Gideon St Helen, PhD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Cigarette Harm Reduction with Scheduled Electronic Cigarette Use
    NIH/NIDA U01DA045519Aug 15, 2018 - Jul 31, 2020
    Role: Co-Investigator
    Clinical Pharmacology of Electronic Cigarettes
    NIH 3R01DA039264-02S1Jun 1, 2016 - May 31, 2017
    Role: Co-Investigator
    Integrated Health, Behavioral and Economic Research on Current and Emerging Tobacco Products
    NIH 9U54HL147127-06Sep 19, 2013 - Jun 30, 2023
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. St Helen G, Benowitz NL, Ahluwalia JS, Tyndale RF, Addo N, Gregorich SE, PĂ©rez-Stable EJ, Cox LS. Black Light Smokers: How Nicotine Intake and Carcinogen Exposure Differ Across Various Biobehavioral Factors. J Natl Med Assoc. 2019 May 10. PMID: 31084916.
      View in: PubMed
    2. Liakoni E, Edwards KC, St Helen G, Nardone N, Dempsey DA, Tyndale RF, Benowitz NL. Effects of Nicotine Metabolic Rate on Withdrawal Symptoms and Response to Cigarette Smoking After Abstinence. Clin Pharmacol Ther. 2019 Mar; 105(3):641-651. PMID: 30242831.
      View in: PubMed
    3. Elias J, Dutra LM, St Helen G, Ling PM. Revolution or redux? Assessing IQOS through a precursor product. Tob Control. 2018 11; 27(Suppl 1):s102-s110. PMID: 30305324.
      View in: PubMed
    4. St Helen G, Jacob Iii P, Nardone N, Benowitz NL. IQOS: examination of Philip Morris International's claim of reduced exposure. Tob Control. 2018 11; 27(Suppl 1):s30-s36. PMID: 30158205.
      View in: PubMed
    5. St Helen G, Eaton DL. Public Health Consequences of e-Cigarette Use. JAMA Intern Med. 2018 Jul 01; 178(7):984-986. PMID: 29801158.
      View in: PubMed
    6. St Helen G, Shahid M, Chu S, Benowitz NL. Impact of e-liquid flavors on e-cigarette vaping behavior. Drug Alcohol Depend. 2018 Aug 01; 189:42-48. PMID: 29879680.
      View in: PubMed
    7. Benowitz NL, Nardone N, Jain S, Dempsey DA, Addo N, St Helen G, Jacob P. Comparison of Urine 4-(Methylnitrosamino)-1-(3)Pyridyl-1-Butanol and Cotinine for Assessment of Active and Passive Smoke Exposure in Urban Adolescents. Cancer Epidemiol Biomarkers Prev. 2018 03; 27(3):254-261. PMID: 29475963.
      View in: PubMed
    8. Velicer C, St Helen G, Glantz SA. Tobacco papers and tobacco industry ties in regulatory toxicology and pharmacology. J Public Health Policy. 2018 Feb; 39(1):34-48. PMID: 29116189.
      View in: PubMed
    9. Havel CM, Benowitz NL, Jacob P, St Helen G. An Electronic Cigarette Vaping Machine for the Characterization of Aerosol Delivery and Composition. Nicotine Tob Res. 2017 Oct 01; 19(10):1224-1231. PMID: 27281605.
      View in: PubMed
    10. Benowitz NL, Jain S, Dempsey DA, Nardone N, Helen GS, Jacob P. Urine Cotinine Screening Detects Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents. Nicotine Tob Res. 2017 Sep 01; 19(9):1048-1054. PMID: 28031377.
      View in: PubMed
    11. St Helen G, Dempsey DA, Havel CM, Jacob P, Benowitz NL. Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. Drug Alcohol Depend. 2017 09 01; 178:391-398. PMID: 28704768.
      View in: PubMed
    12. Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A. Biomarkers of exposure to new and emerging tobacco delivery products. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L425-L452. PMID: 28522563.
      View in: PubMed
    13. Taghavi T, St Helen G, Benowitz NL, Tyndale RF. Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans. Pharmacogenet Genomics. 2017 04; 27(4):143-154. PMID: 28178031.
      View in: PubMed
    14. St Helen G, Ross KC, Dempsey DA, Havel CM, Jacob P, Benowitz NL. Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access. Tob Regul Sci. 2016 Oct; 2(4):363-376. PMID: 28393086.
      View in: PubMed
    15. Benowitz NL, St Helen G, Dempsey DA, Jacob P, Tyndale RF. Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. Pharmacogenet Genomics. 2016 07; 26(7):340-50. PMID: 27035242; PMCID: PMC4892970 [Available on 07/01/17].
    16. Ross KC, Dempsey DA, St Helen G, Delucchi K, Benowitz NL. The Influence of Puff Characteristics, Nicotine Dependence, and Rate of Nicotine Metabolism on Daily Nicotine Exposure in African American Smokers. Cancer Epidemiol Biomarkers Prev. 2016 06; 25(6):936-43. PMID: 27030603; PMCID: PMC4891233 [Available on 06/01/17].
    17. St Helen G, Havel C, Dempsey DA, Jacob P, Benowitz NL. Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. Addiction. 2016 Mar; 111(3):535-44. PMID: 26430813.
      View in: PubMed
    18. St Helen G, Aguilar-Villalobos M, Adetona O, Cassidy B, Bayer CW, Hendry R, Hall DB, Naeher LP. Exposure of pregnant women to cookstove-related household air pollution in urban and periurban Trujillo, Peru. Arch Environ Occup Health. 2015; 70(1):10-8. PMID: 24215174.
      View in: PubMed
    19. St Helen G, Jacob P, Peng M, Dempsey DA, Hammond SK, Benowitz NL. Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2774-82. PMID: 25398951; PMCID: PMC4257856.
    20. St Helen G, Benowitz NL, Dains KM, Havel C, Peng M, Jacob P. Nicotine and carcinogen exposure after water pipe smoking in hookah bars. Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1055-66. PMID: 24836469.
      View in: PubMed
    21. Dempsey DA, St Helen G, Jacob P, Tyndale RF, Benowitz NL. Genetic and pharmacokinetic determinants of response to transdermal nicotine in white, black, and Asian nonsmokers. Clin Pharmacol Ther. 2013 Dec; 94(6):687-94. PMID: 23933970; PMCID: PMC3834081.
    22. St Helen G, Jacob P, Benowitz NL. Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. Nicotine Tob Res. 2013 Nov; 15(11):1939-42. PMID: 23674838; PMCID: PMC3790625.
    23. Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P, Northcross A, Hammond SK, Benowitz NL. Biomarkers of secondhand smoke exposure in automobiles. Tob Control. 2014 Jan; 23(1):51-7. PMID: 23349229; PMCID: PMC3670969.
    24. Benowitz NL, Dempsey D, Tyndale RF, St Helen G, Jacob P. Dose-independent kinetics with low level exposure to nicotine and cotinine. Br J Clin Pharmacol. 2013 Jan; 75(1):277-9. PMID: 22574797; PMCID: PMC3555070.
    25. St Helen G, Dempsey D, Wilson M, Jacob P, Benowitz NL. Racial differences in the relationship between tobacco dependence and nicotine and carcinogen exposure. Addiction. 2013 Mar; 108(3):607-17. PMID: 22971134; PMCID: PMC3553231.
    26. St Helen G, Holland NT, Balmes JR, Hall DB, Bernert JT, Vena JE, Wang JS, Naeher LP. Utility of urinary Clara cell protein (CC16) to demonstrate increased lung epithelial permeability in non-smokers exposed to outdoor secondhand smoke. J Expo Sci Environ Epidemiol. 2013 Mar; 23(2):183-9. PMID: 22805990; PMCID: PMC3507333.
    27. St Helen G, Novalen M, Heitjan DF, Dempsey D, Jacob P, Aziziyeh A, Wing VC, George TP, Tyndale RF, Benowitz NL. Reproducibility of the nicotine metabolite ratio in cigarette smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1105-14. PMID: 22552800; PMCID: PMC3392523.
    28. St Helen G, Bernert JT, Hall DB, Sosnoff CS, Xia Y, Balmes JR, Vena JE, Wang JS, Holland NT, Naeher LP. Exposure to secondhand smoke outside of a bar and a restaurant and tobacco exposure biomarkers in nonsmokers. Environ Health Perspect. 2012 Jul; 120(7):1010-6. PMID: 22484462; PMCID: PMC3404659.
    29. St Helen G, Goniewicz ML, Dempsey D, Wilson M, Jacob P, Benowitz NL. Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers. Chem Res Toxicol. 2012 Apr 16; 25(4):952-64. PMID: 22428611; PMCID: PMC3330130.
    30. St Helen G, Hall DB, Kudon LH, Pearce J, Baptiste S, Ferguson S, Green T, Naeher LP. Particulate matter (PM2.5) and carbon monoxide from secondhand smoke outside bars and restaurants in downtown Athens, Georgia. J Environ Health. 2011 Oct; 74(3):8-17. PMID: 22010328.
      View in: PubMed
    31. Hall JC, Bernert JT, Hall DB, St Helen G, Kudon LH, Naeher LP. Assessment of exposure to secondhand smoke at outdoor bars and family restaurants in Athens, Georgia, using salivary cotinine. J Occup Environ Hyg. 2009 Nov; 6(11):698-704. PMID: 19757294.
      View in: PubMed