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Tom Arnold, MD

Title(s)Assistant Professor, Pediatrics
SchoolSchool of Medicine
Address1550 Fourth St
San Francisco CA 94158
Phone415-476-1034
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier. J Clin Invest. 2020 May 05. Santander N, Lizama CO, Meky E, McKinsey GL, Jung B, Sheppard D, Betsholtz C, Arnold TD. PMID: 32369453.
      View in: PubMed   Mentions:    Fields:    
    2. Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of ß-Catenin Signaling. Arterioscler Thromb Vasc Biol. 2019 07; 39(7):1432-1447. Jensen LD, Hot B, Ramsköld D, Germano RFV, Yokota C, Giatrellis S, Lauschke VM, Hubmacher D, Li MX, Hupe M, Arnold TD, Sandberg R, Frisén J, Trusohamn M, Martowicz A, Wisniewska-Kruk J, Nyqvist D, Adams RH, Apte SS, Vanhollebeke B, Stenman JM, Kele J. PMID: 31242033.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Impaired aVß8 and TGFß signaling lead to microglial dysmaturation and neuromotor dysfunction. J Exp Med. 2019 04 01; 216(4):900-915. Arnold TD, Lizama CO, Cautivo KM, Santander N, Lin L, Qiu H, Huang EJ, Liu C, Mukouyama YS, Reichardt LF, Zovein AC, Sheppard D. PMID: 30846482.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-ß Signaling in Developing Skin Vasculature. Cell Rep. 2017 03 21; 18(12):2991-3004. Yamazaki T, Nalbandian A, Uchida Y, Li W, Arnold TD, Kubota Y, Yamamoto S, Ema M, Mukouyama YS. PMID: 28329690.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    5. Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice. J Cereb Blood Flow Metab. 2018 03; 38(3):456-468. Jung B, Arnold TD, Raschperger E, Gaengel K, Betsholtz C. PMID: 28276839.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    6. The avß1 integrin plays a critical in vivo role in tissue fibrosis. Sci Transl Med. 2015 May 20; 7(288):288ra79. Reed NI, Jo H, Chen C, Tsujino K, Arnold TD, DeGrado WF, Sheppard D. PMID: 25995225.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    7. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J Cell Biol. 2015 Mar 16; 208(6):703-11. Sohet F, Lin C, Munji RN, Lee SY, Ruderisch N, Soung A, Arnold TD, Derugin N, Vexler ZS, Yen FT, Daneman R. PMID: 25753034.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    8. Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking aVß8-TGFß signaling in the brain. Development. 2014 Dec; 141(23):4489-99. Arnold TD, Niaudet C, Pang MF, Siegenthaler J, Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF. PMID: 25406396.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    9. Mesangial cell avß8-integrin regulates glomerular capillary integrity and repair. Am J Physiol Renal Physiol. 2014 Jun 15; 306(12):F1400-9. Lakhe-Reddy S, Li V, Arnold TD, Khan S, Schelling JR. PMID: 24740792.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. Targeting of av integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013 Dec; 19(12):1617-24. Henderson NC, Arnold TD, Katamura Y, Giacomini MM, Rodriguez JD, McCarty JH, Pellicoro A, Raschperger E, Betsholtz C, Ruminski PG, Griggs DW, Prinsen MJ, Maher JJ, Iredale JP, Lacy-Hulbert A, Adams RH, Sheppard D. PMID: 24216753.
      View in: PubMed   Mentions: 191     Fields:    Translation:AnimalsCells
    11. Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality. Dis Model Mech. 2013 Sep; 6(5):1205-12. Arnold TD, Zang K, Vallejo-Illarramendi A. PMID: 23744273.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-ß-TAK1-dependent mechanism. PLoS Biol. 2013; 11(4):e1001527. Shang Y, Doan CN, Arnold TD, Lee S, Tang AA, Reichardt LF, Huang EJ. PMID: 23565059.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    13. Defective retinal vascular endothelial cell development as a consequence of impaired integrin aVß8-mediated activation of transforming growth factor-ß. J Neurosci. 2012 Jan 25; 32(4):1197-206. Arnold TD, Ferrero GM, Qiu H, Phan IT, Akhurst RJ, Huang EJ, Reichardt LF. PMID: 22279205.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    14. Analysis of genomewide association signals for nonsyndromic cleft lip/palate in a Kenya African Cohort. Am J Med Genet A. 2011 Oct; 155A(10):2422-25. Weatherley-White RC, Ben S, Jin Y, Riccardi S, Arnold TD, Spritz RA. PMID: 22043487.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    15. From death to recovery following hypoxia ischemia: if TGFbeta is a central regulator, is integrin beta8 the switch? Neurotox Res. 2010 May; 17(4):418-20. Arnold TD, McQuillen PS. PMID: 20039156.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. Distribution of orofacial clefts and frequent occurrence of an unusual cleft variant in the Rift Valley of Kenya. Cleft Palate Craniofac J. 2007 Jul; 44(4):374-7. Spritz RA, Arnold TD, Buonocore S, Carter D, Fingerlin T, Odero WW, Wambani JO, Tenge RK, Weatherley-White RC. PMID: 17608554.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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