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    Ben Cheyette

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    Address1550 4th Street, Bldg 19B
    San Francisco CA 94158
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      Collapse Biography 
      Collapse Education and Training
      University of California Los AngelesM.D.School of Medicine1994
      Collapse Awards and Honors
      Princeton University1988Charles M. Cannon Prize for Research Achievement
      Princeton University1988Sigma Xi National Scientific Honor Society
      Princeton University1988Magna Cum Laude, Biology
      UCLA School of Medicine1995Emil Bogen Prize for Outstanding Research Achievement
      National Institute of Mental Health1997Special Achievement as a Resident in Psychiatry
      American Psychiatric Association1998Excellence in Psychiatry Residency
      University of Washington, Psychiatry1999Academic Excellence
      University of Washington (UW)1999 - 2001NARSAD Young Investigator Award
      UW & University of California, San Francisco2001 - 2003NARSAD Young Investigator Award
      UCSF2014 - 2016NARSAD Independent Investigator Award

      Collapse ORNG Applications 
      Collapse Websites
      Collapse In The News
      Collapse NIH Awarded Grants

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Yang X, Fisher DA, Cheyette BN. SEC14 and Spectrin Domains 1 (Sestd1), Dishevelled 2 (Dvl2) and Dapper Antagonist of Catenin-1 (Dact1) co-regulate the Wnt/Planar Cell Polarity (PCP) pathway during mammalian development. Commun Integr Biol. 2013 Nov 1; 6(6):e26834.
        View in: PubMed PMC3914910
      2. Arguello A, Cheyette BN. Dapper Antagonist of Catenin-1 (Dact1) contributes to dendrite arborization in forebrain cortical interneurons. Commun Integr Biol. 2013 Nov 1; 6(6):e26656.
        View in: PubMed PMC3925456
      3. Martin PM, Yang X, Robin N, Lam E, Rabinowitz JS, Erdman CA, Quinn J, Weiss LA, Hamilton SP, Kwok PY, Moon RT, Cheyette BN. A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation. Transl Psychiatry. 2013; 3:e301.
        View in: PubMed PMC3784764
      4. Arguello A, Yang X, Vogt D, Stanco A, Rubenstein JL, Cheyette BN. Dapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneurons. PLoS One. 2013; 8(6):e67679.
        View in: PubMed PMC3691262
      5. Yang X, Cheyette BN. SEC14 and spectrin domains 1 (Sestd1) and Dapper antagonist of catenin 1 (Dact1) scaffold proteins cooperatively regulate the Van Gogh-like 2 (Vangl2) four-pass transmembrane protein and planar cell polarity (PCP) pathway during embryonic development in mice. J Biol Chem. 2013 Jul 12; 288(28):20111-20.
        View in: PubMed PMC3711279
      6. Mulligan KA, Cheyette BN. Wnt signaling in vertebrate neural development and function. J Neuroimmune Pharmacol. 2012 Dec; 7(4):774-87.
        View in: PubMed PMC3518582
      7. Kivimäe S, Martin PM, Kapfhamer D, Ruan Y, Heberlein U, Rubenstein JL, Cheyette BN. Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1. Transl Psychiatry. 2011; 1:e43.
        View in: PubMed PMC3309484
      8. Kivimäe S, Yang XY, Cheyette BN. All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. BMC Biochem. 2011; 12:33.
        View in: PubMed PMC3141656
      9. Okerlund ND, Cheyette BN. Synaptic Wnt signaling-a contributor to major psychiatric disorders? J Neurodev Disord. 2011 Jun; 3(2):162-74.
        View in: PubMed PMC3180925
      10. Okerlund ND, Kivimäe S, Tong CK, Peng IF, Ullian EM, Cheyette BN. Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain. J Neurosci. 2010 Mar 24; 30(12):4362-8.
        View in: PubMed PMC2848693
      11. Kettunen P, Kivimäe S, Keshari P, Klein OD, Cheyette BN, Luukko K. Dact1-3 mRNAs exhibit distinct expression domains during tooth development. Gene Expr Patterns. 2010 Feb-Mar; 10(2-3):140-3.
        View in: PubMed PMC2849867
      12. Suriben R, Kivimäe S, Fisher DA, Moon RT, Cheyette BN. Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. Nat Genet. 2009 Sep; 41(9):977-85.
        View in: PubMed PMC2733921
      13. Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN. Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1. PLoS One. 2009; 4(2):e4310.
        View in: PubMed PMC2629544
      14. Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK. Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network. Diabetes. 2009 Mar; 58(3):609-19.
        View in: PubMed PMC2646059
      15. Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q. DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell. 2008 Jun; 13(6):529-41.
        View in: PubMed PMC2577847
      16. Cheyette BN, Cheyette SN, Cusmano-Ozog K, Enns GM. Dopa-responsive dystonia presenting as delayed and awkward gait. Pediatr Neurol. 2008 Apr; 38(4):273-5.
        View in: PubMed
      17. Suriben R, Fisher DA, Cheyette BN. Dact1 presomitic mesoderm expression oscillates in phase with Axin2 in the somitogenesis clock of mice. Dev Dyn. 2006 Nov; 235(11):3177-83.
        View in: PubMed
      18. Fisher DA, Kivimäe S, Hoshino J, Suriben R, Martin PM, Baxter N, Cheyette BN. Three Dact gene family members are expressed during embryonic development and in the adult brains of mice. Dev Dyn. 2006 Sep; 235(9):2620-30.
        View in: PubMed
      19. Kovoor A, Seyffarth P, Ebert J, Barghshoon S, Chen CK, Schwarz S, Axelrod JD, Cheyette BN, Simon MI, Lester HA, Schwarz J. D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. J Neurosci. 2005 Feb 23; 25(8):2157-65.
        View in: PubMed
      20. Cheyette BN. Ryk: another heretical Wnt receptor defies the canon. Sci STKE. 2004 Dec 14; 2004(263):pe54.
        View in: PubMed
      21. Cheyette BN, Waxman JS, Miller JR, Takemaru K, Sheldahl LC, Khlebtsova N, Fox EP, Earnest T, Moon RT. Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation. Dev Cell. 2002 Apr; 2(4):449-61.
        View in: PubMed
      22. Oliver G, Wehr R, Jenkins NA, Copeland NG, Cheyette BN, Hartenstein V, Zipursky SL, Gruss P. Homeobox genes and connective tissue patterning. Development. 1995 Mar; 121(3):693-705.
        View in: PubMed
      23. Cheyette BN, Green PJ, Martin K, Garren H, Hartenstein V, Zipursky SL. The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system. Neuron. 1994 May; 12(5):977-96.
        View in: PubMed
      24. Ebens AJ, Garren H, Cheyette BN, Zipursky SL. The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation. Cell. 1993 Jul 16; 74(1):15-27.
        View in: PubMed
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