Xiaoxin Chen, PhD

Photo of Xiaoxin Chen, PhD
Title(s)Associate Specialist, Cardiovascular Research Inst
SchoolSchool of Medicine
AddressSan Francisco CA 94158
PronounsHe/She
ORCID ORCID Icon0000-0003-3092-7010 Additional info
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    The University of Hong KongPhD08/2018Chinese Medicine
    Xiamen UniversityMsc07/2014Biochemistry and molecular biology

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chromatin topology control by a muscle-specific ribosomal protein. bioRxiv. 2026. Makoto Nakamura, Xiaoxin Chen, Shun Yao, Lynette Xin Chan, Ruan Hongmei, Alexis Boulinguiez, Nav Lally, Hao Wu, Kara Kodani, Kentaro Hirose, James Pirruccello, Alberto Malerba, Yifan Cheng, Vasanth Vedantham, Longzhi Tan, Jeffrey E. Olgin, Di Lang, Guo N. Huang. View Publication.
    2. Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko. NPJ Regen Med. 2026 Apr 15; 11(1). Jacyniak K, Williams CJA, Beaufrère H, Simpson J, Huang GN, Chen X, Vickaryous MK. PMID: 41986369; PMCID: PMC13190692.
      View in: PubMed   Mentions:
    3. A transcription regulator atlas identifies TOX3 as an Atoh1 coactivator in cerebellar development and tumorigenesis. Proc Natl Acad Sci U S A. 2026 Mar 24; 123(12):e2527163123. Chen X, Zhong X, Yue W, Wang B, Woo B, Goodarzi H, Luo Z, Lu QR, Flamant F, Reiter JF, Huang GN. PMID: 41849381; PMCID: PMC13012119.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. CAR macrophages with built-In CD47 blocker combat tumor antigen heterogeneity and activate T cells via cross-presentation. Nat Commun. 2025 Apr 30; 16(1):4069. Chen S, Wang Y, Dang J, Song N, Chen X, Wang J, Huang GN, Brown CE, Yu J, Weissman IL, Rosen ST, Feng M. PMID: 40307254; PMCID: PMC12043996.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    5. Heart regeneration from the whole-organism perspective to single-cell resolution. NPJ Regen Med. 2024 Nov 15; 9(1):34. Chen X, Zhong X, Huang GN. PMID: 39548113; PMCID: PMC11568173.
      View in: PubMed   Mentions: 5  
    6. 1H Nuclear Magnetic Resonance-Based Metabolomic Profiling and Comparison of Human Milk across Different Lactation Stages in Secretors and Nonsecretors: A Study of Chinese Lactating Women. J Nutr. 2025 01; 155(1):78-86. Chen G, Chen L, Wang H, Zhang J, Sun X, Chen X, Fan J, Jia Z, Huang Y. PMID: 39491676.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. An injury-responsive mmp14b enhancer is required for heart regeneration. Sci Adv. 2023 12; 9(48):eadh5313. Zlatanova I, Sun F, Wu RS, Chen X, Lau BH, Colombier P, Sinha T, Celona B, Xu SM, Materna SC, Huang GN, Black BL. PMID: 38019918; PMCID: PMC10686572.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    8. Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19. Elife. 2023 10 13; 12. COVID Tissue Atlas Consortium, Granados AA, Bucher S, Song H, Agrawal A, Chen AT, Peng T, Neff N, Pisco AO, Huang F, Wang B. PMID: 37830426; PMCID: PMC10575628.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Punicalagin as a novel tyrosinase and melanin inhibitor: Inhibitory activity and mechanism. LWT. 2022; 161. Zi-Yi Yu, Ke Xu, Xuan Wang, Yi-Ting Wen, Lin-Jun Wang, De-Qiang Huang, Xiao-Xin Chen, Wei-Ming Chai. View Publication.
    10. Granatin B and punicalagin from Chinese herbal medicine pomegranate peels elicit reactive oxygen species-mediated apoptosis and cell cycle arrest in colorectal cancer cells. Phytomedicine. 2022 Mar; 97:153923. Chen XX, Khyeam S, Zhang ZJ, Zhang KY. PMID: 35026619.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    11. Adrenergic-Thyroid Hormone Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity. Circulation. 2021 09 21; 144(12):1000-1003. Payumo AY, Chen X, Hirose K, Chen X, Hoang A, Khyeam S, Yu H, Wang J, Chen Q, Powers N, Chen L, Bigley RB, Lovas J, Hu G, Huang GN. PMID: 34543065; PMCID: PMC8457303.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    12. Evidence for Edible Chinese Herbal Medicine as an Alternative Approach for the Treatment of Colorectal Cancer. Clinical Oncology and Research. 2020. Xiaoxin Chen, Hei Wan, Kar-Ho Lam, Hai-Yong Chen, Yi-Bin Feng, Calvin Kai-Fai Lee, Sonny Hing-Min Tse, Ling-Min Tian, Xiang Lin, Wei Meng, Min-Yi Tian, Jing Su, George Pak-Heng Leung, Zhang-Jin Zhang, Sydney Chi-Wai Tang, Kalin Yan-Bo ZHANG. View Publication.
    13. Loss of a novel striated muscle-enriched mitochondrial protein Coq10a enhances postnatal cardiac hypertrophic growth. bioRxiv. 2019. Kentaro Hirose, Steven Chang, Hongyao Yu, Jiajia Wang, Emanuele Barca, Xiaoxin Chen, Sheamin Khyeam, Kazuki Tajima, Takeshi Yoneshiro, Shingo Kajimura, Catarina M. Quinzii, Guang Hu, Guo N. Huang. View Publication.
    14. Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer's Disease Models In vitro and In vivo. Neuroscience. 2018 12 01; 394:72-82. Liu JY, Chen XX, Chen HY, Shi J, Leung GP, Tang SC, Lao LX, Yip HK, Lee KF, Sze SC, Zhang ZJ, Zhang KY. PMID: 30266683.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    15. Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction. J Agric Food Chem. 2018 Jul 11; 66(27):7054-7064. Chen XX, Lam KK, Feng YB, Xu K, Sze SC, Tang SC, Leung GP, Lee CK, Shi J, Yang ZJ, Li ST, Zhang ZJ, Zhang KY. PMID: 29920075.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. Dendrobine targeting JNK stress signaling to sensitize chemotoxicity of cisplatin against non-small cell lung cancer cells in vitro and in vivo. Phytomedicine. 2019 Feb; 53:18-27. Song TH, Chen XX, Lee CK, Sze SC, Feng YB, Yang ZJ, Chen HY, Li ST, Zhang LY, Wei G, Shi J, Xu K, Ng TB, Zhu LL, Zhang KY. PMID: 30668397.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    17. Combined Therapy of Traditional Chinese and Western Medicine to Treat Non-Small-Cell Lung Cancer: A Review. Traditional Chinese Medicine. 2018; 7:142-146. Yip Chun-Wang, Man Hei-Yi, Chan Lap-Yee, Lam Kar-Ho, Chen Xiao-Xin, Tian-He Song, Cho-Wing Sze; Zhangjin Zhang, Zhang Yanbo. View Publication.
    18. Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats. Food Chem Toxicol. 2017 Dec; 110:49-61. Chen XX, Lam KH, Chen QX, Leung GP, Tang SCW, Sze SC, Xiao JB, Feng F, Wang Y, Zhang KY, Zhang ZJ. PMID: 29030256.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    19. Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil. Food Chem Toxicol. 2017; 107:248-260. Xiao-Xin Chen, George Pak-Heng Leung, Zhang-Jin Zhang, Jian-Bo Xiao, Li-Xing Lao, Feng Feng, Judith Choi-Wo Mak, Ying Wang, Stephen Cho-Wing Sze, Kalin Yan-Bo Zhang. View Publication.
    20. Chinese medicines in the treatment of experimental diabetic nephropathy. Chin Med. 2016; 11:6. Liu JY, Chen XX, Tang SC, Sze SC, Feng YB, Lee KF, Zhang KY. PMID: 26913057; PMCID: PMC4765093.
      View in: PubMed   Mentions: 3  
    21. Quality and safety control of tumor-shrinking decoction (TSD): A Chinese herbal preparation for the treatment of uterine fibroids. Biotechnol Appl Biochem. 2017 Jan; 64(1):126-133. Chen XX, Lin WL, Yeung WF, Song TH, Lao LX, Zhang YB, Meng W. PMID: 26601793.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    22. Dendrobium officinale polysaccharides ameliorated pulmonary function while inhibiting mucin-5AC and stimulating aquaporin-5 expression. J Funct Foods. 2016; 21:359-371. Tian-He Song, Xiao-Xin Chen, Sydney Chi Wai Tang, James Chung Man Ho, Li-Xing Lao, Tzi Bun Ng, Kai-Fai Lee, Stephen Cho Wing Sze, Kalin Yanbo Zhang. View Publication.
    23. The research of the reference value of urinary mercury for 0-6 years old children in coast area. Chinese Journal of Women and Children Health. 2015; 6(3):52-55. Chen Gui-Xia, Chen Xiao-Xin, Yan Chong-Huai, Zeng Guo-Zhang, Zhang Ji-Yong, Shi Jun-Xia, Wu Xing-Dong . View Publication.
    24. Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy. J Funct Foods. 2015; 14:12-22. Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Kalin Yan-Bo Zhang. View Publication.
    25. Surveying mercury levels in hair, blood and urine of under 7-year old children from a coastal city in China. Int J Environ Res Public Health. 2014 Nov 20; 11(11):12029-41. Chen G, Chen X, Yan C, Wu X, Zeng G. PMID: 25419876; PMCID: PMC4245658.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    26. Antioxidant and antityrosinase proanthocyanidins from Polyalthia longifolia leaves. J Biosci Bioeng. 2014 Nov; 118(5):583-7. Chen XX, Liang G, Chai WM, Feng HL, Zhou HT, Shi Y, Chen QX. PMID: 24863181.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    27. Isolation and purification of condensed tannins from flamboyant tree and their antioxidant and antityrosinase activities. Appl Biochem Biotechnol. 2014 May; 173(1):179-92. Feng HL, Tian L, Chai WM, Chen XX, Shi Y, Gao YS, Yan CL, Chen QX. PMID: 24671565.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. Condensed tannins from Ficus virens as tyrosinase inhibitors: structure, inhibitory activity and molecular mechanism. PLoS One. 2014; 9(3):e91809. Chen XX, Shi Y, Chai WM, Feng HL, Zhuang JX, Chen QX. PMID: 24637701; PMCID: PMC3956756.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    29. Structure characterization of proanthocyanidins from Caryota ochlandra Hance and their bioactivities. Food Chem. 2014 Jul 15; 155:1-8. Chen XX, Feng HL, Ding YM, Chai WM, Xiang ZH, Shi Y, Chen QX. PMID: 24594146.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    30. Progress on molecular mechanism of mercury induced neurotoxicity in children. Int J Pediatrics (ISSN 1673-4408). 2013; 40:489−492. Chen Gui-Xia, Chen Xiao-Xin, Li Jian. View Publication.
    31. Reversible and competitive inhibitory kinetics of amoxicillin on mushroom tyrosinase. Int J Biol Macromol. 2013 Nov; 62:726-33. Chen XX, Zhang J, Chai WM, Feng HL, Xiang ZH, Shen DY, Chen QX. PMID: 24099941.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    32. Optimization of extraction of phenolics from leaves of Ficus virens. J Zhejiang Univ Sci B. 2013 Oct; 14(10):903-15. Chen XX, Wu XB, Chai WM, Feng HL, Shi Y, Zhou HT, Chen QX. PMID: 24101207; PMCID: PMC3796642.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
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