Sheila Keating, PhD

Title(s)Associate Professor, Laboratory Medicine
SchoolSchool of Medicine
AddressVitalant Research Institute
270 Masonic Avenue
San Francisco CA 94118
Phone415-749-6609
ORCID ORCID Icon0000-0002-8324-3694 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Institute of Child Health, University College London, London, UKPostdoctoral Fellow2007Immunobiology
    WIMM/Oxford University, Open University, Centre for Vaccinology and Tropical Med, Oxford, UKPhD2006Vaccine Immunology
    Tulane School of Public Health and Tropical Medicine, New Orleans, LAMSPH1998Tropical Medicine
    College of the Holy Cross, Worcester, MABA1995Biology
    Collapse Awards and Honors
    National University Ireland, Maynooth, County Kildare, Ireland2005Dorothy Price Medal for Immunology
    CFAR2010Women and HIV Junior Scholar Award
    CHAVI2011Young Investigator

    Collapse Overview 
    Collapse Overview
    For the past 20 years I have been studying clinical diagnostics, biomarkers of immunity and immunopathology, vaccines and therapeutics to infectious and chronic diseases. For the last three years I have been working on developing polyclonal antibody therapeutics for infectious diseases, autoimmune diseases, and protection from transplant rejection. I have done this by caputuring the ENTIRE antibody repertoire from vaccine recipients, convalescent donors or immunized humanized mice. These drugs are created quickly - A covid polyclonal antibody therapeutic was made in 3 months from the receipt of donor specimens, and this therapeutic contains over 12,500 unique and COVID-specific antibodies - providing diverse neutralizing antibodies that will be resistant to viral evasion. We are looking forward to developing the next drugs for the next difficult to treat disease requiring a multi-specific poly-valent antibody therapeutic. My research has been diverse, as the Director of the Core Immunology Laboratory, I focused on biomarker discovery using low volume, high throughput immune assays to measure cytokines, chemokines, growth factors and other biomarkers of immune response or pathology in a number of studies ranging from HIV, HCV, HBV vaccine breakthrough, Chagas, West Nile Virus, cardiovascular disease, neuropathology and many other areas. Discovering biomarkers of infection enables understanding of detection of infection, protection from pathology, and development of therapeutics that will prevent disease.
    Collapse Websites

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    Collapse Featured Publications

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2. Pathogens. 2022 Jul 19; 11(7). Mizrahi RA, Lin WY, Gras A, Niedecken AR, Wagner EK, Keating SM, Ikon N, Manickam VA, Asensio MA, Leong J, Medina-Cucurella AV, Benzie E, Carter KP, Chiang Y, Edgar RC, Leong R, Lim YW, Simons JF, Spindler MJ, Stadtmiller K, Wayham N, Büscher D, Terencio JV, Germanio CD, Chamow SM, Olson C, Pino PA, Park JG, Hicks A, Ye C, Garcia-Vilanova A, Martinez-Sobrido L, Torrelles JB, Johnson DS, Adler AS. PMID: 35890050; PMCID: PMC9320065.
      View in: PubMed   Mentions:
    2. No evidence that circulating HIV-specific immune responses contribute to persistent inflammation and immune activation in persons on long-term ART. AIDS. 2022 10 01; 36(12):1617-1628. Ward AR, Thomas AS, Stevenson EM, Huang SH, Keating SM, Gandhi RT, McMahon DK, Bosch RJ, Macatangay BJ, Cyktor JC, Eron JJ, Mellors JW, Jones RB, ACTG A5321 Team. PMID: 35730388; PMCID: PMC9444951.
      View in: PubMed   Mentions:    Fields:    
    3. Body Mass Index and Leptin Are Related to Cognitive Performance Over 10 Years in Women With and Without HIV Infection. J Clin Endocrinol Metab. 2022 02 17; 107(3):e1126-e1135. Macaluso F, Weber KM, Rubin LH, Dellinger E, Holman S, Minkoff H, Keating S, Merlin LR, Gustafson DR. PMID: 34677589; PMCID: PMC8851924.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. HIV Disease Dynamics and Markers of Inflammation and CNS Injury During Primary HIV Infection and Their Relationship to Cognitive Performance. J Acquir Immune Defic Syndr. 2022 02 01; 89(2):183-190. Longino AA, Paul R, Wang Y, Lama JR, Brandes P, Ruiz E, Correa C, Keating S, Spudich SS, Pilcher C, Vecchio A, Pasalar S, Bender Ignacio RA, Valdez R, Dasgupta S, Robertson K, Duerr A. PMID: 34629415; PMCID: PMC8752485.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size. J Infect Dis. 2021 10 13; 224(7):1209-1218. Stone M, Rosenbloom DIS, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman DD, Mellors JW, Deeks SG, Lai J, Beg S, Siliciano JD, Pagliuzza A, Chomont N, Lackman-Smith C, Ptak RG, Busch MP. PMID: 32147687; PMCID: PMC8514180.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    6. Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression. PLoS One. 2021; 16(5):e0250987. Gisslen M, Keating SM, Spudich S, Arechiga V, Stephenson S, Zetterberg H, Di Germanio C, Blennow K, Fuchs D, Hagberg L, Norris PJ, Peterson J, Shacklett BL, Yiannoutsos CT, Price RW. PMID: 33983973; PMCID: PMC8118251.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    7. Generation of recombinant hyperimmune globulins from diverse B-cell repertoires. Nat Biotechnol. 2021 08; 39(8):989-999. Keating SM, Mizrahi RA, Adams MS, Asensio MA, Benzie E, Carter KP, Chiang Y, Edgar RC, Gautam BK, Gras A, Leong J, Leong R, Lim YW, Manickam VA, Medina-Cucurella AV, Niedecken AR, Saini J, Simons JF, Spindler MJ, Stadtmiller K, Tinsley B, Wagner EK, Wayham N, Tracy L, Lundberg CV, Büscher D, Terencio JV, Roalfe L, Pearce E, Richardson H, Goldblatt D, Ramjag AT, Carrington CVF, Simmons G, Muench MO, Chamow SM, Monroe B, Olson C, Oguin TH, Lynch H, Jeanfreau R, Mosher RA, Walch MJ, Bartley CR, Ross CA, Meyer EH, Adler AS, Johnson DS. PMID: 33859400; PMCID: PMC8355030.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles. Anesthesiology. 2021 03 01; 134(3):395-404. Welsby IJ, Norris PJ, Mauermann WJ, Podgoreanu MV, Conn CM, Meade L, Cannon T, Keating SM, Silliman CC, Kehler M, Schulte PJ, Kor DJ. PMID: 33503656; PMCID: PMC8054817.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. Galectin-3 Associated with Severe Forms and Long-term Mortality in Patients with Chagas Disease. Arq Bras Cardiol. 2021 02; 116(2):248-256. Fernandes F, Moreira CHV, Oliveira LC, Souza-Basqueira M, Ianni BM, Lorenzo CD, Ramires FJA, Nastari L, Cunha-Neto E, Ribeiro AL, Lopes RD, Keating SM, Sabino EC, Mady C. PMID: 33656072; PMCID: PMC7909980.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Blood transfusion safety in the country of Georgia: collateral benefit from a national hepatitis C elimination program. Transfusion. 2020 06; 60(6):1243-1252. Bloch EM, Kipiani E, Shadaker S, Alkhazashvili M, Gvinjilia L, Kuchuloria T, Chitadze N, Keating SM, Gamkrelidze A, Turdziladze A, Getia V, Nasrullah M, Averhoff F, Izoria M, Skaggs B. PMID: 32542715; PMCID: PMC7441849.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    11. Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV. Front Integr Neurosci. 2020; 14:20. Rubin LH, Xu Y, Norris PJ, Wang X, Dastgheyb R, Fitzgerald KC, Keating SM, Kaplan RC, Maki PM, Anastos K, Springer G, Benning L, Kassaye S, Gustafson DR, Valcour VG, Williams DW. PMID: 32390808; PMCID: PMC7193823.
      View in: PubMed   Mentions: 2  
    12. Influence of sickle cell disease on susceptibility to HIV infection. PLoS One. 2020; 15(4):e0218880. Kelly S, Jacobs ES, Stone M, Keating SM, Lee TH, Chafets D, Heitman J, Dimapasoc M, Operskalski E, Hagar W, Vichinsky E, Busch MP, Norris PJ, Custer B, Recipient Epidemiology and Donor Evaluation Study (REDS-III). PMID: 32267841; PMCID: PMC7141606.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    13. Remitted depression and cognition in HIV: The role of cortisol and inflammation. Psychoneuroendocrinology. 2020 04; 114:104609. Rubin LH, Langenecker SA, Phan KL, Keating SM, Neigh GN, Weber KM, Maki PM. PMID: 32062371; PMCID: PMC7254879.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. A New Perspective on HIV Diagnostics: Reinterpretation in the Age of Early Treatment. J Clin Microbiol. 2019 Oct; 57(10). Keating SM. PMID: 31366687; PMCID: PMC6760963.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    15. Development of an international external quality assurance program for HIV-1 incidence using the Limiting Antigen Avidity assay. PLoS One. 2019; 14(9):e0222290. Keating SM, Rountree W, Grebe E, Pappas AL, Stone M, Hampton D, Todd CA, Poniewierski MS, Sanchez A, Porth CG, Denny TN, Busch MP, EQAPOL Limiting Antigen (LAg) Incidence Assay External Quality Assurance (EQA) Program. PMID: 31525218; PMCID: PMC6746377.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Brief Report: HIV Antibodies Decline During Antiretroviral Therapy but Remain Correlated With HIV DNA and HIV-Specific T-Cell Responses. J Acquir Immune Defic Syndr. 2019 08 15; 81(5):594-599. Keating SM, Jones RB, Lalama CM, Bosch RJ, McMahon D, Hampton D, Cyktor J, Eron JJ, Mellors JW, Busch MP, Gandhi RT, ACTG 5321 Team. PMID: 31045647; PMCID: PMC6625873.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    17. Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for HIV incidence surveillance. PLoS One. 2019; 14(7):e0220345. Sempa JB, Welte A, Busch MP, Hall J, Hampton D, Facente SN, Keating SM, Marson K, Parkin N, Pilcher CD, Murphy G, Grebe E, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA). PMID: 31348809; PMCID: PMC6660077.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    18. Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size. PLoS Comput Biol. 2019 04; 15(4):e1006849. Rosenbloom DIS, Bacchetti P, Stone M, Deng X, Bosch RJ, Richman DD, Siliciano JD, Mellors JW, Deeks SG, Ptak RG, Hoh R, Keating SM, Dimapasoc M, Massanella M, Lai J, Sobolewski MD, Kulpa DA, Busch MP, Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group. PMID: 30978183; PMCID: PMC6481870.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    19. Therapeutic impact of red blood cell transfusion on anemic outpatients: the RETRO study. Transfusion. 2019 06; 59(6):1934-1943. St Lezin E, Karafin MS, Bruhn R, Chowdhury D, Qu L, Bialkowski W, Merenda S, D'Andrea P, McCalla AL, Anderson L, Keating SM, Stone M, Snyder EL, Brambilla D, Murphy EL, Norris PJ, Hilton JF, Spencer BR, Kleinman S, Carson JL, NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS)-III Program. PMID: 30882919; PMCID: PMC6548575.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    20. Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients. Transfusion. 2019 04; 59(4):1223-1232. Norris PJ, Schechtman K, Inglis HC, Adelman A, Heitman JW, Vilardi R, Shah A, Roubinian NH, Danesh A, Guiltinan AM, Keating SM, Lacroix J, Cohen MJ, Spinella PC. PMID: 30882927; PMCID: PMC6450744.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Effects of blood storage age on immune, coagulation, and nitric oxide parameters in transfused patients undergoing cardiac surgery. Transfusion. 2019 04; 59(4):1209-1222. Spinella PC, Sniecinski RM, Trachtenberg F, Inglis HC, Ranganathan G, Heitman JW, Szlam F, Danesh A, Stone M, Keating SM, Levy JH, Assmann SF, Steiner ME, Doctor A, Norris PJ. PMID: 30835880; PMCID: PMC8336068.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Integration of a recent infection testing algorithm into HIV surveillance in Ireland: improving HIV knowledge to target prevention. Epidemiol Infect. 2019 01; 147:e136. Robinson E, Moran J, O'Donnell K, Hassan J, Tuite H, Ennis O, Cooney F, Nugent E, Preston L, O'Dea S, Doyle S, Keating S, Connell J, De Gascun C, Igoe D. PMID: 30869051; PMCID: PMC6518489.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Piloting and implementation of quality assessment and quality control procedures in RBC-Omics: a large multi-center study of red blood cell hemolysis during storage. Transfusion. 2019 01; 59(1):57-66. Stone M, Keating SM, Kanias T, Lanteri MC, Lebedeva M, Sinchar D, Hampton D, Jakub A, Rychka V, Brewer G, Bakkour S, Gefter N, Murcia K, Page GP, Endres-Dighe S, Bialkowski W, Fu X, Zimring J, Raife TJ, Kleinman S, Gladwin MT, Busch MP, National Heart, Lung, and Blood Institute Recipient Epidemiology Donor Evaluation Study III (REDS-II. PMID: 30566231.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    24. Intradonor reproducibility and changes in hemolytic variables during red blood cell storage: results of recall phase of the REDS-III RBC-Omics study. Transfusion. 2019 01; 59(1):79-88. Lanteri MC, Kanias T, Keating S, Stone M, Guo Y, Page GP, Brambilla DJ, Endres-Dighe SM, Mast AE, Bialkowski W, D'Andrea P, Cable RG, Spencer BR, Triulzi DJ, Murphy EL, Kleinman S, Gladwin MT, Busch MP, NHLBI Recipient Epidemiology Donor Evaluation Study (REDS)-III Program. PMID: 30408207; PMCID: PMC7007704.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    25. A single low dose of hydrocortisone enhances cognitive functioning in HIV-infected women. AIDS. 2018 09 10; 32(14):1983-1993. Rubin LH, Phan KL, Keating SM, Maki PM. PMID: 29912061; PMCID: PMC6115286.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. Comparison of Detection Limits of Fourth- and Fifth-Generation Combination HIV Antigen-Antibody, p24 Antigen, and Viral Load Assays on Diverse HIV Isolates. J Clin Microbiol. 2018 08; 56(8). Stone M, Bainbridge J, Sanchez AM, Keating SM, Pappas A, Rountree W, Todd C, Bakkour S, Manak M, Peel SA, Coombs RW, Ramos EM, Shriver MK, Contestable P, Nair SV, Wilson DH, Stengelin M, Murphy G, Hewlett I, Denny TN, Busch MP. PMID: 29793968; PMCID: PMC6062817.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    27. Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury. Trauma Surg Acute Care Open. 2018; 3(1):e000171. Hendrickson CM, Gibb SL, Miyazawa BY, Keating SM, Ross E, Conroy AS, Calfee CS, Pati S, Cohen MJ. PMID: 30023434; PMCID: PMC6045722.
      View in: PubMed   Mentions: 4  
    28. Evolution of Validated Biomarkers and Intraoperative Parameters in the Development of Postoperative ARDS. Respir Care. 2018 Nov; 63(11):1331-1340. Yadav H, Bartley A, Keating S, Meade LA, Norris PJ, Carter RE, Gajic O, Kor DJ. PMID: 29921605.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Neopterin is associated with hippocampal subfield volumes and cognition in HIV. Neurol Neuroimmunol Neuroinflamm. 2018 Jul; 5(4):e467. Fleischman DA, Arfanakis K, Leurgans S, Keating SM, Lamar M, Bennett DA, Adeyemi OM, Barnes LL. PMID: 29904644; PMCID: PMC5999345.
      View in: PubMed   Mentions: 3     Fields:    
    30. Granulocyte-Derived Extracellular Vesicles Activate Monocytes and Are Associated With Mortality in Intensive Care Unit Patients. Front Immunol. 2018; 9:956. Danesh A, Inglis HC, Abdel-Mohsen M, Deng X, Adelman A, Schechtman KB, Heitman JW, Vilardi R, Shah A, Keating SM, Cohen MJ, Jacobs ES, Pillai SK, Lacroix J, Spinella PC, Norris PJ. PMID: 29867942; PMCID: PMC5951932.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    31. Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α. Sci Transl Med. 2018 04 25; 10(438). Frascoli M, Coniglio L, Witt R, Jeanty C, Fleck-Derderian S, Myers DE, Lee TH, Keating S, Busch MP, Norris PJ, Tang Q, Cruz G, Barcellos LF, Gomez-Lopez N, Romero R, MacKenzie TC. PMID: 29695455; PMCID: PMC6449052.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    32. Computational analysis of antibody dynamics identifies recent HIV-1 infection. JCI Insight. 2017 12 21; 2(24). Seaton KE, Vandergrift NA, Deal AW, Rountree W, Bainbridge J, Grebe E, Anderson DA, Sawant S, Shen X, Yates NL, Denny TN, Liao HX, Haynes BF, Robb ML, Parkin N, Santos BR, Garrett N, Price MA, Naniche D, Duerr AC, CEPHIA group, Keating S, Hampton D, Facente S, Marson K, Welte A, Pilcher CD, Cohen MS, Tomaras GD. PMID: 29263306; PMCID: PMC5752300.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    33. Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms. J Acquir Immune Defic Syndr. 2017 12 15; 76(5):547-555. Grebe E, Welte A, Hall J, Keating SM, Facente SN, Marson K, Martin JN, Little SJ, Price MA, Kallas EG, Busch MP, Pilcher CD, Murphy G. PMID: 28914669; PMCID: PMC5680100.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsPHPublic Health
    34. Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study. PLoS Med. 2017 Nov; 14(11):e1002461. Cummins NW, Rizza S, Litzow MR, Hua S, Lee GQ, Einkauf K, Chun TW, Rhame F, Baker JV, Busch MP, Chomont N, Dean PG, Fromentin R, Haase AT, Hampton D, Keating SM, Lada SM, Lee TH, Natesampillai S, Richman DD, Schacker TW, Wietgrefe S, Yu XG, Yao JD, Zeuli J, Lichterfeld M, Badley AD. PMID: 29182633; PMCID: PMC5705162.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    35. Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study. J Neurovirol. 2018 02; 24(1):41-51. Rubin LH, Benning L, Keating SM, Norris PJ, Burke-Miller J, Savarese A, Kumanan KN, Awadalla S, Springer G, Anastos K, Young M, Milam J, Valcour VG, Weber KM, Maki PM. PMID: 29063513; PMCID: PMC6036635.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    36. The effect of HIV infection and HCV viremia on inflammatory mediators and hepatic injury-The Women's Interagency HIV Study. PLoS One. 2017; 12(9):e0181004. Keating SM, Dodge JL, Norris PJ, Heitman J, Gange SJ, French AL, Glesby MJ, Edlin BR, Latham PS, Villacres MC, Greenblatt RM, Peters MG, Women’s Interagency HIV Study. PMID: 28902848; PMCID: PMC5597129.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    37. Brief Report: Low-Dose Hydrocortisone Has Acute Enhancing Effects on Verbal Learning in HIV-Infected Men. J Acquir Immune Defic Syndr. 2017 07 01; 75(3):e65-e70. Rubin LH, Phan KL, Keating SM, Weber KM, Maki PM. PMID: 28141781; PMCID: PMC5472495.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. J Infect Dis. 2017 07 01; 216(1):72-81. Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. PMID: 28498985; PMCID: PMC5853429.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    39. Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals. J Acquir Immune Defic Syndr. 2017 07 01; 75(3):328-337. Koelsch KK, Rasmussen TA, Hey-Nguyen WJ, Pearson C, Xu Y, Bailey M, Marks KH, Sasson SC, Taylor MS, Tantau R, Obeid S, Milner B, Morrissey O, Pinto AN, Suzuki K, Busch MP, Keating SM, Kaiser P, Yukl S, Wong JK, Hiener BM, Palmer S, Zaunders J, Post JJ, Chan DJ, Avery S, Milliken ST, Kelleher AD, Lewin SR, Cooper DA. PMID: 28350553; PMCID: PMC6097982.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    40. Ethnicity, sex, and age are determinants of red blood cell storage and stress hemolysis: results of the REDS-III RBC-Omics study. Blood Adv. 2017 Jun 27; 1(15):1132-1141. Kanias T, Lanteri MC, Page GP, Guo Y, Endres SM, Stone M, Keating S, Mast AE, Cable RG, Triulzi DJ, Kiss JE, Murphy EL, Kleinman S, Busch MP, Gladwin MT. PMID: 29034365; PMCID: PMC5638435.
      View in: PubMed   Mentions: 66     Fields:    
    41. The infection staging and profile of genotypic distribution and drug resistance mutation among the human immunodeficiency virus-1 infected blood donors from five Chinese blood centers, 2012-2014. PLoS One. 2017; 12(6):e0179328. Zeng P, Liu Y, He M, Wang J, Keating S, Mao W, Huang M, Ma H, He W, Bi X, Liao D, Busch M, Ness P, Liu J, Shan H, NHLBI Recipient Epidemiology and Donor Evaluation Study-III program. PMID: 28622345; PMCID: PMC5473534.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    42. Serum from dengue virus-infected patients with and without plasma leakage differentially affects endothelial cells barrier function in vitro. PLoS One. 2017; 12(6):e0178820. Tramontini Gomes de Sousa Cardozo F, Baimukanova G, Lanteri MC, Keating SM, Moraes Ferreira F, Heitman J, Pannuti CS, Pati S, Romano CM, Cerdeira Sabino E. PMID: 28586397; PMCID: PMC5460851.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    43. Differentiating pulmonary transfusion reactions using recipient and transfusion factors. Transfusion. 2017 07; 57(7):1684-1690. Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL, TRALI Study Group. PMID: 28470756; PMCID: PMC5758383.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. Plasminogen Activator Inhibitor-1 Predicts Negative Alterations in Whole-Body Insulin Sensitivity in Chronic HIV Infection. AIDS Res Hum Retroviruses. 2017 07; 33(7):723-727. Wirunsawanya K, Belyea L, Shikuma C, Watanabe RM, Kohorn L, Shiramizu B, Mitchell BI, Souza SA, Keating SM, Norris PJ, Ndhlovu LC, Chow D. PMID: 28322572; PMCID: PMC5749045.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. The association of maternal lymphatic markers and critical congenital heart defects in the fetus-A population based case-control study. Am J Med Genet A. 2017 May; 173(5):1231-1236. Steurer MA, Norton ME, Baer RJ, Shaw GM, Keating S, Moon-Grady AJ, Chambers CD, Jelliffe-Pawlowski LL. PMID: 28323386.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression. J Virol. 2017 03 15; 91(6). Jacobs ES, Keating SM, Abdel-Mohsen M, Gibb SL, Heitman JW, Inglis HC, Martin JN, Zhang J, Kaidarova Z, Deng X, Wu S, Anastos K, Crystal H, Villacres MC, Young M, Greenblatt RM, Landay AL, Gange SJ, Deeks SG, Golub ET, Pillai SK, Norris PJ. PMID: 28053103; PMCID: PMC5331794.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    47. Comparison of cross-sectional HIV incidence assay results from dried blood spots and plasma. PLoS One. 2017; 12(2):e0172283. Schlusser KE, Pilcher C, Kallas EG, Santos BR, Deeks SG, Facente S, Keating SM, Busch MP, Murphy G, Welte A, Quinn T, Eshleman SH, Laeyendecker O. PMID: 28231277; PMCID: PMC5322916.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    48. Ghrelin, Amylin, Gastric Inhibitory Peptide and Cognition in Middle-Aged HIV-Infected and Uninfected Women: The Women's Interagency HIV Study. J Neurol Neurophysiol. 2017 Feb; 8(1). McFarlane SI, Mielke MM, Uglialoro A, Keating SM, Holman S, Minkoff H, Crystal HA, Gustafson DR. PMID: 28690913; PMCID: PMC5497768.
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    49. Moving towards a reliable HIV incidence test - current status, resources available, future directions and challenges ahead. Epidemiol Infect. 2017 04; 145(5):925-941. Murphy G, Pilcher CD, Keating SM, Kassanjee R, Facente SN, Welte A, Grebe E, Marson K, Busch MP, Dailey P, Parkin N, Osborn J, Ongarello S, Marsh K, Garcia-Calleja JM, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA). PMID: 28004622; PMCID: PMC9507805.
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    50. Performance of the Bio-Rad Geenius HIV1/2 Supplemental Assay in Detecting "Recent" HIV Infection and Calculating Population Incidence. J Acquir Immune Defic Syndr. 2016 Dec 15; 73(5):581-588. Keating SM, Kassanjee R, Lebedeva M, Facente SN, MacArthur JC, Grebe E, Murphy G, Welte A, Martin JN, Little S, Price MA, Kallas EG, Busch MP, Pilcher CD. PMID: 27509247; PMCID: PMC5110377.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    51. Brief Report: Association of Adipokines With Bone Mineral Density in HIV-Infected and HIV-Uninfected Women. J Acquir Immune Defic Syndr. 2016 Dec 01; 73(4):433-437. Sharma A, Ma Y, Scherzer R, Wheeler AL, Cohen M, Gustafson DR, Keating SM, Yin MT, Tien PC. PMID: 27792683; PMCID: PMC5098807.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates. J Virol. 2016 Nov 15; 90(22):10339-10350. Keating SM, Heitman JW, Wu S, Deng X, Stacey AR, Zahn RC, de la Rosa M, Finstad SL, Lifson JD, Piatak M, Gauduin MC, Kessler BM, Ternette N, Carville A, Johnson RP, Desrosiers RC, Letvin NL, Borrow P, Norris PJ, Schmitz JE. PMID: 27630228; PMCID: PMC5105668.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    53. High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy. Medicine (Baltimore). 2016 Oct; 95(43):e5270. Gangcuangco LMA, Kohorn LB, Chow DC, Keating SM, Norris PJ, Nagamine LS, Ndhlovu LC, Souza SA, Kallianpur KJ, Shikuma CM. PMID: 27787390; PMCID: PMC5089119.
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    54. Viral load criteria and threshold optimization to improve HIV incidence assay characteristics. AIDS. 2016 09 24; 30(15):2361-71. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA). PMID: 27454561; PMCID: PMC5024345.
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    55. Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys. J Virol. 2016 10 01; 90(19):8795-808. Himes JE, Ho C, Nguyen QN, Amos JD, Xu H, Chan C, Chow SC, Ochsenbauer C, Kaidarova Z, Keating SM, Fouda GG, Permar SR. PMID: 27466415; PMCID: PMC5021398.
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    56. Extensive Genetic Diversity of HIV-1 in Incident and Prevalent Infections among Malaysian Blood Donors: Multiple Introductions of HIV-1 Genotypes from Highly Prevalent Countries. PLoS One. 2016; 11(8):e0161853. Chow WZ, Bon AH, Keating S, Anderios F, Halim HA, Takebe Y, Kamarulzaman A, Busch MP, Tee KK. PMID: 27575746; PMCID: PMC5004849.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    57. Editorial Commentary: Timing Is Everything: Shortcomings of Current HIV Diagnostics in the Early Treatment Era. Clin Infect Dis. 2016 08 15; 63(4):562-4. Keating SM, Pilcher CD, Busch MP. PMID: 27317798.
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    58. Genetic Characterization of a Panel of Diverse HIV-1 Isolates at Seven International Sites. PLoS One. 2016; 11(6):e0157340. Hora B, Keating SM, Chen Y, Sanchez AM, Sabino E, Hunt G, Ledwaba J, Hackett J, Swanson P, Hewlett I, Ragupathy V, Vikram Vemula S, Zeng P, Tee KK, Chow WZ, Ji H, Sandstrom P, Denny TN, Busch MP, Gao F, REDS-III and EQAPOL programs. PMID: 27314585; PMCID: PMC4912073.
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    59. Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. PLoS Pathog. 2016 06; 12(6):e1005677. Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK. PMID: 27253379; PMCID: PMC4890776.
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    60. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016 06 15; 196(12):4957-66. Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC. PMID: 27183609; PMCID: PMC4977025.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    61. Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy. HIV Clin Trials. 2016 05; 17(3):114-22. Chow DC, Kagihara JM, Zhang G, Souza SA, Hodis HN, Li Y, Mitchell BI, Nakamoto BK, Kallianpur KJ, Keating SM, Norris PJ, Kohorn LB, Ndhlovu LC, Shikuma CM. PMID: 27125366; PMCID: PMC4892178.
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    62. The effects of 22°C and 4°C storage of platelets on vascular endothelial integrity and function. Transfusion. 2016 Mar; 56 Suppl 1:S52-64. Baimukanova G, Miyazawa B, Potter DR, Gibb SL, Keating S, Danesh A, Beyer A, Dayter Y, Bruhn R, Muench MO, Cap AP, Norris PJ, Spinella P, Cohen M, Pati S. PMID: 27001362.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    63. Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy. PLoS One. 2016; 11(2):e0149143. Zungsontiporn N, Tello RR, Zhang G, Mitchell BI, Budoff M, Kallianpur KJ, Nakamoto BK, Keating SM, Norris PJ, Ndhlovu LC, Souza SA, Shikuma CM, Chow DC. PMID: 26867220; PMCID: PMC4750941.
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    64. Systemic Cytokine Levels Do Not Predict CD4(+) T-Cell Recovery After Suppressive Combination Antiretroviral Therapy in Chronic Human Immunodeficiency Virus Infection. Open Forum Infect Dis. 2016 Jan; 3(1):ofw025. Norris PJ, Zhang J, Worlock A, Nair SV, Anastos K, Minkoff HL, Villacres MC, Young M, Greenblatt RM, Desai S, Landay AL, Gange SJ, Nugent CT, Golub ET, Keating SM. PMID: 26966697; PMCID: PMC4782066.
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    65. Soluble CD163 But Not Soluble CD14 Is Associated With Cytomegalovirus Immunoglobulin G Antibody Levels in Virologically Suppressed HIV+ Individuals. J Acquir Immune Defic Syndr. 2015 Dec 15; 70(5):e171-4. Hodowanec A, Williams B, Hanson B, Livak B, Keating S, Lurain N, Adeyemi OM. PMID: 26569178.
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    66. Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis. Cell Rep. 2015 Dec 22; 13(11):2553-2564. Jin J, Liss NM, Chen DH, Liao M, Fox JM, Shimak RM, Fong RH, Chafets D, Bakkour S, Keating S, Fomin ME, Muench MO, Sherman MB, Doranz BJ, Diamond MS, Simmons G. PMID: 26686638; PMCID: PMC4720387.
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    67. Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy. HIV Clin Trials. 2015 11; 16(6):228-35. Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC. PMID: 26777795; PMCID: PMC4786469.
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    68. Short Communication: SCD14 and SCD163 Levels Are Correlated with VACS Index Scores: Initial Data from the Blunted Immune Recovery in CORE Patients with HIV (BIRCH) Cohort. AIDS Res Hum Retroviruses. 2016 Feb; 32(2):144-7. Williams B, Livak B, Bahk M, Keating SM, Adeyemi OM. PMID: 26366931.
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    69. Inflammatory and cardiac biomarkers are differentially expressed in clinical stages of Chagas disease. Int J Cardiol. 2015 Nov 15; 199:451-9. Keating SM, Deng X, Fernandes F, Cunha-Neto E, Ribeiro AL, Adesina B, Beyer AI, Contestable P, Custer B, Busch MP, Sabino EC, NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component. PMID: 26277551; PMCID: PMC4868386.
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    70. Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock. J Trauma Acute Care Surg. 2015 Jun; 78(6 Suppl 1):S7-S17. Potter DR, Baimukanova G, Keating SM, Deng X, Chu JA, Gibb SL, Peng Z, Muench MO, Fomin ME, Spinella PC, Kozar R, Pati S. PMID: 26002267.
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    71. Effect of integrating HIV and addiction care for non-engaging HIV-infected opiate-dependent patients. Ir J Med Sci. 2016 Aug; 185(3):623-628. Kinahan JC, Surah S, Keating S, Bergin C, Mulcahy F, Lyons F, Keenan E. PMID: 26026954.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    72. Brain alterations within the first 100 days of HIV infection. Ann Clin Transl Neurol. 2015 Jan; 2(1):12-21. Ragin AB, Wu Y, Gao Y, Keating S, Du H, Sammet C, Kettering CS, Epstein LG. PMID: 25642430; PMCID: PMC4301670.
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    73. Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy. AIDS Res Hum Retroviruses. 2014 Dec; 30(12):1185-91. O-charoen P, Ndhlovu LC, Gangcuangco LM, Keating SM, Norris PJ, Ng RC, Mitchell BI, Shikuma CM, Chow DC. PMID: 25205472; PMCID: PMC4250959.
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    74. Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients. J Infect Dis. 2015 May 15; 211(10):1585-96. Lanteri MC, Vahidnia F, Tan S, Stapleton JT, Norris PJ, Heitman J, Deng X, Keating SM, Brambilla D, Busch MP, Custer B, NHLBI REDS III Study. PMID: 25425697; PMCID: PMC4481614.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsCTClinical Trials
    75. Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository. AIDS. 2014 Oct 23; 28(16):2439-49. Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, Martin JN, Little S, Hecht FM, Kallas EG, Welte A, Busch MP, Murphy G, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA). PMID: 25144218; PMCID: PMC4210690.
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    76. Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases. Ann Intern Med. 2014 Sep 02; 161(5):319-27. Henrich TJ, Hanhauser E, Marty FM, Sirignano MN, Keating S, Lee TH, Robles YP, Davis BT, Li JZ, Heisey A, Hill AL, Busch MP, Armand P, Soiffer RJ, Altfeld M, Kuritzkes DR. PMID: 25047577; PMCID: PMC4236912.
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    77. Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. PLoS One. 2014; 9(2):e90330. Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD. PMID: 24587328; PMCID: PMC3937368.
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    78. Development of a contemporary globally diverse HIV viral panel by the EQAPOL program. J Immunol Methods. 2014 Jul; 409:117-30. Sanchez AM, DeMarco CT, Hora B, Keinonen S, Chen Y, Brinkley C, Stone M, Tobler L, Keating S, Schito M, Busch MP, Gao F, Denny TN. PMID: 24447533; PMCID: PMC4104154.
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    79. Performance of rapid point-of-care and laboratory tests for acute and established HIV infection in San Francisco. PLoS One. 2013; 8(12):e80629. Pilcher CD, Louie B, Facente S, Keating S, Hackett J, Vallari A, Hall C, Dowling T, Busch MP, Klausner JD, Hecht FM, Liska S, Pandori MW. PMID: 24349007; PMCID: PMC3861178.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    80. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. Atherosclerosis. 2014 Jan; 232(1):52-8. Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM. PMID: 24401216; PMCID: PMC3919042.
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    81. Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors. J Infect Dis. 2014 Mar; 209(6):845-54. Keating SM, Heitman JD, Wu S, Deng X, Stramer SL, Kuhns MC, Mullen C, Norris PJ, Busch MP. PMID: 24158960; PMCID: PMC4817642.
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    82. Inter-laboratory assessment of a prototype multiplex kit for determination of recent HIV-1 infection. PLoS One. 2013; 8(10):e77765. Curtis KA, Longosz AF, Kennedy MS, Keating S, Heitman J, Laeyendecker O, Owen SM. PMID: 24147075; PMCID: PMC3798393.
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    83. IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease. PLoS One. 2013; 8(9):e75500. Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD. PMID: 24086545; PMCID: PMC3783392.
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    84. Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-α levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors. AIDS Res Hum Retroviruses. 2014 Feb; 30(2):142-6. Shikuma CM, Barbour JD, Ndhlovu LC, Keating SM, Norris PJ, Budoff M, Parikh N, Seto T, Gangcuangco LM, Ogata-Arakaki D, Chow D. PMID: 23984974; PMCID: PMC3910454.
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    85. Matrix metalloproteinase levels in early HIV infection and relation to in vivo brain status. J Neurovirol. 2013 Oct; 19(5):452-60. Li S, Wu Y, Keating SM, Du H, Sammet CL, Zadikoff C, Mahadevia R, Epstein LG, Ragin AB. PMID: 23979706; PMCID: PMC3819028.
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    86. Health-related quality of life of HIV-infected intravenous drug users. Int J STD AIDS. 2013 Nov; 24(11):867-74. Surah S, Adams R, Townsend L, Reynolds I, Kinahan JC, Keating S, Mulcahy F, Keenan E, Barry M, Lyons F. PMID: 23970601.
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    87. HIV genotypes and primary drug resistance among HIV-seropositive blood donors in Brazil: role of infected blood donors as sentinel populations for molecular surveillance of HIV. J Acquir Immune Defic Syndr. 2013 Jul 01; 63(3):387-92. Alencar CS, Sabino EC, Carvalho SM, Leao SC, Carneiro-Proietti AB, Capuani L, Oliveira CL, Carrick D, Birch RJ, Gonçalez TT, Keating S, Swanson PA, Hackett J, Busch MP, NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component. PMID: 23507660; PMCID: PMC4136640.
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    88. Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia. Pediatr Res. 2013 Sep; 74(3):290-8. Fleck S, Bautista G, Keating SM, Lee TH, Keller RL, Moon-Grady AJ, Gonzales K, Norris PJ, Busch MP, Kim CJ, Romero R, Lee H, Miniati D, MacKenzie TC. PMID: 23770923; PMCID: PMC4164304.
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    89. Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 2013; 9(5):e1003347. Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG. PMID: 23671416; PMCID: PMC3649997.
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    90. Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation. J Infect Dis. 2013 Jun 01; 207(11):1694-702. Henrich TJ, Hu Z, Li JZ, Sciaranghella G, Busch MP, Keating SM, Gallien S, Lin NH, Giguel FF, Lavoie L, Ho VT, Armand P, Soiffer RJ, Sagar M, Lacasce AS, Kuritzkes DR. PMID: 23460751; PMCID: PMC3636784.
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    91. CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis. PLoS One. 2013; 8(2):e52144. Batista MD, Tincati C, Milush JM, Ho EL, Ndhlovu LC, York VA, Kallas EG, Kalil J, Keating SM, Norris PJ, Chang D, Unemori P, Leslie KS, Maurer T, Liao W, Nixon DF. PMID: 23468834; PMCID: PMC3585296.
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    92. Lower-sensitivity and avidity modifications of the vitros anti-HIV 1+2 assay for detection of recent HIV infections and incidence estimation. J Clin Microbiol. 2012 Dec; 50(12):3968-76. Keating SM, Hanson D, Lebedeva M, Laeyendecker O, Ali-Napo NL, Owen SM, Stramer SL, Moore RD, Norris PJ, Busch MP. PMID: 23035182; PMCID: PMC3503010.
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    93. Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development. Cytokine Growth Factor Rev. 2012 Aug-Oct; 23(4-5):193-206. Keating SM, Jacobs ES, Norris PJ. PMID: 22743035; PMCID: PMC3418433.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    94. Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection. J Gen Virol. 2012 Aug; 93(Pt 8):1673-1679. Selvarajah S, Keating S, Heitman J, Lu K, Simmons G, Norris PJ, Operskalski E, Mosley JW, Busch MP. PMID: 22535775; PMCID: PMC3541758.
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    95. Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity. Blood. 2012 Jan 19; 119(3):745-55. Eriksson EM, Milush JM, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF. PMID: 22134167; PMCID: PMC3265199.
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    96. The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women. AIDS. 2011 Sep 24; 25(15):1823-32. Keating SM, Golub ET, Nowicki M, Young M, Anastos K, Crystal H, Cohen MH, Zhang J, Greenblatt RM, Desai S, Wu S, Landay AL, Gange SJ, Norris PJ, Women's Interagency HIV Study. PMID: 21572306; PMCID: PMC3314300.
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    97. Seroconverting blood donors as a resource for characterising and optimising recent infection testing algorithms for incidence estimation. PLoS One. 2011; 6(6):e20027. Kassanjee R, Welte A, McWalter TA, Keating SM, Vermeulen M, Stramer SL, Busch MP. PMID: 21694760; PMCID: PMC3111407.
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    98. Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Sci Transl Med. 2011 May 04; 3(81):81ra36. Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, Hudgens MG, Gilbert PB, Buzby AP, Mach LV, Zhang J, Balachandran H, Shaw GM, Schmidt SD, Todd JP, Dodson A, Mascola JR, Nabel GJ. PMID: 21543722; PMCID: PMC3718279.
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    99. MIG and the regulatory cytokines IL-10 and TGF-β1 correlate with malaria vaccine immunogenicity and efficacy. PLoS One. 2010 Sep 03; 5(9):e12557. Dunachie SJ, Berthoud T, Keating SM, Hill AV, Fletcher HA. PMID: 20838432; PMCID: PMC2933226.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCTClinical Trials
    100. Circulating pneumococcal specific plasma and memory B cells in the elderly two years after pneumococcal conjugate versus polysaccharide vaccination. Vaccine. 2010 Oct 04; 28(42):6915-22. Baxendale HE, Johnson M, Keating SM, Ashton L, Burbidge P, Woodgate S, Southern J, Miller E, Goldblatt D. PMID: 20708698.
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    101. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. J Virol. 2010 Oct; 84(19):10406-12. Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. PMID: 20686016; PMCID: PMC2937794.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    102. The early kinetics of circulating pneumococcal-specific memory B cells following pneumococcal conjugate and plain polysaccharide vaccines in the elderly. Vaccine. 2010 Jul 05; 28(30):4763-70. Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. PMID: 20471437.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsPHPublic Health
    103. The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming. Immunology. 2009 Sep; 128(1):83-91. Todryk SM, Pathan AA, Keating S, Porter DW, Berthoud T, Thompson F, Klenerman P, Hill AV. PMID: 19689738; PMCID: PMC2747141.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCellsPHPublic Health
    104. The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum. J Immunol. 2007 Sep 15; 179(6):4193-201. Bejon P, Mwacharo J, Kai O, Todryk S, Keating S, Lowe B, Lang T, Mwangi TW, Gilbert SC, Peshu N, Marsh K, Hill AV. PMID: 17785859; PMCID: PMC2658805.
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    105. A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya. PLoS Clin Trials. 2006 Oct 20; 1(6):e29. Bejon P, Mwacharo J, Kai O, Mwangi T, Milligan P, Todryk S, Keating S, Lang T, Lowe B, Gikonyo C, Molyneux C, Fegan G, Gilbert SC, Peshu N, Marsh K, Hill AV. PMID: 17053830; PMCID: PMC1617125.
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    106. A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge. Infect Immun. 2006 Oct; 74(10):5933-42. Dunachie SJ, Walther M, Epstein JE, Keating S, Berthoud T, Andrews L, Andersen RF, Bejon P, Goonetilleke N, Poulton I, Webster DP, Butcher G, Watkins K, Sinden RE, Levine GL, Richie TL, Schneider J, Kaslow D, Gilbert SC, Carucci DJ, Hill AV. PMID: 16988273; PMCID: PMC1594937.
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    107. Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals. Infect Immun. 2006 Nov; 74(11):6331-8. Bejon P, Keating S, Mwacharo J, Kai OK, Dunachie S, Walther M, Berthoud T, Lang T, Epstein J, Carucci D, Moris P, Cohen J, Gilbert SC, Peshu N, Marsh K, Hill AV. PMID: 16966412; PMCID: PMC1695504.
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    108. Alternating vector immunizations encoding pre-erythrocytic malaria antigens enhance memory responses in a malaria endemic area. Eur J Immunol. 2006 Aug; 36(8):2264-72. Bejon P, Kai OK, Mwacharo J, Keating S, Lang T, Gilbert SC, Peshu N, Marsh K, Hill AV. PMID: 16856208.
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    109. Safety and immunogenicity of the malaria candidate vaccines FP9 CS and MVA CS in adult Gambian men. Vaccine. 2006 Oct 30; 24(42-43):6526-33. Imoukhuede EB, Berthoud T, Milligan P, Bojang K, Ismaili J, Keating S, Nwakanma D, Keita S, Njie F, Sowe M, Todryk S, Laidlaw SM, Skinner MA, Lang T, Gilbert S, Greenwood BM, Hill AV. PMID: 16842888.
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    110. Safety, immunogenicity, and efficacy of prime-boost immunization with recombinant poxvirus FP9 and modified vaccinia virus Ankara encoding the full-length Plasmodium falciparum circumsporozoite protein. Infect Immun. 2006 May; 74(5):2706-16. Walther M, Thompson FM, Dunachie S, Keating S, Todryk S, Berthoud T, Andrews L, Andersen RF, Moore A, Gilbert SC, Poulton I, Dubovsky F, Tierney E, Correa S, Huntcooke A, Butcher G, Williams J, Sinden RE, Hill AV. PMID: 16622207; PMCID: PMC1459746.
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    111. Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area. Vaccine. 2006 May 29; 24(22):4709-15. Bejon P, Mwacharo J, Kai OK, Todryk S, Keating S, Lang T, Gilbert SC, Peshu N, Marsh K, Hill AV. PMID: 16621181.
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    112. A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS. Vaccine. 2006 Apr 05; 24(15):2850-9. Dunachie SJ, Walther M, Vuola JM, Webster DP, Keating SM, Berthoud T, Andrews L, Bejon P, Poulton I, Butcher G, Watkins K, Sinden RE, Leach A, Moris P, Tornieporth N, Schneider J, Dubovsky F, Tierney E, Williams J, Heppner DG, Gilbert SC, Cohen J, Hill AV. PMID: 16434127.
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    113. Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria. J Immunol. 2005 Nov 01; 175(9):5675-80. Keating SM, Bejon P, Berthoud T, Vuola JM, Todryk S, Webster DP, Dunachie SJ, Moorthy VS, McConkey SJ, Gilbert SC, Hill AV. PMID: 16237057.
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    114. Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis. Vaccine. 2006 May 22; 24(21):4554-61. Gilbert SC, Moorthy VS, Andrews L, Pathan AA, McConkey SJ, Vuola JM, Keating SM, Berthoud T, Webster D, McShane H, Hill AV. PMID: 16150517.
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    115. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc Natl Acad Sci U S A. 2005 Mar 29; 102(13):4836-41. Webster DP, Dunachie S, Vuola JM, Berthoud T, Keating S, Laidlaw SM, McConkey SJ, Poulton I, Andrews L, Andersen RF, Bejon P, Butcher G, Sinden R, Skinner MA, Gilbert SC, Hill AV. PMID: 15781866; PMCID: PMC555695.
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    116. Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720. Vaccine. 2005 Jan 04; 23(7):857-64. Walther M, Dunachie S, Keating S, Vuola JM, Berthoud T, Schmidt A, Maier C, Andrews L, Andersen RF, Gilbert S, Poulton I, Webster D, Dubovsky F, Tierney E, Sarpotdar P, Correa S, Huntcooke A, Butcher G, Williams J, Sinden RE, Thornton GB, Hill AV. PMID: 15603885.
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    117. Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers. J Immunol. 2005 Jan 01; 174(1):449-55. Vuola JM, Keating S, Webster DP, Berthoud T, Dunachie S, Gilbert SC, Hill AV. PMID: 15611270.
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    118. Hepatitis C viral clearance in an intravenous drug-using cohort in the Dublin area. Ir J Med Sci. 2005 Jan-Mar; 174(1):37-41. Keating S, Coughlan S, Connell J, Sweeney B, Keenan E. PMID: 15868888.
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    119. A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults. PLoS Med. 2004 Nov; 1(2):e33. Moorthy VS, Imoukhuede EB, Milligan P, Bojang K, Keating S, Kaye P, Pinder M, Gilbert SC, Walraven G, Greenwood BM, Hill AS. PMID: 15526058; PMCID: PMC524376.
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    120. Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nat Med. 2004 Nov; 10(11):1240-4. McShane H, Pathan AA, Sander CR, Keating SM, Gilbert SC, Huygen K, Fletcher HA, Hill AV. PMID: 15502839.
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    121. Hepatitis C among drug users: consensus guidelines on management in general practice. Ir J Med Sci. 2004 Jul-Sep; 173(3):145-50. Barry J, Bourke M, Buckley M, Coughlan B, Crowley D, Cullen W, Dooley S, Keating S, Kelleher D, Moloney J, Murray F, McCormick PA, MacMathuna P, O'Connor J, O'Grady J, O'Sullivan C, O'Sullivan P, Quinn C, Smyth B, Sweeney B, Dublin Area Hepatitis C Initiative Group. PMID: 15693384.
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    122. Phase 1 evaluation of 3 highly immunogenic prime-boost regimens, including a 12-month reboosting vaccination, for malaria vaccination in Gambian men. J Infect Dis. 2004 Jun 15; 189(12):2213-9. Moorthy VS, Imoukhuede EB, Keating S, Pinder M, Webster D, Skinner MA, Gilbert SC, Walraven G, Hill AV. PMID: 15181568.
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    123. Association of Gag-specific T lymphocyte responses during the early phase of human immunodeficiency virus type 1 infection and lower virus load set point. J Infect Dis. 2002 Oct 15; 186(8):1177-80. Patke DS, Langan SJ, Carruth LM, Keating SM, Sabundayo BP, Margolick JB, Quinn TC, Bollinger RC. PMID: 12355372.
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    124. Cross-clade T lymphocyte-mediated immunity to HIV type 1: implications for vaccine design and immunodetection assays. AIDS Res Hum Retroviruses. 2002 Sep 20; 18(14):1067-79. Keating SM, Bollinger RC, Quinn TC, Jackson JB, Carruth LM. PMID: 12396458.
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    125. Detection of benzodiazepine abuse in opiate addicts. Ir Med J. 1998 Jan-Feb; 91(1):18-9. Browne R, Sloan D, Fahy S, Keating S, Moran C, O'Connor J. PMID: 9563249.
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