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Michael Matthay, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address505 Parnassus Avenue
San Francisco CA 94117
Phone415-353-1206
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    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityA.B.1969English
    University of PennsylvaniaM.D.1973School of Medicine
    University of Colorado Medical CenterInternship and Residency1976Internal Medicine
    University of California, San FranciscoFellowship1978Pulmonary DIvision
    University of California, San FranciscoFellowship1979Cardiovascular Research Institute

    Collapse Overview 
    Collapse Overview
    Dr. Matthay's overall focus is on improving clinical care of patients with acute respiratory failure from the acute respiratory distress syndrome and from sepsis. His research and clinical trials groups are very well funded by grants from the National Institute of Health. He also spends considerable time mentoring physicians and young faculty in career development and academic medicine.

    Collapse Research 
    Collapse Research Activities and Funding
    1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)
    NIH/NHLBI UG3HL141722Sep 23, 2019 - Aug 31, 2024
    Role: Co-Principal Investigator
    Prevention and Early Treatment of Acute Lung Injury
    NIH/NHLBI U01HL123004Jun 17, 2014 - Apr 30, 2021
    Role: Principal Investigator
    Allogeneic Human Mesenchymal Stem Cells for the Treatment of Acute Lung Injury
    NIH/NHLBI U01HL108713Sep 1, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Mucosal Immune Barrier in Infection and Immunity
    NIH/NIAID P01AI053194Sep 1, 2009 - Sep 24, 2008
    Role: Co-Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-16-0-1Sep 30, 2005 - Jul 15, 2013
    Role: Principal Investigator
    ARDS - SAILS Protocol
    NIH N01HR56166-16-0-4Sep 30, 2005 - Jul 15, 2013
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH/NHLBI N01HR56166-14-0-1Sep 30, 2005 - Oct 31, 2012
    Role: Principal Investigator
    ARDS - SAILS Protocol
    NIH/NHLBI N01HR56166-14-0-4Sep 30, 2005 - Oct 31, 2012
    Role: Principal Investigator
    ARDS - ALTA Protocol
    NIH/NHLBI N01HR56166Sep 30, 2005 - Sep 29, 2012
    Role: Co-Principal Investigator
    ARDS - EDEN Protocol
    NIH/NHLBI N01HR56166-6-0-3Sep 30, 2005 - Sep 29, 2012
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH/NHLBI N01HR56166-7-0-1Sep 30, 2005 - Sep 29, 2012
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH/NHLBI N01HR56166-9-0-1Sep 30, 2005 - Nov 30, 2011
    Role: Principal Investigator
    Transfusion and Lung Injury
    NIH/NHLBI P50HL081027Sep 30, 2005 - Aug 31, 2011
    Role: Co-Investigator
    SCCOR in translational research in Acute Lung Injury
    NIH/NHLBI P50HL074005Sep 30, 2003 - Jun 30, 2010
    Role: Principal Investigator
    Resolution of Clinical Lung Injury
    NIH/NHLBI R37HL051856Apr 1, 1996 - Mar 31, 2016
    Role: Principal Investigator
    RESOLUTION OF CLINICAL LUNG INJURY
    NIH/NHLBI R01HL051856Apr 1, 1996 - Mar 31, 2006
    Role: Principal Investigator
    CCTG CLINICAL NETWORK FOR ARDS TREATMENT--CRITICAL CARE
    NIH/NHLBI N01HR046059Sep 30, 1994 - Sep 29, 2001
    Role: Principal Investigator
    Lung Fluid Balance and Mesenchymal Stem Cells
    NIH/NHLBI R01HL051854Apr 8, 1994 - Sep 29, 2008
    Role: Principal Investigator
    ALVEOLAR EPITHELIAL LIQUID AND PROTEIN CLEARANCE
    NIH/NHLBI R01HL040626Jun 1, 1988 - Nov 30, 1989
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    PATHOPHYSIOLOGY OF LUNG LIQUID &PROTEIN EXCHANGE
    NIH P01HL025816Jun 1, 1980 - May 31, 1994
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse In The News
    Collapse Featured Presentations
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. NT-proBNP levels in the identification and classification of pulmonary transfusion reactions. Transfusion. 2020 Sep 09. Roubinian NH, Chowdhury D, Hendrickson JE, Triulzi DJ, Gottschall JL, Looney MR, Matthay MA, Kor DJ, Brambilla D, Kleinman SH, Murphy EL. PMID: 32905629.
      View in: PubMed   Mentions:    Fields:    
    2. Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells. Am J Physiol Lung Cell Mol Physiol. 2020 Sep 09. Abreu SC, Hampton TH, Hoffman E, Dearborn J, Ashare A, Singh Sidhu K, Matthews DE, McKenna DH, Amiel E, Barua J, Krasnodembskaya A, English K, Mahon BP, Santos CD, Cruz FF, Chambers DC, Liu KD, Matthay MA, Cramer RA, Stanton BA, Rocco PRM, Wargo MJ, Weiss DJ, Rolandsson Enes S. PMID: 32901521.
      View in: PubMed   Mentions:    Fields:    
    3. Dose-Dependent Pulmonary Toxicity of Aerosolized Vitamin E Acetate. Am J Respir Cell Mol Biol. 2020 Aug 21. Matsumoto S, Fang X, Traber MG, Jones KD, Langelier C, Hayakawa Serpa P, Calfee CS, Matthay MA, Gotts JE. PMID: 32822237.
      View in: PubMed   Mentions:    Fields:    
    4. Need for Additional Trials of Vitamin C for Sepsis. JAMA. 2020 08 11; 324(6):607-608. Files DC, Liu KD, Matthay M. PMID: 32780134.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep. Am J Respir Crit Care Med. 2020 Aug 01; 202(3):383-392. Millar JE, Bartnikowski N, Passmore MR, Obonyo NG, Malfertheiner MV, von Bahr V, Redd MA, See Hoe L, Ki KK, Pedersen S, Boyle AJ, Baillie JK, Shekar K, Palpant N, Suen JY, Matthay MA, McAuley DF, Fraser JF. PMID: 32293914.
      View in: PubMed   Mentions: 1     Fields:    
    6. Association of patient weight status with plasma surfactant protein D, a biomarker of alveolar epithelial injury, in children with acute respiratory failure. Pediatr Pulmonol. 2020 Jul 29. Ward SL, Dahmer MK, Weeks HM, Sapru A, Quasney MW, Curley MAQ, Liu KD, Matthay MA, Flori HR. PMID: 32725941.
      View in: PubMed   Mentions:    Fields:    
    7. Higher plasma cystatin C is associated with mortality after acute respiratory distress syndrome: findings from a Fluid and Catheter Treatment Trial (FACTT) substudy. Crit Care. 2020 07 11; 24(1):416. Hendrickson CM, Kwong YD, Belzer AG, Shlipak MG, Matthay MA, Liu KD. PMID: 32653023.
      View in: PubMed   Mentions:    Fields:    
    8. Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2020 Jul; 63(1):15-24. Mahida RY, Matsumoto S, Matthay MA. PMID: 32109144.
      View in: PubMed   Mentions:    Fields:    
    9. Is a "Cytokine Storm" Relevant to COVID-19? JAMA Intern Med. 2020 Jun 30. Sinha P, Matthay MA, Calfee CS. PMID: 32602883.
      View in: PubMed   Mentions: 13     Fields:    
    10. The ex vivo perfused human lung is resistant to injury by high-dose S. pneumoniae bacteremia. Am J Physiol Lung Cell Mol Physiol. 2020 Aug 01; 319(2):L218-L227. Ross JT, Nesseler N, Leligdowicz A, Zemans RL, Mahida RY, Minus E, Langelier C, Gotts JE, Matthay MA. PMID: 32519893.
      View in: PubMed   Mentions:    Fields:    
    11. Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time. Crit Care Med. 2020 Jun; 48(6):830-837. Schwede M, Lee RY, Zhuo H, Kangelaris KN, Jauregui A, Vessel K, Belzer A, Deiss T, Matthay MA, Liu KD, Calfee CS. PMID: 32317598.
      View in: PubMed   Mentions:    Fields:    
    12. Impact of Bilateral Infiltrates on Inflammatory Biomarker Levels and Clinical Outcomes of Children With Oxygenation Defect. Crit Care Med. 2020 Jun; 48(6):e498-e504. Kohne JG, Dahmer MK, Weeks HM, Kaciroti N, Quasney MW, Sapru A, Curley MAQ, Matthay M, Flori H. PMID: 32317601.
      View in: PubMed   Mentions:    Fields:    
    13. Plasmin improves blood-gas barrier function in oedematous lungs by cleaving epithelial sodium channels. Br J Pharmacol. 2020 Jul; 177(13):3091-3106. Zhao R, Ali G, Nie HG, Chang Y, Bhattarai D, Su X, Zhao X, Matthay MA, Ji HL. PMID: 32133621.
      View in: PubMed   Mentions: 3     Fields:    
    14. Monitoring Research Blood Sampling in Critically Ill Patients: Avoiding Iatrogenic Anemia. Am J Respir Crit Care Med. 2020 May 01. Baron RM, Christman JW, Liu KD, Matthay MA, Self WH, McVerry BJ, Hite RD, Paine R, Wurfel MM, Shapiro NI, Adams PW, Schmidt EP, Ringwood N. PMID: 32357306.
      View in: PubMed   Mentions:    Fields:    
    15. The potential of lipid mediator networks as ocular surface therapeutics and biomarkers. Ocul Surf. 2020 Apr 29. Flitter BA, Fang X, Matthay MA, Gronert K. PMID: 32360792.
      View in: PubMed   Mentions:    Fields:    
    16. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun. 2020 04 21; 11(1):1920. Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. PMID: 32317643.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Surfactant Protein D Is Associated With Severe Pediatric Acute Respiratory Distress Syndrome, Prolonged Ventilation, and Death in Children With Acute Respiratory Failure. Chest. 2020 Apr 08. Dahmer MK, Flori H, Sapru A, Kohne J, Weeks HM, Curley MAQ, Matthay MA, Quasney MW. PMID: 32275979.
      View in: PubMed   Mentions:    Fields:    
    18. Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis. Respir Res. 2020 Apr 07; 21(1):81. Carla A, Pereira B, Boukail H, Audard J, Pinol-Domenech N, De Carvalho M, Blondonnet R, Zhai R, Morand D, Lambert C, Sapin V, Ware LB, Calfee CS, Bastarache JA, Laffey JG, Juffermans NP, Bos LD, Artigas A, Rocco PRM, Matthay MA, McAuley DF, Constantin JM, Jabaudon M. PMID: 32264897.
      View in: PubMed   Mentions:    Fields:    
    19. Gender Differences in Authorship of Critical Care Literature. Am J Respir Crit Care Med. 2020 04 01; 201(7):840-847. Vranas KC, Ouyang D, Lin AL, Slatore CG, Sullivan DR, Kerlin MP, Liu KD, Baron RM, Calfee CS, Ware LB, Halpern SD, Matthay MA, Herridge MS, Mehta S, Rogers AJ. PMID: 31968182.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility. Physiol Rev. 2020 07 01; 100(3):1065-1075. Ji HL, Zhao R, Matalon S, Matthay MA. PMID: 32216698.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCellsPHPublic Health
    21. Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis. Intensive Care Med. 2020 Jun; 46(6):1222-1231. Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS. PMID: 32206845.
      View in: PubMed   Mentions: 1     Fields:    
    22. Treatment for severe acute respiratory distress syndrome from COVID-19. Lancet Respir Med. 2020 05; 8(5):433-434. Matthay MA, Aldrich JM, Gotts JE. PMID: 32203709.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCellsPHPublic Health
    23. Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report. Am J Respir Crit Care Med. 2020 Mar 09. Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LA. PMID: 32150460.
      View in: PubMed   Mentions:    Fields:    
    24. Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study. J Thorac Cardiovasc Surg. 2020 Mar 04. Hamilton BCS, Dincheva GR, Matthay MA, Hays S, Singer JP, Brzezinski M, Kukreja J. PMID: 32252988.
      View in: PubMed   Mentions:    Fields:    
    25. Patterns and Trends in Advance Care Planning Among Older Adults Who Received Intensive Care at the End of Life. JAMA Intern Med. 2020 Mar 02. Block BL, Jeon SY, Sudore RL, Matthay MA, Boscardin WJ, Smith AK. PMID: 32119031.
      View in: PubMed   Mentions: 3     Fields:    
    26. Potential Value of Biomarker Signatures in Sepsis and Acute Respiratory Distress Syndrome in Children and Adults. Crit Care Med. 2020 Mar; 48(3):428-430. Hendrickson CM, Matthay MA. PMID: 32058380.
      View in: PubMed   Mentions:    Fields:    
    27. Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop. Intensive Care Med. 2020 May; 46(5):930-942. Harhay MO, Casey JD, Clement M, Collins SP, Gayat É, Gong MN, Jaber S, Laterre PF, Marshall JC, Matthay MA, Monroe RE, Rice TW, Rubin E, Self WH, Mebazaa A. PMID: 32072303.
      View in: PubMed   Mentions: 3     Fields:    
    28. Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. Crit Care Med. 2020 02; 48(2):200-209. Prasad PA, Fang MC, Abe-Jones Y, Calfee CS, Matthay MA, Kangelaris KN. PMID: 31939788.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1). Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475.
      View in: PubMed   Mentions: 2     Fields:    
    30. Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials. Lancet Respir Med. 2020 03; 8(3):247-257. Sinha P, Delucchi KL, McAuley DF, O'Kane CM, Matthay MA, Calfee CS. PMID: 31948926.
      View in: PubMed   Mentions: 10     Fields:    
    31. The authors reply. Crit Care Med. 2020 01; 48(1):e78. Rogers AJ, Desai M, Matthay MA, Choi AM, Baron RM. PMID: 31833991.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020 01 01; 201(1):47-56. Jones TK, Feng R, Kerchberger VE, Reilly JP, Anderson BJ, Shashaty MGS, Wang F, Dunn TG, Riley TR, Abbott J, Ittner CAG, Christiani DC, Mikacenic C, Wurfel MM, Ware LB, Calfee CS, Matthay MA, Christie JD, Meyer NJ. PMID: 31487195.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study. Crit Care. 2019 12 09; 23(1):400. Anderson BJ, Calfee CS, Liu KD, Reilly JP, Kangelaris KN, Shashaty MGS, Lazaar AL, Bayliffe AI, Gallop RJ, Miano TA, Dunn TG, Johansson E, Abbott J, Jauregui A, Deiss T, Vessel K, Belzer A, Zhuo H, Matthay MA, Meyer NJ, Christie JD. PMID: 31818332.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury. PLoS One. 2019; 14(11):e0225601. Kwong YD, Chen S, Bouajram R, Li F, Matthay MA, Mehta KM, Glidden DV, Liu KD. PMID: 31770424.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Therapeutic Effects of Hyaluronic Acid in Bacterial Pneumonia in Ex Vivo Perfused Human Lungs. Am J Respir Crit Care Med. 2019 11 15; 200(10):1234-1245. Liu A, Park JH, Zhang X, Sugita S, Naito Y, Lee JH, Kato H, Hao Q, Matthay MA, Lee JW. PMID: 31390880.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    36. Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. Theranostics. 2019; 9(26):8155-8170. Zhao R, Ali G, Chang J, Komatsu S, Tsukasaki Y, Nie HG, Chang Y, Zhang M, Liu Y, Jain K, Jung BG, Samten B, Jiang D, Liang J, Ikebe M, Matthay MA, Ji HL. PMID: 31754387.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    37. Lung inflammatory environments differentially alter mesenchymal stromal cell behavior. Am J Physiol Lung Cell Mol Physiol. 2019 12 01; 317(6):L823-L831. Abreu SC, Rolandsson Enes S, Dearborn J, Goodwin M, Coffey A, Borg ZD, Dos Santos CC, Wargo MJ, Cruz FF, Loi R, DeSarno M, Ashikaga T, Antunes MA, Rocco PRM, Liu KD, Lee JW, Matthay MA, McKenna DH, Weiss DJ. PMID: 31553626.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    38. Clinically relevant model of pneumococcal pneumonia, ARDS, and nonpulmonary organ dysfunction in mice. Am J Physiol Lung Cell Mol Physiol. 2019 11 01; 317(5):L717-L736. Gotts JE, Bernard O, Chun L, Croze RH, Ross JT, Nesseler N, Wu X, Abbott J, Fang X, Calfee CS, Matthay MA. PMID: 31509438.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    39. Plasma total fibroblast growth factor 23 levels are associated with acute kidney injury and mortality in children with acute respiratory distress syndrome. PLoS One. 2019; 14(9):e0222065. Hanudel MR, Zinter MS, Chen L, Gala K, Lim M, Guglielmo M, Deshmukh T, Vangala S, Matthay M, Sapru A. PMID: 31487315.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. A Multicenter Study of the Causes and Consequences of Optimistic Expectations About Prognosis by Surrogate Decision-Makers in ICUs. Crit Care Med. 2019 09; 47(9):1184-1193. White DB, Carson S, Anderson W, Steingrub J, Bird G, Curtis JR, Matthay M, Peterson M, Buddadhumaruk P, Shields AM, Ernecoff N, Shotsberger K, Weissfeld L, Chang CH, Pike F, Lo B, Hough CL. PMID: 31162200.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome. Crit Care Med. 2019 08; 47(8):1089-1096. Rogers AJ, Guan J, Trtchounian A, Hunninghake GM, Kaimal R, Desai M, Kozikowski LA, DeSouza L, Mogan S, Liu KD, Matthay MA, Steingrub J, Wheeler A, Yoon JH, Nakahira K, Choi AM, Baron RM. PMID: 31206358.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    42. The Continued Need for Clinical Trials in Deceased Organ Donor Management. Transplantation. 2019 07; 103(7):1298-1299. Niemann CU, Matthay MA, Ware LB. PMID: 30399123.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. The ex vivo human lung: research value for translational science. JCI Insight. 2019 06 06; 4(11). Ross JT, Nesseler N, Lee JW, Ware LB, Matthay MA. PMID: 31167972.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction. Respir Care. 2019 Sep; 64(9):1101-1108. Papolos AI, Schiller NB, Belzer A, Zhuo H, Gotts JE, Bibby D, Calfee CS, Matthay MA. PMID: 31138736.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Pathogenesis of Acute Respiratory Distress Syndrome. Semin Respir Crit Care Med. 2019 02; 40(1):31-39. Huppert LA, Matthay MA, Ware LB. PMID: 31060086.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    46. Clinician-Family Communication About Patients' Values and Preferences in Intensive Care Units. JAMA Intern Med. 2019 05 01; 179(5):676-684. Scheunemann LP, Ernecoff NC, Buddadhumaruk P, Carson SS, Hough CL, Curtis JR, Anderson WG, Steingrub J, Lo B, Matthay M, Arnold RM, White DB. PMID: 30933293.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. Is a Part Better than the Whole for Cell-based Therapy for Acute Respiratory Distress Syndrome? Anesthesiology. 2019 May; 130(5):683-685. Lee JW, Matthay MA. PMID: 30870157.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    48. A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome. Crit Care. 2019 04 17; 23(1):128. Flori H, Sapru A, Quasney MW, Gildengorin G, Curley MAQ, Matthay MA, Dahmer MK. PMID: 30995942.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. Precision medicine for cell therapy in acute respiratory distress syndrome - Authors' reply. Lancet Respir Med. 2019 04; 7(4):e14. Matthay MA, Zhuo H, Gotts JE, Liu KD, Calfee CS. PMID: 30926051.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    50. The authors reply. Crit Care Med. 2019 04; 47(4):e375-e376. Fielding-Singh V, Matthay MA, Calfee CS. PMID: 30882440.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. The authors reply. Crit Care Med. 2019 04; 47(4):e380-e381. Fielding-Singh V, Matthay MA, Calfee CS. PMID: 30882446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Could Decisions to Limit Treatment Contribute to Mortality Differences between Patients with Different Presepsis Trajectories? Ann Am Thorac Soc. 2019 04; 16(4):522. Block BL, Matthay M. PMID: 30495973.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    53. Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury. Pediatr Crit Care Med. 2019 04; 20(4):323-331. Zinter MS, Spicer AC, Liu KD, Orwoll BE, Alkhouli MF, Brakeman PR, Calfee CS, Matthay MA, Sapru A. PMID: 30672838.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Identification of Acute Kidney Injury Subphenotypes with Differing Molecular Signatures and Responses to Vasopressin Therapy. Am J Respir Crit Care Med. 2019 04 01; 199(7):863-872. Bhatraju PK, Zelnick LR, Herting J, Katz R, Mikacenic C, Kosamo S, Morrell ED, Robinson-Cohen C, Calfee CS, Christie JD, Liu KD, Matthay MA, Hahn WO, Dmyterko V, Slivinski NSJ, Russell JA, Walley KR, Christiani DC, Liles WC, Himmelfarb J, Wurfel MM. PMID: 30334632.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019 03 14; 5(1):18. Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS. PMID: 30872586.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    56. Heterogeneity in sepsis: new biological evidence with clinical applications. Crit Care. 2019 Mar 09; 23(1):80. Leligdowicz A, Matthay MA. PMID: 30850013.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    57. AIMing Immunomodulation Therapy at Sepsis. Am J Respir Cell Mol Biol. 2019 Mar; 60(3):253-254. Leligdowicz A, Matthay MA. PMID: 30365342.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    58. Prospective Assessment of the Feasibility of a Trial of Low-Tidal Volume Ventilation for Patients with Acute Respiratory Failure. Ann Am Thorac Soc. 2019 03; 16(3):356-362. Lanspa MJ, Gong MN, Schoenfeld DA, Lee KT, Grissom CK, Hou PC, Serpa-Neto A, Brown SM, Iwashyna TJ, Yealy DM, Hough CL, Brower RG, Calfee CS, Hyzy RC, Matthay MA, Miller RR, Steingrub JS, Thompson BT, Miller CD, Clemmer TP, Hendey GW, Huang DT, Mathews KS, Qadir N, Tidswell M. PMID: 30407869.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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    61. ECMO in severe acute respiratory distress syndrome. Lancet Respir Med. 2019 02; 7(2):106-108. Matthay MA. PMID: 30642777.
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    62. Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma. Am J Respir Crit Care Med. 2019 01 01; 199(1):62-70. Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB. PMID: 30067389.
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    70. Interleukin-1 Receptor Antagonist Is Associated With Pediatric Acute Respiratory Distress Syndrome and Worse Outcomes in Children With Acute Respiratory Failure. Pediatr Crit Care Med. 2018 10; 19(10):930-938. Dahmer MK, Quasney MW, Sapru A, Gildengorin G, Curley MAQ, Matthay MA, Flori H. PMID: 30095747.
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    72. Assessment of industry data on pulmonary and immunosuppressive effects of IQOS. Tob Control. 2018 11; 27(Suppl 1):s20-s25. Moazed F, Chun L, Matthay MA, Calfee CS, Gotts J. PMID: 30158203.
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    148. The acute respiratory distress syndrome following isolated severe traumatic brain injury. J Trauma Acute Care Surg. 2016 06; 80(6):989-97. Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ. PMID: 26881489.
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    149. Sepsis: pathophysiology and clinical management. BMJ. 2016 05 23; 353:i1585. Gotts JE, Matthay MA. PMID: 27217054.
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    151. Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2016 May 15; 193(10):1143-50. Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. PMID: 26681363.
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    156. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):3621-6. Chan MC, Kuok DI, Leung CY, Hui KP, Valkenburg SA, Lau EH, Nicholls JM, Fang X, Guan Y, Lee JW, Chan RW, Webster RG, Matthay MA, Peiris JS. PMID: 26976597.
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    158. Acute Hypoxemic Respiratory Failure after Large-Volume Thoracentesis. Mechanisms of Pleural Fluid Formation and Reexpansion Pulmonary Edema. Ann Am Thorac Soc. 2016 Mar; 13(3):438-43. Walter JM, Matthay MA, Gillespie CT, Corbridge T. PMID: 26963356.
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    159. New Strategies for Effective Therapeutics in Critically Ill Patients. JAMA. 2016 Feb 23; 315(8):747-8. Matthay MA, Liu KD. PMID: 26903328.
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    160. Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation. Thorax. 2016 12; 71(12):1130-1136. Moazed F, Burnham EL, Vandivier RW, O'Kane CM, Shyamsundar M, Hamid U, Abbott J, Thickett DR, Matthay MA, McAuley DF, Calfee CS. PMID: 26839359.
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    161. Acute cor pulmonale and the acute respiratory distress syndrome. Intensive Care Med. 2016 May; 42(5):934-936. Guérin C, Matthay MA. PMID: 26759013.
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    163. Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study. Crit Care. 2015 Dec 14; 19:435. Orwoll BE, Spicer AC, Zinter MS, Alkhouli MF, Khemani RG, Flori HR, Neuhaus JM, Calfee CS, Matthay MA, Sapru A. PMID: 26652251.
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    165. Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med. 2015 Sep; 43(9):1790-7. Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. PMID: 26010690.
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    173. Sedation protocol for critically ill pediatric patients--reply. JAMA. 2015 May 05; 313(17):1754-5. Curley MA, Wypij D, Matthay MA. PMID: 25942731.
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    175. Microvesicles Derived From Human Mesenchymal Stem Cells Restore Alveolar Fluid Clearance in Human Lungs Rejected for Transplantation. Am J Transplant. 2015 Sep; 15(9):2404-12. Gennai S, Monsel A, Hao Q, Park J, Matthay MA, Lee JW. PMID: 25847030.
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    290. Clinical review: Thinking outside the box--an iconoclastic view of current practice. Crit Care. 2011 Jul 26; 15(4):225. Singer M, Matthay MA. PMID: 21888690.
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    291. Claudin-4 levels are associated with intact alveolar fluid clearance in human lungs. Am J Pathol. 2011 Sep; 179(3):1081-7. Rokkam D, Lafemina MJ, Lee JW, Matthay MA, Frank JA. PMID: 21741940.
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