Elizabeth St Lezin, MD

Title(s)Professor, Laboratory Medicine
SchoolSchool of Medicine
Address4150 Clement St, Blg 2, Rm 245
San Francisco CA 94121
Phone415-221-4810 ext. 3680
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityBS1981Biology
    University of California, Los AngelesMD1987Medicine
    University of California, San FranciscoResidency 1990Laboratory Medicine
    University of California, San FranciscoFellow1993Laboratory Medicine
    Collapse Awards and Honors
    UCSF2016Lab Medicine Faculty Teaching

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    WHY DO METABOLIC RISK FACTORS CLUSTER WITH HYPERTENSION?
    NIH R01HL063709Sep 20, 2000 - Jul 31, 2005
    Role: Co-Principal Investigator
    GENETICS OF HYPERTENSION
    NIH K08HL002992Apr 1, 1998 - Mar 31, 2003
    Role: Co-Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Early and sustained improvement in fatigue-related quality of life following red blood cell transfusion in outpatients. Qual Life Res. 2020 Oct; 29(10):2737-2744. Bruhn R, Karafin MS, Hilton JF, Kaidarova Z, Spencer BR, Qu L, Snyder EL, Olin R, Murphy EL, St Lezin E, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS)-III Program . PMID: 32382935.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients. Transfusion. 2019 11; 59(11):3362-3370. Roubinian NH, Westlake M, St Lezin EM, Edgren G, Brambilla DJ, Lee C, Bruhn R, Cable RG, Triulzi DJ, Glynn SA, Kleinman S, Murphy EL, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) . PMID: 31602669.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. The impact of recipient factors on the lower-than-expected hemoglobin increment in transfused outpatients with hematologic diseases. Transfusion. 2019 08; 59(8):2544-2550. Karafin MS, Bruhn R, Roubinian NH, Chowdhury D, Qu L, Snyder EL, Murphy EL, Brambilla D, Cable RG, Hilton JF, St Lezin E, NHLBI Recipient Epidemiology and Donor Evaluation (REDS)-III Study . PMID: 31270827.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    4. Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients. JAMA. 2019 06 11; 321(22):2183-2192. Edgren G, Murphy EL, Brambilla DJ, Westlake M, Rostgaard K, Lee C, Cable RG, Triulzi D, Bruhn R, St Lezin EM, Erikstrup C, Ullum H, Glynn SA, Kleinman S, Hjalgrim H, Roubinian NH, NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Group . PMID: 31184739.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    5. Therapeutic impact of red blood cell transfusion on anemic outpatients: the RETRO study. Transfusion. 2019 06; 59(6):1934-1943. St Lezin E, Karafin MS, Bruhn R, Chowdhury D, Qu L, Bialkowski W, Merenda S, D'Andrea P, McCalla AL, Anderson L, Keating SM, Stone M, Snyder EL, Brambilla D, Murphy EL, Norris PJ, Hilton JF, Spencer BR, Kleinman S, Carson JL, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS)-III Program . PMID: 30882919.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat. Physiol Res. 2003; 52(3):285-9. Pravenec M, Kren V, Krenová D, Zídek V, Simáková M, Musilová A, Vorlícek J, Lezin ES, Kurtz TW. PMID: 12790759.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    7. Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension. Physiol Res. 2003; 52(6):681-8. Pravenec M, Landa V, Zídek V, Musilová A, Kazdová L, Qi N, Wang J, St Lezin E, Kurtz TW. PMID: 14640889.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    8. Genetic analysis of metabolic defects in the spontaneously hypertensive rat. Mamm Genome. 2002 May; 13(5):253-8. Pravenec M, Zídek V, Musilová A, Simáková M, Kostka V, Mlejnek P, Kren V, Krenova D, Bílá V, Míková B, Jáchymová M, Horký K, Kazdová L, St Lezin E, Kurtz TW. PMID: 12016513.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    9. Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat. J Hypertens. 2001 Jun; 19(6):1061-4. Pravenec M, Zídek V, Musilová A, Vorlícek J, Kren V, St Lezin E, Kurtz TW. PMID: 11403354.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR. Hypertension. 2001 Apr; 37(4):1147-52. Kren V, Qi N, Krenova D, Zidek V, Sladká M, Jáchymová M, Míková B, Horky K, Bonne A, Van Lith HA, Van Zutphen BF, Lau YF, Pravenec M, St Lezin E. PMID: 11304517.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    11. Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. Nat Genet. 2001 Feb; 27(2):156-8. Pravenec M, Landa V, Zidek V, Musilova A, Kren V, Kazdova L, Aitman TJ, Glazier AM, Ibrahimi A, Abumrad NA, Qi N, Wang JM, St Lezin EM, Kurtz TW. PMID: 11175782.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    12. Hypoalgesia and hyperalgesia with inherited hypertension in the rat. . 2001 Feb; 280(2):R345-54. Taylor BK, Roderick RE, St Lezin E, Basbaum AI. PMID: 11208561.
      View in: PubMed   Mentions:
    13. Genetic susceptibility to renal injury in hypertension. Exp Nephrol. 2001; 9(6):360-5. Bidani AK, Griffin KA, Churchill PC, Churchill MC, St Lezin E, Kurtz TW. PMID: 11701994.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    14. Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension. Hypertension. 2000 Jan; 35(1 Pt 2):225-30. St Lezin E, Liu W, Wang JM, Yang Y, Qi N, Kren V, Zidek V, Kurtz TW, Pravenec M. PMID: 10642302.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    15. Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat. Hypertension. 1999 Aug; 34(2):187-91. St Lezin E, Griffin KA, Picken M, Churchill MC, Churchill PC, Kurtz TW, Liu W, Wang N, Kren V, Zidek V, Pravenec M, Bidani AK. PMID: 10454439.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    16. Congenic strains for genetic analysis of hypertension and dyslipidemia in the spontaneously hypertensive rat. Transplant Proc. 1999 May; 31(3):1555-6. Pravenec M, Krenová D, Kren V, Zídek V, Simáková M, Musilová A, Bottger A, van Zutphen BF, St Lezin E, Kurtz TW. PMID: 10330997.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    17. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet. 1999 Jan; 21(1):76-83. Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J. PMID: 9916795.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansAnimalsCells
    18. Effect of chromosome 19 transfer on blood pressure in the spontaneously hypertensive rat. Hypertension. 1999 Jan; 33(1 Pt 2):256-60. St Lezin E, Zhang L, Yang Y, Wang JM, Wang N, Qi N, Steadman JS, Liu W, Kren V, Zidek V, Krenova D, Churchill PC, Churchill MC, Pravenec M. PMID: 9931113.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    19. Linkage mapping of the interleukin 1beta converting enzyme (Il1bc) and the glutamate receptor subunit KA1 (Grik4) genes to rat chromosome 8. Folia Biol (Praha). 1998; 44(3):107-9. Pravenec M, Kren V, Hope M, Wang JM, St Lezin E. PMID: 10730851.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    20. Effect of renin gene transfer on blood pressure in the spontaneously hypertensive rat. Hypertension. 1998 Jan; 31(1 Pt 2):373-7. St Lezin E, Liu W, Wang N, Wang JM, Kren V, Zidek V, Zdobinska M, Krenova D, Bottger A, van Zutphen BF, Pravenec M. PMID: 9453331.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    21. Genetic isolation of a chromosome 1 region affecting blood pressure in the spontaneously hypertensive rat. Hypertension. 1997 Oct; 30(4):854-9. St Lezin E, Liu W, Wang JM, Wang N, Kren V, Krenova D, Musilova A, Zdobinska M, Zidek V, Lau D, Pravenec M. PMID: 9336384.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer. J Clin Invest. 1997 Sep 15; 100(6):1373-82. Churchill PC, Churchill MC, Bidani AK, Griffin KA, Picken M, Pravenec M, Kren V, St Lezin E, Wang JM, Wang N, Kurtz TW. PMID: 9294102.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    23. Linkage mapping of the mixed-lineage leukemia (Mll) gene to rat chromosome 8. Mamm Genome. 1997 Aug; 8(8):625-6. Pravenec M, Wang J, Kren V, St Lezin E. PMID: 9250881.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    24. Mapping genes controlling hematocrit in the spontaneously hypertensive rat. Mamm Genome. 1997 Jun; 8(6):387-9. Pravenec M, Zidek V, Zdobinska M, Kren V, Krenova D, Bottger A, van Zutphen LF, Wang J, St Lezin E. PMID: 9166579.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    25. Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. J Clin Invest. 1997 Feb 15; 99(4):577-81. Kren V, Pravenec M, Lu S, Krenova D, Wang JM, Wang N, Merriouns T, Wong A, St Lezin E, Lau D, Szpirer C, Szpirer J, Kurtz TW. PMID: 9045857.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    26. A genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome. 1996 Feb; 7(2):117-27. Pravenec M, Gauguier D, Schott JJ, Buard J, Kren V, Bílá V, Szpirer C, Szpirer J, Wang JM, Huang H, St Lezin E, Spence MA, Flodman P, Printz M, Lathrop GM, Vergnaud G, Kurtz TW. PMID: 8835528.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    27. Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J Clin Invest. 1996 Jan 15; 97(2):522-7. St Lezin EM, Pravenec M, Wong AL, Liu W, Wang N, Lu S, Jacob HJ, Roman RJ, Stec DE, Wang JM, Reid IA, Kurtz TW. PMID: 8567976.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    28. Mapping and sequence analysis of the gene encoding the beta subunit of the epithelial sodium channel in experimental models of hypertension. J Hypertens. 1995 Nov; 13(11):1247-51. Huang H, Pravenec M, Wang JM, Kren V, St Lezin E, Szpirer C, Szpirer J, Kurtz TW. PMID: 8984121.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    29. Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension. J Biol Chem. 1995 Jul 14; 270(28):16555-60. Cover CM, Wang JM, St Lezin E, Kurtz TW, Mellon SH. PMID: 7622461.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    30. Genetic contamination of Dahl SS/Jr rats. Impact on studies of salt-sensitive hypertension. Hypertension. 1994 Jun; 23(6 Pt 1):786-90. St Lezin EM, Pravenec M, Wong A, Wang JM, Merriouns T, Newton S, Stec DE, Roman RJ, Lau D, Morris RC. PMID: 8206578.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    31. Linkage mapping of alkaline phosphatase 1, inhibin alpha subunit, and gamma-crystallin 1 on rat chromosome 9 and Na+, K(+)-ATPase alpha 2 subunit, renin, and leukocyte common antigen on rat chromosome 13. Genomics. 1994 Jan 01; 19(1):190-1. Pravenec M, St Lezin EM, Kren V, Wang JM, Kurtz TW. PMID: 8188231.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    32. The renin gene and hypertension. Semin Nephrol. 1993 Nov; 13(6):581-5. St Lezin EM, Kurtz TW. PMID: 8278692.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    33. Linkage between the RT8 alloantigen and interleukin 6 loci on the rat chromosome 4. Transplant Proc. 1993 Oct; 25(5):2777. Kren V, Pravenec M, Bila V, Svobodova D, St Lezin E, Kurtz TW. PMID: 8105577.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    34. Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nat Genet. 1993 Apr; 3(4):346-53. Cicila GT, Rapp JP, Wang JM, St Lezin E, Ng SC, Kurtz TW. PMID: 7981756.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    35. Gene mapping in experimental hypertension. J Am Soc Nephrol. 1992 Jul; 3(1):28-34. Kurtz TW, St Lezin EM. PMID: 1327257.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    36. Genetic heterogeneity and differences in glomerular hemodynamics between inbred colonies of Munich-Wistar rats. J Am Soc Nephrol. 1992 Jul; 3(1):66-72. Fenoy FJ, St Lezin E, Kurtz TW, Roman RJ. PMID: 1391710.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    37. Hypertensive strains and normotensive 'control' strains. How closely are they related? Hypertension. 1992 May; 19(5):419-24. St Lezin E, Simonet L, Pravenec M, Kurtz TW. PMID: 1568758.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    38. Assignment of rat linkage group V to chromosome 19 by single-strand conformation polymorphism analysis of somatic cell hybrids. Genomics. 1992 Feb; 12(2):350-6. Pravenec M, Simonet L, Kren V, St Lezin E, Levan G, Szpirer J, Szpirer C, Kurtz T. PMID: 1740344.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    39. Sequence analysis of the alpha 1 Na+,K(+)-ATPase gene in the Dahl salt-sensitive rat. Hypertension. 1991 Nov; 18(5):689-93. Simonet L, St Lezin E, Kurtz TW. PMID: 1657773.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
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