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Actigraphy Study Endpoints to Reduce Sample Size and Facilitate Drug Development for Pediatric Pulmonary Arterial Hypertension. J Pediatr. 2024 Nov 01; 114383.
Sun H, Stockbridge N, Ivy DD, Clark J, Bates A, Handler SS, Krishnan US, Mullen MP, Yung D, Hopper RK, Varghese NP, Avitabile CM, Fineman J, Austin ED, Freire G. PMID: 39489285.
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Perinatal Caffeine Administration Improves Outcomes in an Ovine Model of Neonatal Hypoxia-Ischemia. Stroke. 2024 Oct 21.
Mike JK, White Y, Ha J, Iranmahboub A, Hawkins C, Hutchings RS, Vento C, Manzoor H, Wang A, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Fineman JR, Ferriero DM, Maltepe E. PMID: 39429154.
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Translation:
Animals
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A Multi-Chamber Pulsating-Flow Device with Optimized Spatial Shear Stress and Pressure for Endothelial-Cell Testing. J Biomech Eng. 2024 Oct 09; 1-13.
Campos O, Garcia De Herreros A, Sánchez A, Fineman JR, Pawlak G. PMID: 39382480.
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HumansCells
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Inhalable Advanced Co-Spray Dried Microparticles/Nanoparticles of a Novel RhoA/Rho Kinase Inhibitor with Lung Surfactant Biomimetic Phospholipids for Targeted Lung Delivery. ACS Pharmacol Transl Sci. 2024 Oct 11; 7(10):3241-3254.
Ruiz VH, Encinas-Basurto D, Ortega-Alarcon N, Eedara BB, Fineman JR, Black SM, Mansour HM. PMID: 39416970; PMCID: PMC11475283.
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The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status. Nitric Oxide. 2024 Nov 01; 152:90-100.
Sun X, Moreno Caceres S, Yegambaram M, Lu Q, Pokharel MD, Boehme JT, Datar SA, Aggarwal S, Wang T, Fineman JR, Black SM. PMID: 39332480.
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HumansAnimalsCells
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Design and comprehensive characterization of dry powder inhalation aerosols of simvastatin DPPC/DPPG lung surfactant-mimic nanoparticles/microparticles for pulmonary nanomedicine. RSC Adv. 2024 Sep 12; 14(40):29413-29427.
Encinas-Basurto D, Acosta MF, Eedara BB, Fineman JR, Black SM, Mansour HM. PMID: 39285876; PMCID: PMC11404307.
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Seeing pulmonary hypertension through a paediatric lens: a viewpoint. Eur Respir J. 2024 Jun; 63(6).
Agarwal S, Fineman J, Cornfield DN, Alvira CM, Zamanian RT, Goss K, Yuan K, Bonnet S, Boucherat O, Pullamsetti S, Alcázar MA, Goncharova E, Kudryashova TV, Nicolls MR, de Jesús Pérez V. PMID: 38575157; PMCID: PMC11187317.
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Translation:
Humans
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Pre-eclampsia and barker's hypothesis: are we beginning to see the trees within the forest? Pediatr Res. 2024 Sep; 96(4):826-827.
Tsoi SM, Steurer M, Maltepe E, Fineman JR. PMID: 38822134; PMCID: PMC11502483.
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Defining the Typical Course of Persistent Pulmonary Hypertension of the Newborn: When to Think Beyond Reversible Causes. J Pediatr. 2024 Oct; 273:114131.
Tsoi SM, Steurer M, Nawaytou H, Cheung S, Keller RL, Fineman JR. PMID: 38823627.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Pulmonary hypertension in the intensive care unit after pediatric allogeneic hematopoietic stem cell transplant: incidence, risk factors, and outcomes. Front Oncol. 2024; 14:1415984.
Smith MA, Cheng G, Phelan R, Brazauskas R, Strom J, Ahn KW, Hamilton BK, Peterson A, Savani B, Schoemans H, Schoettler ML, Sorror M, Keller RL, Higham CS, Dvorak CC, Fineman JR, Zinter MS. PMID: 38868534; PMCID: PMC11167102.
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Management of pulmonary vascular disease associated with congenital left-to-right shunts: A single-center experience. J Thorac Cardiovasc Surg. 2024 May 18.
Nawaytou H, Lakkaraju R, Stevens L, Reddy VM, Swami N, Keller RL, Teitel DF, Fineman JR. PMID: 38763305.
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1 Fields:
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Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling. Free Radic Biol Med. 2024 Aug 20; 221:125-135.
Pokharel MD, Fu P, Garcia-Flores A, Yegambaram M, Lu Q, Sun X, Unwalla H, Aggarwal S, Fineman JR, Wang T, Black SM. PMID: 38734269; PMCID: PMC11179967.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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OMX: A NOVEL OXYGEN DELIVERY BIOTHERAPEUTIC IMPROVES OUTCOMES IN AN OVINE MODEL OF CONTROLLED HEMORRHAGIC SHOCK. Shock. 2024 Jul 01; 62(1):103-110.
Maltepe E, Smith M, Boehme J, Datar SA, Hutchings RS, Vento CA, Manzoor H, Loucks A, Winger JA, Fineman JR. PMID: 38662597.
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Animals
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A single institution anesthetic experience with catheterization of pediatric pulmonary hypertension patients. Pulm Circ. 2024 Apr; 14(2):e12360.
Morell E, Colglazier E, Becerra J, Stevens L, Steurer MA, Sharma A, Nguyen H, Kathiriya IS, Weston S, Teitel D, Keller R, Amin EK, Nawaytou H, Fineman JR. PMID: 38618291; PMCID: PMC11010955.
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PubMed Mentions:
1
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Actigraphy methodology in the Kids Mod PAH trial: Physical activity as a functional endpoint in pediatric clinical trials. Pulm Circ. 2024 Jan; 14(1):e12339.
Avitabile CM, Krishnan US, Yung D, Handler SS, Varghese N, Bates A, Fineman J, Sullivan R, Friere G, Austin E, Mullen MP, Pereira C, Christensen EJ, Yenokyan G, Collaco JM, Abman SH, Romer L, Dunbar Ivy D, Rosenzweig EB. PMID: 38464344; PMCID: PMC10923039.
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PubMed Mentions:
2
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Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics. Redox Biol. 2024 04; 70:103049.
Pokharel MD, Garcia-Flores A, Marciano D, Franco MC, Fineman JR, Aggarwal S, Wang T, Black SM. PMID: 38295575; PMCID: PMC10844980.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Novel Relationship between Mitofusin 2-Mediated Mitochondrial Hyperfusion, Metabolic Remodeling, and Glycolysis in Pulmonary Arterial Endothelial Cells. Int J Mol Sci. 2023 Dec 15; 24(24).
Yegambaram M, Sun X, Flores AG, Lu Q, Soto J, Richards J, Aggarwal S, Wang T, Gu H, Fineman JR, Black SM. PMID: 38139362; PMCID: PMC10744129.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation. Nitric Oxide. 2024 Jan 01; 142:58-68.
Boehme JT, Sun X, Lu Q, Barton J, Wu X, Gong W, Raff GW, Datar SA, Wang T, Fineman JR, Black SM. PMID: 38061411; PMCID: PMC11045265.
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HumansAnimalsCells
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View in:
PubMed Mentions: Fields:
Translation:
Humans
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Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III. Free Radic Biol Med. 2024 01; 210:183-194.
Yegambaram M, Sun X, Lu Q, Jin Y, Ornatowski W, Soto J, Aggarwal S, Wang T, Tieu K, Gu H, Fineman JR, Black SM. PMID: 37979892.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Kids Mod PAH trial: A multicenter trial comparing mono- versus duo-therapy for initial treatment of pediatric pulmonary hypertension. Pulm Circ. 2023 Oct; 13(4):e12305.
Collaco JM, Abman SH, Austin ED, Avitabile CM, Bates A, Fineman JR, Freire GA, Handler SS, Ivy DD, Krishnan US, Mullen MP, Varghese NP, Yung D, Nies MK, Everett AD, Zimmerman KO, Simmons W, Chakraborty H, Yenokyan G, Newell-Sturdivant A, Christensen E, Eyzaguirre LM, Hanley DF, Rosenzweig EB, Romer LH. PMID: 37915400; PMCID: PMC10617301.
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PubMed Mentions:
4
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Effect of Clemastine on Neurophysiological Outcomes in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy. Children (Basel). 2023 Oct 25; 10(11).
Mike JK, White Y, Hutchings RS, Vento C, Ha J, Iranmahboub A, Manzoor H, Gunewardena A, Cheah C, Wang A, Goudy BD, Lakshminrusimha S, Long-Boyle J, Fineman JR, Ferriero DM, Maltepe E. PMID: 38002819; PMCID: PMC10670092.
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PubMed Mentions:
4
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Perinatal Azithromycin Provides Limited Neuroprotection in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy. Stroke. 2023 11; 54(11):2864-2874.
Mike JK, White Y, Hutchings RS, Vento C, Ha J, Manzoor H, Lee D, Losser C, Arellano K, Vanhatalo O, Seifert E, Gunewardena A, Wen B, Wang L, Wang A, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Wu YW, Fineman JR, Ferriero DM, Maltepe E. PMID: 37846563; PMCID: PMC10589434.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Safety and tolerability of continuous inhaled iloprost in critically ill pediatric pulmonary hypertension patients: A retrospective case series. Pulm Circ. 2023 Jul; 13(3):e12289.
Colglazier E, Ng AJ, Parker C, Woolsey D, Holmes R, Dsouza A, Becerra J, Stevens L, Nawaytou H, Keller RL, Fineman JR. PMID: 37731624; PMCID: PMC10507570.
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PubMed Mentions:
2
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Endothelin-1 acutely increases nitric oxide production via the calcineurin mediated dephosphorylation of Caveolin-1. Nitric Oxide. 2023 Nov 01; 140-141:50-57.
Yegambaram M, Kumar S, Wu X, Lu Q, Sun X, Garcia Flores A, Meadows ML, Barman S, Fulton D, Wang T, Fineman JR, Black SM. PMID: 37659679.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Associated radiation exposure from medical imaging and excess lifetime risk of developing cancer in pediatric patients with pulmonary hypertension. Pulm Circ. 2023 Jul; 13(3):e12282.
Mahendra M, Chu P, Amin EK, Nawaytou H, Duncan JR, Fineman JR, Smith-Bindman R. PMID: 37614831; PMCID: PMC10442605.
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PubMed Mentions:
2
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Measurement of Physical Activity by Actigraphy in Infants and Young Children with Pulmonary Arterial Hypertension. J Pediatr. 2023 11; 262:113639.
Avitabile CM, Yung D, Handler S, Hopper RK, Fineman J, Freire G, Varghese N, Mullen MP, Krishnan US, Austin E, Silveira L, Ivy DD. PMID: 37517653; PMCID: PMC11164018.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Metabolic reprogramming, oxidative stress, and pulmonary hypertension. Redox Biol. 2023 08; 64:102797.
Pokharel MD, Marciano DP, Fu P, Franco MC, Unwalla H, Tieu K, Fineman JR, Wang T, Black SM. PMID: 37392518; PMCID: PMC10363484.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Respiratory mechanics and gas exchange in an ovine model of congenital heart disease with increased pulmonary blood flow and pressure. Front Physiol. 2023; 14:1188824.
Soares JHN, Raff GW, Fineman JR, Datar SA. PMID: 37362431; PMCID: PMC10288580.
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Wnt7a deficit is associated with dysfunctional angiogenesis in pulmonary arterial hypertension. Eur Respir J. 2023 06; 61(6).
Chakraborty A, Nathan A, Orcholski M, Agarwal S, Shamskhou EA, Auer N, Mitra A, Guardado ES, Swaminathan G, Condon DF, Yu J, McCarra M, Juul NH, Mallory A, Guzman-Hernandez RA, Yuan K, Rojas V, Crossno JT, Yung LM, Yu PB, Spencer T, Winn RA, Frump A, Karoor V, Lahm T, Hedlin H, Fineman JR, Lafyatis R, Knutsen CNF, Alvira CM, Cornfield DN, de Jesus Perez VA. PMID: 37024132; PMCID: PMC10259331.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission. J Biol Chem. 2023 04; 299(4):103067.
Lu Q, Sun X, Yegambaram M, Ornatowski W, Wu X, Wang H, Garcia-Flores A, Da Silva V, Zemskov EA, Tang H, Fineman JR, Tieu K, Wang T, Black SM. PMID: 36841483; PMCID: PMC10060112.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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PubMed Mentions:
2
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Predictability and stability testing to assess clinical decision instrument performance for children after blunt torso trauma. PLOS Digit Health. 2022 Aug; 1(8):e0000076.
Kornblith AE, Singh C, Devlin G, Addo N, Streck CJ, Holmes JF, Kuppermann N, Grupp-Phelan J, Fineman J, Butte AJ, Yu B. PMID: 36812570; PMCID: PMC9931266.
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PubMed Mentions:
1
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Caveolin-1 associated with severe (pediatric-onset) presentation of pulmonary arterial hypertension. Pulm Circ. 2022 Jul; 12(3):e12100.
Farrell R, Colglazier E, Parker C, Stevens L, Austin ED, Fineman JR. PMID: 35864912; PMCID: PMC9294289.
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PubMed Mentions:
3
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View in:
PubMed Mentions:
4
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Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension. Ann Am Thorac Soc. 2022 06; 19(6):1000-1012.
Rosenzweig EB, Bates A, Mullen MP, Abman SH, Austin ED, Everett A, Fineman J, Feinstein J, Hopper RK, Kinsella JP, Krishnan US, Lu M, Mandl KD, Raj JU, Varghese N, Yung D, Handler SS, Sleeper LA. PMID: 35049414; PMCID: PMC9169121.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Progress in Pulmonary Vein Stenosis: Lessons from Success in Treating Pulmonary Arterial Hypertension. Children (Basel). 2022 May 29; 9(6).
Jenkins KJ, Fineman JR. PMID: 35740736; PMCID: PMC9222029.
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PubMed Mentions:
1
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Defining Longer-Term Outcomes in an Ovine Model of Moderate Perinatal Hypoxia-Ischemia. Dev Neurosci. 2022; 44(4-5):277-294.
Mike JK, Wu KY, White Y, Pathipati P, Ndjamen B, Hutchings RS, Losser C, Vento C, Arellano K, Vanhatalo O, Ostrin S, Windsor C, Ha J, Alhassen Z, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Chen P, Wu YW, Fineman JR, Ferriero DM, Maltepe E. PMID: 35588703; PMCID: PMC9474697.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2022 May 16; 132(10).
Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. PMID: 35575096; PMCID: PMC9106337.
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PubMed Mentions:
3 Fields:
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Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network. Pulm Circ. 2022 Jan; 12(1):e12031.
Handler SS, Varghese NP, Rosenzweig EB, Yung D, Krishnan U, Whalen E, Bates A, Avitabile CM, Jackson EO, Hirsch R, Fineman J, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet). PMID: 35506071; PMCID: PMC9052968.
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PubMed Mentions:
1
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PubMed Mentions:
3
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Characterisation of paediatric pulmonary hypertensive vascular disease from the PPHNet Registry. Eur Respir J. 2022 01; 59(1).
Abman SH, Mullen MP, Sleeper LA, Austin ED, Rosenzweig EB, Kinsella JP, Ivy D, Hopper RK, Raj JU, Fineman J, Keller RL, Bates A, Krishnan US, Avitabile CM, Davidson A, Natter MD, Mandl KD, Pediatric Pulmonary Hypertension Network. PMID: 34140292; PMCID: PMC10335325.
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32 Fields:
Translation:
Humans
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Advanced Microparticulate/Nanoparticulate Respirable Dry Powders of a Selective RhoA/Rho Kinase (Rock) Inhibitor for Targeted Pulmonary Inhalation Aerosol Delivery. Pharmaceutics. 2021 Dec 17; 13(12).
Muralidharan P, Hayes D, Fineman JR, Black SM, Mansour HM. PMID: 34959469; PMCID: PMC8707591.
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PubMed Mentions:
2
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Insights into the impact of sections and departments on your career: The APS-SPR Virtual Chat Series. Pediatr Res. 2022 09; 92(3):662-670.
Davis SD, Fineman JR, St Geme Iii JW. PMID: 34824399; PMCID: PMC8614070.
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1 Fields:
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Biallelic variants of ATP13A3 cause dose-dependent childhood-onset pulmonary arterial hypertension characterised by extreme morbidity and mortality. J Med Genet. 2022 Sep; 59(9):906-911.
Machado RD, Welch CL, Haimel M, Bleda M, Colglazier E, Coulson JD, Debeljak M, Ekstein J, Fineman JR, Golden WC, Griffin EL, Hadinnapola C, Harris MA, Hirsch Y, Hoover-Fong JE, Nogee L, Romer LH, Vesel S, NIHR Bioresource – Rare Diseases, Gräf S, Morrell NW, Southgate L, Chung WK. PMID: 34493544; PMCID: PMC9411922.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Mortality from Pulmonary Hypertension in the Pediatric Cardiac ICU. Am J Respir Crit Care Med. 2021 08 15; 204(4):454-461.
Morell E, Gaies M, Fineman JR, Charpie J, Rao R, Sasaki J, Zhang W, Reichle G, Banerjee M, Tabbutt S. PMID: 33798036.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Safety and Tolerability of a Rapid Transition From Intravenous Treprostinil to Oral Selexipag in Three Adolescent Patients With Pulmonary Arterial Hypertension. J Pediatr Pharmacol Ther. 2021; 26(5):512-516.
Colglazier E, Ng AJ, Parker C, Nawaytou H, Fineman JR. PMID: 34239406; PMCID: PMC8244952.
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PubMed Mentions:
2
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Monitoring deep-tissue oxygenation with a millimeter-scale ultrasonic implant. Nat Biotechnol. 2021 07; 39(7):855-864.
Sonmezoglu S, Fineman JR, Maltepe E, Maharbiz MM. PMID: 33782610.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Pulmonary Arteriovenous Malformations and the Hepatic "Black Box": Are We Emerging From the Darkness? JACC Basic Transl Sci. 2021 Mar; 6(3):236-238.
Rajagopal SK, Fineman JR. PMID: 33779631; PMCID: PMC7987538.
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PubMed Mentions:
2
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Practice patterns of pulmonary hypertension secondary to left heart disease among pediatric pulmonary hypertension providers. Pulm Circ. 2021 Jan-Mar; 11(1):2045894021991446.
Nawaytou H, Fineman JR, Moledina S, Ivy D, Abman SH, Cerro MJD. PMID: 33623667; PMCID: PMC7879002.
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PubMed Mentions:
1
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Comparison of l-Carnitine and l-Carnitine HCL salt for targeted lung treatment of pulmonary hypertension (PH) as inhalation aerosols: Design, comprehensive characterization, in vitro 2D/3D cell cultures, and in vivo MCT-Rat model of PH. Pulm Pharmacol Ther. 2020 12; 65:101998.
Acosta MF, Muralidhran P, Abrahamson MD, Grijalva CL, Carver M, Tang H, Klinger C, Fineman JR, Black SM, Mansour HM. PMID: 33556627; PMCID: PMC8985976.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow. Sci Rep. 2021 01 14; 11(1):1468.
Boehme JT, Morris CJ, Chiacchia SR, Gong W, Wu KY, Kameny RJ, Raff GW, Fineman JR, Maltepe E, Datar SA. PMID: 33446832; PMCID: PMC7809484.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Advanced therapeutic inhalation aerosols of a Nrf2 activator and RhoA/Rho kinase (ROCK) inhibitor for targeted pulmonary drug delivery in pulmonary hypertension: design, characterization, aerosolization, in vitro 2D/3D human lung cell cultures, and in vivo efficacy. Ther Adv Respir Dis. 2021 Jan-Dec; 15:1753466621998245.
Acosta MF, Muralidharan P, Grijalva CL, Abrahamson MD, Hayes D, Fineman JR, Black SM, Mansour HM. PMID: 33719747; PMCID: PMC7968029.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system. Nitric Oxide. 2021 03 01; 108:12-19.
Wu X, Sun X, Sharma S, Lu Q, Yegambaram M, Hou Y, Wang T, Fineman JR, Black SM. PMID: 33338599; PMCID: PMC8193791.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Novel Documentation of Onset and Rapid Advancement of Pulmonary Arterial Hypertension without Symptoms in BMPR2 Mutation Carriers: Cautionary Tales? Am J Respir Crit Care Med. 2020 12 01; 202(11):1587-1589.
Amin EK, Austin ED, Parker C, Colglazier E, Nawaytou H, Leary PJ, Hemnes AR, Teitel D, Fineman JR. PMID: 32692583.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder Inhalers. AAPS J. 2020 11 16; 23(1):2.
Acosta MF, Abrahamson MD, Encinas-Basurto D, Fineman JR, Black SM, Mansour HM. PMID: 33200330; PMCID: PMC7669792.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics. Redox Biol. 2021 01; 38:101785.
Lu Q, Zemskov EA, Sun X, Wang H, Yegambaram M, Wu X, Garcia-Flores A, Song S, Tang H, Kangath A, Cabanillas GZ, Yuan JX, Wang T, Fineman JR, Black SM. PMID: 33221570; PMCID: PMC7691184.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Complex interplay between autophagy and oxidative stress in the development of pulmonary disease. Redox Biol. 2020 09; 36:101679.
Ornatowski W, Lu Q, Yegambaram M, Garcia AE, Zemskov EA, Maltepe E, Fineman JR, Wang T, Black SM. PMID: 32818797; PMCID: PMC7451718.
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PubMed Mentions:
126 Fields:
Translation:
AnimalsCells
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Pharmacokinetics of Oral Treprostinil in Children With Pulmonary Arterial Hypertension. J Cardiovasc Pharmacol. 2020 07; 76(1):94-100.
Hopper RK, Ivy DD, Yung D, Mullen MP, Hanna BD, Kirkpatrick E, Hirsch R, Austin ED, Fineman J, Solum D, Deng CQ, Feinstein JA. PMID: 32398473.
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PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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The many faces and outcomes of pulmonary vein stenosis in early childhood. Pediatr Pulmonol. 2021 03; 56(3):649-655.
Humpl T, Fineman J, Qureshi AM. PMID: 32506838.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Equipoise and Acumen in Pediatric Acute Respiratory Distress Syndrome Research. Am J Respir Crit Care Med. 2020 06 01; 201(11):1326-1327.
Oishi P, Fineman JR. PMID: 32271615; PMCID: PMC7258640.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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TGF-β1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis. Redox Biol. 2020 09; 36:101593.
Sun X, Lu Q, Yegambaram M, Kumar S, Qu N, Srivastava A, Wang T, Fineman JR, Black SM. PMID: 32554303; PMCID: PMC7303661.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease. Pulm Circ. 2020 Apr-Jun; 10(2):2045894020922118.
Zhu T, Chiacchia S, Kameny RJ, Garcia De Herreros A, Gong W, Raff GW, Boehme JB, Maltepe E, Lasheras JC, Black SM, Datar SA, Fineman JR. PMID: 32489641; PMCID: PMC7238833.
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PubMed Mentions:
1
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Extracorporeal Membrane Oxygenation in Pediatric Pulmonary Hypertension. Pediatr Crit Care Med. 2020 03; 21(3):256-266.
Morell E, Rajagopal SK, Oishi P, Thiagarajan RR, Fineman JR, Steurer MA. PMID: 31577693.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Clinical Utility of Echocardiography in Former Preterm Infants with Bronchopulmonary Dysplasia. J Am Soc Echocardiogr. 2020 03; 33(3):378-388.e1.
Nawaytou H, Steurer MA, Zhao Y, Guslits E, Teitel D, Fineman JR, Keller RL. PMID: 31948712.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Outcomes of pulmonary vascular disease in infants conceived with non-IVF fertility treatment and assisted reproductive technologies at 1 year of age. Pediatr Pulmonol. 2019 11; 54(11):1844-1852.
Fineman DC, Baer RJ, Chambers CD, Rajagopal S, Maltepe E, Rinaudo PF, Fineman JR, Jelliffe-Pawlowski LL, Steurer MA. PMID: 31328432.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Oral treprostinil in transition or as add-on therapy in pediatric pulmonary arterial hypertension. Pulm Circ. 2019 Jul-Sep; 9(3):2045894019856471.
Ivy DD, Feinstein JA, Yung D, Mullen MP, Kirkpatrick EC, Hirsch R, Austin ED, Fineman J, Truong U, Solum D, Deng CQ, Hopper RK. PMID: 31215336; PMCID: PMC6628532.
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PubMed Mentions:
5
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EXPRESS: Acute Vasoreactivity Testing in Pediatric Idiopathic Pulmonary Arterial Hypertension: an international Survey on Current Practice. Pulm Circ. 2019 May 30; 2045894019857533.
Caicedo L, Hopper RK, Garcia H, Ivy DD, Haag D, Fineman J, Humpi T, Al-Tamimi O, Feinstein J, Berger RM, Berman-Rosenzweig E, Kashour T, Diaz GF, Mendoza A, Bobhate P, Handler S, Lopes AA, Barwad P, Kumar Rahit M, Krishnan U, Adatia ITK, Moledina S, Abman S, Cerro Marin MJD. PMID: 31144586; PMCID: PMC6886286.
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PubMed Mentions:
6
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Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling. Am J Respir Cell Mol Biol. 2019 05; 60(5):503-514.
Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR. PMID: 30620615; PMCID: PMC6503613.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Pulmonary Endothelial Mechanical Sensing and Signaling, a Story of Focal Adhesions and Integrins in Ventilator Induced Lung Injury. Front Physiol. 2019; 10:511.
Kelly GT, Faraj R, Zhang Y, Maltepe E, Fineman JR, Black SM, Wang T. PMID: 31105595; PMCID: PMC6498899.
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PubMed Mentions:
9
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View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Biomechanical Forces and Oxidative Stress: Implications for Pulmonary Vascular Disease. Antioxid Redox Signal. 2019 10 20; 31(12):819-842.
Zemskov EA, Lu Q, Ornatowski W, Klinger CN, Desai AA, Maltepe E, Yuan JX, Wang T, Fineman JR, Black SM. PMID: 30623676; PMCID: PMC6751394.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. PLoS Biol. 2019 Jan; 17(1):e3000119.
Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, Krtolica A, Maltepe E. PMID: 30677022; PMCID: PMC6345423.
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PubMed Mentions:
1 Fields:
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Two patients with FOXF1 mutations with alveolar capillary dysplasia with misalignment of pulmonary veins and other malformations: Two different presentations and outcomes. Am J Med Genet A. 2018 12; 176(12):2877-2881.
Abu-El-Haija A, Fineman J, Connolly AJ, Murali P, Judge LM, Slavotinek AM. PMID: 30380203.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. PLoS Biol. 2018 10; 16(10):e2005924.
Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, Krtolica A, Maltepe E. PMID: 30335746; PMCID: PMC6193608.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success. J Pediatr. 2018 09; 200:277-284.
Alvira CM, Steinhorn RH, Balistreri WF, Fineman JR, Oishi PE, Padbury JF, Kinsella JP, Abman SH. PMID: 30055815.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Analysis of the microRNA signature driving adaptive right ventricular hypertrophy in an ovine model of congenital heart disease. Am J Physiol Heart Circ Physiol. 2018 10 01; 315(4):H847-H854.
Kameny RJ, He Y, Zhu T, Gong W, Raff GW, Chapin CJ, Datar SA, Boehme JT, Hata A, Fineman JR. PMID: 29906222; PMCID: PMC6230913.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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KLF2-mediated disruption of PPAR-γ signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow. Am J Physiol Heart Circ Physiol. 2018 07 01; 315(1):H173-H181.
Morris CJ, Kameny RJ, Boehme J, Gong W, He Y, Zhu T, Maltepe E, Raff GW, Fineman JR, Datar SA. PMID: 29631374; PMCID: PMC6087778.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension. J Pediatr. 2018 06; 197:17-22.
Kinsella JP, Steinhorn RH, Mullen MP, Hopper RK, Keller RL, Ivy DD, Austin ED, Krishnan US, Rosenzweig EB, Fineman JR, Everett AD, Hanna BD, Humpl T, Raj JU, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet). PMID: 29628412.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Safety, efficacy and Management of subcutaneous treprostinil infusions in the treatment of severe pediatric pulmonary hypertension. Int J Cardiol. 2018 08 01; 264:153-157.
Levy M, Del Cerro MJ, Nadaud S, Vadlamudi K, Colgazier E, Fineman J, Bonnet D, Adatia I. PMID: 29650343.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Multicenter mortality and morbidity associated with pulmonary hypertension in the pediatric intensive care unit. Pulm Circ. 2018 Jan-Mar; 8(1):2045893217745785.
Balkin EM, Steurer MA, Delagnes EA, Zinter MS, Rajagopal S, Keller RL, Fineman JR. PMID: 29251545; PMCID: PMC5753928.
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PubMed Mentions:
8
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Altered Carnitine Homeostasis in Children With Increased Pulmonary Blood Flow Due to Ventricular Septal Defects. Pediatr Crit Care Med. 2017 Oct; 18(10):931-934.
Black SM, Field-Ridley A, Sharma S, Kumar S, Keller RL, Kameny R, Maltepe E, Datar SA, Fineman JR. PMID: 28723882; PMCID: PMC5628126.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Pulmonary veno-occlusive disease in a pediatric hematopoietic stem cell transplant patient: a cautionary tale. Leuk Lymphoma. 2018 06; 59(6):1494-1497.
Zinter MS, Melton A, Sabnis AJ, Dvorak CC, Elicker BM, Nawaytou HM, Kameny RJ, Fineman JR. PMID: 28958195; PMCID: PMC5897181.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Pushing the envelope: a treat and repair strategy for patients with advanced pulmonary hypertension associated with congenital heart disease. Pulm Circ. 2017 Jul-Sep; 7(3):747-751.
Kameny RJ, Colglazier E, Nawaytou H, Moore P, Reddy VM, Teitel D, Fineman JR. PMID: 28862067; PMCID: PMC5841911.
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PubMed Mentions:
5
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Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia. J Pediatr. 2017 09; 188:24-34.e1.
Krishnan U, Feinstein JA, Adatia I, Austin ED, Mullen MP, Hopper RK, Hanna B, Romer L, Keller RL, Fineman J, Steinhorn R, Kinsella JP, Ivy DD, Rosenzweig EB, Raj U, Humpl T, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet). PMID: 28645441.
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PubMed Mentions:
90 Fields:
Translation:
Humans
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Pulmonary vein stenosis of ex-premature infants with pulmonary hypertension and bronchopulmonary dysplasia, epidemiology, and survival from a multicenter cohort. Pediatr Pulmonol. 2017 08; 52(8):1063-1070.
Mahgoub L, Kaddoura T, Kameny AR, Lopez Ortego P, Vanderlaan RD, Kakadekar A, Dicke F, Rebeyka I, Calderone CA, Redington A, Del Cerro MJ, Fineman J, Adatia I. PMID: 28152279.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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The Prescient Prognosticator? Hepatoma-derived Growth Factor in Pulmonary Hypertension. Am J Respir Crit Care Med. 2016 11 15; 194(10):1186-1187.
Kameny RJ, Fineman JR. PMID: 27845583; PMCID: PMC5114444.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation. Am J Physiol Heart Circ Physiol. 2016 10 01; 311(4):H944-H957.
Boehme J, Sun X, Tormos KV, Gong W, Kellner M, Datar SA, Kameny RJ, Yuan JX, Raff GW, Fineman JR, Black SM, Maltepe E. PMID: 27591215; PMCID: PMC5114466.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Bosentan as Adjunctive Therapy for Persistent Pulmonary Hypertension of the Newborn: Results of the Randomized Multicenter Placebo-Controlled Exploratory Trial. J Pediatr. 2016 Oct; 177:90-96.e3.
Steinhorn RH, Fineman J, Kusic-Pajic A, Cornelisse P, Gehin M, Nowbakht P, Pierce CM, Beghetti M, FUTURE-4 study investigators. PMID: 27502103.
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PubMed Mentions:
35 Fields:
Translation:
HumansCTClinical Trials
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Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells. Am J Respir Cell Mol Biol. 2016 08; 55(2):275-87.
Sun X, Kellner M, Desai AA, Wang T, Lu Q, Kangath A, Qu N, Klinger C, Fratz S, Yuan JX, Jacobson JR, Garcia JG, Rafikov R, Fineman JR, Black SM. PMID: 26959555; PMCID: PMC4979361.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Pulmonary Hypertension. Pediatr Crit Care Med. 2016 08; 17(8 Suppl 1):S140-5.
Oishi P, Fineman JR. PMID: 27490592; PMCID: PMC4975433.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Disrupted NOS signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow. Am J Physiol Heart Circ Physiol. 2016 07 01; 311(1):H137-45.
Datar SA, Gong W, He Y, Johengen M, Kameny RJ, Raff GW, Maltepe E, Oishi PE, Fineman JR. PMID: 27199125; PMCID: PMC4967199.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung. PLoS One. 2016; 11(3):e0150480.
Rafikova O, Meadows ML, Kinchen JM, Mohney RP, Maltepe E, Desai AA, Yuan JX, Garcia JG, Fineman JR, Rafikov R, Black SM. PMID: 26937637; PMCID: PMC4777490.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Change in Pediatric Functional Classification During Treatment and Morbidity and Mortality in Children with Pulmonary Hypertension. Pediatr Cardiol. 2016 Apr; 37(4):756-64.
Balkin EM, Olson ED, Robertson L, Adatia I, Fineman JR, Keller RL. PMID: 26843461; PMCID: PMC4826405.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Overexpression of Nitric Oxide Synthase Restores Circulating Angiogenic Cell Function in Patients With Coronary Artery Disease: Implications for Autologous Cell Therapy for Myocardial Infarction. J Am Heart Assoc. 2016 Jan 06; 5(1).
Chen Q, Varga M, Wang X, Haddad DJ, An S, Medzikovic L, Derakhshandeh R, Kostyushev DS, Zhang Y, Clifford BT, Luu E, Danforth OM, Rafikov R, Gong W, Black SM, Suchkov SV, Fineman JR, Heiss C, Aschbacher K, Yeghiazarians Y, Springer ML. PMID: 26738788; PMCID: PMC4859354.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2016 Mar; 170:312-4.
Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. PMID: 26703869.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99.
Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL, American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitatio. PMID: 26534956.
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PubMed Mentions:
376 Fields:
Translation:
Humans
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Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Rep. 2015 Nov 03; 13(5):1016-32.
Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. PMID: 26565914; PMCID: PMC4644508.
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PubMed Mentions:
139 Fields:
Translation:
HumansAnimalsCells
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Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells. Redox Biol. 2015 Dec; 6:278-286.
Rafikov R, Sun X, Rafikova O, Louise Meadows M, Desai AA, Khalpey Z, Yuan JX, Fineman JR, Black SM. PMID: 26298201; PMCID: PMC4556771.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Short-Term Treprostinil Use in Infants with Congenital Diaphragmatic Hernia following Repair. J Pediatr. 2015 Sep; 167(3):762-4.
Olson E, Lusk LA, Fineman JR, Robertson L, Keller RL. PMID: 26143384; PMCID: PMC4554975.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Right ventricular nitric oxide signaling in an ovine model of congenital heart disease: a preserved fetal phenotype. Am J Physiol Heart Circ Physiol. 2015 Jul 01; 309(1):H157-65.
Kameny RJ, He Y, Morris C, Sun C, Johengen M, Gong W, Raff GW, Datar SA, Oishi PE, Fineman JR. PMID: 25934095; PMCID: PMC4491525.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Longitudinal development of obesity in the post-Fontan population. Eur J Clin Nutr. 2015 Oct; 69(10):1105-8.
Wellnitz K, Harris IS, Sapru A, Fineman JR, Radman M. PMID: 25920422.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress. J Cell Physiol. 2014 Nov; 229(11):1802-16.
Gross CM, Aggarwal S, Kumar S, Tian J, Kasa A, Bogatcheva N, Datar SA, Verin AD, Fineman JR, Black SM. PMID: 24677020; PMCID: PMC4117725.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
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Are preoperative B-type natriuretic peptide levels associated with outcome after pulmonary artery banding and the double switch operation in patients with congenitally corrected transposition of the great arteries: a pilot study. J Thorac Cardiovasc Surg. 2014 Nov; 148(5):2434-6.
Char DS, Shiboski SC, Hanley FL, Fineman JR. PMID: 25135237.
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Translation:
HumansCells
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Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2014 08; 124(8):3514-28.
Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. PMID: 24960162; PMCID: PMC4109523.
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PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase. Am J Respir Cell Mol Biol. 2014 Jun; 50(6):1084-95.
Sun X, Kumar S, Sharma S, Aggarwal S, Lu Q, Gross C, Rafikova O, Lee SG, Dasarathy S, Hou Y, Meadows ML, Han W, Su Y, Fineman JR, Black SM. PMID: 24392990; PMCID: PMC4068912.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Adaptive right ventricular performance in response to acutely increased afterload in a lamb model of congenital heart disease: evidence for enhanced Anrep effect. Am J Physiol Heart Circ Physiol. 2014 Apr 15; 306(8):H1222-30.
Johnson RC, Datar SA, Oishi PE, Bennett S, Maki J, Sun C, Johengen M, He Y, Raff GW, Redington AN, Fineman JR. PMID: 24561861; PMCID: PMC3989751.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Altered reactivity and nitric oxide signaling in the isolated thoracic duct from an ovine model of congenital heart disease with increased pulmonary blood flow. Am J Physiol Heart Circ Physiol. 2014 Apr 01; 306(7):H954-62.
Datar SA, Oishi PE, Gong W, Bennett SH, Sun CE, Johengen M, Maki J, Johnson RC, Raff GW, Fineman JR. PMID: 24531811; PMCID: PMC4116402.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding. J Biol Chem. 2014 Mar 14; 289(11):7948-61.
Aggarwal S, Gross CM, Rafikov R, Kumar S, Fineman JR, Ludewig B, Jonigk D, Black SM. PMID: 24469460; PMCID: PMC3953305.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167. Free Radic Biol Med. 2014 Feb; 67:255-64.
Rafikov R, Kumar S, Aggarwal S, Hou Y, Kangath A, Pardo D, Fineman JR, Black SM. PMID: 24211614; PMCID: PMC3945115.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Antenatal maternally-administered phosphodiesterase type 5 inhibitors normalize eNOS expression in the fetal lamb model of congenital diaphragmatic hernia. J Pediatr Surg. 2014 Jan; 49(1):39-45; discussion 45.
Shue EH, Schecter SC, Gong W, Etemadi M, Johengen M, Iqbal C, Derderian SC, Oishi P, Fineman JR, Miniati D. PMID: 24439578; PMCID: PMC3896891.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Preoperative B-type natriuretic peptide levels are associated with outcome after total cavopulmonary connection (Fontan). J Thorac Cardiovasc Surg. 2014 Jul; 148(1):212-9.
Radman M, Keller RL, Oishi P, Datar SA, Wellnitz K, Azakie A, Hanley F, Char D, Hsu JH, Amrinovin R, Adatia I, Fineman JR. PMID: 24079880; PMCID: PMC3968237.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Reactive oxygen species in pulmonary vascular remodeling. Compr Physiol. 2013 Jul; 3(3):1011-34.
Aggarwal S, Gross CM, Sharma S, Fineman JR, Black SM. PMID: 23897679; PMCID: PMC3907081.
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PubMed Mentions:
67 Fields:
Translation:
HumansAnimals
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Reply to the editor. J Thorac Cardiovasc Surg. 2013 May; 145(5):1416.
Amirnovin R, Oishi P, Fineman JR, Keller RL. PMID: 23597627.
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Translation:
Humans
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L-carnitine preserves endothelial function in a lamb model of increased pulmonary blood flow. Pediatr Res. 2013 Jul; 74(1):39-47.
Sharma S, Aramburo A, Rafikov R, Sun X, Kumar S, Oishi PE, Datar SA, Raff G, Xoinis K, Kalkan G, Fratz S, Fineman JR, Black SM. PMID: 23628882; PMCID: PMC3709010.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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The effect of preoperative nutritional status on postoperative outcomes in children undergoing surgery for congenital heart defects in San Francisco (UCSF) and Guatemala City (UNICAR). J Thorac Cardiovasc Surg. 2014 Jan; 147(1):442-50.
Radman M, Mack R, Barnoya J, Castañeda A, Rosales M, Azakie A, Mehta N, Keller R, Datar S, Oishi P, Fineman J. PMID: 23583172; PMCID: PMC3787941.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow. Antioxid Redox Signal. 2013 May 10; 18(14):1739-52.
Sun X, Sharma S, Fratz S, Kumar S, Rafikov R, Aggarwal S, Rafikova O, Lu Q, Burns T, Dasarathy S, Wright J, Schreiber C, Radman M, Fineman JR, Black SM. PMID: 23244702; PMCID: PMC3619212.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Differential responses of the right ventricle to abnormal loading conditions in vivo: possible pathophysiologic mechanisms. J Thorac Cardiovasc Surg. 2013 May; 145(5):1335-44.
Azakie A, Fineman J, He Y. PMID: 23434296.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Tezosentan increases nitric oxide signaling via enhanced hydrogen peroxide generation in lambs with surgically induced acute increases in pulmonary blood flow. J Cell Biochem. 2013 Feb; 114(2):435-447.
Kumar S, Oishi PE, Rafikov R, Aggarwal S, Hou Y, Datar SA, Sharma S, Azakie A, Fineman JR, Black SM. PMID: 22961736; PMCID: PMC3906673.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Chronic inhibition of PPAR-γ signaling induces endothelial dysfunction in the juvenile lamb. Pulm Pharmacol Ther. 2013 Apr; 26(2):271-80.
Sharma S, Barton J, Rafikov R, Aggarwal S, Kuo HC, Oishi PE, Datar SA, Fineman JR, Black SM. PMID: 23257346; PMCID: PMC3872991.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension. Am J Respir Crit Care Med. 2013 Mar 15; 187(6):572-5.
Abman SH, Kinsella JP, Rosenzweig EB, Krishnan U, Kulik T, Mullen M, Wessel DL, Steinhorn R, Adatia I, Hanna B, Feinstein J, Fineman J, Raj U, Humpl T, Pediatric Pulmonary Hypertension Network (PPHNet). PMID: 23220921.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flow. Pediatr Res. 2013 Jan; 73(1):54-61.
Oishi PE, Sharma S, Datar SA, Kumar S, Aggarwal S, Lu Q, Raff G, Azakie A, Hsu JH, Sajti E, Fratz S, Black SM, Fineman JR. PMID: 23128423; PMCID: PMC3977665.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Endostatin, an inhibitor of angiogenesis, decreases after bidirectional superior cavopulmonary anastamosis. Pediatr Cardiol. 2013 Feb; 34(2):291-5.
Field-Ridley A, Heljasvaara R, Pihlajaniemi T, Adatia I, Sun C, Keller RL, Gong WH, Datar S, Oishi P, Fineman JR. PMID: 22961274; PMCID: PMC3574568.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow. PLoS One. 2012; 7(9):e41555.
Sharma S, Sun X, Rafikov R, Kumar S, Hou Y, Oishi PE, Datar SA, Raff G, Fineman JR, Black SM. PMID: 22962578; PMCID: PMC3433474.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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B-type natriuretic peptide levels predict outcomes in infants undergoing cardiac surgery in a lesion-dependent fashion. J Thorac Cardiovasc Surg. 2013 May; 145(5):1279-87.
Amirnovin R, Keller RL, Herrera C, Hsu JH, Datar S, Karl TR, Adatia I, Oishi P, Fineman JR. PMID: 22914252; PMCID: PMC11257152.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Pulmonary interstitial glycogenosis: an unrecognized etiology of persistent pulmonary hypertension of the newborn in congenital heart disease? Pediatr Cardiol. 2013 Jun; 34(5):1254-7.
Radman MR, Goldhoff P, Jones KD, Azakie A, Datar S, Adatia I, Oishi PE, Fineman JR. PMID: 22614905; PMCID: PMC3651824.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. Free Radic Biol Med. 2012 Jul 15; 53(2):216-29.
Sharma S, Sun X, Kumar S, Rafikov R, Aramburo A, Kalkan G, Tian J, Rehmani I, Kallarackal S, Fineman JR, Black SM. PMID: 22583703; PMCID: PMC3527085.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Racial disparities in congenital heart disease: beyond red and blue. Pediatr Crit Care Med. 2012 Mar; 13(2):218-9.
Soskolne G, Collins JW, Fineman JR, Fuentes-Afflick E. PMID: 22391831.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Altered lymphatics in an ovine model of congenital heart disease with increased pulmonary blood flow. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15; 302(6):L530-40.
Datar SA, Johnson EG, Oishi PE, Johengen M, Tang E, Aramburo A, Barton J, Kuo HC, Bennett S, Xoinis K, Reel B, Kalkan G, Sajti E, Osorio O, Raff GW, Matthay MA, Fineman JR. PMID: 22207591; PMCID: PMC3311527.
View in:
PubMed Mentions:
12 Fields:
Translation:
Animals
-
Usefulness of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide as biomarkers for heart failure in young children with single ventricle congenital heart disease. Am J Cardiol. 2012 Mar 15; 109(6):866-72.
Lowenthal A, Camacho BV, Lowenthal S, Natal-Hernandez L, Liszewski W, Hills NK, Fineman JR, Bernstein HS. PMID: 22196786; PMCID: PMC3294194.
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PubMed Mentions:
15 Fields:
Translation:
Humans
-
Attenuated vasodilatation in lambs with endogenous and exogenous activation of cGMP signaling: role of protein kinase G nitration. J Cell Physiol. 2011 Dec; 226(12):3104-13.
Aggarwal S, Gross CM, Kumar S, Datar S, Oishi P, Kalkan G, Schreiber C, Fratz S, Fineman JR, Black SM. PMID: 21351102; PMCID: PMC3527072.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Advances in the management of pediatric pulmonary hypertension. Respir Care. 2011 Sep; 56(9):1314-39; discussion 1339-40.
Oishi P, Datar SA, Fineman JR. PMID: 21944683.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Pediatric pulmonary arterial hypertension: current and emerging therapeutic options. Expert Opin Pharmacother. 2011 Aug; 12(12):1845-64.
Oishi P, Datar SA, Fineman JR. PMID: 21609302.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Early determinants of pulmonary vascular remodeling in animal models of complex congenital heart disease. Circulation. 2011 Mar 01; 123(8):916-23.
Fratz S, Fineman JR, Görlach A, Sharma S, Oishi P, Schreiber C, Kietzmann T, Adatia I, Hess J, Black SM. PMID: 21357846; PMCID: PMC3873774.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease. Physiol Genomics. 2011 Jan 01; 43(2):87-98.
Tian J, Fratz S, Hou Y, Lu Q, Görlach A, Hess J, Schreiber C, Datar SA, Oishi P, Nechtman J, Podolsky R, She JX, Fineman JR, Black SM. PMID: 20978110; PMCID: PMC3026563.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Oxidative stress and the development of endothelial dysfunction in congenital heart disease with increased pulmonary blood flow: lessons from the neonatal lamb. Trends Cardiovasc Med. 2010 Oct; 20(7):238-46.
Aggarwal S, Gross C, Fineman JR, Black SM. PMID: 22293025; PMCID: PMC3527074.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Reciprocal regulation of Rac1 and PAK-1 by HIF-1alpha: a positive-feedback loop promoting pulmonary vascular remodeling. Antioxid Redox Signal. 2010 Aug 15; 13(4):399-412.
Diebold I, Petry A, Djordjevic T, Belaiba RS, Fineman J, Black S, Schreiber C, Fratz S, Hess J, Kietzmann T, Görlach A. PMID: 20001745.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Congenital diaphragmatic hernia: endothelin-1, pulmonary hypertension, and disease severity. Am J Respir Crit Care Med. 2010 Aug 15; 182(4):555-61.
Keller RL, Tacy TA, Hendricks-Munoz K, Xu J, Moon-Grady AJ, Neuhaus J, Moore P, Nobuhara KK, Hawgood S, Fineman JR. PMID: 20413632; PMCID: PMC2937245.
View in:
PubMed Mentions:
55 Fields:
Translation:
Humans
-
Nitric oxide alterations following acute ductal constriction in the fetal lamb: a role for superoxide. Am J Physiol Lung Cell Mol Physiol. 2010 Jun; 298(6):L880-7.
Hsu JH, Oishi P, Wiseman DA, Hou Y, Chikovani O, Datar S, Sajti E, Johengen MJ, Harmon C, Black SM, Fineman JR. PMID: 20363848; PMCID: PMC2886608.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow. Vascul Pharmacol. 2010 Jul-Aug; 53(1-2):38-52.
Sharma S, Kumar S, Wiseman DA, Kallarackal S, Ponnala S, Elgaish M, Tian J, Fineman JR, Black SM. PMID: 20362073; PMCID: PMC3815618.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Mass spectroscopy and molecular modeling predict endothelial nitric oxide synthase dimer collapse by hydrogen peroxide through zinc tetrathiolate metal-binding site disruption. DNA Cell Biol. 2010 Mar; 29(3):149-60.
Fonseca FV, Ravi K, Wiseman D, Tummala M, Harmon C, Ryzhov V, Fineman JR, Black SM. PMID: 20184449; PMCID: PMC2883531.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Early elevations in B-type natriuretic peptide levels are associated with poor clinical outcomes in pediatric acute lung injury. Pediatr Pulmonol. 2009 Nov; 44(11):1118-24.
Reel B, Oishi PE, Hsu JH, Gildengorin G, Matthay MA, Fineman JR, Flori H. PMID: 19830720; PMCID: PMC4427345.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
Usefulness of various plasma biomarkers for diagnosis of heart failure in children with single ventricle physiology. Am J Cardiol. 2009 Nov 01; 104(9):1280-4.
Shah A, Feraco AM, Harmon C, Tacy T, Fineman JR, Bernstein HS. PMID: 19840577; PMCID: PMC2791782.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension. Physiol Genomics. 2009 Dec 30; 40(1):48-60.
Tian J, Smith A, Nechtman J, Podolsky R, Aggarwal S, Snead C, Kumar S, Elgaish M, Oishi P, Göerlach A, Fratz S, Hess J, Catravas JD, Verin AD, Fineman JR, She JX, Black SM. PMID: 19825830; PMCID: PMC2807211.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
-
Alterations in lung arginine metabolism in lambs with pulmonary hypertension associated with increased pulmonary blood flow. Vascul Pharmacol. 2009 Nov-Dec; 51(5-6):359-64.
Sharma S, Kumar S, Sud N, Wiseman DA, Tian J, Rehmani I, Datar S, Oishi P, Fratz S, Venema RC, Fineman JR, Black SM. PMID: 19818875; PMCID: PMC2879580.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Peripheral arterial function in infants and young children with one-ventricle physiology and hypoxemia. Am J Cardiol. 2009 Mar 15; 103(6):862-6.
Natarajan S, Heiss C, Yeghiazarians Y, Fineman JR, Teitel DF, Tacy TA. PMID: 19268746.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: a role for oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L756-66.
Oishi PE, Wiseman DA, Sharma S, Kumar S, Hou Y, Datar SA, Azakie A, Johengen MJ, Harmon C, Fratz S, Fineman JR, Black SM. PMID: 18757524; PMCID: PMC2584884.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Perioperative B-type natriuretic peptide levels predict outcome after bidirectional cavopulmonary anastomosis and total cavopulmonary connection. J Thorac Cardiovasc Surg. 2008 Apr; 135(4):746-53.
Hsu JH, Oishi PE, Keller RL, Chikovani O, Karl TR, Azakie A, Adatia I, Fineman JR. PMID: 18374751.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
-
Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2008 Jan; 294(1):L46-56.
Sharma S, Sud N, Wiseman DA, Carter AL, Kumar S, Hou Y, Rau T, Wilham J, Harmon C, Oishi P, Fineman JR, Black SM. PMID: 18024721; PMCID: PMC3970936.
View in:
PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
-
Alterations in cGMP, soluble guanylate cyclase, phosphodiesterase 5, and B-type natriuretic peptide induced by chronic increased pulmonary blood flow in lambs. Pediatr Pulmonol. 2007 Nov; 42(11):1057-71.
Oishi P, Sharma S, Grobe A, Azakie A, Harmon C, Johengen MJ, Hsu JH, Fratz S, Black SM, Fineman JR. PMID: 17902145.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
B-type natriuretic peptide levels predict outcomes for children on extracorporeal life support after cardiac surgery. J Thorac Cardiovasc Surg. 2007 Nov; 134(5):1179-87.
Chikovani O, Hsu JH, Keller R, Karl TR, Azakie A, Adatia I, Oishi P, Fineman JR. PMID: 17976447.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
-
B-type natriuretic peptide levels predict outcome after neonatal cardiac surgery. J Thorac Cardiovasc Surg. 2007 Oct; 134(4):939-45.
Hsu JH, Keller RL, Chikovani O, Cheng H, Hollander SA, Karl TR, Azakie A, Adatia I, Oishi P, Fineman JR. PMID: 17903511.
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PubMed Mentions:
16 Fields:
Translation:
Humans
-
Nitric oxide and superoxide generation from endothelial NOS: modulation by HSP90. Am J Physiol Lung Cell Mol Physiol. 2007 Dec; 293(6):L1444-53.
Sud N, Sharma S, Wiseman DA, Harmon C, Kumar S, Venema RC, Fineman JR, Black SM. PMID: 17827253.
View in:
PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
Lung antioxidant enzymes are regulated by development and increased pulmonary blood flow. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L960-71.
Sharma S, Grobe AC, Wiseman DA, Kumar S, Englaish M, Najwer I, Benavidez E, Oishi P, Azakie A, Fineman JR, Black SM. PMID: 17631609.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
The role of nitric oxide synthase-derived reactive oxygen species in the altered relaxation of pulmonary arteries from lambs with increased pulmonary blood flow. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1491-7.
Lakshminrusimha S, Wiseman D, Black SM, Russell JA, Gugino SF, Oishi P, Steinhorn RH, Fineman JR. PMID: 17513498; PMCID: PMC2111047.
View in:
PubMed Mentions:
26 Fields:
Translation:
Animals
-
Pediatric pulmonary hypertension: Roles of endothelin-1 and nitric oxide. Clin Hemorheol Microcirc. 2007; 37(1-2):111-20.
Black SM, Kumar S, Wiseman D, Ravi K, Wedgwood S, Ryzhov V, Fineman JR. PMID: 17641401.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Fibroblast growth factor-2 expression is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr Res. 2007 Jan; 61(1):32-6.
Wedgwood S, Devol JM, Grobe A, Benavidez E, Azakie A, Fineman JR, Black SM. PMID: 17211137.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Abnormal vascular tone in infants and children with lung hypoplasia: Findings from cardiac catheterization and the response to chronic therapy. Pediatr Crit Care Med. 2006 Nov; 7(6):589-94.
Keller RL, Moore P, Teitel D, Hawgood S, McQuitty J, Fineman JR. PMID: 17006391.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Myocardial transcription factors are modulated during pathologic cardiac hypertrophy in vivo. J Thorac Cardiovasc Surg. 2006 Dec; 132(6):1262-71.
Azakie A, Fineman JR, He Y. PMID: 17140938.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Nesiritide acutely increases pulmonary and systemic levels of nitric oxide in patients with pulmonary hypertension. J Card Fail. 2006 Sep; 12(7):507-13.
Khush KK, De Marco T, Vakharia KT, Harmon C, Fineman JR, Chatterjee K, Michaels AD. PMID: 16952783.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Oxidative and nitrosative stress in pediatric pulmonary hypertension: roles of endothelin-1 and nitric oxide. Vascul Pharmacol. 2006 Nov; 45(5):308-16.
Black SM, Fineman JR. PMID: 17049313.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
BNP for pediatrics--not quite ready for primetime. Pediatr Crit Care Med. 2006 Jul; 7(4):388-9.
Oishi PE, Fineman JR. PMID: 16829829.
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PubMed Mentions: Fields:
Translation:
Humans
-
Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase. Am J Physiol Lung Cell Mol Physiol. 2006 Jun; 290(6):L1069-77.
Grobe AC, Wells SM, Benavidez E, Oishi P, Azakie A, Fineman JR, Black SM. PMID: 16684951.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansAnimals
-
Sp3 inhibits Sp1-mediated activation of the cardiac troponin T promoter and is downregulated during pathological cardiac hypertrophy in vivo. Am J Physiol Heart Circ Physiol. 2006 Aug; 291(2):H600-11.
Azakie A, Fineman JR, He Y. PMID: 16617124.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Alterations in plasma B-type natriuretic peptide levels after repair of congenital heart defects: a potential perioperative marker. J Thorac Cardiovasc Surg. 2006 Mar; 131(3):632-8.
Shih CY, Sapru A, Oishi P, Azakie A, Karl TR, Harmon C, Asija R, Adatia I, Fineman JR. PMID: 16515916.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Nitric oxide-endothelin-1 interactions after surgically induced acute increases in pulmonary blood flow in intact lambs. Am J Physiol Heart Circ Physiol. 2006 May; 290(5):H1922-32.
Oishi P, Azakie A, Harmon C, Fitzgerald RK, Grobe A, Xu J, Hendricks-Munoz K, Black SM, Fineman JR. PMID: 16339822.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Inhaled nitric oxide induced NOS inhibition and rebound pulmonary hypertension: a role for superoxide and peroxynitrite in the intact lamb. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L359-66.
Oishi P, Grobe A, Benavidez E, Ovadia B, Harmon C, Ross GA, Hendricks-Munoz K, Xu J, Black SM, Fineman JR. PMID: 16258003.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Divergent transcriptional enhancer factor-1 regulates the cardiac troponin T promoter. Am J Physiol Cell Physiol. 2005 Dec; 289(6):C1522-34.
Azakie A, Lamont L, Fineman JR, He Y. PMID: 16049055.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Endothelin-1 in congenital heart disease. Pediatr Res. 2005 May; 57(5 Pt 2):16R-20R.
Beghetti M, Black SM, Fineman JR. PMID: 15817494.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
Nitric oxide decreases surfactant protein gene expression in primary cultures of type II pneumocytes. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L950-7.
Lee JW, Gonzalez RF, Chapin CJ, Busch J, Fineman JR, Gutierrez JA. PMID: 15640287.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Tezosentan, a combined parenteral endothelin receptor antagonist, produces pulmonary vasodilation in lambs with acute and chronic pulmonary hypertension. Pediatr Crit Care Med. 2004 Nov; 5(6):571-7.
Fitzgerald RK, Oishi P, Ovadia B, Ross GA, Reinhartz O, Johengen MJ, Fineman JR. PMID: 15530195.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Endothelial alterations during inhaled NO in lambs with pulmonary hypertension: implications for rebound hypertension. Am J Physiol Lung Cell Mol Physiol. 2005 Jan; 288(1):L27-35.
Ross GA, Oishi P, Azakie A, Fratz S, Fitzgerald RK, Johengen MJ, Harmon C, Hendricks-Munoz K, Xu J, Black SM, Fineman JR. PMID: 15347565.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Chronic endothelin A receptor blockade in lambs with increased pulmonary blood flow and pressure. Am J Physiol Lung Cell Mol Physiol. 2004 Sep; 287(3):L592-7.
Fratz S, Meyrick B, Ovadia B, Johengen MJ, Reinhartz O, Azakie A, Ross G, Fitzgerald R, Oishi P, Hess J, Black SM, Fineman JR. PMID: 15155268.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Phosphodiesterase-3 inhibition prevents the increase in pulmonary vascular resistance following inhaled nitric oxide withdrawal in lambs. Pediatr Crit Care Med. 2004 May; 5(3):234-9.
Thelitz S, Oishi P, Sanchez LS, Bekker JM, Ovadia B, Johengen MJ, Black SM, Fineman JR. PMID: 15115560.
View in:
PubMed Mentions:
12 Fields:
Translation:
Animals
-
Impact of right ventricle to pulmonary artery conduit on outcome of the modified Norwood procedure. Ann Thorac Surg. 2004 May; 77(5):1727-33.
Azakie A, Martinez D, Sapru A, Fineman J, Teitel D, Karl TR. PMID: 15111174.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Inhaled nitric oxide decreases pulmonary soluble guanylate cyclase protein levels in 1-month-old lambs. J Thorac Cardiovasc Surg. 2004 May; 127(5):1285-92.
Thelitz S, Bekker JM, Ovadia B, Stuart RB, Johengen MJ, Black SM, Fineman JR. PMID: 15115984.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Treatment of rebound and chronic pulmonary hypertension with oral sildenafil in an infant with congenital diaphragmatic hernia. Pediatr Crit Care Med. 2004 Mar; 5(2):184-7.
Keller RL, Hamrick SE, Kitterman JA, Fineman JR, Hawgood S. PMID: 14987351.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Increased pulmonary blood flow does not alter surfactant protein gene expression in lambs within the first week of life. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1237-43.
Lee JW, Ovadia B, Azakie A, Salas S, Goerke J, Fineman JR, Gutierrez JA. PMID: 14751849.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Pharmacologic therapy for persistent pulmonary hypertension of the newborn: as "poly" as the disease itself. Pediatr Crit Care Med. 2004 Jan; 5(1):94-6.
Oishi P, Fineman JR. PMID: 14709984.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Emergence of smooth muscle cell endothelin B-mediated vasoconstriction in lambs with experimental congenital heart disease and increased pulmonary blood flow. Circulation. 2003 Sep 30; 108(13):1646-54.
Black SM, Mata-Greenwood E, Dettman RW, Ovadia B, Fitzgerald RK, Reinhartz O, Thelitz S, Steinhorn RH, Gerrets R, Hendricks-Munoz K, Ross GA, Bekker JM, Johengen MJ, Fineman JR. PMID: 12963646.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Inhaled nitric oxide increases surfactant protein gene expression in the intact lamb. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L628-33.
Stuart RB, Ovadia B, Suzara VV, Ross PA, Thelitz S, Fineman JR, Gutierrez JA. PMID: 12765879.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L222-31.
Mata-Greenwood E, Meyrick B, Soifer SJ, Fineman JR, Black SM. PMID: 12665467.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
-
Alterations in TGF-beta1 expression in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L209-21.
Mata-Greenwood E, Meyrick B, Steinhorn RH, Fineman JR, Black SM. PMID: 12665463.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Developmental differences in the shear stress-induced expression of endothelial NO synthase: changing role of AP-1. Am J Physiol Lung Cell Mol Physiol. 2003 Apr; 284(4):L650-62.
Wedgwood S, Mitchell CJ, Fineman JR, Black SM. PMID: 12533439.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
Alterations in ET-1, not nitric oxide, in 1-week-old lambs with increased pulmonary blood flow. Am J Physiol Heart Circ Physiol. 2003 Feb; 284(2):H480-90.
Ovadia B, Reinhartz O, Fitzgerald R, Bekker JM, Johengen MJ, Azakie A, Thelitz S, Black SM, Fineman JR. PMID: 12399254.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Pulmonary vascular K+ channel expression and vasoreactivity in a model of congenital heart disease. Am J Physiol Lung Cell Mol Physiol. 2002 Dec; 283(6):L1210-9.
Cornfield DN, Resnik ER, Herron JM, Reinhartz O, Fineman JR. PMID: 12388350.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow. Pediatr Res. 2002 Aug; 52(2):233-44.
Black SM, Bekker JM, McMullan DM, Parry AJ, Ovadia B, Reinhartz O, Lakshminrushimha S, Mata-Greenwood E, Steinhorn RH, Fineman JR. PMID: 12149501.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Nitric oxide-endothelin-1 interactions after acute ductal constriction in fetal lambs. Am J Physiol Heart Circ Physiol. 2002 Mar; 282(3):H862-71.
Ovadia B, Bekker JM, Fitzgerald RK, Kon A, Thelitz S, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR. PMID: 11834480.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Decreased surfactant proteins in lambs with pulmonary hypertension secondary to increased blood flow. Am J Physiol Lung Cell Mol Physiol. 2001 Nov; 281(5):L1264-70.
Gutierrez JA, Parry AJ, McMullan DM, Chapin CJ, Fineman JR. PMID: 11597919.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
sGC and PDE5 are elevated in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2001 Nov; 281(5):L1051-7.
Black SM, Sanchez LS, Mata-Greenwood E, Bekker JM, Steinhorn RH, Fineman JR. PMID: 11597895.
View in:
PubMed Mentions:
23 Fields:
Translation:
Animals
-
Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy. Circ Res. 2001 Aug 17; 89(4):357-64.
Wedgwood S, McMullan DM, Bekker JM, Fineman JR, Black SM. PMID: 11509453.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Inhaled nitric oxide-induced rebound pulmonary hypertension: role for endothelin-1. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H777-85.
McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR. PMID: 11158977.
View in:
PubMed Mentions:
23 Fields:
Translation:
Animals
-
Inhaled nitric oxide in neonates with persistent pulmonary hypertension. Lancet. 2001 Jan 13; 357(9250):118-20.
Tworetzky W, Bristow J, Moore P, Brook MM, Segal MR, Brasch RC, Hawgood S, Fineman JR. PMID: 11197402.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
-
Altered endothelium-dependent relaxations in lambs with high pulmonary blood flow and pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2001 Jan; 280(1):H311-7.
Steinhorn RH, Russell JA, Lakshminrusimha S, Gugino SF, Black SM, Fineman JR. PMID: 11123246.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
-
Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow. Circulation. 2000 Nov 07; 102(19 Suppl 3):III172-8.
McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Kon A, Heidersbach RS, Black SM, Fineman JR. PMID: 11082382.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Transthoracic intracardiac catheters in pediatric patients recovering from congenital heart defect surgery: associated complications and outcomes. Crit Care Med. 2000 Aug; 28(8):2997-3001.
Flori HR, Johnson LD, Hanley FL, Fineman JR. PMID: 10966285.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Management and outcomes of delayed sternal closure after cardiac surgery in neonates and infants. Crit Care Med. 2000 Apr; 28(4):1180-4.
McElhinney DB, Reddy VM, Parry AJ, Johnson L, Fineman JR, Hanley FL. PMID: 10809302.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Pulmonary blood flow alters nitric oxide production in patients undergoing device closure of atrial septal defects. J Am Coll Cardiol. 2000 Feb; 35(2):463-7.
Tworetzky W, Moore P, Bekker JM, Bristow J, Black SM, Fineman JR. PMID: 10676695.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Altered regulation of the ET-1 cascade in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr Res. 2000 Jan; 47(1):97-106.
Black SM, Bekker JM, Johengen MJ, Parry AJ, Soifer SJ, Fineman JR. PMID: 10625089.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Inhaled nitric oxide inhibits NOS activity in lambs: potential mechanism for rebound pulmonary hypertension. Am J Physiol. 1999 11; 277(5):H1849-56.
Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR. PMID: 10564139.
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PubMed Mentions:
34 Fields:
Translation:
Animals
-
The pathophysiology of pulmonary hypertension in congenital heart disease. Artif Organs. 1999 Nov; 23(11):970-4.
Steinhorn RH, Fineman JR. PMID: 10564299.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Alveolar capillary dysplasia: diagnostic potential for cardiac catheterization. J Perinatol. 1999 Sep; 19(6 Pt 1):441-6.
Hintz SR, Vincent JA, Pitlick PT, Fineman JR, Steinhorn RH, Kim GE, Benitz WE. PMID: 10685275.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Inhaled nitric oxide, oxygen, and alkalosis: dose-response interactions in a lamb model of pulmonary hypertension. Pediatr Pulmonol. 1999 Jul; 28(1):3-11.
Heidersbach RS, Johengen MJ, Bekker JM, Fineman JR. PMID: 10406044.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Altered endothelial function in lambs with pulmonary hypertension and acute lung injury. Pediatr Pulmonol. 1999 Mar; 27(3):147-56.
Fineman JR, Wong J, Mikhailov T, Vanderford PA, Jerome HE, Soifer SJ. PMID: 10213252.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Endothelin receptor blockade prevents the rise in pulmonary vascular resistance after cardiopulmonary bypass in lambs with increased pulmonary blood flow. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):314-23.
Petrossian E, Parry AJ, Reddy VM, Akkersdijk GP, McMullan DM, Thompson L, Hendricks-Munoz KD, Hallak H, Hanley FL, Fineman JR. PMID: 9918974.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Role of the endothelium in placental dysfunction after fetal cardiac bypass. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):343-51.
Reddy VM, McElhinney DB, Rajasinghe HA, Liddicoat JR, Hendricks-Munoz K, Fineman JR, Hanley FL. PMID: 9918976.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Endothelin-receptor blockade does not alter closure of the ductus arteriosus. Am J Physiol. 1998 11; 275(5):H1620-6.
Fineman JR, Takahashi Y, Roman C, Clyman RI. PMID: 9815069.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Increased endothelial NOS in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol. 1998 11; 275(5):H1643-51.
Black SM, Fineman JR, Steinhorn RH, Bristow J, Soifer SJ. PMID: 9815072.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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The effects of inhaled nitric oxide on postoperative pulmonary hypertension in infants and children undergoing surgical repair of congenital heart disease. Anesth Analg. 1998 Jul; 87(1):46-51.
Russell IA, Zwass MS, Fineman JR, Balea M, Rouine-Rapp K, Brook M, Hanley FL, Silverman NH, Cahalan MK. PMID: 9661544.
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PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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Increased pulmonary blood flow alters the molecular regulation of vascular reactivity in the lamb. Chest. 1998 Jul; 114(1 Suppl):39S.
Black S, Fineman J, Johengen M, Bristow J, Soifer S. PMID: 9676621.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Models of persistent pulmonary hypertension of the newborn (PPHN) and the role of cyclic guanosine monophosphate (GMP) in pulmonary vasorelaxation. Semin Perinatol. 1997 Oct; 21(5):393-408.
Steinhorn RH, Morin FC, Fineman JR. PMID: 9352612.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Inhaled nitric oxide enhances oxygenation but not survival in infants with alveolar capillary dysplasia. J Pediatr. 1997 Mar; 130(3):417-22.
Steinhorn RH, Cox PN, Fineman JR, Finer NN, Rosenberg EM, Silver MM, Tyebkhan J, Zwass MS, Morin FC. PMID: 9063417.
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PubMed Mentions:
12 Fields:
Translation:
Humans
-
Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. N Engl J Med. 1997 Feb 27; 336(9):605-10.
Roberts JD, Fineman JR, Morin FC, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM. PMID: 9032045.
View in:
PubMed Mentions:
161 Fields:
Translation:
HumansCTClinical Trials
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Post-cardiopulmonary bypass pulmonary hypertension in lambs with increased pulmonary blood flow. A role for endothelin 1. Circulation. 1997 Feb 18; 95(4):1054-61.
Reddy VM, Hendricks-Munoz KD, Rajasinghe HA, Petrossian E, Hanley FL, Fineman JR. PMID: 9054770.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Hemodynamic effects of epinephrine, bicarbonate and calcium in the early postnatal period in a lamb model of single-ventricle physiology created in utero. J Am Coll Cardiol. 1996 Dec; 28(7):1877-83.
Reddy VM, Liddicoat JR, McElhinney DB, Fineman JR, Klein JR, Chang R, Hanley FL. PMID: 8962579.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
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Fetal model of single ventricle physiology: hemodynamic effects of oxygen, nitric oxide, carbon dioxide, and hypoxia in the early postnatal period. J Thorac Cardiovasc Surg. 1996 Aug; 112(2):437-49.
Reddy VM, Liddicoat JR, Fineman JR, McElhinney DB, Klein JR, Hanley FL. PMID: 8751513.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
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Altered endothelium-dependent responses in lambs with pulmonary hypertension and increased pulmonary blood flow. Am J Physiol. 1996 Aug; 271(2 Pt 2):H562-70.
Reddy VM, Wong J, Liddicoat JR, Johengen M, Chang R, Fineman JR. PMID: 8770097.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Exogenous endothelin-1 causes renal vasodilation in the fetal lamb. J Urol. 1996 Aug; 156(2 Pt 2):847-53.
Bogaert GA, Kogan BA, Mevorach RA, Wong J, Gluckman GR, Fineman JR, Heymann MA. PMID: 8683799.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Endothelin receptor blockade does not alter the increase in pulmonary blood flow due to oxygen ventilation in fetal lambs. Pediatr Res. 1996 Jul; 40(1):152-7.
Winters JW, Wong J, Van Dyke D, Johengen M, Heymann MA, Fineman JR. PMID: 8798262.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Invited editorial on "Antenatal betamethasone therapy augments nitric oxide-mediated relaxation of preterm ovine pulmonary veins". J Appl Physiol (1985). 1996 Feb; 80(2):388-9.
Fineman JR, Taeusch HW. PMID: 8929573.
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PubMed Mentions: Fields:
Translation:
Animals
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Endothelin-1 vasoactive responses in lambs with pulmonary hypertension and increased pulmonary blood flow. Am J Physiol. 1995 Dec; 269(6 Pt 2):H1965-72.
Wong J, Reddy VM, Hendricks-Munoz K, Liddicoat JR, Gerrets R, Fineman JR. PMID: 8594905.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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In utero placement of aortopulmonary shunts. A model of postnatal pulmonary hypertension with increased pulmonary blood flow in lambs. Circulation. 1995 Aug 01; 92(3):606-13.
Reddy VM, Meyrick B, Wong J, Khoor A, Liddicoat JR, Hanley FL, Fineman JR. PMID: 7634475.
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PubMed Mentions:
53 Fields:
Translation:
Animals
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Inhaled nitric oxide therapy for persistent pulmonary hypertension of the newborn. Acta Paediatr Jpn. 1995 Aug; 37(4):425-30.
Fineman JR, Zwass MS. PMID: 7572140.
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PubMed Mentions: Fields:
Translation:
Humans
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Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension. J Cardiovasc Pharmacol. 1995 Feb; 25(2):207-15.
Wong J, Vanderford PA, Winters J, Soifer SJ, Fineman JR. PMID: 7752646.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Regulation of pulmonary vascular tone in the perinatal period. Annu Rev Physiol. 1995; 57:115-34.
Fineman JR, Soifer SJ, Heymann MA. PMID: 7778860.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
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Inhaled nitric oxide in congenital hypoplasia of the lungs due to diaphragmatic hernia or oligohydramnios. Pediatrics. 1994 Nov; 94(5):715-8.
Karamanoukian HL, Glick PL, Zayek M, Steinhorn RH, Zwass MS, Fineman JR, Morin FC. PMID: 7936901.
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PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
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Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to congenital heart defects. Circulation. 1994 Sep; 90(3):1287-93.
Brook MM, Fineman JR, Bolinger AM, Wong AF, Heymann MA, Soifer SJ. PMID: 8087937.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Developmental effects of endothelin-1 on the pulmonary circulation in sheep. Pediatr Res. 1994 Sep; 36(3):394-401.
Wong J, Vanderford PA, Fineman JR, Soifer SJ. PMID: 7808838.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Chronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs. J Clin Invest. 1994 Jun; 93(6):2675-83.
Fineman JR, Wong J, Morin FC, Wild LM, Soifer SJ. PMID: 8201005; PMCID: PMC294514.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
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The role of endothelin and endothelin receptor subtypes in regulation of fetal pulmonary vascular tone. Pediatr Res. 1994 Jun; 35(6):664-70.
Wong J, Fineman JR, Heymann MA. PMID: 7936815.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs. J Cardiovasc Pharmacol. 1994 May; 23(5):806-13.
Crowley MR, Fineman JR, Soifer SJ. PMID: 7521465.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Diethylamine/nitric oxide (NO) adduct, an NO donor, produces potent pulmonary and systemic vasodilation in intact newborn lambs. J Cardiovasc Pharmacol. 1994 Jan; 23(1):113-9.
Vanderford PA, Wong J, Chang R, Keefer LK, Soifer SJ, Fineman JR. PMID: 7511722.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb. Am J Physiol. 1993 Oct; 265(4 Pt 2):H1318-25.
Wong J, Vanderford PA, Fineman JR, Chang R, Soifer SJ. PMID: 8238420.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Hyperoxia and alkalosis produce pulmonary vasodilation independent of endothelium-derived nitric oxide in newborn lambs. Pediatr Res. 1993 Apr; 33(4 Pt 1):341-6.
Fineman JR, Wong J, Soifer SJ. PMID: 8479813.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am J Physiol. 1993 Jan; 264(1 Pt 2):H252-8.
Braner DA, Fineman JR, Chang R, Soifer SJ. PMID: 8381611.
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PubMed Mentions:
9 Fields:
Translation:
Animals
-
Endothelin-1 does not mediate acute hypoxic pulmonary vasoconstriction in the intact newborn lamb. J Cardiovasc Pharmacol. 1993; 22 Suppl 8:S262-6.
Wong J, Vanderford PA, Winters JW, Chang R, Soifer SJ, Fineman JR. PMID: 7509961.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
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EDRF inhibition attenuates the increase in pulmonary blood flow due to oxygen ventilation in fetal lambs. J Appl Physiol (1985). 1992 Nov; 73(5):2151-7.
Moore P, Velvis H, Fineman JR, Soifer SJ, Heymann MA. PMID: 1474097.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
K+ channel pulmonary vasodilation in fetal lambs: role of endothelium-derived nitric oxide. J Appl Physiol (1985). 1992 Jul; 73(1):188-94.
Chang JK, Moore P, Fineman JR, Soifer SJ, Heymann MA. PMID: 1506367.
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PubMed Mentions: Fields:
Translation:
Animals
-
EDRF inhibition augments pulmonary hypertension in intact newborn lambs. Am J Physiol. 1992 May; 262(5 Pt 2):H1365-71.
Fineman JR, Chang R, Soifer SJ. PMID: 1590440.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs. Am J Physiol. 1991 Nov; 261(5 Pt 2):H1563-9.
Fineman JR, Chang R, Soifer SJ. PMID: 1659228.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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In vivo attenuation of endothelium-dependent pulmonary vasodilation by methylene blue. J Appl Physiol (1985). 1991 Aug; 71(2):735-41.
Fineman JR, Crowley MR, Heymann MA, Soifer SJ. PMID: 1657862.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
N omega-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs. Am J Physiol. 1991 Apr; 260(4 Pt 2):H1299-306.
Fineman JR, Heymann MA, Soifer SJ. PMID: 1849373.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Effects of vasoactive drugs on thromboxane A2 mimetic-induced pulmonary hypertension in newborn lambs. Pediatr Res. 1991 Feb; 29(2):167-72.
Crowley MR, Fineman JR, Soifer SJ. PMID: 2014153.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
The role of pulmonary vascular endothelium in perinatal pulmonary circulatory regulation. Semin Perinatol. 1991 Feb; 15(1):58-62.
Fineman JR, Soifer SJ, Heymann MA. PMID: 2063230.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Selective pulmonary vasodilation with ATP-MgCl2 during pulmonary hypertension in lambs. J Appl Physiol (1985). 1990 Nov; 69(5):1836-42.
Fineman JR, Crowley MR, Soifer SJ. PMID: 2272976.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals