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A new data effort to inform career choices in biomedicine. Science. 2017 Dec 15; 358(6369):1388-1389.
Blank R, Daniels RJ, Gilliland G, Gutmann A, Hawgood S, Hrabowski FA, Pollack ME, Price V, Reif LR, Schlissel MS. PMID: 29242335.
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PubMed Mentions:
20 Fields:
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Innate immunity of surfactant proteins A and D in urinary tract infection with uropathogenic Escherichia coli. Innate Immun. 2016 Jan; 22(1):9-20.
Hu F, Ding G, Zhang Z, Gatto LA, Hawgood S, Poulain FR, Cooney RN, Wang G. PMID: 26511057; PMCID: PMC4679646.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Protective Role of Surfactant Protein D in Ocular Staphylococcus aureus Infection. PLoS One. 2015; 10(9):e0138597.
Zhang Z, Abdel-Razek O, Hawgood S, Wang G. PMID: 26398197; PMCID: PMC4580580.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Precision medicine: Beyond the inflection point. Sci Transl Med. 2015 Aug 12; 7(300):300ps17.
Hawgood S, Hook-Barnard IG, O'Brien TC, Yamamoto KR. PMID: 26268311.
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PubMed Mentions:
44 Fields:
Translation:
Humans
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Commentary: Team science. Acad Med. 2013 Feb; 88(2):156-7.
O'Brien T, Yamamoto K, Hawgood S. PMID: 23361027.
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PubMed Mentions:
4 Fields:
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Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes. Endocrinology. 2013 Jan; 154(1):483-98.
Montalbano AP, Hawgood S, Mendelson CR. PMID: 23183169; PMCID: PMC3529364.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia. PLoS One. 2012; 7(4):e35066.
Stidsen JV, Khorooshi R, Rahbek MK, Kirketerp-Møller KL, Hansen PB, Bie P, Kejling K, Mandrup S, Hawgood S, Nielsen O, Nielsen CH, Owens T, Holmskov U, Sørensen GL. PMID: 22509382; PMCID: PMC3324408.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Congenital diaphragmatic hernia: endothelin-1, pulmonary hypertension, and disease severity. Am J Respir Crit Care Med. 2010 Aug 15; 182(4):555-61.
Keller RL, Tacy TA, Hendricks-Munoz K, Xu J, Moon-Grady AJ, Neuhaus J, Moore P, Nobuhara KK, Hawgood S, Fineman JR. PMID: 20413632; PMCID: PMC2937245.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis. Mol Immunol. 2010 Jun; 47(10):1923-30.
Madan T, Reid KB, Clark H, Singh M, Nayak A, Sarma PU, Hawgood S, Kishore U. PMID: 20413160.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
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Clearance of Pseudomonas aeruginosa from a healthy ocular surface involves surfactant protein D and is compromised by bacterial elastase in a murine null-infection model. Infect Immun. 2009 Jun; 77(6):2392-8.
Mun JJ, Tam C, Kowbel D, Hawgood S, Barnett MJ, Evans DJ, Fleiszig SM. PMID: 19349424; PMCID: PMC2687330.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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A recombinant fragment of human surfactant protein D lacking the short collagen-like stalk fails to correct morphological alterations in lungs of SP-D deficient mice. Anat Rec (Hoboken). 2009 Feb; 292(2):183-9.
Knudsen L, Wucherpfennig K, Mackay RM, Townsend P, Mühlfeld C, Richter J, Hawgood S, Reid K, Clark H, Ochs M. PMID: 19177340.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice. Am J Physiol Lung Cell Mol Physiol. 2009 Feb; 296(2):L167-75.
Gram K, Yang S, Steiner M, Somani A, Hawgood S, Blazar BR, Panoskaltsis-Mortari A, Haddad IY. PMID: 18996902; PMCID: PMC2643990.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa. FEMS Immunol Med Microbiol. 2008 Nov; 54(2):177-84.
Ni M, Tam C, Verma A, Ramphal R, Hawgood S, Evans DJ, Fleiszig SM. PMID: 18657106.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Genetic analysis of congenital cystic adenomatoid malformation reveals a novel pulmonary gene: fatty acid binding protein-7 (brain type). Pediatr Res. 2008 Jul; 64(1):11-6.
Wagner AJ, Stumbaugh A, Tigue Z, Edmondson J, Paquet AC, Farmer DL, Hawgood S. PMID: 18391847.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Laser microdissection allows detection of abnormal gene expression in cystic adenomatoid malformation of the lung. J Pediatr Surg. 2008 Jun; 43(6):1044-51.
Jancelewicz T, Nobuhara K, Hawgood S. PMID: 18558180.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice. Respir Res. 2007 Oct 03; 8:70.
Knudsen L, Ochs M, Mackay R, Townsend P, Deb R, Mühlfeld C, Richter J, Gilbert F, Hawgood S, Reid K, Clark H. PMID: 17915009; PMCID: PMC2078589.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1. Am J Respir Cell Mol Biol. 2007 Dec; 37(6):651-9.
Koth LL, Alex B, Hawgood S, Nead MA, Sheppard D, Erle DJ, Morris DG. PMID: 17641300; PMCID: PMC2219547.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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N-linked glycosylation attenuates H3N2 influenza viruses. J Virol. 2007 Aug; 81(16):8593-600.
Vigerust DJ, Ulett KB, Boyd KL, Madsen J, Hawgood S, McCullers JA. PMID: 17553891; PMCID: PMC1951338.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Helicobacter infection in the surfactant protein D-deficient mouse. Helicobacter. 2007 Apr; 12(2):112-23.
Khamri W, Worku ML, Anderson AE, Walker MM, Hawgood S, Reid KB, Clark HW, Thursz MR. PMID: 17309747.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicol Appl Pharmacol. 2007 Apr 01; 220(1):72-82.
Haque R, Umstead TM, Ponnuru P, Guo X, Hawgood S, Phelps DS, Floros J. PMID: 17307210; PMCID: PMC1906716.
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PubMed Mentions:
48 Fields:
Translation:
Animals
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Abnormal vascular tone in infants and children with lung hypoplasia: Findings from cardiac catheterization and the response to chronic therapy. Pediatr Crit Care Med. 2006 Nov; 7(6):589-94.
Keller RL, Moore P, Teitel D, Hawgood S, McQuitty J, Fineman JR. PMID: 17006391.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Deletion of the transmembrane transporter ABCG1 results in progressive pulmonary lipidosis. J Biol Chem. 2006 Sep 29; 281(39):29401-10.
Baldán A, Tarr P, Vales CS, Frank J, Shimotake TK, Hawgood S, Edwards PA. PMID: 16887795.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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IL-4 and IL-13 form a negative feedback circuit with surfactant protein-D in the allergic airway response. J Immunol. 2006 Mar 15; 176(6):3557-65.
Haczku A, Cao Y, Vass G, Kierstein S, Nath P, Atochina-Vasserman EN, Scanlon ST, Li L, Griswold DE, Chung KF, Poulain FR, Hawgood S, Beers MF, Crouch EC. PMID: 16517724.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Surfactant proteins A and D enhance pulmonary clearance of Pseudomonas aeruginosa. Am J Respir Cell Mol Biol. 2006 Jun; 34(6):704-10.
Giannoni E, Sawa T, Allen L, Wiener-Kronish J, Hawgood S. PMID: 16456184; PMCID: PMC2644232.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Surfactant protein D is proatherogenic in mice. Am J Physiol Heart Circ Physiol. 2006 Jun; 290(6):H2286-94.
Sorensen GL, Madsen J, Kejling K, Tornoe I, Nielsen O, Townsend P, Poulain F, Nielsen CH, Reid KB, Hawgood S, Falk E, Holmskov U. PMID: 16387789.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Mast cells protect mice from Mycoplasma pneumonia. Am J Respir Crit Care Med. 2006 Jan 15; 173(2):219-25.
Xu X, Zhang D, Lyubynska N, Wolters PJ, Killeen NP, Baluk P, McDonald DM, Hawgood S, Caughey GH. PMID: 16210667; PMCID: PMC2662990.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Design-based stereological analysis of the lung parenchymal architecture and alveolar type II cells in surfactant protein A and D double deficient mice. Anat Rec A Discov Mol Cell Evol Biol. 2005 Oct; 286(2):885-90.
Jung A, Allen L, Nyengaard JR, Gundersen HJ, Richter J, Hawgood S, Ochs M. PMID: 16086431.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Alveolar surfactant protein D content modulates bleomycin-induced lung injury. Am J Respir Crit Care Med. 2005 Oct 01; 172(7):869-77.
Casey J, Kaplan J, Atochina-Vasserman EN, Gow AJ, Kadire H, Tomer Y, Fisher JH, Hawgood S, Savani RC, Beers MF. PMID: 15994463; PMCID: PMC2718404.
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PubMed Mentions:
33 Fields:
Translation:
Animals
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Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation. J Immunol. 2005 Jun 01; 174(11):7352-8.
Palaniyar N, Clark H, Nadesalingam J, Shih MJ, Hawgood S, Reid KB. PMID: 15905582.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa. Infect Immun. 2005 Apr; 73(4):2147-56.
Ni M, Evans DJ, Hawgood S, Anders EM, Sack RA, Fleiszig SM. PMID: 15784557; PMCID: PMC1087391.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species. Infect Immun. 2004 Oct; 72(10):6002-11.
Atochina EN, Beck JM, Preston AM, Haczku A, Tomer Y, Scanlon ST, Fusaro T, Casey J, Hawgood S, Gow AJ, Beers MF. PMID: 15385504; PMCID: PMC517574.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimals
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Infant pulmonary function in a randomized trial of fetal tracheal occlusion for severe congenital diaphragmatic hernia. Pediatr Res. 2004 Nov; 56(5):818-25.
Keller RL, Hawgood S, Neuhaus JM, Farmer DL, Lee H, Albanese CT, Harrison MR, Kitterman JA. PMID: 15319458.
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PubMed Mentions:
7 Fields:
Translation:
HumansCTClinical Trials
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GM-CSF mediates alveolar epithelial type II cell changes, but not emphysema-like pathology, in SP-D-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2004 Dec; 287(6):L1333-41.
Ochs M, Knudsen L, Allen L, Stumbaugh A, Levitt S, Nyengaard JR, Hawgood S. PMID: 15310555.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Pulmonary collectins modulate strain-specific influenza a virus infection and host responses. J Virol. 2004 Aug; 78(16):8565-72.
Hawgood S, Brown C, Edmondson J, Stumbaugh A, Allen L, Goerke J, Clark H, Poulain F. PMID: 15280465; PMCID: PMC479098.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Surfactant protein B: structure and function. Biol Neonate. 2004; 85(4):285-9.
Hawgood S. PMID: 15218284.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Delayed clearance of pneumocystis carinii infection, increased inflammation, and altered nitric oxide metabolism in lungs of surfactant protein-D knockout mice. J Infect Dis. 2004 Apr 15; 189(8):1528-39.
Atochina EN, Gow AJ, Beck JM, Haczku A, Inch A, Kadire H, Tomer Y, Davis C, Preston AM, Poulain F, Hawgood S, Beers MF. PMID: 15073692.
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PubMed Mentions:
35 Fields:
Translation:
Animals
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Treatment of rebound and chronic pulmonary hypertension with oral sildenafil in an infant with congenital diaphragmatic hernia. Pediatr Crit Care Med. 2004 Mar; 5(2):184-7.
Keller RL, Hamrick SE, Kitterman JA, Fineman JR, Hawgood S. PMID: 14987351.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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A recombinant fragment of human surfactant protein D reduces alveolar macrophage apoptosis and pro-inflammatory cytokines in mice developing pulmonary emphysema. Ann N Y Acad Sci. 2003 Dec; 1010:113-6.
Clark H, Palaniyar N, Hawgood S, Reid KB. PMID: 15033705.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Surfactant protein D binds genomic DNA and apoptotic cells, and enhances their clearance, in vivo. Ann N Y Acad Sci. 2003 Dec; 1010:471-5.
Palaniyar N, Clark H, Nadesalingam J, Hawgood S, Reid KB. PMID: 15033772.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic hernia. N Engl J Med. 2003 Nov 13; 349(20):1916-24.
Harrison MR, Keller RL, Hawgood SB, Kitterman JA, Sandberg PL, Farmer DL, Lee H, Filly RA, Farrell JA, Albanese CT. PMID: 14614166.
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PubMed Mentions:
83 Fields:
Translation:
HumansCTClinical Trials
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Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung. J Biol Chem. 2003 Dec 05; 278(49):49006-14.
Brasch F, Ochs M, Kahne T, Guttentag S, Schauer-Vukasinovic V, Derrick M, Johnen G, Kapp N, Muller KM, Richter J, Giller T, Hawgood S, Buhling F. PMID: 13129928.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Surfactant protein B in type II pneumocytes and intra-alveolar surfactant forms of human lungs. Am J Respir Cell Mol Biol. 2004 Apr; 30(4):449-58.
Brasch F, Johnen G, Winn-Brasch A, Guttentag SH, Schmiedl A, Kapp N, Suzuki Y, Müller KM, Richter J, Hawgood S, Ochs M. PMID: 12972403.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Surfactant protein-D, a mediator of innate lung immunity, alters the products of nitric oxide metabolism. Am J Respir Cell Mol Biol. 2004 Mar; 30(3):271-9.
Atochina EN, Beers MF, Hawgood S, Poulain F, Davis C, Fusaro T, Gow AJ. PMID: 12871850.
View in:
PubMed Mentions:
28 Fields:
Translation:
Animals
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Neurodevelopmental outcome of infants supported with extracorporeal membrane oxygenation after cardiac surgery. Pediatrics. 2003 Jun; 111(6 Pt 1):e671-5.
Hamrick SE, Gremmels DB, Keet CA, Leonard CH, Connell JK, Hawgood S, Piecuch RE. PMID: 12777584.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L602-10.
Haddad IY, Milla C, Yang S, Panoskaltsis-Mortari A, Hawgood S, Lacey DL, Blazar BR. PMID: 12740217.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Resolution of hydrops fetalis in congenital cystic adenomatoid malformation after prenatal steroid therapy. J Pediatr Surg. 2003 Mar; 38(3):508-10.
Tsao K, Hawgood S, Vu L, Hirose S, Sydorak R, Albanese CT, Farmer DL, Harrison MR, Lee H. PMID: 12632377.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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MR imaging of hepatic pulmonary fusion in neonates. AJR Am J Roentgenol. 2003 Feb; 180(2):438-40.
Keller RL, Aaroz PA, Hawgood S, Higgins CB. PMID: 12540449.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues. Am J Physiol Lung Cell Mol Physiol. 2003 May; 284(5):L759-65.
Jain D, Dodia C, Bates SR, Hawgood S, Poulain FR, Fisher AB. PMID: 12676766.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema. Am J Physiol Lung Cell Mol Physiol. 2002 Nov; 283(5):L1002-10.
Hawgood S, Ochs M, Jung A, Akiyama J, Allen L, Brown C, Edmondson J, Levitt S, Carlson E, Gillespie AM, Villar A, Epstein CJ, Poulain FR. PMID: 12376353.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Surfactant protein D reduces alveolar macrophage apoptosis in vivo. J Immunol. 2002 Sep 15; 169(6):2892-9.
Clark H, Palaniyar N, Strong P, Edmondson J, Hawgood S, Reid KB. PMID: 12218102.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Surfactant protein A decreases lung injury and mortality after murine marrow transplantation. Am J Respir Cell Mol Biol. 2002 Sep; 27(3):297-305.
Yang S, Milla C, Panoskaltsis-Mortari A, Hawgood S, Blazar BR, Haddad IY. PMID: 12204891.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Tissue distribution of surfactant proteins A and D in the mouse. J Histochem Cytochem. 2002 Jul; 50(7):993-6.
Akiyama J, Hoffman A, Brown C, Allen L, Edmondson J, Poulain F, Hawgood S. PMID: 12070278.
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PubMed Mentions:
40 Fields:
Translation:
Animals
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Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus. Am J Respir Cell Mol Biol. 2002 Mar; 26(3):277-82.
Li G, Siddiqui J, Hendry M, Akiyama J, Edmondson J, Brown C, Allen L, Levitt S, Poulain F, Hawgood S. PMID: 11867335.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Intracellular and intraalveolar localization of surfactant protein A (SP-A) in the parenchymal region of the human lung. Am J Respir Cell Mol Biol. 2002 Jan; 26(1):91-8.
Ochs M, Johnen G, Müller KM, Wahlers T, Hawgood S, Richter J, Brasch F. PMID: 11751208.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells