Loading...

Lily Jan, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentPhysiology
Address1550 Fourth St
San Francisco CA 94158
Phone415-476-8748
vCardDownload vCard
    Other Positions
    TitleHoward Hughes Medical Institute investigator


    Collapse Research 
    Collapse Research Activities and Funding
    Illuminating Druggable Dark Matter
    NIH/NIDDK U24DK116214Sep 15, 2017 - Aug 31, 2023
    Role: Co-Principal Investigator
    (PQA1) The antipsychotic thioridazine protects against medulloblastoma (MB): volu
    NIH/NCI R01CA185039Jun 1, 2014 - May 31, 2018
    Role: Principal Investigator
    Molecular, genetic & physiological studies of calcium-activated chloride channels
    NIH/NINDS R01NS069229Jul 15, 2011 - Jun 30, 2018
    Role: Principal Investigator
    Genetic Studies of the Synapse
    NIH/NIMH R01MH065334Sep 1, 2001 - Apr 30, 2021
    Role: Principal Investigator
    Genetic Studies of the Synapse
    NIH/NIMH R37MH065334Sep 1, 2001 - Apr 30, 2016
    Role: Principal Investigator
    ASSEMBLY AND TARGETING OF NEURAL RECEPTORS AND CHANNELS
    NIH/NIMH P50MH063981Aug 15, 2001 - Jul 31, 2007
    Role: Co-Investigator
    LONGTERM CHANGES IN THE MAMMALIAN BRAIN
    NIH/NIMH P50MH048200Sep 1, 1991 - Aug 31, 2002
    Role: Principal Investigator
    GENETIC AND IMMUNOLOGICAL STUDIES OF NEURAL DEVELOPMENT
    NIH/NINDS R01NS019191Jan 1, 1983 - Jun 30, 1988
    Role: Principal Investigator
    GENETIC STUDIES OF THE SYNAPSE
    NIH/NINDS R01NS015963Jan 1, 1980 - Jun 30, 2002
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Jan L, Jan YN. Influences: Cold Spring Harbor summer courses and Drosophila melanogaster neurogenetics. J Gen Physiol. 2018 May 16. PMID: 29769227.
      View in: PubMed
    2. DeVault L, Li T, Izabel S, Thompson-Peer KL, Jan L, Jan YN. Dendrite regeneration of adult Drosophila sensory neurons diminishes with aging and is inhibited by epidermal-derived matrix metalloproteinase 2. Genes Dev. 2018 Mar 01; 32(5-6):402-414. PMID: 29563183.
      View in: PubMed
    3. Jan YN, Jan L. Force-activated ion channels in close-up. Nature. 2018 Feb 22; 554(7693):469-470. PMID: 29469134.
      View in: PubMed
    4. Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan L. The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron. 2018 Mar 07; 97(5):1063-1077.e4. PMID: 29478917.
      View in: PubMed
    5. Ye W, Han TW, Nassar LM, Zubia M, Jan YN, Jan L. Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proc Natl Acad Sci U S A. 2018 Feb 13; 115(7):E1667-E1674. PMID: 29382763.
      View in: PubMed
    6. Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL, Cheng Y, Jan L. Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature. 2017 12 21; 552(7685):426-429. PMID: 29236684.
      View in: PubMed
    7. He M, Ye W, Wang WJ, Sison ES, Jan YN, Jan L. Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis. Proc Natl Acad Sci U S A. 2017 Dec 26; 114(52):E11161-E11169. PMID: 29229864.
      View in: PubMed
    8. Meltzer S, Bagley JA, Perez GL, O'Brien CE, DeVault L, Guo Y, Jan L, Jan YN. Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons. Cell Rep. 2017 Oct 24; 21(4):859-866. PMID: 29069593.
      View in: PubMed
    9. Zhang Y, Zhang Z, Xiao S, Tien J, Le S, Le T, Jan L, Yang H. Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning. Neuron. 2017 Aug 30; 95(5):1103-1111.e4. PMID: 28858616.
      View in: PubMed
    10. Orr BO, Gorczyca D, Younger MA, Jan L, Jan YN, Davis GW. Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity. Cell Rep. 2017 Aug 22; 20(8):1855-1866. PMID: 28834749.
      View in: PubMed
    11. Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Cheng T, Jan L, Jan YN, Cheng Y. Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature. 2017 07 06; 547(7661):118-122. PMID: 28658211.
      View in: PubMed
    12. Klassen MP, Peters CJ, Zhou S, Williams HH, Jan L, Jan YN. Age-dependent diastolic heart failure in an in vivo Drosophila model. Elife. 2017 03 22; 6. PMID: 28328397.
      View in: PubMed
    13. Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan L, Jan YN. TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation. Neuron. 2017 Jan 18; 93(2):379-393. PMID: 28065648.
      View in: PubMed
    14. Li J, Zhang W, Guo Z, Wu S, Jan L, Jan YN. A Defensive Kicking Behavior in Response to Mechanical Stimuli Mediated by Drosophila Wing Margin Bristles. J Neurosci. 2016 Nov 02; 36(44):11275-11282. PMID: 27807168.
      View in: PubMed
    15. Thayer DA, Yang SB, Jan YN, Jan L. N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels. J Physiol. 2016 11 15; 594(22):6701-6713. PMID: 27377235.
      View in: PubMed
    16. Thompson-Peer KL, DeVault L, Li T, Jan L, Jan YN. In vivo dendrite regeneration after injury is different from dendrite development. Genes Dev. 2016 08 01; 30(15):1776-89. PMID: 27542831; PMCID: PMC5002981 [Available on 02/01/17].
    17. Guo Y, Wang Y, Zhang W, Meltzer S, Zanini D, Yu Y, Li J, Cheng T, Guo Z, Wang Q, Jacobs JS, Sharma Y, Eberl DF, Göpfert MC, Jan L, Jan YN, Wang Z. Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7243-8. PMID: 27298354; PMCID: PMC4932980 [Available on 12/28/16].
    18. Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan L, Vale RD, Wiita AP, Jan YN. Phosphorylation of ß-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. 2016 05 04; 90(3):551-63. PMID: 27112495; PMCID: PMC4860041 [Available on 05/04/17].
    19. Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan L, Jan YN. Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons. Neuron. 2016 Feb 17; 89(4):741-55. PMID: 26853303; PMCID: PMC4760923 [Available on 02/17/17].
    20. Headland SE, Jones HR, Norling LV, Kim A, Souza PR, Corsiero E, Gil CD, Nerviani A, Dell'Accio F, Pitzalis C, Oliani SM, Jan L, Perretti M. Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis. Sci Transl Med. 2015 Nov 25; 7(315):315ra190. PMID: 26606969.
      View in: PubMed
    21. Petitjean H, Pawlowski SA, Fraine SL, Sharif B, Hamad D, Fatima T, Berg J, Brown CM, Jan L, Ribeiro-da-Silva A, Braz JM, Basbaum AI, Sharif-Naeini R. Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury. Cell Rep. 2015 Nov 10; 13(6):1246-1257. PMID: 26527000.
      View in: PubMed
    22. Zhang W, Cheng LE, Kittelmann M, Li J, Petkovic M, Cheng T, Jin P, Guo Z, Göpfert MC, Jan L, Jan YN. Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel. Cell. 2015 Sep 10; 162(6):1391-403. PMID: 26359990; PMCID: PMC4568062.
    23. Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, Garzia L, Wu X, Remke M, Forester CM, Kim CC, Weiss WA, James CD, Shuman MA, Bader GD, Mueller S, Taylor MD, Jan YN, Jan L. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nat Neurosci. 2015 Sep; 18(9):1236-46. PMID: 26258683; PMCID: PMC4639927.
    24. Song Y, Sretavan D, Salegio EA, Berg J, Huang X, Cheng T, Xiong X, Meltzer S, Han C, Nguyen TT, Bresnahan JC, Beattie MS, Jan L, Jan YN. Regulation of axon regeneration by the RNA repair and splicing pathway. Nat Neurosci. 2015 Jun; 18(6):817-25. PMID: 25961792; PMCID: PMC4446171.
    25. Soba P, Han C, Zheng Y, Perea D, Miguel-Aliaga I, Jan L, Jan YN. The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. Elife. 2015 Mar 12; 4. PMID: 25764303; PMCID: PMC4391025.
    26. Peters CJ, Yu H, Tien J, Jan YN, Li M, Jan L. Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3547-52. PMID: 25733897; PMCID: PMC4371966.
    27. Shen Y, Ge WP, Li Y, Hirano A, Lee HY, Rohlmann A, Missler M, Tsien RW, Jan L, Fu YH, Ptácek LJ. Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):2935-41. PMID: 25730884; PMCID: PMC4364199.
    28. Ultanir SK, Yadav S, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan L, Jan YN. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Neuron. 2014 Dec 03; 84(5):968-82. PMID: 25456499; PMCID: PMC4407996.
    29. Gorczyca DA, Younger S, Meltzer S, Kim SE, Cheng L, Song W, Lee HY, Jan L, Jan YN. Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila. Cell Rep. 2014 Nov 20; 9(4):1446-58. PMID: 25456135; PMCID: PMC4254518.
    30. Zhang W, Yan Z, Li B, Jan L, Jan YN. Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae. Elife. 2014 Oct 30; 3. PMID: 25358089; PMCID: PMC4244571.
    31. Feenstra B, Pasternak B, Geller F, Carstensen L, Wang T, Huang F, Eitson JL, Hollegaard MV, Svanström H, Vestergaard M, Hougaard DM, Schoggins JW, Jan L, Melbye M, Hviid A. Common variants associated with general and MMR vaccine-related febrile seizures. Nat Genet. 2014 Dec; 46(12):1274-82. PMID: 25344690; PMCID: PMC4244308.
    32. Bagley JA, Yan Z, Zhang W, Wildonger J, Jan L, Jan YN. Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function. Genes Dev. 2014 Sep 01; 28(17):1940-56. PMID: 25184680; PMCID: PMC4197945.
    33. Huang X, Jan L. Targeting potassium channels in cancer. J Cell Biol. 2014 Jul 21; 206(2):151-62. PMID: 25049269; PMCID: PMC4107787.
    34. Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan L, Yang H. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 2014 Jun 30; 3. PMID: 24980701; PMCID: PMC4112547.
    35. Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan L, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun; 20(6):624-32. PMID: 24836577; PMCID: PMC4048325.
    36. Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan L, Jan YN, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nat Commun. 2014 May 15; 5:3626. PMID: 24832154; PMCID: PMC4077998.
    37. Parrish JZ, Kim CC, Tang L, Bergquist S, Wang T, Derisi JL, Jan L, Jan YN, Davis GW. Krüppel mediates the selective rebalancing of ion channel expression. Neuron. 2014 May 07; 82(3):537-44. PMID: 24811378; PMCID: PMC4104505.
    38. Rumpf S, Bagley JA, Thompson-Peer KL, Zhu S, Gorczyca D, Beckstead RB, Jan L, Jan YN. Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7331-6. PMID: 24799714; PMCID: PMC4034197.
    39. Jan L. Lily Jan. Curr Biol. 2014 Mar 17; 24(6):R212-3. PMID: 24795915.
      View in: PubMed
    40. Han C, Song Y, Xiao H, Wang D, Franc NC, Jan L, Jan YN. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron. 2014 Feb 05; 81(3):544-560. PMID: 24412417; PMCID: PMC3995171.
    41. Kim WJ, Jan L, Jan YN. A PDF/NPF neuropeptide signaling circuitry of male Drosophila melanogaster controls rival-induced prolonged mating. Neuron. 2013 Dec 04; 80(5):1190-205. PMID: 24314729; PMCID: PMC3867312.
    42. Yuan Q, Song Y, Yang CH, Jan L, Jan YN. Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila. Nat Neurosci. 2014 Jan; 17(1):81-8. PMID: 24241395; PMCID: PMC3995170.
    43. Wong XM, Younger S, Peters CJ, Jan YN, Jan L. Subdued, a TMEM16 family Ca²?-activated Cl?channel in Drosophila melanogaster with an unexpected role in host defense. Elife. 2013 Nov 05; 2:e00862. PMID: 24192034; PMCID: PMC3814000.
    44. Isacoff EY, Jan L, Minor DL. Conduits of life's spark: a perspective on ion channel research since the birth of neuron. Neuron. 2013 Oct 30; 80(3):658-74. PMID: 24183018; PMCID: PMC3867263.
    45. Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan L, Guo S. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2013 Sep 10; 2:e00508. PMID: 24040509; PMCID: PMC3771564.
    46. Han TW, Jan L. Making antisense of pain. Nat Neurosci. 2013 Aug; 16(8):986-7. PMID: 23887131.
      View in: PubMed
    47. Zhang W, Yan Z, Jan L, Jan YN. Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13612-7. PMID: 23898199; PMCID: PMC3746866.
    48. Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan YN, Basbaum AI, Jan L. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci. 2013 Sep; 16(9):1284-90. PMID: 23872594; PMCID: PMC4034143.
    49. Tien J, Lee HY, Minor DL, Jan YN, Jan L. Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6352-7. PMID: 23576756; PMCID: PMC3631655.
    50. Thayer DA, Jan YN, Jan L. Increased neuronal activity fragments the Golgi complex. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1482-7. PMID: 23297202; PMCID: PMC3557034.
    51. Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y, Cheng LE, Meltzer S, Jan L, Jan YN. Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature. 2013 Jan 10; 493(7431):221-5. PMID: 23222543; PMCID: PMC3917554.
    52. Ori-McKenney KM, Jan L, Jan YN. Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons. Neuron. 2012 Dec 06; 76(5):921-30. PMID: 23217741; PMCID: PMC3523279.
    53. Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan YN, Jan L. TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell. 2012 Sep 28; 151(1):111-22. PMID: 23021219; PMCID: PMC3582364.
    54. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan L, Rock JR. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16354-9. PMID: 22988107; PMCID: PMC3479591.
    55. Yang SB, Tien AC, Boddupalli G, Xu AW, Jan YN, Jan L. Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron. 2012 Aug 09; 75(3):425-36. PMID: 22884327; PMCID: PMC3467009.
    56. Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch DH, Shuman MA, Jan YN, Jan L. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 2012 Aug 15; 26(16):1780-96. PMID: 22855790; PMCID: PMC3426758.
    57. Song Y, Ori-McKenney KM, Zheng Y, Han C, Jan L, Jan YN. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev. 2012 Jul 15; 26(14):1612-25. PMID: 22759636; PMCID: PMC3404388.
    58. Kim WJ, Jan L, Jan YN. Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. Nat Neurosci. 2012 Jun; 15(6):876-83. PMID: 22561453; PMCID: PMC3417086.
    59. Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan L. Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron. 2012 Apr 12; 74(1):179-92. PMID: 22500639; PMCID: PMC3329964.
    60. Lee HY, Jan L. Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels. Curr Opin Neurobiol. 2012 Oct; 22(5):887-94. PMID: 22483378; PMCID: PMC3393774.
    61. Ge WP, Miyawaki A, Gage FH, Jan YN, Jan L. Local generation of glia is a major astrocyte source in postnatal cortex. Nature. 2012 Mar 28; 484(7394):376-80. PMID: 22456708; PMCID: PMC3777276.
    62. Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan L, Jan YN. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 2012 Mar 22; 73(6):1127-42. PMID: 22445341; PMCID: PMC3333840.
    63. Jan L, Jan YN. Voltage-gated potassium channels and the diversity of electrical signalling. J Physiol. 2012 Jun 01; 590(11):2591-9. PMID: 22431339; PMCID: PMC3424718.
    64. Berg J, Yang H, Jan L. Ca2+-activated Cl- channels at a glance. J Cell Sci. 2012 Mar 15; 125(Pt 6):1367-71. PMID: 22526416; PMCID: PMC3336373.
    65. Yang SB, Mclemore KD, Tasic B, Luo L, Jan YN, Jan L. Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers. J Physiol. 2012 Jun 01; 590(11):2645-58. PMID: 22411008; PMCID: PMC3424722.
    66. Han C, Wang D, Soba P, Zhu S, Lin X, Jan L, Jan YN. Integrins regulate repulsion-mediated dendritic patterning of drosophila sensory neurons by restricting dendrites in a 2D space. Neuron. 2012 Jan 12; 73(1):64-78. PMID: 22243747; PMCID: PMC3269260.
    67. Zhu S, Barshow S, Wildonger J, Jan L, Jan YN. Ets transcription factor Pointed promotes the generation of intermediate neural progenitors in Drosophila larval brains. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20615-20. PMID: 22143802; PMCID: PMC3251047.
    68. Yang SB, Lee HY, Young DM, Tien AC, Rowson-Baldwin A, Shu YY, Jan YN, Jan L. Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. J Mol Med (Berl). 2012 May; 90(5):575-85. PMID: 22105852; PMCID: PMC3354320.
    69. Lee HY, Ge WP, Huang W, He Y, Wang GX, Rowson-Baldwin A, Smith SJ, Jan YN, Jan L. Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein. Neuron. 2011 Nov 17; 72(4):630-42. PMID: 22099464; PMCID: PMC3433402.
    70. Huang F, Wong X, Jan L. International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels. Pharmacol Rev. 2012 Jan; 64(1):1-15. PMID: 22090471; PMCID: PMC3250081.
    71. Lee SB, Bagley JA, Lee HY, Jan L, Jan YN. Pathogenic polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16795-800. PMID: 21930920; PMCID: PMC3189048.
    72. Yuan Q, Xiang Y, Yan Z, Han C, Jan L, Jan YN. Light-induced structural and functional plasticity in Drosophila larval visual system. Science. 2011 Sep 09; 333(6048):1458-62. PMID: 21903815; PMCID: PMC4114502.
    73. Lee RM, Ryu RH, Jeong SW, Oh SJ, Huang H, Han JS, Lee CH, Lee CJ, Jan L, Jeong SM. Isolation and Expression Profile of the Ca-Activated Chloride Channel-like Membrane Protein 6 Gene in Xenopus laevis. Lab Anim Res. 2011 Jun; 27(2):109-16. PMID: 21826170; PMCID: PMC3146003.
    74. Ouyang Y, Petritsch C, Wen H, Jan L, Jan YN, Lu B. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development. 2011 Jun; 138(11):2185-96. PMID: 21558368; PMCID: PMC3091490.
    75. Han C, Jan L, Jan YN. Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila. Proc Natl Acad Sci U S A. 2011 Jun 07; 108(23):9673-8. PMID: 21606367; PMCID: PMC3111288.
    76. Ryu RH, Oh SJ, Lee RM, Jeong SW, Jan L, Lee CH, Lee CJ, Jeong SM. Cloning and heterologous expression of new xANO2 from Xenopus laevis. Biochem Biophys Res Commun. 2011 May 20; 408(4):559-65. PMID: 21521635.
      View in: PubMed
    77. Ye B, Kim JH, Yang L, McLachlan I, Younger S, Jan L, Jan YN. Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1. J Neurosci. 2011 Mar 02; 31(9):3309-19. PMID: 21368042; PMCID: PMC3086283.
    78. Rumpf S, Lee SB, Jan L, Jan YN. Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development. 2011 Mar; 138(6):1153-60. PMID: 21343367; PMCID: PMC3042870.
    79. Xiang Y, Yuan Q, Vogt N, Looger LL, Jan L, Jan YN. Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature. 2010 Dec 16; 468(7326):921-6. PMID: 21068723; PMCID: PMC3026603.
    80. Thayer DA, Jan L. Mechanisms of distribution and targeting of neuronal ion channels. Curr Opin Drug Discov Devel. 2010 Sep; 13(5):559-67. PMID: 20812147.
      View in: PubMed
    81. Cheng LE, Song W, Looger LL, Jan L, Jan YN. The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron. 2010 Aug 12; 67(3):373-80. PMID: 20696376; PMCID: PMC2933178.
    82. Zhou W, Jan L. A twist on potassium channel gating. Cell. 2010 Jun 11; 141(6):920-2. PMID: 20550927.
      View in: PubMed
    83. Young DM, Schenk AK, Yang SB, Jan YN, Jan L. Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11074-9. PMID: 20534473; PMCID: PMC2890736.
    84. Jan YN, Jan L. Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci. 2010 May; 11(5):316-28. PMID: 20404840; PMCID: PMC3079328.
    85. Huang F, Rock JR, Harfe BD, Cheng T, Huang X, Jan YN, Jan L. Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50):21413-8. PMID: 19965375; PMCID: PMC2781737.
    86. Parrish JZ, Xu P, Kim CC, Jan L, Jan YN. The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron. 2009 Sep 24; 63(6):788-802. PMID: 19778508; PMCID: PMC2772869.
    87. Bultje RS, Castaneda-Castellanos DR, Jan L, Jan YN, Kriegstein AR, Shi SH. Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron. 2009 Jul 30; 63(2):189-202. PMID: 19640478; PMCID: PMC2736606.
    88. Lee HH, Jan L, Jan YN. Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6363-8. PMID: 19329489; PMCID: PMC2661847.
    89. Xiao S, Jan L. A gate keeper for axonal transport. Cell. 2009 Mar 20; 136(6):996-8. PMID: 19303842.
      View in: PubMed
    90. Yang CH, Rumpf S, Xiang Y, Gordon MD, Song W, Jan L, Jan YN. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 2009 Feb 26; 61(4):519-26. PMID: 19249273; PMCID: PMC2748846.
    91. Chung HJ, Ge WP, Qian X, Wiser O, Jan YN, Jan L. G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):635-40. PMID: 19118199.
      View in: PubMed
    92. Chung HJ, Qian X, Ehlers M, Jan YN, Jan L. Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):629-34. PMID: 19118198.
      View in: PubMed
    93. Ge WP, Zhou W, Luo Q, Jan L, Jan YN. Dividing glial cells maintain differentiated properties including complex morphology and functional synapses. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):328-33. PMID: 19104058.
      View in: PubMed
    94. Schroeder BC, Cheng T, Jan YN, Jan L. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell. 2008 Sep 19; 134(6):1019-29. PMID: 18805094; PMCID: PMC2651354.
    95. Wildonger J, Jan L, Jan YN. The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels. Genes Dev. 2008 Sep 15; 22(18):2447-53. PMID: 18794342; PMCID: PMC2749676.
    96. Zheng Y, Wildonger J, Ye B, Zhang Y, Kita A, Younger SH, Zimmerman S, Jan L, Jan YN. Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol. 2008 Oct; 10(10):1172-80. PMID: 18758451; PMCID: PMC2588425.
    97. Yang SB, Jan L. Thrilling moment of an inhibitory channel. Neuron. 2008 Jun 26; 58(6):823-4. PMID: 18579071.
      View in: PubMed
    98. Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan L, Tristani-Firouzi M, Stainier DY. Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol. 2008 May 13; 6(5):e109. PMID: 18479184; PMCID: PMC2430899.
    99. Yang CH, Belawat P, Hafen E, Jan L, Jan YN. Drosophila egg-laying site selection as a system to study simple decision-making processes. Science. 2008 Mar 21; 319(5870):1679-83. PMID: 18356529; PMCID: PMC2581776.
    100. Jin T, Sui JL, Rosenhouse-Dantsker A, Chan KW, Jan L, Logothetis DE. Stoichiometry of Kir channels with phosphatidylinositol bisphosphate. Channels (Austin). 2008 Jan-Feb; 2(1):19-33. PMID: 18690051.
      View in: PubMed
    101. Chi NC, Shaw RM, De Val S, Kang G, Jan L, Black BL, Stainier DY. Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev. 2008 Mar 15; 22(6):734-9. PMID: 18347092; PMCID: PMC2275426.
    102. Jan YN, Jan L. Retrospective: Seymour Benzer (1921-2007). Science. 2008 Jan 04; 319(5859):45. PMID: 18174427.
      View in: PubMed
    103. Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan L, Schuldiner M. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84. PMID: 17989219; PMCID: PMC2084299.
    104. Ye B, Zhang Y, Song W, Younger SH, Jan L, Jan YN. Growing dendrites and axons differ in their reliance on the secretory pathway. Cell. 2007 Aug 24; 130(4):717-29. PMID: 17719548; PMCID: PMC2020851.
    105. Chang W, Tu C, Cheng Z, Rodriguez L, Chen TH, Gassmann M, Bettler B, Margeta M, Jan L, Shoback D. Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. J Biol Chem. 2007 Aug 24; 282(34):25030-40. PMID: 17591780.
      View in: PubMed
    106. Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan L, Jan YN, Rakic P, Sestan N. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul; 10(7):819-27. PMID: 17589506.
      View in: PubMed
    107. Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan L, Jan YN. Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron. 2007 May 03; 54(3):403-16. PMID: 17481394; PMCID: PMC1963441.
    108. Parrish JZ, Emoto K, Jan L, Jan YN. Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes Dev. 2007 Apr 15; 21(8):956-72. PMID: 17437999; PMCID: PMC1847713.
    109. Song W, Onishi M, Jan L, Jan YN. Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5199-204. PMID: 17360325; PMCID: PMC1820883.
    110. Gong Q, Weide M, Huntsman C, Xu Z, Jan L, Ma D. Identification and characterization of a new class of trafficking motifs for controlling clathrin-independent internalization and recycling. J Biol Chem. 2007 Apr 27; 282(17):13087-97. PMID: 17331948.
      View in: PubMed
    111. Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan L. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 2007 Feb 09; 128(3):547-60. PMID: 17289573; PMCID: PMC1955433.
    112. Grueber WB, Ye B, Yang CH, Younger S, Borden K, Jan L, Jan YN. Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development. 2007 Jan; 134(1):55-64. PMID: 17164414.
      View in: PubMed
    113. Grabe M, Lai HC, Jain M, Jan YN, Jan L. Structure prediction for the down state of a potassium channel voltage sensor. Nature. 2007 Feb 01; 445(7127):550-3. PMID: 17187053.
      View in: PubMed
    114. Chung HJ, Jan L. Channeling to the nucleus. Neuron. 2006 Dec 21; 52(6):937-40. PMID: 17178398.
      View in: PubMed
    115. Kuo CT, Mirzadeh Z, Soriano-Navarro M, Rasin M, Wang D, Shen J, Sestan N, Garcia-Verdugo J, Alvarez-Buylla A, Jan L, Jan YN. Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell. 2006 Dec 15; 127(6):1253-64. PMID: 17174898; PMCID: PMC1876765.
    116. Gu C, Zhou W, Puthenveedu MA, Xu M, Jan YN, Jan L. The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron. 2006 Dec 07; 52(5):803-16. PMID: 17145502.
      View in: PubMed
    117. Fay AJ, Qian X, Jan YN, Jan L. SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17548-53. PMID: 17085590; PMCID: PMC1634413.
    118. Ja WW, Wiser O, Austin RJ, Jan L, Roberts RW. Turning G proteins on and off using peptide ligands. ACS Chem Biol. 2006 Oct 24; 1(9):570-4. PMID: 17168552; PMCID: PMC2802464.
    119. Ye B, Zhang YW, Jan L, Jan YN. The secretory pathway and neuron polarization. J Neurosci. 2006 Oct 18; 26(42):10631-2. PMID: 17050701.
      View in: PubMed
    120. Raab-Graham KF, Haddick PC, Jan YN, Jan L. Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science. 2006 Oct 06; 314(5796):144-8. PMID: 17023663.
      View in: PubMed
    121. Kim MD, Jan L, Jan YN. The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev. 2006 Oct 15; 20(20):2806-19. PMID: 17015425; PMCID: PMC1619948.
    122. Bichet D, Grabe M, Jan YN, Jan L. Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14355-60. PMID: 16983069; PMCID: PMC1570129.
    123. Grabe M, Bichet D, Qian X, Jan YN, Jan L. K+ channel selectivity depends on kinetic as well as thermodynamic factors. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14361-6. PMID: 16983068; PMCID: PMC1570128.
    124. Emoto K, Parrish JZ, Jan L, Jan YN. The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature. 2006 Sep 14; 443(7108):210-3. PMID: 16906135.
      View in: PubMed
    125. Kuo CT, Zhu S, Younger S, Jan L, Jan YN. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron. 2006 Aug 03; 51(3):283-90. PMID: 16880123.
      View in: PubMed
    126. Lai HC, Jan L. The distribution and targeting of neuronal voltage-gated ion channels. Nat Rev Neurosci. 2006 Jul; 7(7):548-62. PMID: 16791144.
      View in: PubMed
    127. Chung HJ, Jan YN, Jan L. Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A. 2006 Jun 06; 103(23):8870-5. PMID: 16735477; PMCID: PMC1472242.
    128. Wiser O, Qian X, Ehlers M, Ja WW, Roberts RW, Reuveny E, Jan YN, Jan L. Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. Neuron. 2006 May 18; 50(4):561-73. PMID: 16701207.
      View in: PubMed
    129. Parrish JZ, Kim MD, Jan L, Jan YN. Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev. 2006 Apr 01; 20(7):820-35. PMID: 16547170; PMCID: PMC1472285.
    130. Kubo Y, Adelman JP, Clapham DE, Jan L, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA. International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev. 2005 Dec; 57(4):509-26. PMID: 16382105.
      View in: PubMed
    131. Surti TS, Huang L, Jan YN, Jan L, Cooper EC. Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17828-33. PMID: 16319223; PMCID: PMC1297712.
    132. Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan YN, Jan L. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell. 2005 Oct 07; 123(1):105-18. PMID: 16213216.
      View in: PubMed
    133. Kuo CT, Jan L, Jan YN. Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42):15230-5. PMID: 16210248; PMCID: PMC1242853.
    134. Lai HC, Grabe M, Jan YN, Jan L. The S4 voltage sensor packs against the pore domain in the KAT1 voltage-gated potassium channel. Neuron. 2005 Aug 04; 47(3):395-406. PMID: 16055063.
      View in: PubMed
    135. Surti TS, Jan L. A potassium channel, the M-channel, as a therapeutic target. Curr Opin Investig Drugs. 2005 Jul; 6(7):704-11. PMID: 16044666.
      View in: PubMed
    136. Ionescu-Zanetti C, Shaw RM, Seo J, Jan YN, Jan L, Lee LP. Mammalian electrophysiology on a microfluidic platform. Proc Natl Acad Sci U S A. 2005 Jun 28; 102(26):9112-7. PMID: 15967996; PMCID: PMC1166618.
    137. Roegiers F, Jan L, Jan YN. Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell. 2005 Aug; 16(8):3480-7. PMID: 15901829; PMCID: PMC1182290.
    138. Cohen BE, Pralle A, Yao X, Swaminath G, Gandhi CS, Jan YN, Kobilka BK, Isacoff EY, Jan L. A fluorescent probe designed for studying protein conformational change. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):965-70. PMID: 15657131; PMCID: PMC545863.
    139. Huang EJ, Li H, Tang AA, Wiggins AK, Neve RL, Zhong W, Jan L, Jan YN. Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev. 2005 Jan 01; 19(1):138-51. PMID: 15598981; PMCID: PMC540232.
    140. Grabe M, Lecar H, Jan YN, Jan L. A quantitative assessment of models for voltage-dependent gating of ion channels. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17640-5. PMID: 15591352; PMCID: PMC539724.
    141. Shi SH, Cheng T, Jan L, Jan YN. APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr Biol. 2004 Nov 23; 14(22):2025-32. PMID: 15556865.
      View in: PubMed
    142. Emoto K, He Y, Ye B, Grueber WB, Adler PN, Jan L, Jan YN. Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons. Cell. 2004 Oct 15; 119(2):245-56. PMID: 15479641.
      View in: PubMed
    143. Shi SH, Cheng T, Jan L, Jan YN. The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13346-51. PMID: 15340156; PMCID: PMC516569.
    144. Shi SH, Cox DN, Wang D, Jan L, Jan YN. Control of dendrite arborization by an Ig family member, dendrite arborization and synapse maturation 1 (Dasm1). Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13341-5. PMID: 15340157; PMCID: PMC516568.
    145. Lin YF, Raab-Graham K, Jan YN, Jan L. NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7799-804. PMID: 15136749; PMCID: PMC419686.
    146. Bichet D, Lin YF, Ibarra CA, Huang CS, Yi BA, Jan YN, Jan L. Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4441-6. PMID: 15070737; PMCID: PMC384766.
    147. Moore AW, Roegiers F, Jan L, Jan YN. Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification. Genes Dev. 2004 Mar 15; 18(6):623-8. PMID: 15075290; PMCID: PMC387238.
    148. Ye B, Petritsch C, Clark IE, Gavis ER, Jan L, Jan YN. Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol. 2004 Feb 17; 14(4):314-21. PMID: 14972682.
      View in: PubMed
    149. Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan L, Jan YN. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron. 2003 Dec 18; 40(6):1105-18. PMID: 14687546.
      View in: PubMed
    150. Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan L, Karschin A, Kim D, Kuperschmidt S, Kurachi Y, Lazdunski M, Lesage F, Lester HA, McKinnon D, Nichols CG, O'Kelly I, Robbins J, Robertson GA, Rudy B, Sanguinetti M, Seino S, Stuehmer W, Tamkun MM, Vandenberg CA, Wei A, Wulff H, Wymore RS. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev. 2003 Dec; 55(4):583-6. PMID: 14657415.
      View in: PubMed
    151. Bichet D, Haass FA, Jan L. Merging functional studies with structures of inward-rectifier K(+) channels. Nat Rev Neurosci. 2003 Dec; 4(12):957-67. PMID: 14618155.
      View in: PubMed
    152. Hong Y, Ackerman L, Jan L, Jan YN. Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12712-7. PMID: 14569003; PMCID: PMC240683.
    153. Jan YN, Jan L. The control of dendrite development. Neuron. 2003 Oct 09; 40(2):229-42. PMID: 14556706.
      View in: PubMed
    154. Rothenberg ME, Rogers SL, Vale RD, Jan L, Jan YN. Drosophila pod-1 crosslinks both actin and microtubules and controls the targeting of axons. Neuron. 2003 Aug 28; 39(5):779-91. PMID: 12948445.
      View in: PubMed
    155. Gu C, Jan YN, Jan L. A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science. 2003 Aug 01; 301(5633):646-9. PMID: 12893943.
      View in: PubMed
    156. Cohen BE, Grabe M, Jan L. Answers and questions from the KvAP structures. Neuron. 2003 Jul 31; 39(3):395-400. PMID: 12895415.
      View in: PubMed
    157. Pei L, Wiser O, Slavin A, Mu D, Powers S, Jan L, Hoey T. Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7803-7. PMID: 12782791; PMCID: PMC164668.
    158. Hu K, Huang CS, Jan YN, Jan L. ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C. Neuron. 2003 May 08; 38(3):417-32. PMID: 12741989.
      View in: PubMed
    159. Justice N, Roegiers F, Jan L, Jan YN. Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage. Curr Biol. 2003 Apr 29; 13(9):778-83. PMID: 12725738.
      View in: PubMed
    160. Grueber WB, Ye B, Moore AW, Jan L, Jan YN. Dendrites of distinct classes of Drosophila sensory neurons show different capacities for homotypic repulsion. Curr Biol. 2003 Apr 15; 13(8):618-26. PMID: 12699617.
      View in: PubMed
    161. Cooper EC, Jan L. M-channels: neurological diseases, neuromodulation, and drug development. Arch Neurol. 2003 Apr; 60(4):496-500. PMID: 12707061.
      View in: PubMed
    162. Grueber WB, Jan L, Jan YN. Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. Cell. 2003 Mar 21; 112(6):805-18. PMID: 12654247.
      View in: PubMed
    163. Mu D, Chen L, Zhang X, See LH, Koch CM, Yen C, Tong JJ, Spiegel L, Nguyen KC, Servoss A, Peng Y, Pei L, Marks JR, Lowe S, Hoey T, Jan L, McCombie WR, Wigler MH, Powers S. Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell. 2003 Mar; 3(3):297-302. PMID: 12676587.
      View in: PubMed
    164. Petritsch C, Tavosanis G, Turck CW, Jan L, Jan YN. The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts. Dev Cell. 2003 Feb; 4(2):273-81. PMID: 12586070.
      View in: PubMed
    165. Shi SH, Jan L, Jan YN. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell. 2003 Jan 10; 112(1):63-75. PMID: 12526794.
      View in: PubMed
    166. Mitrovic I, Margeta-Mitrovic M, Bader S, Stoffel M, Jan L, Basbaum AI. Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):271-6. PMID: 12496346; PMCID: PMC140949.
    167. Moore AW, Jan L, Jan YN. hamlet, a binary genetic switch between single- and multiple- dendrite neuron morphology. Science. 2002 Aug 23; 297(5585):1355-8. PMID: 12193790.
      View in: PubMed
    168. Ma D, Jan L. ER transport signals and trafficking of potassium channels and receptors. Curr Opin Neurobiol. 2002 Jun; 12(3):287-92. PMID: 12049935.
      View in: PubMed
    169. Grueber WB, Jan L, Jan YN. Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development. 2002 Jun; 129(12):2867-78. PMID: 12050135.
      View in: PubMed
    170. Cohen BE, McAnaney TB, Park ES, Jan YN, Boxer SG, Jan L. Probing protein electrostatics with a synthetic fluorescent amino acid. Science. 2002 May 31; 296(5573):1700-3. PMID: 12040199.
      View in: PubMed
    171. Ma D, Zerangue N, Raab-Graham K, Fried SR, Jan YN, Jan L. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron. 2002 Feb 28; 33(5):715-29. PMID: 11879649.
      View in: PubMed
    172. Bodmer R, Jan L, Jan YN. A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos. Roux Arch Dev Biol. 1993 Aug; 202(6):371-381. PMID: 28306050.
      View in: PubMed
    173. Giniger E, Wells W, Jan L, Jan YN. Tracing neurons with a kinesin-ß-galactosidase fusion protein. Roux Arch Dev Biol. 1993 Mar; 202(2):112-122. PMID: 28305652.
      View in: PubMed
    Lily's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _