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SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS. Cell Stem Cell. 2023 Feb 02; 30(2):171-187.e14.
Linares GR, Li Y, Chang WH, Rubin-Sigler J, Mendonca S, Hong S, Eoh Y, Guo W, Huang YH, Chang J, Tu S, Dorjsuren N, Santana M, Hung ST, Yu J, Perez J, Chickering M, Cheng TY, Huang CC, Lee SJ, Deng HJ, Bach KT, Gray K, Subramanyam V, Rosenfeld J, Alworth SV, Goodarzi H, Ichida JK. PMID: 36736291.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance. Mol Cancer. 2023 Jan 21; 22(1):15.
Stejskal P, Goodarzi H, Srovnal J, Hajd?ch M, van 't Veer LJ, Magbanua MJM. PMID: 36681803; PMCID: PMC9862574.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Functional microRNA-Targeting Drug Discovery by Graph-Based Deep Learning. bioRxiv. 2023 Jan 16.
Arshadi AK, Salem M, Karner H, Garcia K, Arab A, Yuan JS, Goodarzi H. PMID: 36711761; PMCID: PMC9882104.
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PubMed Mentions:
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Two isoleucyl tRNAs that decode synonymous codons divergently regulate breast cancer metastatic growth by controlling translation of proliferation-regulating genes. Nat Cancer. 2022 12; 3(12):1484-1497.
Earnest-Noble LB, Hsu D, Chen S, Asgharian H, Nandan M, Passarelli MC, Goodarzi H, Tavazoie SF. PMID: 36510010.
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PubMed Mentions: Translation:
HumansAnimals
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95P Serum-based colorectal cancer detection using orphan noncoding RNAs. Annals of Oncology. 2022 Sep 1; 33:s582.
Goodarzi GH, Wang WJ, Afolabi AO, Fish FL, Li LH, Chau CK, Arensdorf AP, Hormozdiari HF, Alipanahi AB. .
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PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity. Sci Rep. 2022 07 16; 12(1):12186.
Furuya H, Sasaki Y, Chen R, Peres R, Hokutan K, Murakami K, Kim N, Chan OTM, Pagano I, Dyrskj?t L, Jensen JB, Malmstrom PU, Segersten U, Sun Y, Arab A, Goodarzi H, Goodison S, Rosser CJ. PMID: 35842542; PMCID: PMC9288475.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Postmortem Human Dura Mater Cells Exhibit Phenotypic, Transcriptomic and Genetic Abnormalities that Impact their Use for Disease Modeling. Stem Cell Rev Rep. 2022 12; 18(8):3050-3065.
Argouarch AR, Schultz N, Yang AC, Jang Y, Garcia K, Cosme CG, Corrales CI, Nana AL, Karydas AM, Spina S, Grinberg LT, Miller B, Wyss-Coray T, Abyzov A, Goodarzi H, Seeley WW, Kao AW. PMID: 35809166; PMCID: PMC9622518.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Abstract 3353: Discovery and validation of orphan noncoding RNA profiles across multiple cancers in TCGA and two independent cohorts. Cancer Research. 2022 Jun 15; 82(12_Supplement):3353-3353.
Wang WJ, Li LH, Fish FL, Chau CK, Arensdorf AP, Goodarzi GH, Alipanahi AB. .
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Identifying drivers of breast cancer metastasis in progressively invasive subpopulations of zebrafish-xenografted MDA-MB-231. Mol Biomed. 2022 May 26; 3(1):16.
Xiao J, McGill JR, Nasir A, Lekan A, Johnson B, Wilkins DJ, Pearson GW, Tanner K, Goodarzi H, Glasgow E, Schlegel R, Agarwal S. PMID: 35614362; PMCID: PMC9133282.
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PubMed Mentions:
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Leucyl-tRNA synthetase is a tumour suppressor in breast cancer and regulates codon-dependent translation dynamics. Nat Cell Biol. 2022 03; 24(3):307-315.
Passarelli MC, Pinzaru AM, Asgharian H, Liberti MV, Heissel S, Molina H, Goodarzi H, Tavazoie SF. PMID: 35288656; PMCID: PMC8977047.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Abstract PD9-04: Tumor-released circulating orphan non-coding RNAs reflect treatment response and survival in breast cancer. Cancer Research. 2022 Feb 15; 82(4_Supplement):pd9-04-pd9-04.
Goodarzi GH, Navickas NA, Wang WJ, Garcia GK, Magbanua MM, Fish FL, Swigart SL, Hirst HG, Wolf WD, Yau YC, Chien CJ, Simmons SC, Delson DA, Esserman EL, van 't Veer vL. .
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C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer. Nat Commun. 2022 01 10; 13(1):69.
Liu XZ, Rulina A, Choi MH, Pedersen L, Lepland J, Takle ST, Madeleine N, Peters SD, Wogsland CE, Gr?ndal SM, Lorens JB, Goodarzi H, L?nning PE, Knappskog S, Molven A, Halberg N. PMID: 35013251; PMCID: PMC8748947.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy. Genome Med. 2021 10 18; 13(1):167.
Yogodzinski C, Arab A, Pritchard JR, Goodarzi H, Gilbert LA. PMID: 34663427; PMCID: PMC8524992.
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PubMed Mentions: Fields:
Translation:
HumansCells
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ERa is an RNA-binding protein sustaining tumor cell survival and drug resistance. Cell. 2021 09 30; 184(20):5215-5229.e17.
Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D. PMID: 34559986; PMCID: PMC8547373.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells. Nat Commun. 2021 07 13; 12(1):4288.
Chen WC, To MD, Westcott PMK, Delrosario R, Kim IJ, Philips M, Tran Q, Bollam SR, Goodarzi H, Bayani N, Mirzoeva O, Balmain A. PMID: 34257283; PMCID: PMC8277813.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Rep. 2021 06 29; 35(13):109321.
Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D. PMID: 34192540; PMCID: PMC8323864.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA. Neuro-Oncology. 2021 Jun 1; 23(Suppl 1):i37-i37.
Schmidt SC, Navickas NA, Zindy ZF, Farmer FD, Ruggero RD, Goodarzi GH, Roussel RM, Schwer SB, Weiss WW. .
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A Wnt twist in FTO's role in cancer progression. Nat Cancer. 2021 06; 2(6):579-580.
Navickas A, Goodarzi H. PMID: 35121942.
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PubMed Mentions: Translation:
Humans
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A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements. Science. 2021 05 14; 372(6543).
Fish L, Khoroshkin M, Navickas A, Garcia K, Culbertson B, H?nisch B, Zhang S, Nguyen HCB, Soto LM, Dermit M, Mardakheh FK, Molina H, Alarc?n C, Najafabadi HS, Goodarzi H. PMID: 33986153; PMCID: PMC8238114.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Neuronal Nsun2 Deficiency is Associated With Codon-Specific Epitranscriptomic Dysregulation of Gly-Trnas and Corresponding Proteomic Shift Impacting Synaptic Signaling and Behavior. Biological Psychiatry. 2021 May 1; 89(9):s207-s208.
Blaze BJ, Phillips PH, Heissel HS, Navickas NA, Plaza-Jennings PA, Foo FM, Katanski KC, Watkins WC, Pennington PZ, Javidfar JB, Espeso-Gil ES, Molina MH, Cai CD, Pan PT, Yao YW, Goodarzi GH, Haghighi HF, Akbarian AS. .
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Abstract PS19-01: A sense-antisense RNA interaction drives metabolic reprogramming in metastatic breast cancer. Cancer Research. 2021 Feb 15; 81(4_Supplement):ps19-01-ps19-01.
Goodarzi GH, Culbertson CB, Garcia GK, Fish FL. .
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A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression. EMBO J. 2021 01 15; 40(2):e106696.
Huh D, Passarelli MC, Gao J, Dusmatova SN, Goin C, Fish L, Pinzaru AM, Molina H, Ren Z, McMillan EA, Asgharian H, Goodarzi H, Tavazoie SF. PMID: 33346941; PMCID: PMC7809793.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Massively multiplex single-molecule oligonucleosome footprinting. Elife. 2020 12 02; 9.
Abdulhay NJ, McNally CP, Hsieh LJ, Kasinathan S, Keith A, Estes LS, Karimzadeh M, Underwood JG, Goodarzi H, Narlikar GJ, Ramani V. PMID: 33263279; PMCID: PMC7735760.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell. 2020 12 03; 27(6):876-889.e12.
Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F. PMID: 33232663; PMCID: PMC7670929.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Functional Genomics In�Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells. Cell Metab. 2021 01 05; 33(1):211-221.e6.
Zhu XG, Chudnovskiy A, Baudrier L, Prizer B, Liu Y, Ostendorf BN, Yamaguchi N, Arab A, Tavora B, Timson R, Heissel S, de Stanchina E, Molina H, Victora GD, Goodarzi H, Birsoy K. PMID: 33152324; PMCID: PMC7790894.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis. Nature. 2020 10; 586(7828):299-304.
Tavora B, Mederer T, Wessel KJ, Ruffing S, Sadjadi M, Missmahl M, Ostendorf BN, Liu X, Kim JY, Olsen O, Welm AL, Goodarzi H, Tavazoie SF. PMID: 32999457; PMCID: PMC8088828.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development. Front Artif Intell. 2020; 3:65.
Keshavarzi Arshadi A, Webb J, Salem M, Cruz E, Calad-Thomson S, Ghadirian N, Collins J, Diez-Cecilia E, Kelly B, Goodarzi H, Yuan JS. PMID: 33733182; PMCID: PMC7861281.
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PubMed Mentions:
51
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The DNA methylation landscape of advanced prostate cancer. Nat Genet. 2020 08; 52(8):778-789.
Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sj?str?m M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, Chow ED, Perry MD, Dang HX, Yang R, Moussavi-Baygi R, Zhang L, Alshalalfa M, Laura Chang S, Houlahan KE, Shiah YJ, Beer TM, Thomas G, Chi KN, Gleave M, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Yvonne Kim M, Fong L, Spratt DE, Morgan TM, Bose R, Huang FW, Li H, Chesner L, Shenoy T, Goodarzi H, Asangani IA, Sandhu S, Lang JM, Mahajan NP, Lara PN, Evans CP, Febbo P, Batzoglou S, Knudsen KE, He HH, Huang J, Zwart W, Costello JF, Luo J, Tomlins SA, Wyatt AW, Dehm SM, Ashworth A, Gilbert LA, Boutros PC, Farh K, Chinnaiyan AM, Maher CA, Small EJ, Quigley DA, Feng FY. PMID: 32661416; PMCID: PMC7454228.
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PubMed Mentions:
87 Fields:
Translation:
HumansCells
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RBMS1 Suppresses Colon Cancer Metastasis through Targeted Stabilization of Its mRNA Regulon. Cancer Discov. 2020 09; 10(9):1410-1423.
Yu J, Navickas A, Asgharian H, Culbertson B, Fish L, Garcia K, Olegario JP, Dermit M, Dodel M, H?nisch B, Luo Y, Weinberg EM, Dienstmann R, Warren RS, Mardakheh FK, Goodarzi H. PMID: 32513775; PMCID: PMC7483797.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Androgen Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. bioRxiv. 2020 May 15.
Ghazizadeh Z, Majd H, Richter M, Samuel R, Zekavat SM, Asgharian H, Farahvashi S, Kalantari A, Ramirez J, Zhao H, Natarajan P, Goodarzi H, Fattahi F. PMID: 32511360; PMCID: PMC7263488.
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PubMed Mentions:
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Abstract PD8-07: A pro-metastatic alternative splicing program that drives breast cancer progression. Cancer Research. 2020 Feb 15; 80(4_Supplement):pd8-07-pd8-07.
Goodarzi GH, Fish FL, Culbertson CB. .
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The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat Cell Biol. 2020 02; 22(2):187-199.
Leidal AM, Huang HH, Marsh T, Solvik T, Zhang D, Ye J, Kai F, Goldsmith J, Liu JY, Huang YH, Monkkonen T, Vlahakis A, Huang EJ, Goodarzi H, Yu L, Wiita AP, Debnath J. PMID: 31932738; PMCID: PMC7007875.
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PubMed Mentions:
148 Fields:
Translation:
HumansAnimalsCells
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PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis. Elife. 2019 12 16; 8.
Yamaguchi N, Weinberg EM, Nguyen A, Liberti MV, Goodarzi H, Janjigian YY, Paty PB, Saltz LB, Kingham TP, Loo JM, de Stanchina E, Tavazoie SF. PMID: 31841108; PMCID: PMC7299340.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
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Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Mol Cell. 2019 09 05; 75(5):967-981.e9.
Fish L, Navickas A, Culbertson B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Alarcón C, Ruggero D, Goodarzi H. PMID: 31300274; PMCID: PMC6731133.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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A massively parallel 3' UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization. Genome Res. 2019 06; 29(6):896-906.
Litterman AJ, Kageyama R, Le Tonqueze O, Zhao W, Gagnon JD, Goodarzi H, Erle DJ, Ansel KM. PMID: 31152051; PMCID: PMC6581050.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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A regulatory program that promotes metastasis in colorectal cancer (CRC) through modulation of mRNA stability. Journal of Clinical Oncology. 2019 May 20; 37(15_suppl):3523-3523.
Goodarzi GH, Warren WR, Yu YJ, Fish FL. .
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FTO controls reversible m6Am RNA methylation during snRNA biogenesis. Nat Chem Biol. 2019 04; 15(4):340-347.
Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur JJ, Rentmeister A, Gross SS, Pellizzoni L, Debart F, Goodarzi H, Jaffrey SR. PMID: 30778204; PMCID: PMC6984009.
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PubMed Mentions:
100 Fields:
Translation:
HumansAnimalsCells
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Cancer cells exploit an orphan RNA to drive metastatic progression. Nat Med. 2018 11; 24(11):1743-1751.
Fish L, Zhang S, Yu JX, Culbertson B, Zhou AY, Goga A, Goodarzi H. PMID: 30397354; PMCID: PMC6223318.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Publisher Correction: Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer's disease. Nat Commun. 2018 10 31; 9(1):4625.
Alkallas R, Fish L, Goodarzi H, Najafabadi HS. PMID: 30382106; PMCID: PMC6208437.
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PubMed Mentions:
1 Fields:
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Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell. 2018 10 18; 175(3):889.
Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY. PMID: 30340047.
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PubMed Mentions:
52 Fields:
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Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell. 2018 07 26; 174(3):758-769.e9.
Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY. PMID: 30033370; PMCID: PMC6425931.
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PubMed Mentions:
211 Fields:
Translation:
HumansCells
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Erratum: Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. 2018 04 04; 556(7699):135.
Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. PMID: 29620732.
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PubMed Mentions:
5 Fields:
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Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. 2018 02 15; 554(7692):378-381.
Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. PMID: 29414946; PMCID: PMC5898613.
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PubMed Mentions:
190 Fields:
Translation:
HumansAnimalsCells
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Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer's disease. Nat Commun. 2017 10 13; 8(1):909.
Alkallas R, Fish L, Goodarzi H, Najafabadi HS. PMID: 29030541; PMCID: PMC5714957.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interface. PeerJ. 2017; 5:e3685.
Bukowski R, Sadovsky Y, Goodarzi H, Zhang H, Biggio JR, Varner M, Parry S, Xiao F, Esplin SM, Andrews W, Saade GR, Ilekis JV, Reddy UM, Baldwin DA. PMID: 28879060; PMCID: PMC5582610.
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PubMed Mentions:
37
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Charting the "unknown unknowns" of cancer progression. Sci Transl Med. 2017 07 26; 9(400).
Goodarzi H. PMID: 28747512.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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MicroRNA-203 predicts human survival after resection of colorectal liver metastasis. Oncotarget. 2017 Mar 21; 8(12):18821-18831.
Kingham TP, Nguyen HCB, Zheng J, Konstantinidis IT, Sadot E, Shia J, Kuk D, Zhang S, Saltz L, D'Angelica MI, Jarnagin WR, Goodarzi H, Tavazoie SF. PMID: 27935861; PMCID: PMC5386650.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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TMEM2 Is a SOX4-Regulated Gene That Mediates Metastatic Migration and Invasion in Breast Cancer. Cancer Res. 2016 09 01; 76(17):4994-5005.
Lee H, Goodarzi H, Tavazoie SF, Alarcón CR. PMID: 27328729; PMCID: PMC5110434.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression. Cell. 2016 Jun 02; 165(6):1416-1427.
Goodarzi H, Nguyen HCB, Zhang S, Dill BD, Molina H, Tavazoie SF. PMID: 27259150; PMCID: PMC4915377.
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PubMed Mentions:
204 Fields:
Translation:
HumansAnimalsCells
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Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nat Commun. 2016 May 03; 7:11246.
Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF. PMID: 27138336; PMCID: PMC4857405.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. Cell Rep. 2016 Apr 12; 15(2):423-35.
Hwang HW, Park CY, Goodarzi H, Fak JJ, Mele A, Moore MJ, Saito Y, Darnell RB. PMID: 27050522; PMCID: PMC4832608.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts. Genes Dev. 2016 Feb 15; 30(4):386-98.
Fish L, Pencheva N, Goodarzi H, Tran H, Yoshida M, Tavazoie SF. PMID: 26883358; PMCID: PMC4762424.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events. Cell. 2015 Sep 10; 162(6):1299-308.
Alarc?n CR, Goodarzi H, Lee H, Liu X, Tavazoie S, Tavazoie SF. PMID: 26321680; PMCID: PMC4673968.
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PubMed Mentions:
595 Fields:
Translation:
HumansCells
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Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival. Nat Cell Biol. 2015 Jul; 17(7):943-52.
Furlow PW, Zhang S, Soong TD, Halberg N, Goodarzi H, Mangrum C, Wu YG, Elemento O, Tavazoie SF. PMID: 26098574; PMCID: PMC5310712.
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PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
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Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement. Cell. 2015 May 07; 161(4):790-802.
Goodarzi H, Liu X, Nguyen HC, Zhang S, Fish L, Tavazoie SF. PMID: 25957686; PMCID: PMC4457382.
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PubMed Mentions:
373 Fields:
Translation:
HumansCells
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N6-methyladenosine marks primary microRNAs for processing. Nature. 2015 Mar 26; 519(7544):482-5.
Alarc?n CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF. PMID: 25799998; PMCID: PMC4475635.
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PubMed Mentions:
569 Fields:
Translation:
HumansCells
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Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins. Nature. 2014 Sep 11; 513(7517):256-60.
Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF. PMID: 25043050; PMCID: PMC4440807.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Systematic identification of regulatory elements in conserved 3' UTRs of human transcripts. Cell Rep. 2014 Apr 10; 7(1):281-92.
Oikonomou P, Goodarzi H, Tavazoie S. PMID: 24656821; PMCID: PMC4430845.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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TARBP2 binding structured RNA elements drives metastasis. Cell Cycle. 2014; 13(18):2799-800.
Goodarzi H, Tavazoie SF, Tavazoie S. PMID: 25486461; PMCID: PMC4612561.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Revealing the genetic basis of natural bacterial phenotypic divergence. J Bacteriol. 2014 Feb; 196(4):825-39.
Freddolino PL, Goodarzi H, Tavazoie S. PMID: 24317396; PMCID: PMC3911184.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Rep. 2013 Jul 25; 4(2):385-401.
Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S, Myers RM, Maniatis T. PMID: 23850290; PMCID: PMC4272581.
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PubMed Mentions:
327 Fields:
Translation:
HumansAnimalsCells
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Fitness landscape transformation through a single amino acid change in the rho terminator. PLoS Genet. 2012 May; 8(5):e1002744.
Freddolino PL, Goodarzi H, Tavazoie S. PMID: 22693458; PMCID: PMC3364947.
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PubMed Mentions:
25 Fields:
Translation:
Cells
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Systematic discovery of structural elements governing stability of mammalian messenger RNAs. Nature. 2012 Apr 08; 485(7397):264-8.
Goodarzi H, Najafabadi HS, Oikonomou P, Greco TM, Fish L, Salavati R, Cristea IM, Tavazoie S. PMID: 22495308; PMCID: PMC3350620.
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PubMed Mentions:
90 Fields:
Translation:
HumansAnimalsCells
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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med. 2011 Aug 07; 17(9):1101-8.
Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celi?-Terrassa T, Mercatali L, Khan Z, Goodarzi H, Hua Y, Wei Y, Hu G, Garcia BA, Ragoussis J, Amadori D, Harris AL, Kang Y. PMID: 21822286; PMCID: PMC3169707.
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PubMed Mentions:
337 Fields:
Translation:
HumansAnimalsCells
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Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Mol Syst Biol. 2010 Jun 08; 6:378.
Goodarzi H, Bennett BD, Amini S, Reaves ML, Hottes AK, Rabinowitz JD, Tavazoie S. PMID: 20531407; PMCID: PMC2913397.
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PubMed Mentions:
75 Fields:
Translation:
Cells
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Revealing global regulatory perturbations across human cancers. Mol Cell. 2009 Dec 11; 36(5):900-11.
Goodarzi H, Elemento O, Tavazoie S. PMID: 20005852; PMCID: PMC2900319.
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PubMed Mentions:
120 Fields:
Translation:
Humans
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Universal function-specificity of codon usage. Nucleic Acids Res. 2009 Nov; 37(21):7014-23.
Najafabadi HS, Goodarzi H, Salavati R. PMID: 19773421; PMCID: PMC2790905.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Global discovery of adaptive mutations. Nat Methods. 2009 Aug; 6(8):581-3.
Goodarzi H, Hottes AK, Tavazoie S. PMID: 19597501; PMCID: PMC2762608.
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PubMed Mentions:
19 Fields:
Translation:
Cells
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Genetic dissection of an exogenously induced biofilm in laboratory and clinical isolates of E. coli. PLoS Pathog. 2009 May; 5(5):e1000432.
Amini S, Goodarzi H, Tavazoie S. PMID: 19436718; PMCID: PMC2675270.
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PubMed Mentions:
24 Fields:
Translation:
Cells
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Amino acid and codon usage profiles: adaptive changes in the frequency of amino acids and codons. Gene. 2008 Jan 15; 407(1-2):30-41.
Goodarzi H, Torabi N, Najafabadi HS, Archetti M. PMID: 17977670.
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PubMed Mentions:
27 Fields:
Translation:
Cells
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Intragenic SNP haplotypes associated with 84dup18 mutation in TNFRSF11A in four FEO pedigrees suggest three independent origins for this mutation. J Bone Miner Metab. 2007; 25(3):159-64.
Elahi E, Shafaghati Y, Asadi S, Absalan F, Goodarzi H, Gharaii N, Karimi-Nejad MH, Shahram F, Hughes AE. PMID: 17447113.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Solvent accessibility, residue charge and residue volume, the three ingredients of a robust amino acid substitution matrix. J Theor Biol. 2007 Apr 21; 245(4):715-25.
Goodarzi H, Katanforoush A, Torabi N, Najafabadi HS. PMID: 17240399.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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The case for an error minimizing set of coding amino acids. J Theor Biol. 2007 Feb 21; 244(4):737-44.
Torabi N, Goodarzi H, Shateri Najafabadi H. PMID: 17069856.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Importance of RNA secondary structure information for yeast donor and acceptor splice site predictions by neural networks. Comput Biol Chem. 2006 Feb; 30(1):50-7.
Marashi SA, Goodarzi H, Sadeghi M, Eslahchi C, Pezeshk H. PMID: 16386465.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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The impact of including tRNA content on the optimality of the genetic code. Bull Math Biol. 2005 Nov; 67(6):1355-68.
Goodarzi H, Najafabadi HS, Nejad HA, Torabi N. PMID: 16005951.
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PubMed Mentions:
5 Fields:
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On the coevolution of genes and genetic code. Gene. 2005 Dec 05; 362:133-40.
Goodarzi H, Shateri Najafabadi H, Torabi N. PMID: 16213111.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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On the optimality of the genetic code, with the consideration of coevolution theory by comparison of prominent cost measure matrices. J Theor Biol. 2005 Aug 07; 235(3):318-25.
Goodarzi H, Najafabadi HS, Hassani K, Nejad HA, Torabi N. PMID: 15882694.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Applying a neural network to predict the thermodynamic parameters for an expanded nearest-neighbor model. J Theor Biol. 2006 Feb 07; 238(3):657-65.
Najafabadi HS, Goodarzi H, Torabi N, Banihosseini SS. PMID: 16061260.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Designing a neural network for the constraint optimization of the fitness functions devised based on the load minimization of the genetic code. Biosystems. 2005 Aug; 81(2):91-100.
Goodarzi H, Najafabadi HS, Torabi N. PMID: 15936137.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Optimality of codon usage in Escherichia coli due to load minimization. J Theor Biol. 2005 Nov 21; 237(2):203-9.
Najafabadi HS, Goodarzi H, Torabi N. PMID: 15932760.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Correspondence regarding Bharanidharan et al., "Correlations between nucleotide frequencies and amino acid composition in 115 bacterial species". Biochem Biophys Res Commun. 2004 Dec 03; 325(1):1-2.
Najafabadi HS, Goodarzi H. PMID: 15522192.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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On the optimality of the genetic code, with the consideration of termination codons. Biosystems. 2004 Nov; 77(1-3):163-73.
Goodarzi H, Nejad HA, Torabi N. PMID: 15527955.
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PubMed Mentions:
18 Fields:
Translation:
Cells