Loading...

Jane Koehler, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-476-3536
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    University of California, San FranciscoResearch Post-Doc Fellow1992Infectious Diseases
    University of California, San FranciscoClinical Fellow1988Infectious Diseases
    University of California, San FranciscoIntern and Resident1987Internal Medicine
    George Washington UniversityM.D.1984School of Medicine
    University of California, BerkeleyM.A.Microbiology and Immunology
    Vassar CollegeA.B.Biology
    Collapse Awards and Honors
    Infectious Diseases Society of America2012Elected Fellow
    Infectious Diseases Society of America2011Walter E. Stamm Mentor Award
    Infectious Diseases Society of America2008Smadel Lecture (named scientific award lecture)
    UCSF2008Chancellor’s Award for the Advancement of Women
    Burroughs Wellcome Fund 2003 - 2008Clinical Scientist Award in Translational Research
    2002 - 2003Executive Leadership in Academic Medicine (ELAM) Fellow
    Massachusetts General Hospital2001Ann Sullivan Baker Visiting Professorship
    1997American Society for Clinical Investigation
    American Society for Microbiology1994ICAAC Young Investigator Award
    1994 - 1998Pew Scholar in the Biomedical Sciences
    George Washington University School of Medicine1984Graduation with Distinction
    American Medical Women's Association 1984Scholarship Achievement Citation
    George Washington University School of Medicine1983Alpha Omega Alpha Honor Medical Society, Junior Year Initiate

    Collapse Research 
    Collapse Research Activities and Funding
    Bartonella: dissecting niche-specific adaptation in a human pathogen
    NIH/NIAID R01AI103299Jul 1, 2013 - Jun 30, 2017
    Role: Principal Investigator
    Mechanisms of Bartonella Virulence in AIDS Patients
    NIH/NIAID R01AI052813Jul 1, 2002 - May 31, 2014
    Role: Principal Investigator
    BARTONELLA--A MODEL FOR AN AIDS OPPORTUNISTIC PATHOGEN
    NIH/NIAID R01AI043703Dec 1, 1998 - Nov 30, 2004
    Role: Principal Investigator
    ROCHALIMAEA--AN EMERGING PATHOGEN OF AIDS
    NIH/NIAID R29AI036075May 1, 1994 - Apr 30, 1999
    Role: Principal Investigator
    California National Primate Research Center
    NIH P51RR000169Jun 1, 1975 - Apr 30, 2015
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Faculty Mentoring
    Collapse Clinical Trials
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Selected Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Chomel BB, Molia S, Kasten RW, Borgo GM, Stuckey MJ, Maruyama S, Chang CC, Haddad N, Koehler JE. Isolation of Bartonella henselae and Two New Bartonella Subspecies, Bartonellakoehlerae Subspecies boulouisii subsp. nov. and Bartonella koehlerae Subspecies bothieri subsp. nov. from Free-Ranging Californian Mountain Lions and Bobcats. PLoS One. 2016; 11(3):e0148299. PMID: 26981874.
      View in: PubMed
    2. Lee SA, Plett SK, Luetkemeyer AF, Borgo GM, Ohliger MA, Conrad MB, Cookson BT, Sengupta DJ, Koehler JE. Bartonella quintana Aortitis in a Man with AIDS, Diagnosed by Needle Biopsy and 16S rRNA Gene Amplification. J Clin Microbiol. 2015 Aug; 53(8):2773-6. PMID: 26063867; PMCID: PMC4508458 [Available on 02/01/16].
    3. Chomel BB, Kasten RW, Stuckey MJ, Breitschwerdt EB, Maggi RG, Henn JB, Koehler JE, Chang CC. Experimental infection of cats with Afipia felis and various Bartonella species or subspecies. Vet Microbiol. 2014 Aug 27; 172(3-4):505-10. PMID: 24972870.
      View in: PubMed
    4. Abromaitis S, Koehler JE. The Bartonella quintana extracytoplasmic function sigma factor RpoE has a role in bacterial adaptation to the arthropod vector environment. J Bacteriol. 2013 Jun; 195(11):2662-74. PMID: 23564167; PMCID: PMC3676067.
    5. Abromaitis S, Nelson CS, Previte D, Yoon KS, Clark JM, DeRisi JL, Koehler JE. Bartonella quintana deploys host and vector temperature-specific transcriptomes. PLoS One. 2013; 8(3):e58773. PMID: 23554923; PMCID: PMC3595295.
    6. Doyon JB, Sutton DA, Theodore P, Dhillon G, Jones KD, Thompson EH, Fu J, Wickes BL, Koehler JE, Schwartz BS. Rasamsonia argillacea pulmonary and aortic graft infection in an immune-competent patient. J Clin Microbiol. 2013 Feb; 51(2):719-22. PMID: 23241382; PMCID: PMC3553912.
    7. Roden JA, Wells DH, Chomel BB, Kasten RW, Koehler JE. Hemin binding protein C is found in outer membrane vesicles and protects Bartonella henselae against toxic concentrations of hemin. Infect Immun. 2012 Mar; 80(3):929-42. PMID: 22232189; PMCID: PMC3294634.
    8. Vigil A, Ortega R, Jain A, Nakajima-Sasaki R, Tan X, Chomel BB, Kasten RW, Koehler JE, Felgner PL. Identification of the feline humoral immune response to Bartonella henselae infection by protein microarray. PLoS One. 2010; 5(7):e11447. PMID: 20625509; PMCID: PMC2897887.
    9. Chomel BB, Henn JB, Kasten RW, Nieto NC, Foley J, Papageorgiou S, Allen C, Koehler JE. Dogs are more permissive than cats or guinea pigs to experimental infection with a human isolate of Bartonella rochalimae. Vet Res. 2009 Jul-Aug; 40(4):27. PMID: 19272295.
      View in: PubMed
    10. Bouchouicha R, Durand B, Monteil M, Chomel BB, Berrich M, Arvand M, Birtles RJ, Breitschwerdt EB, Koehler JE, Maggi R, Maruyama S, Kasten R, Petit E, Boulouis HJ, Haddad N. Molecular epidemiology of feline and human Bartonella henselae isolates. Emerg Infect Dis. 2009 May; 15(5):813-6. PMID: 19402978; PMCID: PMC2687025.
    11. Chomel BB, Boulouis HJ, Breitschwerdt EB, Kasten RW, Vayssier-Taussat M, Birtles RJ, Koehler JE, Dehio C. Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors. Vet Res. 2009 Mar-Apr; 40(2):29. PMID: 19284965; PMCID: PMC2695021.
    12. Henn JB, Gabriel MW, Kasten RW, Brown RN, Koehler JE, MacDonald KA, Kittleson MD, Thomas WP, Chomel BB. Infective endocarditis in a dog and the phylogenetic relationship of the associated "Bartonella rochalimae" strain with isolates from dogs, gray foxes, and a human. J Clin Microbiol. 2009 Mar; 47(3):787-90. PMID: 19109472; PMCID: PMC2650912.
    13. MacKichan JK, Gerns HL, Chen YT, Zhang P, Koehler JE. A SacB mutagenesis strategy reveals that the Bartonella quintana variably expressed outer membrane proteins are required for bloodstream infection of the host. Infect Immun. 2008 Feb; 76(2):788-95. PMID: 18070893; PMCID: PMC2223462.
    14. Eremeeva ME, Gerns HL, Lydy SL, Goo JS, Ryan ET, Mathew SS, Ferraro MJ, Holden JM, Nicholson WL, Dasch GA, Koehler JE. Bacteremia, fever, and splenomegaly caused by a newly recognized bartonella species. N Engl J Med. 2007 Jun 7; 356(23):2381-7. PMID: 17554119.
      View in: PubMed
    15. Boonjakuakul JK, Gerns HL, Chen YT, Hicks LD, Minnick MF, Dixon SE, Hall SC, Koehler JE. Proteomic and immunoblot analyses of Bartonella quintana total membrane proteins identify antigens recognized by sera from infected patients. Infect Immun. 2007 May; 75(5):2548-61. PMID: 17307937; PMCID: PMC1865797.
    16. Koehler JE, Duncan LM. Case records of the Massachusetts General Hospital. Case 30-2005. A 56-year-old man with fever and axillary lymphadenopathy. N Engl J Med. 2005 Sep 29; 353(13):1387-94. PMID: 16192484.
      View in: PubMed
    17. Zhang P, Chomel BB, Schau MK, Goo JS, Droz S, Kelminson KL, George SS, Lerche NW, Koehler JE. A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13630-5. PMID: 15347808; PMCID: PMC518805.
    18. Koehler JE, Sanchez MA, Tye S, Garrido-Rowland CS, Chen FM, Maurer T, Cooper JL, Olson JG, Reingold AL, Hadley WK, Regnery RR, Tappero JW. Prevalence of Bartonella infection among human immunodeficiency virus-infected patients with fever. Clin Infect Dis. 2003 Aug 15; 37(4):559-66. PMID: 12905141.
      View in: PubMed
    19. Yamamoto K, Chomel BB, Kasten RW, Hew CM, Weber DK, Lee WI, Koehler JE, Pedersen NC. Infection and re-infection of domestic cats with various Bartonella species or types: B. henselae type I is protective against heterologous challenge with B. henselae type II. Vet Microbiol. 2003 Mar 20; 92(1-2):73-86. PMID: 12488072.
      View in: PubMed
    20. Chang CC, Chomel BB, Kasten RW, Tappero JW, Sanchez MA, Koehler JE. Molecular epidemiology of Bartonella henselae infection in human immunodeficiency virus-infected patients and their cat contacts, using pulsed-field gel electrophoresis and genotyping. J Infect Dis. 2002 Dec 15; 186(12):1733-9. PMID: 12447758.
      View in: PubMed
    21. Yamamoto K, Chomel BB, Kasten RW, Hew CM, Weber DK, Lee WI, Droz S, Koehler JE. Experimental infection of domestic cats with Bartonella koehlerae and comparison of protein and DNA profiles with those of other Bartonella species infecting felines. J Clin Microbiol. 2002 Feb; 40(2):466-74. PMID: 11825958; PMCID: PMC153398.
    22. Park SY, Kelminson KL, Lee AK, Zhang P, Warner RE, Rehkopf DH, Calderwood SB, Koehler JE. Identification, characterization, and functional analysis of a gene encoding the ferric uptake regulation protein in Bartonella species. J Bacteriol. 2001 Oct; 183(19):5751-5. PMID: 11544240; PMCID: PMC95469.
    23. Cunningham ET, Koehler JE. Ocular bartonellosis. Am J Ophthalmol. 2000 Sep; 130(3):340-9. PMID: 11020414.
      View in: PubMed
    24. George TI, Manley G, Koehler JE, Hung VS, McDermott M, Bollen A. Detection of Bartonella henselae by polymerase chain reaction in brain tissue of an immunocompromised patient with multiple enhancing lesions. Case report and review of the literature. J Neurosurg. 1998 Oct; 89(4):640-4. PMID: 9761060.
      View in: PubMed
    25. Bradford WZ, Koehler J, El-Hajj H, Hopewell PC, Reingold AL, Agasino CB, Cave MD, Rane S, Yang Z, Crane CM, Small PM. Dissemination of Mycobacterium tuberculosis across the San Francisco Bay Area. J Infect Dis. 1998 Apr; 177(4):1104-7. PMID: 9534993.
      View in: PubMed
    26. Koehler JE, Sanchez MA, Garrido CS, Whitfeld MJ, Chen FM, Berger TG, Rodriguez-Barradas MC, LeBoit PE, Tappero JW. Molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis. N Engl J Med. 1997 Dec 25; 337(26):1876-83. PMID: 9407154.
      View in: PubMed
    27. Whitfeld MJ, Kaveh S, Koehler JE, Mead P, Berger TG. Bacillary angiomatosis associated with myositis in a patient infected with human immunodeficiency virus. Clin Infect Dis. 1997 Apr; 24(4):562-4. PMID: 9145727.
      View in: PubMed
    28. Long SR, Whitfeld MJ, Eades C, Koehler JE, Korn AP, Zaloudek CJ. Bacillary angiomatosis of the cervix and vulva in a patient with AIDS. Obstet Gynecol. 1996 Oct; 88(4 Pt 2):709-11. PMID: 8841262.
      View in: PubMed
    29. Koehler JE. Bartonella infections. Adv Pediatr Infect Dis. 1996; 11:1-27. PMID: 8718458.
      View in: PubMed
    30. Koehler JE, Cederberg L. Intra-abdominal mass associated with gastrointestinal hemorrhage: a new manifestation of bacillary angiomatosis. Gastroenterology. 1995 Dec; 109(6):2011-4. PMID: 7498668.
      View in: PubMed
    31. Koehler JE. Bartonella-associated infections in HIV-infected patients. AIDS Clin Care. 1995 Dec; 7(12):97-102. PMID: 11362939.
      View in: PubMed
    32. Koehler JE, Glaser CA, Tappero JW. Rochalimaea henselae infection. A new zoonosis with the domestic cat as reservoir. JAMA. 1994 Feb 16; 271(7):531-5. PMID: 8301768.
      View in: PubMed
    33. Koehler JE, Tappero JW. Bacillary angiomatosis and bacillary peliosis in patients infected with human immunodeficiency virus. Clin Infect Dis. 1993 Oct; 17(4):612-24. PMID: 8268340.
      View in: PubMed
    34. Tappero JW, Koehler JE, Berger TG, Cockerell CJ, Lee TH, Busch MP, Stites DP, Mohle-Boetani J, Reingold AL, LeBoit PE. Bacillary angiomatosis and bacillary splenitis in immunocompetent adults. Ann Intern Med. 1993 Mar 1; 118(5):363-5. PMID: 8430982.
      View in: PubMed
    35. Tappero JW, Mohle-Boetani J, Koehler JE, Swaminathan B, Berger TG, LeBoit PE, Smith LL, Wenger JD, Pinner RW, Kemper CA. The epidemiology of bacillary angiomatosis and bacillary peliosis. JAMA. 1993 Feb 10; 269(6):770-5. PMID: 8423659.
      View in: PubMed
    36. Berger TG, Koehler JE. Bacillary angiomatosis. AIDS Clin Rev. 1993-1994; 43-60. PMID: 8217903.
      View in: PubMed
    37. Koehler J, Quinn FD, Berger TG, LeBoit PE, Tappero JW. Isolation of Rochalimaea species from cutaneous and osseous lesions of bacillary angiomatosis. N Engl J Med. 1992 Dec 3; 327(23):1625-31. PMID: 1435899.
      View in: PubMed
    38. Koehler J, Birkelund S, Stephens RS. Overexpression and surface localization of the Chlamydia trachomatis major outer membrane protein in Escherichia coli. Mol Microbiol. 1992 May; 6(9):1087-94. PMID: 1588812.
      View in: PubMed
    39. Koehler JE, Burgess RR, Thompson NE, Stephens RS. Chlamydia trachomatis RNA polymerase major sigma subunit. Sequence and structural comparison of conserved and unique regions with Escherichia coli sigma 70 and Bacillus subtilis sigma 43. J Biol Chem. 1990 Aug 5; 265(22):13206-14. PMID: 2142944.
      View in: PubMed
    40. Erlich KS, Jacobson MA, Koehler JE, Follansbee SE, Drennan DP, Gooze L, Safrin S, Mills J. Foscarnet therapy for severe acyclovir-resistant herpes simplex virus type-2 infections in patients with the acquired immunodeficiency syndrome (AIDS). An uncontrolled trial. Ann Intern Med. 1989 May 1; 110(9):710-3. PMID: 2522751.
      View in: PubMed
    41. Koehler JE, LeBoit PE, Egbert BM, Berger TG. Cutaneous vascular lesions and disseminated cat-scratch disease in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. Ann Intern Med. 1988 Sep 15; 109(6):449-55. PMID: 3415105.
      View in: PubMed
    Jane's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP