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Cristina Alvira, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
AddressSan Francisco CA 94158
PronounsShe/Her/Hers
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    Pericytes and postnatal alveolarization: Role of hypoxia inducible factors
    NIH R01HL160018May 1, 2022 - Apr 30, 2026
    Role: Co-Principal Investigator
    Developmental Heterogeneity of Pulmonary Endothelial Phenotype at Single Cell Resolution
    NIH R01HL154002Sep 15, 2021 - Jul 31, 2025
    Role: Principal Investigator
    Diverse Homeostatic Roles for Distinct Macrophages in the Developing Lung Vasculature
    NIH R01HL155828Mar 5, 2021 - Feb 28, 2025
    Role: Principal Investigator
    Novel pathways regulating calcium mediated contractility in the pregnant uterus
    NIH R01HD092316Apr 1, 2018 - Mar 31, 2024
    Role: Principal Investigator
    Novel Molecular Mechanisms Regulating Postnatal Pulmonary Angiogenesis
    NIH R01HL122918May 2, 2014 - Apr 30, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Novel Netrin-1-Unc5b-Klf4 axis balances AT2 survival in experimental bronchopulmonary dysplasia. Am J Respir Cell Mol Biol. 2026 Mar 25. Klymenko O, Mohr J, Danopoulos S, Mižík I, Kuiper-Makris C, Stephan S, Mahjoub MA, Alvira CM, Rheindorf D, Imhof T, Akgül S, Donato M, Ebert LK, Müller S, Vohlen C, Hirani D, Bartenhagen C, Bartkuhn M, Procida T, Schermer B, Khatri P, Bellusci S, Goth K, Alexopoulos I, Georgomanolis T, Pryhuber GS, Pullamsetti SS, Seeger W, Al Alam D, Dötsch J, Koch M, Alejandre Alcazar MA. PMID: 42089296.
      View in: PubMed   Mentions:    Fields:    
    2. In the gravid human uterus, oxytocin induces smooth muscle cell contraction via transient receptor potential vanilloid 4 channel activation. J Physiol. 2026 04; 604(7):3135-3158. Fornes D, Ansari JR, Michel G, Alvira CM, Cornfield DN. PMID: 41762213.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Temporal and Spatial Gene Expression Dynamics in Neonatal HI Hippocampus with Focus on Arginase. Cells. 2026 Jan 28; 15(3). Smith MA, Natarajan E, Lizama-Valenzuela C, Arnold T, Stroud D, Larpthaveesarp A, Alvira C, Fineman JR, Ferriero DM, Maltepe E, Gonzalez F, Mike JK. PMID: 41677619; PMCID: PMC12896907.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. A Transcriptional Atlas of Endothelial Cell Zonation Along the Pulmonary Vascular Tree. bioRxiv. 2026 Jan 11. Sveiven SN, Knutsen C, Zanini F, Cornfield DN, Alvira CM. PMID: 41542612; PMCID: PMC12803053.
      View in: PubMed   Mentions:
    5. Postnatal Abrogation of VEGFR2 Blocks Terminal Cap2 Differentiation by Preventing the Developmental Progression from a Capillary Intermediate Cell State. bioRxiv. 2025 Nov 10. Zhang D, Knutsen C, Stroud DJ, Che X, Cornfield DN, Zanini F, Alvira CM. PMID: 40766488; PMCID: PMC12324266.
      View in: PubMed   Mentions:
    6. Yes-associated protein induces age-dependent inflammatory signaling in the pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol. 2025 09 01; 329(3):L315-L322. Emin MT, Dubuisson AM, Sujin Kumar P, Knutsen C, Alvira CM, Hough RF. PMID: 40707036; PMCID: PMC12358178.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Opportunity knocks: the fourth cohort of the American Journal of Physiology-Lung Cellular and Molecular Physiology Early Career Editorial Fellowship Program. Am J Physiol Lung Cell Mol Physiol. 2025 Sep 01; 329(3):L324-L326. Shimoda LA, Alvira CM, Bastarache JA, Britt RD, Knipe RS, Kuebler WM, Moreira TS, Schmidt EP. PMID: 40701621.
      View in: PubMed   Mentions:    Fields:    
    8. Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium. bioRxiv. 2025 May 16. Emin MT, Dubuisson AM, Kumar PS, Knutsen C, Alvira CM, Hough RF. PMID: 40196616; PMCID: PMC11974671.
      View in: PubMed   Mentions:
    9. Loss of TRPV4 decreases NFκB-mediated myometrial inflammation and prevents preterm labor. FASEB J. 2025 Feb 28; 39(4):e70418. Ingles JA, Rodriguez Z, Fornes D, Ying L, Han X, Cornfield DN, Alvira CM. PMID: 39989412.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. miR-203 modulates pregnant myometrium contractility via transient receptor potential vanilloid 4 channel expression. FASEB J. 2024 Nov; 38(22):e70173. Ying L, Fornes DD, Dobberfuhl AD, Ansari JR, Alvira CM, Cornfield DN. PMID: 39545721.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Pediatric subspecialty workforce: what is needed to secure its vitality and survival? Pediatr Res. 2025 Jun; 97(7):2208-2214. Dammann CE, Alvira CM, Devaskar SU, St Geme JW, Golden WC, Gordon CM, Hoffmann B, Lakshminrusimha S, Leslie LK, Trent M, Winer KK, Fromme HB. PMID: 39455858.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2024 Oct; 71(4):388-406. Hough RF, Alvira CM, Bastarache JA, Erzurum SC, Kuebler WM, Schmidt EP, Shimoda LA, Abman SH, Alvarez DF, Belvitch P, Bhattacharya J, Birukov KG, Chan SY, Cornfield DN, Dudek SM, Garcia JGN, Harrington EO, Hsia CCW, Islam MN, Jonigk DD, Kalinichenko VV, Kolb TM, Lee JY, Mammoto A, Mehta D, Rounds S, Schupp JC, Shaver CM, Suresh K, Tambe DT, Ventetuolo CE, Yoder MC, Stevens T, Damarla M. PMID: 39189891; PMCID: PMC11450313.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    13. Seeing pulmonary hypertension through a paediatric lens: a viewpoint. Eur Respir J. 2024 Jun; 63(6). Agarwal S, Fineman J, Cornfield DN, Alvira CM, Zamanian RT, Goss K, Yuan K, Bonnet S, Boucherat O, Pullamsetti S, Alcázar MA, Goncharova E, Kudryashova TV, Nicolls MR, de Jesús Pérez V. PMID: 38575157; PMCID: PMC11187317.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity. Sci Rep. 2024 01 23; 14(1):2033. Zanini F, Che X, Suresh NE, Knutsen C, Klavina P, Xie Y, Domingo-Gonzalez R, Liu M, Kum A, Jones RC, Quake SR, Alvira CM, Cornfield DN. PMID: 38263350; PMCID: PMC10805790.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. Integrative analysis of noncoding mutations identifies the druggable genome in preterm birth. Sci Adv. 2024 01 19; 10(3):eadk1057. Wang C, Wang YJ, Ying L, Wong RJ, Quaintance CC, Hong X, Neff N, Wang X, Biggio JR, Mesiano S, Quake SR, Alvira CM, Cornfield DN, Stevenson DK, Shaw GM, Li J. PMID: 38241369; PMCID: PMC10798565.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia. Inflamm Regen. 2023 Oct 24; 43(1):52. Hirani DV, Thielen F, Mansouri S, Danopoulos S, Vohlen C, Haznedar-Karakaya P, Mohr J, Wilke R, Selle J, Grosch T, Mizik I, Odenthal M, Alvira CM, Kuiper-Makris C, Pryhuber GS, Pallasch C, van Koningsbruggen-Rietschel S, Al-Alam D, Seeger W, Savai R, Dötsch J, Alejandre Alcazar MA. PMID: 37876024; PMCID: PMC10594718.
      View in: PubMed   Mentions: 17  
    17. Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2023 12 01; 325(6):L741-L755. Barnes EA, Ito R, Che X, Alvira CM, Cornfield DN. PMID: 37847687; PMCID: PMC11068430.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    18. Hypoxia-Inducible Factor-1α in SM22α-Expressing Cells Modulates Alveolarization. Am J Respir Cell Mol Biol. 2023 10; 69(4):470-483. Barnes EA, Knutsen C, Kindt A, Che X, Ying L, Adams E, Gonzalez E, Oak P, Hilgendorff A, Alvira CM, Cornfield DN. PMID: 37290124; PMCID: PMC10557922.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    19. Endothelial-specific loss of IKKβ disrupts pulmonary endothelial angiogenesis and impairs postnatal lung growth. Am J Physiol Lung Cell Mol Physiol. 2023 09 01; 325(3):L299-L313. Rao S, Liu M, Iosef C, Knutsen C, Alvira CM. PMID: 37310763; PMCID: PMC10625829.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    20. Wnt7a deficit is associated with dysfunctional angiogenesis in pulmonary arterial hypertension. Eur Respir J. 2023 06; 61(6). Chakraborty A, Nathan A, Orcholski M, Agarwal S, Shamskhou EA, Auer N, Mitra A, Guardado ES, Swaminathan G, Condon DF, Yu J, McCarra M, Juul NH, Mallory A, Guzman-Hernandez RA, Yuan K, Rojas V, Crossno JT, Yung LM, Yu PB, Spencer T, Winn RA, Frump A, Karoor V, Lahm T, Hedlin H, Fineman JR, Lafyatis R, Knutsen CNF, Alvira CM, Cornfield DN, de Jesus Perez VA. PMID: 37024132; PMCID: PMC10259331.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. Developmental diversity and unique sensitivity to injury of lung endothelial subtypes during postnatal growth. iScience. 2023 Mar 17; 26(3):106097. Zanini F, Che X, Knutsen C, Liu M, Suresh NE, Domingo-Gonzalez R, Dou SH, Zhang D, Pryhuber GS, Jones RC, Quake SR, Cornfield DN, Alvira CM. PMID: 36879800; PMCID: PMC9984561.
      View in: PubMed   Mentions: 18  
    22. SM22α cell-specific HIF stabilization mitigates hyperoxia-induced neonatal lung injury. Am J Physiol Lung Cell Mol Physiol. 2022 08 01; 323(2):L129-L141. Ito R, Barnes EA, Che X, Alvira CM, Cornfield DN. PMID: 35762602; PMCID: PMC9342196.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    23. Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia. Eur Respir J. 2022 02; 59(2). Hirani D, Alvira CM, Danopoulos S, Milla C, Donato M, Tian L, Mohr J, Dinger K, Vohlen C, Selle J, V Koningsbruggen-Rietschel S, Barbarino V, Pallasch C, Rose-John S, Odenthal M, Pryhuber GS, Mansouri S, Savai R, Seeger W, Khatri P, Al Alam D, Dötsch J, Alejandre Alcazar MA. PMID: 34446466; PMCID: PMC8850688.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    24. Dynamism of the Human Lung Proteome during Alveolarization: Moving beyond the Transcriptome. Am J Respir Crit Care Med. 2022 01 15; 205(2):145-147. Alvira CM. PMID: 34797738; PMCID: PMC8787247.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    25. Transforming Growth Factor-induced Protein Promotes NF-κB-mediated Angiogenesis during Postnatal Lung Development. Am J Respir Cell Mol Biol. 2021 03; 64(3):318-330. Liu M, Iosef C, Rao S, Domingo-Gonzalez R, Fu S, Snider P, Conway SJ, Umbach GS, Heilshorn SC, Dewi RE, Dahl MJ, Null DM, Albertine KH, Alvira CM. PMID: 33264084; PMCID: PMC7909333.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    26. Nanoparticle Delivery of Angiogenic Gene Therapy. Save the Vessels, Save the Lung! Am J Respir Crit Care Med. 2020 07 01; 202(1):13-14. Zepp JA, Alvira CM. PMID: 32338996; PMCID: PMC7328321.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung at single cell resolution. Elife. 2020 06 02; 9. Domingo-Gonzalez R, Zanini F, Che X, Liu M, Jones RC, Swift MA, Quake SR, Cornfield DN, Alvira CM. PMID: 32484158; PMCID: PMC7358008.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    28. NF-κB/NKILA signaling modulates the anti-cancerous effects of EZH2 inhibition. J Cell Mol Med. 2019 09; 23(9):6182-6192. Duan S, Chan WK, Oman A, Basile DP, Alvira CM, Buxton ILO, Iosef C. PMID: 31282094; PMCID: PMC6714229.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    29. Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success. J Pediatr. 2018 09; 200:277-284. Alvira CM, Steinhorn RH, Balistreri WF, Fineman JR, Oishi PE, Padbury JF, Kinsella JP, Abman SH. PMID: 30055815.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Distinct roles for IκB kinases alpha and beta in regulating pulmonary endothelial angiogenic function during late lung development. J Cell Mol Med. 2018 09; 22(9):4410-4422. Iosef C, Liu M, Ying L, Rao SP, Concepcion KR, Chan WK, Oman A, Alvira CM. PMID: 29993183; PMCID: PMC6111877.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    31. Pulmonary artery smooth muscle cell HIF-1α regulates endothelin expression via microRNA-543. Am J Physiol Lung Cell Mol Physiol. 2018 09 01; 315(3):L422-L431. Wang CC, Ying L, Barnes EA, Adams ES, Kim FY, Engel KW, Alvira CM, Cornfield DN. PMID: 29745253; PMCID: PMC6172620.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    32. Intrauterine growth restriction decreases NF-κB signaling in fetal pulmonary artery endothelial cells of fetal sheep. Am J Physiol Lung Cell Mol Physiol. 2018 09 01; 315(3):L348-L359. Dodson RB, Powers KN, Gien J, Rozance PJ, Seedorf G, Astling D, Jones K, Crombleholme TM, Abman SH, Alvira CM. PMID: 29722560; PMCID: PMC6172617.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    33. β1-Subunit of the calcium-sensitive potassium channel modulates the pulmonary vascular smooth muscle cell response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2018 08 01; 315(2):L265-L275. Barnes EA, Lee L, Barnes SL, Brenner R, Alvira CM, Cornfield DN. PMID: 29644895; PMCID: PMC6139656.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    34. Developmental differences in focal adhesion kinase expression modulate pulmonary endothelial barrier function in response to inflammation. Am J Physiol Lung Cell Mol Physiol. 2018 07 01; 315(1):L66-L77. Ying L, Alvira CM, Cornfield DN. PMID: 29597831; PMCID: PMC6087892.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    35. Can We Understand the Pathobiology of Bronchopulmonary Dysplasia? J Pediatr. 2017 11; 190:27-37. Alvira CM, Morty RE. PMID: 29144252; PMCID: PMC5726414.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    36. Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model. Physiol Rep. 2017 Apr; 5(8). Okamura H, Emrich F, Trojan J, Chiu P, Dalal AR, Arakawa M, Sato T, Penov K, Koyano T, Pedroza A, Connolly AJ, Rabinovitch M, Alvira C, Fischbein MP. PMID: 28455451; PMCID: PMC5408287.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    37. Aberrant Pulmonary Vascular Growth and Remodeling in Bronchopulmonary Dysplasia. Front Med (Lausanne). 2016; 3:21. Alvira CM. PMID: 27243014; PMCID: PMC4873491.
      View in: PubMed   Mentions: 53  
    38. Absence of TNF-α enhances inflammatory response in the newborn lung undergoing mechanical ventilation. Am J Physiol Lung Cell Mol Physiol. 2016 05 15; 310(10):L909-18. Ehrhardt H, Pritzke T, Oak P, Kossert M, Biebach L, Förster K, Koschlig M, Alvira CM, Hilgendorff A. PMID: 27016588; PMCID: PMC4896101.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    39. Loss of PPARγ in endothelial cells leads to impaired angiogenesis. J Cell Sci. 2016 Feb 15; 129(4):693-705. Vattulainen-Collanus S, Akinrinade O, Li M, Koskenvuo M, Li CG, Rao SP, de Jesus Perez V, Yuan K, Sawada H, Koskenvuo JW, Alvira C, Rabinovitch M, Alastalo TP. PMID: 26743080; PMCID: PMC5108588.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    40. The transient receptor potential vanilloid 4 channel modulates uterine tone during pregnancy. Sci Transl Med. 2015 Dec 23; 7(319):319ra204. Ying L, Becard M, Lyell D, Han X, Shortliffe L, Husted CI, Alvira CM, Cornfield DN. PMID: 26702092.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    41. Activation of the nuclear factor-κB pathway during postnatal lung inflammation preserves alveolarization by suppressing macrophage inflammatory protein-2. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15; 309(6):L593-604. Hou Y, Liu M, Husted C, Chen C, Thiagarajan K, Johns JL, Rao SP, Alvira CM. PMID: 26163511; PMCID: PMC4572419.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    42. Pulmonary artery smooth muscle cell endothelin-1 expression modulates the pulmonary vascular response to chronic hypoxia. Am J Physiol Lung Cell Mol Physiol. 2015 Feb 15; 308(4):L368-77. Kim FY, Barnes EA, Ying L, Chen C, Lee L, Alvira CM, Cornfield DN. PMID: 25399435; PMCID: PMC4329469.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    43. Enhanced caspase activity contributes to aortic wall remodeling and early aneurysm development in a murine model of Marfan syndrome. Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1):146-54. Emrich FC, Okamura H, Dalal AR, Penov K, Merk DR, Raaz U, Hennigs JK, Chin JT, Miller MO, Pedroza AJ, Craig JK, Koyano TK, Blankenberg FG, Connolly AJ, Mohr FW, Alvira CM, Rabinovitch M, Fischbein MP. PMID: 25359856.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    44. Haemophagocytic lymphohistiocytosis associated with coccidiomycosis. BMJ Case Rep. 2014 Aug 19; 2014. Ramsi M, Alvira C, Purohit P, Cornfield D. PMID: 25139924; PMCID: PMC4139546.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    45. Disrupted lung development and bronchopulmonary dysplasia: opportunities for lung repair and regeneration. Curr Opin Pediatr. 2014 Jun; 26(3):306-14. Baker CD, Alvira CM. PMID: 24739494; PMCID: PMC4121955.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    46. Nuclear factor-kappa-B signaling in lung development and disease: one pathway, numerous functions. Birth Defects Res A Clin Mol Teratol. 2014 Mar; 100(3):202-16. Alvira CM. PMID: 24639404; PMCID: PMC4158903.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    47. Chronic lung disease in the preterm infant. Lessons learned from animal models. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):233-45. Hilgendorff A, Reiss I, Ehrhardt H, Eickelberg O, Alvira CM. PMID: 24024524; PMCID: PMC5455410.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimals
    48. Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation. Circ Res. 2013 Apr 26; 112(9):1230-3. Kim YM, Barnes EA, Alvira CM, Ying L, Reddy S, Cornfield DN. PMID: 23513056; PMCID: PMC4005857.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    49. Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production. Am J Respir Cell Mol Biol. 2012 Nov; 47(5):669-78. Alvira CM, Umesh A, Husted C, Ying L, Hou Y, Lyu SC, Nowak J, Cornfield DN. PMID: 22842492; PMCID: PMC3547107.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    50. Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization. Am J Physiol Lung Cell Mol Physiol. 2012 May 15; 302(10):L1023-36. Iosef C, Alastalo TP, Hou Y, Chen C, Adams ES, Lyu SC, Cornfield DN, Alvira CM. PMID: 22367785; PMCID: PMC3362264.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    51. Hypoxia-inducible factor-1α regulates KCNMB1 expression in human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 01; 302(3):L352-9. Ahn YT, Kim YM, Adams E, Lyu SC, Alvira CM, Cornfield DN. PMID: 22114151; PMCID: PMC3289270.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    52. miR-29b participates in early aneurysm development in Marfan syndrome. Circ Res. 2012 Jan 20; 110(2):312-24. Merk DR, Chin JT, Dake BA, Maegdefessel L, Miller MO, Kimura N, Tsao PS, Iosef C, Berry GJ, Mohr FW, Spin JM, Alvira CM, Robbins RC, Fischbein MP. PMID: 22116819.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    53. Neutrophil elastase is produced by pulmonary artery smooth muscle cells and is linked to neointimal lesions. Am J Pathol. 2011 Sep; 179(3):1560-72. Kim YM, Haghighat L, Spiekerkoetter E, Sawada H, Alvira CM, Wang L, Acharya S, Rodriguez-Colon G, Orton A, Zhao M, Rabinovitch M. PMID: 21763677; PMCID: PMC3157285.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    54. Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki disease. Am J Pathol. 2011 Mar; 178(3):1210-20. Alvira CM, Guignabert C, Kim YM, Chen C, Wang L, Duong TT, Yeung RS, Li DY, Rabinovitch M. PMID: 21356372; PMCID: PMC3070551.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    55. Rho kinase modulates postnatal adaptation of the pulmonary circulation through separate effects on pulmonary artery endothelial and smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2010 Dec; 299(6):L872-8. Alvira CM, Sukovich DJ, Lyu SC, Cornfield DN. PMID: 20709731; PMCID: PMC3006275.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    56. Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice. Am J Physiol Lung Cell Mol Physiol. 2010 Jan; 298(1):L23-35. Mokres LM, Parai K, Hilgendorff A, Ertsey R, Alvira CM, Rabinovitch M, Bland RD. PMID: 19854954; PMCID: PMC2806196.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    57. Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization. Am J Physiol Lung Cell Mol Physiol. 2009 Dec; 297(6):L1082-90. Guignabert C, Alvira CM, Alastalo TP, Sawada H, Hansmann G, Zhao M, Wang L, El-Bizri N, Rabinovitch M. PMID: 19801450; PMCID: PMC2793182.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    58. LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor. J Cell Sci. 2009 May 01; 122(Pt 9):1441-51. Ying L, Lau A, Alvira CM, West R, Cann GM, Zhou B, Kinnear C, Jan E, Sarnow P, Van de Rijn M, Rabinovitch M. PMID: 19366727; PMCID: PMC2672968.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    59. An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension. J Clin Invest. 2008 May; 118(5):1846-57. Hansmann G, de Jesus Perez VA, Alastalo TP, Alvira CM, Guignabert C, Bekker JM, Schellong S, Urashima T, Wang L, Morrell NW, Rabinovitch M. PMID: 18382765; PMCID: PMC2276393.
      View in: PubMed   Mentions: 228     Fields:    Translation:HumansAnimalsCells
    60. Reactivation of gammaHV68 induces neointimal lesions in pulmonary arteries of S100A4/Mts1-overexpressing mice in association with degradation of elastin. Am J Physiol Lung Cell Mol Physiol. 2008 Feb; 294(2):L276-89. Spiekerkoetter E, Alvira CM, Kim YM, Bruneau A, Pricola KL, Wang L, Ambartsumian N, Rabinovitch M. PMID: 18083765.
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    61. Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis in lungs of newborn mice. Prelude to defective alveolar septation during lung development? Am J Physiol Lung Cell Mol Physiol. 2008 Jan; 294(1):L3-14. Bland RD, Ertsey R, Mokres LM, Xu L, Jacobson BE, Jiang S, Alvira CM, Rabinovitch M, Shinwell ES, Dixit A. PMID: 17934062.
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    62. Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation. Am J Respir Crit Care Med. 2007 Apr 15; 175(8):805-15. Alvira CM, Abate A, Yang G, Dennery PA, Rabinovitch M. PMID: 17255561; PMCID: PMC1899293.
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