Theodore Kurtz, MD

Title(s)Professor, Laboratory Medicine
SchoolSchool of Medicine
Address185 Berry Street, Suite 290
San Francisco CA 94107
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency 1983Clinical Pathology
    University of Michigan , Ann ArborMD1979Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    NIH/FIC R03TW001236Feb 9, 2001 - Jan 31, 2005
    Role: Principal Investigator
    NIH/NHLBI R01HL063709Sep 20, 2000 - Jul 31, 2005
    Role: Principal Investigator
    New Experimental Models of Hypertension
    NIH/NHLBI R01HL056028Jan 1, 1997 - Jan 31, 2014
    Role: Principal Investigator
    NIH/NHLBI R01HL056608Aug 10, 1996 - Jul 31, 2006
    Role: Principal Investigator
    NIH/NHLBI P01HL035018Jul 1, 1988 - Nov 30, 1996
    Role: Co-Investigator
    NIH/NHLBI R01HL037696Sep 30, 1986 - Sep 29, 1991
    Role: Principal Investigator
    NIH/NHLBI K08HL001490Apr 1, 1985 - Mar 31, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Strategies Are Needed to Prevent Salt-Induced Hypertension That Do Not Depend on Reducing Salt Intake. Am J Hypertens. 2020 02 22; 33(2):116-118. Kurtz TW, Pravenec M, Dicarlo SE. PMID: 31634913.
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    2. Development of In-Browser Simulators for Medical Education: Introduction of a Novel Software Toolchain. J Med Internet Res. 2019 07 03; 21(7):e14160. Šilar J, Polák D, Mládek A, Ježek F, Kurtz TW, DiCarlo SE, Živný J, Kofranek J. PMID: 31271154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Animal Models of Hypertension: A Scientific Statement From the American Heart Association. Hypertension. 2019 06; 73(6):e87-e120. Lerman LO, Kurtz TW, Touyz RM, Ellison DH, Chade AR, Crowley SD, Mattson DL, Mullins JJ, Osborn J, Eirin A, Reckelhoff JF, Iadecola C, Coffman TM. PMID: 30866654.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    4. Small Amounts of Inorganic Nitrate or Beetroot Provide Substantial Protection From Salt-Induced Increases in Blood Pressure. Hypertension. 2019 05; 73(5):1042-1048. Morris RC, Pravenec M, Šilhavý J, DiCarlo SE, Kurtz TW. PMID: 30917704.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Testing Computer Models Predicting Human Responses to a High-Salt Diet. Hypertension. 2018 12; 72(6):1407-1416. Kurtz TW, DiCarlo SE, Pravenec M, Ježek F, Šilar J, Kofránek J, Morris RC. PMID: 30571226.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Changing views on the common physiologic abnormality that mediates salt sensitivity and initiation of salt-induced hypertension: Japanese research underpinning the vasodysfunction theory of salt sensitivity. Hypertens Res. 2019 01; 42(1):6-18. Kurtz TW, DiCarlo SE, Pravenec M, Morris RC. PMID: 30390036.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. Functional foods for augmenting nitric oxide activity and reducing the risk for salt-induced hypertension and cardiovascular disease in Japan. J Cardiol. 2018 07; 72(1):42-49. Kurtz TW, DiCarlo SE, Pravenec M, Morris RC. PMID: 29544657.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    8. The pivotal role of renal vasodysfunction in salt sensitivity and the initiation of salt-induced hypertension. Curr Opin Nephrol Hypertens. 2018 Mar; 27(2):83-92. Kurtz TW, DiCarlo SE, Pravenec M, Morris RC. PMID: 29278541.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    9. Reply. J Hypertens. 2018 03; 36(3):703-704. Kurtz TW, DiCarlo SE, Pravenec M, Morris RC. PMID: 29384991.
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    10. The American Heart Association Scientific Statement on salt sensitivity of blood pressure: Prompting consideration of alternative conceptual frameworks for the pathogenesis of salt sensitivity? J Hypertens. 2017 11; 35(11):2214-2225. Kurtz TW, DiCarlo SE, Pravenec M, Morris RC. PMID: 28650918.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. What abnormalities initiate salt-induced increases in blood pressure according to the autoregulation and vasodysfunction theories for salt sensitivity? Kidney Int. 2017 10; 92(4):1015-1016. Kurtz TW, Morris RC. PMID: 28938938.
      View in: PubMed   Mentions:    Fields:    
    12. Response to Tautological Nature of Guyton's Theory of Blood Pressure Control. Am J Hypertens. 2017 07 01; 30(7):e6. Kurtz TW, DiCarlo SE, Morris RC. PMID: 28407048.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. An Appraisal of Methods Recently Recommended for Testing Salt Sensitivity of Blood Pressure. J Am Heart Assoc. 2017 04 01; 6(4). Kurtz TW, DiCarlo SE, Pravenec M, Morris RC. PMID: 28365569.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Effects of transgenic expression of dopamine beta hydroxylase (Dbh) gene on blood pressure in spontaneously hypertensive rats. Physiol Res. 2016 12 13; 65(6):1039-1044. Pravenec M, Landa V, Zídek V, Mlejnek P, Šilhavý J, Mir SA, Vaingankar SM, Wang J, Kurtz TW. PMID: 27959576.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Logical Issues With the Pressure Natriuresis Theory of Chronic Hypertension. Am J Hypertens. 2016 12 01; 29(12):1325-1331. Kurtz TW, DiCarlo SE, Morris RC. PMID: 28637271.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    16. An alternative hypothesis to the widely held view that renal excretion of sodium accounts for resistance to salt-induced hypertension. Kidney Int. 2016 11; 90(5):965-973. Kurtz TW, DiCarlo SE, Pravenec M, Schmidlin O, Tanaka M, Morris RC. PMID: 27546606.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    17. Vasodysfunction That Involves Renal Vasodysfunction, Not Abnormally Increased Renal Retention of Sodium, Accounts for the Initiation of Salt-Induced Hypertension. Circulation. 2016 Mar 01; 133(9):881-93. Morris RC, Schmidlin O, Sebastian A, Tanaka M, Kurtz TW. PMID: 26927006.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    18. Response to Hall. Circulation. 2016 Mar 01; 133(9):907. Morris RC, Schmidlin O, Sebastian A, Tanaka M, Kurtz TW. PMID: 27358993.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    19. Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2). J Biol Chem. 2016 Apr 01; 291(14):7754-66. Schneider K, Valdez J, Nguyen J, Vawter M, Galke B, Kurtz TW, Chan JY. PMID: 26841864.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    20. Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to Metabolic Syndrome. Hypertension. 2016 Feb; 67(2):335-41. Pravenec M, Kožich V, Krijt J, Sokolová J, Zídek V, Landa V, Mlejnek P, Šilhavý J, Šimáková M, Škop V, Trnovská J, Kazdová L, Kajiya T, Wang J, Kurtz TW. PMID: 26667416.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    21. Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor. FASEB J. 2015 Aug; 29(8):3342-56. Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T, Rakugi H. PMID: 25877213.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    22. Molecular-based mechanisms of Mendelian forms of salt-dependent hypertension: questioning the prevailing theory. Hypertension. 2015 May; 65(5):932-41. Kurtz TW, Dominiczak AF, DiCarlo SE, Pravenec M, Morris RC. PMID: 25753977.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    23. The 24 h pattern of arterial pressure in mice is determined mainly by heart rate-driven variation in cardiac output. Physiol Rep. 2014 Nov 01; 2(11). Kurtz TW, Lujan HL, DiCarlo SE. PMID: 25428952.
      View in: PubMed   Mentions: 6     Fields:    
    24. John Laragh: scientific pioneer. Am J Hypertens. 2014 Aug; 27(8):1010. Kurtz TW. PMID: 25103932.
      View in: PubMed   Mentions:    Fields:    
    25. Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction. Physiol Genomics. 2014 Sep 15; 46(18):671-8. Houštek J, Vrbacký M, Hejzlarová K, Zídek V, Landa V, Šilhavý J, Šimáková M, Mlejnek P, Kazdová L, Mikšík I, Neckár J, Papoušek F, Kolár F, Kurtz TW, Pravenec M. PMID: 25073601.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    26. Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats. PLoS One. 2014; 9(7):e101906. Šilhavý J, Zídek V, Mlejnek P, Landa V, Šimáková M, Strnad H, Oliyarnyk O, Škop V, Kazdová L, Kurtz T, Pravenec M. PMID: 25010431.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    27. Rosuvastatin can block pro-inflammatory actions of transgenic human C-reactive protein without reducing its circulating levels. Cardiovasc Ther. 2014 Apr; 32(2):59-65. Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Škop V, Oliyarnyk O, Kazdová L, Mancini M, Saar K, Schulz H, Hübner N, Kurtz TW, Pravenec M. PMID: 24410968.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Recurrent pituitary macroadenoma with increased plasma ACTH precursors that cross-react in a commonly used ACTH immunoassay. Endocr Pract. 2014 Jan; 20(1):94-6. Woeber KA, White A, Kurtz TW. PMID: 24126231.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. When blockade of the renin-angiotensin system becomes a two-edged sword. Am J Hypertens. 2013 Jun; 26(6):721-2. Kurtz TW. PMID: 23564251.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Tissue-specific peroxisome proliferator activated receptor gamma expression and metabolic effects of telmisartan. Am J Hypertens. 2013 Jun; 26(6):829-35. Zídek V, Mlejnek P, Simáková M, Silhavy J, Landa V, Kazdová L, Pravenec M, Kurtz TW. PMID: 23426788.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    31. Folate deficiency is associated with oxidative stress, increased blood pressure, and insulin resistance in spontaneously hypertensive rats. Am J Hypertens. 2013 Jan; 26(1):135-40. Pravenec M, Kozich V, Krijt J, Sokolová J, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Oliyarnyk O, Kazdová L, Kurtz TW. PMID: 23382337.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    32. Telmisartan modulates mitochondrial function in vascular smooth muscle cells. Hypertens Res. 2013 May; 36(5):433-9. Takeuchi K, Yamamoto K, Ohishi M, Takeshita H, Hongyo K, Kawai T, Takeda M, Kamide K, Kurtz TW, Rakugi H. PMID: 23254392.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    33. Experimental models of type-2 diabetic nephropathy. Exp Diabetes Res. 2012; 2012:218917. Tomino Y, Cooper ME, Kurtz TW, Shimizu Y. PMID: 22474417.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    34. Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains. Physiol Genomics. 2012 May 01; 44(9):487-94. Houštek J, Hejzlarová K, Vrbacký M, Drahota Z, Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavy J, Mikšík I, Kazdová L, Oliyarnyk O, Kurtz T, Pravenec M. PMID: 22414913.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    35. Differential pharmacology and benefit/risk of azilsartan compared to other sartans. Vasc Health Risk Manag. 2012; 8:133-43. Kurtz TW, Kajiya T. PMID: 22399858.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    36. Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker. J Hypertens. 2011 Dec; 29(12):2476-83. Kajiya T, Ho C, Wang J, Vilardi R, Kurtz TW. PMID: 21986624.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    37. CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2012 Feb 01; 44(2):173-82. Neckár J, Šilhavy J, Zídek V, Landa V, Mlejnek P, Šimáková M, Seidman JG, Seidman C, Kazdová L, Klevstig M, Novák F, Vecka M, Papoušek F, Houštek J, Drahota Z, Kurtz TW, Kolár F, Pravenec M. PMID: 22128087.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    38. Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome. Hypertension. 2011 Apr; 57(4):731-7. Pravenec M, Kajiya T, Zídek V, Landa V, Mlejnek P, Simáková M, Silhavý J, Malínská H, Oliyarnyk O, Kazdová L, Fan J, Wang J, Kurtz TW. PMID: 21357282.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    39. Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and diabetes: a meta-analysis of placebo-controlled clinical trials. Am J Hypertens. 2011 May; 24(5):582-90. Tocci G, Paneni F, Palano F, Sciarretta S, Ferrucci A, Kurtz T, Mancia G, Volpe M. PMID: 21331058.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    40. Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2011 Apr 12; 43(7):372-9. Pravenec M, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Maxová M, Kazdová L, Seidman JG, Seidman CE, Eminaga S, Gorham J, Wang J, Kurtz TW. PMID: 21285283.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    41. Genome-wide association studies will unlock the genetic basis of hypertension.: con side of the argument. Hypertension. 2010 Dec; 56(6):1021-5. Kurtz TW. PMID: 21060005.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    42. Chlorthalidone: don't call it "thiazide-like" anymore. Hypertension. 2010 Sep; 56(3):335-7. Kurtz TW. PMID: 20625074.
      View in: PubMed   Mentions: 7     Fields:    
    43. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. J Med Chem. 2010 Feb 11; 53(3):1076-85. Mizuno CS, Chittiboyina AG, Shah FH, Patny A, Kurtz TW, Pershadsingh HA, Speth RC, Karamyan VT, Carvalho PB, Avery MA. PMID: 20073471.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    44. Recent advances in genetics of the spontaneously hypertensive rat. Curr Hypertens Rep. 2010 Feb; 12(1):5-9. Pravenec M, Kurtz TW. PMID: 20425152.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    45. Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J Biol Chem. 2010 Mar 19; 285(12):9292-300. Pi J, Leung L, Xue P, Wang W, Hou Y, Liu D, Yehuda-Shnaidman E, Lee C, Lau J, Kurtz TW, Chan JY. PMID: 20089859.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    46. Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation. Hypertension. 2009 Dec; 54(6):1353-9. Yamamoto K, Ohishi M, Ho C, Kurtz TW, Rakugi H. PMID: 19822796.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    47. Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis. Mol Cell Biochem. 2010 Feb; 335(1-2):119-25. Malínská H, Oliyarnyk O, Hubová M, Zídek V, Landa V, Simáková M, Mlejnek P, Kazdová L, Kurtz TW, Pravenec M. PMID: 19756959.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    48. Next generation multifunctional angiotensin receptor blockers. Hypertens Res. 2009 Oct; 32(10):826-34. Kurtz TW, Klein U. PMID: 19713966.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    49. Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat. Hypertension. 2009 Sep; 54(3):639-45. Johnson MD, He L, Herman D, Wakimoto H, Wallace CA, Zidek V, Mlejnek P, Musilova A, Simakova M, Vorlicek J, Kren V, Viklicky O, Qi NR, Wang J, Seidman CE, Seidman J, Kurtz TW, Aitman TJ, Pravenec M. PMID: 19620519.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    50. Long-term pioglitazone treatment enhances lipolysis in rat adipose tissue. Int J Obes (Lond). 2008 Dec; 32(12):1848-53. Pravenec M, Kazdová L, Maxová M, Zídek V, Mlejnek P, Simáková M, Kurtz TW. PMID: 18936763.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    51. Beyond the classic angiotensin-receptor-blocker profile. Nat Clin Pract Cardiovasc Med. 2008 Jul; 5 Suppl 1:S19-26. Kurtz TW. PMID: 18580862.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    52. Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet. 2008 Aug; 40(8):952-4. Pravenec M, Churchill PC, Churchill MC, Viklicky O, Kazdova L, Aitman TJ, Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz TW. PMID: 18587397.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    53. Molecule-specific effects of angiotensin II-receptor blockers independent of the renin-angiotensin system. Am J Hypertens. 2008 Aug; 21(8):852-9. Kurtz TW, Pravenec M. PMID: 18535538.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    54. Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway. J Hypertens. 2008 Jun; 26(6):1209-15. Sugimoto K, Kazdová L, Qi NR, Hyakukoku M, Kren V, Simáková M, Zídek V, Kurtz TW, Pravenec M. PMID: 18475159.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    55. Inhibition of cardiovascular cell proliferation by angiotensin receptor blockers: are all molecules the same? J Hypertens. 2008 May; 26(5):973-80. Benson SC, Iguchi R, Ho CI, Yamamoto K, Kurtz TW. PMID: 18398340.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    56. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet. 2008 May; 40(5):546-52. Petretto E, Sarwar R, Grieve I, Lu H, Kumaran MK, Muckett PJ, Mangion J, Schroen B, Benson M, Punjabi PP, Prasad SK, Pennell DJ, Kiesewetter C, Tasheva ES, Corpuz LM, Webb MD, Conrad GW, Kurtz TW, Kren V, Fischer J, Hubner N, Pinto YM, Pravenec M, Aitman TJ, Cook SA. PMID: 18443592.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimals
    57. Type 2 diabetes and oral antihyperglycemic drugs. Curr Med Chem. 2008; 15(1):61-74. Mizuno CS, Chittiboyina AG, Kurtz TW, Pershadsingh HA, Avery MA. PMID: 18220763.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    58. Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat. Hypertension. 2008 Jan; 51(1):148-53. Pravenec M, Kazdova L, Landa V, Zidek V, Mlejnek P, Simakova M, Jansa P, Forejt J, Kren V, Krenova D, Qi N, Wang JM, Chan D, Aitman TJ, Kurtz TW. PMID: 18071061.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    59. Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains. Genome Res. 2007 Sep; 17(9):1319-26. Pravenec M, Hyakukoku M, Houstek J, Zidek V, Landa V, Mlejnek P, Miksik I, Dudová-Mothejzikova K, Pecina P, Vrbacky M, Drahota Z, Vojtiskova A, Mracek T, Kazdova L, Oliyarnyk O, Wang J, Ho C, Qi N, Sugimoto K, Kurtz T. PMID: 17693571.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    60. Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies. Hypertension. 2007 May; 49(5):941-52. Pravenec M, Kurtz TW. PMID: 17339535.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    61. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARgamma agonists. J Med Chem. 2006 Jul 13; 49(14):4072-84. Chittiboyina AG, Venkatraman MS, Mizuno CS, Desai PV, Patny A, Benson SC, Ho CI, Kurtz TW, Pershadsingh HA, Avery MA. PMID: 16821769.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    62. New treatment strategies for patients with hypertension and insulin resistance. Am J Med. 2006 May; 119(5 Suppl 1):S24-30. Kurtz TW. PMID: 16563944.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    63. Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosis. Hypertension. 2006 May; 47(5):1003-9. Sugimoto K, Qi NR, Kazdová L, Pravenec M, Ogihara T, Kurtz TW. PMID: 16567593.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    64. Fat-specific transgenic expression of resistin in the spontaneously hypertensive rat impairs fatty acid re-esterification. Int J Obes (Lond). 2006 Jul; 30(7):1157-9. Pravenec M, Kazdová L, Cahová M, Landa V, Zídek V, Mlejnek P, Simáková M, Wang J, Qi N, Kurtz TW. PMID: 16432541.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    65. BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application. J Pharmacol Exp Ther. 2005 Dec; 315(3):996-1004. Bhagavathula N, Nerusu KC, Reddy M, Ellis CN, Chittiboyina A, Avery M, Pershadsingh HA, Kurtz TW, Varani J. PMID: 16109743.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    66. A new transgenic rat model of hepatic steatosis and the metabolic syndrome. Hypertension. 2005 May; 45(5):1004-11. Qi NR, Wang J, Zidek V, Landa V, Mlejnek P, Kazdová L, Pravenec M, Kurtz TW. PMID: 15809359.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    67. Treating the metabolic syndrome: telmisartan as a peroxisome proliferator-activated receptor-gamma activator. Acta Diabetol. 2005 Apr; 42 Suppl 1:S9-16. Kurtz TW. PMID: 15868121.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    68. Recommendations for blood pressure measurement in humans and experimental animals: part 2: blood pressure measurement in experimental animals: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):e22-33. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. PMID: 15731483.
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    69. Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the Council on High Blood Pressure Research, Professional and Public Education Subcommittee. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):478-9. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. PMID: 15731487.
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    70. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet. 2005 Mar; 37(3):243-53. Hubner N, Wallace CA, Zimdahl H, Petretto E, Schulz H, Maciver F, Mueller M, Hummel O, Monti J, Zidek V, Musilova A, Kren V, Causton H, Game L, Born G, Schmidt S, Müller A, Cook SA, Kurtz TW, Whittaker J, Pravenec M, Aitman TJ. PMID: 15711544.
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    71. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation. 2005 Feb 08; 111(5):697-716. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. PMID: 15699287.
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    72. Recommendations for blood pressure measurement in humans: an AHA scientific statement from the Council on High Blood Pressure Research Professional and Public Education Subcommittee. J Clin Hypertens (Greenwich). 2005 Feb; 7(2):102-9. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves JW, Hill MN, Jones DH, Kurtz T, Sheps SG, Roccella EJ. PMID: 15722655.
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    73. Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension. 2005 Jan; 45(1):142-61. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. PMID: 15611362.
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    74. Recommendations for blood pressure measurement in humans and experimental animals. Part 2: Blood pressure measurement in experimental animals: a statement for professionals from the subcommittee of professional and public education of the American Heart Association council on high blood pressure research. Hypertension. 2005 Feb; 45(2):299-310. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. PMID: 15611363.
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    75. A spontaneous mutation in the desmoglein 4 gene underlies hypotrichosis in a new lanceolate hair rat model. Differentiation. 2004 Dec; 72(9-10):541-7. Meyer B, Bazzi H, Zidek V, Musilova A, Pravenec M, Kurtz TW, Nurnberg P, Christiano AM. PMID: 15617564.
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    76. Antidiabetic mechanisms of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists: beyond the renin-angiotensin system. J Hypertens. 2004 Dec; 22(12):2253-61. Kurtz TW, Pravenec M. PMID: 15614015.
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    77. Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases. Arch Dermatol Res. 2004 Aug; 296(3):97-104. Venkatraman MS, Chittiboyina A, Meingassner J, Ho CI, Varani J, Ellis CN, Avery MA, Pershadsingh HA, Kurtz TW, Benson SC. PMID: 15221328.
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    78. Insulin-sensitizing effects of telmisartan: implications for treating insulin-resistant hypertension and cardiovascular disease. Diabetes Care. 2004 Apr; 27(4):1015. Pershadsingh HA, Kurtz TW. PMID: 15047668.
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    79. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May; 43(5):993-1002. Benson SC, Pershadsingh HA, Ho CI, Chittiboyina A, Desai P, Pravenec M, Qi N, Wang J, Avery MA, Kurtz TW. PMID: 15007034.
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    80. CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. J Infect Dis. 2004 Jan 15; 189(2):204-13. Patel SN, Serghides L, Smith TG, Febbraio M, Silverstein RL, Kurtz TW, Pravenec M, Kain KC. PMID: 14722884.
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    81. Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes. J Invest Dermatol. 2004 Jan; 122(1):130-9. Bhagavathula N, Nerusu KC, Lal A, Ellis CN, Chittiboyina A, Avery MA, Ho CI, Benson SC, Pershadsingh HA, Kurtz TW, Varani J. PMID: 14962101.
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    82. The CD36 protein functions as an immunogenic domain of the RT8 alloantigen. Eur J Immunogenet. 2003 Oct; 30(5):325-7. Mlejnek P, Kren V, Liska F, Zídek V, Landa V, Kurtz TW, Pravenec M. PMID: 14641538.
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    83. Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat. J Biol Chem. 2003 Nov 14; 278(46):45209-15. Pravenec M, Kazdová L, Landa V, Zidek V, Mlejnek P, Jansa P, Wang J, Qi N, Kurtz TW. PMID: 12944409.
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    84. False claims of blood pressure-independent protection by blockade of the renin angiotensin aldosterone system? Hypertension. 2003 Feb; 41(2):193-6. Kurtz TW. PMID: 12574079.
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    85. Insulin mediated hemodynamic responses in spontaneous hypertensive rats (SHRs): effect of chromosome 4 gene transfer. Clin Exp Hypertens. 2003 Feb; 25(2):131-42. Rao SP, McRae C, Lapanowski K, Churchill M, Kurtz TW, Dunbar JC. PMID: 12611424.
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    86. Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat. Physiol Res. 2003; 52(3):285-9. Pravenec M, Kren V, Krenová D, Zídek V, Simáková M, Musilová A, Vorlícek J, Lezin ES, Kurtz TW. PMID: 12790759.
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    87. Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension. Physiol Res. 2003; 52(6):681-8. Pravenec M, Landa V, Zídek V, Musilová A, Kazdová L, Qi N, Wang J, St Lezin E, Kurtz TW. PMID: 14640889.
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    88. Gene expression profiling in hypertension research: a critical perspective. Hypertension. 2003 Jan; 41(1):3-8. Pravenec M, Wallace C, Aitman TJ, Kurtz TW. PMID: 12511522.
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    89. Target organ damage in hypertension: mechanisms, prevention, and management. Am J Hypertens. 2002 Dec; 15(12):1117-8. Catanzaro DF, Kurtz TW. PMID: 12460710.
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    90. Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone. J Biol Chem. 2002 Dec 13; 277(50):48501-7. Qi N, Kazdova L, Zidek V, Landa V, Kren V, Pershadsingh HA, Lezin ES, Abumrad NA, Pravenec M, Kurtz TW. PMID: 12384507.
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    91. Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat. Kidney Int. 2002 May; 61(5):1794-800. Churchill PC, Churchill MC, Griffin KA, Picken M, Webb RC, Kurtz TW, Bidani AK. PMID: 11967029.
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    92. Genetic analysis of metabolic defects in the spontaneously hypertensive rat. Mamm Genome. 2002 May; 13(5):253-8. Pravenec M, Zídek V, Musilová A, Simáková M, Kostka V, Mlejnek P, Kren V, Krenova D, Bílá V, Míková B, Jáchymová M, Horký K, Kazdová L, St Lezin E, Kurtz TW. PMID: 12016513.
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    93. Genetics of Cd36 and the hypertension metabolic syndrome. Semin Nephrol. 2002 Mar; 22(2):148-53. Pravenec M, Kurtz TW. PMID: 11891508.
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    94. New frontiers in aldosterone/mineralocorticoid biology: a reemerging force in target organ damage and hypertension. Am J Hypertens. 2001 Dec; 14(12):1276-7. Kurtz TW, Catanzaro DF. PMID: 11775139.
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    95. Kidney-specific chromosome transfer in genetic hypertension: the Dahl hypothesis revisited. Kidney Int. 2001 Aug; 60(2):705-14. Churchill PC, Churchill MC, Bidani AK, Kurtz TW. PMID: 11473653.
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    96. Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat. J Hypertens. 2001 Jun; 19(6):1061-4. Pravenec M, Zídek V, Musilová A, Vorlícek J, Kren V, St Lezin E, Kurtz TW. PMID: 11403354.
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    97. Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy. J Biol Chem. 2001 Jun 29; 276(26):23661-6. Hajri T, Ibrahimi A, Coburn CT, Knapp FF, Kurtz T, Pravenec M, Abumrad NA. PMID: 11323420.
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    98. Differential salt-sensitivity in the pathogenesis of renal damage in SHR and stroke prone SHR. Am J Hypertens. 2001 Apr; 14(4 Pt 1):311-20. Griffin KA, Churchill PC, Picken M, Webb RC, Kurtz TW, Bidani AK. PMID: 11336176.
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    99. Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat. Mamm Genome. 2001 Apr; 12(4):295-8. Pravenec M, Jansa P, Kostka V, Zídek V, Kren V, Forejt J, Kurtz TW. PMID: 11309661.
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    100. Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. Nat Genet. 2001 Feb; 27(2):156-8. Pravenec M, Landa V, Zidek V, Musilova A, Kren V, Kazdova L, Aitman TJ, Glazier AM, Ibrahimi A, Abumrad NA, Qi N, Wang JM, St Lezin EM, Kurtz TW. PMID: 11175782.
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    101. Genetic susceptibility to renal injury in hypertension. Exp Nephrol. 2001; 9(6):360-5. Bidani AK, Griffin KA, Churchill PC, Churchill MC, St Lezin E, Kurtz TW. PMID: 11701994.
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    102. Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. Arch Dermatol. 2000 May; 136(5):609-16. Ellis CN, Varani J, Fisher GJ, Zeigler ME, Pershadsingh HA, Benson SC, Chi Y, Kurtz TW. PMID: 10815854.
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    103. Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor-alpha exert synergistic antiproliferative effects on human coronary artery smooth muscle cells. Mol Cell Biol Res Commun. 2000 Mar; 3(3):159-64. Benson S, Padmanabhan S, Kurtz TW, Pershadsingh HA. PMID: 10860864.
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    104. Peroxisome proliferator-activated receptor (PPAR)-gamma expression in human vascular smooth muscle cells: inhibition of growth, migration, and c-fos expression by the peroxisome proliferator-activated receptor (PPAR)-gamma activator troglitazone. Am J Hypertens. 2000 Jan; 13(1 Pt 1):74-82. Benson S, Wu J, Padmanabhan S, Kurtz TW, Pershadsingh HA. PMID: 10678274.
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    105. Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension. Hypertension. 2000 Jan; 35(1 Pt 2):225-30. St Lezin E, Liu W, Wang JM, Yang Y, Qi N, Kren V, Zidek V, Kurtz TW, Pravenec M. PMID: 10642302.
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    106. Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat. Hypertension. 1999 Aug; 34(2):187-91. St Lezin E, Griffin KA, Picken M, Churchill MC, Churchill PC, Kurtz TW, Liu W, Wang N, Kren V, Zidek V, Pravenec M, Bidani AK. PMID: 10454439.
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    107. Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension. J Clin Invest. 1999 Jun; 103(12):1651-7. Pravenec M, Zidek V, Simakova M, Kren V, Krenova D, Horky K, Jachymova M, Mikova B, Kazdova L, Aitman TJ, Churchill PC, Webb RC, Hingarh NH, Yang Y, Wang JM, Lezin EM, Kurtz TW. PMID: 10377171.
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    108. Congenic strains for genetic analysis of hypertension and dyslipidemia in the spontaneously hypertensive rat. Transplant Proc. 1999 May; 31(3):1555-6. Pravenec M, Krenová D, Kren V, Zídek V, Simáková M, Musilová A, Bottger A, van Zutphen BF, St Lezin E, Kurtz TW. PMID: 10330997.
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    109. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet. 1999 Jan; 21(1):76-83. Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J. PMID: 9916795.
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    110. The spontaneously hypertensive rat: a model to dissect cellular defects in glucose and fatty acid metabolism. Pathol Biol (Paris). 1998 Nov; 46(9):693-4. Aitman TJ, Pravenec M, Kurtz TW, Scott J. PMID: 9885819.
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    111. Transcription-modulating drugs: a new frontier in the treatment of essential hypertension. Hypertension. 1998 Sep; 32(3):380-6. Kurtz TW, Gardner DG. PMID: 9740599.
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    112. Blood pressure and survival of a chromosome 7 congenic strain bred from Dahl rats. Mamm Genome. 1997 Dec; 8(12):896-902. Cicila GT, Dukhanina OI, Kurtz TW, Walder R, Garrett MR, Dene H, Rapp JP. PMID: 9383281.
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    113. Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer. J Clin Invest. 1997 Sep 15; 100(6):1373-82. Churchill PC, Churchill MC, Bidani AK, Griffin KA, Picken M, Pravenec M, Kren V, St Lezin E, Wang JM, Wang N, Kurtz TW. PMID: 9294102.
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    114. Rat chromosome 1: regional localization of seven genes (Slc9a3, Srd5a1, Esr, Tcp1, Grik5, Tnnt3, Jak2) and anchoring of the genetic linkage map to the cytogenetic map. Mamm Genome. 1997 Sep; 8(9):657-60. Szpirer C, Szpirer J, Tissir F, Stephanova E, Vanvooren P, Kurtz TW, Iwai N, Inagami T, Pravenec M, Kren V, Klinga-Levan K, Levan G. PMID: 9271667.
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    115. Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats. Nat Genet. 1997 Jun; 16(2):197-201. Aitman TJ, Gotoda T, Evans AL, Imrie H, Heath KE, Trembling PM, Truman H, Wallace CA, Rahman A, Doré C, Flint J, Kren V, Zidek V, Kurtz TW, Pravenec M, Scott J. PMID: 9171835.
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    116. Linkage mapping of the cellular retinoic acid-binding protein 1 (Crabp1) gene to rat chromosome 8. Mamm Genome. 1997 Jun; 8(6):455-6. Pravenec M, Kren V, Wang J, Kurtz TW. PMID: 9166599.
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    117. Map of the differential segment of rat chromosome 8 in the SHR-Lx congenic strain. Transplant Proc. 1997 May; 29(3):1769. Krenová D, Kurtz TW, Wang JM, Pravenec M, Kren V. PMID: 9142266.
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    118. Linkage mapping of the Na-K-2Cl cotransporter gene (Slc12a1) to rat chromosome 3. Mamm Genome. 1997 May; 8(5):379. Wang J, Pravenec M, Kren V, Kurtz TW. PMID: 9107691.
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    119. Rat genome mapping using recombinant inbred strains. Transplant Proc. 1997 May; 29(3):1768. Kren V, Kurtz TW, Krenova D, Bila V, Printz M, Pravenec M. PMID: 9142265.
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    120. Effects of thiazolidinediones on growth and differentiation of human aorta and coronary myocytes. Am J Hypertens. 1997 Apr; 10(4 Pt 1):440-6. Morikang E, Benson SC, Kurtz TW, Pershadsingh HA. PMID: 9128211.
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    121. Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. J Clin Invest. 1997 Feb 15; 99(4):577-81. Kren V, Pravenec M, Lu S, Krenova D, Wang JM, Wang N, Merriouns T, Wong A, St Lezin E, Lau D, Szpirer C, Szpirer J, Kurtz TW. PMID: 9045857.
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    122. Use of AFLP markers for gene mapping and QTL detection in the rat. Genomics. 1996 Nov 01; 37(3):289-94. Otsen M, den Bieman M, Kuiper MT, Pravenec M, Kren V, Kurtz TW, Jacob HJ, Lankhorst A, van Zutphen BF. PMID: 8938440.
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    123. Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat. J Clin Invest. 1996 Aug 01; 98(3):856-62. Bottger A, van Lith HA, Kren V, Krenová D, Bílá V, Vorlícek J, Zídek V, Musilová A, Zdobinská M, Wang JM, van Zutphen BF, Kurtz TW, Pravenec M. PMID: 8698878.
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    124. Linkage mapping of the carboxyl ester lipase gene (Cel) to rat chromosome 3. Mamm Genome. 1996 Jul; 7(7):559-60. Pravenec M, Kren V, Wang J, Bottger A, van Zutphen LF, Kurtz TW. PMID: 8672150.
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    125. A genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome. 1996 Feb; 7(2):117-27. Pravenec M, Gauguier D, Schott JJ, Buard J, Kren V, Bílá V, Szpirer C, Szpirer J, Wang JM, Huang H, St Lezin E, Spence MA, Flodman P, Printz M, Lathrop GM, Vergnaud G, Kurtz TW. PMID: 8835528.
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    126. Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J Clin Invest. 1996 Jan 15; 97(2):522-7. St Lezin EM, Pravenec M, Wong AL, Liu W, Wang N, Lu S, Jacob HJ, Roman RJ, Stec DE, Wang JM, Reid IA, Kurtz TW. PMID: 8567976.
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    127. Genetic linkage maps of the rat derived from an intercross and recombinant inbred strains originating from the BN.Lx and SHR progenitors. Folia Biol (Praha). 1996; 42(4):147-53. Pravenec M, Kren V, Bílá V, Krenová D, Zdobinská M, Kurtz TW. PMID: 8997634.
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    128. Mapping and sequence analysis of the gene encoding the beta subunit of the epithelial sodium channel in experimental models of hypertension. J Hypertens. 1995 Nov; 13(11):1247-51. Huang H, Pravenec M, Wang JM, Kren V, St Lezin E, Szpirer C, Szpirer J, Kurtz TW. PMID: 8984121.
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    129. Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension. J Biol Chem. 1995 Jul 14; 270(28):16555-60. Cover CM, Wang JM, St Lezin E, Kurtz TW, Mellon SH. PMID: 7622461.
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    130. A genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet. 1995 Jan; 9(1):63-9. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodman A, Koike G, Kren V, Kurtz T, Lernmark A. PMID: 7704027.
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    131. Frequency of a deletion polymorphism in the gene for angiotensin converting enzyme is increased in African-Americans with hypertension. Am J Hypertens. 1994 Aug; 7(8):759-62. Duru K, Farrow S, Wang JM, Lockette W, Kurtz T. PMID: 7986468.
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    132. Genetic models of hypertension. Lancet. 1994 Jul 16; 344(8916):167-8. Kurtz TW. PMID: 7912769.
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    133. Cosegregation of the endothelin-3 locus with blood pressure and relative heart weight in inbred Dahl rats. J Hypertens. 1994 Jun; 12(6):643-51. Cicila GT, Rapp JP, Bloch KD, Kurtz TW, Pravenec M, Kren V, Hong CC, Quertermous T, Ng SC. PMID: 7963489.
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    134. Genetic analysis of alpha 2-adrenergic receptors and blood pressure using Dahl salt-sensitive rats. J Hypertens. 1994 Apr; 12(4):357-65. Ginn DI, Baptista CA, Alam KY, Deng AY, Dene H, Le H, Kurtz TW, Rapp JP. PMID: 8064159.
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    135. Linkage mapping of alkaline phosphatase 1, inhibin alpha subunit, and gamma-crystallin 1 on rat chromosome 9 and Na+, K(+)-ATPase alpha 2 subunit, renin, and leukocyte common antigen on rat chromosome 13. Genomics. 1994 Jan 01; 19(1):190-1. Pravenec M, St Lezin EM, Kren V, Wang JM, Kurtz TW. PMID: 8188231.
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    136. The renin gene and hypertension. Semin Nephrol. 1993 Nov; 13(6):581-5. St Lezin EM, Kurtz TW. PMID: 8278692.
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    137. Linkage between the RT8 alloantigen and interleukin 6 loci on the rat chromosome 4. Transplant Proc. 1993 Oct; 25(5):2777. Kren V, Pravenec M, Bila V, Svobodova D, St Lezin E, Kurtz TW. PMID: 8105577.
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    138. Potassium preserves endothelial function and enhances aortic compliance in Dahl rats. Hypertension. 1993 Sep; 22(3):315-22. Sudhir K, Kurtz TW, Yock PG, Connolly AJ, Morris RC. PMID: 8349324.
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    139. New genetic models for hypertension research. Trends Cardiovasc Med. 1993 Jul-Aug; 3(4):119-23. Lezin EM, Pravenec M, Kurtz TW. PMID: 21244937.
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    140. Assignment of the chromogranin A (Chga) locus to homologous regions on mouse chromosome 12 and rat chromosome 6. Genomics. 1993 Jul; 17(1):252-5. Simon-Chazottes D, Wu H, Parmer RJ, Rozansky DJ, Szpirer J, Levan G, Kurtz TW, Szpirer C, Guenet JL, O'Connor DT. PMID: 8406464.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    141. Effects of ciglitazone on blood pressure and intracellular calcium metabolism. Hypertension. 1993 Jun; 21(6 Pt 2):1020-3. Pershadsingh HA, Szollosi J, Benson S, Hyun WC, Feuerstein BG, Kurtz TW. PMID: 8505086.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    142. Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nat Genet. 1993 Apr; 3(4):346-53. Cicila GT, Rapp JP, Wang JM, St Lezin E, Ng SC, Kurtz TW. PMID: 7981756.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    143. Transgenic models of hypertension: useful tools or unusual toys? J Clin Invest. 1993 Mar; 91(3):741. Kurtz TW. PMID: 8450055.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    144. Genetics of essential hypertension. Am J Med. 1993 Jan; 94(1):77-84. Kurtz TW, Spence MA. PMID: 8420305.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    145. Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat. Biochem Biophys Res Commun. 1992 Oct 15; 188(1):64-9. Iwai N, Kurtz TW, Inagami T. PMID: 1417869.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    146. Gene mapping in experimental hypertension. J Am Soc Nephrol. 1992 Jul; 3(1):28-34. Kurtz TW, St Lezin EM. PMID: 1327257.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    147. Genetic heterogeneity and differences in glomerular hemodynamics between inbred colonies of Munich-Wistar rats. J Am Soc Nephrol. 1992 Jul; 3(1):66-72. Fenoy FJ, St Lezin E, Kurtz TW, Roman RJ. PMID: 1391710.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    148. Hypertensive strains and normotensive 'control' strains. How closely are they related? Hypertension. 1992 May; 19(5):419-24. St Lezin E, Simonet L, Pravenec M, Kurtz TW. PMID: 1568758.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    149. Genetic approaches to hypertension. Ann Med. 1992 Apr; 24(2):81-3. Kurtz TW. PMID: 1610544.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    150. Assignment of rat linkage group V to chromosome 19 by single-strand conformation polymorphism analysis of somatic cell hybrids. Genomics. 1992 Feb; 12(2):350-6. Pravenec M, Simonet L, Kren V, St Lezin E, Levan G, Szpirer J, Szpirer C, Kurtz T. PMID: 1740344.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    151. Sequence analysis of the alpha 1 Na+,K(+)-ATPase gene in the Dahl salt-sensitive rat. Hypertension. 1991 Nov; 18(5):689-93. Simonet L, St Lezin E, Kurtz TW. PMID: 1657773.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    152. Identification of genes determining spontaneous hypertension. Review article. Sb Lek. 1991 Jun; 93(5-6):136-41. Pravenec M, Kren V, Klír P, Simonet L, Kurtz T. PMID: 1798912.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    153. Measurement of aortic blood flow by Doppler echocardiography: day to day variability in normal subjects and applicability in clinical research. J Am Coll Cardiol. 1991 May; 17(6):1326-33. Moulinier L, Venet T, Schiller NB, Kurtz TW, Morris RC, Sebastian A. PMID: 2016450.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    154. The rat renin gene: assignment to chromosome 13 and linkage to the regulation of blood pressure. Genomics. 1991 Mar; 9(3):466-72. Pravenec M, Simonet L, Kren V, Kunes J, Levan G, Szpirer J, Szpirer C, Kurtz T. PMID: 1674497.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    155. Cosegregation of blood pressure with a kallikrein gene family polymorphism. Hypertension. 1991 Feb; 17(2):242-6. Pravenec M, Kren V, Kunes J, Scicli AG, Carretero OA, Simonet L, Kurtz TW. PMID: 1671381.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    156. Linkage between renin and fumarate hydratase genes in the rat. Transplant Proc. 1990 Dec; 22(6):2555. Pravenec M, Kabra P, Kren V, Simonet L, Kurtz TW. PMID: 1979894.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    157. Genetic analysis of polydactyly-luxate syndrome in the rat. Transplant Proc. 1990 Dec; 22(6):2588-9. Kren V, Pravenec M, Bílá V, Daniel R, Stursa P, Hevkovský P, Kurtz TW. PMID: 2264164.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    158. Biometric genetic analysis of blood pressure in the spontaneously hypertensive rat. Hypertension. 1990 Dec; 16(6):718-24. Kurtz TW, Casto R, Simonet L, Printz MP. PMID: 2246038.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    159. Laboratory monitoring of cyclosporine levels: guidelines for the dermatologist. J Am Acad Dermatol. 1990 Dec; 23(6 Pt 2):1275-8; discussion 1278-9. Mockli G, Kabra PM, Kurtz TW. PMID: 2277135.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    160. HXB and BXH sets of recombinant inbred strains: strain distribution patterns of some genetic markers. Transplant Proc. 1990 Dec; 22(6):2557-8. Pravenec M, Kren V, Bílá V, Kabra P, Krsiaková M, Simonet L, Kurtz TW. PMID: 2264149.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    161. Sodium-calcium interactions and salt-sensitive hypertension. Am J Hypertens. 1990 Aug; 3(8 Pt 2):152S-155S. Kurtz TW, Morris RC. PMID: 2222961.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    162. Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. J Clin Invest. 1990 Apr; 85(4):1328-32. Kurtz TW, Simonet L, Kabra PM, Wolfe S, Chan L, Hjelle BL. PMID: 1969424.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    163. Regulation of hepatic inorganic phosphate and ATP in response to fructose loading: an in vivo 31P-NMR study. Biochim Biophys Acta. 1989 Jul 11; 1012(2):121-7. Karczmar GS, Kurtz T, Tavares NJ, Weiner MW. PMID: 2742879.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    164. The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension. 1989 Jun; 13(6 Pt 2):896-901. Kurtz TW, Morris RC, Pershadsingh HA. PMID: 2786848.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    165. Molecular evidence of genetic heterogeneity in Wistar-Kyoto rats: implications for research with the spontaneously hypertensive rat. Hypertension. 1989 Feb; 13(2):188-92. Kurtz TW, Montano M, Chan L, Kabra P. PMID: 2914738.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    166. Prolonged continuous versus intermittent oral acyclovir treatment in normal adults with frequently recurring genital herpes simplex virus infection. Am J Med. 1988 Aug 29; 85(2A):14-9. Mertz GJ, Eron L, Kaufman R, Goldberg L, Raab B, Conant M, Mills J, Kurtz T, Davis LG. PMID: 3044076.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    167. Biological variability in Wistar-Kyoto and spontaneously hypertensive rats. Hypertension. 1988 Jan; 11(1):106. Kurtz TW, Morris RC. PMID: 3338836.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    168. "Salt-sensitive" essential hypertension in men. Is the sodium ion alone important? N Engl J Med. 1987 Oct 22; 317(17):1043-8. Kurtz TW, Al-Bander HA, Morris RC. PMID: 3309653.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    169. Biological variability in Wistar-Kyoto rats. Implications for research with the spontaneously hypertensive rat. Hypertension. 1987 Jul; 10(1):127-31. Kurtz TW, Morris RC. PMID: 3596765.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    170. Attenuation of deoxycorticosterone-induced hypertension by supplemental dietary calcium. J Hypertens Suppl. 1986 Dec; 4(5):S129-31. Kurtz TW, Morris RC. PMID: 3471893.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    171. Evidence for a difference in vitamin D metabolism between spontaneously hypertensive and Wistar-Kyoto rats. Hypertension. 1986 Nov; 8(11):1015-20. Kurtz TW, Portale AA, Morris RC. PMID: 3770864.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    172. Liquid-chromatographic measurements of inosine, hypoxanthine, and xanthine in studies of fructose-induced degradation of adenine nucleotides in humans and rats. Clin Chem. 1986 May; 32(5):782-6. Kurtz TW, Kabra PM, Booth BE, Al-Bander HA, Portale AA, Serena BG, Tsai HC, Morris RC. PMID: 3698269.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    173. Sodium chloride-dependent hypertension. Hypertension. 1986 Apr; 8(4):359-60. Kurtz TW, Morris RC. PMID: 3957420.
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    174. Hypertension in the recently weaned Dahl salt-sensitive rat despite a diet deficient in sodium chloride. Science. 1985 Nov 15; 230(4727):808-10. Kurtz TW, Morris RC. PMID: 4059913.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    175. Hypertension and sodium salts. Science. 1985 Apr 19; 228(4697):351-3. Liebman BF, Langford HG, Whitescarver SA, Ott CE, Jackson B, Kurtz TW, Morris RC. PMID: 3983634.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    176. Liebman and langford. Science. 1985 Apr 19; 228(4697):352-3. Kurtz TW, Morris RC. PMID: 17790239.
      View in: PubMed   Mentions:    Fields:    
    177. Dietary chloride as a determinant of disordered calcium metabolism in salt-dependent hypertension. Life Sci. 1985 Mar 11; 36(10):921-9. Kurtz TW, Morris RC. PMID: 2983159.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    178. Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension. J Hypertens Suppl. 1984 Dec; 2(3):S371-3. Kurtz TW, Morris RC. PMID: 6100744.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    179. Dietary chloride as a determinant of "sodium-dependent" hypertension. Science. 1983 Dec 09; 222(4628):1139-41. Kurtz TW, Morris RC. PMID: 6648527.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    180. Segmental renal vascular resistance in the spontaneously hypertensive rat. Am J Physiol. 1982 Jun; 242(6):H961-6. Hsu CH, Slavicek JH, Kurtz TW. PMID: 7091356.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    181. Effect of exogenous angiotensin II on renal hemodynamics in the awake rat. Measurement of afferent arteriolar diameter by the microsphere method. Circ Res. 1980 May; 46(5):646-50. Hsu CH, Kurtz TW, Slavicek JM. PMID: 7363414.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    182. Intrarenal vascular resistance in glycerol-induced acute renal failure in the rat. Circ Res. 1979 Nov; 45(5):583-7. Hsu CH, Kurtz TW, Sands CE. PMID: 487520.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    183. Familial azotemia. Impaired urea excretion despite normal renal function. N Engl J Med. 1978 Jan 19; 298(3):117-21. Hsu CH, Kurtz TW, Massari PU, Ponze SA, Chang BS. PMID: 619239.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    184. Systemic hemodynamics in nephrotoxic acute renal failure. Nephron. 1978; 21(2):100-6. Kurtz TW, Hsu CH. PMID: 673089.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    185. Renal tubular sodium and water excretion in antibiotic-induced nephrotoxicity. Renal function in antibiotic nephrotoxicity. Nephron. 1978; 20(4):227-34. Hsu CH, Maletz RM, Rozas VV, Kurtz TW. PMID: 634420.
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    186. Cardiac output and renal blood flow in glycerol-induced acute renal failure in the rat. Circ Res. 1977 Feb; 40(2):178-82. Hsu CH, Kurtz TW, Waldinger TP. PMID: 844143.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    187. Renal hemodynamics in HgCl2-induced acute renal failure. Nephron. 1977; 18(6):326-32. Hsu CH, Kurtz TW, Rosenzweig J, Weller JM. PMID: 876439.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    188. [Inhibition of natriuretic effect of angiotensin by spirolactones and salidiuretics in cirrhosis and arterial hypertension]. Pathol Biol (Paris). 1969 May; 17(9):447-58. Kuntzmann F, Reville P, Kurtz T, Jahn H, Stahl J. PMID: 4308377.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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