Theresa O'Brien, PhD

Title(s)Associate Chancellor, Office of the Chancellor
SchoolChancellor/EVC/FAS
Address550 16th Street
San Francisco CA 94158
Phone415-514-1455
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.2007 Graduate Division (Biochemistry)
    Williams College B.A.2002Biology
    University of California, San Francisco 2021Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    Theresa O'Brien, PhD, was appointed Associate Chancellor at the University of California, San Francisco (UCSF) in September 2014, having served as Interim Assistant Chancellor for UCSF and Associate Dean for Research Strategy in the School of Medicine. In her current role, she acts as an advisor to and designate of the Chancellor, leading initiatives in support of UCSF’s operational and strategic priorities. O’Brien is accountable for a wide range of activities related to UCSF governance structure, strategic planning, emergent issues, the Chancellor’s Executive Team and Chancellor’s Cabinet. In all aspects of her work, she partners closely with fellow executive team and cabinet members as well as internal and external stakeholders to further UCSF’s mission.

    O’Brien is also an Assistant Adjunct Professor in the Department of Cellular and Molecular Pharmacology. Her research and teaching interests primarily focus on career and professional development for graduate students and postdoctoral scholars. From 2010-2018, she directed the Graduate Student Internships for Career Exploration (GSICE) program, which provides career path education, career planning, and internship opportunities for UCSF’s basic and biomedical PhD students, and she is co-PI on a grant from the NIH to provide resources for PhD students and postdocs to explore career options and support for faculty mentors through the Motivating INformed Decisions (MIND) program. She is also involved in advancing precision medicine and related science policy issues at UCSF.

    Theresa is a graduate of UCSF's Tetrad Graduate Program and completed her doctoral work in biochemistry in the laboratory of Jim McKerrow, MD, PhD. A Northern California native, she graduated Summa Cum Laude with a BA in Biology from Williams College in Williamstown, MA.

    Collapse Research 
    Collapse Research Activities and Funding
    Motivating INformed Decisions (MIND): Careers for the Future Biomedical Workforce
    NIH DP7OD018420Sep 20, 2013 - Nov 30, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Applying Experiential Learning to Career Development Training for Biomedical Graduate Students and Postdocs: Perspectives on Program Development and Design. CBE Life Sci Educ. 2020 09; 19(3):es7. Van Wart A, O'Brien TC, Varvayanis S, Alder J, Greenier J, Layton RL, Stayart CA, Wefes I, Brady AE. PMID: 32822277.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. Internship Experiences Contribute to Confident Career Decision Making for Doctoral Students in the Life Sciences. CBE Life Sci Educ. 2018; 17(1). Schnoes AM, Caliendo A, Morand J, Dillinger T, Naffziger-Hirsch M, Moses B, Gibeling JC, Yamamoto KR, Lindstaedt B, McGee R, O'Brien TC. PMID: 29449270.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    3. The origin and implementation of the Broadening Experiences in Scientific Training programs: an NIH common fund initiative. FASEB J. 2016 Feb; 30(2):507-14. Meyers FJ, Mathur A, Fuhrmann CN, O'Brien TC, Wefes I, Labosky PA, Duncan DS, August A, Feig A, Gould KL, Friedlander MJ, Schaffer CB, Van Wart A, Chalkley R. PMID: 26432783.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    4. Precision medicine: Beyond the inflection point. Sci Transl Med. 2015 Aug 12; 7(300):300ps17. Hawgood S, Hook-Barnard IG, O'Brien TC, Yamamoto KR. PMID: 26268311.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    5. Transforming training to reflect the workforce. Sci Transl Med. 2015 Apr 29; 7(285):285ed4. Mathur A, Meyers FJ, Chalkley R, O'Brien TC, Fuhrmann CN. PMID: 25925677.
      View in: PubMed   Mentions: 9     Fields:    
    6. Commentary: Team science. Acad Med. 2013 Feb; 88(2):156-7. O'Brien T, Yamamoto K, Hawgood S. PMID: 23361027.
      View in: PubMed   Mentions: 4     Fields:    
    7. RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model. PLoS Negl Trop Dis. 2008 Sep 24; 2(9):e298. Abdulla MH, O'Brien T, Mackey ZB, Sajid M, Grab DJ, McKerrow JH. PMID: 18820745.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    8. A parasite cysteine protease is key to host protein degradation and iron acquisition. J Biol Chem. 2008 Oct 24; 283(43):28934-43. O'Brien TC, Mackey ZB, Fetter RD, Choe Y, O'Donoghue AJ, Zhou M, Craik CS, Caffrey CR, McKerrow JH. PMID: 18701454.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    9. Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. J Med Chem. 2008 Feb 14; 51(3):545-52. Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. PMID: 18173229.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    10. Genetic composition of the Bacillus subtilis SOS system. J Bacteriol. 2005 Nov; 187(22):7655-66. Au N, Kuester-Schoeck E, Mandava V, Bothwell LE, Canny SP, Chachu K, Colavito SA, Fuller SN, Groban ES, Hensley LA, O'Brien TC, Shah A, Tierney JT, Tomm LL, O'Gara TM, Goranov AI, Grossman AD, Lovett CM. PMID: 16267290; PMCID: PMC1280312.
      View in: PubMed   Mentions: 70     Fields:    Translation:Cells
    11. A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei. J Biol Chem. 2004 Nov 12; 279(46):48426-33. Mackey ZB, O'Brien TC, Greenbaum DC, Blank RB, McKerrow JH. PMID: 15326171.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    12. Synthesis of 4-hydroxysphinganine and characterization of sphinganine hydroxylase activity in corn. Arch Biochem Biophys. 2003 Jul 15; 415(2):184-92. Wright BS, Snow JW, O'Brien TC, Lynch DV. PMID: 12831841.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
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