Jeff Fineman, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
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    OMX-CV, A Novel Oxygen Delivery Biotherapeutic for Treatment of Hemorrhagic Shock in the Battlefield
    Dept. of the Army - USAMRAA 12865254-DM190076Sep 30, 2020 - Sep 29, 2023
    Role: Co-I
    Role Description: We propose that OMX-CV represent a unique class of precision oxygen delivery biotherapeutics with the potential to dramatically decrease reliance on conventional blood products during the treatment of hemorrhagic shock in the battlefield setting.
    Metabolic Reprogramming and Pulmonary Vascular Disease in Congenital Heart Disease
    NIH/NHLBI (University of Arizona) 1P01HL146369-01A1Aug 10, 2020 - Jul 31, 2025
    Role: Co-investigator – Core C Director and Project 1 Leader
    Role Description: As part of this program project, Dr. Fineman will create animal models of Congenital Heart Disease, perform whole animal experiments to complement the cellular and molecular studies of the program project, and generate primary cell culture lines derived from the animal models.
    Large Mammal Neuroprotective Clinical Platform
    Bill and Melinda Gates Foundation OPP1196539Aug 1, 2018 - Jul 31, 2022
    Role: Co-Investigator
    Role Description: The major goals of this project are to test therapeutic entities to minimize neurological injury using a large animal model of birth asphyxia.
    TOMORROW: pediaTric use Of Macitentan tO delay disease pRogRessiOn in PAH Worldwide
    Actelion Pharmaceuticals Ltd AC-055-312Apr 5, 2018 - Apr 5, 2023
    Role: Site Lead
    Role Description: This is an industry-sponsored clinical trial to assess efficacy, safety and pharmacokinetics of macitentan versus standard of care in children with pulmonary arterial hypertension (PAH).
    PPHNet BiOspecimen Laboratory Depot (PPHNet-BOLD)
    Cardiovascular Medical Research and Education Fund (Vanderbilt University Medical Center) VUMC64032Oct 1, 2017 - Sep 30, 2021
    Role: Site Lead
    Role Description: The major goal of this project is to establish a biospecimen repository linked to the phenotyped PPHNet reigestiry. This will provide ar esource of DNA, RNA, plasma, serum, and circulating peripheral blood mononuclear cells for investigators studying pediatric PH.
    Development of an oxygen delivery biotherapeutic for the preservation of myocardial function during pediatric cardiopulmonary bypass
    NIH R44HD094414Aug 1, 2017 - Aug 31, 2021
    Role: Co-Principal Investigator
    Perinatal NO signaling in congenital heart disease
    NIH R01HL137282Apr 1, 2017 - Feb 28, 2021
    Role: Co-Principal Investigator
    Research Training in Pediatric Critical Care Medicine
    NIH T32HD049303Apr 1, 2005 - Apr 30, 2022
    Role: Principal Investigator
    Perinatal Pulmonary Hypertension: Developmental Mediators
    NIH R01HL061284Jul 1, 1999 - Mar 31, 2018
    Role: Principal Investigator
    NIH M01RR001271Dec 1, 1981 - Mar 31, 2007
    Role: Co-Investigator

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