David Sretavan, MD, PhD

Title(s)Professor Emeritus, Ophthalmology
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    McGill UniversityB.Sc. Honors1980Physiology
    Stanford UniversityM.D.1987Medicine
    Stanford UniversityPh.D.1987Neurobiology
    Rockefeller UniversityPostdoctoral Research1990Laboratory of Neurobiology
    University of California San FranciscoPostdoctoral Research1992HHMI

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Intraocular Pressure Sensing Using Light
    NIH/NEI R01EY024582Dec 1, 2015 - Nov 30, 2019
    Role: Principal Investigator
    Microscale Axon Repair As A Novel Paradigm For Nerve Injuries
    NIH/NINDS R01NS062690Jul 15, 2008 - Dec 30, 2012
    Role: Principal Investigator
    Axon Guidance Molecules and Optic Nerve Disease
    NIH/NEI R03EY016691Aug 1, 2005 - Jul 31, 2008
    Role: Principal Investigator
    Enhanced Axon Sparing In Glaucoma Through Augmentation Of EphB/ephrin B Signaling
    NIH/NEI R01EY010688Jul 1, 1994 - Jun 30, 2016
    Role: Principal Investigator
    NIH/NEI P30EY002162Dec 1, 1977 - Jun 30, 2019
    Role: Co-Investigator
    California National Primate Research Center
    NIH P51RR000169Jun 1, 1975 - Apr 30, 2015
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Narasimhan V, Siddique RH, Lee JO, Kumar S, Ndjamen B, Du J, Hong N, Sretavan D, Choo H. Multifunctional biophotonic nanostructures inspired by the longtail glasswing butterfly for medical devices. Nat Nanotechnol. 2018 Jun; 13(6):512-519. PMID: 29713074.
      View in: PubMed
    2. Kim KH, Lee JO, Du J, Sretavan D, Choo H. Real-Time In Vivo Intraocular Pressure Monitoring using an Optomechanical Implant and an Artificial Neural Network. IEEE Sens J. 2017; 17(22):7394-7404. PMID: 29422780.
      View in: PubMed
    3. Lee JO, Narasimhan V, Du J, Ndjamen B, Sretavan D, Choo H. Biocompatible Multifunctional Black-Silicon for Implantable Intraocular Sensor. Adv Healthc Mater. 2017 Feb; 6(4). PMID: 28081305.
      View in: PubMed
    4. Song Y, Sretavan D, Salegio EA, Berg J, Huang X, Cheng T, Xiong X, Meltzer S, Han C, Nguyen TT, Bresnahan JC, Beattie MS, Jan LY, Jan YN. Regulation of axon regeneration by the RNA repair and splicing pathway. Nat Neurosci. 2015 Jun; 18(6):817-25. PMID: 25961792.
      View in: PubMed
    5. Fu CT, Sretavan DW. Ectopic vesicular glutamate release at the optic nerve head and axon loss in mouse experimental glaucoma. J Neurosci. 2012 Nov 07; 32(45):15859-76. PMID: 23136425; PMCID: PMC3752140.
    6. Ruggiero J, Keller C, Porco T, Naseri A, Sretavan DW. Rabbit models for continuous curvilinear capsulorhexis instruction. J Cataract Refract Surg. 2012 Jul; 38(7):1266-70. PMID: 22727296.
      View in: PubMed
    7. Fu CT, Sretavan D. Involvement of EphB/Ephrin-B signaling in axonal survival in mouse experimental glaucoma. Invest Ophthalmol Vis Sci. 2012 Jan 05; 53(1):76-84. PMID: 22064993; PMCID: PMC3292385.
    8. Chang WC, Hawkes E, Keller CG, Sretavan DW. Axon repair: surgical application at a subcellular scale. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 Mar-Apr; 2(2):151-61. PMID: 20101712; PMCID: PMC3150872.
    9. Fu CT, Tran T, Sretavan D. Axonal/glial upregulation of EphB/ephrin-B signaling in mouse experimental ocular hypertension. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):991-1001. PMID: 19815726; PMCID: PMC2868457.
    10. Fu CT, Sretavan D. Laser-induced ocular hypertension in albino CD-1 mice. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):980-90. PMID: 19815738; PMCID: PMC2868470.
    11. Chang WC, Sretavan DW. Single cell and neural process experimentation using laterally applied electrical fields between pairs of closely apposed microelectrodes with vertical sidewalls. Biosens Bioelectron. 2009 Aug 15; 24(12):3600-7. PMID: 19535240; PMCID: PMC2907170.
    12. Chang WC, Kliot M, Sretavan DW. Microtechnology and nanotechnology in nerve repair. Neurol Res. 2008 Dec; 30(10):1053-62. PMID: 19079980.
      View in: PubMed
    13. Chang WC, Sretavan DW. Novel high-resolution micropatterning for neuron culture using polylysine adsorption on a cell repellant, plasma-polymerized background. Langmuir. 2008 Nov 18; 24(22):13048-57. PMID: 18925765; PMCID: PMC2767107.
    14. Du J, Tran T, Fu C, Sretavan DW. Upregulation of EphB2 and ephrin-B2 at the optic nerve head of DBA/2J glaucomatous mice coincides with axon loss. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5567-81. PMID: 18055806.
      View in: PubMed
    15. Chang WC, Hawkes EA, Kliot M, Sretavan DW. In vivo use of a nanoknife for axon microsurgery. Neurosurgery. 2007 Oct; 61(4):683-91; discussion 691-2. PMID: 17986929.
      View in: PubMed
    16. Chang WC, Sretavan DW. Microtechnology in medicine: the emergence of surgical microdevices. Clin Neurosurg. 2007; 54:137-47. PMID: 18504911.
      View in: PubMed
    17. Liu X, Hawkes E, Ishimaru T, Tran T, Sretavan DW. EphB3: an endogenous mediator of adult axonal plasticity and regrowth after CNS injury. J Neurosci. 2006 Mar 22; 26(12):3087-101. PMID: 16554460.
      View in: PubMed
    18. Chang WC, Keller CG, Sretavan DW. Isolation of neuronal substructures and precise neural microdissection using a nanocutting device. J Neurosci Methods. 2006 Apr 15; 152(1-2):83-90. PMID: 16253341.
      View in: PubMed
    19. Sretavan DW, Chang W, Hawkes E, Keller C, Kliot M. Microscale surgery on single axons. Neurosurgery. 2005 Oct; 57(4):635-46; discussion 635-46. PMID: 16239875.
      View in: PubMed
    20. Kantor DB, Chivatakarn O, Peer KL, Oster SF, Inatani M, Hansen MJ, Flanagan JG, Yamaguchi Y, Sretavan DW, Giger RJ, Kolodkin AL. Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans. Neuron. 2004 Dec 16; 44(6):961-75. PMID: 15603739.
      View in: PubMed
    21. Goldberg JL, Vargas ME, Wang JT, Mandemakers W, Oster SF, Sretavan DW, Barres BA. An oligodendrocyte lineage-specific semaphorin, Sema5A, inhibits axon growth by retinal ganglion cells. J Neurosci. 2004 May 26; 24(21):4989-99. PMID: 15163691.
      View in: PubMed
    22. Suh LH, Oster SF, Soehrman SS, Grenningloh G, Sretavan DW. L1/Laminin modulation of growth cone response to EphB triggers growth pauses and regulates the microtubule destabilizing protein SCG10. J Neurosci. 2004 Feb 25; 24(8):1976-86. PMID: 14985440.
      View in: PubMed
    23. Beggs HE, Schahin-Reed D, Zang K, Goebbels S, Nave KA, Gorski J, Jones KR, Sretavan D, Reichardt LF. FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies. Neuron. 2003 Oct 30; 40(3):501-14. PMID: 14642275; PMCID: PMC2758566.
    24. Oster SF, Bodeker MO, He F, Sretavan DW. Invariant Sema5A inhibition serves an ensheathing function during optic nerve development. Development. 2003 Feb; 130(4):775-84. PMID: 12506007.
      View in: PubMed
    25. Marcus RC, Shimamura K, Sretavan D, Lai E, Rubenstein JL, Mason CA. Domains of regulatory gene expression and the developing optic chiasm: correspondence with retinal axon paths and candidate signaling cells. J Comp Neurol. 1999 Jan 18; 403(3):346-58. PMID: 9886035.
      View in: PubMed
    26. Reichardt LF, Bossy B, de Curtis I, Neugebauer KM, Venstrom K, Sretavan D. Adhesive interactions that regulate development of the retina and primary visual projection. Cold Spring Harb Symp Quant Biol. 1992; 57:419-29. PMID: 1339677.
      View in: PubMed