Hani Goodarzi, PhD

Title(s)Assistant Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St
San Francisco CA 94158
Phone415-230-5189
ORCID ORCID Icon0000-0002-9648-8949 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Rockefeller University, New YorkPostdoctoral04/2016Cancer Systems Biology
    Princeton, New JerseyPhD10/2010Computational Biology & Genomics
    Collapse Awards and Honors
    2017AAAS Martin and Rose Wachtel Cancer Research Award
    2017AACR NextGen Award for Transformative Cancer Research
    2017Sidney Kimmel Cancer Foundation Scholar Award
    2015Blavatnik Regional Awards for Young Scientists
    2015Tri-Institutional Breakout Prize for Junior Investigators

    Collapse Overview 
    Collapse Overview
    Cancer, fundamentally, is a disease of disordered gene expression. Cancer cells rely on deregulated expression of oncogenic and tumor suppressive pathways to initiate and maintain the transformation process. Thus, delineating how cancer cells achieve such pathologic gene expression states is a crucial step towards understanding and ultimately treating cancer as a disease. Towards achieving this goal, my laboratory employs a systems biological and multidisciplinary approach that integrates computational and experimental strategies to identify and characterize key regulatory programs that underlie cancer progression. The systems-level frameworks implemented in our lab ensure a truly unbiased and systematic approach to studying this key biological challenge. Such bottom-up and agnostic approaches are crucial for discovering pathways that fall outside of our prior knowledge of regulatory interactions and would otherwise remain hidden in a top-down reductionist framework.
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    The RNA structural code underlying pathological regulation of RNA splicing in metastasis
    NIH R01CA244634Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    An antisense RNA-mediated regulatory program that drives cancer metastasis
    NIH R01CA240984Jul 1, 2019 - Jun 30, 2024
    Role: Principal Investigator
    Targeted regulation of transcript stability through RNA methylation and intron retention
    NIH R01GM123977Sep 1, 2017 - Aug 31, 2022
    Role: Principal Investigator
    Systematic dissection of an aberrant splicing program driving cancer metastasis
    NIH R00CA194077May 1, 2016 - Apr 30, 2020
    Role: Principal Investigator
    Structural RNA elements and their roles in post-transcriptional regulation
    NIH K99CA194077Jul 21, 2015 - Apr 30, 2016
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance. Cell. 2021 Sep 30; 184(20):5215-5229.e17. Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D. PMID: 34559986.
      View in: PubMed   Mentions:    Fields:    
    2. Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells. Nat Commun. 2021 07 13; 12(1):4288. Chen WC, To MD, Westcott PMK, Delrosario R, Kim IJ, Philips M, Tran Q, Bollam SR, Goodarzi H, Bayani N, Mirzoeva O, Balmain A. PMID: 34257283.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Rep. 2021 Jun 29; 35(13):109321. Kuzuoglu-Ozturk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang GG, Worland ST, Brenner SE, Goodarzi H, Gilbert LA, Ruggero D. PMID: 34192540.
      View in: PubMed   Mentions:    Fields:    
    4. A Wnt twist in FTO’s role in cancer progression. Nature Cancer. 2021 Jun 23; 2(6):579-580. Navickas NA, Goodarzi GH. .
      View in: Publisher Site   Mentions:
    5. OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA. Neuro-Oncology. 2021 Jun 1; 23(Suppl 1):i37-i37. Schmidt SC, Navickas NA, Zindy ZF, Farmer FD, Ruggero RD, Goodarzi GH, Roussel RM, Schwer SB, Weiss WW. .
      View in: Publisher Site   Mentions:
    6. A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements. Science. 2021 05 14; 372(6543). Fish L, Khoroshkin M, Navickas A, Garcia K, Culbertson B, Hänisch B, Zhang S, Nguyen HCB, Soto LM, Dermit M, Mardakheh FK, Molina H, Alarcón C, Najafabadi HS, Goodarzi H. PMID: 33986153.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Neuronal Nsun2 Deficiency is Associated With Codon-Specific Epitranscriptomic Dysregulation of Gly-Trnas and Corresponding Proteomic Shift Impacting Synaptic Signaling and Behavior. Biological Psychiatry. 2021 May 1; 89(9):s207-s208. Blaze BJ, Phillips PH, Heissel HS, Navickas NA, Plaza-Jennings PA, Foo FM, Katanski KC, Watkins WC, Pennington PZ, Javidfar JB, Espeso-Gil ES, Molina MH, Cai CD, Pan PT, Yao YW, Goodarzi GH, Haghighi HF, Akbarian AS. .
      View in: Publisher Site   Mentions:
    8. A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression. EMBO J. 2021 01 15; 40(2):e106696. Huh D, Passarelli MC, Gao J, Dusmatova SN, Goin C, Fish L, Pinzaru AM, Molina H, Ren Z, McMillan EA, Asgharian H, Goodarzi H, Tavazoie SF. PMID: 33346941.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    9. Massively multiplex single-molecule oligonucleosome footprinting. Elife. 2020 12 02; 9. Abdulhay NJ, McNally CP, Hsieh LJ, Kasinathan S, Keith A, Estes LS, Karimzadeh M, Underwood JG, Goodarzi H, Narlikar GJ, Ramani V. PMID: 33263279.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    10. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell. 2020 12 03; 27(6):876-889.e12. Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F. PMID: 33232663.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    11. Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells. Cell Metab. 2021 01 05; 33(1):211-221.e6. Zhu XG, Chudnovskiy A, Baudrier L, Prizer B, Liu Y, Ostendorf BN, Yamaguchi N, Arab A, Tavora B, Timson R, Heissel S, de Stanchina E, Molina H, Victora GD, Goodarzi H, Birsoy K. PMID: 33152324.
      View in: PubMed   Mentions: 7     Fields:    
    12. Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis. Nature. 2020 10; 586(7828):299-304. Tavora B, Mederer T, Wessel KJ, Ruffing S, Sadjadi M, Missmahl M, Ostendorf BN, Liu X, Kim JY, Olsen O, Welm AL, Goodarzi H, Tavazoie SF. PMID: 32999457.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    13. Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development. Front Artif Intell. 2020; 3:65. Keshavarzi Arshadi A, Webb J, Salem M, Cruz E, Calad-Thomson S, Ghadirian N, Collins J, Diez-Cecilia E, Kelly B, Goodarzi H, Yuan JS. PMID: 33733182.
      View in: PubMed   Mentions:
    14. The DNA methylation landscape of advanced prostate cancer. Nat Genet. 2020 08; 52(8):778-789. Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sjöström M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, Chow ED, Perry MD, Dang HX, Yang R, Moussavi-Baygi R, Zhang L, Alshalalfa M, Laura Chang S, Houlahan KE, Shiah YJ, Beer TM, Thomas G, Chi KN, Gleave M, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Yvonne Kim M, Fong L, Spratt DE, Morgan TM, Bose R, Huang FW, Li H, Chesner L, Shenoy T, Goodarzi H, Asangani IA, Sandhu S, Lang JM, Mahajan NP, Lara PN, Evans CP, Febbo P, Batzoglou S, Knudsen KE, He HH, Huang J, Zwart W, Costello JF, Luo J, Tomlins SA, Wyatt AW, Dehm SM, Ashworth A, Gilbert LA, Boutros PC, Farh K, Chinnaiyan AM, Maher CA, Small EJ, Quigley DA, Feng FY. PMID: 32661416.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    15. RBMS1 Suppresses Colon Cancer Metastasis through Targeted Stabilization of Its mRNA Regulon. Cancer Discov. 2020 09; 10(9):1410-1423. Yu J, Navickas A, Asgharian H, Culbertson B, Fish L, Garcia K, Olegario JP, Dermit M, Dodel M, Hänisch B, Luo Y, Weinberg EM, Dienstmann R, Warren RS, Mardakheh FK, Goodarzi H. PMID: 32513775.
      View in: PubMed   Mentions: 2     Fields:    
    16. Androgen Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. bioRxiv. 2020 May 15. Ghazizadeh Z, Majd H, Richter M, Samuel R, Zekavat SM, Asgharian H, Farahvashi S, Kalantari A, Ramirez J, Zhao H, Natarajan P, Goodarzi H, Fattahi F. PMID: 32511360.
      View in: PubMed   Mentions:
    17. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat Cell Biol. 2020 02; 22(2):187-199. Leidal AM, Huang HH, Marsh T, Solvik T, Zhang D, Ye J, Kai F, Goldsmith J, Liu JY, Huang YH, Monkkonen T, Vlahakis A, Huang EJ, Goodarzi H, Yu L, Wiita AP, Debnath J. PMID: 31932738.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    18. PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis. Elife. 2019 12 16; 8. Yamaguchi N, Weinberg EM, Nguyen A, Liberti MV, Goodarzi H, Janjigian YY, Paty PB, Saltz LB, Kingham TP, Loo JM, de Stanchina E, Tavazoie SF. PMID: 31841108.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    19. Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Mol Cell. 2019 09 05; 75(5):967-981.e9. Fish L, Navickas A, Culbertson B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Alarcón C, Ruggero D, Goodarzi H. PMID: 31300274.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    20. A massively parallel 3' UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization. Genome Res. 2019 06; 29(6):896-906. Litterman AJ, Kageyama R, Le Tonqueze O, Zhao W, Gagnon JD, Goodarzi H, Erle DJ, Ansel KM. PMID: 31152051.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    21. A regulatory program that promotes metastasis in colorectal cancer (CRC) through modulation of mRNA stability. Journal of Clinical Oncology. 2019 May 20; 37(15_suppl):3523-3523. Goodarzi GH, Warren WR, Yu YJ, Fish FL. .
      View in: Publisher Site   Mentions:
    22. FTO controls reversible m6Am RNA methylation during snRNA biogenesis. Nat Chem Biol. 2019 04; 15(4):340-347. Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur JJ, Rentmeister A, Gross SS, Pellizzoni L, Debart F, Goodarzi H, Jaffrey SR. PMID: 30778204.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    23. Cancer cells exploit an orphan RNA to drive metastatic progression. Nat Med. 2018 11; 24(11):1743-1751. Fish L, Zhang S, Yu JX, Culbertson B, Zhou AY, Goga A, Goodarzi H. PMID: 30397354.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    24. Publisher Correction: Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer's disease. Nat Commun. 2018 10 31; 9(1):4625. Alkallas R, Fish L, Goodarzi H, Najafabadi HS. PMID: 30382106.
      View in: PubMed   Mentions: 1     Fields:    
    25. Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell. 2018 10 18; 175(3):889. Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY. PMID: 30340047.
      View in: PubMed   Mentions: 30     Fields:    
    26. Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell. 2018 07 26; 174(3):758-769.e9. Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY. PMID: 30033370.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    27. Erratum: Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. 2018 04 04; 556(7699):135. Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. PMID: 29620732.
      View in: PubMed   Mentions: 4     Fields:    
    28. Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. 2018 02 15; 554(7692):378-381. Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. PMID: 29414946.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    29. Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer's disease. Nat Commun. 2017 10 13; 8(1):909. Alkallas R, Fish L, Goodarzi H, Najafabadi HS. PMID: 29030541.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    30. Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interface. PeerJ. 2017; 5:e3685. Bukowski R, Sadovsky Y, Goodarzi H, Zhang H, Biggio JR, Varner M, Parry S, Xiao F, Esplin SM, Andrews W, Saade GR, Ilekis JV, Reddy UM, Baldwin DA. PMID: 28879060.
      View in: PubMed   Mentions:
    31. Charting the "unknown unknowns" of cancer progression. Sci Transl Med. 2017 07 26; 9(400). Goodarzi H. PMID: 28747512.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    32. MicroRNA-203 predicts human survival after resection of colorectal liver metastasis. Oncotarget. 2017 Mar 21; 8(12):18821-18831. Kingham TP, Nguyen HCB, Zheng J, Konstantinidis IT, Sadot E, Shia J, Kuk D, Zhang S, Saltz L, D'Angelica MI, Jarnagin WR, Goodarzi H, Tavazoie SF. PMID: 27935861.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. TMEM2 Is a SOX4-Regulated Gene That Mediates Metastatic Migration and Invasion in Breast Cancer. Cancer Res. 2016 09 01; 76(17):4994-5005. Lee H, Goodarzi H, Tavazoie SF, Alarcón CR. PMID: 27328729.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    34. Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression. Cell. 2016 Jun 02; 165(6):1416-1427. Goodarzi H, Nguyen HCB, Zhang S, Dill BD, Molina H, Tavazoie SF. PMID: 27259150.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    35. Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nat Commun. 2016 May 03; 7:11246. Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF. PMID: 27138336.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    36. PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. Cell Rep. 2016 Apr 12; 15(2):423-35. Hwang HW, Park CY, Goodarzi H, Fak JJ, Mele A, Moore MJ, Saito Y, Darnell RB. PMID: 27050522.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    37. Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts. Genes Dev. 2016 Feb 15; 30(4):386-98. Fish L, Pencheva N, Goodarzi H, Tran H, Yoshida M, Tavazoie SF. PMID: 26883358.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    38. HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events. Cell. 2015 Sep 10; 162(6):1299-308. Alarcón CR, Goodarzi H, Lee H, Liu X, Tavazoie S, Tavazoie SF. PMID: 26321680.
      View in: PubMed   Mentions: 375     Fields:    Translation:HumansCells
    39. Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival. Nat Cell Biol. 2015 Jul; 17(7):943-52. Furlow PW, Zhang S, Soong TD, Halberg N, Goodarzi H, Mangrum C, Wu YG, Elemento O, Tavazoie SF. PMID: 26098574.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    40. Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement. Cell. 2015 May 07; 161(4):790-802. Goodarzi H, Liu X, Nguyen HC, Zhang S, Fish L, Tavazoie SF. PMID: 25957686.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansCells
    41. N6-methyladenosine marks primary microRNAs for processing. Nature. 2015 Mar 26; 519(7544):482-5. Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF. PMID: 25799998.
      View in: PubMed   Mentions: 377     Fields:    Translation:HumansCells
    42. Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins. Nature. 2014 Sep 11; 513(7517):256-60. Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF. PMID: 25043050.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    43. Systematic identification of regulatory elements in conserved 3' UTRs of human transcripts. Cell Rep. 2014 Apr 10; 7(1):281-92. Oikonomou P, Goodarzi H, Tavazoie S. PMID: 24656821.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    44. TARBP2 binding structured RNA elements drives metastasis. . 2014; 13(18):2799-800. Goodarzi H, Tavazoie SF, Tavazoie S. PMID: 25486461.
      View in: PubMed   Mentions:
    45. Revealing the genetic basis of natural bacterial phenotypic divergence. J Bacteriol. 2014 Feb; 196(4):825-39. Freddolino PL, Goodarzi H, Tavazoie S. PMID: 24317396.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    46. A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Rep. 2013 Jul 25; 4(2):385-401. Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S, Myers RM, Maniatis T. PMID: 23850290.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansAnimalsCells
    47. Fitness landscape transformation through a single amino acid change in the rho terminator. PLoS Genet. 2012 May; 8(5):e1002744. Freddolino PL, Goodarzi H, Tavazoie S. PMID: 22693458.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    48. Systematic discovery of structural elements governing stability of mammalian messenger RNAs. Nature. 2012 Apr 08; 485(7397):264-8. Goodarzi H, Najafabadi HS, Oikonomou P, Greco TM, Fish L, Salavati R, Cristea IM, Tavazoie S. PMID: 22495308.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    49. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med. 2011 Aug 07; 17(9):1101-8. Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celià-Terrassa T, Mercatali L, Khan Z, Goodarzi H, Hua Y, Wei Y, Hu G, Garcia BA, Ragoussis J, Amadori D, Harris AL, Kang Y. PMID: 21822286.
      View in: PubMed   Mentions: 302     Fields:    Translation:HumansAnimalsCells
    50. Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Mol Syst Biol. 2010 Jun 08; 6:378. Goodarzi H, Bennett BD, Amini S, Reaves ML, Hottes AK, Rabinowitz JD, Tavazoie S. PMID: 20531407.
      View in: PubMed   Mentions: 67     Fields:    Translation:Cells
    51. Revealing global regulatory perturbations across human cancers. Mol Cell. 2009 Dec 11; 36(5):900-11. Goodarzi H, Elemento O, Tavazoie S. PMID: 20005852.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    52. Universal function-specificity of codon usage. Nucleic Acids Res. 2009 Nov; 37(21):7014-23. Najafabadi HS, Goodarzi H, Salavati R. PMID: 19773421.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    53. Global discovery of adaptive mutations. Nat Methods. 2009 Aug; 6(8):581-3. Goodarzi H, Hottes AK, Tavazoie S. PMID: 19597501.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    54. Genetic dissection of an exogenously induced biofilm in laboratory and clinical isolates of E. coli. PLoS Pathog. 2009 May; 5(5):e1000432. Amini S, Goodarzi H, Tavazoie S. PMID: 19436718.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    55. Amino acid and codon usage profiles: adaptive changes in the frequency of amino acids and codons. Gene. 2008 Jan 15; 407(1-2):30-41. Goodarzi H, Torabi N, Najafabadi HS, Archetti M. PMID: 17977670.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    56. Intragenic SNP haplotypes associated with 84dup18 mutation in TNFRSF11A in four FEO pedigrees suggest three independent origins for this mutation. J Bone Miner Metab. 2007; 25(3):159-64. Elahi E, Shafaghati Y, Asadi S, Absalan F, Goodarzi H, Gharaii N, Karimi-Nejad MH, Shahram F, Hughes AE. PMID: 17447113.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    57. Solvent accessibility, residue charge and residue volume, the three ingredients of a robust amino acid substitution matrix. J Theor Biol. 2007 Apr 21; 245(4):715-25. Goodarzi H, Katanforoush A, Torabi N, Najafabadi HS. PMID: 17240399.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    58. The case for an error minimizing set of coding amino acids. J Theor Biol. 2007 Feb 21; 244(4):737-44. Torabi N, Goodarzi H, Shateri Najafabadi H. PMID: 17069856.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    59. Importance of RNA secondary structure information for yeast donor and acceptor splice site predictions by neural networks. Comput Biol Chem. 2006 Feb; 30(1):50-7. Marashi SA, Goodarzi H, Sadeghi M, Eslahchi C, Pezeshk H. PMID: 16386465.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    60. The impact of including tRNA content on the optimality of the genetic code. Bull Math Biol. 2005 Nov; 67(6):1355-68. Goodarzi H, Najafabadi HS, Nejad HA, Torabi N. PMID: 16005951.
      View in: PubMed   Mentions: 3     Fields:    
    61. On the coevolution of genes and genetic code. Gene. 2005 Dec 05; 362:133-40. Goodarzi H, Shateri Najafabadi H, Torabi N. PMID: 16213111.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    62. On the optimality of the genetic code, with the consideration of coevolution theory by comparison of prominent cost measure matrices. J Theor Biol. 2005 Aug 07; 235(3):318-25. Goodarzi H, Najafabadi HS, Hassani K, Nejad HA, Torabi N. PMID: 15882694.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    63. Applying a neural network to predict the thermodynamic parameters for an expanded nearest-neighbor model. J Theor Biol. 2006 Feb 07; 238(3):657-65. Najafabadi HS, Goodarzi H, Torabi N, Banihosseini SS. PMID: 16061260.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    64. Designing a neural network for the constraint optimization of the fitness functions devised based on the load minimization of the genetic code. Biosystems. 2005 Aug; 81(2):91-100. Goodarzi H, Najafabadi HS, Torabi N. PMID: 15936137.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    65. Optimality of codon usage in Escherichia coli due to load minimization. J Theor Biol. 2005 Nov 21; 237(2):203-9. Najafabadi HS, Goodarzi H, Torabi N. PMID: 15932760.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    66. Correspondence regarding Bharanidharan et al., "Correlations between nucleotide frequencies and amino acid composition in 115 bacterial species". Biochem Biophys Res Commun. 2004 Dec 03; 325(1):1-2. Najafabadi HS, Goodarzi H. PMID: 15522192.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    67. On the optimality of the genetic code, with the consideration of termination codons. Biosystems. 2004 Nov; 77(1-3):163-73. Goodarzi H, Nejad HA, Torabi N. PMID: 15527955.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
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