Michael Matthay, MD

Title(s)Recall Faculty, Medicine
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSE, #760
San Francisco CA 94143
Phone415-353-1206
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    Collapse Biography 
    Collapse education and training
    Harvard UniversityA.B.1969English
    University of PennsylvaniaM.D.1973School of Medicine
    University of Colorado Medical CenterInternship and Residency1976Internal Medicine
    University of California, San FranciscoFellowship1978Pulmonary DIvision
    University of California, San FranciscoFellowship1979Cardiovascular Research Institute
    Collapse awards and honors
    Cell Therapy Trauma & Critical Care Society2022Lifetime Achievements in Research
    Critical Care Society, Milan, Italy2019SMART award for Innovative Research
    UCSF2016Resident Molecular Medicine Mentor of the Year

    Collapse Overview 
    Collapse overview
    Dr. Matthay's overall focus is on improving clinical care of patients with acute respiratory failure from the acute respiratory distress syndrome and from sepsis. His research and clinical trials groups are very well funded by grants from the National Institute of Health. He also spends considerable time mentoring physicians and young faculty in career development and academic medicine.

    Collapse Research 
    Collapse research activities and funding
    1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)
    NIH UH3HL141722Sep 23, 2019 - Aug 31, 2024
    Role: Co-Principal Investigator
    1/1: ARREST RESPIRATORY FAILURE DUE TO PNEUMONIA (ARREST PNEUMONIA)
    NIH UG3HL141722Sep 23, 2019 - Aug 31, 2020
    Role: Co-Principal Investigator
    Prevention and Early Treatment of Acute Lung Injury
    NIH U01HL123004Jun 17, 2014 - Apr 30, 2021
    Role: Principal Investigator
    Allogeneic Human Mesenchymal Stem Cells for the Treatment of Acute Lung Injury
    NIH U01HL108713Sep 1, 2011 - Jun 30, 2018
    Role: Principal Investigator
    Title: Long-Term Oxygen Treatment Trial (LOTT) - Data Coordinating Center
    NIH N01HR000000Jan 3, 2011 - Dec 31, 2015
    Role: Co-Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-16-0-1Sep 30, 2005 - Jul 15, 2013
    Role: Principal Investigator
    ARDS - SAILS Protocol
    NIH N01HR56166-16-0-4Sep 30, 2005 - Jul 15, 2013
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH/NHLBI N01HR56166-14-0-1Sep 30, 2005 - Oct 31, 2012
    Role: Principal Investigator
    ARDS - SAILS Protocol
    NIH/NHLBI N01HR56166-14-0-4Sep 30, 2005 - Oct 31, 2012
    Role: Principal Investigator
    ARDS - ALTA Protocol
    NIH/NHLBI N01HR56166Sep 30, 2005 - Sep 29, 2012
    Role: Co-Principal Investigator
    ARDS - EDEN Protocol
    NIH N01HR56166-6-0-3Sep 30, 2005 - Sep 29, 2012
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-7-0-1Sep 30, 2005 - Sep 29, 2012
    Role: Principal Investigator
    Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
    NIH N01HR56166-9-0-1Sep 30, 2005 - Nov 30, 2011
    Role: Principal Investigator
    Transfusion and Lung Injury
    NIH P50HL081027Sep 30, 2005 - Aug 31, 2011
    Role: Co-Investigator
    SCCOR in translational research in Acute Lung Injury
    NIH P50HL074005Sep 30, 2003 - Jun 30, 2010
    Role: Principal Investigator
    Mucosal Immune Barrier in Infection and Immunity
    NIH P01AI053194Sep 30, 2002 - Aug 31, 2014
    Role: Co-Investigator
    Resolution of Clinical Lung Injury
    NIH R37HL051856Apr 1, 1996 - Mar 31, 2018
    Role: Principal Investigator
    RESOLUTION OF CLINICAL LUNG INJURY
    NIH R01HL051856Apr 1, 1996 - Mar 31, 2006
    Role: Principal Investigator
    CCTG CLINICAL NETWORK FOR ARDS TREATMENT--CRITICAL CARE
    NIH/NHLBI N01HR046059Sep 30, 1994 - Sep 29, 2001
    Role: Principal Investigator
    Lung Fluid Balance and Mesenchymal Stem Cells
    NIH R01HL051854Apr 8, 1994 - Jun 30, 2014
    Role: Principal Investigator
    ALVEOLAR EPITHELIAL LIQUID AND PROTEIN CLEARANCE
    NIH R01HL040626Jun 1, 1988 - Nov 30, 1989
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    PATHOPHYSIOLOGY OF LUNG LIQUID &PROTEIN EXCHANGE
    NIH P01HL025816Jun 1, 1980 - May 31, 1994
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Plasma Soluble Intercellular Adhesion Molecule-1 Has a Central Role in Biomarker Network Analysis and Is Associated With Poor Outcomes in Two Distinct Pediatric Cohorts of Acute Respiratory Distress Syndrome and Acute Respiratory Failure. Crit Care Med. 2025 Jun 03. Lim MJ, Whitney JE, Sallee CJ, Markovic D, Bera A, Sinha P, Zeigler A, Chen L, Zinter MS, Ali A, Matthay MA, Schwingshackl A, Agus MSD, Sapru A, Pediatric Acute Lung Injury (PALI) and Coagulation and Fibrinolysis in Pediatric Insulin Titration T. PMID: 40459371.
      View in: PubMed   Mentions:
    2. Elastance May Determine the Neuromuscular Blockade Effect on Mortality in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2025 Jun; 211(6):966-974. Zalucky AA, Dianti J, Neyton LPA, Sinha P, Liu KD, Matthay MA, Thompson BT, Goligher EC, Calfee CS. PMID: 39998496.
      View in: PubMed   Mentions:    Fields:    
    3. Awake Prone Positioning in COVID-19-Is There a New Standard of Care? JAMA Intern Med. 2025 May 01; 185(5):581-582. Matthay MA, Wick KD, Alipanah-Lechner N. PMID: 40063032.
      View in: PubMed   Mentions:    Fields:    
    4. Beyond immunosuppression: decoding systemic immune dysregulation in ICU-acquired pneumonia. Eur Respir J. 2025 Apr; 65(4). Neyton LPA, Matthay MA, Dela Cruz CS, Rizzo AN. PMID: 40274294.
      View in: PubMed   Mentions:    Fields:    
    5. A randomized trial of open lung protective ventilation compared to conventional mechanical ventilation in deceased organ donors. J Heart Lung Transplant. 2025 Apr 03. Ware LB, Koyama T, Shaver CM, Swain S, Nguyen J, Salehi A, Dhillon G, Wickersham N, Maheshwari J, Singer JP, Weigt SS, Kukreja J, Matthay MA. PMID: 40187505.
      View in: PubMed   Mentions:    Fields:    
    6. Endothelial ENaC-α Restrains Oxidative Stress in Lung Capillaries in Murine Pneumococcal Pneumonia-associated Acute Lung Injury. Am J Respir Cell Mol Biol. 2025 Apr; 72(4):429-440. Romero MJ, Yue Q, Ahn WM, Hamacher J, Zaidi Y, Haigh S, Sridhar S, Gonzales J, Hudel M, Huo Y, Verin AD, Pace BS, Stansfield BK, Maishan M, Neptune ER, Enkhbaatar P, Su Y, Chakraborty T, Gonsalvez G, Hummler E, Davis WB, Bogdanov VY, Fulton DJR, Csanyi G, Matthay MA, Eaton DC, Lucas R. PMID: 39405473; PMCID: PMC12005010.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    7. Gut bacterial lactate stimulates lung epithelial mitochondria and exacerbates acute lung injury. bioRxiv. 2025 Mar 25. Upadhyay V, Ortega EF, Ramirez Hernandez LA, Alexander M, Kaur G, Trepka K, Rock RR, Shima RT, Cheshire WC, Alipanah-Lechner N, Calfee CS, Matthay MA, Lee JV, Goga A, Jain IH, Turnbaugh PJ. PMID: 40196632; PMCID: PMC11974820.
      View in: PubMed   Mentions:
    8. Temporal Transitions of the Hyperinflammatory and Hypoinflammatory Phenotypes in Critical Illness. Am J Respir Crit Care Med. 2025 Mar; 211(3):347-356. van Amstel RBE, Bartek B, Vlaar APJ, Gay E, van Vught LA, Cremer OL, Van der Poll T, Shapiro NI, Matthay MA, Calfee CS, Sinha P, Bos LDJ. PMID: 39642348; PMCID: PMC11936145.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Unlocking the Therapeutic Code of Mesenchymal Stromal Cells. Am J Respir Crit Care Med. 2025 Mar; 211(3):313-315. Lingappan K, Matthay MA. PMID: 39847724; PMCID: PMC11936120.
      View in: PubMed   Mentions:    Fields:    
    10. Agreement between Sepsis-2 and Sepsis-3 Definitions among Patients Admitted to the Intensive Care Unit. Ann Am Thorac Soc. 2025 Mar; 22(3):460-462. Zalucky AA, Evrard B, Delucchi K, Zhuo H, Wu N, Liu KD, Hendrickson CM, Matthay MA, Kangelaris KN, Calfee CS. PMID: 39471317; PMCID: PMC11892669.
      View in: PubMed   Mentions:    Fields:    
    11. Acute respiratory distress vs healthy lung environments differently affect mesenchymal stromal cell extracellular vesicle miRNAs. Cytotherapy. 2025 May; 27(5):581-596. Rolandsson Enes S, Dzneladze I, Hampton TH, Neff SL, Asarian L, Barua J, Tertel T, Giebel B, Pereyra N, McKenna DH, Hu P, Acton E, Ashare A, Liu KD, Krasnodembskaya AD, English K, Stanton BA, Rocco PRM, Matthay MA, Dos Santos CC, Weiss DJ. PMID: 39945694.
      View in: PubMed   Mentions:    Fields:    
    12. Anti-CD14 treatment in patients with severe COVID-19: Clinical and biological effects in a Phase 2 randomized open-label adaptive platform clinical trial. CHEST Crit Care. 2025 Mar; 3(1). Mabrey FL, Martin TR, Calfee CS, Liu KD, LaCombe B, Brown-Swigart L, Discacciati A, Eklund M, Heckbert SR, Matthay MA, Esserman L, Wurfel MM. PMID: 40462830; PMCID: PMC12129406.
      View in: PubMed   Mentions:
    13. Pneumothoraces Associated With Vaping Cannabis Concentrate. Pediatrics. 2024 Nov 01; 154(5). Olgin GK, Ludwig C, Matthay MA, Gribben V. PMID: 39468959.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    14. Delphi-driven consensus definition for mesenchymal stromal cells and clinical reporting guidelines for mesenchymal stromal cell-based therapeutics. Cytotherapy. 2025 Feb; 27(2):146-168. Renesme L, Cobey KD, Lalu MM, Bubela T, Chinnadurai R, De Vos J, Dunbar R, Fergusson D, Freund D, Galipeau J, Horwitz E, Lê M, Matthay M, Moher D, Nolta J, Parker G, Phinney DG, Rao M, Rasko JEJ, Rocco PRM, Rossi F, Myles MR, Viswanathan S, Thébaud B. PMID: 39580717.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia. Nat Commun. 2024 Oct 29; 15(1):9339. Spottiswoode N, Tsitsiklis A, Chu VT, Phan HV, DeVoe C, Love C, Ghale R, Bloomstein J, Zha BS, Maguire CP, Glascock A, Sarma A, Mourani PM, Kalantar KL, Detweiler A, Neff N, Haller SC, COMET Consortium, DeRisi JL, Erle DJ, Hendrickson CM, Kangelaris KN, Krummel MF, Matthay MA, Woodruff PG, Calfee CS, Langelier CR. PMID: 39472555; PMCID: PMC11522429.
      View in: PubMed   Mentions:    Fields:    
    16. Acute respiratory distress syndrome. BMJ. 2024 10 28; 387:e076612. Wick KD, Ware LB, Matthay MA. PMID: 39467606.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Biomarkers of Acute Respiratory Distress Syndrome: Current State and Future Prospects. Clin Chest Med. 2024 Dec; 45(4):809-820. Zalucky AA, Matthay MA, Ware LB. PMID: 39442999.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Definitions of Acute Respiratory Distress Syndrome: Present Recommendations and Challenges. Clin Chest Med. 2024 Dec; 45(4):785-795. Jayasimhan D, Matthay MA. PMID: 39442997.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial. JAMA. 2024 08 06; 332(5):390-400. Ware LB, Files DC, Fowler A, Aboodi MS, Aggarwal NR, Brower RG, Chang SY, Douglas IS, Fields S, Foulkes AS, Ginde AA, Harris ES, Hendey GW, Hite RD, Huang W, Lai P, Liu KD, Thompson BT, Matthay MA, National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinic. PMID: 38762798; PMCID: PMC11304120.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    20. Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading. bioRxiv. 2024 Jul 31. Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, Pan S, Nilsson J, Yin X, Bhattacharyya A, Boostanpour K, Jujaray T, Wang J, Tsukui T, Sheppard D, Li B, Maishan M, Taenaka H, Matthay MA, Muramatsu R, Maliskova L, Ghosh A, Eckalbar WL, Molofsky AB, Wolters PJ, Tamaki SJ, Bivona T, Abate AR, Wagner A, Tharp KM, Bhattacharya M. PMID: 39211079; PMCID: PMC11360891.
      View in: PubMed   Mentions:
    21. Immediate myeloid depot for SARS-CoV-2 in the human lung. Sci Adv. 2024 Aug 02; 10(31):eadm8836. Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Bernard O, Simoneau CR, Hysenaj L, Hu KH, Maishan M, Conrad C, Gbenedio OM, Samad B, Consortium TUC, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. PMID: 39083602; PMCID: PMC11290487.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    22. Longitudinal importance of the soluble receptor for advanced glycation end-products in nonintubated hospitalized patients with COVID-19 pneumonia. Am J Physiol Lung Cell Mol Physiol. 2024 Nov 01; 327(5):L607-L614. Wick KD, Siegel L, Oldmixon C, Lundgren JD, Thompson BT, Jones C, Leroux C, Matthay MA, ACTIV-3/TICO Study Group. PMID: 39076084; PMCID: PMC11563646.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. Use of modified Berlin criteria in identifying patients with acute respiratory distress syndrome: a single-centre retrospective cohort study. Br J Anaesth. 2024 Sep; 133(3):700-703. Thompson JH, Reddy K, Matthay MA, McAuley DF, Simpson AJ, Rostron AJ. PMID: 39019768.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Long-term air pollution exposure and the risk of primary graft dysfunction after lung transplantation. J Heart Lung Transplant. 2025 Jan; 44(1):64-74. Koyama T, Zhao Z, Balmes JR, Calfee CS, Matthay MA, Reilly JP, Porteous MK, Diamond JM, Christie JD, Cantu E, Ware LB, Lung Transplant Outcomes Group. PMID: 39019353.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    25. A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. J Clin Invest. 2024 Jul 09; 134(18). Cohen ML, Brumwell AN, Ho TC, Garakani K, Montas G, Leong D, Ding VW, Golden JA, Trinh BN, Jablons DM, Matthay MA, Jones KD, Wolters PJ, Wei Y, Chapman HA, Le Saux CJ. PMID: 38980870; PMCID: PMC11405054.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    26. 11β hydroxysteroid dehydrogenase type 1 transgenic mesenchymal stem cells attenuate inflammation in models of sepsis. Front Bioeng Biotechnol. 2024; 12:1422761. Mahida RY, Yuan Z, Kolluri KK, Scott A, Parekh D, Hardy RS, Matthay MA, Perkins GD, Janes SM, Thickett DR. PMID: 39036559; PMCID: PMC11257926.
      View in: PubMed   Mentions:
    27. NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids. Sci Rep. 2024 07 04; 14(1):15351. Simoneau CR, Chen PY, Xing GK, Hayashi JM, Chen IP, Khalid MM, Meyers NL, Taha TY, Leon KE, Suryawanshi RK, McCavitt-Malvido M, Ashuach T, Fontaine KA, Rodriguez L, Joehnk B, Walcott K, Vasudevan S, Fang X, Maishan M, Schultz S, Roose JP, Matthay MA, Sil A, Arjomandi M, Yosef N, Ott M. PMID: 38961189; PMCID: PMC11222426.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    28. Vagal-α7 nicotinic acetylcholine receptor signaling exacerbates influenza severity by promoting lung epithelial cell infection. J Med Virol. 2024 Jul; 96(7):e29768. Zhao C, Pan M, Chen J, Li L, Zhang Y, Liu W, Matthay MA, Wang H, Jin X, Xu JF, Su X. PMID: 38978388.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Incidence of acute kidney injury and attributive mortality in acute respiratory distress syndrome randomized trials. Intensive Care Med. 2024 Aug; 50(8):1240-1250. Antonucci E, Garcia B, Chen D, Matthay MA, Liu KD, Legrand M. PMID: 38864911; PMCID: PMC11306535.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    30. Biological effects of corticosteroids on pneumococcal pneumonia in Mice-translational significance. Crit Care. 2024 05 29; 28(1):185. Taenaka H, Wick KD, Sarma A, Matsumoto S, Ghale R, Fang X, Maishan M, Gotts JE, Langelier CR, Calfee CS, Matthay MA. PMID: 38807178; PMCID: PMC11134653.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    31. Early trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study. Lancet Microbe. 2024 Jun; 5(6):e559-e569. Jensen TO, Murray TA, Grandits GA, Jain MK, Grund B, Shaw-Saliba K, Matthay MA, Abassi M, Ardelt M, Baker JV, Chen P, Dewar RL, Goodman AL, Hatlen TJ, Highbarger HC, Holodniy M, Lallemand P, Laverdure S, Leshnower BG, Looney D, Moschopoulos CD, Mugerwa H, Murray DD, Mylonakis E, Nagy-Agren S, Rehman MT, Rupert A, Stevens R, Turville S, Weintrob A, Wick K, Lundgren J, Ko ER, ACTIV-3/TICO Study Group. PMID: 38815595; PMCID: PMC11181148.
      View in: PubMed   Mentions: 2     Fields:    
    32. Neutrophil reduction attenuates the severity of lung injury in the early phase of pneumococcal pneumonia in mice. Am J Physiol Lung Cell Mol Physiol. 2024 Aug 01; 327(2):L141-L149. Taenaka H, Fang X, Maishan M, Trivedi A, Wick KD, Gotts JE, Martin TR, Calfee CS, Matthay MA. PMID: 38772909; PMCID: PMC11687957.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    33. Reply to Liufu et al. and to Palanidurai et al. Am J Respir Crit Care Med. 2024 05 15; 209(10):1280. Matthay MA, Ware LB, Riviello ED, Wick KD, Thompson T, Martin TR. PMID: 38507735; PMCID: PMC11146549.
      View in: PubMed   Mentions:    Fields:    
    34. Elevated Hemoglobin A1c and the Risk of Developing ARDS in Two Cohort Studies. CHEST Crit Care. 2024 Sep; 2(3). Bogart AM, Lopez CR, Obeidalla SN, Wang C, Willmore A, Jauregui A, Kangelaris KN, Hendrickson C, Gomez A, Liu KD, Matthay MA, Shaver CM, Bastarache JA, Calfee CS, Kerchberger VE, Ware LB. PMID: 39421542; PMCID: PMC11485198.
      View in: PubMed   Mentions:
    35. Causes and attributable fraction of death from ARDS in inflammatory phenotypes of sepsis. Crit Care. 2024 05 14; 28(1):164. Evrard B, Sinha P, Delucchi K, Hendrickson CM, Kangelaris KN, Liu KD, Willmore A, Wu N, Neyton L, Schmiege E, Gomez A, Kerchberger VE, Zalucky A, Matthay MA, Ware LB, Calfee CS. PMID: 38745253; PMCID: PMC11092165.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Life-saving effect of pulmonary surfactant in premature babies. J Clin Invest. 2024 May 01; 134(9). Raj JU, Bland RD, Bhattacharya J, Rabinovitch M, Matthay MA. PMID: 38690742; PMCID: PMC11060732.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome. Crit Care. 2024 04 23; 28(1):136. Baedorf-Kassis E, Murn M, Dzierba AL, Serra AL, Garcia I, Minus E, Padilla C, Sarge T, Goodspeed VM, Matthay MA, Gong MN, Cook D, Loring SH, Talmor D, Beitler JR, EPVent-2 Study Group. PMID: 38654391; PMCID: PMC11036740.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Rapidly improving ARDS differs clinically and biologically from persistent ARDS. Crit Care. 2024 04 22; 28(1):132. Valda Toro PL, Willmore A, Wu NE, Delucchi KL, Jauregui A, Sinha P, Liu KD, Hendrickson CM, Sarma A, Neyton LPA, Leligdowicz A, Langelier CR, Zhuo H, Jones C, Kangelaris KN, Gomez AD, Matthay MA, Calfee CS. PMID: 38649920; PMCID: PMC11034037.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia. Am J Respir Crit Care Med. 2024 04 15; 209(8):973-986. Chouchane O, Schuurman AR, Reijnders TDY, Peters-Sengers H, Butler JM, Uhel F, Schultz MJ, Bonten MJ, Cremer OL, Calfee CS, Matthay MA, Langley RJ, Alipanah-Lechner N, Kingsmore SF, Rogers A, van Weeghel M, Vaz FM, van der Poll T. PMID: 38240721; PMCID: PMC12039242.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    40. Timing of antibiotic treatment identifies distinct clinical presentations among patients presenting with suspected septic shock. J Am Coll Emerg Physicians Open. 2024 Apr; 5(2):e13149. Prasad PA, Esmaili AM, Oreper S, Beagle AJ, Hubbard C, Raffel KE, Abe-Jones Y, Fang MC, Liu KD, Matthay MA, Kangelaris KN. PMID: 38596320; PMCID: PMC11002635.
      View in: PubMed   Mentions: 1  
    41. Cell-based Therapies for Acute Respiratory Distress Syndrome: Where Are We Now? Am J Respir Crit Care Med. 2024 04 01; 209(7):789-797. Curley GF, O'Kane CM, McAuley DF, Matthay MA, Laffey JG. PMID: 38324017; PMCID: PMC10995569.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    42. Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally over Time. Am J Respir Crit Care Med. 2024 04 01; 209(7):816-828. Sinha P, Neyton L, Sarma A, Wu N, Jones C, Zhuo H, Liu KD, Sanchez Guerrero E, Ghale R, Love C, Mick E, Delucchi KL, Langelier CR, Thompson BT, Matthay MA, Calfee CS. PMID: 38345571; PMCID: PMC10995566.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    43. Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes. Am J Respir Crit Care Med. 2024 04 01; 209(7):805-815. Neyton LPA, Sinha P, Sarma A, Mick E, Kalantar K, Chen S, Wu N, Delucchi K, Zhuo H, Bos LDJ, Jauregui A, Gomez A, Hendrickson CM, Kangelaris KN, Leligdowicz A, Liu KD, Matthay MA, Langelier CR, Calfee CS. PMID: 38190719; PMCID: PMC10995577.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    44. Inter- and Intra-donor variability in bone marrow-derived mesenchymal stromal cells: implications for clinical applications. Cytotherapy. 2024 Sep; 26(9):1062-1075. Trivedi A, Lin M, Miyazawa B, Nair A, Vivona L, Fang X, Bieback K, Schäfer R, Spohn G, McKenna D, Zhuo H, Matthay MA, Pati S. PMID: 38852094.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19. J Infect Dis. 2024 Mar 14; 229(3):671-679. Jensen TO, Grandits GA, Jain MK, Murray TA, Grund B, Shaw-Saliba K, Matthay MA, Abassi M, Ardelt M, Baker JV, Chen P, Dewar RL, Goodman AL, Hatlen TJ, Highbarger HC, Holodniy M, Lallemand P, Laverdure S, Leshnower BG, Looney D, Moschopoulos CD, Mugerwa H, Murray DD, Mylonakis E, Nagy-Agren S, Rehman MT, Rupert A, Stevens RA, Turville S, Weintrob A, Wick K, Lundgren J, Ko ER, ACTIV-3/TICO Study Group . PMID: 37948759; PMCID: PMC10938202.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    46. The Translational Value of Rodent Models of Sepsis. Am J Respir Crit Care Med. 2024 03 01; 209(5):488-490. Matthay MA, Schmidt EP, Bastarache JA, Calfee CS, Frevert CW, Martin TR. PMID: 38091521; PMCID: PMC10919117.
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    96. Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19. Lancet Respir Med. 2022 07; 10(7):700-714. Casey JD, Beskow LM, Brown J, Brown SM, Gayat É, Ng Gong M, Harhay MO, Jaber S, Jentzer JC, Laterre PF, Marshall JC, Matthay MA, Rice TW, Rosenberg Y, Turnbull AE, Ware LB, Self WH, Mebazaa A, Collins SP. PMID: 35709825; PMCID: PMC9191864.
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    97. Impact of e-cigarette aerosol on primary human alveolar epithelial type 2 cells. Am J Physiol Lung Cell Mol Physiol. 2022 08 01; 323(2):L152-L164. Wick KD, Fang X, Maishan M, Matsumoto S, Spottiswoode N, Sarma A, Simoneau C, Khakoo M, Langelier C, Calfee CS, Gotts JE, Matthay MA. PMID: 35670478; PMCID: PMC9559034.
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    98. I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations. BMJ Open. 2022 06 06; 12(6):e060664. Files DC, Matthay MA, Calfee CS, Aggarwal NR, Asare AL, Beitler JR, Berger PA, Burnham EL, Cimino G, Coleman MH, Crippa A, Discacciati A, Gandotra S, Gibbs KW, Henderson PT, Ittner CAG, Jauregui A, Khan KT, Koff JL, Lang J, LaRose M, Levitt J, Lu R, McKeehan JD, Meyer NJ, Russell DW, Thomas KW, Eklund M, Esserman LJ, Liu KD, ISPY COVID Adaptive Platform Trial Network, undefined. PMID: 35667714; PMCID: PMC9170797.
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    99. Ventilatory Ratio Is a Valuable Prognostic Indicator in an Observational Cohort of Patients With ARDS. Respir Care. 2022 09; 67(9):1075-1081. Siegel ER, Zhuo H, Sinha P, Papolos AI, Ni SA, Vessel K, Belzer A, Minus EB, Calfee CS, Matthay MA, Wick KD. PMID: 35641002; PMCID: PMC9994339.
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    100. Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury. J Thromb Haemost. 2022 09; 20(9):2109-2118. Matthay ZA, Fields AT, Nunez-Garcia B, Park JJ, Jones C, Leligdowicz A, Hendrickson CM, Callcut RA, Matthay MA, Kornblith LZ. PMID: 35592998; PMCID: PMC10450647.
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    101. Proceedings of the ISCT scientific signature series symposium, "Advances in cell and gene therapies for lung diseases and critical illnesses": International Society for Cell & Gene Therapy, Burlington VT, US, July 16, 2021. Cytotherapy. 2022 08; 24(8):774-788. Ting AE, Baker EK, Champagne J, Desai TJ, Dos Santos CC, Heijink IH, Itescu S, Le Blanc K, Matthay MA, McAuley DF, McIntyre L, Mei SHJ, Parekkadan B, Rocco PRM, Sheridan J, Thébaud B, Weiss DJ. PMID: 35613962.
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    102. Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. Nature. 2022 07; 607(7918):351-355. Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. PMID: 35584773; PMCID: PMC9279157.
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    103. Immediate myeloid depot for SARS-CoV-2 in the human lung. Res Sq. 2022 May 17. Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Simoneau CR, Hysenaj L, Hu KH, UCSF COMET Consortium, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. PMID: 35611333; PMCID: PMC9128787.
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    109. Cigarette Smoke Exposure and Acute Respiratory Distress Syndrome in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. Am J Respir Crit Care Med. 2022 04 15; 205(8):927-935. Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. PMID: 35050845; PMCID: PMC9838633.
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    110. Aerosolized vitamin E acetate causes oxidative injury in mice and in alveolar macrophages. Am J Physiol Lung Cell Mol Physiol. 2022 06 01; 322(6):L771-L783. Matsumoto S, Traber MG, Leonard SW, Choi J, Fang X, Maishan M, Wick KD, Jones KD, Calfee CS, Gotts JE, Matthay MA. PMID: 35318859; PMCID: PMC9109788.
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    111. Pulmonary microbiome and gene expression signatures differentiate lung function in pediatric hematopoietic cell transplant candidates. Sci Transl Med. 2022 03 09; 14(635):eabm8646. Zinter MS, Versluys AB, Lindemans CA, Mayday MY, Reyes G, Sunshine S, Chan M, Fiorino EK, Cancio M, Prevaes S, Sirota M, Matthay MA, Kharbanda S, Dvorak CC, Boelens JJ, DeRisi JL. PMID: 35263147; PMCID: PMC9487170.
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    112. CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2022 04 01; 322(4):L617-L624. Mahida RY, Price J, Lugg ST, Li H, Parekh D, Scott A, Harrison P, Matthay MA, Thickett DR. PMID: 35234046; PMCID: PMC8993517.
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    113. Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness. Crit Care Med. 2022 03 01; 50(3):e284-e293. Mikacenic C, Bhatraju P, Robinson-Cohen C, Kosamo S, Fohner AE, Dmyterko V, Long SA, Cerosaletti K, Calfee CS, Matthay MA, Walley KR, Russell JA, Christie JD, Meyer NJ, Christiani DC, Wurfel MM. PMID: 34593707; PMCID: PMC8863632.
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    122. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022 02; 175(2):234-243. ACTIV-3/TICO Bamlanivimab Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Goodman AL, Chang W, Dewar RL, Gerry NP, Higgs ES, Highbarger H, Murray DD, Murray TA, Natarajan V, Paredes R, Parmar MKB, Phillips AN, Reilly C, Rupert AW, Sharma S, Shaw-Saliba K, Sherman BT, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Davey VJ, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD. PMID: 34928698; PMCID: PMC9334931.
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    123. Cell Therapy with the Cell or without the Cell for Premature Infants?: Time Will Tell. Am J Respir Crit Care Med. 2021 12 15; 204(12):1359-1361. Thébaud B, Matthay MA. PMID: 34752727; PMCID: PMC8865724.
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    124. Carbonic Anhydrase IX: Scaring Away the Grim Reaper in Acute Lung Injury? Am J Respir Cell Mol Biol. 2021 12; 65(6):573-575. Leligdowicz A, Matthay MA. PMID: 34375573; PMCID: PMC8641805.
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    125. Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19. medRxiv. 2021 Nov 30. Tsitsiklis A, Zha BS, Byrne A, DeVoe C, Rackaityte E, Levan S, Sunshine S, Mick E, Ghale R, Love C, Tarashansky AJ, Pisco A, Albright J, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Detweiler A, Jones NG, Wu B, Darmanis S, Lynch SV, DeRisi JL, COMET Consortium, Matthay MA, Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Rosenberg O, Calfee CS, Langelier CR. PMID: 33791731; PMCID: PMC8010763.
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    129. Molecular programs of fibrotic change in aging human lung. Nat Commun. 2021 11 02; 12(1):6309. Lee S, Islam MN, Boostanpour K, Aran D, Jin G, Christenson S, Matthay MA, Eckalbar WL, DePianto DJ, Arron JR, Magee L, Bhattacharya S, Matsumoto R, Kubota M, Farber DL, Bhattacharya J, Wolters PJ, Bhattacharya M. PMID: 34728633; PMCID: PMC8563941.
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    130. Delayed angiopoietin-2 blockade reduces influenza-induced lung injury and improves survival in mice. Physiol Rep. 2021 11; 9(21):e15081. Gotts JE, Maishan M, Chun L, Fang X, Han CY, Chiueh V, Khakoo AY, Lee T, Stolina M, Matthay MA. PMID: 34755490; PMCID: PMC8578883.
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    132. Healthy versus inflamed lung environments differentially affect mesenchymal stromal cells. Eur Respir J. 2021 10; 58(4). Rolandsson Enes S, Hampton TH, Barua J, McKenna DH, Dos Santos CC, Amiel E, Ashare A, Liu KD, Krasnodembskaya AD, English K, Stanton BA, Rocco PRM, Matthay MA, Weiss DJ. PMID: 33795318; PMCID: PMC8543758.
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    133. Environmental Factors. Crit Care Clin. 2021 Oct; 37(4):717-732. Wick KD, Matthay MA. PMID: 34548130; PMCID: PMC8462057.
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    134. Preface. Crit Care Clin. 2021 10; 37(4):xiii-xv. Matthay MA, Liu KD. PMID: 34548141; PMCID: PMC8449142.
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    139. IL-6 Receptor Antagonist Therapy for Patients Hospitalized for COVID-19: Who, When, and How? JAMA. 2021 08 10; 326(6):483-485. Matthay MA, Luetkemeyer AF. PMID: 34228779.
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    157. Fibrinolytic niche is required for alveolar type 2 cell-mediated alveologenesis via a uPA-A6-CD44+-ENaC signal cascade. Signal Transduct Target Ther. 2021 02 27; 6(1):97. Ali G, Zhang M, Zhao R, Jain KG, Chang J, Komatsu S, Zhou B, Liang J, Matthay MA, Ji HL. PMID: 33640905; PMCID: PMC7910758.
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    164. Biological Mechanisms of COVID-19 Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020 12 01; 202(11):1489-1491. Matthay MA, Leligdowicz A, Liu KD. PMID: 32997945; PMCID: PMC7706166.
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    180. Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells. Am J Physiol Lung Cell Mol Physiol. 2020 12 01; 319(6):L908-L925. Abreu SC, Hampton TH, Hoffman E, Dearborn J, Ashare A, Singh Sidhu K, Matthews DE, McKenna DH, Amiel E, Barua J, Krasnodembskaya A, English K, Mahon B, Dos Santos C, Cruz FF, Chambers DC, Liu KD, Matthay MA, Cramer RA, Stanton BA, Rocco PRM, Wargo MJ, Weiss DJ, Rolandsson Enes S. PMID: 32901521; PMCID: PMC7792680.
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    181. Is a "Cytokine Storm" Relevant to COVID-19? JAMA Intern Med. 2020 09 01; 180(9):1152-1154. Sinha P, Matthay MA, Calfee CS. PMID: 32602883.
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    182. Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care. NHLBI Working Group Report. Am J Respir Crit Care Med. 2020 Aug 15; 202(4):511-523. Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LA. PMID: 32150460; PMCID: PMC7427373.
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    184. Association of patient weight status with plasma surfactant protein D, a biomarker of alveolar epithelial injury, in children with acute respiratory failure. Pediatr Pulmonol. 2020 10; 55(10):2730-2736. Ward SL, Dahmer MK, Weeks HM, Sapru A, Quasney MW, Curley MAQ, Liu KD, Matthay MA, Flori HR. PMID: 32725941; PMCID: PMC8087214.
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    185. Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep. Am J Respir Crit Care Med. 2020 08 01; 202(3):383-392. Millar JE, Bartnikowski N, Passmore MR, Obonyo NG, Malfertheiner MV, von Bahr V, Redd MA, See Hoe L, Ki KK, Pedersen S, Boyle AJ, Baillie JK, Shekar K, Palpant N, Suen JY, Matthay MA, McAuley DF, Fraser JF. PMID: 32293914; PMCID: PMC7397785.
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    186. Higher plasma cystatin C is associated with mortality after acute respiratory distress syndrome: findings from a Fluid and Catheter Treatment Trial (FACTT) substudy. Crit Care. 2020 07 11; 24(1):416. Hendrickson CM, Kwong YD, Belzer AG, Shlipak MG, Matthay MA, Liu KD. PMID: 32653023; PMCID: PMC7353675.
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    187. Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2020 07; 63(1):15-24. Mahida RY, Matsumoto S, Matthay MA. PMID: 32109144; PMCID: PMC7328246.
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    188. The ex vivo perfused human lung is resistant to injury by high-dose S. pneumoniae bacteremia. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L218-L227. Ross JT, Nesseler N, Leligdowicz A, Zemans RL, Mahida RY, Minus E, Langelier C, Gotts JE, Matthay MA. PMID: 32519893; PMCID: PMC7473934.
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    189. Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time. Crit Care Med. 2020 06; 48(6):830-837. Schwede M, Lee RY, Zhuo H, Kangelaris KN, Jauregui A, Vessel K, Belzer A, Deiss T, Matthay MA, Liu KD, Calfee CS. PMID: 32317598; PMCID: PMC7335674.
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    190. Impact of Bilateral Infiltrates on Inflammatory Biomarker Levels and Clinical Outcomes of Children With Oxygenation Defect. Crit Care Med. 2020 06; 48(6):e498-e504. Kohne JG, Dahmer MK, Weeks HM, Kaciroti N, Quasney MW, Sapru A, Curley MAQ, Matthay M, Flori H. PMID: 32317601; PMCID: PMC10910885.
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    191. Plasmin improves blood-gas barrier function in oedematous lungs by cleaving epithelial sodium channels. Br J Pharmacol. 2020 07; 177(13):3091-3106. Zhao R, Ali G, Nie HG, Chang Y, Bhattarai D, Su X, Zhao X, Matthay MA, Ji HL. PMID: 32133621; PMCID: PMC7280014.
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    192. Patterns and Trends in Advance Care Planning Among Older Adults Who Received Intensive Care at the End of Life. JAMA Intern Med. 2020 05 01; 180(5):786-789. Block BL, Jeon SY, Sudore RL, Matthay MA, Boscardin WJ, Smith AK. PMID: 32119031; PMCID: PMC7052782.
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    193. The potential of lipid mediator networks as ocular surface therapeutics and biomarkers. Ocul Surf. 2021 01; 19:104-114. Flitter BA, Fang X, Matthay MA, Gronert K. PMID: 32360792; PMCID: PMC7606340.
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    194. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun. 2020 04 21; 11(1):1920. Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. PMID: 32317643; PMCID: PMC7174390.
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    195. Surfactant Protein D Is Associated With Severe Pediatric ARDS, Prolonged Ventilation, and Death in Children With Acute Respiratory Failure. Chest. 2020 09; 158(3):1027-1035. Dahmer MK, Flori H, Sapru A, Kohne J, Weeks HM, Curley MAQ, Matthay MA, Quasney MW, BALI and RESTORE Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALIS. PMID: 32275979; PMCID: PMC7478231.
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    197. Gender Differences in Authorship of Critical Care Literature. Am J Respir Crit Care Med. 2020 04 01; 201(7):840-847. Vranas KC, Ouyang D, Lin AL, Slatore CG, Sullivan DR, Kerlin MP, Liu KD, Baron RM, Calfee CS, Ware LB, Halpern SD, Matthay MA, Herridge MS, Mehta S, Rogers AJ. PMID: 31968182; PMCID: PMC7124723.
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    198. Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility. Physiol Rev. 2020 07 01; 100(3):1065-1075. Ji HL, Zhao R, Matalon S, Matthay MA. PMID: 32216698; PMCID: PMC7191627.
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    200. Treatment for severe acute respiratory distress syndrome from COVID-19. Lancet Respir Med. 2020 05; 8(5):433-434. Matthay MA, Aldrich JM, Gotts JE. PMID: 32203709; PMCID: PMC7118607.
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    201. Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study. J Thorac Cardiovasc Surg. 2020 Nov; 160(5):1385-1395.e6. Hamilton BCS, Dincheva GR, Matthay MA, Hays S, Singer JP, Brzezinski M, Kukreja J. PMID: 32252988; PMCID: PMC7485564.
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    203. Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop. Intensive Care Med. 2020 05; 46(5):930-942. Harhay MO, Casey JD, Clement M, Collins SP, Gayat É, Gong MN, Jaber S, Laterre PF, Marshall JC, Matthay MA, Monroe RE, Rice TW, Rubin E, Self WH, Mebazaa A. PMID: 32072303; PMCID: PMC7224097.
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    204. Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. Crit Care Med. 2020 02; 48(2):200-209. Prasad PA, Fang MC, Abe-Jones Y, Calfee CS, Matthay MA, Kangelaris KN. PMID: 31939788; PMCID: PMC7494056.
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    205. Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1). Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475; PMCID: PMC7359873.
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    208. Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020 01 01; 201(1):47-56. Jones TK, Feng R, Kerchberger VE, Reilly JP, Anderson BJ, Shashaty MGS, Wang F, Dunn TG, Riley TR, Abbott J, Ittner CAG, Christiani DC, Mikacenic C, Wurfel MM, Ware LB, Calfee CS, Matthay MA, Christie JD, Meyer NJ. PMID: 31487195; PMCID: PMC6938154.
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    209. Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study. Crit Care. 2019 12 09; 23(1):400. Anderson BJ, Calfee CS, Liu KD, Reilly JP, Kangelaris KN, Shashaty MGS, Lazaar AL, Bayliffe AI, Gallop RJ, Miano TA, Dunn TG, Johansson E, Abbott J, Jauregui A, Deiss T, Vessel K, Belzer A, Zhuo H, Matthay MA, Meyer NJ, Christie JD. PMID: 31818332; PMCID: PMC6902425.
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    210. The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury. PLoS One. 2019; 14(11):e0225601. Kwong YD, Chen S, Bouajram R, Li F, Matthay MA, Mehta KM, Glidden DV, Liu KD. PMID: 31770424; PMCID: PMC6879155.
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    211. Therapeutic Effects of Hyaluronic Acid in Bacterial Pneumonia in Ex Vivo Perfused Human Lungs. Am J Respir Crit Care Med. 2019 11 15; 200(10):1234-1245. Liu A, Park JH, Zhang X, Sugita S, Naito Y, Lee JH, Kato H, Hao Q, Matthay MA, Lee JW. PMID: 31390880; PMCID: PMC6857490.
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    212. Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. Theranostics. 2019; 9(26):8155-8170. Zhao R, Ali G, Chang J, Komatsu S, Tsukasaki Y, Nie HG, Chang Y, Zhang M, Liu Y, Jain K, Jung BG, Samten B, Jiang D, Liang J, Ikebe M, Matthay MA, Ji HL. PMID: 31754387; PMCID: PMC6857051.
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    213. Lung inflammatory environments differentially alter mesenchymal stromal cell behavior. Am J Physiol Lung Cell Mol Physiol. 2019 12 01; 317(6):L823-L831. Abreu SC, Rolandsson Enes S, Dearborn J, Goodwin M, Coffey A, Borg ZD, Dos Santos CC, Wargo MJ, Cruz FF, Loi R, DeSarno M, Ashikaga T, Antunes MA, Rocco PRM, Liu KD, Lee JW, Matthay MA, McKenna DH, Weiss DJ. PMID: 31553626; PMCID: PMC6962599.
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    214. Clinically relevant model of pneumococcal pneumonia, ARDS, and nonpulmonary organ dysfunction in mice. Am J Physiol Lung Cell Mol Physiol. 2019 11 01; 317(5):L717-L736. Gotts JE, Bernard O, Chun L, Croze RH, Ross JT, Nesseler N, Wu X, Abbott J, Fang X, Calfee CS, Matthay MA. PMID: 31509438; PMCID: PMC6879898.
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    216. A Multicenter Study of the Causes and Consequences of Optimistic Expectations About Prognosis by Surrogate Decision-Makers in ICUs. Crit Care Med. 2019 09; 47(9):1184-1193. White DB, Carson S, Anderson W, Steingrub J, Bird G, Curtis JR, Matthay M, Peterson M, Buddadhumaruk P, Shields AM, Ernecoff N, Shotsberger K, Weissfeld L, Chang CH, Pike F, Lo B, Hough CL. PMID: 31162200; PMCID: PMC6697218.
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    217. Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome. Crit Care Med. 2019 08; 47(8):1089-1096. Rogers AJ, Guan J, Trtchounian A, Hunninghake GM, Kaimal R, Desai M, Kozikowski LA, DeSouza L, Mogan S, Liu KD, Matthay MA, Steingrub J, Wheeler A, Yoon JH, Nakahira K, Choi AM, Baron RM. PMID: 31206358; PMCID: PMC6629502.
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    218. The Continued Need for Clinical Trials in Deceased Organ Donor Management. Transplantation. 2019 07; 103(7):1298-1299. Niemann CU, Matthay MA, Ware LB. PMID: 30399123.
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    219. The ex vivo human lung: research value for translational science. JCI Insight. 2019 06 06; 4(11). Ross JT, Nesseler N, Lee JW, Ware LB, Matthay MA. PMID: 31167972; PMCID: PMC6629111.
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    220. Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction. Respir Care. 2019 Sep; 64(9):1101-1108. Papolos AI, Schiller NB, Belzer A, Zhuo H, Gotts JE, Bibby D, Calfee CS, Matthay MA. PMID: 31138736.
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    221. Pathogenesis of Acute Respiratory Distress Syndrome. Semin Respir Crit Care Med. 2019 02; 40(1):31-39. Huppert LA, Matthay MA, Ware LB. PMID: 31060086; PMCID: PMC7060969.
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    222. Clinician-Family Communication About Patients' Values and Preferences in Intensive Care Units. JAMA Intern Med. 2019 05 01; 179(5):676-684. Scheunemann LP, Ernecoff NC, Buddadhumaruk P, Carson SS, Hough CL, Curtis JR, Anderson WG, Steingrub J, Lo B, Matthay M, Arnold RM, White DB. PMID: 30933293; PMCID: PMC6503570.
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    223. Is a Part Better than the Whole for Cell-based Therapy for Acute Respiratory Distress Syndrome? Anesthesiology. 2019 May; 130(5):683-685. Lee JW, Matthay MA. PMID: 30870157; PMCID: PMC6799989.
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    224. A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome. Crit Care. 2019 04 17; 23(1):128. Flori H, Sapru A, Quasney MW, Gildengorin G, Curley MAQ, Matthay MA, Dahmer MK, BALI and RESTORE Study Investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) . PMID: 30995942; PMCID: PMC6471952.
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    225. Precision medicine for cell therapy in acute respiratory distress syndrome - Authors' reply. Lancet Respir Med. 2019 04; 7(4):e14. Matthay MA, Zhuo H, Gotts JE, Liu KD, Calfee CS. PMID: 30926051.
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    228. Could Decisions to Limit Treatment Contribute to Mortality Differences between Patients with Different Presepsis Trajectories? Ann Am Thorac Soc. 2019 04; 16(4):522. Block BL, Matthay M. PMID: 30495973; PMCID: PMC6441695.
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    229. Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury. Pediatr Crit Care Med. 2019 04; 20(4):323-331. Zinter MS, Spicer AC, Liu KD, Orwoll BE, Alkhouli MF, Brakeman PR, Calfee CS, Matthay MA, Sapru A. PMID: 30672838; PMCID: PMC6454886.
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    230. Identification of Acute Kidney Injury Subphenotypes with Differing Molecular Signatures and Responses to Vasopressin Therapy. Am J Respir Crit Care Med. 2019 04 01; 199(7):863-872. Bhatraju PK, Zelnick LR, Herting J, Katz R, Mikacenic C, Kosamo S, Morrell ED, Robinson-Cohen C, Calfee CS, Christie JD, Liu KD, Matthay MA, Hahn WO, Dmyterko V, Slivinski NSJ, Russell JA, Walley KR, Christiani DC, Liles WC, Himmelfarb J, Wurfel MM. PMID: 30334632; PMCID: PMC6444649.
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    231. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019 03 14; 5(1):18. Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS. PMID: 30872586; PMCID: PMC6709677.
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    233. Prospective Assessment of the Feasibility of a Trial of Low-Tidal Volume Ventilation for Patients with Acute Respiratory Failure. Ann Am Thorac Soc. 2019 03; 16(3):356-362. Lanspa MJ, Gong MN, Schoenfeld DA, Lee KT, Grissom CK, Hou PC, Serpa-Neto A, Brown SM, Iwashyna TJ, Yealy DM, Hough CL, Brower RG, Calfee CS, Hyzy RC, Matthay MA, Miller RR, Steingrub JS, Thompson BT, Miller CD, Clemmer TP, Hendey GW, Huang DT, Mathews KS, Qadir N, Tidswell M, The National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury (P. PMID: 30407869; PMCID: PMC6394119.
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    237. ECMO in severe acute respiratory distress syndrome. Lancet Respir Med. 2019 02; 7(2):106-108. Matthay MA. PMID: 30642777; PMCID: PMC7129337.
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    238. Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma. Am J Respir Crit Care Med. 2019 01 01; 199(1):62-70. Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB. PMID: 30067389; PMCID: PMC6353017.
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    240. Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults. Proc Natl Acad Sci U S A. 2018 12 26; 115(52):E12353-E12362. Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. PMID: 30482864; PMCID: PMC6310811.
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    243. Therapeutic potential of mesenchymal stromal cells in the treatment of ARDS. Transfusion. 2019 02; 59(S1):869-875. Huppert LA, Liu KD, Matthay MA. PMID: 30383290.
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    244. Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis. Intensive Care Med. 2018 Nov; 44(11):1849-1858. Reilly JP, Wang F, Jones TK, Palakshappa JA, Anderson BJ, Shashaty MGS, Dunn TG, Johansson ED, Riley TR, Lim B, Abbott J, Ittner CAG, Cantu E, Lin X, Mikacenic C, Wurfel MM, Christiani DC, Calfee CS, Matthay MA, Christie JD, Feng R, Meyer NJ. PMID: 30343317; PMCID: PMC6697901.
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    245. Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study. Intensive Care Med. 2018 Nov; 44(11):1859-1869. Sinha P, Delucchi KL, Thompson BT, McAuley DF, Matthay MA, Calfee CS, NHLBI ARDS Network. PMID: 30291376; PMCID: PMC6317524.
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    246. Interleukin-1 Receptor Antagonist Is Associated With Pediatric Acute Respiratory Distress Syndrome and Worse Outcomes in Children With Acute Respiratory Failure. Pediatr Crit Care Med. 2018 10; 19(10):930-938. Dahmer MK, Quasney MW, Sapru A, Gildengorin G, Curley MAQ, Matthay MA, Flori H, BALI and RESTORE Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALIS. PMID: 30095747; PMCID: PMC6170680.
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    247. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. N Engl J Med. 2018 08 30; 379(9):884-887. Mi MY, Matthay MA, Morris AH. PMID: 30157406.
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    248. Assessment of industry data on pulmonary and immunosuppressive effects of IQOS. Tob Control. 2018 11; 27(Suppl 1):s20-s25. Moazed F, Chun L, Matthay MA, Calfee CS, Gotts J. PMID: 30158203; PMCID: PMC6252496.
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    249. Possible hepatotoxicity of IQOS. Tob Control. 2018 11; 27(Suppl 1):s39-s40. Chun L, Moazed F, Matthay M, Calfee C, Gotts J. PMID: 30131373; PMCID: PMC6238953.
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    250. Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury. Front Immunol. 2018; 9:1898. Liu C, Ma Y, Su Z, Zhao R, Zhao X, Nie HG, Xu P, Zhu L, Zhang M, Li X, Zhang X, Matthay MA, Ji HL. PMID: 30177934; PMCID: PMC6110197.
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    251. Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia. Thorax. 2019 01; 74(1):43-50. Park J, Kim S, Lim H, Liu A, Hu S, Lee J, Zhuo H, Hao Q, Matthay MA, Lee JW. PMID: 30076187; PMCID: PMC6295323.
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    252. Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. Lancet Respir Med. 2018 09; 6(9):691-698. Calfee CS, Delucchi KL, Sinha P, Matthay MA, Hackett J, Shankar-Hari M, McDowell C, Laffey JG, O'Kane CM, McAuley DF, Irish Critical Care Trials Group. PMID: 30078618; PMCID: PMC6201750.
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    253. Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome. Can J Kidney Health Dis. 2018; 5:2054358118789158. Hsu RK, Truwit JD, Matthay MA, Levitt JE, Thompson BT, Liu KD. PMID: 30116543; PMCID: PMC6088470.
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    255. Pulmonary mechanics and gas exchange characteristics in uncommon etiologies of acute respiratory distress syndrome. J Thorac Dis. 2018 Aug; 10(8):5030-5038. Kallet RH, Ho K, Lipnick MS, Matthay MA. PMID: 30233877; PMCID: PMC6129894.
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    257. Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L638-L644. Leligdowicz A, Chun LF, Jauregui A, Vessel K, Liu KD, Calfee CS, Matthay MA. PMID: 30024307; PMCID: PMC6295506.
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    258. Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018 10 01; 128(10):4343-4358. Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. PMID: 29999500; PMCID: PMC6159975.
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    259. Influence of Clinical Factors and Exclusion Criteria on Mortality in ARDS Observational Studies and Randomized Controlled Trials. Respir Care. 2018 08; 63(8):1060-1069. Pais FM, Sinha P, Liu KD, Matthay MA. PMID: 29991643.
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    260. A psychometric study of the decisional conflict scale in surrogate decision makers. Patient Educ Couns. 2018 11; 101(11):1957-1965. Pecanac KE, Brown RL, Steingrub J, Anderson W, Matthay MA, White DB. PMID: 30054105; PMCID: PMC6179906.
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    261. Secondary peritonitis: principles of diagnosis and intervention. BMJ. 2018 06 18; 361:k1407. Ross JT, Matthay MA, Harris HW. PMID: 29914871; PMCID: PMC6889898.
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    262. Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS. Thorax. 2018 09; 73(9):840-846. Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, Rice TW, Matthay MA, Calfee CS, Ware LB. PMID: 29903755; PMCID: PMC6410734.
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    263. Mesenchymal stromal cells and macrophages in sepsis: new insights. Eur Respir J. 2018 04; 51(4). Kotas ME, Matthay MA. PMID: 29700107.
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    264. Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload. Crit Care Med. 2018 04; 46(4):577-585. Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Michalkiewicz M, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL, National Heart, Lung, and Blood Institute (NHLBI) Recipient Epidemiology and Donor Evaluation Study-. PMID: 29300236; PMCID: PMC5851817.
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    265. Endothelial biomarkers in human sepsis: pathogenesis and prognosis for ARDS. Pulm Circ. 2018 Apr-Jun; 8(2):2045894018769876. Hendrickson CM, Matthay MA. PMID: 29575977; PMCID: PMC5912282.
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    267. Inhibiting Bruton's tyrosine kinase rescues mice from lethal influenza-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2018 07 01; 315(1):L52-L58. Florence JM, Krupa A, Booshehri LM, Davis SA, Matthay MA, Kurdowska AK. PMID: 29516781; PMCID: PMC6087894.
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    268. Assessing Preventable Harms in the Intensive Care Unit: Data From a Tertiary Care Academic Medical Institution. Am J Med Qual. 2018 May/Jun; 33(3):329. Sung N, Aldrich JM, Shimabukuro DW, Matthay MA, Liu KD. PMID: 29473421; PMCID: PMC5957774.
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    269. Elevated donor plasminogen activator inhibitor-1 levels and the risk of primary graft dysfunction. Clin Transplant. 2018 04; 32(4):e13210. Hamilton BCS, Dincheva GR, Zhuo H, Golden JA, Brzezinski M, Singer JP, Matthay MA, Kukreja J. PMID: 29377268; PMCID: PMC5924447.
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    270. The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia. Stem Cells. 2018 05; 36(5):796-806. Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH. PMID: 29396891; PMCID: PMC5918231.
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    271. Mesenchymal stem cell-derived extracellular vesicles attenuate pulmonary vascular permeability and lung injury induced by hemorrhagic shock and trauma. J Trauma Acute Care Surg. 2018 02; 84(2):245-256. Potter DR, Miyazawa BY, Gibb SL, Deng X, Togaratti PP, Croze RH, Srivastava AK, Trivedi A, Matthay M, Holcomb JB, Schreiber MA, Pati S. PMID: 29251710; PMCID: PMC6378956.
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    273. Exosome-based Therapy for Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2018 01 01; 197(1):10-12. Matthay MA, Abman SH. PMID: 28957642.
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    274. Rectal and Bladder Temperatures vs Forehead Core Temperatures Measured With SpotOn Monitoring System. Am J Crit Care. 2018 01; 27(1):43-50. Schell-Chaple HM, Liu KD, Matthay MA, Puntillo KA. PMID: 29292274.
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    275. Measurement of Protein Permeability and Fluid Transport of Human Alveolar Epithelial Type II Cells Under Pathological Conditions. Methods Mol Biol. 2018; 1809:121-128. Fang X, Matthay MA. PMID: 29987787.
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    276. Clinical Presentation and Outcomes among Children with Sepsis Presenting to a Public Tertiary Hospital in Tanzania. Front Pediatr. 2017; 5:278. Kortz TB, Sawe HR, Murray B, Enanoria W, Matthay MA, Reynolds T. PMID: 29312910; PMCID: PMC5743673.
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    278. ENaCs as Both Effectors and Regulators of MiRNAs in Lung Epithelial Development and Regeneration. Cell Physiol Biochem. 2017; 44(3):1120-1132. Ding Y, Zhao R, Zhao X, Matthay MA, Nie HG, Ji HL. PMID: 29179210; PMCID: PMC5884700.
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    279. Extracellular Vesicle Transfer from Mesenchymal Stromal Cells Modulates Macrophage Function in Acute Lung Injury. Basic Science and Clinical Implications. Am J Respir Crit Care Med. 2017 11 15; 196(10):1234-1236. Matthay MA. PMID: 28640648; PMCID: PMC5694833.
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    281. Cytokine Profiles of Severe Influenza Virus-Related Complications in Children. Front Immunol. 2017; 8:1423. Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA, PALISI PICFlu Investigators, Hertz T, Randolph AG. PMID: 29163498; PMCID: PMC5681736.
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    287. Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction. Front Immunol. 2017; 8:842. Czikora I, Alli AA, Sridhar S, Matthay MA, Pillich H, Hudel M, Berisha B, Gorshkov B, Romero MJ, Gonzales J, Wu G, Huo Y, Su Y, Verin AD, Fulton D, Chakraborty T, Eaton DC, Lucas R. PMID: 28785264; PMCID: PMC5519615.
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    289. Endothelial Damage During Septic Shock: Significance and Implications for Future Therapies. Chest. 2017 07; 152(1):1-3. Crouser ED, Matthay MA. PMID: 28693760.
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    290. Effects of IV Acetaminophen on Core Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults: A Randomized Controlled Trial. Crit Care Med. 2017 Jul; 45(7):1199-1207. Schell-Chaple HM, Liu KD, Matthay MA, Sessler DI, Puntillo KA. PMID: 28319467.
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    291. Lung Injury Etiology and Other Factors Influencing the Relationship Between Dead-Space Fraction and Mortality in ARDS. Respir Care. 2017 Oct; 62(10):1241-1248. Kallet RH, Zhuo H, Ho K, Lipnick MS, Gomez A, Matthay MA. PMID: 28611227.
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    293. Clinical trials in acute respiratory distress syndrome: challenges and opportunities. Lancet Respir Med. 2017 06; 5(6):524-534. Matthay MA, McAuley DF, Ware LB. PMID: 28664851.
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    294. Pulmonary toxicity of e-cigarettes. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L193-L206. Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. PMID: 28522559; PMCID: PMC5582932.
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    295. Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Respir Med. 2017 06; 5(6):484-491. McAuley DF, Cross LM, Hamid U, Gardner E, Elborn JS, Cullen KM, Dushianthan A, Grocott MP, Matthay MA, O'Kane CM. PMID: 28526233.
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    297. Understanding blood gas analysis. Intensive Care Med. 2018 01; 44(1):91-93. Gattinoni L, Pesenti A, Matthay M. PMID: 28497267.
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    299. Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome. Crit Care Med. 2017 May; 45(5):798-805. Festic E, Carr GE, Cartin-Ceba R, Hinds RF, Banner-Goodspeed V, Bansal V, Asuni AT, Talmor D, Rajagopalan G, Frank RD, Gajic O, Matthay MA, Levitt JE. PMID: 28240689; PMCID: PMC5392150.
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    302. Signals of vagal circuits engaging with AKT1 in α7 nAChR+CD11b+ cells lessen E. coli and LPS-induced acute inflammatory injury. Cell Discov. 2017; 3:17009. Zhao C, Yang X, Su EM, Huang Y, Li L, Matthay MA, Su X. PMID: 28529765; PMCID: PMC5419718.
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    304. Profiling of ARDS pulmonary edema fluid identifies a metabolically distinct subset. Am J Physiol Lung Cell Mol Physiol. 2017 05 01; 312(5):L703-L709. Rogers AJ, Contrepois K, Wu M, Zheng M, Peltz G, Ware LB, Matthay MA. PMID: 28258106; PMCID: PMC5451591.
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    305. Higher mini-BAL total protein concentration in early ARDS predicts faster resolution of lung injury measured by more ventilator-free days. Am J Physiol Lung Cell Mol Physiol. 2017 05 01; 312(5):L579-L585. Hendrickson CM, Abbott J, Zhuo H, Liu KD, Calfee CS, Matthay MA, NHLBI ARDS Network. PMID: 28213470; PMCID: PMC5451593.
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    306. Protein biomarkers associated with primary graft dysfunction following lung transplantation. Am J Physiol Lung Cell Mol Physiol. 2017 04 01; 312(4):L531-L541. Hamilton BC, Kukreja J, Ware LB, Matthay MA. PMID: 28130262; PMCID: PMC5407092.
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    307. Concise Review: Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction Following Trauma or Sepsis. Stem Cells. 2017 02; 35(2):316-324. Matthay MA, Pati S, Lee JW. PMID: 27888550.
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    308. Incidence and clinical characteristics of transfusion-associated circulatory overload using an active surveillance algorithm. Vox Sang. 2017 Jan; 112(1):56-63. Roubinian NH, Hendrickson JE, Triulzi DJ, Gottschall JL, Chowdhury D, Kor DJ, Looney MR, Matthay MA, Kleinman SH, Brambilla D, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III). PMID: 28001313; PMCID: PMC5257198.
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    309. Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death. Crit Care. 2016 11 17; 20(1):372. Bhatraju PK, Mukherjee P, Robinson-Cohen C, O'Keefe GE, Frank AJ, Christie JD, Meyer NJ, Liu KD, Matthay MA, Calfee CS, Christiani DC, Himmelfarb J, Wurfel MM. PMID: 27852290; PMCID: PMC5112626.
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    310. Clinical, Radiographic, Physiologic, and Biologic Measurements to Facilitate Personalized Medicine for ARDS. Chest. 2016 11; 150(5):989-990. Matthay MA, Beitler JR. PMID: 27832890.
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    311. Overnight Extubation in Patients With Mechanical Ventilation: Is It Harmful? JAMA Intern Med. 2016 11 01; 176(11):1660-1661. Moore PK, Matthay MA. PMID: 27599363.
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    381. Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1520-9. Shyamsundar M, McAuley DF, Ingram RJ, Gibson DS, O'Kane D, McKeown ST, Edwards A, Taggart C, Elborn JS, Calfee CS, Matthay MA, O'Kane CM. PMID: 24716610; PMCID: PMC4226011.
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    382. Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS One. 2014; 9(6):e99084. Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS. PMID: 24915147; PMCID: PMC4051692.
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    383. Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia. Thorax. 2014 Sep; 69(9):819-25. Asmussen S, Ito H, Traber DL, Lee JW, Cox RA, Hawkins HK, McAuley DF, McKenna DH, Traber LD, Zhuo H, Wilson J, Herndon DN, Prough DS, Liu KD, Matthay MA, Enkhbaatar P. PMID: 24891325; PMCID: PMC4284068.
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    386. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med. 2014 Aug; 2(8):611-20. Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA, NHLBI ARDS Network. PMID: 24853585; PMCID: PMC4154544.
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    389. Applying metabolomics to uncover novel biology in ARDS. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 01; 306(11):L957-61. Rogers AJ, Matthay MA. PMID: 24727586; PMCID: PMC4042190.
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    390. Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 01; 306(11):L975-85. Goolaerts A, Pellan-Randrianarison N, Larghero J, Vanneaux V, Uzunhan Y, Gille T, Dard N, Planès C, Matthay MA, Clerici C. PMID: 24682451; PMCID: PMC4042188.
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    391. A randomized trial of the effects of nebulized albuterol on pulmonary edema in brain-dead organ donors. Am J Transplant. 2014 Mar; 14(3):621-8. Ware LB, Landeck M, Koyama T, Zhao Z, Singer J, Kern R, Neidlinger N, Nguyen J, Johnson E, Janz DR, Bernard GR, Lee JW, Matthay MA, California Transplant Donor Network. PMID: 24730050; PMCID: PMC3986821.
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    392. Is there still a role for the lung injury score in the era of the Berlin definition ARDS? Ann Intensive Care. 2014 Feb 18; 4(1):4. Kangelaris KN, Calfee CS, May AK, Zhuo H, Matthay MA, Ware LB. PMID: 24533450; PMCID: PMC3931496.
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    395. Metabolomic derangements are associated with mortality in critically ill adult patients. PLoS One. 2014; 9(1):e87538. Rogers AJ, McGeachie M, Baron RM, Gazourian L, Haspel JA, Nakahira K, Fredenburgh LE, Hunninghake GM, Raby BA, Matthay MA, Otero RM, Fowler VG, Rivers EP, Woods CW, Kingsmore S, Langley RJ, Choi AM. PMID: 24498130; PMCID: PMC3907548.
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    396. Reperfusion pulmonary edema in children with tetralogy of Fallot, pulmonary atresia, and major aortopulmonary collateral arteries undergoing unifocalization procedures: A pilot study examining potential pathophysiologic mechanisms and clinical significance. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1560-5. Asija R, Roth SJ, Hanley FL, Peng L, Liu K, Abbott J, Zhuo H, Matthay M. PMID: 24534681.
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    397. One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med. 2014 Mar; 40(3):388-96. Wang CY, Calfee CS, Paul DW, Janz DR, May AK, Zhuo H, Bernard GR, Matthay MA, Ware LB, Kangelaris KN. PMID: 24435201; PMCID: PMC3943651.
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    398. TGF-β and lung fluid balance in ARDS. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):885-6. Frank JA, Matthay MA. PMID: 24449829; PMCID: PMC3903208.
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    399. Effect of simvastatin on physiological and biological outcomes in patients undergoing esophagectomy: a randomized placebo-controlled trial. Ann Surg. 2014 Jan; 259(1):26-31. Shyamsundar M, McAuley DF, Shields MO, MacSweeney R, Duffy MJ, Johnston JR, McGuigan J, Backman JT, Calfee CS, Matthay MM, Griffiths MJ, McDowell C, Elborn SJ, O'Kane CM. PMID: 23817506.
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    403. Cystic fibrosis epithelial cell and bacterial binding. Am J Physiol Lung Cell Mol Physiol. 2013 Dec; 305(11):L891. Engel J, Matthay M. PMID: 24310120.
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    409. Cell therapy for lung diseases. Report from an NIH-NHLBI workshop, November 13-14, 2012. Am J Respir Crit Care Med. 2013 Aug 01; 188(3):370-5. Matthay MA, Anversa P, Bhattacharya J, Burnett BK, Chapman HA, Hare JM, Hei DJ, Hoffman AM, Kourembanas S, McKenna DH, Ortiz LA, Ott HC, Tente W, Thébaud B, Trapnell BC, Weiss DJ, Yuan JX, Blaisdell CJ. PMID: 23713908; PMCID: PMC3778734.
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    410. Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*. Crit Care Med. 2013 Aug; 41(8):1929-37. Levitt JE, Calfee CS, Goldstein BA, Vojnik R, Matthay MA. PMID: 23782966; PMCID: PMC3748809.
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    411. Mesenchymal stem cells and idiopathic pulmonary fibrosis. Potential for clinical testing. Am J Respir Crit Care Med. 2013 Jul 15; 188(2):133-40. Toonkel RL, Hare JM, Matthay MA, Glassberg MK. PMID: 23306542.
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    412. Reply: idiopathic pulmonary fibrosis: a degenerative disease requiring a regenerative approach. Am J Respir Crit Care Med. 2013 Jul 15; 188(2):253-4. Glassberg MK, Hare JM, Toonkel RL, Matthay MA. PMID: 23855697; PMCID: PMC3778759.
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    413. Sugar administration is an effective adjunctive therapy in the treatment of Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 2013 Sep; 305(5):L352-63. Bucior I, Abbott J, Song Y, Matthay MA, Engel JN. PMID: 23792737; PMCID: PMC3763031.
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    420. The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases. J Clin Invest. 2013 May; 123(5):2037-48. Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A. PMID: 23543053; PMCID: PMC3635736.
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    421. Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice. J Immunol. 2013 May 01; 190(9):4717-24. Seeley EJ, Barry SS, Narala S, Matthay MA, Wolters PJ. PMID: 23543756; PMCID: PMC3973442.
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    422. Calcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy. J Clin Invest. 2013 Mar; 123(3):1015-8. Seeley EJ, Rosenberg P, Matthay MA. PMID: 23434597; PMCID: PMC3582152.
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    423. Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction--a randomised placebo-controlled trial (KARE): study protocol. Trials. 2013 Feb 18; 14:51. Cross LJ, O'Kane CM, McDowell C, Elborn JJ, Matthay MA, McAuley DF. PMID: 23419093; PMCID: PMC3620926.
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    424. Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. Mol Med. 2013 Feb 08; 18:1481-90. Su X, Feng X, Terrando N, Yan Y, Chawla A, Koch LG, Britton SL, Matthay MA, Maze M. PMID: 23296426; PMCID: PMC3576477.
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    425. Activation of the heat shock response attenuates the interleukin 1β-mediated inhibition of the amiloride-sensitive alveolar epithelial ion transport. Shock. 2013 Feb; 39(2):189-96. Howard M, Roux J, Iles KE, Miyazawa B, Christiaans S, Anjum N, Dickinson DA, Goolaerts A, Matthay MA, Pittet JF. PMID: 23324889; PMCID: PMC3663580.
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    426. Risk factors and outcomes in transfusion-associated circulatory overload. Am J Med. 2013 Apr; 126(4):357.e29-38. Murphy EL, Kwaan N, Looney MR, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson G, Matthay M, Bacchetti P, Toy P, TRALI Study Group. PMID: 23357450; PMCID: PMC3652681.
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    427. From protective ventilation to super-protective ventilation for acute respiratory distress syndrome. Intensive Care Med. 2013 May; 39(5):963-5. Schultz MJ, Juffermans NP, Matthay MA. PMID: 23306587; PMCID: PMC3628414.
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    428. Cecal ligation model of sepsis in mice: new insights. Crit Care Med. 2013 Jan; 41(1):356-7. Bastarache JA, Matthay MA. PMID: 23269150; PMCID: PMC3734801.
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    429. Hyperoxic acute lung injury. Respir Care. 2013 Jan; 58(1):123-41. Kallet RH, Matthay MA. PMID: 23271823; PMCID: PMC3915523.
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    431. IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism. FASEB J. 2013 Mar; 27(3):1095-106. Roux J, McNicholas CM, Carles M, Goolaerts A, Houseman BT, Dickinson DA, Iles KE, Ware LB, Matthay MA, Pittet JF. PMID: 23221335; PMCID: PMC3574281.
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    451. Quantifying the severity of acute lung injury using dead-space ventilation: should the lung injury score be updated? Respir Care. 2012 Mar; 57(3):477-9. Kallet RH, Alonso JA, Matthay MA. PMID: 22391272; PMCID: PMC3601047.
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    452. Comparison of chest radiograph scoring to lung weight as a quantitative index of pulmonary edema in organ donors. Clin Transplant. 2012 Sep-Oct; 26(5):665-71. Ware LB, Neyrinck A, O'Neal HR, Lee JW, Landeck M, Johnson E, Calfee CS, Matthay MA, California Transplant Donor Network. PMID: 22324977; PMCID: PMC3642873.
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    453. Anti-inflammatory effects of β2 adrenergic receptor agonists in experimental acute lung injury. FASEB J. 2012 May; 26(5):2137-44. Bosmann M, Grailer JJ, Zhu K, Matthay MA, Sarma JV, Zetoune FS, Ward PA. PMID: 22318967; PMCID: PMC3336792.
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    454. Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One. 2012; 7(1):e28268. Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H, Trauma ALI SNP Consortium (TASC) investigators. PMID: 22295056; PMCID: PMC3266233.
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    455. Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):2084-9. Lucas R, Sridhar S, Rick FG, Gorshkov B, Umapathy NS, Yang G, Oseghale A, Verin AD, Chakraborty T, Matthay MA, Zemskov EA, White R, Block NL, Schally AV. PMID: 22308467; PMCID: PMC3277580.
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    456. Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia. Thorax. 2012 Jun; 67(6):533-9. Gupta N, Krasnodembskaya A, Kapetanaki M, Mouded M, Tan X, Serikov V, Matthay MA. PMID: 22250097; PMCID: PMC3358432.
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    457. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest. 2012 May; 141(5):1160-1169. Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA, National Heart, Lung, and Blood Institute ARDS Network. PMID: 22207676; PMCID: PMC3342784.
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    458. Altered lymphatics in an ovine model of congenital heart disease with increased pulmonary blood flow. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15; 302(6):L530-40. Datar SA, Johnson EG, Oishi PE, Johengen M, Tang E, Aramburo A, Barton J, Kuo HC, Bennett S, Xoinis K, Reel B, Kalkan G, Sajti E, Osorio O, Raff GW, Matthay MA, Fineman JR. PMID: 22207591; PMCID: PMC3311527.
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    459. Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med. 2011 Dec; 39(12):2665-71. Liu KD, Thompson BT, Ancukiewicz M, Steingrub JS, Douglas IS, Matthay MA, Wright P, Peterson MW, Rock P, Hyzy RC, Anzueto A, Truwit JD, National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress S. PMID: 21785346; PMCID: PMC3220741.
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    460. A simple classification model for hospital mortality in patients with acute lung injury managed with lung protective ventilation. Crit Care Med. 2011 Dec; 39(12):2645-51. Brown LM, Calfee CS, Matthay MA, Brower RG, Thompson BT, Checkley W, National Institutes of Health Acute Respiratory Distress Syndrome Network Investigators. PMID: 21725235; PMCID: PMC3227537.
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    461. Transfusion-related acute lung injury: incidence and risk factors. Blood. 2012 Feb 16; 119(7):1757-67. Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA, TRALI Study Group. PMID: 22117051; PMCID: PMC3286351.
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    462. Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome. Crit Care. 2011; 15(5):185. Matthay MA, Kallet RH. PMID: 22067424; PMCID: PMC3334730.
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    463. Acute lung failure. Semin Respir Crit Care Med. 2011 Oct; 32(5):607-25. Mac Sweeney R, McAuley DF, Matthay MA. PMID: 21989697; PMCID: PMC3601050.
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    464. Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med. 2011 Sep 01; 184(5):561-8. National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials, Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT. PMID: 21562125; PMCID: PMC3175548.
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    465. Physiology, reductionism, and translational medicine: the right mix. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L389-90. Pitt BR, Christman JW, Gunst SJ, Matthay MA, Stevens T, Ware LB. PMID: 21856812.
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    466. Clinical review: Thinking outside the box--an iconoclastic view of current practice. Crit Care. 2011 Jul 26; 15(4):225. Singer M, Matthay MA. PMID: 21888690; PMCID: PMC3387582.
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    467. Claudin-4 levels are associated with intact alveolar fluid clearance in human lungs. Am J Pathol. 2011 Sep; 179(3):1081-7. Rokkam D, Lafemina MJ, Lee JW, Matthay MA, Frank JA. PMID: 21741940; PMCID: PMC3157178.
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    468. Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial. Ann Intensive Care. 2011 Jun 14; 1(1):20. Ware LB, Koyama T, Billheimer D, Landeck M, Johnson E, Brady S, Bernard GR, Matthay MA, California Transplant Donor Network. PMID: 21906362; PMCID: PMC3224478.
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    469. Clinical significance of elevated B-type natriuretic peptide in patients with acute lung injury with or without right ventricular dilatation: an observational cohort study. Ann Intensive Care. 2011 Jun 13; 1(1):18. Cepkova M, Kapur V, Ren X, Quinn T, Zhuo H, Foster E, Matthay MA, Liu KD. PMID: 21906356; PMCID: PMC3224453.
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    470. Concise review: Mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. Stem Cells. 2011 Jun; 29(6):913-9. Lee JW, Fang X, Krasnodembskaya A, Howard JP, Matthay MA. PMID: 21506195; PMCID: PMC3293251.
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    471. Positive fluid balance is associated with higher mortality and prolonged mechanical ventilation in pediatric patients with acute lung injury. Crit Care Res Pract. 2011; 2011:854142. Flori HR, Church G, Liu KD, Gildengorin G, Matthay MA. PMID: 21687578; PMCID: PMC3114079.
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    472. Mesenchymal stem cells and acute lung injury. Crit Care Clin. 2011 Jul; 27(3):719-33. Gotts JE, Matthay MA. PMID: 21742225; PMCID: PMC3134785.
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    473. An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol. 2011 May; 44(5):725-38. Matute-Bello G, Downey G, Moore BB, Groshong SD, Matthay MA, Slutsky AS, Kuebler WM, Acute Lung Injury in Animals Study Group. PMID: 21531958; PMCID: PMC7328339.
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    474. Con: corticosteroids are not indicated for treatment of acute lung injury from H1N1 viral pneumonia. Am J Respir Crit Care Med. 2011 May 01; 183(9):1127-8. Matthay MA, Liu KD. PMID: 21531953; PMCID: PMC3114049.
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    475. Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury. Respir Res. 2011 Apr 22; 12:52. Seeley EJ, McAuley DF, Eisner M, Miletin M, Zhuo H, Matthay MA, Kallet RH. PMID: 21513532; PMCID: PMC3105946.
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    476. Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2011 Jul; 301(1):L71-8. Marmai C, Sutherland RE, Kim KK, Dolganov GM, Fang X, Kim SS, Jiang S, Golden JA, Hoopes CW, Matthay MA, Chapman HA, Wolters PJ. PMID: 21498628; PMCID: PMC3129898.
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    477. Biomarkers in acute lung injury: insights into the pathogenesis of acute lung injury. Crit Care Clin. 2011 Apr; 27(2):355-77. Cross LJ, Matthay MA. PMID: 21440206; PMCID: PMC3073651.
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    478. Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Crit Care Med. 2011 Apr; 39(4):711-7. Calfee CS, Ware LB, Glidden DV, Eisner MD, Parsons PE, Thompson BT, Matthay MA, National Heart, Blood, and Lung Institute Acute Respiratory Distress Syndrome Network. PMID: 21283009; PMCID: PMC3260884.
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    479. Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1660-5. Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. PMID: 21471091; PMCID: PMC3136993.
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    480. Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. Crit Care. 2011; 15(2):R86. Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P, Ely EW, NIH NHLBI ARDS Network. PMID: 21385351; PMCID: PMC3219344.
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    481. Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. Inflamm Res. 2011 Jul; 60(7):619-32. Su X, Looney MR, Su HE, Lee JW, Song Y, Matthay MA. PMID: 21301926; PMCID: PMC3116128.
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    482. Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization. J Heart Lung Transplant. 2011 Feb; 30(2):211-7. Sapru A, Pawlikowska L, Liu KD, Khush KK, Ann-Baxter-Lowe L, Hayden V, Menza RL, Convery M, Poon A, Landeck M, Zaroff JG, Matthay MA, DOGMATIC Study Investigators. PMID: 20869266; PMCID: PMC3019270.
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    483. Informed consent in research to improve the number and quality of deceased donor organs. Crit Care Med. 2011 Feb; 39(2):280-3. Rey MM, Ware LB, Matthay MA, Bernard GR, McGuire AL, Caplan AL, Halpern SD. PMID: 20975549; PMCID: PMC3717371.
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    484. Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L516-25. Yamakawa N, Uchida T, Matthay MA, Makita K. PMID: 21257730; PMCID: PMC3075094.
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    485. Neuregulin-1-human epidermal receptor-2 signaling is a central regulator of pulmonary epithelial permeability and acute lung injury. J Biol Chem. 2011 Mar 25; 286(12):10660-70. Finigan JH, Faress JA, Wilkinson E, Mishra RS, Nethery DE, Wyler D, Shatat M, Ware LB, Matthay MA, Mason R, Silver RF, Kern JA. PMID: 21247898; PMCID: PMC3060517.
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    486. Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Crit Care Med. 2011 Jan; 39(1):40-5. Hsieh SJ, Ware LB, Eisner MD, Yu L, Jacob P, Havel C, Goniewicz ML, Matthay MA, Benowitz NL, Calfee CS. PMID: 20935560; PMCID: PMC3148017.
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    487. The acute respiratory distress syndrome: pathogenesis and treatment. Annu Rev Pathol. 2011; 6:147-63. Matthay MA, Zemans RL. PMID: 20936936; PMCID: PMC3108259.
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    488. Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37. Stem Cells. 2010 Dec; 28(12):2229-38. Krasnodembskaya A, Song Y, Fang X, Gupta N, Serikov V, Lee JW, Matthay MA. PMID: 20945332; PMCID: PMC3293245.
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    489. The utility of clinical predictors of acute lung injury: towards prevention and earlier recognition. Expert Rev Respir Med. 2010 Dec; 4(6):785-97. Levitt JE, Matthay MA. PMID: 21128753; PMCID: PMC3044497.
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    490. Stem cells in sepsis and acute lung injury. Crit Care Med. 2010 Dec; 38(12):2379-85. Cribbs SK, Matthay MA, Martin GS. PMID: 20838330; PMCID: PMC3677751.
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    491. Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury. Anat Rec (Hoboken). 2011 Jan; 294(1):165-72. Lee JS, Su X, Rackley C, Matthay MA, Gupta N. PMID: 21157927; PMCID: PMC3072226.
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    492. Thinking outside the box: Introduction. Crit Care Med. 2010 Oct; 38(10 Suppl):S511. Singer M, Matthay MA. PMID: 21164389.
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    493. Mesenchymal stem cells for acute lung injury: preclinical evidence. Crit Care Med. 2010 Oct; 38(10 Suppl):S569-73. Matthay MA, Goolaerts A, Howard JP, Lee JW. PMID: 21164399; PMCID: PMC3580946.
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    494. Therapeutic potential of mesenchymal stem cells for severe acute lung injury. Chest. 2010 Oct; 138(4):965-72. Matthay MA, Thompson BT, Read EJ, McKenna DH, Liu KD, Calfee CS, Lee JW. PMID: 20923800; PMCID: PMC2951759.
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    495. The influence of race on the development of acute lung injury in trauma patients. Am J Surg. 2011 Apr; 201(4):486-91. Brown LM, Kallet RH, Matthay MA, Dicker RA. PMID: 20832050; PMCID: PMC3006033.
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    496. Pathophysiology of transfusion-related acute lung injury. Curr Opin Hematol. 2010 Sep; 17(5):418-23. Looney MR, Gilliss BM, Matthay MA. PMID: 20601870.
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    497. Ratio of angiopoietin-2 to angiopoietin-1 as a predictor of mortality in acute lung injury patients. Crit Care Med. 2010 Sep; 38(9):1845-51. Ong T, McClintock DE, Kallet RH, Ware LB, Matthay MA, Liu KD. PMID: 20581666; PMCID: PMC4009623.
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    498. Assessing the quantity of pulmonary edema in critically ill children. Crit Care. 2010; 14(4):189. McAuley DF, Brown LM, Matthay MA. PMID: 20804574; PMCID: PMC2945115.
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    499. Alveolar fluid clearance is faster in women with acute lung injury compared to men. J Crit Care. 2011 Jun; 26(3):249-56. Bastarache JA, Ong T, Matthay MA, Ware LB. PMID: 20688464; PMCID: PMC2982881.
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    500. Advances and challenges in translating stem cell therapies for clinical diseases. Transl Res. 2010 Sep; 156(3):107-11. Matthay MA. PMID: 20801407.
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    501. Therapeutic strategies for severe acute lung injury. Crit Care Med. 2010 Aug; 38(8):1644-50. Diaz JV, Brower R, Calfee CS, Matthay MA. PMID: 20562704; PMCID: PMC4526259.
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    502. Acute respiratory distress syndrome after surgery: can the risk be decreased? Anesth Analg. 2010 Aug; 111(2):268-9. Matthay MA, Jayr C. PMID: 20664090.
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    503. Acute lung injury: epidemiology, pathogenesis, and treatment. J Aerosol Med Pulm Drug Deliv. 2010 Aug; 23(4):243-52. Johnson ER, Matthay MA. PMID: 20073554; PMCID: PMC3133560.
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    504. Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1. J Biol Chem. 2010 Aug 20; 285(34):26211-22. Fang X, Neyrinck AP, Matthay MA, Lee JW. PMID: 20554518; PMCID: PMC2924032.
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    505. Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock. Crit Care Med. 2010 Jun; 38(6):1436-41. Calfee CS, Thompson BT, Parsons PE, Ware LB, Matthay MA, Wong HR. PMID: 20386309; PMCID: PMC3348116.
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    506. Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials. Crit Care Med. 2010 Jun; 38(6):1450-7. Cooke CR, Erickson SE, Watkins TR, Matthay MA, Hudson LD, Rubenfeld GD. PMID: 20386308; PMCID: PMC3799957.
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    507. Update on acute lung injury and critical care medicine 2009. Am J Respir Crit Care Med. 2010 May 15; 181(10):1027-32. Matthay MA, Idell S. PMID: 20460547; PMCID: PMC3269230.
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    508. Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma. 2010 May; 68(5):1121-7. Fremont RD, Koyama T, Calfee CS, Wu W, Dossett LA, Bossert FR, Mitchell D, Wickersham N, Bernard GR, Matthay MA, May AK, Ware LB. PMID: 20038857; PMCID: PMC3347639.
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    509. Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2010 Jul; 299(1):L3-7. Collard HR, Calfee CS, Wolters PJ, Song JW, Hong SB, Brady S, Ishizaka A, Jones KD, King TE, Matthay MA, Kim DS. PMID: 20418386; PMCID: PMC2904092.
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    510. Regulated gene expression in cultured type II cells of adult human lung. Am J Physiol Lung Cell Mol Physiol. 2010 Jul; 299(1):L36-50. Ballard PL, Lee JW, Fang X, Chapin C, Allen L, Segal MR, Fischer H, Illek B, Gonzales LW, Kolla V, Matthay MA. PMID: 20382749; PMCID: PMC2904098.
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    511. Activation of the stress protein response inhibits the STAT1 signalling pathway and iNOS function in alveolar macrophages: role of Hsp90 and Hsp70. Thorax. 2010 Apr; 65(4):346-53. Howard M, Roux J, Lee H, Miyazawa B, Lee JW, Gartland B, Howard AJ, Matthay MA, Carles M, Pittet JF. PMID: 20388761; PMCID: PMC3118552.
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    512. Simulation of lung alveolar epithelial wound healing in vitro. J R Soc Interface. 2010 Aug 06; 7(49):1157-70. Kim SH, Matthay MA, Mostov K, Hunt CA. PMID: 20236957; PMCID: PMC2894878.
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    513. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5587-92. Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF. PMID: 20231457; PMCID: PMC2851770.
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    514. Clinical immunology: Culprits with evolutionary ties. Nature. 2010 Mar 04; 464(7285):41-2. Calfee CS, Matthay MA. PMID: 20203598; PMCID: PMC2857339.
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    515. Standards and recommendations for quantitative assessment of lung structure in research. Am J Physiol Lung Cell Mol Physiol. 2010 May; 298(5):L615. Matthay MA. PMID: 20190035; PMCID: PMC2867400.
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    516. Thirty years of critical care medicine. Crit Care. 2010; 14(3):311. Vincent JL, Singer M, Marini JJ, Moreno R, Levy M, Matthay MA, Pinsky M, Rhodes A, Ferguson ND, Evans T, Annane D, Hall JB. PMID: 20550727; PMCID: PMC2911692.
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    517. Measuring the quantity of pulmonary edema in clinical lung injury. Crit Care Med. 2010 Jan; 38(1):312-4. Brown LM, Matthay MA. PMID: 20023478.
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    518. Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem. 2010 Feb 12; 285(7):4278-90. Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF. PMID: 19996317; PMCID: PMC2836032.
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    519. Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia: delivering the secretome. Am J Respir Crit Care Med. 2009 Dec 01; 180(11):1039-41. Abman SH, Matthay MA. PMID: 19923401.
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    520. Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury. J Immunol. 2010 Jan 01; 184(1):401-10. Su X, Matthay MA, Malik AB. PMID: 19949071; PMCID: PMC2877486.
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    521. Laminin gamma2 fragments are increased in the circulation of patients with early phase acute lung injury. Intensive Care Med. 2010 Mar; 36(3):479-86. Katayama M, Ishizaka A, Sakamoto M, Fujishima S, Sekiguchi K, Asano K, Betsuyaku T, Kotani T, Ware LB, Matthay MA, Hashimoto S. PMID: 19940975; PMCID: PMC2820224.
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    522. Early elevations in B-type natriuretic peptide levels are associated with poor clinical outcomes in pediatric acute lung injury. Pediatr Pulmonol. 2009 Nov; 44(11):1118-24. Reel B, Oishi PE, Hsu JH, Gildengorin G, Matthay MA, Fineman JR, Flori H. PMID: 19830720; PMCID: PMC4427345.
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    602. Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Mol Biol Cell. 2007 May; 18(5):1693-700. Yu W, Fang X, Ewald A, Wong K, Hunt CA, Werb Z, Matthay MA, Mostov K. PMID: 17332496; PMCID: PMC1855040.
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    603. Pathogenetic significance of biological markers of ventilator-associated lung injury in experimental and clinical studies. Chest. 2006 Dec; 130(6):1906-14. Frank JA, Parsons PE, Matthay MA. PMID: 17167015; PMCID: PMC2764530.
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    604. Pulmonary artery catheter and fluid management in acute lung injury and the acute respiratory distress syndrome. Clin Chest Med. 2006 Dec; 27(4):627-35; abstract ix. Heresi GA, Arroliga AC, Wiedemann HP, Weidemann HP, Matthay MA. PMID: 17085251.
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    605. Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts. Am J Respir Cell Mol Biol. 2007 Apr; 36(4):480-90. Ning W, Dong Y, Sun J, Li C, Matthay MA, Feghali-Bostwick CA, Choi AM. PMID: 17099140; PMCID: PMC1899323.
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    606. Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation. Am J Respir Cell Mol Biol. 2007 Apr; 36(4):497-503. Wang L, Bastarache JA, Wickersham N, Fang X, Matthay MA, Ware LB. PMID: 17099142; PMCID: PMC1899324.
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    607. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med. 2006 Nov; 12(11):1286-93. Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA. PMID: 17086189; PMCID: PMC2768268.
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    608. Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. Am J Respir Crit Care Med. 2007 Feb 01; 175(3):256-62. McClintock DE, Ware LB, Eisner MD, Wickersham N, Thompson BT, Matthay MA, National Heart, Lung, and Blood Institute ARDS Network. PMID: 17082495; PMCID: PMC1899263.
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    609. Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function. Am J Respir Cell Mol Biol. 2007 Mar; 36(3):377-86. Su G, Hodnett M, Wu N, Atakilit A, Kosinski C, Godzich M, Huang XZ, Kim JK, Frank JA, Matthay MA, Sheppard D, Pittet JF. PMID: 17079779; PMCID: PMC1899321.
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    610. Protein permeability in lung injury: now in real time again? J Appl Physiol (1985). 2007 Feb; 102(2):508-9. Lee JW, Matthay MA. PMID: 17068211.
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    611. Treatment of acute lung injury: historical perspective and potential future therapies. Semin Respir Crit Care Med. 2006 Aug; 27(4):426-37. Levitt JE, Matthay MA. PMID: 16909376.
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    612. Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2006 Dec; 291(6):L1191-8. Frank JA, Wray CM, McAuley DF, Schwendener R, Matthay MA. PMID: 16877636.
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    613. Activation of the stress protein response prevents the development of pulmonary edema by inhibiting VEGF cell signaling in a model of lung ischemia-reperfusion injury in rats. FASEB J. 2006 Jul; 20(9):1519-21. Godzich M, Hodnett M, Frank JA, Su G, Pespeni M, Angel A, Howard MB, Matthay MA, Pittet JF. PMID: 16793871.
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    614. Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Med. 2006 Sep; 32(9):1293-303. Sapru A, Wiemels JL, Wiemels JL, Witte JS, Ware LB, Matthay MA. PMID: 16770611.
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    615. Sepsis and stretch: synergistic effects on alveolar epithelial cell death? Crit Care Med. 2006 Jun; 34(6):1846-7. Gupta N, Matthay MA. PMID: 16714999.
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    616. Beta-2-agonist treatment as a potential therapy for acute inhalational lung injury. Crit Care Med. 2006 Jun; 34(6):1841-2. Wiener-Kronish JP, Matthay MA. PMID: 16714996.
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    617. Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. J Clin Invest. 2006 Jun; 116(6):1615-23. Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA. PMID: 16710475; PMCID: PMC1462945.
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    618. Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest. 2006 Jun; 116(6):1606-14. Jenkins RG, Su X, Su G, Scotton CJ, Camerer E, Laurent GJ, Davis GE, Chambers RC, Matthay MA, Sheppard D. PMID: 16710477; PMCID: PMC1462943.
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    619. Higher urine desmosine levels are associated with mortality in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L566-71. McClintock DE, Starcher B, Eisner MD, Thompson BT, Hayden DL, Church GD, Matthay MA, National Heart, Lung, Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network. PMID: 16698854; PMCID: PMC2765125.
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    620. Integrating acute lung injury and regulation of alveolar fluid clearance. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L301-6. Guidot DM, Folkesson HG, Jain L, Sznajder JI, Pittet JF, Matthay MA. PMID: 16698856.
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    621. Evolving practices in critical care and potential implications for management of acute kidney injury. Clin J Am Soc Nephrol. 2006 Jul; 1(4):869-73. Liu KD, Matthay MA, Chertow GM. PMID: 17699299.
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    622. Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L354-61. Ganter MT, Ware LB, Howard M, Roux J, Gartland B, Matthay MA, Fleshner M, Pittet JF. PMID: 16679378; PMCID: PMC2765126.
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    624. Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. Am J Respir Cell Mol Biol. 2006 May; 34(5):523-6. Adler KB, Shapiro SD, Gallup M, Wu R, Randell SH, Holtzman MJ, Evans CM, Jacoby DB, Tesfaigzi Y, Rose MC, Mossman BT, Prince A, Reddy SP, Davis CW, Matthay MA. PMID: 16618787.
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    625. Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. J Intensive Care Med. 2006 May-Jun; 21(3):119-43. Cepkova M, Matthay MA. PMID: 16672636; PMCID: PMC2765330.
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    626. Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L307-11. Ware LB, Camerer E, Welty-Wolf K, Schultz MJ, Matthay MA. PMID: 16648240.
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    627. Perspectives, translational research, and letters to the editor. Am J Physiol Lung Cell Mol Physiol. 2006 Apr; 290(4):L621. Matthay MA, Christman JW, Pitt BR, Schwiebert LM, Stevens T, Ware LB. PMID: 16531563.
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    628. Alveolar epithelial ion and fluid transport: recent progress. Am J Respir Cell Mol Biol. 2006 Jul; 35(1):10-9. Folkesson HG, Matthay MA. PMID: 16514116; PMCID: PMC2658691.
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    629. Clinical trial design--effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome. J Crit Care. 2006 Mar; 21(1):23-32; discussion 32-7. Curley MA, Arnold JH, Thompson JE, Fackler JC, Grant MJ, Fineman LD, Cvijanovich N, Barr FE, Molitor-Kirsch S, Steinhorn DM, Matthay MA, Hibberd PL, Pediatric Prone Positioning Study Group. PMID: 16616620; PMCID: PMC1778462.
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    630. Stimulation of alveolar epithelial fluid clearance in human lungs by exogenous epinephrine. Crit Care Med. 2006 Mar; 34(3):676-81. Sakuma T, Gu X, Wang Z, Maeda S, Sugita M, Sagawa M, Osanai K, Toga H, Ware LB, Folkesson G, Matthay MA. PMID: 16505652; PMCID: PMC2765117.
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    631. Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Mol Cell Proteomics. 2006 Jun; 5(6):979-86. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU. PMID: 16500929.
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    632. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med. 2006 May 01; 173(9):1008-15. Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA. PMID: 16456142; PMCID: PMC2662912.
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    633. Beta-adrenergic agonist therapy as a potential treatment for acute lung injury. Am J Respir Crit Care Med. 2006 Feb 01; 173(3):254-5. Matthay MA, Abraham E. PMID: 16436367.
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    634. Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury. Crit Care. 2006; 10(5):R126. Cepkova M, Brady S, Sapru A, Matthay MA, Church G. PMID: 16956410; PMCID: PMC1751077.
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    635. Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury. Crit Care. 2006; 10(6):239. Looney MR, Matthay MA. PMID: 17169139; PMCID: PMC1794467.
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    636. Clinical practice. Acute pulmonary edema. N Engl J Med. 2005 Dec 29; 353(26):2788-96. Ware LB, Matthay MA. PMID: 16382065.
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    637. TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK. J Immunol. 2005 Dec 15; 175(12):8303-11. Han B, Mura M, Andrade CF, Okutani D, Lodyga M, dos Santos CC, Keshavjee S, Matthay M, Liu M. PMID: 16339571.
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    638. Protective effect of endogenous beta-adrenergic tone on lung fluid balance in acute bacterial pneumonia in mice. Am J Physiol Lung Cell Mol Physiol. 2006 Apr; 290(4):L769-L776. Su X, Robriquet L, Folkesson HG, Matthay MA. PMID: 16284214.
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    640. Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses. Am J Physiol Lung Cell Mol Physiol. 2006 Mar; 290(3):L478-84. Folkesson HG, Chapin CJ, Beard LL, Ertsey R, Matthay MA, Kitterman JA. PMID: 16214817.
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    641. High prevalence of pulmonary arterial thrombi in donor lungs rejected for transplantation. J Heart Lung Transplant. 2005 Oct; 24(10):1650-6. Ware LB, Fang X, Wang Y, Babcock WD, Jones K, Matthay MA. PMID: 16210143.
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    642. Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):319-27. Matthay MA, Zimmerman GA. PMID: 16172252; PMCID: PMC2715340.
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    643. Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L242-9. Fang X, Song Y, Hirsch J, Galietta LJ, Pedemonte N, Zemans RL, Dolganov G, Verkman AS, Matthay MA. PMID: 16143588.
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    644. Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanisms. J Immunol. 2005 Aug 15; 175(4):2598-605. Su X, Camerer E, Hamilton JR, Coughlin SR, Matthay MA. PMID: 16081834.
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    645. Leukotrienes in acute lung injury: a potential therapeutic target? Am J Respir Crit Care Med. 2005 Aug 01; 172(3):261-2. Frank JA, Matthay MA. PMID: 16040787; PMCID: PMC2718469.
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    646. Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA. 2005 Jul 13; 294(2):229-37. Curley MA, Hibberd PL, Fineman LD, Wypij D, Shih MC, Thompson JE, Grant MJ, Barr FE, Cvijanovich NZ, Sorce L, Luckett PM, Matthay MA, Arnold JH. PMID: 16014597; PMCID: PMC1237036.
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    647. VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema. Eur Respir J. 2005 Jul; 26(1):101-5. Ware LB, Kaner RJ, Crystal RG, Schane R, Trivedi NN, McAuley D, Matthay MA. PMID: 15994395; PMCID: PMC2757043.
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    648. Recent advances in mechanical ventilation. Am J Med. 2005 Jun; 118(6):584-91. Calfee CS, Matthay MA. PMID: 15922687.
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    649. Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells. Am J Respir Cell Mol Biol. 2005 Sep; 33(3):231-47. Suzuki T, Moraes TJ, Vachon E, Ginzberg HH, Huang TT, Matthay MA, Hollenberg MD, Marshall J, McCulloch CA, Abreu MT, Chow CW, Downey GP. PMID: 15891109; PMCID: PMC2715314.
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    650. Accuracy of physiologic dead space measurements in patients with acute respiratory distress syndrome using volumetric capnography: comparison with the metabolic monitor method. Respir Care. 2005 Apr; 50(4):462-7. Kallet RH, Daniel BM, Garcia O, Matthay MA. PMID: 15807908.
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    651. Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance. Am J Physiol Lung Cell Mol Physiol. 2005 Jul; 289(1):L104-10. Looney MR, Sartori C, Chakraborty S, James PF, Lingrel JB, Matthay MA. PMID: 15781423.
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    652. Critical care in AJRCCM 2004. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):537-44. Angus D, Ishizaka A, Matthay M, Lemaire F, Macnee W, Abraham E. PMID: 15753483.
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    653. Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway. J Biol Chem. 2005 May 13; 280(19):18579-89. Roux J, Kawakatsu H, Gartland B, Pespeni M, Sheppard D, Matthay MA, Canessa CM, Pittet JF. PMID: 15755725.
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    654. In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases. Am J Physiol Lung Cell Mol Physiol. 2005 Jun; 288(6):L1099-109. Planès C, Leyvraz C, Uchida T, Angelova MA, Vuagniaux G, Hummler E, Matthay M, Clerici C, Rossier B. PMID: 15681398.
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    655. Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med. 2005 Jan; 33(1):1-6; discussion 230-2. Parsons PE, Eisner MD, Thompson BT, Matthay MA, Ancukiewicz M, Bernard GR, Wheeler AP, NHLBI Acute Respiratory Distress Syndrome Clinical Trials Network. PMID: 15644641.
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    656. Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury. Crit Care Med. 2005 Jan; 33(1):63-70; discussion 239-40. Cheng IW, Eisner MD, Thompson BT, Ware LB, Matthay MA, Acute Respiratory Distress Syndrome Network. PMID: 15644650.
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    657. Differential effects of sustained inflation recruitment maneuvers on alveolar epithelial and lung endothelial injury. Crit Care Med. 2005 Jan; 33(1):181-8; discussion 254-5. Frank JA, McAuley DF, Gutierrez JA, Daniel BM, Dobbs L, Matthay MA. PMID: 15644667.
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    659. Is there a role for beta-adrenoceptor agonists in the management of acute lung injury and the acute respiratory distress syndrome? Treat Respir Med. 2005; 4(5):297-307. McAuley DF, Matthay MA. PMID: 16137187.
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    660. Alveolar epithelium: role in lung fluid balance and acute lung injury. Proc Am Thorac Soc. 2005; 2(3):206-13. Matthay MA, Robriquet L, Fang X. PMID: 16222039.
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    661. Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med. 2005 May 01; 171(9):995-1001. Flori HR, Glidden DV, Rutherford GW, Matthay MA. PMID: 15618461.
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    662. Integrated control of lung fluid balance. Am J Physiol Lung Cell Mol Physiol. 2004 Dec; 287(6):L1081-90. Mehta D, Bhattacharya J, Matthay MA, Malik AB. PMID: 15531757.
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    663. HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats. FASEB J. 2005 Feb; 19(2):287-9. Lee H, Pespeni M, Roux J, Dennery PA, Matthay MA, Pittet JF. PMID: 15550551.
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    664. Can nicotine treat sepsis? Nat Med. 2004 Nov; 10(11):1161-2. Matthay MA, Ware LB. PMID: 15516907.
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    665. Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2005 Mar; 288(3):L426-31. Parsons PE, Matthay MA, Ware LB, Eisner MD, National Heart, Lung, Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network. PMID: 15516488.
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    666. Acute lung injury and acute respiratory distress syndrome in pregnancy. Crit Care Clin. 2004 Oct; 20(4):577-607. Bandi VD, Munnur U, Matthay MA. PMID: 15388190.
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    667. Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice. Exp Lung Res. 2004 Sep; 30(6):479-93. Su X, Looney M, Robriquet L, Fang X, Matthay MA. PMID: 15524406.
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    668. Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndrome. Respir Care. 2004 Sep; 49(9):1008-14. Kallet RH, Alonso JA, Pittet JF, Matthay MA. PMID: 15329171.
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    669. Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock. Blood. 2004 Dec 15; 104(13):4071-9. Pugin J, Stern-Voeffray S, Daubeuf B, Matthay MA, Elson G, Dunn-Siegrist I. PMID: 15328161.
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    670. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med. 2004 Jul 22; 351(4):327-36. Brower RG, Lanken PN, MacIntyre N, Matthay MA, Morris A, Ancukiewicz M, Schoenfeld D, Thompson BT, National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. PMID: 15269312.
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    671. Hydrostatic mechanisms may contribute to the pathogenesis of human re-expansion pulmonary edema. Intensive Care Med. 2004 Oct; 30(10):1921-6. Sue RD, Matthay MA, Ware LB. PMID: 15258730.
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    672. Coagulation-dependent mechanisms and asthma. J Clin Invest. 2004 Jul; 114(1):20-3. Matthay MA, Clements JA. PMID: 15232607; PMCID: PMC437975.
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    673. Transfusion-related acute lung injury: a review. Chest. 2004 Jul; 126(1):249-58. Looney MR, Gropper MA, Matthay MA. PMID: 15249468.
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    674. Proteomics: current techniques and potential applications to lung disease. Am J Physiol Lung Cell Mol Physiol. 2004 Jul; 287(1):L1-23. Hirsch J, Hansen KC, Burlingame AL, Matthay MA. PMID: 15187006.
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    675. Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury. Crit Care Med. 2004 Jul; 32(7):1470-6. McAuley DF, Frank JA, Fang X, Matthay MA. PMID: 15241090.
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    677. Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury. Am J Respir Crit Care Med. 2004 Oct 01; 170(7):766-72. Ware LB, Eisner MD, Thompson BT, Parsons PE, Matthay MA. PMID: 15201135.
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    678. Plasma protein C levels in patients with acute lung injury: prognostic significance. Crit Care Med. 2004 May; 32(5 Suppl):S229-32. Matthay MA, Ware LB. PMID: 15118523.
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    679. H(2)O(2) inhibits alveolar epithelial wound repair in vitro by induction of apoptosis. Am J Physiol Lung Cell Mol Physiol. 2004 Aug; 287(2):L448-53. Geiser T, Ishigaki M, van Leer C, Matthay MA, Broaddus VC. PMID: 15121637.
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    680. Mechanisms of alveolar protein clearance in the intact lung. Am J Physiol Lung Cell Mol Physiol. 2004 Apr; 286(4):L679-89. Hastings RH, Folkesson HG, Matthay MA. PMID: 15003932.
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    682. Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system. Am J Physiol Lung Cell Mol Physiol. 2004 Jul; 287(1):L104-10. Fang X, Song Y, Zemans R, Hirsch J, Matthay MA. PMID: 14990396.
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    683. Malnutrition impairs alveolar fluid clearance in rat lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1268-74. Sakuma T, Zhao Y, Sugita M, Sagawa M, Toga H, Ishibashi T, Nishio M, Matthay MA. PMID: 14977628.
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    684. Pulmonary edema fluid from patients with early lung injury stimulates fibroblast proliferation through IL-1 beta-induced IL-6 expression. J Immunol. 2004 Feb 15; 172(4):2668-77. Olman MA, White KE, Ware LB, Simmons WL, Benveniste EN, Zhu S, Pugin J, Matthay MA. PMID: 14764742.
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    685. Why does acute lung injury have no impact on mortality in patients with major trauma? Crit Care Med. 2004 Feb; 32(2):583-4. McClintock DE, Matthay MA. PMID: 14758183.
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    686. Look before you leap: how do intensivists improve care for critically ill patients? Am J Med. 2004 Feb 01; 116(3):206-7. Gropper MA, Matthay MA. PMID: 14749169.
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    687. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem. 2004 Apr 09; 279(15):14871-8. Uchida T, Rossignol F, Matthay MA, Mounier R, Couette S, Clottes E, Clerici C. PMID: 14744852.
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    688. Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1095-104. Bowler RP, Duda B, Chan ED, Enghild JJ, Ware LB, Matthay MA, Duncan MW. PMID: 14742308.
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    689. Proinflammatory activity of anti-IL-8 autoantibody:IL-8 complexes in alveolar edema fluid from patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1105-13. Krupa A, Kato H, Matthay MA, Kurdowska AK. PMID: 14729508.
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    690. Acute cardiopulmonary effects of a dual-endothelin receptor antagonist on oleic acid-induced pulmonary arterial hypertension in dogs. Exp Lung Res. 2004 Jan-Feb; 30(1):31-42. Wang L, Zhu DM, Su X, Bai CX, Ware LB, Matthay MA. PMID: 14967602.
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    691. The ADP ribosyltransferase domain of Pseudomonas aeruginosa ExoT contributes to its biological activities. Infect Immun. 2004 Jan; 72(1):546-58. Garrity-Ryan L, Shafikhani S, Balachandran P, Nguyen L, Oza J, Jakobsen T, Sargent J, Fang X, Cordwell S, Matthay MA, Engel JN. PMID: 14688136; PMCID: PMC343945.
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    692. Pancreatitis-associated acute lung injury: new insights. Chest. 2003 Dec; 124(6):2341-51. Pastor CM, Matthay MA, Frossard JL. PMID: 14665518.
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    693. Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev. 2003 Dec; 14(6):523-35. Goodman RB, Pugin J, Lee JS, Matthay MA. PMID: 14563354.
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    694. Transforming growth factor-beta 1 regulates lung epithelial barrier function and fluid transport. Am J Physiol Lung Cell Mol Physiol. 2003 Dec; 285(6):L1190-1. Clerici C, Matthay MA. PMID: 14604849.
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    695. Transgenic overexpression of granulocyte macrophage-colony stimulating factor in the lung prevents hyperoxic lung injury. Am J Pathol. 2003 Dec; 163(6):2397-406. Paine R, Wilcoxen SE, Morris SB, Sartori C, Baleeiro CE, Matthay MA, Christensen PJ. PMID: 14633611; PMCID: PMC1892382.
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    696. Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury. Thorax. 2003 Nov; 58(11):983-8. Eisner MD, Parsons P, Matthay MA, Ware L, Greene K, Acute Respiratory Distress Syndrome Network. PMID: 14586055; PMCID: PMC1746524.
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    697. Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med. 2003 Nov; 31(11):2592-7. Brower RG, Morris A, MacIntyre N, Matthay MA, Hayden D, Thompson T, Clemmer T, Lanken PN, Schoenfeld D, ARDS Clinical Trials Network, National Heart, Lung, and Blood Institute, National Institutes of Heal. PMID: 14605529.
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    698. Effect of continuous hemofiltration on hemodynamics, lung inflammation and pulmonary edema in a canine model of acute lung injury. Intensive Care Med. 2003 Nov; 29(11):2034-42. Su X, Bai C, Hong Q, Zhu D, He L, Wu J, Ding F, Fang X, Matthay MA. PMID: 14557856.
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    699. Acute lung injury and the acute respiratory distress syndrome. Crit Care Clin. 2003 Oct; 19(4):693-712. Cheng IW, Matthay MA. PMID: 14601715.
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    700. Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1088-94. Ishizaka A, Matsuda T, Albertine KH, Koh H, Tasaka S, Hasegawa N, Kohno N, Kotani T, Morisaki H, Takeda J, Nakamura M, Fang X, Martin TR, Matthay MA, Hashimoto S. PMID: 12959931.
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    701. Pulmonary edema fluid antioxidants are depressed in acute lung injury. Crit Care Med. 2003 Sep; 31(9):2309-15. Bowler RP, Velsor LW, Duda B, Chan ED, Abraham E, Ware LB, Matthay MA, Day BJ. PMID: 14501961.
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    702. Transforming growth factor-beta induces fibrosis in immune cell-depleted lungs. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L522-6. Olman MA, Matthay MA. PMID: 12902316.
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    703. Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism. J Biol Chem. 2003 Nov 07; 278(45):43939-50. Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. PMID: 12930837.
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    704. Functional identification of the alveolar edema reabsorption activity of murine tumor necrosis factor-alpha. Am J Respir Crit Care Med. 2003 Nov 01; 168(9):1043-50. Elia N, Tapponnier M, Matthay MA, Hamacher J, Pache JC, Brundler MA, Totsch M, De Baetselier P, Fransen L, Fukuda N, Morel DR, Lucas R. PMID: 12842853.
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    705. Early elevation of plasma soluble intercellular adhesion molecule-1 in pediatric acute lung injury identifies patients at increased risk of death and prolonged mechanical ventilation. Pediatr Crit Care Med. 2003 Jul; 4(3):315-21. Flori HR, Ware LB, Glidden D, Matthay MA. PMID: 12831413.
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    706. Protein C and thrombomodulin in human acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L514-21. Ware LB, Fang X, Matthay MA. PMID: 12754194.
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    707. Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L20-8. Prabhakaran P, Ware LB, White KE, Cross MT, Matthay MA, Olman MA. PMID: 12730079.
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    708. Therapeutic strategies to hasten the resolution of pulmonary edema. Crit Care Med. 2003 Apr; 31(4):1288-9. Folkesson HG, Matthay MA. PMID: 12682513.
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    709. Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med. 2003 Apr 01; 167(7):1027-35. Matthay MA, Zimmerman GA, Esmon C, Bhattacharya J, Coller B, Doerschuk CM, Floros J, Gimbrone MA, Hoffman E, Hubmayr RD, Leppert M, Matalon S, Munford R, Parsons P, Slutsky AS, Tracey KJ, Ward P, Gail DB, Harabin AL. PMID: 12663342.
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    710. Prevention of ventilator-associated pneumonia: an evidence-based systematic review. Ann Intern Med. 2003 Mar 18; 138(6):494-501. Collard HR, Saint S, Matthay MA. PMID: 12639084.
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    711. Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro. Exp Cell Res. 2003 Feb 15; 283(2):215-29. Galiacy S, Planus E, Lepetit H, Féréol S, Laurent V, Ware L, Isabey D, Matthay M, Harf A, d'Ortho MP. PMID: 12581741.
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    712. High tidal volume ventilation induces NOS2 and impairs cAMP- dependent air space fluid clearance. Am J Physiol Lung Cell Mol Physiol. 2003 May; 284(5):L791-8. Frank JA, Pittet JF, Lee H, Godzich M, Matthay MA. PMID: 12562562.
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    713. Prognostic value of surfactant proteins A and D in patients with acute lung injury. Crit Care Med. 2003 Jan; 31(1):20-7. Cheng IW, Ware LB, Greene KE, Nuckton TJ, Eisner MD, Matthay MA. PMID: 12544988.
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    714. Alveolar fluid clearance in patients with ARDS: does it make a difference? Chest. 2002 Dec; 122(6 Suppl):340S-343S. Matthay MA. PMID: 12475812.
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    715. Clinical measurement of pulmonary edema. Chest. 2002 Dec; 122(6):1877-9. Matthay MA. PMID: 12475816.
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    716. Meta-analysis of acute lung injury and acute respiratory distress syndrome trials. Am J Respir Crit Care Med. 2002 Dec 01; 166(11):1515-7. Brower RG, Matthay M, Schoenfeld D. PMID: 12450936.
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    717. Lung edema clearance: 20 years of progress: invited review: alveolar edema fluid clearance in the injured lung. J Appl Physiol (1985). 2002 Dec; 93(6):2207-13. Berthiaume Y, Folkesson HG, Matthay MA. PMID: 12433940.
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    718. Alveolar epithelial fluid transport in acute lung injury: new insights. Eur Respir J. 2002 Nov; 20(5):1299-313. Sartori C, Matthay MA. PMID: 12449188.
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    719. Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2002 Nov; 283(5):L1133-42. Pham I, Uchida T, Planes C, Ware LB, Kaner R, Matthay MA, Clerici C. PMID: 12376368.
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    720. Selected contribution: mechanisms that may stimulate the resolution of alveolar edema in the transplanted human lung. J Appl Physiol (1985). 2002 Nov; 93(5):1869-74. Ware LB, Fang X, Wang Y, Sakuma T, Hall TS, Matthay MA. PMID: 12381777.
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    721. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol. 2002 Nov; 161(5):1783-96. Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB. PMID: 12414525; PMCID: PMC1850801.
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    722. Selected contribution: long-term effects of beta(2)-adrenergic receptor stimulation on alveolar fluid clearance in mice. J Appl Physiol (1985). 2002 Nov; 93(5):1875-80. Sartori C, Fang X, McGraw DW, Koch P, Snider ME, Folkesson HG, Matthay MA. PMID: 12381778.
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    723. Measuring microvascular blood flow in sepsis--a continuing challenge. Lancet. 2002 Oct 19; 360(9341):1187-8. Ware LB, Matthay MA. PMID: 12401242.
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    724. Science review: mechanisms of ventilator-induced injury. Crit Care. 2003 Jun; 7(3):233-41. Frank JA, Matthay MA. PMID: 12793874; PMCID: PMC270664.
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    725. Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells. J Biol Chem. 2002 Dec 06; 277(49):47318-24. Planès C, Blot-Chabaud M, Matthay MA, Couette S, Uchida T, Clerici C. PMID: 12372821.
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    726. Time-dependent effect of pneumonectomy on alveolar epithelial fluid clearance in rat lungs. J Thorac Cardiovasc Surg. 2002 Oct; 124(4):668-74. Sakuma T, Sagawa M, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Matthay MA. PMID: 12324723.
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    727. Invited review: Active fluid clearance from the distal air spaces of the lung. J Appl Physiol (1985). 2002 Oct; 93(4):1533-41. Matthay MA, Clerici C, Saumon G. PMID: 12235056.
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    728. Central line infections. Curr Opin Crit Care. 2002 Oct; 8(5):441-8. Lane RK, Matthay MA. PMID: 12357113.
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    729. Ventilator-induced lung injury: in vivo and in vitro mechanisms. Am J Physiol Lung Cell Mol Physiol. 2002 Oct; 283(4):L678-82. Matthay MA, Bhattacharya S, Gaver D, Ware LB, Lim LH, Syrkina O, Eyal F, Hubmayr R. PMID: 12225942.
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    730. Pleural surface fluorescence measurement of Na+ and Cl- transport across the air space-capillary barrier. J Appl Physiol (1985). 2003 Jan; 94(1):343-52. Jiang J, Song Y, Bai C, Koller BH, Matthay MA, Verkman AS. PMID: 12391048.
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    731. Assessment of lungs rejected for transplantation and implications for donor selection. Lancet. 2002 Aug 24; 360(9333):619-20. Ware LB, Wang Y, Fang X, Warnock M, Sakuma T, Hall TS, Matthay M. PMID: 12241936.
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    732. The pulmonary epithelium is an important mediator of ventilator-induced lung injury. Crit Care Med. 2002 Aug; 30(8):1910-1. Matthay MA. PMID: 12163818.
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    733. Keratinocyte growth factor can enhance alveolar epithelial repair by nonmitogenic mechanisms. Am J Physiol Lung Cell Mol Physiol. 2002 Jul; 283(1):L163-9. Atabai K, Ishigaki M, Geiser T, Ueki I, Matthay MA, Ware LB. PMID: 12060573.
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    734. Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney. J Physiol. 2002 Jul 01; 542(Pt 1):63-9. Fang X, Yang B, Matthay MA, Verkman AS. PMID: 12096051; PMCID: PMC2290384.
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    735. Lung epithelial fluid transport and the resolution of pulmonary edema. Physiol Rev. 2002 Jul; 82(3):569-600. Matthay MA, Folkesson HG, Clerici C. PMID: 12087129.
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    736. Enhancing the safety of critically ill patients by reducing urinary and central venous catheter-related infections. Am J Respir Crit Care Med. 2002 Jun 01; 165(11):1475-9. Saint S, Savel RH, Matthay MA. PMID: 12045119.
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    737. Aerosolized beta(2)-adrenergic agonists achieve therapeutic levels in the pulmonary edema fluid of ventilated patients with acute respiratory failure. Intensive Care Med. 2002 Jun; 28(6):705-11. Atabai K, Ware LB, Snider ME, Koch P, Daniel B, Nuckton TJ, Matthay MA. PMID: 12107675.
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    738. Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol. 2002 May; 282(5):L924-40. Ware LB, Matthay MA. PMID: 11943656.
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    739. Activity of pulmonary edema fluid interleukin-8 bound to alpha(2)-macroglobulin in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2002 May; 282(5):L1092-8. Kurdowska AK, Geiser TK, Alden SM, Dziadek BR, Noble JM, Nuckton TJ, Matthay MA. PMID: 11943675.
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    740. The pulmonary physician in critical care. 5: Acute lung injury and the acute respiratory distress syndrome: definitions and epidemiology. Thorax. 2002 May; 57(5):452-8. Atabai K, Matthay MA. PMID: 11978926; PMCID: PMC1746331.
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    741. Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med. 2002 Apr 25; 346(17):1281-6. Nuckton TJ, Alonso JA, Kallet RH, Daniel BM, Pittet JF, Eisner MD, Matthay MA. PMID: 11973365.
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    742. Clinical Acute Lung Injury and Acute Respiratory Distress Syndrome. Curr Treat Options Cardiovasc Med. 2002 Apr; 4(2):139-149. Matthay MA, Uchida T, Fang X. PMID: 11858776.
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    744. Distal air space epithelial fluid clearance in near-term rat fetuses is fast and requires endogenous catecholamines. Am J Physiol Lung Cell Mol Physiol. 2002 Mar; 282(3):L508-15. Folkesson HG, Matthay MA, Chapin CJ, Porta NF, Kitterman JA. PMID: 11839545.
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    745. Microarray analysis indicates that pulmonary edema fluid from patients with acute lung injury mediates inflammation, mitogen gene expression, and fibroblast proliferation through bioactive interleukin-1. Chest. 2002 Mar; 121(3 Suppl):69S-70S. Olman MA, White KE, Ware LB, Cross MT, Zhu S, Matthay MA. PMID: 11893691.
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    746. Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol. 2002 Feb; 119(2):199-207. Fang X, Fukuda N, Barbry P, Sartori C, Verkman AS, Matthay MA. PMID: 11815669; PMCID: PMC2233804.
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    747. Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats. Anesthesiology. 2002 Feb; 96(2):392-9. Laffon M, Jayr C, Barbry P, Wang Y, Folkesson HG, Pittet JF, Clerici C, Matthay MA. PMID: 11818773.
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    748. Stress preconditioning attenuates oxidative injury to the alveolar epithelium of the lung following haemorrhage in rats. J Physiol. 2002 Jan 15; 538(Pt 2):583-97. Pittet JF, Lu LN, Geiser T, Lee H, Matthay MA, Welch WJ. PMID: 11790821; PMCID: PMC2290060.
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    749. Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Am J Respir Crit Care Med. 2002 Jan 15; 165(2):242-9. Frank JA, Gutierrez JA, Jones KD, Allen L, Dobbs L, Matthay MA. PMID: 11790662.
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    750. von Willebrand factor antigen is an independent marker of poor outcome in patients with early acute lung injury. Crit Care Med. 2001 Dec; 29(12):2325-31. Ware LB, Conner ER, Matthay MA. PMID: 11801836.
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    751. Hypoxia reduces alveolar epithelial sodium and fluid transport in rats: reversal by beta-adrenergic agonist treatment. Am J Respir Cell Mol Biol. 2001 Nov; 25(5):554-61. Vivona ML, Matthay M, Chabaud MB, Friedlander G, Clerici C. PMID: 11713096.
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    752. Clinicians' approaches to mechanical ventilation in acute lung injury and ARDS. Chest. 2001 Nov; 120(5):1622-7. Thompson BT, Hayden D, Matthay MA, Brower R, Parsons PE. PMID: 11713144.
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    753. Keratinocyte growth factor reduces alveolar epithelial susceptibility to in vitro mechanical deformation. Am J Physiol Lung Cell Mol Physiol. 2001 Nov; 281(5):L1068-77. Oswari J, Matthay MA, Margulies SS. PMID: 11597897.
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    754. Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance. Am J Physiol Lung Cell Mol Physiol. 2001 Oct; 281(4):L895-903. McGraw DW, Fukuda N, James PF, Forbes SL, Woo AL, Lingrel JB, Witte DP, Matthay MA, Liggett SB. PMID: 11557593.
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    755. The Role of Protein C in Sepsis. Curr Infect Dis Rep. 2001 Oct; 3(5):413-418. Looney MR, Matthay MA. PMID: 11559461.
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    757. Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001 Jul 15; 164(2):231-6. Eisner MD, Thompson T, Hudson LD, Luce JM, Hayden D, Schoenfeld D, Matthay MA, Acute Respiratory Distress Syndrome Network. PMID: 11463593.
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    759. Beta1-adrenoceptor stimulation by high-dose terbutaline downregulates terbutaline-stimulated alveolar fluid clearance in ex vivo rat lung. Exp Lung Res. 2001 Jul-Aug; 27(5):453-68. Sakuma T, Tuchihara C, Ishigaki M, Osanai K, Nambu Y, Toga H, Takahashi K, Ohya N, Inoue M, Matthay MA. PMID: 11480585.
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    760. Partial restoration of defective chloride conductance in DeltaF508 CF mice by trimethylamine oxide. Am J Physiol Lung Cell Mol Physiol. 2001 Jul; 281(1):L52-7. Fischer H, Fukuda N, Barbry P, Illek B, Sartori C, Matthay MA. PMID: 11404245.
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    761. Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration. J Gen Physiol. 2001 Jun; 117(6):573-82. Song Y, Jayaraman S, Yang B, Matthay MA, Verkman AS. PMID: 11382807; PMCID: PMC2232398.
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    767. Pseudomonas aeruginosa ExoT inhibits in vitro lung epithelial wound repair. Cell Microbiol. 2001 Apr; 3(4):223-36. Geiser TK, Kazmierczak BI, Garrity-Ryan LK, Matthay MA, Engel JN. PMID: 11298646.
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    769. Severe sepsis--a new treatment with both anticoagulant and antiinflammatory properties. N Engl J Med. 2001 Mar 08; 344(10):759-62. Matthay MA. PMID: 11236781.
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    770. Alveolar epithelial transport. Basic science to clinical medicine. Am J Respir Crit Care Med. 2001 Mar; 163(4):1021-9. Crandall ED, Matthay MA. PMID: 11282783.
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    771. Etiology of acute pulmonary edema during liver transplantation : a series of cases with analysis of the edema fluid. Chest. 2001 Jan; 119(1):219-23. Yost CS, Matthay MA, Gropper MA. PMID: 11157607.
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    772. Transepithelial sodium and water transport in the lung. Major player and novel therapeutic target in pulmonary edema. Adv Exp Med Biol. 2001; 502:315-38. Sartori C, Matthay MA, Scherrer U. PMID: 11950147.
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    773. Increased levels of nitrate and surfactant protein a nitration in the pulmonary edema fluid of patients with acute lung injury. Am J Respir Crit Care Med. 2001 Jan; 163(1):166-72. Zhu S, Ware LB, Geiser T, Matthay MA, Matalon S. PMID: 11208643.
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    774. Denopamine, a beta(1)-adrenergic agonist, increases alveolar fluid clearance in ex vivo rat and guinea pig lungs. J Appl Physiol (1985). 2001 Jan; 90(1):10-6. Sakuma T, Tuchihara C, Ishigaki M, Osanai K, Nambu Y, Toga H, Takahashi K, Ohya N, Kurihara T, Matthay MA. PMID: 11133887.
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    775. Interleukin-1beta augments in vitro alveolar epithelial repair. Am J Physiol Lung Cell Mol Physiol. 2000 Dec; 279(6):L1184-90. Geiser T, Jarreau PH, Atabai K, Matthay MA. PMID: 11076808.
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    776. Role of aquaporin water channels in pleural fluid dynamics. Am J Physiol Cell Physiol. 2000 Dec; 279(6):C1744-50. Song Y, Yang B, Matthay MA, Ma T, Verkman AS. PMID: 11078688.
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    777. Beta-adrenergic agonist therapy accelerates the resolution of hydrostatic pulmonary edema in sheep and rats. J Appl Physiol (1985). 2000 Oct; 89(4):1255-65. Frank JA, Wang Y, Osorio O, Matthay MA. PMID: 11007557.
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    780. Diabetes mellitus: a negative predictor for the development of acute respiratory distress syndrome from septic shock. Crit Care Med. 2000 Jul; 28(7):2645-6. Frank JA, Nuckton TJ, Matthay MA. PMID: 10921610.
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    782. Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. Am J Respir Cell Mol Biol. 2000 Jun; 22(6):657-64. Kaner RJ, Ladetto JV, Singh R, Fukuda N, Matthay MA, Crystal RG. PMID: 10837361.
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    783. Cost-effectiveness of noninvasive ventilation for acute chronic obstructive pulmonary disease: cashing in too quickly. Crit Care Med. 2000 Jun; 28(6):2170-1. Jasmer RM, Matthay MA. PMID: 10890702.
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    784. Lung deflation impairs alveolar epithelial fluid transport in ischemic rabbit and rat lungs. Transplantation. 2000 May 15; 69(9):1785-93. Sakuma T, Tsukano C, Ishigaki M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Kurihara T, Nishio M, Matthay MA. PMID: 10830212.
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    785. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000 05 04; 342(18):1301-8. Acute Respiratory Distress Syndrome Network, Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A. PMID: 10793162.
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    789. Hypoxia regulates gene expression of alveolar epithelial transport proteins. J Appl Physiol (1985). 2000 May; 88(5):1890-6. Clerici C, Matthay MA. PMID: 10797154.
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    790. Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance. Am J Respir Crit Care Med. 2000 Apr; 161(4 Pt 1):1185-90. Ordoñez CL, Shaughnessy TE, Matthay MA, Fahy JV. PMID: 10764310.
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    791. A novel alveolar type I cell-specific biochemical marker of human acute lung injury. Am J Respir Crit Care Med. 2000 Mar; 161(3 Pt 1):990-5. Newman V, Gonzalez RF, Matthay MA, Dobbs LG. PMID: 10712353.
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    792. Assessment of prognosis in patients with community-acquired pneumonia who require mechanical ventilation. Chest. 2000 Feb; 117(2):503-12. Pascual FE, Matthay MA, Bacchetti P, Wachter RM. PMID: 10669697.
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    793. Dexamethasone and thyroid hormone pretreatment upregulate alveolar epithelial fluid clearance in adult rats. J Appl Physiol (1985). 2000 Feb; 88(2):416-24. Folkesson HG, Norlin A, Wang Y, Abedinpour P, Matthay MA. PMID: 10658006.
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    794. Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem. 2000 Jan 28; 275(4):2686-92. Yang B, Fukuda N, van Hoek A, Matthay MA, Ma T, Verkman AS. PMID: 10644730.
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    795. Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method. J Gen Physiol. 2000 Jan; 115(1):17-27. Song Y, Ma T, Matthay MA, Verkman AS. PMID: 10613915; PMCID: PMC1887782.
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    796. Initial severity of metabolic acidosis predicts the development of acute lung injury in severely traumatized patients. Crit Care Med. 2000 Jan; 28(1):125-31. Eberhard LW, Morabito DJ, Matthay MA, Mackersie RC, Campbell AR, Marks JD, Alonso JA, Pittet JF. PMID: 10667511.
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    797. Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med. 2000 Jan; 28(1):232-5. Abraham E, Matthay MA, Dinarello CA, Vincent JL, Cohen J, Opal SM, Glauser M, Parsons P, Fisher CJ, Repine JE. PMID: 10667529.
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    798. Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest. 2000 Jan; 105(1):93-100. Ma T, Fukuda N, Song Y, Matthay MA, Verkman AS. PMID: 10619865; PMCID: PMC382590.
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    799. Noninvasive ventilation for acute respiratory failure. J Clin Monit Comput. 2000; 16(5-6):403-8. Jasmer RM, Matthay MA. PMID: 12580223.
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    800. Early expression of beta- and gamma-subunits of epithelial sodium channel during human airway development. Am J Physiol Lung Cell Mol Physiol. 2000 Jan; 278(1):L177-84. Gaillard D, Hinnrasky J, Coscoy S, Hofman P, Matthay MA, Puchelle E, Barbry P. PMID: 10645905.
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    801. Health-related quality of life after acute lung injury. Crit Care Med. 1999 Dec; 27(12):2825-6. Eisner MD, Matthay MA. PMID: 10628634.
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    802. Exacerbation of acute pulmonary edema during assisted mechanical ventilation using a low-tidal volume, lung-protective ventilator strategy. Chest. 1999 Dec; 116(6):1826-32. Kallet RH, Alonso JA, Luce JM, Matthay MA. PMID: 10593817.
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    803. Interleukin-8 mediates injury from smoke inhalation to both the lung endothelial and the alveolar epithelial barriers in rabbits. Am J Respir Crit Care Med. 1999 Nov; 160(5 Pt 1):1443-9. Laffon M, Pittet JF, Modelska K, Matthay MA, Young DM. PMID: 10556103.
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    804. Acid-induced lung injury. Protective effect of anti-interleukin-8 pretreatment on alveolar epithelial barrier function in rabbits. Am J Respir Crit Care Med. 1999 Nov; 160(5 Pt 1):1450-6. Modelska K, Pittet JF, Folkesson HG, Courtney Broaddus V, Matthay MA. PMID: 10556104.
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    805. Interobserver variability in applying a radiographic definition for ARDS. Chest. 1999 Nov; 116(5):1347-53. Rubenfeld GD, Caldwell E, Granton J, Hudson LD, Matthay MA. PMID: 10559098.
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    806. Alveolar epithelial fluid transport can be simultaneously upregulated by both KGF and beta-agonist therapy. J Appl Physiol (1985). 1999 Nov; 87(5):1852-60. Wang Y, Folkesson HG, Jayr C, Ware LB, Matthay MA. PMID: 10562630.
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    807. alpha-adrenergic blockade restores normal fluid transport capacity of alveolar epithelium after hemorrhagic shock. Am J Physiol. 1999 10; 277(4):L760-8. Laffon M, Lu LN, Modelska K, Matthay MA, Pittet JF. PMID: 10516217.
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    808. Alveolar epithelial fluid transport and the resolution of clinically severe hydrostatic pulmonary edema. J Appl Physiol (1985). 1999 Oct; 87(4):1301-12. Verghese GM, Ware LB, Matthay BA, Matthay MA. PMID: 10517756.
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    809. The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages. Eur J Immunol. 1999 10; 29(10):3105-11. Hribar M, Bloc A, van der Goot FG, Fransen L, De Baetselier P, Grau GE, Bluethmann H, Matthay MA, Dunant Y, Pugin J, Lucas R. PMID: 10540321.
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    810. Indomethacin does not influence alveolar liquid clearance in anesthetized sheep or rats. Exp Lung Res. 1999 Sep; 25(6):517-30. Berthiaume Y, Folkesson HG, Matthay MA. PMID: 10533677.
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    811. Oxidant-mediated lung injury in the acute respiratory distress syndrome. Crit Care Med. 1999 Sep; 27(9):2028-30. Matthay MA, Geiser T, Matalon S, Ischiropoulos H. PMID: 10507639.
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    812. Acute pulmonary edema after lung transplantation: the pulmonary reimplantation response. Chest. 1999 Jul; 116(1):187-94. Khan SU, Salloum J, O'Donovan PB, Mascha EJ, Mehta AC, Matthay MA, Arroliga AC. PMID: 10424524.
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    813. HTI56, an integral apical membrane protein of the human alveolar type I cell, is a biochemical marker of acute lung injury. Chest. 1999 Jul; 116(1 Suppl):35S-36S. Newman V, Gonzalez R, Matthay M, Dobbs L. PMID: 10424584.
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    814. Elevated pulmonary edema fluid concentrations of soluble intercellular adhesion molecule-1 in patients with acute lung injury: biological and clinical significance. Chest. 1999 Jul; 116(1 Suppl):83S-84S. Conner ER, Ware LB, Modin G, Matthay MA. PMID: 10424604.
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    815. Alveolar epithelial fluid transport can be upregulated simultaneously in rats by two different mechanisms. Chest. 1999 Jul; 116(1 Suppl):98S-100S. Wang Y, Jayr C, Folkesson HG, Matthay MA. PMID: 10424619.
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    816. Conference summary: acute lung injury. Chest. 1999 Jul; 116(1 Suppl):119S-126S. Matthay MA. PMID: 10424631.
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    817. Inhibition of beta-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock. Am J Physiol. 1999 05; 276(5):L844-57. Modelska K, Matthay MA, Brown LA, Deutch E, Lu LN, Pittet JF. PMID: 10330041.
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    818. Alveolar epithelial fluid transport capacity in reperfusion lung injury after lung transplantation. Am J Respir Crit Care Med. 1999 Mar; 159(3):980-8. Ware LB, Golden JA, Finkbeiner WE, Matthay MA. PMID: 10051282.
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    819. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell. 1999 Feb 05; 96(3):319-28. Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, Pittet JF, Kaminski N, Garat C, Matthay MA, Rifkin DB, Sheppard D. PMID: 10025398.
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    820. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med. 1999 Feb; 27(2):304-12. Pugin J, Verghese G, Widmer MC, Matthay MA. PMID: 10075054.
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    821. Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. J Clin Invest. 1999 Feb; 103(4):555-61. Bai C, Fukuda N, Song Y, Ma T, Matthay MA, Verkman AS. PMID: 10021464; PMCID: PMC408096.
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    822. Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice. Am J Physiol. 1999 01; 276(1):C76-81. Yang B, Folkesson HG, Yang J, Matthay MA, Ma T, Verkman AS. PMID: 9886922.
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    823. Alveolar epithelial fluid clearance persists in the presence of moderate left atrial hypertension in sheep. J Appl Physiol (1985). 1999 Jan; 86(1):139-51. Campbell AR, Folkesson HG, Berthiaume Y, Gutkowska J, Suzuki S, Matthay MA. PMID: 9887124.
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    824. Ischemia-reperfusion lung injury in rabbits: mechanisms of injury and protection. Am J Physiol. 1999 01; 276(1):L137-45. Sakuma T, Takahashi K, Ohya N, Kajikawa O, Martin TR, Albertine KH, Matthay MA. PMID: 9887066.
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    825. Role of collagenase in mediating in vitro alveolar epithelial wound repair. J Cell Sci. 1999 Jan; 112 ( Pt 2):243-52. Planus E, Galiacy S, Matthay M, Laurent V, Gavrilovic J, Murphy G, Clérici C, Isabey D, Lafuma C, d'Ortho MP. PMID: 9858477.
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    826. Risk reduction in the intensive care unit. Am J Med. 1998 Dec; 105(6):515-23. Saint S, Matthay MA. PMID: 9870839.
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    827. Alveolar epithelial fluid transport: basic mechanisms and clinical relevance. Proc Assoc Am Physicians. 1998 Nov-Dec; 110(6):496-505. Matthay MA, Flori HR, Conner ER, Ware LB. PMID: 9824532.
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    828. Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery. Am J Obstet Gynecol. 1998 Oct; 179(4):925-33. DiFederico EM, Burlingame JM, Kilpatrick SJ, Harrison M, Matthay MA. PMID: 9790372.
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    829. Upregulation of alveolar epithelial fluid transport after subacute lung injury in rats from bleomycin. Am J Physiol. 1998 09; 275(3):L478-90. Folkesson HG, Nitenberg G, Oliver BL, Jayr C, Albertine KH, Matthay MA. PMID: 9728042.
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    830. Hepatocyte growth factor and keratinocyte growth factor in the pulmonary edema fluid of patients with acute lung injury. Biologic and clinical significance. Am J Respir Crit Care Med. 1998 Aug; 158(2):386-94. Verghese GM, McCormick-Shannon K, Mason RJ, Matthay MA. PMID: 9700111.
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    831. Protective ventilation for the acute respiratory distress syndrome. N Engl J Med. 1998 Jul 16; 339(3):197; author reply 198-9. Parsons PE, Matthay M. PMID: 9669913.
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    832. A mouse model to test the in vivo efficacy of chemical chaperones. J Pharmacol Toxicol Methods. 1998 Jul; 40(1):39-45. Bai C, Biwersi J, Verkman AS, Matthay MA. PMID: 9920533.
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    833. Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels. Am J Respir Cell Mol Biol. 1998 Jul; 19(1):143-9. Ma T, Yang B, Matthay MA, Verkman AS. PMID: 9651190.
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    834. Effects of ATP-sensitive potassium channel opener on potassium transport and alveolar fluid clearance in the resected human lung. Pharmacol Toxicol. 1998 Jul; 83(1):16-22. Sakuma T, Takahashi K, Ohya N, Nakada T, Matthay MA. PMID: 9764421.
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    835. New in situ mouse model to quantify alveolar epithelial fluid clearance. J Appl Physiol (1985). 1998 May; 84(5):1763-7. Garat C, Carter EP, Matthay MA. PMID: 9572828.
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    836. The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med. 1998 Apr; 157(4 Pt 1):1332-47. Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM. PMID: 9563759.
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    837. High microvascular endothelial water permeability in mouse lung measured by a pleural surface fluorescence method. Biophys J. 1998 Apr; 74(4):2121-8. Carter EP, Olveczky BP, Matthay MA, Verkman AS. PMID: 9545071; PMCID: PMC1299553.
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    838. The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling. Intensive Care Med. 1998 Apr; 24(4):378-98. Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM. PMID: 9609420.
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    839. Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2991-6. Dobbs LG, Gonzalez R, Matthay MA, Carter EP, Allen L, Verkman AS. PMID: 9501203; PMCID: PMC19682.
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    840. Just say NO to inhaled nitric oxide for the acute respiratory distress syndrome. Crit Care Med. 1998 Jan; 26(1):1-2. Matthay MA, Pittet JF, Jayr C. PMID: 9428528.
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    841. Developmental changes in water permeability across the alveolar barrier in perinatal rabbit lung. J Clin Invest. 1997 Sep 01; 100(5):1071-8. Carter EP, Umenishi F, Matthay MA, Verkman AS. PMID: 9276723; PMCID: PMC508281.
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    842. Early detection of type III procollagen peptide in acute lung injury. Pathogenetic and prognostic significance. Am J Respir Crit Care Med. 1997 Sep; 156(3 Pt 1):840-5. Chesnutt AN, Matthay MA, Tibayan FA, Clark JG. PMID: 9310002.
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    843. Upregulation of alveolar liquid clearance after fluid resuscitation for hemorrhagic shock in rats. Am J Physiol. 1997 Aug; 273(2 Pt 1):L305-14. Modelska K, Matthay MA, McElroy MC, Pittet JF. PMID: 9277441.
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    844. Dobutamine increases alveolar liquid clearance in ventilated rats by beta-2 receptor stimulation. Am J Respir Crit Care Med. 1997 Aug; 156(2 Pt 1):438-44. Tibayan FA, Chesnutt AN, Folkesson HG, Eandi J, Matthay MA. PMID: 9279221.
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    845. Noninvasive positive pressure ventilation for acute respiratory failure: underutilized or overrated? Chest. 1997 Jun; 111(6):1672-8. Jasmer RM, Luce JM, Matthay MA. PMID: 9187192.
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    846. Inhibition of CD18 or CD11b attenuates acute lung injury after acid instillation in rabbits. J Appl Physiol (1985). 1997 Jun; 82(6):1743-50. Folkesson HG, Matthay MA. PMID: 9173936.
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    847. Evidence for a hydrostatic mechanism in human neurogenic pulmonary edema. Chest. 1997 May; 111(5):1326-33. Smith WS, Matthay MA. PMID: 9149590.
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    848. Alveolar epithelial fluid clearance mechanisms are intact after moderate hyperoxic lung injury in rats. Chest. 1997 May; 111(5):1381-8. Garat C, Meignan M, Matthay MA, Luo DF, Jayr C. PMID: 9149598.
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    849. Protein tyrosine phosphatases mediate cell readhesion in alveolar epithelial cells mechanically separated from in vitro matrix. Am J Respir Cell Mol Biol. 1997 May; 16(5):613-20. Oliver BL, Garat C, Pytela R, Matthay MA. PMID: 9160844.
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    850. Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med. 1997 Apr; 155(4):1187-205. Pittet JF, Mackersie RC, Martin TR, Matthay MA. PMID: 9105054.
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    851. Soluble transforming growth factor-alpha is present in the pulmonary edema fluid of patients with acute lung injury. Chest. 1997 Mar; 111(3):652-6. Chesnutt AN, Kheradmand F, Folkesson HG, Alberts M, Matthay MA. PMID: 9118703.
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    852. Beta-adrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs. Am J Respir Crit Care Med. 1997 Feb; 155(2):506-12. Sakuma T, Folkesson HG, Suzuki S, Okaniwa G, Fujimura S, Matthay MA. PMID: 9032186.
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    853. Acute bacterial pneumonia in rats increases alveolar epithelial fluid clearance by a tumor necrosis factor-alpha-dependent mechanism. J Clin Invest. 1997 Jan 15; 99(2):325-35. Rezaiguia S, Garat C, Delclaux C, Meignan M, Fleury J, Legrand P, Matthay MA, Jayr C. PMID: 9006001; PMCID: PMC507800.
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    854. Increased alveolar fluid clearance following thoracotomy: report of a case and results of an analysis. Surg Today. 1997; 27(8):762-5. Sakuma T, Usuda K, Handa M, Okaniwa G, Nakada T, Fujimura S, Matthay MA. PMID: 9306595.
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    855. Soluble and insoluble fibronectin increases alveolar epithelial wound healing in vitro. Am J Physiol. 1996 Nov; 271(5 Pt 1):L844-53. Garat C, Kheradmand F, Albertine KH, Folkesson HG, Matthay MA. PMID: 8944729.
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    856. Sharp increase in rat lung water channel expression in the perinatal period. Am J Respir Cell Mol Biol. 1996 Nov; 15(5):673-9. Umenishi F, Carter EP, Yang B, Oliver B, Matthay MA, Verkman AS. PMID: 8918374.
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    857. Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome. J Immunol. 1996 Sep 15; 157(6):2699-706. Kurdowska A, Miller EJ, Noble JM, Baughman RP, Matthay MA, Brelsford WG, Cohen AB. PMID: 8805676.
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    858. Increased interleukin-8 concentrations in the pulmonary edema fluid of patients with acute respiratory distress syndrome from sepsis. Crit Care Med. 1996 Sep; 24(9):1448-54. Miller EJ, Cohen AB, Matthay MA. PMID: 8797614.
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    859. Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method. J Gen Physiol. 1996 Sep; 108(3):133-42. Carter EP, Matthay MA, Farinas J, Verkman AS. PMID: 8882859; PMCID: PMC2229323.
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    860. Acid aspiration induced lung injury. New insights and therapeutic options. Am J Respir Crit Care Med. 1996 Aug; 154(2 Pt 1):277-8. Matthay MA, Rosen GD. PMID: 8756794.
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    861. Transforming growth factor-alpha increases alveolar liquid clearance in anesthetized ventilated rats. Am J Physiol. 1996 Aug; 271(2 Pt 1):L236-44. Folkesson HG, Pittet JF, Nitenberg G, Matthay MA. PMID: 8770062.
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    862. Alveolar liquid clearance is increased by endogenous catecholamines in hemorrhagic shock in rats. J Appl Physiol (1985). 1996 Aug; 81(2):830-7. Pittet JF, Brenner TJ, Modelska K, Matthay MA. PMID: 8872653.
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    863. The acute respiratory distress syndrome. N Engl J Med. 1996 May 30; 334(22):1469-70. Matthay MA. PMID: 8618587.
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    864. Alveolar epithelial clearance of protein. J Appl Physiol (1985). 1996 May; 80(5):1431-45. Folkesson HG, Matthay MA, Weström BR, Kim KJ, Karlsson BW, Hastings RH. PMID: 8727524.
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    865. Preservation of alveolar epithelial fluid transport mechanisms in rewarmed human lung after severe hypothermia. J Appl Physiol (1985). 1996 May; 80(5):1681-6. Sakuma T, Suzuki S, Usuda K, Handa M, Okaniwa G, Nakada T, Fujimura S, Matthay MA. PMID: 8727555.
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    866. Pulmonary edema in a woman following fetal surgery. Chest. 1996 Apr; 109(4):1114-7. DiFederico EM, Harrison M, Matthay MA. PMID: 8635343.
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    867. Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am J Physiol. 1996 Apr; 270(4 Pt 1):L487-503. Matthay MA, Folkesson HG, Verkman AS. PMID: 8928808.
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    868. Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport. J Clin Invest. 1996 Feb 01; 97(3):664-71. Folkesson HG, Matthay MA, Frigeri A, Verkman AS. PMID: 8609221; PMCID: PMC507102.
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    869. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med. 1996 Jan 01; 183(1):109-17. Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, Locksley RM. PMID: 8551213; PMCID: PMC2192426.
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    870. Identification of patients with acute lung injury. Predictors of mortality. Am J Respir Crit Care Med. 1995 Dec; 152(6 Pt 1):1818-24. Doyle RL, Szaflarski N, Modin GW, Wiener-Kronish JP, Matthay MA. PMID: 8520742.
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    871. Alveolar endotoxin increases alveolar liquid clearance in rats. J Appl Physiol (1985). 1995 Dec; 79(6):2021-8. Garat C, Rezaiguia S, Meignan M, D'Ortho MP, Harf A, Matthay MA, Jayr C. PMID: 8847269.
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    872. Cellular uptake of albumin from lungs of anesthetized rabbits. Am J Physiol. 1995 Oct; 269(4 Pt 1):L453-62. Hastings RH, Folkesson HG, Petersen V, Ciriales R, Matthay MA. PMID: 7485517.
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    873. Acid aspiration-induced lung injury in rabbits is mediated by interleukin-8-dependent mechanisms. J Clin Invest. 1995 Jul; 96(1):107-16. Folkesson HG, Matthay MA, Hébert CA, Broaddus VC. PMID: 7615779; PMCID: PMC185178.
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    874. Evaluation of definitions of ARDS. Am J Respir Crit Care Med. 1995 Apr; 151(4):1270-1. Rubenfeld GD, Doyle RL, Matthay MA. PMID: 7697267.
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    875. Resistance of the alveolar epithelium to injury from septic shock in sheep. Am J Respir Crit Care Med. 1995 Apr; 151(4):1093-100. Pittet JF, Wiener-Kronish JP, Serikov V, Matthay MA. PMID: 7697237.
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    876. Death and other complications of emergency airway management in critically ill adults. A prospective investigation of 297 tracheal intubations. Anesthesiology. 1995 Feb; 82(2):367-76. Schwartz DE, Matthay MA, Cohen NH. PMID: 7856895.
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    877. Frequency and importance of barotrauma in 100 patients with acute lung injury. Crit Care Med. 1995 Feb; 23(2):272-8. Schnapp LM, Chin DP, Szaflarski N, Matthay MA. PMID: 7867352.
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    878. Fibrosing alveolitis in the adult respiratory distress syndrome. Ann Intern Med. 1995 Jan 01; 122(1):65-6. Matthay MA. PMID: 7985899.
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    879. Transforming growth factor-alpha enhances alveolar epithelial cell repair in a new in vitro model. Am J Physiol. 1994 Dec; 267(6 Pt 1):L728-38. Kheradmand F, Folkesson HG, Shum L, Derynk R, Pytela R, Matthay MA. PMID: 7810677.
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    880. The effect of salt water on alveolar epithelial barrier function. Am J Respir Crit Care Med. 1994 Dec; 150(6 Pt 1):1555-63. Folkesson HG, Kheradmand F, Matthay MA. PMID: 7952614.
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    881. Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats. J Clin Invest. 1994 Aug; 94(2):663-71. Pittet JF, Wiener-Kronish JP, McElroy MC, Folkesson HG, Matthay MA. PMID: 8040320; PMCID: PMC296144.
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    882. Alveolar fluid clearance in the resected human lung. Am J Respir Crit Care Med. 1994 Aug; 150(2):305-10. Sakuma T, Okaniwa G, Nakada T, Nishimura T, Fujimura S, Matthay MA. PMID: 8049807.
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    883. Alveolar liquid and protein clearance in anesthetized ventilated rats. J Appl Physiol (1985). 1994 Jun; 76(6):2636-42. Jayr C, Garat C, Meignan M, Pittet JF, Zelter M, Matthay MA. PMID: 7928894.
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    884. Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4970-4. Folkesson HG, Matthay MA, Hasegawa H, Kheradmand F, Verkman AS. PMID: 7515184; PMCID: PMC43911.
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    885. Effect of endocytosis inhibitors on alveolar clearance of albumin, immunoglobulin G, and SP-A in rabbits. Am J Physiol. 1994 May; 266(5 Pt 1):L544-52. Hastings RH, Wright JR, Albertine KH, Ciriales R, Matthay MA. PMID: 8203547.
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    886. Function of the alveolar epithelial barrier under pathologic conditions. Chest. 1994 Mar; 105(3 Suppl):67S-74S. Matthay MA. PMID: 8131616.
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    887. Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J Biol Chem. 1994 Feb 25; 269(8):5497-500. Hasegawa H, Ma T, Skach W, Matthay MA, Verkman AS. PMID: 7509789.
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    888. Prevalence and severity of neurologic dysfunction in critically ill patients. Influence on need for continued mechanical ventilation. Chest. 1993 Dec; 104(6):1818-24. Kelly BJ, Matthay MA. PMID: 8252971.
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    889. Alveolar epithelial barrier and acute lung injury. New Horiz. 1993 Nov; 1(4):613-22. Matthay MA, Folkesson HG, Campagna A, Kheradmand F. PMID: 8087581.
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    890. Transient effect of epidermal growth factor on the motility of an immortalized mammary epithelial cell line. J Cell Sci. 1993 Nov; 106 ( Pt 3):869-78. Matthay MA, Thiery JP, Lafont F, Stampfer F, Boyer B. PMID: 8308069.
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    891. Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits. J Appl Physiol (1985). 1993 Oct; 75(4):1661-9. Wiener-Kronish JP, Sakuma T, Kudoh I, Pittet JF, Frank D, Dobbs L, Vasil ML, Matthay MA. PMID: 8282618.
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    892. Pseudomonas aeruginosa-induced lung and pleural injury in sheep. Differential protective effect of circulating versus alveolar immunoglobulin G antibody. J Clin Invest. 1993 Sep; 92(3):1221-8. Pittet JF, Matthay MA, Pier G, Grady M, Wiener-Kronish JP. PMID: 8376581; PMCID: PMC288261.
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    893. Effect of temperature on alveolar liquid and protein clearance in an in situ perfused goat lung. J Appl Physiol (1985). 1993 Aug; 75(2):940-7. Serikov VB, Grady M, Matthay MA. PMID: 8226499.
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    894. Neutrophil-activating peptide-2 in patients with pulmonary edema from congestive heart failure or ARDS. Am J Physiol. 1993 May; 264(5 Pt 1):L490-5. Cohen AB, Stevens MD, Miller EJ, Atkinson MA, Mullenbach G, Maunder RJ, Martin TR, Wiener-Kronish JP, Matthay MA. PMID: 8498526.
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    895. Preoperative and intraoperative factors associated with prolonged mechanical ventilation. A study in patients following major abdominal vascular surgery. Chest. 1993 Apr; 103(4):1231-6. Jayr C, Matthay MA, Goldstone J, Gold WM, Wiener-Kronish JP. PMID: 8131471.
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    896. Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock. J Immunol. 1993 Jan 15; 150(2):644-54. Newman W, Beall LD, Carson CW, Hunder GG, Graben N, Randhawa ZI, Gopal TV, Wiener-Kronish J, Matthay MA. PMID: 7678280.
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    897. Alveolar liquid and protein clearance in the absence of blood flow or ventilation in sheep. J Appl Physiol (1985). 1993 Jan; 74(1):176-85. Sakuma T, Pittet JF, Jayr C, Matthay MA. PMID: 7680335.
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    898. Neuropeptides in pulmonary edema fluid of adult respiratory distress syndrome. Inflammation. 1992 Oct; 16(5):509-17. Espiritu RF, Pittet JF, Matthay MA, Goetzl EJ. PMID: 1428125.
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    899. Clearance of different-sized proteins from the alveolar space in humans and rabbits. J Appl Physiol (1985). 1992 Oct; 73(4):1310-6. Hastings RH, Grady M, Sakuma T, Matthay MA. PMID: 1447074.
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    900. Pulmonary edema associated with salt water near-drowning: new insights. Am Rev Respir Dis. 1992 Sep; 146(3):794-6. Cohen DS, Matthay MA, Cogan MG, Murray JF. PMID: 1519866.
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    901. Persistent paralysis in critically ill patients after long-term administration of vecuronium. N Engl J Med. 1992 Aug 20; 327(8):524-8. Segredo V, Caldwell JE, Matthay MA, Sharma ML, Gruenke LD, Miller RD. PMID: 1353252.
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    902. Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis. 1992 Aug; 146(2):427-32. Miller EJ, Cohen AB, Nagao S, Griffith D, Maunder RJ, Martin TR, Weiner-Kronish JP, Sticherling M, Christophers E, Matthay MA. PMID: 1489135.
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    903. Obstetric patients requiring critical care. A five-year review. Chest. 1992 May; 101(5):1407-12. Kilpatrick SJ, Matthay MA. PMID: 1582306.
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    904. Effect of epinephrine on the ability of end-tidal carbon dioxide readings to predict initial resuscitation from cardiac arrest. Crit Care Med. 1992 Mar; 20(3):337-43. Callaham M, Barton C, Matthay M. PMID: 1541094.
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    905. Alveolar and lung liquid clearance in the absence of pulmonary blood flow in sheep. J Appl Physiol (1985). 1991 Nov; 71(5):1679-87. Jayr C, Matthay MA. PMID: 1761463.
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    906. Differential responses of the endothelial and epithelial barriers of the lung in sheep to Escherichia coli endotoxin. J Clin Invest. 1991 Sep; 88(3):864-75. Wiener-Kronish JP, Albertine KH, Matthay MA. PMID: 1885774; PMCID: PMC295473.
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    907. Critical care medicine. JAMA. 1991 Jun 19; 265(23):3109-11. Matthay MA, Matthay RA. PMID: 2041115.
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    908. Alveolar and lung liquid clearance in anesthetized rabbits. J Appl Physiol (1985). 1991 Apr; 70(4):1827-35. Smedira N, Gates L, Hastings R, Jayr C, Sakuma T, Pittet JF, Matthay MA. PMID: 2055861.
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    909. Resolution of pulmonary edema. New insights. West J Med. 1991 Mar; 154(3):315-21. Matthay MA. PMID: 2028590; PMCID: PMC1002752.
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    910. Right-heart catheterization is a diagnostic procedure not a therapeutic intervention. J Intensive Care Med. 1991 Mar-Apr; 6(2):101-4. Chatterjee K, Matthay M. PMID: 10147954.
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    911. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis. 1990 Dec; 142(6 Pt 1):1250-7. Matthay MA, Wiener-Kronish JP. PMID: 2252240.
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    912. The adult respiratory distress syndrome. Definition and prognosis. Clin Chest Med. 1990 Dec; 11(4):575-80. Matthay MA. PMID: 2268989.
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    913. Pulmonary endothelial cell injury and altered lung metabolic function. Early detection of the adult respiratory distress syndrome and possible functional significance. Clin Chest Med. 1990 Dec; 11(4):723-36. Wiedemann HP, Matthay MA, Gillis CN. PMID: 2268998.
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    914. Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest. 1990 Aug; 86(2):474-80. Rubin DB, Wiener-Kronish JP, Murray JF, Green DR, Turner J, Luce JM, Montgomery AB, Marks JD, Matthay MA. PMID: 2384595; PMCID: PMC296749.
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    915. The adult respiratory distress syndrome: definition and prognosis, pathogenesis and treatment. Br J Anaesth. 1990 Jul; 65(1):107-29. Wiener-Kronish JP, Gropper MA, Matthay MA. PMID: 2200479.
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    916. Comparison of transesophageal echocardiographic and scintigraphic estimates of left ventricular end-diastolic volume index and ejection fraction in patients following coronary artery bypass grafting. Anesthesiology. 1990 Apr; 72(4):607-12. Urbanowicz JH, Shaaban MJ, Cohen NH, Cahalan MK, Botvinick EH, Chatterjee K, Schiller NB, Dae MW, Matthay MA. PMID: 2321775.
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    917. The case for oxidants in the adult respiratory distress syndrome--"elementary, Dr. Watson". J Lab Clin Med. 1990 Apr; 115(4):394-5. Heffner JE, Matthay MA. PMID: 2324608.
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    918. Prolonged neuromuscular blockade after long-term administration of vecuronium in two critically ill patients. Anesthesiology. 1990 Mar; 72(3):566-70. Segredo V, Matthay MA, Sharma ML, Gruenke LD, Caldwell JE, Miller RD. PMID: 1968730.
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    919. Pulmonary manifestations of endocrine and metabolic disorders. Clin Chest Med. 1989 Dec; 10(4):645-53. Brüssel T, Matthay MA, Chernow B. PMID: 2689069.
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    920. Protein clearance from the air spaces and lungs of unanesthetized sheep over 144 h. J Appl Physiol (1985). 1989 Nov; 67(5):1887-97. Berthiaume Y, Albertine KH, Grady M, Fick G, Matthay MA. PMID: 2600023.
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    921. Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability. J Clin Invest. 1989 Nov; 84(5):1609-19. Martin TR, Pistorese BP, Chi EY, Goodman RB, Matthay MA. PMID: 2553777; PMCID: PMC304027.
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    922. New modes of mechanical ventilation for ARDS. How should they be evaluated? Chest. 1989 Jun; 95(6):1175-7. Matthay MA. PMID: 2721246.
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    923. Ureteral obstruction caused by vasculitis. J Urol. 1989 Apr; 141(4):933-5. Baskin L, Mee S, Matthay M, Carroll PR. PMID: 2564444.
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    924. The adult respiratory distress syndrome. New insights into diagnosis, pathophysiology, and treatment. West J Med. 1989 Feb; 150(2):187-94. Matthay MA. PMID: 2658327; PMCID: PMC1026332.
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    925. Respiratory management after cardiac surgery. Chest. 1989 Feb; 95(2):424-34. Matthay MA, Wiener-Kronish JP. PMID: 2914495.
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    926. Fate of aerosolized recombinant DNA-produced alpha 1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance. Proc Natl Acad Sci U S A. 1989 Jan; 86(2):680-4. Hubbard RC, Casolaro MA, Mitchell M, Sellers SE, Arabia F, Matthay MA, Crystal RG. PMID: 2783491; PMCID: PMC286537.
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    927. Bedside catheterization of the pulmonary artery: risks compared with benefits. Ann Intern Med. 1988 Nov 15; 109(10):826-34. Matthay MA, Chatterjee K. PMID: 3056159.
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    928. Relationship of pleural effusions to increased permeability pulmonary edema in anesthetized sheep. J Clin Invest. 1988 Oct; 82(4):1422-9. Wiener-Kronish JP, Broaddus VC, Albertine KH, Gropper MA, Matthay MA, Staub NC. PMID: 3170750; PMCID: PMC442700.
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    929. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988 Sep; 138(3):720-3. Murray JF, Matthay MA, Luce JM, Flick MR. PMID: 3202424.
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    930. Alveolar liquid and protein clearance from normal dog lungs. J Appl Physiol (1985). 1988 Aug; 65(2):585-93. Berthiaume Y, Broaddus VC, Gropper MA, Tanita T, Matthay MA. PMID: 3170409.
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    931. Hydrostatic versus increased permeability pulmonary edema: diagnosis based on radiographic criteria in critically ill patients. Radiology. 1988 Jul; 168(1):73-9. Aberle DR, Wiener-Kronish JP, Webb WR, Matthay MA. PMID: 3380985.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    932. Sulfidopeptide-leukotriene peptidases in pulmonary edema fluid from patients with the adult respiratory distress syndrome. J Clin Immunol. 1988 Jul; 8(4):250-8. Ratnoff WD, Matthay MA, Wong MY, Ito Y, Vu KH, Wiener-Kronish J, Goetzl EJ. PMID: 2842367.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    933. Pleural effusions associated with hydrostatic and increased permeability pulmonary edema. Chest. 1988 Apr; 93(4):852-8. Wiener-Kronish JP, Matthay MA. PMID: 3349844.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    934. Lack of association of pleural effusion with chronic pulmonary arterial and right atrial hypertension. Chest. 1987 Dec; 92(6):967-70. Wiener-Kronish JP, Goldstein R, Matthay RA, Biondi JW, Broaddus VC, Chatterjee K, Matthay MA. PMID: 3677841.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    935. Adult respiratory distress syndrome related to antilymphocyte globulin therapy. Chest. 1987 Apr; 91(4):619-20. Dean NC, Amend WC, Matthay MA. PMID: 3549177.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    936. Beta-adrenergic agonists increase lung liquid clearance in anesthetized sheep. J Clin Invest. 1987 Feb; 79(2):335-43. Berthiaume Y, Staub NC, Matthay MA. PMID: 2879851; PMCID: PMC424066.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    937. The adult respiratory distress syndrome. Yale J Biol Med. 1986 Nov-Dec; 59(6):575-97. Biondi JW, Hines RL, Barash PG, Baker CC, Matthay MA, Matthay RA. PMID: 3538681; PMCID: PMC2590207.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    938. Helium-oxygen gas therapy. Use and availability for the emergency treatment of inoperable airway obstruction. Chest. 1986 Sep; 90(3):455-7. Curtis JL, Mahlmeister M, Fink JB, Lampe G, Matthay MA, Stulbarg MS. PMID: 3743166.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    939. Pathophysiology of the adult respiratory distress syndrome. What have we learned from human studies? Crit Care Clin. 1986 Jul; 2(3):429-53. Fein A, Wiener-Kronish JP, Niederman M, Matthay MA. PMID: 3331557.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    940. Central intravascular pressure measurements: when should we believe them? J Thorac Imaging. 1986 Jul; 1(3):52-9. Gates LM, Matthay MA. PMID: 3298681.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    941. Poor correlation between pulmonary arterial wedge pressure and left ventricular end-diastolic volume after coronary artery bypass graft surgery. Anesthesiology. 1986 Jun; 64(6):764-70. Hansen RM, Viquerat CE, Matthay MA, Wiener-Kronish JP, DeMarco T, Bahtia S, Marks JD, Botvinick EH, Chatterjee K. PMID: 3487261.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    942. Clinical spectrum of pulmonary mucormycosis. Chest. 1986 Mar; 89(3):435-9. Bigby TD, Serota ML, Tierney LM, Matthay MA. PMID: 3081299.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    943. Leukotrienes in pulmonary edema fluid after cardiopulmonary bypass. Anesth Analg. 1986 Mar; 65(3):306-8. Swerdlow BN, Mihm FG, Goetzl EJ, Matthay MA. PMID: 3006549.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    944. Pulmonary embolism. Guide to diagnosis, treatment, and prevention. Postgrad Med. 1986 Mar; 79(4):333-7, 340-3. Broaddus C, Matthay MA. PMID: 3952050.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    945. Intensive care unit: how stressful for physicians? Crit Care Med. 1986 Feb; 14(2):95-8. Eisendrath SJ, Link N, Matthay M. PMID: 3943330.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    946. Relationship of pleural effusions to pulmonary hemodynamics in patients with congestive heart failure. Am Rev Respir Dis. 1985 Dec; 132(6):1253-6. Wiener-Kronish JP, Matthay MA, Callen PW, Filly RA, Gamsu G, Staub NC. PMID: 3907444.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    947. Cellular basis for injury and repair in the adult respiratory distress syndrome. West J Med. 1985 Nov; 143(5):665-7. Matthay MA. PMID: 3909644; PMCID: PMC1306449.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    948. Pathophysiology of pulmonary edema. Clin Chest Med. 1985 Sep; 6(3):301-14. Matthay MA. PMID: 3907942.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    949. Long-term clearance of liquid and protein from the lungs of unanesthetized sheep. J Appl Physiol (1985). 1985 Sep; 59(3):928-34. Matthay MA, Berthiaume Y, Staub NC. PMID: 4055578.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    950. Resolution of pulmonary edema. Mechanisms of liquid, protein, and cellular clearance from the lung. Clin Chest Med. 1985 Sep; 6(3):521-45. Matthay MA. PMID: 3907951.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    951. Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study. Am Heart J. 1985 Aug; 110(2):335-41. Viquerat CE, Hansen RM, Botvinick EH, Dae MW, Wiener-Kronish JP, Matthay MA. PMID: 3875274.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    952. Elevated concentrations of leukotriene D4 in pulmonary edema fluid of patients with the adult respiratory distress syndrome. J Clin Immunol. 1984 Nov; 4(6):479-83. Matthay MA, Eschenbacher WL, Goetzl EJ. PMID: 6511865.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    953. Biologically active products of complement and acute lung injury in patients with the sepsis syndrome. Am Rev Respir Dis. 1984 Nov; 130(5):791-6. Weinberg PF, Matthay MA, Webster RO, Roskos KV, Goldstein IM, Murray JF. PMID: 6497161.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    954. Neurogenic pulmonary edema. Am Rev Respir Dis. 1984 Nov; 130(5):941-8. Colice GL, Matthay MA, Bass E, Matthay RA. PMID: 6388446.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    955. Morphologic and physiologic correlates of increased extravascular lung water. Surgery. 1984 Aug; 96(2):395-403. Bongard FS, Matthay M, Mackersie RC, Lewis FR. PMID: 6463867.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    956. Cardiovascular-pulmonary monitoring in the intensive care unit (Part 2). Chest. 1984 May; 85(5):656-68. Wiedemann HP, Matthay MA, Matthay RA. PMID: 6713975.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    957. Cardiovascular-pulmonary monitoring in the intensive care unit (Part 1). Chest. 1984 Apr; 85(4):537-49. Wiedemann HP, Matthay MA, Matthay RA. PMID: 6368142.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    958. Invasive hemodynamic monitoring in critically ill patients. Clin Chest Med. 1983 May; 4(2):233-49. Matthay MA. PMID: 6342922.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    959. Guillain-Barré syndrome: psychosocial aspects of management. Psychosomatics. 1983 May; 24(5):465-75. Eisendrath SJ, Matthay MA, Dunkel JA, Zimmerman JK, Layzer RB. PMID: 6878601.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    960. Hemodynamic management in the adult respiratory distress syndrome. Clin Chest Med. 1983 May; 4(2):251-68. Prewitt RM, Matthay MA, Ghignone M. PMID: 6342923.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    961. Overperfusion, hypoxia, and increased pressure cause only hydrostatic pulmonary edema in anesthetized sheep. Circ Res. 1983 Mar; 52(3):335-41. Landolt CC, Matthay MA, Albertine KH, Roos PJ, Wiener-Kronish JP, Staub NC. PMID: 6825224.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    962. Differential liquid and protein clearance from the alveoli of anesthetized sheep. J Appl Physiol Respir Environ Exerc Physiol. 1982 Jul; 53(1):96-104. Matthay MA, Landolt CC, Staub NC. PMID: 7118651.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    963. Adult respiratory distress syndrome complicating diabetic ketoacidosis. West J Med. 1981 Aug; 135(2):148-50. Russell J, Follansbee S, Matthay M. PMID: 6792789; PMCID: PMC1273047.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    964. Anatomic variations of efferent duct from caudal mediastinal lymph node in sheep. J Appl Physiol Respir Environ Exerc Physiol. 1981 Jun; 50(6):1372-4. Landolt CC, Matthay MA, Staub NC. PMID: 7263401.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    965. Chest mass with pleurisy. Chest. 1979 Oct; 76(4):453-4. Matthay MA, Addison TE, Ellinger G, Choy SH, Kaltreider HB. PMID: 477435.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    966. Thyrotoxicosis: comparison of effects of thyroid ablation and beta-adrenergic blockade on metabolic rate and ventilatory control. J Clin Endocrinol Metab. 1978 Mar; 46(3):491-500. Zwillich CW, Matthay M, Potts DE, Adler R, Hofeldt F, Weil JV. PMID: 221522.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    967. Acute pseudogout in the absence of synovial fluid Leukocytes. J Rheumatol. 1977; 4(3):303-6. Matthay M, Lindamood M, Steigerwald JC, Solomons C. PMID: 926107.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    968. Hypertrophic osteoarthropathy in adults with cystic fibrosis. Thorax. 1976 Oct; 31(5):572-5. Matthay MA, Matthay RA, Mills DM, Lakshminarayan S, Cotton E. PMID: 996819; PMCID: PMC470477.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    969. Grand mal seizure induced by oral theophylline. Thorax. 1976 Aug; 31(4):470-1. Matthay RA, Matthay MA, Weinberger MM. PMID: 823660; PMCID: PMC470462.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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