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Roger Nicoll, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentCellular Molecular Pharmacology
Address600 16th Street
San Francisco CA 94158
Phone415-476-2018
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    Collapse Research 
    Collapse Research Activities and Funding
    2011 Excitatory Synapses and Brain Function GRC
    NIH/NIMH R13MH093928Jun 1, 2011 - Aug 31, 2015
    Role: Co-Principal Investigator
    Synaptic Glutamate Receptor Trafficking
    NIH/NIMH R01MH080379Jun 1, 2007 - Apr 30, 2017
    Role: Principal Investigator
    AMPA Receptor Subunits and Plasticity
    NIH/NIMH R01MH070957Mar 11, 2004 - Feb 29, 2020
    Role: Principal Investigator
    AMPA Receptor Subunits and Plasticity
    NIH/NIMH R56MH070957Mar 11, 2004 - Feb 28, 2015
    Role: Principal Investigator
    Synaptic signaling regulated by MALS family PDZ proteins
    NIH/NIMH R01MH070062Dec 1, 2003 - Nov 30, 2008
    Role: Principal Investigator
    ASSEMBLY AND TARGETING OF NEURAL RECEPTORS AND CHANNELS
    NIH/NIMH P50MH063981Aug 15, 2001 - Jul 31, 2007
    Role: Principal Investigator
    SYNAPTIC ACTIONS OF OPIOID PEPTIDES IN THE HIPPOCAMPUS
    NIH/NIDA R01DA010268Dec 15, 1996 - Nov 30, 2002
    Role: Principal Investigator
    LONGTERM CHANGES IN THE MAMMALIAN BRAIN
    NIH/NIMH P50MH048200Sep 1, 1991 - Aug 31, 2002
    Role: Co-Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    CENTRAL SEROTONIN RECEPTORS: IONIC AND MOLECULAR MECHAN
    NIH/NINDS R01NS024205Dec 1, 1986 - Nov 30, 1994
    Role: Principal Investigator
    NEUROTRANSMITTER EFFECTS ON LOCAL NEURONAL CIRCUITS
    NIH/NIMH R01MH038256Dec 1, 1983 - Nov 30, 1986
    Role: Principal Investigator
    LOCAL NEURONAL CIRCUITS IN THE CENTRAL NERVOUS SYSTEM
    NIH/NIMH K05MH000437Jun 1, 1983 - May 31, 1998
    Role: Principal Investigator
    LOCAL NEURONAL CIRCUITS IN THE CNS
    NIH/NIMH K02MH000437Jun 1, 1983 - May 31, 1988
    Role: Principal Investigator
    Cellular and Molecular Substrates of Synaptic Plasticity
    NIH/NIMH R37MH038256Jan 1, 1983 - Feb 28, 2017
    Role: Principal Investigator
    Function and development in the synapse
    NIH P01NS016033Apr 1, 1980 - Jun 30, 2009
    Role: Co-Investigator
    Predoctoral Training in Neurobiology
    NIH/NIGMS T32GM007449Sep 1, 1977 - Jun 30, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse In The News
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sheng N, Shi YS, Nicoll R. Amino-terminal domains of kainate receptors determine the differential dependence on Neto auxiliary subunits for trafficking. Proc Natl Acad Sci U S A. 2017 Jan 18. PMID: 28100490.
      View in: PubMed
    2. Levy JM, Nicoll R. MAGUK dynamics reveal regional and developmental specificity of synapse stability. J Physiol. 2016 Nov 8. PMID: 27861918.
      View in: PubMed
    3. Nguyen QA, Horn ME, Nicoll R. Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses. Elife. 2016 Nov 02; 5. PMID: 27805570.
      View in: PubMed
    4. Sheng N, Yang J, Silm K, Edwards RH, Nicoll R. A slow excitatory postsynaptic current mediated by a novel metabotropic glutamate receptor in CA1 pyramidal neurons. Neuropharmacology. 2017 Mar 15; 115:4-9. PMID: 27567940.
      View in: PubMed
    5. Won S, Incontro S, Nicoll R, Roche KW. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61. Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32):E4736-44. PMID: 27457929.
      View in: PubMed
    6. Herring BE, Nicoll R. Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking. Annu Rev Physiol. 2016 Feb 10; 78:351-65. PMID: 26863325.
      View in: PubMed
    7. Herring BE, Nicoll R. Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2264-9. PMID: 26858404.
      View in: PubMed
    8. Sheng N, Shi YS, Lomash RM, Roche KW, Nicoll R. Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1. Elife. 2015; 4. PMID: 26720915.
      View in: PubMed
    9. Chen X, Levy JM, Hou A, Winters C, Azzam R, Sousa AA, Leapman RD, Nicoll R, Reese TS. PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):E6983-92. PMID: 26604311.
      View in: PubMed
    10. Levy JM, Chen X, Reese TS, Nicoll R. Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss. Neuron. 2015 Aug 5; 87(3):534-48. PMID: 26247861; PMCID: PMC4596923 [Available on 08/05/16].
    11. Bemben MA, Shipman SL, Nicoll R, Roche KW. The cellular and molecular landscape of neuroligins. Trends Neurosci. 2015 Aug; 38(8):496-505. PMID: 26209464.
      View in: PubMed
    12. Herring BE, Silm K, Edwards RH, Nicoll R. Is Aspartate an Excitatory Neurotransmitter? J Neurosci. 2015 Jul 15; 35(28):10168-71. PMID: 26180193; PMCID: PMC4502257 [Available on 01/15/16].
    13. Lovero KL, Fukata Y, Granger AJ, Fukata M, Nicoll R. The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):E4129-37. PMID: 26178195; PMCID: PMC4522810 [Available on 01/28/16].
    14. Bemben MA, Nguyen QA, Wang T, Li Y, Nicoll R, Roche KW. Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2551-6. PMID: 25675530; PMCID: PMC4345621.
    15. Yamazaki M, Le Pichon CE, Jackson AC, Cerpas M, Sakimura K, Scearce-Levie K, Nicoll R. Relative contribution of TARPs ?-2 and ?-7 to cerebellar excitatory synaptic transmission and motor behavior. Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4):E371-9. PMID: 25583485; PMCID: PMC4313851.
    16. Incontro S, Asensio CS, Edwards RH, Nicoll R. Efficient, complete deletion of synaptic proteins using CRISPR. Neuron. 2014 Sep 3; 83(5):1051-7. PMID: 25155957; PMCID: PMC4195490.
    17. Granger AJ, Nicoll R. LTD expression is independent of glutamate receptor subtype. Front Synaptic Neurosci. 2014; 6:15. PMID: 25071549; PMCID: PMC4086023.
    18. Choy RW, Park M, Temkin P, Herring BE, Marley A, Nicoll R, von Zastrow M. Retromer mediates a discrete route of local membrane delivery to dendrites. Neuron. 2014 Apr 2; 82(1):55-62. PMID: 24698268; PMCID: PMC4029335.
    19. Fu Y, Tucciarone JM, Espinosa JS, Sheng N, Darcy DP, Nicoll R, Huang ZJ, Stryker MP. A cortical circuit for gain control by behavioral state. Cell. 2014 Mar 13; 156(6):1139-52. PMID: 24630718; PMCID: PMC4041382.
    20. Bemben MA, Shipman SL, Hirai T, Herring BE, Li Y, Badger JD, Nicoll R, Diamond JS, Roche KW. CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses. Nat Neurosci. 2014 Jan; 17(1):56-64. PMID: 24336150; PMCID: PMC3943352.
    21. Granger AJ, Nicoll R. Expression mechanisms underlying long-term potentiation: a postsynaptic view, 10 years on. Philos Trans R Soc Lond B Biol Sci. 2014 Jan 5; 369(1633):20130136. PMID: 24298139; PMCID: PMC3843869.
    22. Huganir RL, Nicoll R. AMPARs and synaptic plasticity: the last 25 years. Neuron. 2013 Oct 30; 80(3):704-17. PMID: 24183021; PMCID: PMC4195488.
    23. Shipman SL, Herring BE, Suh YH, Roche KW, Nicoll R. Distance-dependent scaling of AMPARs is cell-autonomous and GluA2 dependent. J Neurosci. 2013 Aug 14; 33(33):13312-9. PMID: 23946389; PMCID: PMC3742921.
    24. Lovero KL, Blankenship SM, Shi Y, Nicoll R. SynDIG1 promotes excitatory synaptogenesis independent of AMPA receptor trafficking and biophysical regulation. PLoS One. 2013; 8(6):e66171. PMID: 23785483; PMCID: PMC3681968.
    25. Lu W, Bushong EA, Shih TP, Ellisman MH, Nicoll R. The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function. Neuron. 2013 May 8; 78(3):433-9. PMID: 23664612; PMCID: PMC3666354.
    26. Herring BE, Shi Y, Suh YH, Zheng CY, Blankenship SM, Roche KW, Nicoll R. Cornichon proteins determine the subunit composition of synaptic AMPA receptors. Neuron. 2013 Mar 20; 77(6):1083-96. PMID: 23522044; PMCID: PMC3652566.
    27. Sanz-Clemente A, Gray JA, Ogilvie KA, Nicoll R, Roche KW. Activated CaMKII couples GluN2B and casein kinase 2 to control synaptic NMDA receptors. Cell Rep. 2013 Mar 28; 3(3):607-14. PMID: 23478024; PMCID: PMC3615108.
    28. Nicoll R, Roche KW. Long-term potentiation: peeling the onion. Neuropharmacology. 2013 Nov; 74:18-22. PMID: 23439383; PMCID: PMC3718856.
    29. Granger AJ, Shi Y, Lu W, Cerpas M, Nicoll R. LTP requires a reserve pool of glutamate receptors independent of subunit type. Nature. 2013 Jan 24; 493(7433):495-500. PMID: 23235828; PMCID: PMC3998843.
    30. Shipman SL, Nicoll R. Dimerization of postsynaptic neuroligin drives synaptic assembly via transsynaptic clustering of neurexin. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19432-7. PMID: 23129658; PMCID: PMC3511127.
    31. Lussier MP, Herring BE, Nasu-Nishimura Y, Neutzner A, Karbowski M, Youle RJ, Nicoll R, Roche KW. Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19426-31. PMID: 23129617; PMCID: PMC3511152.
    32. Chen BS, Gray JA, Sanz-Clemente A, Wei Z, Thomas EV, Nicoll R, Roche KW. SAP102 mediates synaptic clearance of NMDA receptors. Cell Rep. 2012 Nov 29; 2(5):1120-8. PMID: 23103165; PMCID: PMC3513525.
    33. Shipman SL, Nicoll R. A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP. Neuron. 2012 Oct 18; 76(2):309-16. PMID: 23083734; PMCID: PMC3998838.
    34. Gray JA, Nicoll R. Thinking outside the synapse: glycine at extrasynaptic NMDA receptors. Cell. 2012 Aug 3; 150(3):455-6. PMID: 22863001.
      View in: PubMed
    35. Sanz-Clemente A, Nicoll R, Roche KW. Diversity in NMDA receptor composition: many regulators, many consequences. Neuroscientist. 2013 Feb; 19(1):62-75. PMID: 22343826; PMCID: PMC3567917.
    36. Jackson AC, Nicoll R. Stargazing from a new vantage--TARP modulation of AMPA receptor pharmacology. J Physiol. 2011 Dec 15; 589(Pt 24):5909-10. PMID: 22174138; PMCID: PMC3286667.
    37. Gray JA, Shi Y, Usui H, During MJ, Sakimura K, Nicoll R. Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron. 2011 Sep 22; 71(6):1085-101. PMID: 21943605; PMCID: PMC3183990.
    38. Granger AJ, Gray JA, Lu W, Nicoll R. Genetic analysis of neuronal ionotropic glutamate receptor subunits. J Physiol. 2011 Sep 1; 589(Pt 17):4095-101. PMID: 21768264; PMCID: PMC3180569.
    39. Jackson AC, Milstein AD, Soto D, Farrant M, Cull-Candy SG, Nicoll R. Probing TARP modulation of AMPA receptor conductance with polyamine toxins. J Neurosci. 2011 May 18; 31(20):7511-20. PMID: 21593335; PMCID: PMC3164836.
    40. Shipman SL, Schnell E, Hirai T, Chen BS, Roche KW, Nicoll R. Functional dependence of neuroligin on a new non-PDZ intracellular domain. Nat Neurosci. 2011 Jun; 14(6):718-26. PMID: 21532576; PMCID: PMC3171182.
    41. Jackson AC, Nicoll R. The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunits. Neuron. 2011 Apr 28; 70(2):178-99. PMID: 21521608; PMCID: PMC3119519.
    42. Cavanaugh DJ, Chesler AT, Jackson AC, Sigal YM, Yamanaka H, Grant R, O'Donnell D, Nicoll R, Shah NM, Julius D, Basbaum AI. Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci. 2011 Mar 30; 31(13):5067-77. PMID: 21451044; PMCID: PMC3087977.
    43. Jackson AC, Nicoll R. Stargazin (TARP gamma-2) is required for compartment-specific AMPA receptor trafficking and synaptic plasticity in cerebellar stellate cells. J Neurosci. 2011 Mar 16; 31(11):3939-52. PMID: 21411637; PMCID: PMC3104604.
    44. Lu W, Isozaki K, Roche KW, Nicoll R. Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1. Proc Natl Acad Sci U S A. 2010 Dec 21; 107(51):22266-71. PMID: 21135237; PMCID: PMC3009812.
    45. Goold CP, Nicoll R. Single-cell optogenetic excitation drives homeostatic synaptic depression. Neuron. 2010 Nov 4; 68(3):512-28. PMID: 21040851; PMCID: PMC3111089.
    46. Lu W, Gray JA, Granger AJ, During MJ, Nicoll R. Potentiation of synaptic AMPA receptors induced by the deletion of NMDA receptors requires the GluA2 subunit. J Neurophysiol. 2011 Feb; 105(2):923-8. PMID: 20980546; PMCID: PMC3059181.
    47. Juge N, Gray JA, Omote H, Miyaji T, Inoue T, Hara C, Uneyama H, Edwards RH, Nicoll R, Moriyama Y. Metabolic control of vesicular glutamate transport and release. Neuron. 2010 Oct 6; 68(1):99-112. PMID: 20920794; PMCID: PMC2978156.
    48. Shi Y, Suh YH, Milstein AD, Isozaki K, Schmid SM, Roche KW, Nicoll R. Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16315-9. PMID: 20805473; PMCID: PMC2941340.
    49. Tzingounis AV, Heidenreich M, Kharkovets T, Spitzmaul G, Jensen HS, Nicoll R, Jentsch TJ. The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus. Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22):10232-7. PMID: 20534576; PMCID: PMC2890451.
    50. Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll R, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE, Wu C, Wunsch C, Zoback ML. Climate change and the integrity of science. Science. 2010 May 7; 328(5979):689-90. PMID: 20448167.
      View in: PubMed
    51. Howard MA, Elias GM, Elias LA, Swat W, Nicoll R. The role of SAP97 in synaptic glutamate receptor dynamics. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3805-10. PMID: 20133708; PMCID: PMC2840522.
    52. Fukata Y, Lovero KL, Iwanaga T, Watanabe A, Yokoi N, Tabuchi K, Shigemoto R, Nicoll R, Fukata M. Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3799-804. PMID: 20133599; PMCID: PMC2840530.
    53. Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll R, Edwards RH. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 2010 Jan 14; 65(1):66-79. PMID: 20152114; PMCID: PMC3119527.
    54. Milstein AD, Nicoll R. TARP modulation of synaptic AMPA receptor trafficking and gating depends on multiple intracellular domains. Proc Natl Acad Sci U S A. 2009 Jul 7; 106(27):11348-51. PMID: 19549880; PMCID: PMC2708767.
    55. Shi Y, Lu W, Milstein AD, Nicoll R. The stoichiometry of AMPA receptors and TARPs varies by neuronal cell type. Neuron. 2009 Jun 11; 62(5):633-40. PMID: 19524523; PMCID: PMC3119531.
    56. Lu W, Shi Y, Jackson AC, Bjorgan K, During MJ, Sprengel R, Seeburg PH, Nicoll R. Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach. Neuron. 2009 Apr 30; 62(2):254-68. PMID: 19409270; PMCID: PMC3632349.
    57. Jackson AC, Nicoll R. Neuroscience: AMPA receptors get 'pickled'. Nature. 2009 Apr 2; 458(7238):585-6. PMID: 19340072; PMCID: PMC2716117.
    58. Elias GM, Elias LA, Apostolides PF, Kriegstein AR, Nicoll R. Differential trafficking of AMPA and NMDA receptors by SAP102 and PSD-95 underlies synapse development. Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20953-8. PMID: 19104036; PMCID: PMC2634944.
    59. Tzingounis AV, Nicoll R. Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19974-9. PMID: 19060215; PMCID: PMC2604953.
    60. Kerchner GA, Nicoll R. Silent synapses and the emergence of a postsynaptic mechanism for LTP. Nat Rev Neurosci. 2008 Nov; 9(11):813-25. PMID: 18854855; PMCID: PMC2819160.
    61. Menuz K, Nicoll R. Loss of inhibitory neuron AMPA receptors contributes to ataxia and epilepsy in stargazer mice. J Neurosci. 2008 Oct 15; 28(42):10599-603. PMID: 18923036; PMCID: PMC3164835.
    62. Menuz K, O'Brien JL, Karmizadegan S, Bredt DS, Nicoll R. TARP redundancy is critical for maintaining AMPA receptor function. J Neurosci. 2008 Aug 27; 28(35):8740-6. PMID: 18753375; PMCID: PMC3159041.
    63. Milstein AD, Nicoll R. Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits. Trends Pharmacol Sci. 2008 Jul; 29(7):333-9. PMID: 18514334; PMCID: PMC2819157.
    64. Menuz K, Kerchner GA, O'Brien JL, Nicoll R. Critical role for TARPs in early development despite broad functional redundancy. Neuropharmacology. 2009 Jan; 56(1):22-9. PMID: 18634809; PMCID: PMC3111090.
    65. Bautista DM, Sigal YM, Milstein AD, Garrison JL, Zorn JA, Tsuruda PR, Nicoll R, Julius D. Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. Nat Neurosci. 2008 Jul; 11(7):772-9. PMID: 18568022; PMCID: PMC3072296.
    66. Adesnik H, Li G, During MJ, Pleasure SJ, Nicoll R. NMDA receptors inhibit synapse unsilencing during brain development. Proc Natl Acad Sci U S A. 2008 Apr 8; 105(14):5597-602. PMID: 18375768; PMCID: PMC2291097.
    67. Li G, Adesnik H, Li J, Long J, Nicoll R, Rubenstein JL, Pleasure SJ. Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci. 2008 Jan 30; 28(5):1085-98. PMID: 18234887; PMCID: PMC3072297.
    68. Panicker S, Brown K, Nicoll R. Synaptic AMPA receptor subunit trafficking is independent of the C terminus in the GluR2-lacking mouse. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):1032-7. PMID: 18195349; PMCID: PMC2242677.
    69. Tomita S, Byrd RK, Rouach N, Bellone C, Venegas A, O'Brien JL, Kim KS, Olsen O, Nicoll R, Bredt DS. AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18784-8. PMID: 18000041; PMCID: PMC2141854.
    70. Menuz K, Stroud RM, Nicoll R, Hays FA. TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. Science. 2007 Nov 2; 318(5851):815-7. PMID: 17975069.
      View in: PubMed
    71. Milstein AD, Zhou W, Karimzadegan S, Bredt DS, Nicoll R. TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Neuron. 2007 Sep 20; 55(6):905-18. PMID: 17880894; PMCID: PMC3167227.
    72. Bellone C, Nicoll R. Rapid bidirectional switching of synaptic NMDA receptors. Neuron. 2007 Sep 6; 55(5):779-85. PMID: 17785184.
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    73. Kam K, Nicoll R. Excitatory synaptic transmission persists independently of the glutamate-glutamine cycle. J Neurosci. 2007 Aug 22; 27(34):9192-200. PMID: 17715355.
      View in: PubMed
    74. Elias GM, Nicoll R. Synaptic trafficking of glutamate receptors by MAGUK scaffolding proteins. Trends Cell Biol. 2007 Jul; 17(7):343-52. PMID: 17644382.
      View in: PubMed
    75. Kato AS, Zhou W, Milstein AD, Knierman MD, Siuda ER, Dotzlaf JE, Yu H, Hale JE, Nisenbaum ES, Nicoll R, Bredt DS. New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. J Neurosci. 2007 May 2; 27(18):4969-77. PMID: 17475805.
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    76. Adesnik H, Nicoll R. Conservation of glutamate receptor 2-containing AMPA receptors during long-term potentiation. J Neurosci. 2007 Apr 25; 27(17):4598-602. PMID: 17460072.
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    77. Tzingounis AV, Kobayashi M, Takamatsu K, Nicoll R. Hippocalcin gates the calcium activation of the slow afterhyperpolarization in hippocampal pyramidal cells. Neuron. 2007 Feb 15; 53(4):487-93. PMID: 17296551; PMCID: PMC1832111.
    78. Tzingounis AV, Nicoll R. Arc/Arg3.1: linking gene expression to synaptic plasticity and memory. Neuron. 2006 Nov 9; 52(3):403-7. PMID: 17088207.
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    79. Elias GM, Funke L, Stein V, Grant SG, Bredt DS, Nicoll R. Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. Neuron. 2006 Oct 19; 52(2):307-20. PMID: 17046693.
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    80. Fukata Y, Adesnik H, Iwanaga T, Bredt DS, Nicoll R, Fukata M. Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission. Science. 2006 Sep 22; 313(5794):1792-5. PMID: 16990550.
      View in: PubMed
    81. Tomita S, Shenoy A, Fukata Y, Nicoll R, Bredt DS. Stargazin interacts functionally with the AMPA receptor glutamate-binding module. Neuropharmacology. 2007 Jan; 52(1):87-91. PMID: 16919685.
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    320. Nicoll R, Padjen A, Barker JL. Analysis of amino acid responses on frog motoneurones. Neuropharmacology. 1976 Jan; 15(1):45-53. PMID: 1256640.
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    321. Eccles JC, Nicoll R, Rantucci T, Táboríková H, Willey TJ. Topographic studies on medial reticular nucleus. J Neurophysiol. 1976 Jan; 39(1):109-18. PMID: 1249596.
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    322. Nicoll R, Eccles JC, Oshima T, Rubia F. Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates. Nature. 1975 Dec 18; 258(5536):625-7. PMID: 1207741.
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    323. Nicoll R. The action of acetylcholine antagonists on amino acid responses in the frog spinal cord in vitro. Br J Pharmacol. 1975 Dec; 55(4):449-58. PMID: 1082355; PMCID: PMC1666741.
    324. Nicoll R. Pentobarbital: action on frog motoneurons. Brain Res. 1975 Oct 10; 96(1):119-23. PMID: 1174993.
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    325. Nicoll R. Gamma-aminobutyrylcholine and GABA receptors on primary afferents in the frog spinal cord. J Pharm Pharmacol. 1975 Jul; 27(7):529-31. PMID: 239160.
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    326. Eccles JC, Nicoll R, Táboríková H, Willey TJ. Medial recticular neurons projecting Rostrally. J Neurophysiol. 1975 May; 38(3):531-8. PMID: 1127455.
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    327. Eccles JC, Nicoll R, Schwarz WF, Táboriková H, Willey TJ. Reticulospinal neurons with and without monosynaptic inputs from cerebellar nuclei. J Neurophysiol. 1975 May; 38(3):513-30. PMID: 1127454.
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    328. Nicoll R. Presynaptic action of barbiturates in the frog spinal cord. Proc Natl Acad Sci U S A. 1975 Apr; 72(4):1460-3. PMID: 1079349; PMCID: PMC432555.
    329. Barker JL, Nicoll R, Padjen A. Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses. J Physiol. 1975 Mar; 245(3):521-36. PMID: 1079871; PMCID: PMC1330803.
    330. Barker JL, Nicoll R, Padjen A. Studies on convulsants in the isolated frog spinal cord. II. Effects on root potentials. J Physiol. 1975 Mar; 245(3):537-48. PMID: 167156; PMCID: PMC1330804.
    331. Nicoll R, Barker JL. Effect of strychnine on dorsal root potentials and amino acid responses in frog spinal cord. Nat New Biol. 1973 Dec 19; 246(155):224-5. PMID: 4519608.
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    332. Barker JL, Nicoll R. The pharmacology and ionic dependency of amino acid responses in the frog spinal cord. J Physiol. 1973 Jan; 228(2):259-77. PMID: 4346988; PMCID: PMC1331296.
    333. Barker JL, Nicoll R. Gamma-aminobutyric acid: role in primary afferent depolarization. Science. 1972 Jun 2; 176(4038):1043-5. PMID: 4338197.
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    334. Nicoll R. The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb. J Physiol. 1972 Jun; 223(3):803-14. PMID: 5045741; PMCID: PMC1331482.
    335. Bloom FE, Hoffer BJ, Siggins GR, Barker JL, Nicoll R. Effects of serotonin on central neurons: microiontophoretic administration. Fed Proc. 1972 Jan-Feb; 31(1):97-106. PMID: 4333253.
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    336. Nicoll R. Olfactory nerves and their excitatory action in the olfactory bulb. Exp Brain Res. 1972; 14(2):185-97. PMID: 5016588.
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    337. Nicoll R, Barker JL. The pharmacology of recurrent inhibition in the supraoptic neurosecretory system. Brain Res. 1971 Dec 24; 35(2):501-11. PMID: 4400088.
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    338. Nicoll R. Pharmacological evidence for GABA as the transmitter in granule cell inhibition in the olfactory bulb. Brain Res. 1971 Dec 10; 35(1):137-49. PMID: 4332422.
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    339. Barker JL, Crayton JW, Nicoll R. Antidromic and orthodromic responses of paraventricular and supraoptic neurosecretory cells. Brain Res. 1971 Oct 29; 33(2):353-66. PMID: 5134925.
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    340. Nicoll R, Barker JL. Excitation of supraoptic neurosecretory cells by angiotensin II. Nat New Biol. 1971 Oct 6; 233(40):172-4. PMID: 4330552.
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    341. Barker JL, Crayton JW, Nicoll R. Noradrenaline and acetylcholine responses of supraoptic neurosecretory cells. J Physiol. 1971 Oct; 218(1):19-32. PMID: 4399777; PMCID: PMC1331582.
    342. Nicoll R. Recurrent excitation of secondary olfactory neurons: a possible mechanism for signal amplification. Science. 1971 Feb 26; 171(3973):824-6. PMID: 5541166.
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    343. Barker JL, Crayton JW, Nicoll R. Supraoptic neurosecretory cells: adrenergic and cholinergic sensitivity. Science. 1971 Jan 15; 171(3967):208-10. PMID: 4395231.
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    344. Barker JL, Crayton JW, Nicoll R. Supraopticneurosecretory cells: autonomic modulation. Science. 1971 Jan 15; 171(3967):206-7. PMID: 5538831.
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    345. Nicoll R. Identification of tufted cells in the olfactory bulb. Nature. 1970 Aug 8; 227(5258):623-5. PMID: 5429297.
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    346. Nicoll R. Recurrent excitatory pathways of anterior commissure and mitral cell axons in the olfactory bulb. Brain Res. 1970 May 4; 19(3):491-3. PMID: 4315456.
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    347. Nicoll R. Inhibitory mechanisms in the rabbit olfactory bulb: dendrodendritic mechanisms. Brain Res. 1969 Jun; 14(1):157-72. PMID: 5783107.
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