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Theodore Kurtz, MD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentLaboratory Medicine
Address185 Berry Street, Suite 290
San Francisco CA 94107
Phone415-353-1979
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency 1983Clinical Pathology
    University of Michigan , Ann ArborMD1979Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    PATHOGENESIS OF SPONTANEOUS HYPERTENSION
    NIH/FIC R03TW001236Feb 9, 2001 - Jan 31, 2005
    Role: Principal Investigator
    WHY DO METABOLIC RISK FACTORS CLUSTER WITH HYPERTENSION?
    NIH/NHLBI R01HL063709Sep 20, 2000 - Jul 31, 2005
    Role: Principal Investigator
    New Experimental Models of Hypertension
    NIH/NHLBI R01HL056028Jan 1, 1997 - Jan 31, 2014
    Role: Principal Investigator
    KIDNEY SPECIFIC GENE TRANSFER IN HYPERTENSION
    NIH/NHLBI R01HL056608Aug 10, 1996 - Jul 31, 2006
    Role: Principal Investigator
    ROLE OF CHLORIDE IN SODIUM-DEPENDENT HYPERTENSION
    NIH/NHLBI R01HL037696Sep 30, 1986 - Sep 29, 1991
    Role: Principal Investigator
    GENETIC AND RECEPTOR MECHANISMS IN HYPERTENSION
    NIH/NHLBI P01HL035018Mar 1, 1986 - Dec 31, 2009
    Role: Co-Investigator
    DIETARY CHLORIDE AND SODIUM-DEPENDENT HYPERTENSION
    NIH/NHLBI K08HL001490Apr 1, 1985 - Apr 30, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kurtz T, DiCarlo SE, Pravenec M, Morris RC. Reply. J Hypertens. 2018 Mar; 36(3):703-704. PMID: 29384991.
      View in: PubMed
    2. Kurtz T, DiCarlo SE, Pravenec M, Morris RC. The pivotal role of renal vasodysfunction in salt sensitivity and the initiation of salt-induced hypertension. Curr Opin Nephrol Hypertens. 2018 03; 27(2):83-92. PMID: 29278541.
      View in: PubMed
    3. Kurtz T, DiCarlo SE, Pravenec M, Morris RC. The American Heart Association Scientific Statement on salt sensitivity of blood pressure: Prompting consideration of alternative conceptual frameworks for the pathogenesis of salt sensitivity? J Hypertens. 2017 Nov; 35(11):2214-2225. PMID: 28650918.
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    4. Kurtz T, Morris RC. What abnormalities initiate salt-induced increases in blood pressure according to the autoregulation and vasodysfunction theories for salt sensitivity? Kidney Int. 2017 Oct; 92(4):1015-1016. PMID: 28938938.
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    5. Kurtz T, DiCarlo SE, Morris RC. Response to Tautological Nature of Guyton's Theory of Blood Pressure Control. Am J Hypertens. 2017 Jul 01; 30(7):e6. PMID: 28407048.
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    6. Kurtz T, DiCarlo SE, Pravenec M, Morris RC. An Appraisal of Methods Recently Recommended for Testing Salt Sensitivity of Blood Pressure. J Am Heart Assoc. 2017 Apr 01; 6(4). PMID: 28365569.
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    7. Kurtz T, DiCarlo SE, Morris RC. Logical Issues With the Pressure Natriuresis Theory of Chronic Hypertension. Am J Hypertens. 2016 Dec 01; 29(12):1325-1331. PMID: 28637271.
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    8. Kurtz T, DiCarlo SE, Pravenec M, Schmidlin O, Tanaka M, Morris RC. An alternative hypothesis to the widely held view that renal excretion of sodium accounts for resistance to salt-induced hypertension. Kidney Int. 2016 11; 90(5):965-973. PMID: 27546606.
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    9. Morris RC, Schmidlin O, Sebastian A, Tanaka M, Kurtz T. Response to Hall. Circulation. 2016 Mar 01; 133(9):907. PMID: 27358993.
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    10. Morris RC, Schmidlin O, Sebastian A, Tanaka M, Kurtz T. Vasodysfunction That Involves Renal Vasodysfunction, Not Abnormally Increased Renal Retention of Sodium, Accounts for the Initiation of Salt-Induced Hypertension. Circulation. 2016 Mar 01; 133(9):881-93. PMID: 26927006; PMCID: PMC4778403 [Available on 03/01/17].
    11. Schneider K, Valdez J, Nguyen J, Vawter M, Galke B, Kurtz T, Chan JY. Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2). J Biol Chem. 2016 Apr 01; 291(14):7754-66. PMID: 26841864; PMCID: PMC4817199 [Available on 04/01/17].
    12. Pravenec M, Kožich V, Krijt J, Sokolová J, Zídek V, Landa V, Mlejnek P, Šilhavý J, Šimáková M, Škop V, Trnovská J, Kazdová L, Kajiya T, Wang J, Kurtz T. Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to Metabolic Syndrome. Hypertension. 2016 Feb; 67(2):335-41. PMID: 26667416.
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    13. Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz T, Sawamura T, Rakugi H. Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor. FASEB J. 2015 Aug; 29(8):3342-56. PMID: 25877213.
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    14. Kurtz T, Dominiczak AF, DiCarlo SE, Pravenec M, Morris RC. Molecular-based mechanisms of Mendelian forms of salt-dependent hypertension: questioning the prevailing theory. Hypertension. 2015 May; 65(5):932-41. PMID: 25753977.
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    15. Kurtz T, Lujan HL, DiCarlo SE. The 24 h pattern of arterial pressure in mice is determined mainly by heart rate-driven variation in cardiac output. Physiol Rep. 2014 Nov 01; 2(11). PMID: 25428952; PMCID: PMC4255824.
    16. Kurtz T. John Laragh: scientific pioneer. Am J Hypertens. 2014 Aug; 27(8):1010. PMID: 25103932.
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    17. Houštek J, Vrbacký M, Hejzlarová K, Zídek V, Landa V, Šilhavý J, Šimáková M, Mlejnek P, Kazdová L, Mikšík I, Neckár J, Papoušek F, Kolár F, Kurtz T, Pravenec M. Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction. Physiol Genomics. 2014 Sep 15; 46(18):671-8. PMID: 25073601.
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    18. Šilhavý J, Zídek V, Mlejnek P, Landa V, Šimáková M, Strnad H, Oliyarnyk O, Škop V, Kazdová L, Kurtz T, Pravenec M. Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats. PLoS One. 2014; 9(7):e101906. PMID: 25010431; PMCID: PMC4092096.
    19. Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Škop V, Oliyarnyk O, Kazdová L, Mancini M, Saar K, Schulz H, Hübner N, Kurtz T, Pravenec M. Rosuvastatin can block pro-inflammatory actions of transgenic human C-reactive protein without reducing its circulating levels. Cardiovasc Ther. 2014 Apr; 32(2):59-65. PMID: 24410968.
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    20. Woeber KA, White A, Kurtz T. Recurrent pituitary macroadenoma with increased plasma ACTH precursors that cross-react in a commonly used ACTH immunoassay. Endocr Pract. 2014 Jan; 20(1):94-6. PMID: 24126231.
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    21. Kurtz T. When blockade of the renin-angiotensin system becomes a two-edged sword. Am J Hypertens. 2013 Jun; 26(6):721-2. PMID: 23564251.
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    22. Zídek V, Mlejnek P, Simáková M, Silhavy J, Landa V, Kazdová L, Pravenec M, Kurtz T. Tissue-specific peroxisome proliferator activated receptor gamma expression and metabolic effects of telmisartan. Am J Hypertens. 2013 Jun; 26(6):829-35. PMID: 23426788.
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    23. Pravenec M, Kozich V, Krijt J, Sokolová J, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Oliyarnyk O, Kazdová L, Kurtz T. Folate deficiency is associated with oxidative stress, increased blood pressure, and insulin resistance in spontaneously hypertensive rats. Am J Hypertens. 2013 Jan; 26(1):135-40. PMID: 23382337; PMCID: PMC3626034.
    24. Takeuchi K, Yamamoto K, Ohishi M, Takeshita H, Hongyo K, Kawai T, Takeda M, Kamide K, Kurtz T, Rakugi H. Telmisartan modulates mitochondrial function in vascular smooth muscle cells. Hypertens Res. 2013 May; 36(5):433-9. PMID: 23254392.
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    25. Tomino Y, Cooper ME, Kurtz T, Shimizu Y. Experimental models of type-2 diabetic nephropathy. Exp Diabetes Res. 2012; 2012:218917. PMID: 22474417; PMCID: PMC3313567.
    26. Houštek J, Hejzlarová K, Vrbacký M, Drahota Z, Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavy J, Mikšík I, Kazdová L, Oliyarnyk O, Kurtz T, Pravenec M. Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains. Physiol Genomics. 2012 May 01; 44(9):487-94. PMID: 22414913; PMCID: PMC3426424.
    27. Kurtz T, Kajiya T. Differential pharmacology and benefit/risk of azilsartan compared to other sartans. Vasc Health Risk Manag. 2012; 8:133-43. PMID: 22399858; PMCID: PMC3295635.
    28. Kajiya T, Ho C, Wang J, Vilardi R, Kurtz T. Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker. J Hypertens. 2011 Dec; 29(12):2476-83. PMID: 21986624.
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    29. Neckár J, Šilhavy J, Zídek V, Landa V, Mlejnek P, Šimáková M, Seidman JG, Seidman C, Kazdová L, Klevstig M, Novák F, Vecka M, Papoušek F, Houštek J, Drahota Z, Kurtz T, Kolár F, Pravenec M. CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2012 Feb 01; 44(2):173-82. PMID: 22128087; PMCID: PMC3289117.
    30. Pravenec M, Kajiya T, Zídek V, Landa V, Mlejnek P, Simáková M, Silhavý J, Malínská H, Oliyarnyk O, Kazdová L, Fan J, Wang J, Kurtz T. Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome. Hypertension. 2011 Apr; 57(4):731-7. PMID: 21357282; PMCID: PMC3060762.
    31. Tocci G, Paneni F, Palano F, Sciarretta S, Ferrucci A, Kurtz T, Mancia G, Volpe M. Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and diabetes: a meta-analysis of placebo-controlled clinical trials. Am J Hypertens. 2011 May; 24(5):582-90. PMID: 21331058.
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    32. Pravenec M, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Maxová M, Kazdová L, Seidman JG, Seidman CE, Eminaga S, Gorham J, Wang J, Kurtz T. Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2011 Apr 12; 43(7):372-9. PMID: 21285283; PMCID: PMC3092332.
    33. Kurtz T. Genome-wide association studies will unlock the genetic basis of hypertension.: con side of the argument. Hypertension. 2010 Dec; 56(6):1021-5. PMID: 21060005.
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    34. Kurtz T. Chlorthalidone: don't call it "thiazide-like" anymore. Hypertension. 2010 Sep; 56(3):335-7. PMID: 20625074.
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    35. Mizuno CS, Chittiboyina AG, Shah FH, Patny A, Kurtz T, Pershadsingh HA, Speth RC, Karamyan VT, Carvalho PB, Avery MA. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. J Med Chem. 2010 Feb 11; 53(3):1076-85. PMID: 20073471.
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    36. Pravenec M, Kurtz T. Recent advances in genetics of the spontaneously hypertensive rat. Curr Hypertens Rep. 2010 Feb; 12(1):5-9. PMID: 20425152; PMCID: PMC2821617.
    37. Pi J, Leung L, Xue P, Wang W, Hou Y, Liu D, Yehuda-Shnaidman E, Lee C, Lau J, Kurtz T, Chan JY. Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J Biol Chem. 2010 Mar 19; 285(12):9292-300. PMID: 20089859; PMCID: PMC2838347.
    38. Yamamoto K, Ohishi M, Ho C, Kurtz T, Rakugi H. Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation. Hypertension. 2009 Dec; 54(6):1353-9. PMID: 19822796; PMCID: PMC4988847.
    39. Malínská H, Oliyarnyk O, Hubová M, Zídek V, Landa V, Simáková M, Mlejnek P, Kazdová L, Kurtz T, Pravenec M. Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis. Mol Cell Biochem. 2010 Feb; 335(1-2):119-25. PMID: 19756959.
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    40. Kurtz T, Klein U. Next generation multifunctional angiotensin receptor blockers. Hypertens Res. 2009 Oct; 32(10):826-34. PMID: 19713966.
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    41. Johnson MD, He L, Herman D, Wakimoto H, Wallace CA, Zidek V, Mlejnek P, Musilova A, Simakova M, Vorlicek J, Kren V, Viklicky O, Qi NR, Wang J, Seidman CE, Seidman J, Kurtz T, Aitman TJ, Pravenec M. Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat. Hypertension. 2009 Sep; 54(3):639-45. PMID: 19620519; PMCID: PMC4046892.
    42. Kurtz T. Beyond the classic angiotensin-receptor-blocker profile. Nat Clin Pract Cardiovasc Med. 2008 Jul; 5 Suppl 1:S19-26. PMID: 18580862.
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    43. Pravenec M, Churchill PC, Churchill MC, Viklicky O, Kazdova L, Aitman TJ, Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz T. Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet. 2008 Aug; 40(8):952-4. PMID: 18587397.
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    44. Kurtz T, Pravenec M. Molecule-specific effects of angiotensin II-receptor blockers independent of the renin-angiotensin system. Am J Hypertens. 2008 Aug; 21(8):852-9. PMID: 18535538.
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    45. Sugimoto K, Kazdová L, Qi NR, Hyakukoku M, Kren V, Simáková M, Zídek V, Kurtz T, Pravenec M. Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway. J Hypertens. 2008 Jun; 26(6):1209-15. PMID: 18475159.
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    46. Petretto E, Sarwar R, Grieve I, Lu H, Kumaran MK, Muckett PJ, Mangion J, Schroen B, Benson M, Punjabi PP, Prasad SK, Pennell DJ, Kiesewetter C, Tasheva ES, Corpuz LM, Webb MD, Conrad GW, Kurtz T, Kren V, Fischer J, Hubner N, Pinto YM, Pravenec M, Aitman TJ, Cook SA. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet. 2008 May; 40(5):546-52. PMID: 18443592.
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    47. Benson SC, Iguchi R, Ho CI, Yamamoto K, Kurtz T. Inhibition of cardiovascular cell proliferation by angiotensin receptor blockers: are all molecules the same? J Hypertens. 2008 May; 26(5):973-80. PMID: 18398340.
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    48. Mizuno CS, Chittiboyina AG, Kurtz T, Pershadsingh HA, Avery MA. Type 2 diabetes and oral antihyperglycemic drugs. Curr Med Chem. 2008; 15(1):61-74. PMID: 18220763.
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    49. Pravenec M, Kazdova L, Landa V, Zidek V, Mlejnek P, Simakova M, Jansa P, Forejt J, Kren V, Krenova D, Qi N, Wang JM, Chan D, Aitman TJ, Kurtz T. Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat. Hypertension. 2008 Jan; 51(1):148-53. PMID: 18071061.
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    50. Pravenec M, Hyakukoku M, Houstek J, Zidek V, Landa V, Mlejnek P, Miksik I, Dudová-Mothejzikova K, Pecina P, Vrbacky M, Drahota Z, Vojtiskova A, Mracek T, Kazdova L, Oliyarnyk O, Wang J, Ho C, Qi N, Sugimoto K, Kurtz T. Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains. Genome Res. 2007 Sep; 17(9):1319-26. PMID: 17693571; PMCID: PMC1950900.
    51. Pravenec M, Kurtz T. Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies. Hypertension. 2007 May; 49(5):941-52. PMID: 17339535.
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    52. Chittiboyina AG, Venkatraman MS, Mizuno CS, Desai PV, Patny A, Benson SC, Ho CI, Kurtz T, Pershadsingh HA, Avery MA. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARgamma agonists. J Med Chem. 2006 Jul 13; 49(14):4072-84. PMID: 16821769.
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    53. Kurtz T. New treatment strategies for patients with hypertension and insulin resistance. Am J Med. 2006 May; 119(5 Suppl 1):S24-30. PMID: 16563944.
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    54. Sugimoto K, Qi NR, Kazdová L, Pravenec M, Ogihara T, Kurtz T. Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosis. Hypertension. 2006 May; 47(5):1003-9. PMID: 16567593.
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    55. Bhagavathula N, Nerusu KC, Reddy M, Ellis CN, Chittiboyina A, Avery M, Pershadsingh HA, Kurtz T, Varani J. BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application. J Pharmacol Exp Ther. 2005 Dec; 315(3):996-1004. PMID: 16109743.
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    56. Qi NR, Wang J, Zidek V, Landa V, Mlejnek P, Kazdová L, Pravenec M, Kurtz T. A new transgenic rat model of hepatic steatosis and the metabolic syndrome. Hypertension. 2005 May; 45(5):1004-11. PMID: 15809359.
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    57. Kurtz T, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurement in humans and experimental animals: part 2: blood pressure measurement in experimental animals: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):e22-33. PMID: 15731483.
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    58. Kurtz T, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the Council on High Blood Pressure Research, Professional and Public Education Subcommittee. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):478-9. PMID: 15731487.
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    59. Hubner N, Wallace CA, Zimdahl H, Petretto E, Schulz H, Maciver F, Mueller M, Hummel O, Monti J, Zidek V, Musilova A, Kren V, Causton H, Game L, Born G, Schmidt S, Müller A, Cook SA, Kurtz T, Whittaker J, Pravenec M, Aitman TJ. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet. 2005 Mar; 37(3):243-53. PMID: 15711544.
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    60. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation. 2005 Feb 08; 111(5):697-716. PMID: 15699287.
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    61. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves JW, Hill MN, Jones DH, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans: an AHA scientific statement from the Council on High Blood Pressure Research Professional and Public Education Subcommittee. J Clin Hypertens (Greenwich). 2005 Feb; 7(2):102-9. PMID: 15722655.
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    62. Kurtz T, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurement in humans and experimental animals. Part 2: Blood pressure measurement in experimental animals: a statement for professionals from the subcommittee of professional and public education of the American Heart Association council on high blood pressure research. Hypertension. 2005 Feb; 45(2):299-310. PMID: 15611363.
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    63. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension. 2005 Jan; 45(1):142-61. PMID: 15611362.
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    64. Meyer B, Bazzi H, Zidek V, Musilova A, Pravenec M, Kurtz T, Nurnberg P, Christiano AM. A spontaneous mutation in the desmoglein 4 gene underlies hypotrichosis in a new lanceolate hair rat model. Differentiation. 2004 Dec; 72(9-10):541-7. PMID: 15617564.
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    65. Kurtz T, Pravenec M. Antidiabetic mechanisms of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists: beyond the renin-angiotensin system. J Hypertens. 2004 Dec; 22(12):2253-61. PMID: 15614015.
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    66. Venkatraman MS, Chittiboyina A, Meingassner J, Ho CI, Varani J, Ellis CN, Avery MA, Pershadsingh HA, Kurtz T, Benson SC. Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases. Arch Dermatol Res. 2004 Aug; 296(3):97-104. PMID: 15221328.
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    67. Pershadsingh HA, Kurtz T. Insulin-sensitizing effects of telmisartan: implications for treating insulin-resistant hypertension and cardiovascular disease. Diabetes Care. 2004 Apr; 27(4):1015. PMID: 15047668.
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    68. Benson SC, Pershadsingh HA, Ho CI, Chittiboyina A, Desai P, Pravenec M, Qi N, Wang J, Avery MA, Kurtz T. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May; 43(5):993-1002. PMID: 15007034.
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    69. Patel SN, Serghides L, Smith TG, Febbraio M, Silverstein RL, Kurtz T, Pravenec M, Kain KC. CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. J Infect Dis. 2004 Jan 15; 189(2):204-13. PMID: 14722884.
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    70. Bhagavathula N, Nerusu KC, Lal A, Ellis CN, Chittiboyina A, Avery MA, Ho CI, Benson SC, Pershadsingh HA, Kurtz T, Varani J. Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes. J Invest Dermatol. 2004 Jan; 122(1):130-9. PMID: 14962101.
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    71. Pravenec M, Kazdová L, Landa V, Zidek V, Mlejnek P, Jansa P, Wang J, Qi N, Kurtz T. Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat. J Biol Chem. 2003 Nov 14; 278(46):45209-15. PMID: 12944409.
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    72. Rao SP, McRae C, Lapanowski K, Churchill M, Kurtz T, Dunbar JC. Insulin mediated hemodynamic responses in spontaneous hypertensive rats (SHRs): effect of chromosome 4 gene transfer. Clin Exp Hypertens. 2003 Feb; 25(2):131-42. PMID: 12611424.
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    73. Kurtz T. False claims of blood pressure-independent protection by blockade of the renin angiotensin aldosterone system? Hypertension. 2003 Feb; 41(2):193-6. PMID: 12574079.
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    74. Pravenec M, Wallace C, Aitman TJ, Kurtz T. Gene expression profiling in hypertension research: a critical perspective. Hypertension. 2003 Jan; 41(1):3-8. PMID: 12511522.
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    75. Catanzaro DF, Kurtz T. Target organ damage in hypertension: mechanisms, prevention, and management. Am J Hypertens. 2002 Dec; 15(12):1117-8. PMID: 12460710.
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    76. Qi N, Kazdova L, Zidek V, Landa V, Kren V, Pershadsingh HA, Lezin ES, Abumrad NA, Pravenec M, Kurtz T. Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone. J Biol Chem. 2002 Dec 13; 277(50):48501-7. PMID: 12384507.
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    77. Churchill PC, Churchill MC, Griffin KA, Picken M, Webb RC, Kurtz T, Bidani AK. Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat. Kidney Int. 2002 May; 61(5):1794-800. PMID: 11967029.
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    78. Pravenec M, Zídek V, Musilová A, Simáková M, Kostka V, Mlejnek P, Kren V, Krenova D, Bílá V, Míková B, Jáchymová M, Horký K, Kazdová L, St Lezin E, Kurtz T. Genetic analysis of metabolic defects in the spontaneously hypertensive rat. Mamm Genome. 2002 May; 13(5):253-8. PMID: 12016513.
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    79. Pravenec M, Kurtz T. Genetics of Cd36 and the hypertension metabolic syndrome. Semin Nephrol. 2002 Mar; 22(2):148-53. PMID: 11891508.
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