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Michael Matthay, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address35 Medical Center Way
San Francisco CA 94143
Phone415-353-1206
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    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityA.B.1969English
    University of PennsylvaniaM.D.1973School of Medicine
    University of Colorado Medical CenterInternship and Residency1976Internal Medicine
    University of California, San FranciscoFellowship1978Pulmonary DIvision
    University of California, San FranciscoFellowship1979Cardiovascular Research Institute

    Collapse Overview 
    Collapse Overview
    Dr. Matthay's overall focus is on improving clinical care of patients with acute respiratory failure from the acute respiratory distress syndrome and from sepsis. His research and clinical trials groups are very well funded by grants from the National Institute of Health. He also spends considerable time mentoring physicians and young faculty in career development and academic medicine.

    Collapse Research 
    Collapse Research Activities and Funding
    1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)
    NIH UH3HL141722Sep 23, 2019 - Aug 31, 2024
    Role: Co-Principal Investigator
    1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)
    NIH UG3HL141722Sep 23, 2019 - Aug 31, 2020
    Role: Co-Principal Investigator
    Prevention and Early Treatment of Acute Lung Injury
    NIH U01HL123004Jun 17, 2014 - Apr 30, 2021
    Role: Principal Investigator
    Allogeneic Human Mesenchymal Stem Cells for the Treatment of Acute Lung Injury
    NIH U01HL108713Sep 1, 2011 - Jun 30, 2018
    Role: Principal Investigator
    Title: Long-Term Oxygen Treatment Trial (LOTT) - Data Coordinating Center
    NIH N01HR000000Jan 3, 2011 - Dec 31, 2015
    Role: Co-Principal Investigator
    Mucosal Immune Barrier in Infection and Immunity
    NIH P01AI053194Sep 1, 2009 - Sep 24, 2008
    Role: Co-Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-16-0-1Sep 30, 2005 - Jul 15, 2013
    Role: Principal Investigator
    ARDS - SAILS Protocol
    NIH N01HR56166-16-0-4Sep 30, 2005 - Jul 15, 2013
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH/NHLBI N01HR56166-14-0-1Sep 30, 2005 - Oct 31, 2012
    Role: Principal Investigator
    ARDS - SAILS Protocol
    NIH/NHLBI N01HR56166-14-0-4Sep 30, 2005 - Oct 31, 2012
    Role: Principal Investigator
    ARDS - ALTA Protocol
    NIH/NHLBI N01HR56166Sep 30, 2005 - Sep 29, 2012
    Role: Co-Principal Investigator
    ARDS - EDEN Protocol
    NIH N01HR56166-6-0-3Sep 30, 2005 - Sep 29, 2012
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-7-0-1Sep 30, 2005 - Sep 29, 2012
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-9-0-1Sep 30, 2005 - Nov 30, 2011
    Role: Principal Investigator
    Transfusion and Lung Injury
    NIH P50HL081027Sep 30, 2005 - Aug 31, 2011
    Role: Co-Investigator
    SCCOR in translational research in Acute Lung Injury
    NIH P50HL074005Sep 30, 2003 - Jun 30, 2010
    Role: Principal Investigator
    Resolution of Clinical Lung Injury
    NIH R37HL051856Apr 1, 1996 - Mar 31, 2018
    Role: Principal Investigator
    RESOLUTION OF CLINICAL LUNG INJURY
    NIH R01HL051856Apr 1, 1996 - Mar 31, 2006
    Role: Principal Investigator
    CCTG CLINICAL NETWORK FOR ARDS TREATMENT--CRITICAL CARE
    NIH/NHLBI N01HR046059Sep 30, 1994 - Sep 29, 2001
    Role: Principal Investigator
    Lung Fluid Balance and Mesenchymal Stem Cells
    NIH R01HL051854Apr 8, 1994 - Sep 29, 2008
    Role: Principal Investigator
    ALVEOLAR EPITHELIAL LIQUID AND PROTEIN CLEARANCE
    NIH R01HL040626Jun 1, 1988 - Nov 30, 1989
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    PATHOPHYSIOLOGY OF LUNG LIQUID &PROTEIN EXCHANGE
    NIH P01HL025816Jun 1, 1980 - May 31, 1994
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse In The News
    Collapse Featured Presentations
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Global absence and targeting of protective immune states in severe COVID-19. Nature. 2021 Jan 25. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Im KW, Serwas NK, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, UCSF COMET Consortium , Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33494096.
      View in: PubMed   Mentions: 1     Fields:    
    2. The ARREST Pneumonia (Arrest Respiratory Failure due to Pneumonia) Trial: Rationale and Design. Ann Am Thorac Soc. 2021 Jan 25. Levitt JE, Festic E, Desai M, Hedlin H, Mahaffey KW, Rogers AJ, Gajic O, Matthay MA. PMID: 33493423.
      View in: PubMed   Mentions:    Fields:    
    3. COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone. Res Sq. 2021 Jan 14. Sarma A, Christenson S, Mick E, Deiss T, DeVoe C, Pisco A, Ghale R, Jauregui A, Byrne A, Moazed F, Spottiswoode N, Sinha P, Zha B, Neff N, Tan M, Serpa PH, Ansel KM, Wilson J, Leligdowicz A, Seigel E, Sirota M, DeRisi J, Matthay M, Consortium C, Hendrickson C, Kangelaris K, Krummel M, Woodruff P, Erle D, Calfee C, Langelier C. PMID: 33469573.
      View in: PubMed   Mentions:
    4. Molecular Markers of Telomere Dysfunction and Senescence are Common Findings in the Usual Interstitial Pneumonia Pattern of Lung Fibrosis. Histopathology. 2021 Jan 11. Lee JS, La J, Aziz S, Dobrinskikh E, Brownell R, Jones KD, Achtar-Zadeh N, Green G, Elicker BM, Golden JA, Matthay MA, Kukreja J, Schwartz DA, Wolters PJ. PMID: 33432658.
      View in: PubMed   Mentions:    Fields:    
    5. The ABO histo-blood group, endothelial activation, and acute respiratory distress syndrome risk in critical illness. J Clin Invest. 2021 Jan 04; 131(1). Reilly JP, Meyer NJ, Shashaty MG, Anderson BJ, Ittner C, Dunn TG, Lim B, Forker C, Bonk MP, Kotloff E, Feng R, Cantu E, Mangalmurti NS, Calfee CS, Matthay MA, Mikacenic C, Walley KR, Russell J, Christiani DC, Wurfel MM, Lanken PN, Reilly MP, Christie JD. PMID: 32931480.
      View in: PubMed   Mentions:    Fields:    
    6. The Pulmonary Metatranscriptome Prior to Pediatric Hematopoietic Cell Transplantation Identifies Post-HCT Lung Injury. Blood. 2020 Dec 23. Zinter MS, Lindemans C, Versluys B, Mayday MY, Sunshine S, Reyes G, Sirota M, Sapru A, Matthay MA, Kharbanda S, Dvorak CC, Boelens JJJ, DeRisi JL. PMID: 33512420.
      View in: PubMed   Mentions:    Fields:    
    7. A Neutrophil Subset Defined by Intracellular Olfactomedin 4 is Associated with Mortality in Sepsis. Am J Physiol Lung Cell Mol Physiol. 2020 Dec 23. Kangelaris KN, Clemens R, Fang X, Jauregui A, Liu T, Vessel K, Deiss T, Sinha P, Leligdowicz A, Liu KD, Zhuo H, Alder MN, Wong HR, Calfee CS, Lowell CA, Matthay MA. PMID: 33355521.
      View in: PubMed   Mentions:    Fields:    
    8. A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19. N Engl J Med. 2020 Dec 22. Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Davey VJ, Goodman A, Higgs ES, Murray DD, Murray TA, Paredes R, Parmar MKB, Phillips AN, Reilly C, Sharma S, Dewar RL, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD. PMID: 33356051.
      View in: PubMed   Mentions: 5     Fields:    
    9. Corticosteroids, COVID-19 pneumonia, and acute respiratory distress syndrome. J Clin Invest. 2020 12 01; 130(12):6218-6221. Matthay MA, Wick KD. PMID: 32976118.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    10. Biological Mechanisms of COVID-19 Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020 12 01; 202(11):1489-1491. Matthay MA, Leligdowicz A, Liu KD. PMID: 32997945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    11. Dose-Dependent Pulmonary Toxicity of Aerosolized Vitamin E Acetate. Am J Respir Cell Mol Biol. 2020 12; 63(6):748-757. Matsumoto S, Fang X, Traber MG, Jones KD, Langelier C, Hayakawa Serpa P, Calfee CS, Matthay MA, Gotts JE. PMID: 32822237.
      View in: PubMed   Mentions:    Fields:    
    12. Alternative Tobacco Product Use in Critically Ill Patients. Int J Environ Res Public Health. 2020 Nov 24; 17(23). Liu T, Deiss TJ, Lippi MW, Jauregui A, Vessel K, Ke S, Belzer A, Zhuo H, Kangelaris KN, Gomez AD, Matthay MA, Liu KD, Calfee CS. PMID: 33255164.
      View in: PubMed   Mentions:    Fields:    
    13. Phenotypes and personalized medicine in the acute respiratory distress syndrome. Intensive Care Med. 2020 Dec; 46(12):2136-2152. Matthay MA, Arabi YM, Siegel ER, Ware LB, Bos LDJ, Sinha P, Beitler JR, Wick KD, Curley MAQ, Constantin JM, Levitt JE, Calfee CS. PMID: 33206201.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2020 11 09. Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM. PMID: 33165621.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    15. Designing an ARDS trial for 2020 and beyond: focus on enrichment strategies. Intensive Care Med. 2020 Dec; 46(12):2153-2156. Ware LB, Matthay MA, Mebazaa A. PMID: 33136196.
      View in: PubMed   Mentions: 1     Fields:    
    16. Global Absence and Targeting of Protective Immune States in Severe COVID-19. bioRxiv. 2020 Oct 29. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33140050.
      View in: PubMed   Mentions:
    17. Dexamethasone in hospitalised patients with COVID-19: addressing uncertainties. Lancet Respir Med. 2020 12; 8(12):1170-1172. PMID: 33129421.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    18. Global Absence and Targeting of Protective Immune States in Severe COVID-19. Res Sq. 2020 Oct 28. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33140041.
      View in: PubMed   Mentions:
    19. Using best subset regression to identify clinical characteristics and biomarkers associated with sepsis-associated acute kidney injury. Am J Physiol Renal Physiol. 2020 12 01; 319(6):F979-F987. Kwong YD, Mehta KM, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson C, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD. PMID: 33044866.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol. 2020 Nov; 22(11):1295-1306. Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. PMID: 33046884.
      View in: PubMed   Mentions:    Fields:    
    21. Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation. PLoS One. 2020; 15(10):e0240319. PMID: 33021986.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. The endogenous capacity to produce proinflammatory mediators by the ex vivo human perfused lung. Intensive Care Med Exp. 2020 Sep 21; 8(1):56. Leligdowicz A, Ross JT, Nesseler N, Matthay MA. PMID: 32955627.
      View in: PubMed   Mentions:
    23. Monitoring Research Blood Sampling in Critically Ill Patients: Avoiding Iatrogenic Anemia. Am J Respir Crit Care Med. 2020 09 15; 202(6):885-887. Baron RM, Christman JW, Liu KD, Matthay MA, Self WH, McVerry BJ, Hite RD, Paine R, Wurfel MM, Shapiro NI, Adams PW, Schmidt EP, Ringwood N. PMID: 32357306.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    24. Insufficient hyperfibrinolysis in COVID-19: a systematic review of thrombolysis based on meta-analysis and meta-regression. medRxiv. 2020 Sep 11. Ji HJ, Su Z, Zhao R, Komissarov AA, Yi G, Liu SL, Idell S, Matthay MA. PMID: 32935113.
      View in: PubMed   Mentions:
    25. NT-proBNP levels in the identification and classification of pulmonary transfusion reactions. Transfusion. 2020 Nov; 60(11):2548-2556. Roubinian NH, Chowdhury D, Hendrickson JE, Triulzi DJ, Gottschall JL, Looney MR, Matthay MA, Kor DJ, Brambilla D, Kleinman SH, Murphy EL. PMID: 32905629.
      View in: PubMed   Mentions:    Fields:    
    26. Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells. Am J Physiol Lung Cell Mol Physiol. 2020 12 01; 319(6):L908-L925. Abreu SC, Hampton TH, Hoffman E, Dearborn J, Ashare A, Singh Sidhu K, Matthews DE, McKenna DH, Amiel E, Barua J, Krasnodembskaya A, English K, Mahon B, Dos Santos C, Cruz FF, Chambers DC, Liu KD, Matthay MA, Cramer RA, Stanton BA, Rocco PRM, Wargo MJ, Weiss DJ, Rolandsson Enes S. PMID: 32901521.
      View in: PubMed   Mentions:    Fields:    
    27. Is a "Cytokine Storm" Relevant to COVID-19? JAMA Intern Med. 2020 09 01; 180(9):1152-1154. Sinha P, Matthay MA, Calfee CS. PMID: 32602883.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCellsPHPublic Health
    28. Need for Additional Trials of Vitamin C for Sepsis. JAMA. 2020 08 11; 324(6):607-608. Files DC, Liu KD, Matthay M. PMID: 32780134.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Association of patient weight status with plasma surfactant protein D, a biomarker of alveolar epithelial injury, in children with acute respiratory failure. Pediatr Pulmonol. 2020 10; 55(10):2730-2736. Ward SL, Dahmer MK, Weeks HM, Sapru A, Quasney MW, Curley MAQ, Liu KD, Matthay MA, Flori HR. PMID: 32725941.
      View in: PubMed   Mentions:    Fields:    
    30. Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep. Am J Respir Crit Care Med. 2020 08 01; 202(3):383-392. Millar JE, Bartnikowski N, Passmore MR, Obonyo NG, Malfertheiner MV, von Bahr V, Redd MA, See Hoe L, Ki KK, Pedersen S, Boyle AJ, Baillie JK, Shekar K, Palpant N, Suen JY, Matthay MA, McAuley DF, Fraser JF. PMID: 32293914.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    31. Higher plasma cystatin C is associated with mortality after acute respiratory distress syndrome: findings from a Fluid and Catheter Treatment Trial (FACTT) substudy. Crit Care. 2020 07 11; 24(1):416. Hendrickson CM, Kwong YD, Belzer AG, Shlipak MG, Matthay MA, Liu KD. PMID: 32653023.
      View in: PubMed   Mentions:    Fields:    
    32. Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2020 07; 63(1):15-24. Mahida RY, Matsumoto S, Matthay MA. PMID: 32109144.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    33. The ex vivo perfused human lung is resistant to injury by high-dose S. pneumoniae bacteremia. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L218-L227. Ross JT, Nesseler N, Leligdowicz A, Zemans RL, Mahida RY, Minus E, Langelier C, Gotts JE, Matthay MA. PMID: 32519893.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    34. Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time. Crit Care Med. 2020 Jun; 48(6):830-837. Schwede M, Lee RY, Zhuo H, Kangelaris KN, Jauregui A, Vessel K, Belzer A, Deiss T, Matthay MA, Liu KD, Calfee CS. PMID: 32317598.
      View in: PubMed   Mentions:    Fields:    
    35. Impact of Bilateral Infiltrates on Inflammatory Biomarker Levels and Clinical Outcomes of Children With Oxygenation Defect. Crit Care Med. 2020 Jun; 48(6):e498-e504. Kohne JG, Dahmer MK, Weeks HM, Kaciroti N, Quasney MW, Sapru A, Curley MAQ, Matthay M, Flori H. PMID: 32317601.
      View in: PubMed   Mentions:    Fields:    
    36. Plasmin improves blood-gas barrier function in oedematous lungs by cleaving epithelial sodium channels. Br J Pharmacol. 2020 Jul; 177(13):3091-3106. Zhao R, Ali G, Nie HG, Chang Y, Bhattarai D, Su X, Zhao X, Matthay MA, Ji HL. PMID: 32133621.
      View in: PubMed   Mentions: 5     Fields:    
    37. Patterns and Trends in Advance Care Planning Among Older Adults Who Received Intensive Care at the End of Life. JAMA Intern Med. 2020 05 01; 180(5):786-789. Block BL, Jeon SY, Sudore RL, Matthay MA, Boscardin WJ, Smith AK. PMID: 32119031.
      View in: PubMed   Mentions: 1     Fields:    
    38. The potential of lipid mediator networks as ocular surface therapeutics and biomarkers. Ocul Surf. 2020 Apr 29. Flitter BA, Fang X, Matthay MA, Gronert K. PMID: 32360792.
      View in: PubMed   Mentions:    Fields:    
    39. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun. 2020 04 21; 11(1):1920. Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. PMID: 32317643.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    40. Surfactant Protein D Is Associated With Severe Pediatric ARDS, Prolonged Ventilation, and Death in Children With Acute Respiratory Failure. Chest. 2020 Sep; 158(3):1027-1035. Dahmer MK, Flori H, Sapru A, Kohne J, Weeks HM, Curley MAQ, Matthay MA, Quasney MW. PMID: 32275979.
      View in: PubMed   Mentions: 1     Fields:    
    41. Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis. Respir Res. 2020 Apr 07; 21(1):81. Carla A, Pereira B, Boukail H, Audard J, Pinol-Domenech N, De Carvalho M, Blondonnet R, Zhai R, Morand D, Lambert C, Sapin V, Ware LB, Calfee CS, Bastarache JA, Laffey JG, Juffermans NP, Bos LD, Artigas A, Rocco PRM, Matthay MA, McAuley DF, Constantin JM, Jabaudon M. PMID: 32264897.
      View in: PubMed   Mentions: 1     Fields:    
    42. Gender Differences in Authorship of Critical Care Literature. Am J Respir Crit Care Med. 2020 04 01; 201(7):840-847. Vranas KC, Ouyang D, Lin AL, Slatore CG, Sullivan DR, Kerlin MP, Liu KD, Baron RM, Calfee CS, Ware LB, Halpern SD, Matthay MA, Herridge MS, Mehta S, Rogers AJ. PMID: 31968182.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility. Physiol Rev. 2020 07 01; 100(3):1065-1075. Ji HL, Zhao R, Matalon S, Matthay MA. PMID: 32216698.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCellsPHPublic Health
    44. Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis. Intensive Care Med. 2020 06; 46(6):1222-1231. Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS. PMID: 32206845.
      View in: PubMed   Mentions: 4     Fields:    
    45. Treatment for severe acute respiratory distress syndrome from COVID-19. Lancet Respir Med. 2020 05; 8(5):433-434. Matthay MA, Aldrich JM, Gotts JE. PMID: 32203709.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCellsPHPublic Health
    46. Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report. Am J Respir Crit Care Med. 2020 Mar 09. Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LA. PMID: 32150460.
      View in: PubMed   Mentions:    Fields:    
    47. Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study. J Thorac Cardiovasc Surg. 2020 Nov; 160(5):1385-1395.e6. Hamilton BCS, Dincheva GR, Matthay MA, Hays S, Singer JP, Brzezinski M, Kukreja J. PMID: 32252988.
      View in: PubMed   Mentions:    Fields:    
    48. Potential Value of Biomarker Signatures in Sepsis and Acute Respiratory Distress Syndrome in Children and Adults. Crit Care Med. 2020 03; 48(3):428-430. Hendrickson CM, Matthay MA. PMID: 32058380.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop. Intensive Care Med. 2020 05; 46(5):930-942. Harhay MO, Casey JD, Clement M, Collins SP, Gayat É, Gong MN, Jaber S, Laterre PF, Marshall JC, Matthay MA, Monroe RE, Rice TW, Rubin E, Self WH, Mebazaa A. PMID: 32072303.
      View in: PubMed   Mentions: 4     Fields:    
    50. Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. Crit Care Med. 2020 02; 48(2):200-209. Prasad PA, Fang MC, Abe-Jones Y, Calfee CS, Matthay MA, Kangelaris KN. PMID: 31939788.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1). Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475.
      View in: PubMed   Mentions: 5     Fields:    
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    133. Epithelial Sodium Channel-a Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction. Front Immunol. 2017; 8:842. Czikora I, Alli AA, Sridhar S, Matthay MA, Pillich H, Hudel M, Berisha B, Gorshkov B, Romero MJ, Gonzales J, Wu G, Huo Y, Su Y, Verin AD, Fulton D, Chakraborty T, Eaton DC, Lucas R. PMID: 28785264.
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    134. Endothelial Damage During Septic Shock: Significance and Implications for Future Therapies. Chest. 2017 07; 152(1):1-3. Crouser ED, Matthay MA. PMID: 28693760.
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    137. Lung Injury Etiology and Other Factors Influencing the Relationship Between Dead-Space Fraction and Mortality in ARDS. Respir Care. 2017 Oct; 62(10):1241-1248. Kallet RH, Zhuo H, Ho K, Lipnick MS, Gomez A, Matthay MA. PMID: 28611227.
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    145. Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome. Crit Care Med. 2017 May; 45(5):798-805. Festic E, Carr GE, Cartin-Ceba R, Hinds RF, Banner-Goodspeed V, Bansal V, Asuni AT, Talmor D, Rajagopalan G, Frank RD, Gajic O, Matthay MA, Levitt JE. PMID: 28240689.
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    146. Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2017 May; 45(5):858-866. Zinter MS, Orwoll BE, Spicer AC, Alkhouli MF, Calfee CS, Matthay MA, Sapru A. PMID: 28248715.
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    147. Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection. PLoS One. 2017; 12(4):e0175130. Leligdowicz A, Conroy AL, Hawkes M, Zhong K, Lebovic G, Matthay MA, Kain KC. PMID: 28419100.
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    148. Signals of vagal circuits engaging with AKT1 in a7 nAChR+CD11b+ cells lessen E. coli and LPS-induced acute inflammatory injury. Cell Discov. 2017; 3:17009. Zhao C, Yang X, Su EM, Huang Y, Li L, Matthay MA, Su X. PMID: 28529765.
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    155. Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death. Crit Care. 2016 11 17; 20(1):372. Bhatraju PK, Mukherjee P, Robinson-Cohen C, O'Keefe GE, Frank AJ, Christie JD, Meyer NJ, Liu KD, Matthay MA, Calfee CS, Christiani DC, Himmelfarb J, Wurfel MM. PMID: 27852290.
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    156. Clinical, Radiographic, Physiologic, and Biologic Measurements to Facilitate Personalized Medicine for ARDS. Chest. 2016 11; 150(5):989-990. Matthay MA, Beitler JR. PMID: 27832890.
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    157. Overnight Extubation in Patients With Mechanical Ventilation: Is It Harmful? JAMA Intern Med. 2016 11 01; 176(11):1660-1661. Moore PK, Matthay MA. PMID: 27599363.
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    158. What drives neutrophils to the alveoli in ARDS? Thorax. 2017 01; 72(1):1-3. Zemans RL, Matthay MA. PMID: 27974631.
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    159. Cathepsin L Helps to Defend Mice from Infection with Influenza A. PLoS One. 2016; 11(10):e0164501. Xu X, Greenland JR, Gotts JE, Matthay MA, Caughey GH. PMID: 27716790.
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    173. Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2016 May 15; 193(10):1143-50. Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. PMID: 26681363.
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    178. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):3621-6. Chan MC, Kuok DI, Leung CY, Hui KP, Valkenburg SA, Lau EH, Nicholls JM, Fang X, Guan Y, Lee JW, Chan RW, Webster RG, Matthay MA, Peiris JS. PMID: 26976597.
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    180. Acute Hypoxemic Respiratory Failure after Large-Volume Thoracentesis. Mechanisms of Pleural Fluid Formation and Reexpansion Pulmonary Edema. Ann Am Thorac Soc. 2016 Mar; 13(3):438-43. Walter JM, Matthay MA, Gillespie CT, Corbridge T. PMID: 26963356.
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    450. Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts. Am J Respir Cell Mol Biol. 2007 Apr; 36(4):480-90. Ning W, Dong Y, Sun J, Li C, Matthay MA, Feghali-Bostwick CA, Choi AM. PMID: 17099140.
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