Kirsten Kangelaris, MD

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Phone415-476-4852
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    Collapse Biography 
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    University of California, San FranciscoM.A.S. in Clinical Research2010 Graduate Division (Advance Training in Clinical Research)
    University of Michigan Medical CenterInternal Medicine, Internship and Residency
    University of Michigan Medical SchoolMD

    Collapse Overview 
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    Dr. Kangelaris is an Associate Professor of Medicine in the Division of Hospital Medicine (DHM) in the Department of Medicine at the University of California San Francisco. She is the Associate Director of the Academic Hospital Medicine fellowship and an Inquiry Advisor at UCSF Medical School. She leads the DHM Works-in-Progress session, serves as the On-boarding Ambassador to new DHM faculty and fellows, and chairs the DHM Internal Grants Program. She serves as the Director of the DHM COVID-19 Planning Taskforce.
    Her research program is focused on the evolution of organ dysfunction in sepsis. She currently leads the clinical operations and data management of a large observational study of COVID-19 (COMET) and is co-investigator in several COVID-19 randomized controlled trials (ACTIV-3, ACTIV-4, I-SPY and ORCHID). A major objective of her research is to improve understanding of the heterogeneity of sepsis impacting physician recognition and disease-specific response to therapy. Her research encompasses several different approaches across the translational spectrum including electronic health record based-clinical studies, prospective clinical studies of adult patients combined with biomarker studies including DNA genomic, mRNA gene expression, plasma proteins and cell-based protein studies.
    Her clinical work focuses on the care of hospitalized adults and she attends on the teaching service at Moffitt-Long hospital.
    Dr. Kangelaris completed medical school, internship and residency in Internal Medicine at the University of Michigan Medical School, and completed a General Medicine Research Fellowship and a Master's of Advanced Studies in Clinical Research at UCSF. She joined faculty in the Division of Hospital Medicine at UCSF in 2010. She is a Fellow of the Society of Hospital Medicine (SHM) and member of the American Thoracic Society. She serves as the co-chair of the Research submissions for the RIV competition at SHM.

    Collapse Research 
    Collapse Research Activities and Funding
    Chemokine-related acute lung injury pathogenesis in African-American patients
    NIH K23HL116800Mar 1, 2013 - Feb 28, 2019
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identifying the Sickest During Triage: Using Point-of-Care Severity Scores to Predict Prognosis in Emergency Department Patients With Suspected Sepsis. J Hosp Med. 2021 Jul 21. Prasad PA, Fang MC, Martinez SP, Liu KD, Kangelaris KN. PMID: 34328843.
      View in: PubMed   Mentions:
    2. Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19. Res Sq. 2021 Apr 23. Tsitsiklis A, Zha B, Byrne A, DeVoe C, Levan S, Rackaityte E, Sunshine S, Mick E, Ghale R, Jauregui A, Neff N, Sarma A, Serpa P, Deiss T, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Jones N, Wu B, Darmanis S, Matthay M, Lynch S, DeRisi J, Consortium C, Hendrickson C, Kangelaris K, Krummel M, Woodruff P, Erle D, Rosenberg O, Calfee C, Langelier C. PMID: 34013247.
      View in: PubMed   Mentions:
    3. Impaired antibacterial immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19. medRxiv. 2021 Mar 26. Tsitsiklis A, Zha BS, Byrne A, Devoe C, Levan S, Rackaityte E, Sunshine S, Mick E, Ghale R, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Jones N, Wu B, Darmanis S, Matthay MA, Lynch SV, DeRisi JL, COMET Consortium+ , Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Rosenberg O, Calfee CS, Langelier CR. PMID: 33791731.
      View in: PubMed   Mentions:
    4. Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19. bioRxiv. 2021 Mar 10. van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Voyer TL, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, UCSF COMET consortium , Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ. PMID: 33758859.
      View in: PubMed   Mentions:
    5. Global absence and targeting of protective immune states in severe COVID-19. Nature. 2021 03; 591(7848):124-130. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Im KW, Serwas NK, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, UCSF COMET Consortium , Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33494096.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    6. COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone. Res Sq. 2021 Jan 14. Sarma A, Christenson S, Mick E, Deiss T, DeVoe C, Pisco A, Ghale R, Jauregui A, Byrne A, Moazed F, Spottiswoode N, Sinha P, Zha B, Neff N, Tan M, Serpa PH, Ansel KM, Wilson J, Leligdowicz A, Seigel E, Sirota M, DeRisi J, Matthay M, Consortium C, Hendrickson C, Kangelaris K, Krummel M, Woodruff P, Erle D, Calfee C, Langelier C. PMID: 33469573.
      View in: PubMed   Mentions:
    7. Evaluation of a novel metric for personalized opioid prescribing after hospitalization. PLoS One. 2020; 15(12):e0244735. Iverson NR, Lau CY, Abe-Jones Y, Fang MC, Kangelaris KN, Prasad P, Shah SJ, Najafi N. PMID: 33382802.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis. Am J Physiol Lung Cell Mol Physiol. 2021 May 01; 320(5):L892-L902. Kangelaris KN, Clemens R, Fang X, Jauregui A, Liu T, Vessel K, Deiss T, Sinha P, Leligdowicz A, Liu KD, Zhuo H, Alder MN, Wong HR, Calfee CS, Lowell C, Matthay MA. PMID: 33355521.
      View in: PubMed   Mentions:    Fields:    
    9. Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2020 12 01; 324(21):2165-2176. Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM, National Heart, Lung, and Blood Institute PETAL Clinical Trials Network , Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger R, Wang H, Vidales E, Patel B, Ginde A, Moss M, Baduashvili A, McKeehan J, Finck L, Higgins C, Howell M, Douglas I, Haukoos J, Hiller T, Lyle C, Cupelo A, Caruso E, Camacho C, Gravitz S, Finigan J, Griesmer C, Park P, Hyzy R, Nelson K, McDonough K, Olbrich N, Williams M, Kapoor R, Nash J, Willig M, Ford H, Gardner-Gray J, Ramesh M, Moses M, Ng Gong M, Aboodi M, Asghar A, Amosu O, Torres M, Kaur S, Chen JT, Hope A, Lopez B, Rosales K, Young You J, Mosier J, Hypes C, Natt B, Borg B, Salvagio Campbell E, Hite RD, Hudock K, Cresie A, Alhasan F, Gomez-Arroyo J, Duggal A, Mehkri O, Hastings A, Sahoo D, Abi Fadel F, Gole S, Shaner V, Wimer A, Meli Y, King A, Terndrup T, Exline M, Pannu S, Robart E, Karow S, Hough C, Robinson B, Johnson N, Henning D, Campo M, Gundel S, Seghal S, Katsandres S, Dean S, Khan A, Krol O, Jouzestani M, Huynh P, Weissman A, Yealy D, Scholl D, Adams P, McVerry B, Huang D, Angus D, Schooler J, Moore S, Files C, Miller C, Gibbs K, LaRose M, Flores L, Koehler L, Morse C, Sanders J, Langford C, Nanney K, MdalaGausi M, Yeboah P, Morris P, Sturgill J, Seif S, Cassity E, Dhar S, de Wit M, Mason J, Goodwin A, Hall G, Grady A, Chamberlain A, Brown S, Bledsoe J, Leither L, Peltan I, Starr N, Fergus M, Aston V, Montgomery Q, Smith R, Merrill M, Brown K, Armbruster B, Harris E, Middleton E, Paine R, Johnson S, Barrios M, Eppensteiner J, Limkakeng A, McGowan L, Porter T, Bouffler A, Leahy JC, deBoisblanc B, Lammi M, Happel K, Lauto P, Self W, Casey J, Semler M, Collins S, Harrell F, Lindsell C, Rice T, Stubblefield W, Gray C, Johnson J, Roth M, Hays M, Torr D, Zakaria A, Schoenfeld D, Thompson T, Hayden D, Ringwood N, Oldmixon C, Ulysse C, Morse R, Muzikansky A, Fitzgerald L, Whitaker S, Lagakos A, Brower R, Reineck L, Aggarwal N, Bienstock K, Freemer M, Maclawiw M, Weinmann G, Morrison L, Gillespie M, Kryscio R, Brodie D, Zareba W, Rompalo A, Boeckh M, Parsons P, Christie J, Hall J, Horton N, Zoloth L, Dickert N, Diercks D. PMID: 33165621.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    10. Alternative Tobacco Product Use in Critically Ill Patients. Int J Environ Res Public Health. 2020 11 24; 17(23). Liu T, Deiss TJ, Lippi MW, Jauregui A, Vessel K, Ke S, Belzer A, Zhuo H, Kangelaris KN, Gomez AD, Matthay MA, Liu KD, Calfee CS. PMID: 33255164.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses. Nat Commun. 2020 11 17; 11(1):5854. Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Castañeda G, DeRisi JL, Detweiler AM, Hao SL, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Calfee CS, Christenson SA, Kistler A, Langelier C. PMID: 33203890.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsPHPublic Health
    12. Global Absence and Targeting of Protective Immune States in Severe COVID-19. bioRxiv. 2020 Oct 29. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33140050.
      View in: PubMed   Mentions:
    13. Using best subset regression to identify clinical characteristics and biomarkers associated with sepsis-associated acute kidney injury. Am J Physiol Renal Physiol. 2020 12 01; 319(6):F979-F987. Kwong YD, Mehta KM, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson C, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD. PMID: 33044866.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: A retrospective cohort study of patients with and without COVID-19. EClinicalMedicine. 2020 Oct; 27:100518. Shah SJ, Barish PN, Prasad PA, Kistler A, Neff N, Kamm J, Li LM, Chiu CY, Babik JM, Fang MC, Abe-Jones Y, Alipanah N, Alvarez FN, Botvinnik OB, Castaneda G, CZB CLIAhub Consortium , Dadasovich RM, Davis J, Deng X, DeRisi JL, Detweiler AM, Federman S, Haliburton J, Hao S, Kerkhoff AD, Kumar GR, Malcolm KB, Mann SA, Martinez S, Mary RK, Mick E, Mwakibete L, Najafi N, Peluso MJ, Phelps M, Pisco AO, Ratnasiri K, Rubio LA, Sellas A, Sherwood KD, Sheu J, Spottiswoode N, Tan M, Yu G, Kangelaris KN, Langelier C. PMID: 32864588.
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    15. Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time. Crit Care Med. 2020 06; 48(6):830-837. Schwede M, Lee RY, Zhuo H, Kangelaris KN, Jauregui A, Vessel K, Belzer A, Deiss T, Matthay MA, Liu KD, Calfee CS. PMID: 32317598.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis. Intensive Care Med. 2020 06; 46(6):1222-1231. Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS. PMID: 32206845.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    17. Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. Crit Care Med. 2020 02; 48(2):200-209. Prasad PA, Fang MC, Abe-Jones Y, Calfee CS, Matthay MA, Kangelaris KN. PMID: 31939788.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1). Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    19. Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study. Crit Care. 2019 12 09; 23(1):400. Anderson BJ, Calfee CS, Liu KD, Reilly JP, Kangelaris KN, Shashaty MGS, Lazaar AL, Bayliffe AI, Gallop RJ, Miano TA, Dunn TG, Johansson E, Abbott J, Jauregui A, Deiss T, Vessel K, Belzer A, Zhuo H, Matthay MA, Meyer NJ, Christie JD. PMID: 31818332.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. The Association between Limited English Proficiency and Sepsis Mortality. J Hosp Med. 2019 Nov 20; 14:E1-E7. Jacobs ZG, Prasad PA, Fang MC, Abe-Jones Y, Kangelaris KN. PMID: 31891556.
      View in: PubMed   Mentions: 2     Fields:    
    21. ASSOCIATION OF ANGIOPOIETIN-2 AND ATRIAL FIBRILLATION BURDEN IN CRITICALLY ILL PATIENTS. Journal of the American College of Cardiology. 2019 Mar 1; 73(9):403. Lily Stern, Kathleen Liu, Hanjing Zhuo, Kirsten Kangelaris, Antonio Gomez, Alejandra Jauregui, Kathryn Vessel, Thomas Deiss, Jason Abbott, Ashish Agrawal, Michael Matthay, Carolyn S. Calfee, Liviu Klein. .
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    22. External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome. Intensive Care Med. 2017 Aug; 43(8):1123-1131. Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB. PMID: 28593401.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    23. Acute Respiratory Distress Syndrome Subphenotypes Respond Differently to Randomized Fluid Management Strategy. Am J Respir Crit Care Med. 2017 02 01; 195(3):331-338. Famous KR, Delucchi K, Ware LB, Kangelaris KN, Liu KD, Thompson BT, Calfee CS, ARDS Network . PMID: 27513822.
      View in: PubMed   Mentions: 166     Fields:    Translation:Humans
    24. Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Survey of Anesthesiology. 2016 Dec 1; 60(6):234-235. Kirsten Neudoerffer Kangelaris, Lorraine B. Ware, Chen Yu Wang, David R. Janz, Hanjing Zhuo, Michael A. Matthay, Carolyn S. Calfee. .
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    25. The authors reply. Crit Care Med. 2016 08; 44(8):e769-70. Kangelaris KN, Ware LB, Matthay MA, Calfee CS. PMID: 27428148.
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    26. The authors reply. Crit Care Med. 2016 08; 44(8):e771. Kangelaris KN, Ware LB, Matthay MA, Calfee CS. PMID: 27428150.
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    27. Implementation and evaluation of a "works-in-progress" session to promote scholarship in an academic hospitalist group. J Hosp Med. 2016 10; 11(10):719-723. Patel H, Fang MC, Harrison JD, Auerbach A, Kangelaris KN. PMID: 27294477.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Crit Care Med. 2016 Jan; 44(1):120-9. Kangelaris KN, Ware LB, Wang CY, Janz DR, Zhuo H, Matthay MA, Calfee CS. PMID: 26474112.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    29. Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med. 2015 Sep; 43(9):1790-7. Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. PMID: 26010690.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansPHPublic Health
    30. Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. Chest. 2015 Jun; 147(6):1539-1548. Calfee CS, Janz DR, Bernard GR, May AK, Kangelaris KN, Matthay MA, Ware LB. PMID: 26033126.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    31. Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS. . 2015 Jun 01; 308(11):L1102-13. Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS. PMID: 25795726.
      View in: PubMed   Mentions:
    32. Erratum to: plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. Intensive Care Med. 2015 Mar; 41(3):574. Sapru A, Calfee CS, Liu KD, Kangelaris K, Hansen H, Pawlikowska L, Ware LB, Alkhouli MF, Abbott J, Matthay MA, NHLBI ARDS Network . PMID: 25708422.
      View in: PubMed   Mentions:    Fields:    
    33. Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. Intensive Care Med. 2015 Mar; 41(3):470-8. Sapru A, Calfee CS, Liu KD, Kangelaris K, Hansen H, Pawlikowska L, Ware LB, Alkhouli MF, Abbott J, Abbot J, Matthay MA, NHLBI ARDS Network . PMID: 25643902.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    34. From storm to suppression in sepsis: are bands the link?*. Crit Care Med. 2014 Sep; 42(9):2135-6. Kangelaris KN, Seeley EJ. PMID: 25126801.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    35. Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Ann Intensive Care. 2014; 4:22. Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA. PMID: 25593740.
      View in: PubMed   Mentions:
    36. Intensive care unit scoring systems outperform emergency department scoring systems for mortality prediction in critically ill patients: a prospective cohort study. J Intensive Care. 2014; 2:40. Moseson EM, Zhuo H, Chu J, Stein JC, Matthay MA, Kangelaris KN, Liu KD, Calfee CS. PMID: 25960880.
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    37. Performance of interleukin-27 as a sepsis diagnostic biomarker in critically ill adults. J Crit Care. 2014 Oct; 29(5):718-22. Wong HR, Liu KD, Kangelaris KN, Lahni P, Calfee CS. PMID: 24848949.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    38. Is there still a role for the lung injury score in the era of the Berlin definition ARDS? Ann Intensive Care. 2014 Feb 18; 4(1):4. Kangelaris KN, Calfee CS, May AK, Zhuo H, Matthay MA, Ware LB. PMID: 24533450.
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    39. One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med. 2014 Mar; 40(3):388-96. Wang CY, Calfee CS, Paul DW, Janz DR, May AK, Zhuo H, Bernard GR, Matthay MA, Ware LB, Kangelaris KN. PMID: 24435201.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    40. Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med. 2013 Apr 01; 187(7):736-42. Agrawal A, Matthay MA, Kangelaris KN, Stein J, Chu JC, Imp BM, Cortez A, Abbott J, Liu KD, Calfee CS. PMID: 23328529.
      View in: PubMed   Mentions: 94     Fields:    Translation:Humans
    41. 681. Critical Care Medicine. 2012 Dec 1; 40(12):1-328. Erika Moseson, Hanjing Zhuo, John Stein, Jeff Chu, Michael Matthay, Kirsten Kangelaris, Kathleen Liu, Carolyn Calfee. .
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    42. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest. 2012 May; 141(5):1160-1169. Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA, National Heart, Lung, and Blood Institute ARDS Network . PMID: 22207676.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    43. FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study. Ann Intensive Care. 2011 Jun 14; 1(1):21. Zhang M, Hsu R, Hsu CY, Kordesch K, Nicasio E, Cortez A, McAlpine I, Brady S, Zhuo H, Kangelaris KN, Stein J, Calfee CS, Liu KD. PMID: 21906363.
      View in: PubMed   Mentions:
    44. Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study. J Gen Intern Med. 2010 Oct; 25(10):1030-7. Kangelaris KN, Vittinghoff E, Otte C, Na B, Auerbach AD, Whooley MA. PMID: 20509052.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Genetic Testing Before Anticoagulation? A Systematic Review of Pharmacogenetic Dosing of Warfarin. Journal of General Internal Medicine. 2009 Dec 1; 24(12):1358. Kirsten Neudoerffer Kangelaris, Stephen Bent, Robert L. Nussbaum, David A. Garcia, Jeffrey A. Tice. .
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    46. Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin. J Gen Intern Med. 2009 May; 24(5):656-64. Kangelaris KN, Bent S, Nussbaum RL, Garcia DA, Tice JA. PMID: 19306050.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    47. Clinical implications of founder and recurrent CDH1 mutations in hereditary diffuse gastric cancer. JAMA. 2007 Jun 06; 297(21):2410-1. Kangelaris KN, Gruber SB. PMID: 17545691.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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