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Lily Jan, PhD

Title(s)Professor, Physiology
SchoolSchool of Medicine
Address1550 Fourth St
San Francisco CA 94158
Phone415-476-8751
ORCID ORCID Icon0000-0003-3938-8498 Additional info
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    Other Positions
    Title(s)Howard Hughes Medical Institute investigator


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    Central neuronal circuitry for homeostatic thermoregulation modulated by brain temperature
    NIH/NINDS R01NS116588Apr 15, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Molecular and Genetic Studies of TMEM16C Control of Thermoregulation and Neuronal Excitability
    NIH/NINDS R01NS108946Feb 15, 2020 - Jan 31, 2025
    Role: Principal Investigator
    Illuminating Druggable Dark Matter
    NIH/NIDDK U24DK116214Sep 15, 2017 - Aug 31, 2023
    Role: Co-Principal Investigator
    (PQA1) The antipsychotic thioridazine protects against medulloblastoma (MB): volu
    NIH/NCI R01CA185039Jun 1, 2014 - May 31, 2018
    Role: Principal Investigator
    Molecular, genetic & physiological studies of calcium-activated chloride channels
    NIH/NINDS R01NS069229Jul 15, 2011 - Jun 30, 2018
    Role: Principal Investigator
    Genetic Studies of the Synapse
    NIH/NIMH R37MH065334Sep 1, 2001 - Jun 30, 2011
    Role: Principal Investigator
    Genetic Studies of the Synapse
    NIH/NIMH R01MH065334Sep 1, 2001 - Jun 30, 2006
    Role: Principal Investigator
    ASSEMBLY AND TARGETING OF NEURAL RECEPTORS AND CHANNELS
    NIH/NIMH P50MH063981Aug 15, 2001 - Jul 31, 2007
    Role: Co-Investigator
    LONGTERM CHANGES IN THE MAMMALIAN BRAIN
    NIH/NIMH P50MH048200Sep 1, 1991 - Aug 31, 2002
    Role: Principal Investigator
    GENETIC AND IMMUNOLOGICAL STUDIES OF NEURAL DEVELOPMENT
    NIH/NINDS R01NS019191Jan 1, 1983 - Jun 30, 1988
    Role: Principal Investigator
    GENETIC STUDIES OF THE SYNAPSE
    NIH/NINDS R01NS015963Jan 1, 1980 - Jun 30, 2002
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TMEM16K is an interorganelle regulator of endosomal sorting. Nat Commun. 2020 07 03; 11(1):3298. Petkovic M, Oses-Prieto J, Burlingame A, Jan LY, Jan YN. PMID: 32620747.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14; 9. He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY. PMID: 32286221.
      View in: PubMed   Mentions: 1     Fields:    
    3. Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms. Annu Rev Neurosci. 2020 Jul 08; 43:207-229. Jin P, Jan LY, Jan YN. PMID: 32084327.
      View in: PubMed   Mentions: 4     Fields:    
    4. Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors. Genes Dev. 2019 12 01; 33(23-24):1739-1750. Piggott BJ, Peters CJ, He Y, Huang X, Younger S, Jan LY, Jan YN. PMID: 31753914.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala. Elife. 2019 09 04; 8. Li KX, He M, Ye W, Simms J, Gill M, Xiang X, Jan YN, Jan LY. PMID: 31482844.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Rep. 2019 Jul 30; 28(5):1385. Feng S, Dang S, Han TW, Ye W, Jin P, Cheng T, Li J, Jan YN, Jan LY, Cheng Y. PMID: 31365878.
      View in: PubMed   Mentions: 1     Fields:    
    7. TMEM16B Calcium-Activated Chloride Channels Regulate Action Potential Firing in Lateral Septum and Aggression in Male Mice. J Neurosci. 2019 09 04; 39(36):7102-7117. Wang L, Simms J, Peters CJ, Tynan-La Fontaine M, Li K, Gill TM, Jan YN, Jan LY. PMID: 31320449.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity. Elife. 2019 07 18; 8. Ye W, Han TW, He M, Jan YN, Jan LY. PMID: 31318330.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    9. Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area. Neuron. 2019 Jul 17; 103(2):349. Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY. PMID: 31319050.
      View in: PubMed   Mentions:    Fields:    
    10. Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling. Cell Rep. 2019 07 09; 28(2):567-579.e4. Feng S, Dang S, Han TW, Ye W, Jin P, Cheng T, Li J, Jan YN, Jan LY, Cheng Y. PMID: 31291589.
      View in: PubMed   Mentions: 7     Fields:    
    11. The multifaceted role of TMEM16A in cancer. Cell Calcium. 2019 09; 82:102050. Crottès D, Jan LY. PMID: 31279157.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    12. TMEM16A controls EGF-induced calcium signaling implicated in pancreatic cancer prognosis. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):13026-13035. Crottès D, Lin YT, Peters CJ, Gilchrist JM, Wiita AP, Jan YN, Jan LY. PMID: 31182586.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area. Neuron. 2019 07 17; 103(2):309-322.e7. Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY. PMID: 31151773.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration. Neuron. 2019 04 17; 102(2):373-389.e6. Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, Xiang Y, Rompolas P, Jan LY, Jan YN. PMID: 30819546.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    15. Glial ensheathment of the somatodendritic compartment regulates sensory neuron structure and activity. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):5126-5134. Yadav S, Younger SH, Zhang L, Thompson-Peer KL, Li T, Jan LY, Jan YN. PMID: 30804200.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    16. Chemically induced vesiculation as a platform for studying TMEM16F activity. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1309-1318. Han TW, Ye W, Bethel NP, Zubia M, Kim A, Li KH, Burlingame AL, Grabe M, Jan YN, Jan LY. PMID: 30622179.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    17. Far away from the lamppost. PLoS Biol. 2018 12; 16(12):e3000067. Oprea TI, Jan L, Johnson GL, Roth BL, Ma'ayan A, Schürer S, Shoichet BK, Sklar LA, McManus MT. PMID: 30532236.
      View in: PubMed   Mentions: 1     Fields:    
    18. Activation of orexin system facilitates anesthesia emergence and pain control. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):E10740-E10747. Zhou W, Cheung K, Kyu S, Wang L, Guan Z, Kurien PA, Bickler PE, Jan LY. PMID: 30348769.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    19. Influences: Cold Spring Harbor summer courses and Drosophila melanogaster neurogenetics. J Gen Physiol. 2018 06 04; 150(6):773-775. Jan LY, Jan YN. PMID: 29769227.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    20. Dendrite regeneration of adult Drosophila sensory neurons diminishes with aging and is inhibited by epidermal-derived matrix metalloproteinase 2. Genes Dev. 2018 03 01; 32(5-6):402-414. DeVault L, Li T, Izabel S, Thompson-Peer KL, Jan LY, Jan YN. PMID: 29563183.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    21. Force-activated ion channels in close-up. Nature. 2018 02 22; 554(7693):469-470. Jan YN, Jan LY. PMID: 29469134.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    22. The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron. 2018 03 07; 97(5):1063-1077.e4. Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan LY. PMID: 29478917.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    23. Force-activated ion channels in close-up. Nature. 2018 Feb; 554(7693):469-470. Jan YN, Jan LY. PMID: 32094930.
      View in: PubMed   Mentions:    Fields:    
    24. Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1667-E1674. Ye W, Han TW, Nassar LM, Zubia M, Jan YN, Jan LY. PMID: 29382763.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    25. Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature. 2017 12 21; 552(7685):426-429. Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL, Cheng Y, Jan LY. PMID: 29236684.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    26. Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis. Proc Natl Acad Sci U S A. 2017 12 26; 114(52):E11161-E11169. He M, Ye W, Wang WJ, Sison ES, Jan YN, Jan LY. PMID: 29229864.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons. Cell Rep. 2017 Oct 24; 21(4):859-866. Meltzer S, Bagley JA, Perez GL, O'Brien CE, DeVault L, Guo Y, Jan LY, Jan YN. PMID: 29069593.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    28. Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning. Neuron. 2017 Aug 30; 95(5):1103-1111.e4. Zhang Y, Zhang Z, Xiao S, Tien J, Le S, Le T, Jan LY, Yang H. PMID: 28858616.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    29. Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity. Cell Rep. 2017 Aug 22; 20(8):1855-1866. Orr BO, Gorczyca D, Younger MA, Jan LY, Jan YN, Davis GW. PMID: 28834749.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    30. Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature. 2017 07 06; 547(7661):118-122. Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan LY, Jan YN, Cheng Y. PMID: 28658211.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    31. Age-dependent diastolic heart failure in an in vivo Drosophila model. Elife. 2017 03 22; 6. Klassen MP, Peters CJ, Zhou S, Williams HH, Jan LY, Jan YN. PMID: 28328397.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    32. TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation. Neuron. 2017 Jan 18; 93(2):379-393. Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan LY, Jan YN. PMID: 28065648.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    33. A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles. J Neurosci. 2016 11 02; 36(44):11275-11282. Li J, Zhang W, Guo Z, Wu S, Jan LY, Jan YN. PMID: 27807168.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    34. N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels. J Physiol. 2016 11 15; 594(22):6701-6713. Thayer DA, Yang SB, Jan YN, Jan LY. PMID: 27377235.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    35. In vivo dendrite regeneration after injury is different from dendrite development. Genes Dev. 2016 08 01; 30(15):1776-89. Thompson-Peer KL, DeVault L, Li T, Jan LY, Jan YN. PMID: 27542831.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    36. Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7243-8. Guo Y, Wang Y, Zhang W, Meltzer S, Zanini D, Yu Y, Li J, Cheng T, Guo Z, Wang Q, Jacobs JS, Sharma Y, Eberl DF, Göpfert MC, Jan LY, Jan YN, Wang Z. PMID: 27298354.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    37. Phosphorylation of ß-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. 2016 05 04; 90(3):551-63. Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN. PMID: 27112495.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    38. Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons. Neuron. 2016 Feb 17; 89(4):741-55. Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan LY, Jan YN. PMID: 26853303.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    39. Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis. Sci Transl Med. 2015 Nov 25; 7(315):315ra190. Headland SE, Jones HR, Norling LV, Kim A, Souza PR, Corsiero E, Gil CD, Nerviani A, Dell'Accio F, Pitzalis C, Oliani SM, Jan LY, Perretti M. PMID: 26606969.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    40. Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury. Cell Rep. 2015 Nov 10; 13(6):1246-1257. Petitjean H, Pawlowski SA, Fraine SL, Sharif B, Hamad D, Fatima T, Berg J, Brown CM, Jan LY, Ribeiro-da-Silva A, Braz JM, Basbaum AI, Sharif-Naeini R. PMID: 26527000.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    41. Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel. Cell. 2015 Sep 10; 162(6):1391-403. Zhang W, Cheng LE, Kittelmann M, Li J, Petkovic M, Cheng T, Jin P, Guo Z, Göpfert MC, Jan LY, Jan YN. PMID: 26359990.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    42. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nat Neurosci. 2015 Sep; 18(9):1236-46. Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan LY. PMID: 26258683.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    43. Regulation of axon regeneration by the RNA repair and splicing pathway. Nat Neurosci. 2015 Jun; 18(6):817-25. Song Y, Sretavan D, Salegio EA, Berg J, Huang X, Cheng T, Xiong X, Meltzer S, Han C, Nguyen TT, Bresnahan JC, Beattie MS, Jan LY, Jan YN. PMID: 25961792.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    44. The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. Elife. 2015 Mar 12; 4. Soba P, Han C, Zheng Y, Perea D, Miguel-Aliaga I, Jan LY, Jan YN. PMID: 25764303.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    45. Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3547-52. Peters CJ, Yu H, Tien J, Jan YN, Li M, Jan LY. PMID: 25733897.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    46. Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):2935-41. Shen Y, Ge WP, Li Y, Hirano A, Lee HY, Rohlmann A, Missler M, Tsien RW, Jan LY, Fu YH, Ptácek LJ. PMID: 25730884.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    47. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Neuron. 2014 Dec 03; 84(5):968-82. Ultanir SK, Yadav S, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan LY, Jan YN. PMID: 25456499.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    48. Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila. Cell Rep. 2014 Nov 20; 9(4):1446-58. Gorczyca DA, Younger S, Meltzer S, Kim SE, Cheng L, Song W, Lee HY, Jan LY, Jan YN. PMID: 25456135.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    49. Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae. Elife. 2014 Oct 30; 3. Zhang W, Yan Z, Li B, Jan LY, Jan YN. PMID: 25358089.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    50. Common variants associated with general and MMR vaccine-related febrile seizures. Nat Genet. 2014 Dec; 46(12):1274-82. Feenstra B, Pasternak B, Geller F, Carstensen L, Wang T, Huang F, Eitson JL, Hollegaard MV, Svanström H, Vestergaard M, Hougaard DM, Schoggins JW, Jan LY, Melbye M, Hviid A. PMID: 25344690.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    51. Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function. Genes Dev. 2014 Sep 01; 28(17):1940-56. Bagley JA, Yan Z, Zhang W, Wildonger J, Jan LY, Jan YN. PMID: 25184680.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    52. Targeting potassium channels in cancer. J Cell Biol. 2014 Jul 21; 206(2):151-62. Huang X, Jan LY. PMID: 25049269.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    53. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 2014 Jun 30; 3. Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. PMID: 24980701.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    54. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun; 20(6):624-32. Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. PMID: 24836577.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    55. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nat Commun. 2014 May 15; 5:3626. Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X. PMID: 24832154.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    56. Krüppel mediates the selective rebalancing of ion channel expression. Neuron. 2014 May 07; 82(3):537-44. Parrish JZ, Kim CC, Tang L, Bergquist S, Wang T, Derisi JL, Jan LY, Jan YN, Davis GW. PMID: 24811378.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    57. Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7331-6. Rumpf S, Bagley JA, Thompson-Peer KL, Zhu S, Gorczyca D, Beckstead RB, Jan LY, Jan YN. PMID: 24799714.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    58. Lily Jan. Curr Biol. 2014 Mar 17; 24(6):R212-3. Jan L. PMID: 24795915.
      View in: PubMed   Mentions:    Fields:    
    59. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron. 2014 Feb 05; 81(3):544-560. Han C, Song Y, Xiao H, Wang D, Franc NC, Jan LY, Jan YN. PMID: 24412417.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    60. A PDF/NPF neuropeptide signaling circuitry of male Drosophila melanogaster controls rival-induced prolonged mating. Neuron. 2013 Dec 04; 80(5):1190-205. Kim WJ, Jan LY, Jan YN. PMID: 24314729.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    61. Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila. Nat Neurosci. 2014 Jan; 17(1):81-8. Yuan Q, Song Y, Yang CH, Jan LY, Jan YN. PMID: 24241395.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    62. Subdued, a TMEM16 family Ca²?-activated Cl?channel in Drosophila melanogaster with an unexpected role in host defense. Elife. 2013 Nov 05; 2:e00862. Wong XM, Younger S, Peters CJ, Jan YN, Jan LY. PMID: 24192034.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    63. Conduits of life's spark: a perspective on ion channel research since the birth of neuron. Neuron. 2013 Oct 30; 80(3):658-74. Isacoff EY, Jan LY, Minor DL. PMID: 24183018.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    64. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2013 Sep 10; 2:e00508. Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. PMID: 24040509.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    65. Making antisense of pain. Nat Neurosci. 2013 Aug; 16(8):986-7. Han TW, Jan LY. PMID: 23887131.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    66. Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13612-7. Zhang W, Yan Z, Jan LY, Jan YN. PMID: 23898199.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    67. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci. 2013 Sep; 16(9):1284-90. Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan YN, Basbaum AI, Jan LY. PMID: 23872594.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    68. Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6352-7. Tien J, Lee HY, Minor DL, Jan YN, Jan LY. PMID: 23576756.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
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    334. atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system. Cell. 1993 Jul 02; 73(7):1307-21. Jarman AP, Grau Y, Jan LY, Jan YN. PMID: 8324823.
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    335. Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis. Cell. 1993 Jun 04; 73(5):953-65. Ruohola-Baker H, Grell E, Chou TB, Baker D, Jan LY, Jan YN. PMID: 8500182.
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    336. The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J. 1993 Jun; 12(6):2586. Boulianne GL, de la Concha A, Campos-Ortega JA, Jan LY, Jan YN. PMID: 8508781.
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    344. A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. Mol Cell Biol. 1993 Jan; 13(1):105-13. Feder JN, Jan LY, Jan YN. PMID: 8417318.
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    345. deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product. Genes Dev. 1992 Nov; 6(11):2137-51. Bier E, Vaessin H, Younger-Shepherd S, Jan LY, Jan YN. PMID: 1427077.
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    346. deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination. Cell. 1992 Sep 18; 70(6):911-22. Younger-Shepherd S, Vaessin H, Bier E, Jan LY, Jan YN. PMID: 1525829.
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    347. The big brain gene of Drosophila functions to control the number of neuronal precursors in the peripheral nervous system. Development. 1992 Sep; 116(1):31-40. Rao Y, Bodmer R, Jan LY, Jan YN. PMID: 1483394.
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    356. prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell. 1991 Nov 29; 67(5):941-53. Vaessin H, Grell E, Wolff E, Bier E, Jan LY, Jan YN. PMID: 1720353.
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    357. The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J. 1991 Oct; 10(10):2975-83. Boulianne GL, de la Concha A, Campos-Ortega JA, Jan LY, Jan YN. PMID: 1717258.
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    366. A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila. Development. 1990 Nov; 110(3):661-9. Bodmer R, Jan LY, Jan YN. PMID: 1982429.
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    374. rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev. 1990 Feb; 4(2):190-203. Bier E, Jan LY, Jan YN. PMID: 2110920.
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    378. Spider toxins selectively block calcium currents in Drosophila. Neuron. 1989 Dec; 3(6):767-72. Leung HT, Branton WD, Phillips HS, Jan L, Byerly L. PMID: 2642017.
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    380. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell. 1989 Jul 28; 58(2):349-60. Uemura T, Shepherd S, Ackerman L, Jan LY, Jan YN. PMID: 2752427.
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    382. daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex. Cell. 1988 Dec 23; 55(6):1061-7. Caudy M, Vässin H, Brand M, Tuma R, Jan LY, Jan YN. PMID: 3203380.
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    386. The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila. Genes Dev. 1988 Jul; 2(7):843-52. Caudy M, Grell EH, Dambly-Chaudière C, Ghysen A, Jan LY, Jan YN. PMID: 3209070.
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