Meghana Gadgil, MD, MPH

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address1545 Divisadero Street, #311
San Francisco CA 94115
ORCID ORCID Icon0000-0001-8638-0048 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Rutgers New Jersey Medical School, Newark, NJMD
    Warren Alpert Medical School at Brown University, Providence, RIResidencyInternal Medicine
    Johns Hopkins Bloomberg School of Public HealthMPH
    Johns Hopkins General Internal Medicine Fellowship
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    My long-term goal is to prevent cardiometabolic disease in high-risk populations through a three-level approach: 1) clinical investigation of metabolomic processes at the individual level 2) improvements in chronic disease prevention inside the primary care office and 3) lifestyle changes with a focus on practical dietary interventions in the lived environment.

    At the individual level:
    My clinical research activities center on the metabolic processes connecting dietary intake and incident diabetes which are not yet well-characterized. I believe that further work with "omics" technologies can help to delineate the paths between diet and diabetes and identify targets for intervention.

    Inside the PCP's office:
    I am developing a program to improve postpartum transitions to primary care for women with gestational diabetes. In this program, we are identifying women with a pregnancy affected by GDM who are at high risk of transition to type 2 diabetes. We are then designing programs within our medical record system to track, improve postpartum follow-up and enroll patients into primary care.

    In the lived environment:
    A current research award from the Mount Zion Health Fund is supporting work improving the knowledge and uptake of prediabetes resources in the community.

    I have completed a pilot intervention study enrolling participants with prediabetes to evaluate the impact evaluation walnut intake on dietary quality, measures of prediabetes and metabolite expression.

    I am committed to work in the prevention of diabetes as it disproportionally impacts racial and ethnic minority populations. I also focus on research into the specific risk factors that women face in the development of diabetes, particularly those in the postpartum period. I feel strongly that each population should have appropriate and equitable guidance for a personalized care plan for the prevention of diabetes.

    My future goals are to extend and individualize current knowledge about beneficial dietary and lifestyle interventions to prevent cardiometabolic disease, and to use digital tools and metabolomics to monitor responsiveness to these programs.

    Collapse Research 
    Collapse Research Activities and Funding
    Associations of Targeted Metabolites with Protein, Saturated Fat and Glucose Homeostasis
    NIDDK R03DK132307Apr 1, 2022 - Mar 31, 2024
    Role: Principal Investigator
    Prevention of Type 2 Diabetes through Diet and Metabolomics
    NIH K23DK119404Aug 1, 2019 - Nov 30, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Predictors of weight and waist gain in US South Asians: Findings from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. Res Sq. 2024 Mar 28. Seetharaman S, Allen I, Gadgil M, Sriniva S, Topor L, Kanaya A. PMID: 38585953; PMCID: PMC10996820.
      View in: PubMed   Mentions:
    2. Abstract P479: Whole Grain and Refined Grain Intake and Associations With Adiposity, Inflammation, and Incident Type 2 Diabetes Among Adults of South Asian Ancestry in the MASALA Cohort. Circulation. 2024 Mar 19; 149(Suppl_1):ap479-ap479. Sawicki SC, Kanaya KA, Kandula KN, Gadgil GM, Bhupathiraju BS. .
      View in: Publisher Site   Mentions:
    3. Abstract P114: Micro RNAs Associated With Clinical Classifiers of Gender, Race and Ethnicity in the Diabetes Prevention Program. Circulation. 2024 Mar 19; 149(Suppl_1):ap114-ap114. Stroebel SB, Zhang ZL, Aouizerat AB, Lewis LK, Longoria LK, Gadgil GM, Flowers FE. .
      View in: Publisher Site   Mentions:
    4. Inverse association between total bilirubin and type 2 diabetes in U.S. South Asian males but not females. PLoS One. 2024; 19(2):e0297685. Visaria A, Kanaya A, Setoguchi S, Gadgil M, Satagopan J. PMID: 38324554; PMCID: PMC10849233.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Adipose tissue-derived metabolite risk scores and risk for type 2 diabetes in South Asians. Int J Obes (Lond). 2024 Jan 20. Gadgil MD, Cheng J, Herrington DM, Kandula NR, Kanaya AM. PMID: 38245659.
      View in: PubMed   Mentions:    Fields:    
    6. Reflecting on a Year at the Helm of Diabetes Care. Diabetes Care. 2024 Jan 01; 47(1):4-6. Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Fitzpatrick SL, Gadgil MD, Gastaldelli A, Gloyn AL, Green JB, Jastreboff AM, Kanaya AM, Kandula NR, Kovesdy CP, Laiteerapong N, Nadeau KJ, Pettus J, Pop-Busui R, Posey JE, Powe CE, Rebholz CM, Rickels MR, Sattar N, Shaw JE, Sims EK, Utzschneider KM, Vella A, Zhang C. PMID: 38117988.
      View in: PubMed   Mentions:    Fields:    
    7. Association of lipoprotein subfractions with incidence of type 2 diabetes among five U.S. Race and Ethnic groups: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multi-Ethnic study of Atherosclerosis (MESA). Diabetes Res Clin Pract. 2023 Oct; 204:110926. Gadgil MD, Herrington DM, Singh SK, Kandula NR, Kanaya AM. PMID: 37777016; PMCID: PMC10886444.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Untargeted metabolomic analysis investigating links between unprocessed red meat intake and markers of inflammation. Am J Clin Nutr. 2023 11; 118(5):989-999. Wood AC, Graca G, Gadgil M, Senn MK, Allison MA, Tzoulaki I, Greenland P, Ebbels T, Elliott P, Goodarzi MO, Tracy R, Rotter JI, Herrington D. PMID: 37660929; PMCID: PMC10797554.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Concordance between Dash Diet and Hypertension: Results from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. Nutrients. 2023 Aug 17; 15(16). Hussain BM, Deierlein AL, Kanaya AM, Talegawkar SA, O'Connor JA, Gadgil MD, Lin Y, Parekh N. PMID: 37630801; PMCID: PMC10458588.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Associations between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis. J Nutr. 2023 10; 153(10):2797-2807. Wood AC, Goodarzi MO, Senn MK, Gadgil MD, Graca G, Allison MA, Tzoulaki I, Mi MY, Greenland P, Ebbels T, Elliott P, Tracy RP, Herrington DM, Rotter JI. PMID: 37562669; PMCID: PMC10925911.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    11. OR02-05-23 Untargeted Metabolomic Analysis Reveals Inverse Associations Between Red Meat Intake and Two Anti-Inflammatory Amino Acids. Current Developments in Nutrition. 2023 Jul 1; 7:101326. Wood WA, Senn SM, Gadgil GM, Graca GG, Allison AM, Tzoulaki TI, Greenland GP, Ebbels ET, Elliott EP, Goodarzi GM, Tracy TR, Rotter RJ, Herrington HD. .
      View in: Publisher Site   Mentions:
    12. Association of Physical Activity and Dietary Quality with Weight, Ectopic Fat, and Insulin Resistance in South Asian Men and Women: The MASALA Study. Journal of Clinical Lipidology. 2023 Jul 1; 17(4):e49-e50. Ponir PC, Chevli CP, Kanaya KA, Gadgil GM, Rodriguez RL, Upadhya UB, Mongraw-Chaffin MM. .
      View in: Publisher Site   Mentions:
    13. 603-P: Changes in Insulin Resistance by Protein Source and Level of Saturated Fat—An Analysis of the Animal and Plant Protein and Cardiovascular Health (APPROACH) Trial. Diabetes. 2023 Jun 20; 72(Supplement_1). GADGIL GM, KRAUSS KR. .
      View in: Publisher Site   Mentions:
    14. 1399-P: Lipoprotein Subfractions and Type 2 Diabetes Incidence in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and Multiethnic Study of Atherosclerosis (MESA) Cohorts. Diabetes. 2023 Jun 20; 72(Supplement_1). GADGIL GM, HERRINGTON HD, SINGH SS, KANDULA KN, KANAYA KA. .
      View in: Publisher Site   Mentions:
    15. 205-LB: Using Metabolomic Biomarkers to Understand Relationships between Avocado Intake and Dysglycemia. Diabetes. 2023 Jun 20; 72(Supplement_1). WOOD WA, GOODARZI GM, GADGIL GM, ALLISON AM, GRAÇA GG, MI MM, GREENLAND GP, HERRINGTON HD, ROTTER RJ. .
      View in: Publisher Site   Mentions:
    16. Metabolomic Profile of the Healthy Eating Index-2015 in the Multiethnic Study of Atherosclerosis. J Nutr. 2023 08; 153(8):2174-2180. Gadgil MD, Wood AC, Karaman I, Graça G, Tzoulaki I, Zhong VW, Greenland P, Kanaya AM, Herrington DM. PMID: 37271414; PMCID: PMC10493432.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Abstract MP12: Dash Diet and Its Components is Associated With Visceral Fat Area and Hepatic Attenuation Among South Asian Adults in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study (2010-2013). Circulation. 2023 Feb 28; 147(Suppl_1):amp12-amp12. Hussain HB, Deierlein DA, Talegawkar TS, O'Connor OJ, Gadgil GM, Kanaya KA, Kandula KN, Lin LY, Parekh PN. .
      View in: Publisher Site   Mentions:
    18. "The Times They Are A-Changin'" at Diabetes Care. Diabetes Care. 2023 01 01; 46(1):3-5. Kahn SE, Anderson CAM, Buse JB, Selvin E, Angell SY, Aroda VR, Castle JR, Cheng AYY, Danne T, Echouffo-Tcheugui JB, Florez JC, Gadgil MD, Gastaldelli A, Green JB, Jastreboff AM, Kanaya AM, Kandula NR, Kovesdy CP, Laiteerapong N, Nadeau KJ, Pop-Busui R, Powe CE, Rebholz CM, Rickels MR, Sattar N, Shaw JE, Sims EK, Utzschneider KM, Vella A, Zhang C. PMID: 36548704.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Prepregnancy Protein Source and BCAA Intake Are Associated with Gestational Diabetes Mellitus in the CARDIA Study. Int J Environ Res Public Health. 2022 10 29; 19(21). Gadgil MD, Ingram KH, Appiah D, Rudd J, Whitaker KM, Bennett WL, Shikany JM, Jacobs DR, Lewis CE, Gunderson EP. PMID: 36361016; PMCID: PMC9658365.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    20. Diet Patterns Are Associated With Circulating Metabolites and Lipid Profiles of South Asians in the United States. J Nutr. 2022 Aug 30. Gadgil MD, Kanaya AM, Sands C, Chekmeneva E, Lewis MR, Kandula NR, Herrington DM. PMID: 36040341.
      View in: PubMed   Mentions:    Fields:    
    21. Diet Patterns Are Associated with Circulating Metabolites and Lipid Profiles of South Asians in the United States. J Nutr. 2022 11; 152(11):2358-2366. Gadgil MD, Kanaya AM, Sands C, Chekmeneva E, Lewis MR, Kandula NR, Herrington DM. PMID: 36774102; PMCID: PMC10157813.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    22. Associations of NAFLD with circulating ceramides and impaired glycemia. Diabetes Res Clin Pract. 2022 Apr; 186:109829. Gadgil MD, Sarkar M, Sands C, Lewis MR, Herrington DM, Kanaya AM. PMID: 35292328; PMCID: PMC9082931.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Circulating metabolites and lipids are associated with glycaemic measures in South Asians. Diabet Med. 2021 02; 38(2):e14494. Gadgil MD, Kanaya AM, Sands C, Lewis MR, Kandula NR, Herrington DM. PMID: 33617033; PMCID: PMC8115216.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Acculturation is Associated with Dietary Patterns in South Asians in America. J Immigr Minor Health. 2020 Dec; 22(6):1135-1140. Gadgil MD, Kandula NR, Kanaya AM. PMID: 32358772; PMCID: PMC7968473.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Social network characteristics are correlated with dietary patterns among middle aged and older South Asians living in the United States (U.S.). BMC Nutr. 2020; 6:40. Talegawkar SA, Lancki N, Jin Y, Siddique J, Gadgil M, Kanaya AM, Schneider JA, Van Horn L, De Koning L, Kandula NR. PMID: 32944264; PMCID: PMC7488332.
      View in: PubMed   Mentions: 3  
    26. Dietary Quality and Glycemic Control Among Women with Gestational Diabetes Mellitus. J Womens Health (Larchmt). 2019 02; 28(2):178-184. Gadgil MD, Ehrlich SF, Zhu Y, Brown SD, Hedderson MM, Crites Y, Ferrara A. PMID: 30376391; PMCID: PMC6390645.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    27. Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk. J Nutr. 2018 07 01; 148(7):1150-1159. Bhupathiraju SN, Guasch-Ferré M, Gadgil MD, Newgard CB, Bain JR, Muehlbauer MJ, Ilkayeva OR, Scholtens DM, Hu FB, Kanaya AM, Kandula NR. PMID: 29893901; PMCID: PMC6251517.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    28. The Association of Religious Affiliation with Overweight/Obesity Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. J Relig Health. 2018 Feb; 57(1):33-46. Bharmal NH, McCarthy WJ, Gadgil MD, Kandula NR, Kanaya AM. PMID: 27460674; PMCID: PMC5269531.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    29. Type 2 diabetes after gestational diabetes mellitus in South Asian women in the United States. Diabetes Metab Res Rev. 2017 07; 33(5). Gadgil MD, Oza-Frank R, Kandula NR, Kanaya AM. PMID: 28224756; PMCID: PMC5495618.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Psychosocial Factors Associated with Subclinical Atherosclerosis in South Asians: The MASALA Study. J Immigr Minor Health. 2016 12; 18(6):1317-1327. Shah BM, Shah S, Kandula NR, Gadgil MD, Kanaya AM. PMID: 26897179; PMCID: PMC4992471.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    31. Circulating micrornas associated with glycemic impairment and progression in Asian Indians. Biomark Res. 2015; 3:22. Flowers E, Gadgil M, Aouizerat BE, Kanaya AM. PMID: 26966540; PMCID: PMC4785747.
      View in: PubMed   Mentions: 21  
    32. Dietary intakes among South Asian adults differ by length of residence in the USA. Public Health Nutr. 2016 Feb; 19(2):348-55. Talegawkar SA, Kandula NR, Gadgil MD, Desai D, Kanaya AM. PMID: 25990446; PMCID: PMC4654701.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    33. Dietary patterns are associated with metabolic risk factors in South Asians living in the United States. J Nutr. 2015 Jun; 145(6):1211-7. Gadgil MD, Anderson CA, Kandula NR, Kanaya AM. PMID: 25904730; PMCID: PMC4442115.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimals
    34. Abstract P030: Traditional Cultural Beliefs and Length of Residence in the United States are Associated With Dietary Intakes Among South Asians. Circulation. 2015 Mar 10; 131(suppl_1). Talegawkar TS, Kandula KN, Gadgil GM, Desai DD, Kanaya KA. .
      View in: Publisher Site   Mentions:
    35. Abstract P300: Circulating MicroRNAs Associated with Glycemic Impairment and Progression in Asian Indians. Circulation. 2015 Mar 10; 131(suppl_1). Flowers FE, Aouizerat AB, Gadgil GM, Kanaya KA. .
      View in: Publisher Site   Mentions:
    36. Do static and dynamic insulin resistance indices perform similarly in predicting pre-diabetes and type 2 diabetes? Diabetes Res Clin Pract. 2014 Aug; 105(2):245-50. Liu R, Christoffel KK, Brickman WJ, Liu X, Gadgil M, Wang G, Zimmerman D, Chen Q, Wang B, Li Z, Xing H, Xu X, Wang X. PMID: 24882014; PMCID: PMC4138243.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    37. Dietary patterns in Asian Indians in the United States: an analysis of the metabolic syndrome and atherosclerosis in South Asians Living in America study. J Acad Nutr Diet. 2014 Feb; 114(2):238-243. Gadgil MD, Anderson CAM, Kandula NR, Kanaya AM. PMID: 24295929; PMCID: PMC3947024.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    38. Laboratory testing for and diagnosis of nutritional deficiencies in pregnancy before and after bariatric surgery. J Womens Health (Larchmt). 2014 Feb; 23(2):129-37. Gadgil MD, Chang HY, Richards TM, Gudzune KA, Huizinga MM, Clark JM, Bennett WL. PMID: 24102519; PMCID: PMC3922135.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    39. Screening and diagnosis of micronutrient deficiencies before and after bariatric surgery. Obes Surg. 2013 Oct; 23(10):1581-9. Gudzune KA, Huizinga MM, Chang HY, Asamoah V, Gadgil M, Clark JM. PMID: 23515975; PMCID: PMC3740071.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    40. Caring for Women with Pregnancy after Bariatric Surgery. Bariatric Surgical Practice and Patient Care. 2013 Sep 1; 8(3):119-120. Gadgil GM, Bennett BW. .
      View in: Publisher Site   Mentions:
    41. The effects of carbohydrate, unsaturated fat, and protein intake on measures of insulin sensitivity: results from the OmniHeart trial. Diabetes Care. 2013 May; 36(5):1132-7. Gadgil MD, Appel LJ, Yeung E, Anderson CA, Sacks FM, Miller ER. PMID: 23223345; PMCID: PMC3631872.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    42. Sexual ramifications of medical illness. Clin Obstet Gynecol. 2009 Dec; 52(4):691-701. Perez K, Gadgil M, Dizon DS. PMID: 20393421.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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