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Guo Huang, PhD

Title(s)Associate Professor, Cardiovascular Research Inst
SchoolSchool of Medicine
Address555 Mission Bay Blvd South
San Francisco CA 94158
Phone415-502-2879
ORCID ORCID Icon0000-0002-4335-9123 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    American Heart Association2020Transformational Project Award
    Department of Defense2019Discovery Award
    UCSF2018Program for Breakthrough Biomedical Research
    UCSF2017Independence Award
    American Federation for Aging Research2016  - 2018AFAR Junior Faculty Grant
    March of Dimes Foundation2016  - 2018Basil O'Connor Starter Award
    American Heart Association2016  - 2018AHA Career Beginning Grant-in-aid Award
    UCSF2015Academic Senator Award
    UCSF2014  - 2015Program for Breakthrough Biomedical Research
    Edward Mallinckrodt Jr. Foundation2014  - 2017Mallinckrodt Young Investigaor Grants
    LSRF2014  - 2014O'Donnell Foundation Fund
    NIH/NHBLI2012  - 2017NIH Pathway to Independence Award (K99/R00)
    LSRF2009  - 2012Life Sciences Research Foundation Fellowship

    Collapse Overview 
    Collapse Overview
    B.S. Peking University (summa cum laude)
    Ph.D. Johns Hopkins Medical Institute (Phi Beta Kappa)
    Postdoc. UT Southwestern Medical Center (Life Sciences Research Foundation Fellow)

    Collapse Research 
    Collapse Research Activities and Funding
    Molecular control of cardiac regenerative potential
    NIH R01HL138456Dec 1, 2017 - Nov 30, 2022
    Role: Principal Investigator
    Retinoic Acid Signaling in Heart Development and Regeneration
    NIH/NHBLI R00HL114738Mar 1, 2014 - Feb 28, 2018
    Role: Principal Investigator
    Retinoic Acid Signaling in Heart Development and Regeneration
    NIH K99HL114738Aug 15, 2012 - Dec 10, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse In The News
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice. JCI Insight. 2020 Nov 05; 5(21). Wong JC, Perez-Mancera PA, Huang TQ, Kim J, Grego-Bessa J, Del Pilar Alzamora M, Kogan SC, Sharir A, Keefe SH, Morales CE, Schanze D, Castel P, Hirose K, Huang GN, Zenker M, Sheppard D, Klein OD, Tuveson DA, Braun BS, Shannon K. PMID: 32990679.
      View in: PubMed   Mentions:    Fields:    
    2. In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential. J Mol Cell Cardiol. 2020 05; 142:126-134. Cutie S, Payumo AY, Lunn D, Huang GN. PMID: 32289320.
      View in: PubMed   Mentions:    Fields:    
    3. Lamin B2, Guardian of Cardiomyocyte Nuclear Division. Dev Cell. 2020 04 06; 53(1):5-7. Payumo AY, Huang GN. PMID: 32259493.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Defined factors to reactivate cell cycle activity in adult mouse cardiomyocytes. Sci Rep. 2019 12 11; 9(1):18830. Judd J, Lovas J, Huang GN. PMID: 31827131.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Evidence for hormonal control of heart regenerative capacity during endothermy acquisition. Science. 2019 04 12; 364(6436):184-188. Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, Field KA, Reeder DM, Maden M, Yartsev MM, Wolfgang MJ, Grützner F, Scanlan TS, Szweda LI, Buffenstein R, Hu G, Flamant F, Olgin JE, Huang GN. PMID: 30846611.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    6. Unconventional Functions of Muscles in Planarian Regeneration. Dev Cell. 2017 12 18; 43(6):657-658. Cutie S, Hoang AT, Payumo AY, Huang GN. PMID: 29257948.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Insights into nuclear dynamics using live-cell imaging approaches. Wiley Interdiscip Rev Syst Biol Med. 2017 03; 9(2). PMID: 28078793.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    8. Isolation, Culture and Transduction of Adult Mouse Cardiomyocytes. J Vis Exp. 2016 Aug 28; (114). PMID: 27685811.
      View in: PubMed   Mentions: 6     Fields:    
    9. C/EBP transcription factors mediate epicardial activation during heart development and injury. Science. 2012 Dec 21; 338(6114):1599-603. PMID: 23160954.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    10. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature. 2012 May 13; 485(7400):599-604. PMID: 22660318.
      View in: PubMed   Mentions: 436     Fields:    Translation:AnimalsCells
    11. T Cell Calcium Mobilization Study (Flow Cytometry). Bio Protoc. 2012 May 05; 2(9). Huang GN. PMID: 29552583.
      View in: PubMed   Mentions:
    12. Biotinylation of Cell Surface Proteins. Bio Protoc. 2012 May 05; 2(9). Huang GN. PMID: 29552582.
      View in: PubMed   Mentions:
    13. Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. Neuron. 2009 Nov 25; 64(4):471-83. Shim S, Yuan JP, Kim JY, Zeng W, Huang G, Milshteyn A, Kern D, Muallem S, Ming GL, Worley PF. PMID: 19945390.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    14. STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction. Mol Cell. 2008 Nov 07; 32(3):439-48. Zeng W, Yuan JP, Kim MS, Choi YJ, Huang GN, Worley PF, Muallem S. PMID: 18995841.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    15. NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science. 2008 Jan 25; 319(5862):476-81. Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF. PMID: 18218901.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    16. STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol. 2007 Jun; 9(6):636-45. Yuan JP, Zeng W, Huang GN, Worley PF, Muallem S. PMID: 17486119.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansCells
    17. STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol. 2006 Sep; 8(9):1003-10. Huang GN, Zeng W, Kim JY, Yuan JP, Han L, Muallem S, Worley PF. PMID: 16906149.
      View in: PubMed   Mentions: 270     Fields:    Translation:HumansCells
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