V, Swain BE, Gardner MN, Kipnis P, Triulzi DJ, Gottschall JL, Wu Y, Carson JL, Kleinman SH, Murphy EL. Trends in red blood cell transfusion and 30-day mortality among hospitalized patients. Transfusion. 2014 Oct; 54(10 Pt 2):2678-86. PMID: 25135770.
      View in: PubMed
    39. Roubinian NH, Escobar GJ, Liu V, Gardner MN, Carson JL, Kleinman SH, Murphy EL. Decreased red blood cell use and mortality in hospitalized patients. JAMA Intern Med. 2014 Aug; 174(8):1405-7. PMID: 24978650.
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    40. Looney MR, Roubinian N, Gajic O, Gropper MA, Hubmayr RD, Lowell CA, Bacchetti P, Wilson G, Koenigsberg M, Lee DC, Wu P, Grimes B, Norris PJ, Murphy EL, Gandhi MJ, Winters JL, Mair DC, Schuller RM, Hirschler NV, Rosen RS, Matthay MA, Toy P. Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*. Crit Care Med. 2014 Jul; 42(7):1676-87. PMID: 24776608.
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    41. Roubinian NH, Murphy EL, Swain BE, Gardner MN, Liu V, Escobar GJ. Predicting red blood cell transfusion in hospitalized patients: role of hemoglobin level, comorbidities, and illness severity. BMC Health Serv Res. 2014 May 10; 14:213. PMID: 24884605.
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    42. Roubinian N, Blanc PD, Chen H. Response. Chest. 2013 Mar; 143(3):877. PMID: 23460178.
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    43. Roubinian N, Elliott CG, Barnett CF, Blanc PD, Chen J, De Marco T, Chen H. Effects of commercial air travel on patients with pulmonary hypertension air travel and pulmonary hypertension. Chest. 2012 Oct; 142(4):885-892. PMID: 22490871.
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    44. Wiita AP, Roubinian N, Khan Y, Chin-Hong PV, Singer JP, Golden JA, Miller S. Cytomegalovirus disease and infection in lung transplant recipients in the setting of planned indefinite valganciclovir prophylaxis. Transpl Infect Dis. 2012 Jun; 14(3):248-58. PMID: 22385394.
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    45. Greninger AL, Chen EC, Sittler T, Scheinerman A, Roubinian N, Yu G, Kim E, Pillai DR, Guyard C, Mazzulli T, Isa P, Arias CF, Hackett J, Schochetman G, Miller S, Tang P, Chiu CY. A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America. PLoS One. 2010 Oct 18; 5(10):e13381. PMID: 20976137.
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    46. Labelle AJ, Micek ST, Roubinian N, Kollef MH. Treatment-related risk factors for hospital mortality in Candida bloodstream infections. Crit Care Med. 2008 Nov; 36(11):2967-72. PMID: 18824910.
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    47. Micek ST, Kollef KE, Reichley RM, Roubinian N, Kollef MH. Health care-associated pneumonia and community-acquired pneumonia: a single-center experience. Antimicrob Agents Chemother. 2007 Oct; 51(10):3568-73. PMID: 17682100.
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    48. Micek ST, Roubinian N, Heuring T, Bode M, Williams J, Harrison C, Murphy T, Prentice D, Ruoff BE, Kollef MH. Before-after study of a standardized hospital order set for the management of septic shock. Crit Care Med. 2006 Nov; 34(11):2707-13. PMID: 16943733.
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    49. Nareg Roubinian, Donna Prentice, Marin Kollef, Tim Heuring, Meghan Bode, Theresa Murphy, Scott Micek, Jennifer Williams, Courtney Harrison. IMPLEMENTATION OF AN EARLY GOAL-DIRECTED SEPSIS PROTOCOL IN AN ACADEMIC EMERGENCY DEPARTMENT. Critical Care Medicine. 2005 Dec 1; 33(12):a159.
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    50. Roubinian N, Kirkpatrick BD, Lynn F, Zenilman J, Bash M. Neisseria meningitidis endotoxin and capsule transmission by transplantation. Emerg Infect Dis. 2005 Aug; 11(8):1326-7. PMID: 16110590.
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