Seth Shipman, PhD
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Title(s) | Assistant Professor, Bioengineering |
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School | School of Pharmacy |
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Address | 1650 Owens Street San Francisco CA 94158
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Phone | 415-734-4058 |
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vCard | Download vCard |
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Biography Wesleyan University, Connecticut | B.A. | 05/2005 | Neuroscience | University of California, San Francisco, San Francisco | Ph.D. | 12/2012 | Neuroscience | Harvard Medicall School, Boston | Postdoctoral Fellowship | 10/2018 | Genetics, Synthetic Biology, Stem Cell Biology |
Wesleyan University | 2001 | | Outstanding Physics Student Scholarship | National Science Foundation | 2007
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| 2008 | Graduate Research Fellowship, Honorable Mention | Grass Foundation | 2011 | | Grass Fellowship in Neuroscience (declined) | Earle C. Anthony | 2012 | | Travel Award | Gordon Research Conference | 2012 | | Poster Award | Life Science Research Foundation | 2014 | | Postdoctoral Award | DARPA | 2018 | | DARPA Riser, DARPA 60th Anniversity Symposium | Simonds Foundation Autism Research Initiative (SFARI) | 2019 | | Bridge to Indipendence Award | ScienceNews | 2019 | | The SN 10: Scientists to Watch |
Overview Dr. Seth Shipman's research focuses on cellular systems in the midst of change. His lab seeks to better understand how the order of transcriptional events during development can drive changes in cell fate, and to better intervene in diseases characterized by change, like progressive neurodegeneration and cancer. His lab takes a molecular engineering approach, leveraging the versatility of DNA as a programmable biological polymer to gather data without destroying cells, and deliver therapeutics that can modify their effect based on cell context.
Research ORNG Applications Bibliographic
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Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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A comprehensive library of human transcription factors for cell fate engineering. Nat Biotechnol. 2020 Nov 30.
Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM. PMID: 33257861.
View in: PubMed Mentions: Fields:
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Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration. Nat Microbiol. 2018 03; 3(3):310-318.
Nivala J, Shipman SL, Church GM. PMID: 29379209.
View in: PubMed Mentions: 5 Fields: Translation: Cells
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CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria. Nature. 2017 07 20; 547(7663):345-349.
Shipman SL, Nivala J, Macklis JD, Church GM. PMID: 28700573.
View in: PubMed Mentions: 27 Fields: Translation: Cells
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Molecular recordings by directed CRISPR spacer acquisition. Science. 2016 Jul 29; 353(6298):aaf1175.
Shipman SL, Nivala J, Macklis JD, Church GM. PMID: 27284167.
View in: PubMed Mentions: 26 Fields: Translation: Cells
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The cellular and molecular landscape of neuroligins. Trends Neurosci. 2015 Aug; 38(8):496-505.
Bemben MA, Shipman SL, Nicoll RA, Roche KW. PMID: 26209464.
View in: PubMed Mentions: 39 Fields: Translation: HumansAnimalsCells
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Rapid neurogenesis through transcriptional activation in human stem cells. Mol Syst Biol. 2014 Nov 17; 10:760.
Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM. PMID: 25403753.
View in: PubMed Mentions: 52 Fields: Translation: HumansCells
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CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses. Nat Neurosci. 2014 Jan; 17(1):56-64.
Bemben MA, Shipman SL, Hirai T, Herring BE, Li Y, Badger JD, Nicoll RA, Diamond JS, Roche KW. PMID: 24336150.
View in: PubMed Mentions: 32 Fields: Translation: HumansAnimalsCells
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Distance-dependent scaling of AMPARs is cell-autonomous and GluA2 dependent. J Neurosci. 2013 Aug 14; 33(33):13312-9.
Shipman SL, Herring BE, Suh YH, Roche KW, Nicoll RA. PMID: 23946389.
View in: PubMed Mentions: 11 Fields: Translation: HumansAnimalsCells
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Dimerization of postsynaptic neuroligin drives synaptic assembly via transsynaptic clustering of neurexin. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19432-7.
Shipman SL, Nicoll RA. PMID: 23129658.
View in: PubMed Mentions: 26 Fields: Translation: AnimalsCells
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A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP. Neuron. 2012 Oct 18; 76(2):309-16.
Shipman SL, Nicoll RA. PMID: 23083734.
View in: PubMed Mentions: 39 Fields: Translation: HumansAnimalsCells
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Functional dependence of neuroligin on a new non-PDZ intracellular domain. Nat Neurosci. 2011 Jun; 14(6):718-26.
Shipman SL, Schnell E, Hirai T, Chen BS, Roche KW, Nicoll RA. PMID: 21532576.
View in: PubMed Mentions: 49 Fields: Translation: AnimalsCells
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Absence of established sex differences in patients with schizophrenia on a two-dimensional object array task. Psychiatry Res. 2009 Apr 30; 166(2-3):158-65.
Shipman SL, Baker EK, Pearlson G, Astur RS. PMID: 19278735.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Factors affecting the hippocampal BOLD response during spatial memory. Behav Brain Res. 2008 Mar 05; 187(2):433-41.
Shipman SL, Astur RS. PMID: 18055028.
View in: PubMed Mentions: 25 Fields: Translation: Humans
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Year | Publications |
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2007 | 1 | 2009 | 1 | 2011 | 1 | 2012 | 2 | 2013 | 2 | 2014 | 1 | 2015 | 1 | 2016 | 1 | 2017 | 1 | 2018 | 1 | 2020 | 1 |
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