Vikaas Sohal, MD, PhD

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #415C
San Francisco CA 94158
ORCID ORCID Icon0000-0002-2238-4186 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences

    Collapse Biography 
    Collapse Education and Training
    Stanford University,, Stanford, CAM.D./Ph.D.06/2005Neuroscience
    University of Cambridge, U.K.M.A.St.06/1998Mathematics
    Harvard University, Cambridge, MAA.B., S.M.06/1997Applied Mathematics

    Collapse Overview 
    Collapse Overview
    Dr. Sohal directs a neuroscience laboratory that investigates the brain circuits underlying fundamental aspects of cognition and emotion. His laboratory has made important discoveries about the role of rhythmic patterns of brain activity called gamma oscillations in normal cognition and schizophrenia, and about how other rhythmic patterns of brain activity encode changes in emotional states. Dr. Sohal is also a board-certified psychiatrist who supervises residents in the Early Psychosis (PATH) clinic.

    After earning a bachelor's degree in applied mathematics at Harvard University, Dr. Sohal earned a master's degree in mathematics at the University of Cambridge in England. He earned his medical and doctoral degrees at Stanford University, where he also completed a residency in adult psychiatry. During residency Dr. Sohal carried out postdoctoral research in the laboratory of Dr Karl Deisseroth, performing some of the first experiments using optogenetics to study information processing in brain circuits.

    Collapse Research 
    Collapse Research Activities and Funding
    How do parvalbumin interneuron-generated gamma oscillations organize prefrontal networks to promote behavioral adaptation?
    NIH R01NS116594Apr 15, 2020 - Mar 31, 2023
    Role: Principal Investigator
    Using new methods for voltage imaging to assay the engagement of specific cell-types and brain rhythms in prefrontal-dependent cognition.
    NIH R01MH121342Sep 5, 2019 - Jun 30, 2023
    Role: Principal Investigator
    How is anxiety-related information relayed across hippocampal-prefrontal circuits
    NIH R01MH117961Aug 3, 2019 - Apr 30, 2023
    Role: Principal Investigator
    How is anxiety-related information relayed across hippocampal-prefrontal circuits
    NIH R56MH117961Aug 3, 2018 - Aug 2, 2019
    Role: Principal Investigator
    Restoring cognition by optogenetically rescuing gamma rhythms in PFC interneurons
    NIH R01MH106507Mar 1, 2015 - Feb 28, 2021
    Role: Principal Investigator
    Identification of enhancers whose activity defines cortical interneuron types
    NIH U01MH105948Sep 26, 2014 - May 31, 2018
    Role: Co-Principal Investigator
    Cellular and synaptic mechanisms for dopaminergic modulation of prefrontal cortex
    NIH R01MH100292Jul 5, 2013 - Apr 30, 2019
    Role: Principal Investigator
    Reverse engineering the prefrontal microcircuit
    NIH DP2MH100011Sep 30, 2012 - Aug 31, 2017
    Role: Principal Investigator
    Optogenetic Tools to Measure Information Processing in Prefrontal Microcircuits
    NIH R00MH085946Jul 6, 2009 - May 31, 2013
    Role: Principal Investigator
    Optogenetic Tools to Measure Information Processing in Prefrontal Microcircuits
    NIH K99MH085946Jul 6, 2009 - May 31, 2010
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders. Cell Stem Cell. 2024 03 07; 31(3):421-432.e8. Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, Cadwell CR, Bhaduri A, Popova G, Bearden CE, Pollen AA, Jacquemont S, Sanders SJ, Haussler D, Wiita AP, Frost NA, Sohal VS, Nowakowski TJ. PMID: 38382530; PMCID: PMC10939828.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Amygdala-hippocampus somatostatin interneuron beta-synchrony underlies a cross-species biomarker of emotional state. Neuron. 2024 Apr 03; 112(7):1182-1195.e5. Jackson AD, Cohen JL, Phensy AJ, Chang EF, Dawes HE, Sohal VS. PMID: 38266646; PMCID: PMC10994747.
      View in: PubMed   Mentions:    Fields:    
    3. Tsc1 Loss in VIP-Lineage Cortical Interneurons Results in More VIP+ Interneurons and Enhanced Excitability. Cells. 2023 12 26; 13(1). Hu JS, Malik R, Sohal VS, Rubenstein JL, Vogt D. PMID: 38201256; PMCID: PMC10777938.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Neurobiology of schizophrenia. Curr Opin Neurobiol. 2024 Feb; 84:102820. Sohal VS. PMID: 38091860.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Context-invariant socioemotional encoding by prefrontal ensembles. bioRxiv. 2023 Oct 23. Frost NA, Donohue KC, Sohal V. PMID: 37961143; PMCID: PMC10634670.
      View in: PubMed   Mentions:
    6. Long-range inhibition synchronizes and updates prefrontal task activity. Nature. 2023 May; 617(7961):548-554. Cho KKA, Shi J, Phensy AJ, Turner ML, Sohal VS. PMID: 37100905; PMCID: PMC10191848.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Selective Inhibitory Circuit Dysfunction after Chronic Frontal Lobe Contusion. J Neurosci. 2022 07 06; 42(27):5361-5372. Nolan AL, Sohal VS, Rosi S. PMID: 35610049; PMCID: PMC9270915.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Fate mapping of neural stem cell niches reveals distinct origins of human cortical astrocytes. Science. 2022 06 24; 376(6600):1441-1446. Allen DE, Donohue KC, Cadwell CR, Shin D, Keefe MG, Sohal VS, Nowakowski TJ. PMID: 35587512; PMCID: PMC9233096.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    9. P486. Cross-Hemispheric Gamma Synchrony in Prefrontal PVI and Subpopulations of Projection Neurons are Modulated Differentially in a Task-Dependent Manner. Biological Psychiatry. 2022 May 1; 91(9):s285. Phensy PA, Cho CK, Shi SJ, Sohal SV. .
      View in: Publisher Site   Mentions:
    10. Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition. Cell. 2022 04 28; 185(9):1602-1617.e17. Malik R, Li Y, Schamiloglu S, Sohal VS. PMID: 35487191; PMCID: PMC10027400.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    11. Transforming Discoveries About Cortical Microcircuits and Gamma Oscillations Into New Treatments for Cognitive Deficits in Schizophrenia. Am J Psychiatry. 2022 04; 179(4):267-276. Sohal VS. PMID: 35360913.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    12. Convergence of Clinically Relevant Manipulations on Dopamine-Regulated Prefrontal Activity Underlying Stress Coping Responses. Biol Psychiatry. 2022 05 01; 91(9):810-820. Wilke SA, Lavi K, Byeon S, Donohue KC, Sohal VS. PMID: 35090617.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    13. Dynamic patterns of correlated activity in the prefrontal cortex encode information about social behavior. PLoS Biol. 2021 05; 19(5):e3001235. Frost NA, Haggart A, Sohal VS. PMID: 33939689; PMCID: PMC8118626.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    14. Information diversity in individual auditory cortical neurons is associated with functionally distinct coordinated neuronal ensembles. Sci Rep. 2021 02 18; 11(1):4064. See JZ, Homma NY, Atencio CA, Sohal VS, Schreiner CE. PMID: 33603027; PMCID: PMC7893178.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    15. Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons. eNeuro. 2020 Nov/Dec; 7(6). Rubin AN, Malik R, Cho KKA, Lim KJ, Lindtner S, Robinson Schwartz SE, Vogt D, Sohal VS, Rubenstein JLR. PMID: 33199411; PMCID: PMC7768279.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    16. Altered hippocampal-prefrontal communication during anxiety-related avoidance in mice deficient for the autism-associated gene Pogz. Elife. 2020 11 06; 9. Cunniff MM, Markenscoff-Papadimitriou E, Ostrowski J, Rubenstein JL, Sohal VS. PMID: 33155545; PMCID: PMC7682992.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    17. GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons. PLoS One. 2020; 15(6):e0233895. Garst-Orozco J, Malik R, Lanz TA, Weber ML, Xi H, Arion D, Enwright JF, Lewis DA, O'Donnell P, Sohal VS, Buhl DL. PMID: 32497062; PMCID: PMC7272025.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    18. Cross-hemispheric gamma synchrony between prefrontal parvalbumin interneurons supports behavioral adaptation during rule shift learning. Nat Neurosci. 2020 07; 23(7):892-902. Cho KKA, Davidson TJ, Bouvier G, Marshall JD, Schnitzer MJ, Sohal VS. PMID: 32451483; PMCID: PMC7347248.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    19. Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants. Cell Rep. 2020 04 14; 31(2):107495. Fazel Darbandi S, Robinson Schwartz SE, Pai EL, Everitt A, Turner ML, Cheyette BNR, Willsey AJ, State MW, Sohal VS, Rubenstein JLR. PMID: 32294447; PMCID: PMC7473600.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    20. Integrated Stress Response Inhibitor Reverses Sex-Dependent Behavioral and Cell-Specific Deficits after Mild Repetitive Head Trauma. J Neurotrauma. 2020 06 01; 37(11):1370-1380. Krukowski K, Nolan A, Frias ES, Grue K, Becker M, Ureta G, Delgado L, Bernales S, Sohal VS, Walter P, Rosi S. PMID: 31884883; PMCID: PMC7249463.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    21. Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition. J Neurosci. 2020 03 11; 40(11):2215-2227. Southwell DG, Seifikar H, Malik R, Lavi K, Vogt D, Rubenstein JL, Sohal VS. PMID: 31988060; PMCID: PMC7083289.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons. Nat Commun. 2019 11 01; 10(1):4994. Malik R, Pai EL, Rubin AN, Stafford AM, Angara K, Minasi P, Rubenstein JL, Sohal VS, Vogt D. PMID: 31676823; PMCID: PMC6825152.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    23. GABAergic cell transplants in the anterior cingulate cortex reduce neuropathic pain aversiveness. Brain. 2019 09 01; 142(9):2655-2669. Juarez-Salinas DL, Braz JM, Etlin A, Gee S, Sohal V, Basbaum AI. PMID: 31321411; PMCID: PMC6752168.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    24. Interneuron Transplantation Creates New Network States and Rescues Social Behavior Deficits in a Mouse Model of Autism. Neurosurgery. 2019 Sep 1; 66(Supplement_1). Southwell SD, Seifikar SH, Malik MR, Lavi LK, Vogt VD, Rubenstein RJ, Sohal SV. .
      View in: Publisher Site   Mentions:
    25. Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders. Mol Psychiatry. 2019 09; 24(9):1248-1257. Sohal VS, Rubenstein JLR. PMID: 31089192; PMCID: PMC6742424.
      View in: PubMed   Mentions: 282     Fields:    Translation:HumansAnimalsCells
    26. VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks. Neuron. 2019 06 19; 102(6):1223-1234.e4. Lee AT, Cunniff MM, See JZ, Wilke SA, Luongo FJ, Ellwood IT, Ponnavolu S, Sohal VS. PMID: 31053407; PMCID: PMC6800223.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    27. Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. Neuron. 2019 06 05; 102(5):944-959.e3. Meda KS, Patel T, Braz JM, Malik R, Turner ML, Seifikar H, Basbaum AI, Sohal VS. PMID: 31030955; PMCID: PMC6554049.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    28. Ultrasonic sculpting of virtual optical waveguides in tissue. Nat Commun. 2019 01 09; 10(1):92. Chamanzar M, Scopelliti MG, Bloch J, Do N, Huh M, Seo D, Iafrati J, Sohal VS, Alam MR, Maharbiz MM. PMID: 30626873; PMCID: PMC6327026.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    29. Author Correction: The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms. Nat Commun. 2018 12 03; 9(1):5205. Incontro S, Díaz-Alonso J, Iafrati J, Vieira M, Asensio CS, Sohal VS, Roche KW, Bender KJ, Nicoll RA. PMID: 30510185; PMCID: PMC6277422.
      View in: PubMed   Mentions: 4     Fields:    
    30. An Amygdala-Hippocampus Subnetwork that Encodes Variation in Human Mood. Cell. 2018 11 29; 175(6):1688-1700.e14. Kirkby LA, Luongo FJ, Lee MB, Nahum M, Van Vleet TM, Rao VR, Dawes HE, Chang EF, Sohal VS. PMID: 30415834.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCTClinical Trials
    31. Mouse Cntnap2 and Human CNTNAP2 ASD Alleles Cell Autonomously Regulate PV+ Cortical Interneurons. Cereb Cortex. 2018 11 01; 28(11):3868-3879. Vogt D, Cho KKA, Shelton SM, Paul A, Huang ZJ, Sohal VS, Rubenstein JLR. PMID: 29028946; PMCID: PMC6455910.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    32. Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity. Neuron. 2018 11 21; 100(4):831-845.e7. Fazel Darbandi S, Robinson Schwartz SE, Qi Q, Catta-Preta R, Pai EL, Mandell JD, Everitt A, Rubin A, Krasnoff RA, Katzman S, Tastad D, Nord AS, Willsey AJ, Chen B, State MW, Sohal VS, Rubenstein JLR. PMID: 30318412; PMCID: PMC6250594.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    33. Upconverting nanoparticle micro-lightbulbs designed for deep tissue optical stimulation and imaging. Biomed Opt Express. 2018 Sep 01; 9(9):4359-4371. Chamanzar M, Garfield DJ, Iafrati J, Chan EM, Sohal V, Cohen BE, Schuck PJ, Maharbiz MM. PMID: 30615722; PMCID: PMC6157781.
      View in: PubMed   Mentions: 3  
    34. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 2018 07 26; 174(3):505-520. Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ. PMID: 30053424; PMCID: PMC6247911.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    35. Repeated Mild Head Injury Leads to Wide-Ranging Deficits in Higher-Order Cognitive Functions Associated with the Prefrontal Cortex. J Neurotrauma. 2018 10 15; 35(20):2425-2434. Nolan A, Hennessy E, Krukowski K, Guglielmetti C, Chaumeil MM, Sohal VS, Rosi S. PMID: 29732949; PMCID: PMC6196749.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    36. Coordinated neuronal ensembles in primary auditory cortical columns. Elife. 2018 06 05; 7. See JZ, Atencio CA, Sohal VS, Schreiner CE. PMID: 29869986; PMCID: PMC6017807.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    37. The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms. Nat Commun. 2018 05 25; 9(1):2069. Incontro S, Díaz-Alonso J, Iafrati J, Vieira M, Asensio CS, Sohal VS, Roche KW, Bender KJ, Nicoll RA. PMID: 29802289; PMCID: PMC5970233.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    38. Roles of Prefrontal Cortex and Mediodorsal Thalamus in Task Engagement and Behavioral Flexibility. J Neurosci. 2018 03 07; 38(10):2569-2578. Marton TF, Seifikar H, Luongo FJ, Lee AT, Sohal VS. PMID: 29437889; PMCID: PMC5858597.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    39. A Shared Vision for Machine Learning in Neuroscience. J Neurosci. 2018 02 14; 38(7):1601-1607. Vu MT, Adali T, Ba D, Buzsáki G, Carlson D, Heller K, Liston C, Rudin C, Sohal VS, Widge AS, Mayberg HS, Sapiro G, Dzirasa K. PMID: 29374138; PMCID: PMC5815449.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    40. A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry. Nat Commun. 2018 01 23; 9(1):330. Ullman JC, Yang J, Sullivan M, Bendor J, Levy J, Pham E, Silm K, Seifikar H, Sohal VS, Nicoll RA, Edwards RH. PMID: 29362376; PMCID: PMC5780507.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    41. Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons. Elife. 2017 12 05; 6. Athilingam JC, Ben-Shalom R, Keeshen CM, Sohal VS, Bender KJ. PMID: 29206101; PMCID: PMC5746342.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    42. Identifying specific prefrontal neurons that contribute to autism-associated abnormalities in physiology and social behavior. Mol Psychiatry. 2018 10; 23(10):2078-2089. Brumback AC, Ellwood IT, Kjaerby C, Iafrati J, Robinson S, Lee AT, Patel T, Nagaraj S, Davatolhagh F, Sohal VS. PMID: 29112191; PMCID: PMC6594833.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    43. The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice. Neurosci Lett. 2018 Jan 01; 662:29-35. von Schoubye NL, Frederiksen K, Kristiansen U, Petersen AV, Dalby NO, Grunnet M, Jensen HS, Jespersen T, Sohal VS, Perrier JF. PMID: 28987817.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    44. Dopamine D2 Receptors Modulate Pyramidal Neurons in Mouse Medial Prefrontal Cortex through a Stimulatory G-Protein Pathway. J Neurosci. 2017 10 18; 37(42):10063-10073. Robinson SE, Sohal VS. PMID: 28912160; PMCID: PMC5647767.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    45. The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex. Cereb Cortex. 2017 09 01; 27(9):4303-4313. Wu PR, Cho KKA, Vogt D, Sohal VS, Rubenstein JLR. PMID: 27497284; PMCID: PMC6410508.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    46. Tonic or Phasic Stimulation of Dopaminergic Projections to Prefrontal Cortex Causes Mice to Maintain or Deviate from Previously Learned Behavioral Strategies. J Neurosci. 2017 08 30; 37(35):8315-8329. Ellwood IT, Patel T, Wadia V, Lee AT, Liptak AT, Bender KJ, Sohal VS. PMID: 28739583; PMCID: PMC5577850.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    47. D3 Receptors Regulate Excitability in a Unique Class of Prefrontal Pyramidal Cells. J Neurosci. 2017 06 14; 37(24):5846-5860. Clarkson RL, Liptak AT, Gee SM, Sohal VS, Bender KJ. PMID: 28522735; PMCID: PMC5473204.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    48. 499 Disrupted Activity in Prefrontal Microcircuits in a Mouse Model of Genetic Risk for Psychiatric Illness. Biological Psychiatry. 2017 May 1; 81(10):s203. Wilke WS, Sohal SV. .
      View in: Publisher Site   Mentions:
    49. 706 Wnt/ß-Catenin Pathway Contributions to Dendritic Spine and Glutamatergic Synapse Formation Responsive to Lithium-Mediated GSK3 Inhibition. Biological Psychiatry. 2017 May 1; 81(10):s286. Stanley SR, Martin MP, Ross RA, Freitas FA, Iafrati IJ, Moyer MC, Brumback BA, Pirooznia PM, McCombie MW, Potash PJ, Zandi ZP, Purcell PS, Sanders SS, Zuo ZY, Sohal SV, Cheyette CB. .
      View in: Publisher Site   Mentions:
    50. 336 VIP Interneuron Cholinergic Responses are Altered in Multiple Models of Autism. Biological Psychiatry. 2017 May 1; 81(10):s138. Cunniff CM, Sohal SV. .
      View in: Publisher Site   Mentions:
    51. Immediate Mood Scaler: Tracking Symptoms of Depression and Anxiety Using a Novel Mobile Mood Scale. JMIR Mhealth Uhealth. 2017 Apr 12; 5(4):e44. Nahum M, Van Vleet TM, Sohal VS, Mirzabekov JJ, Rao VR, Wallace DL, Lee MB, Dawes H, Stark-Inbar A, Jordan JT, Biagianti B, Merzenich M, Chang EF. PMID: 28404542; PMCID: PMC5406620.
      View in: PubMed   Mentions: 28     Fields:    
    52. Dynamic, Cell-Type-Specific Roles for GABAergic Interneurons in a Mouse Model of Optogenetically Inducible Seizures. Neuron. 2017 Jan 18; 93(2):291-298. Khoshkhoo S, Vogt D, Sohal VS. PMID: 28041880; PMCID: PMC5268075.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    53. Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs. Cell Rep. 2016 12 13; 17(11):2882-2890. Kjaerby C, Athilingam J, Robinson SE, Iafrati J, Sohal VS. PMID: 27974203; PMCID: PMC5268074.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    54. DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. Mol Psychiatry. 2018 02; 23(2):467-475. Martin PM, Stanley RE, Ross AP, Freitas AE, Moyer CE, Brumback AC, Iafrati J, Stapornwongkul KS, Dominguez S, Kivimäe S, Mulligan KA, Pirooznia M, McCombie WR, Potash JB, Zandi PP, Purcell SM, Sanders SJ, Zuo Y, Sohal VS, Cheyette BNR. PMID: 27752079; PMCID: PMC5395363.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    55. How Close Are We to Understanding What (if Anything) γ Oscillations Do in Cortical Circuits? J Neurosci. 2016 10 12; 36(41):10489-10495. Sohal VS. PMID: 27733600; PMCID: PMC5059424.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    56. Making the Right Connections. Biol Psychiatry. 2016 10 01; 80(7):502-3. Lee AT, Sohal VS. PMID: 27601338.
      View in: PubMed   Mentions:    Fields:    
    57. Energy-Looping Nanoparticles: Harnessing Excited-State Absorption for Deep-Tissue Imaging. ACS Nano. 2016 09 27; 10(9):8423-33. Levy ES, Tajon CA, Bischof TS, Iafrati J, Fernandez-Bravo A, Garfield DJ, Chamanzar M, Maharbiz MM, Sohal VS, Schuck PJ, Cohen BE, Chan EM. PMID: 27603228.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    58. Stressing out the Social Network. Neuron. 2016 07 20; 91(2):210-3. Kirkby LA, Sohal VS. PMID: 27477012.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    59. Correlations between prefrontal neurons form a small-world network that optimizes the generation of multineuron sequences of activity. J Neurophysiol. 2016 05 01; 115(5):2359-75. Luongo FJ, Zimmerman CA, Horn ME, Sohal VS. PMID: 26888108; PMCID: PMC5394653.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    60. A point-process response model for spike trains from single neurons in neural circuits under optogenetic stimulation. Stat Med. 2016 Feb 10; 35(3):455-74. Luo X, Gee S, Sohal V, Small D. PMID: 26411923; PMCID: PMC4713323.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    61. Deep tissue targeted near-infrared optogenetic stimulation using fully implantable upconverting light bulbs. Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug; 2015:821-4. Chamanzar M, Garfield DJ, Iafrati J, Sohal V, Chan E, Cohen B, Schuck PJ, Maharbiz MM. PMID: 26736388.
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    62. Neural Oscillations and Synchrony in Brain Dysfunction and Neuropsychiatric Disorders: It's About Time. JAMA Psychiatry. 2015 Aug; 72(8):840-4. Mathalon DH, Sohal VS. PMID: 26039190.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    63. The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles. Cell Rep. 2015 May 12; 11(6):944-956. Vogt D, Cho KKA, Lee AT, Sohal VS, Rubenstein JLR. PMID: 25937288; PMCID: PMC4431948.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    64. Putative Microcircuit-Level Substrates for Attention Are Disrupted in Mouse Models of Autism. Biol Psychiatry. 2016 Apr 15; 79(8):667-75. Luongo FJ, Horn ME, Sohal VS. PMID: 26022075; PMCID: PMC4624609.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    65. Of Mice, Men, and Microbial Opsins: How Optogenetics Can Help Hone Mouse Models of Mental Illness. Biol Psychiatry. 2016 Jan 01; 79(1):47-52. Marton TF, Sohal VS. PMID: 25981174; PMCID: PMC4618781.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    66. Gamma rhythms link prefrontal interneuron dysfunction with cognitive inflexibility in Dlx5/6(+/-) mice. Neuron. 2015 Mar 18; 85(6):1332-43. Cho KK, Hoch R, Lee AT, Patel T, Rubenstein JL, Sohal VS. PMID: 25754826; PMCID: PMC4503262.
      View in: PubMed   Mentions: 160     Fields:    Translation:AnimalsCells
    67. Identifying pathways leading to prefrontal GABA-ergic interneuron dysfunction in schizophrenia. Am J Psychiatry. 2014 Sep; 171(9):906-9. Sohal VS. PMID: 25178745.
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    68. A class of GABAergic neurons in the prefrontal cortex sends long-range projections to the nucleus accumbens and elicits acute avoidance behavior. J Neurosci. 2014 Aug 27; 34(35):11519-25. Lee AT, Vogt D, Rubenstein JL, Sohal VS. PMID: 25164650; PMCID: PMC4145166.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    69. Optogenetic approaches for investigating neural pathways implicated in schizophrenia and related disorders. Hum Mol Genet. 2014 Sep 15; 23(R1):R64-8. Cho KK, Sohal VS. PMID: 24824218.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    70. Intrinsic Excitability Defects in Specific Subtypes of Medial Prefrontal Cortex Pyramidal Neurons in a Mouse Model of Autism (I4-1.010). Neurology. 2014 Apr 8; 82(10_supplement). Brumback BA, Sohal SV. .
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    71. Intrinsic Excitability Defects in Specific Subtypes of Medial Prefrontal Cortex Pyramidal Neurons in a Mouse Model of Autism (P7.329). Neurology. 2014 Apr 8; 82(10_supplement). Brumback BA, Sohal SV. .
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    72. You Have Your Father’s Nose. Science Translational Medicine. 2014 Feb 26; 6(225). Sohal SV. .
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    73. Releasing the Brake Drives Fear Behavior. Science Translational Medicine. 2014 Jan 15; 6(219). Sohal SV. .
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    74. Pyramidal neurons in prefrontal cortex receive subtype-specific forms of excitation and inhibition. Neuron. 2014 Jan 08; 81(1):61-8. Lee AT, Gee SM, Vogt D, Patel T, Rubenstein JL, Sohal VS. PMID: 24361076; PMCID: PMC3947199.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    75. Too Much of a Good Thing?. Science Translational Medicine. 2013 Nov 27; 5(213). Sohal SV. .
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    76. Serotonin Gives Oxytocin a Helping Hand. Science Translational Medicine. 2013 Oct 16; 5(207). Sohal SV. .
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    77. Seeing the Big Picture in Fragile X Syndrome. Science Translational Medicine. 2013 Sep 4; 5(201). Sohal SV. .
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    78. Transplanting Interneuron Precursors for Epilepsy Control. Science Translational Medicine. 2013 Jul 24; 5(195). Sohal SV. .
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    79. Autism in the Balance. Science Translational Medicine. 2013 Jun 12; 5(189). Sohal SV. .
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    80. Stimulating the Prefrontal Cortex to Undo Stimulant Addiction. Science Translational Medicine. 2013 May 1; 5(183). Sohal SV. .
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    81. Neurons Themselves May Shy Away from Normal Interactions in Autism. Science Translational Medicine. 2013 Mar 20; 5(177). Sohal SV. .
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    82. Chronic reduction in inhibition reduces receptive field size in mouse auditory cortex. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13829-34. Seybold BA, Stanco A, Cho KK, Potter GB, Kim C, Sohal VS, Rubenstein JL, Schreiner CE. PMID: 22753490; PMCID: PMC3427089.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    83. Synaptic activity unmasks dopamine D2 receptor modulation of a specific class of layer V pyramidal neurons in prefrontal cortex. J Neurosci. 2012 Apr 04; 32(14):4959-71. Gee S, Ellwood I, Patel T, Luongo F, Deisseroth K, Sohal VS. PMID: 22492051; PMCID: PMC3352768.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    84. Insights into cortical oscillations arising from optogenetic studies. Biol Psychiatry. 2012 Jun 15; 71(12):1039-45. Sohal VS. PMID: 22381731; PMCID: PMC3361599.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    85. Responsive neurostimulation suppresses synchronized cortical rhythms in patients with epilepsy. Neurosurg Clin N Am. 2011 Oct; 22(4):481-8, vi. Sohal VS, Sun FT. PMID: 21939847.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    86. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature. 2011 Jul 27; 477(7363):171-8. Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT, Stehfest K, Fudim R, Ramakrishnan C, Huguenard JR, Hegemann P, Deisseroth K. PMID: 21796121; PMCID: PMC4155501.
      View in: PubMed   Mentions: 1166     Fields:    Translation:HumansAnimalsCells
    87. Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. J Neurosci. 2010 Apr 14; 30(15):5334-45. Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL. PMID: 20392955; PMCID: PMC2919857.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    88. Ultrafast optogenetic control. Nat Neurosci. 2010 Mar; 13(3):387-92. Gunaydin LA, Yizhar O, Berndt A, Sohal VS, Deisseroth K, Hegemann P. PMID: 20081849.
      View in: PubMed   Mentions: 329     Fields:    Translation:AnimalsCells
    89. Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature. 2009 Jun 04; 459(7247):698-702. Sohal VS, Zhang F, Yizhar O, Deisseroth K. PMID: 19396159; PMCID: PMC3969859.
      View in: PubMed   Mentions: 1299     Fields:    Translation:AnimalsCells
    90. Intrinsic and synaptic dynamics interact to generate emergent patterns of rhythmic bursting in thalamocortical neurons. J Neurosci. 2006 Apr 19; 26(16):4247-55. Sohal VS, Pangratz-Fuehrer S, Rudolph U, Huguenard JR. PMID: 16624945; PMCID: PMC6674011.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    91. Inhibitory coupling specifically generates emergent gamma oscillations in diverse cell types. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18638-43. Sohal VS, Huguenard JR. PMID: 16339306; PMCID: PMC1317969.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    92. Inhibitory interconnections control burst pattern and emergent network synchrony in reticular thalamus. J Neurosci. 2003 Oct 01; 23(26):8978-88. Sohal VS, Huguenard JR. PMID: 14523100; PMCID: PMC6740384.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    93. Dynamic GABA(A) receptor subtype-specific modulation of the synchrony and duration of thalamic oscillations. J Neurosci. 2003 May 01; 23(9):3649-57. Sohal VS, Keist R, Rudolph U, Huguenard JR. PMID: 12736336; PMCID: PMC6742195.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    94. Reciprocal inhibition controls the oscillatory state in thalamic networks. Neurocomputing. 2002 Jun 1; 44:653-659. Sohal SV, Huguenard HJ. .
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    95. Clonazepam suppresses oscillations in rat thalamic slices. Neurocomputing. 2001 Jun 1; 38:907-913. Sohal SV, Huguenard HJ. .
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    96. A model for experience-dependent changes in the responses of inferotemporal neurons. Network. 2000 Aug; 11(3):169-90. Sohal VS, Hasselmo ME. PMID: 11014667.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    97. Reciprocal inhibitory connections produce desynchronizing phase lags during intrathalamic oscillations. Neurocomputing. 2000 Jun 1; 32:509-516. Sohal SV, Huntsman HM, Huguenard HJ. .
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    98. Reciprocal inhibitory connections regulate the spatiotemporal properties of intrathalamic oscillations. J Neurosci. 2000 Mar 01; 20(5):1735-45. Sohal VS, Huntsman MM, Huguenard JR. PMID: 10684875; PMCID: PMC6772943.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    99. A model for experience-dependent changes in the responses of inferotemporal neurons. Network Computation in Neural Systems. 2000 Jan 1; 11(3):169-190. Sohal SV, Hasselmo HM. .
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    100. Long-range connections synchronize rather than spread intrathalamic oscillatory activity: Computational modeling and in vitro electrophysiology. Neurocomputing. 1999 Jun 1; 26:525-531. Sohal SV, Huguenard HJ. .
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    101. Long-range connections synchronize rather than spread intrathalamic oscillations: computational modeling and in vitro electrophysiology. J Neurophysiol. 1998 Oct; 80(4):1736-51. Sohal VS, Huguenard JR. PMID: 9772235.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    102. Changes in GABAB modulation during a theta cycle may be analogous to the fall of temperature during annealing. Neural Comput. 1998 May 15; 10(4):869-82. Sohal VS, Hasselmo ME. PMID: 9573410.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    103. Localization of CCK receptors in thalamic reticular neurons: a modeling study. J Neurophysiol. 1998 May; 79(5):2820-4. Sohal VS, Cox CL, Huguenard JR. PMID: 9582249.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    104. GABA(B) modulation improves sequence disambiguation in computational models of hippocampal region CA3. Hippocampus. 1998; 8(2):171-93. Sohal VS, Hasselmo ME. PMID: 9572723.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    105. A Mathematical Description for Gabaergic Modulation of Sequence Disambiguation in Hippocampal Region CA3. Computational Neuroscience. 1998 Jan 1; 525-530. Sohal SV, Hasselmo HM. .
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    106. A Model of Changes in Inferotemporal Activity during a Delayed Match-To-Sample Task. Computational Neuroscience. 1997 Jan 1; 845-850. Sohal SV, Hasselmo HM. .
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