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Positive cfDNA screening results for 22q11.2 deletion syndrome-Clinical and laboratory considerations. Front Genet. 2023; 14:1146669.
Soster E, Dyr B, Rafalko J, Almasri E, Cacheris P. PMID: 36968594; PMCID: PMC10036386.
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PubMed Mentions:
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Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial. Ann Intern Med. 2022 09; 175(9):1266-1274.
ACTIV-3/TICO Study Group, Barkauskas C, Mylonakis E, Poulakou G, Young BE, Vock DM, Siegel L, Engen N, Grandits G, Mosaly NR, Vekstein AM, Rogers R, Shehadeh F, Kaczynski M, Mylona EK, Syrigos KN, Rapti V, Lye DC, Hui DS, Leither L, Knowlton KU, Jain MK, Marines-Price R, Osuji A, Overcash JS, Kalomenidis I, Barmparessou Z, Waters M, Zepeda K, Chen P, Torbati S, Kiweewa F, Sebudde N, Almasri E, Hughes A, Bhagani SR, Rodger A, Sandkovsky U, Gottlieb RL, Nnakelu E, Trautner B, Menon V, Lutaakome J, Matthay M, Robinson P, Protopapas K, Koulouris N, Kimuli I, Baduashvili A, Braun DL, Günthard HF, Ramachandruni S, Kidega R, Kim K, Hatlen TJ, Phillips AN, Murray DD, Jensen TO, Padilla ML, Accardi EX, Shaw-Saliba K, Dewar RL, Teitelbaum M, Natarajan V, Laverdure S, Highbarger HC, Rehman MT, Vogel S, Vallée D, Crew P, Atri N, Schechner AJ, Pett S, Hudson F, Badrock J, Touloumi G, Brown SM, Self WH, North CM, Ginde AA, Chang CC, Kelleher A, Nagy-Agren S, Vasudeva S, Looney D, Nguyen HH, Sánchez A, Weintrob AC, Grund B, Sharma S, Reilly CS, Paredes R, Bednarska A, Gerry NP, Babiker AG, Davey VJ, Gelijns AC, Higgs ES, Kan V, Matthews G, Thompson BT, Legenne P, Chandra R, Lane HC, Neaton JD, Lundgren JD. PMID: 35939810; PMCID: PMC9384272.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial. Lancet Respir Med. 2022 09; 10(9):888-899.
Wolfe CR, Tomashek KM, Patterson TF, Gomez CA, Marconi VC, Jain MK, Yang OO, Paules CI, Palacios GMR, Grossberg R, Harkins MS, Mularski RA, Erdmann N, Sandkovsky U, Almasri E, Pineda JR, Dretler AW, de Castilla DL, Branche AR, Park PK, Mehta AK, Short WR, McLellan SLF, Kline S, Iovine NM, El Sahly HM, Doernberg SB, Oh MD, Huprikar N, Hohmann E, Kelley CF, Holodniy M, Kim ES, Sweeney DA, Finberg RW, Grimes KA, Maves RC, Ko ER, Engemann JJ, Taylor BS, Ponce PO, Larson L, Melendez DP, Seibert AM, Rouphael NG, Strebe J, Clark JL, Julian KG, de Leon AP, Cardoso A, de Bono S, Atmar RL, Ganesan A, Ferreira JL, Green M, Makowski M, Bonnett T, Beresnev T, Ghazaryan V, Dempsey W, Nayak SU, Dodd LE, Beigel JH, Kalil AC, ACTT-4 Study Group. PMID: 35617986; PMCID: PMC9126560.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Assessing CAR T-Cell Therapy Response Using Genome-Wide Sequencing of Cell-Free DNA in Patients With B-Cell Lymphomas. Transplant Cell Ther. 2022 01; 28(1):30.e1-30.e7.
Goodman AM, Holden KA, Jeong AR, Kim L, Fitzgerald KD, Almasri E, McLennan G, Eisenberg M, Jahromi AH, Hoh C, Hurley M, Mulroney C, Tzachanis D, Ball ED, Jensen TJ, Kurzrock R. PMID: 34655803.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Genome-wide Sequencing of Cell-free DNA Enables Detection of Copy-number Alterations in Patients with Cancer Where Tissue Biopsy is Not Feasible. Mol Cancer Ther. 2021 11; 20(11):2274-2279.
Jensen TJ, Goodman AM, Ellison CK, Holden KA, Kato S, Kim L, Daniels GA, Fitzgerald K, McCarthy E, Nakashe P, Mazloom AR, Almasri E, McLennan G, Grosu DS, Eisenberg M, Kurzrock R. PMID: 34465593.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Correction to: Three years of clinical experience with a genome-wide cfDNA screening test for aneuploidies and copy number variants. Genet Med. 2021 Jul; 23(7):1378.
Soster E, Boomer T, Hicks S, Caldwell S, Dyr B, Chibuk J, Almasri E. PMID: 33958750; PMCID: PMC8257495.
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PubMed Mentions:
1 Fields:
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Genome-wide cell-free DNA screening: a focus on copy-number variants. Genet Med. 2021 10; 23(10):1847-1853.
Rafalko J, Soster E, Caldwell S, Almasri E, Westover T, Weinblatt V, Cacheris P. PMID: 34155363; PMCID: PMC8486654.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Three years of clinical experience with a genome-wide cfDNA screening test for aneuploidies and copy-number variants. Genet Med. 2021 07; 23(7):1349-1355.
Soster E, Boomer T, Hicks S, Caldwell S, Dyr B, Chibuk J, Almasri E. PMID: 33731879; PMCID: PMC8257487.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Application of mosaicism ratio to multifetal gestations. PLoS One. 2021; 16(3):e0248467.
Rafalko J, Caldwell S, Soster E, Almasri E, McLennan G, Liu T, Weinblatt V, Cacheris P, McCullough R. PMID: 33711042; PMCID: PMC7954340.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
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Not all low fetal fraction cell-free DNA screening failures are at increased risk for aneuploidy. Prenat Diagn. 2021 Oct; 41(11):1372-1379.
Caldwell S, Almasri E, Schmidt L, Xu C, Dyr B, Wardrop J, Cacheris P. PMID: 33682142; PMCID: PMC8596865.
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PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2020 12 01; 324(21):2165-2176.
Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM, National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger R, Wang H, Vidales E, Patel B, Ginde A, Moss M, Baduashvili A, McKeehan J, Finck L, Higgins C, Howell M, Douglas I, Haukoos J, Hiller T, Lyle C, Cupelo A, Caruso E, Camacho C, Gravitz S, Finigan J, Griesmer C, Park P, Hyzy R, Nelson K, McDonough K, Olbrich N, Williams M, Kapoor R, Nash J, Willig M, Ford H, Gardner-Gray J, Ramesh M, Moses M, Ng Gong M, Aboodi M, Asghar A, Amosu O, Torres M, Kaur S, Chen JT, Hope A, Lopez B, Rosales K, Young You J, Mosier J, Hypes C, Natt B, Borg B, Salvagio Campbell E, Hite RD, Hudock K, Cresie A, Alhasan F, Gomez-Arroyo J, Duggal A, Mehkri O, Hastings A, Sahoo D, Abi Fadel F, Gole S, Shaner V, Wimer A, Meli Y, King A, Terndrup T, Exline M, Pannu S, Robart E, Karow S, Hough C, Robinson B, Johnson N, Henning D, Campo M, Gundel S, Seghal S, Katsandres S, Dean S, Khan A, Krol O, Jouzestani M, Huynh P, Weissman A, Yealy D, Scholl D, Adams P, McVerry B, Huang D, Angus D, Schooler J, Moore S, Files C, Miller C, Gibbs K, LaRose M, Flores L, Koehler L, Morse C, Sanders J, Langford C, Nanney K, MdalaGausi M, Yeboah P, Morris P, Sturgill J, Seif S, Cassity E, Dhar S, de Wit M, Mason J, Goodwin A, Hall G, Grady A, Chamberlain A, Brown S, Bledsoe J, Leither L, Peltan I, Starr N, Fergus M, Aston V, Montgomery Q, Smith R, Merrill M, Brown K, Armbruster B, Harris E, Middleton E, Paine R, Johnson S, Barrios M, Eppensteiner J, Limkakeng A, McGowan L, Porter T, Bouffler A, Leahy JC, deBoisblanc B, Lammi M, Happel K, Lauto P, Self W, Casey J, Semler M, Collins S, Harrell F, Lindsell C, Rice T, Stubblefield W, Gray C, Johnson J, Roth M, Hays M, Torr D, Zakaria A, Schoenfeld D, Thompson T, Hayden D, Ringwood N, Oldmixon C, Ulysse C, Morse R, Muzikansky A, Fitzgerald L, Whitaker S, Lagakos A, Brower R, Reineck L, Aggarwal N, Bienstock K, Freemer M, Maclawiw M, Weinmann G, Morrison L, Gillespie M, Kryscio R, Brodie D, Zareba W, Rompalo A, Boeckh M, Parsons P, Christie J, Hall J, Horton N, Zoloth L, Dickert N, Diercks D. PMID: 33165621; PMCID: PMC7653542.
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PubMed Mentions:
211 Fields:
Translation:
Humans
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Impact of mosaicism ratio on positive predictive value of cfDNA screening. Prenat Diagn. 2021 01; 41(1):28-34.
Rafalko JM, Caldwell S, Tynan J, Almasri E, Weinblatt V, McCullough R. PMID: 33151555; PMCID: PMC7894494.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Cell-free DNA screening in twin pregnancies: A more accurate and reliable screening tool. Prenat Diagn. 2020 09; 40(10):1321-1329.
Chibuk J, Rafalko J, Boomer T, McCullough R, McLennan G, Wyatt P, Almasri E. PMID: 32677048; PMCID: PMC7540584.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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A new era in aneuploidy screening: cfDNA testing in >30,000 multifetal gestations: Experience at one clinical laboratory. PLoS One. 2019; 14(8):e0220979.
Dyr B, Boomer T, Almasri EA, Wardrop JL, Rafalko J, Chibuk J, McCullough RM. PMID: 31393959; PMCID: PMC6687285.
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PubMed Mentions:
4 Fields:
Translation:
HumansPHPublic Health
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Incidental Detection of Maternal Neoplasia in Noninvasive Prenatal Testing. Clin Chem. 2018 02; 64(2):329-335.
Dharajiya NG, Grosu DS, Farkas DH, McCullough RM, Almasri E, Sun Y, Kim SK, Jensen TJ, Saldivar JS, Topol EJ, van den Boom D, Ehrich M. PMID: 28982650.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Genome-wide cfDNA screening: clinical laboratory experience with the first 10,000 cases. Genet Med. 2017 12; 19(12):1332-1337.
Ehrich M, Tynan J, Mazloom A, Almasri E, McCullough R, Boomer T, Grosu D, Chibuk J. PMID: 28617416.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants. Am J Obstet Gynecol. 2016 Aug; 215(2):227.e1-227.e16.
Lefkowitz RB, Tynan JA, Liu T, Wu Y, Mazloom AR, Almasri E, Hogg G, Angkachatchai V, Zhao C, Grosu DS, McLennan G, Ehrich M. PMID: 26899906.
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PubMed Mentions:
51 Fields:
Translation:
Humans
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Clinical outcome of subchromosomal events detected by whole-genome noninvasive prenatal testing. Prenat Diagn. 2015 Oct; 35(10):999-1004.
Helgeson J, Wardrop J, Boomer T, Almasri E, Paxton WB, Saldivar JS, Dharajiya N, Monroe TJ, Farkas DH, Grosu DS, McCullough RM. PMID: 26088833; PMCID: PMC5034801.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Factors affecting levels of circulating cell-free fetal DNA in maternal plasma and their implications for noninvasive prenatal testing. Prenat Diagn. 2015 Aug; 35(8):816-22.
Kinnings SL, Geis JA, Almasri E, Wang H, Guan X, McCullough RM, Bombard AT, Saldivar JS, Oeth P, Deciu C. PMID: 26013964.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Uterine leiomyoma confounding a noninvasive prenatal test result. Prenat Diagn. 2015 Oct; 35(10):990-3.
Dharajiya NG, Namba A, Horiuchi I, Miyai S, Farkas DH, Almasri E, Saldivar JS, Takagi K, Kamei Y. PMID: 26058600.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Non-invasive prenatal chromosomal aneuploidy testing--clinical experience: 100,000 clinical samples. PLoS One. 2014; 9(10):e109173.
McCullough RM, Almasri EA, Guan X, Geis JA, Hicks SC, Mazloom AR, Deciu C, Oeth P, Bombard AT, Paxton B, Dharajiya N, Saldivar JS. PMID: 25289665; PMCID: PMC4188614.
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PubMed Mentions:
39 Fields:
Translation:
Humans
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Rank-based edge reconstruction for scale-free genetic regulatory networks. BMC Bioinformatics. 2008 Jan 31; 9:75.
Chen G, Larsen P, Almasri E, Dai Y. PMID: 18237422; PMCID: PMC2275249.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microarray experiments. BMC Bioinformatics. 2007 Aug 29; 8:317.
Larsen P, Almasri E, Chen G, Dai Y. PMID: 17727721; PMCID: PMC2082045.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Hyperchloremic acidosis increases circulating inflammatory molecules in experimental sepsis. Chest. 2006 Oct; 130(4):962-7.
Kellum JA, Song M, Almasri E. PMID: 17035425.
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PubMed Mentions:
77 Fields:
Translation:
Animals
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Sample scale-free gene regulatory network using gene ontology. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:5523-6.
Chen G, Larsen P, Almasri E, Dai Y. PMID: 17946312.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Correlated Discretized Expression score: a method for identifying gene interaction networks from time course microarray expression data. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:5842-5.
Larsen P, Almasri E, Chen G, Dai Y. PMID: 17946340.
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PubMed Mentions: Fields:
Translation:
Animals
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Water and solute permeability of rat lung caveolae: high permeabilities explained by acyl chain unsaturation. Am J Physiol Cell Physiol. 2005 Jul; 289(1):C33-41.
Hill WG, Almasri E, Ruiz WG, Apodaca G, Zeidel ML. PMID: 15728712.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells