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Hal Yee, MD

Title(s)Professor Emeritus, Medicine
SchoolSchool of Medicine
Phone628-206-4808
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship03/1996Gastroenterology/Hepatology
    University of California, San FranciscoResidency 06/1992Internal Medicine
    University of California, Los AngelesPhD06/1990Physiology
    University of California, Los AngelesMD05/1990Medicine
    Brown UniversityAB06/1983Biology

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Adherence and the Economics of Colon Cancer Screening
    NIH/NCI R01CA106773Aug 16, 2006 - Sep 29, 2011
    Role: Principal Investigator
    Regulation of Hepatic Stellate Cell Responses to Injury
    NIH/NIDDK R01DK061532Feb 1, 2003 - Jan 31, 2010
    Role: Principal Investigator
    SIGNAL TRANSDUCTION PATHWAYS IN HEPATIC STELLATE CELLS
    NIH/NIDDK R03DK057532Sep 30, 2000 - Aug 31, 2002
    Role: Principal Investigator
    STIMULUS/CONTRACTION COUPLING IN HEPATIC STELLATE CELLS
    NIH/NIDDK K08DK002450Jul 10, 1997 - Jun 30, 2003
    Role: Principal Investigator
    HEPATIC POTASSIUM CHANNELS--STRUCTURE AND FUNCTION
    NIH/NIDDK F32DK009277Feb 1, 1996
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. eConsult Mental Health: Electronic Referral and Consultation to Integrate Primary Care and Mental Health. J Ambul Care Manage. 2019 Jan/Mar; 42(1):47-50. Leung LB, Benitez CT, Yee HF. PMID: 30499900.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Primary Care Practitioners' Perceptions of Electronic Consult Systems: A Qualitative Analysis. JAMA Intern Med. 2018 06 01; 178(6):782-789. Lee MS, Ray KN, Mehrotra A, Giboney P, Yee HF, Barnett ML. PMID: 29801079.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. The Role of Pioglitazone in the Management of Nonalcoholic Steatohepatitis: Are We There Yet? JAMA Intern Med. 2017 05 01; 177(5):640-641. Yee HF. PMID: 28241265.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Los Angeles Safety-Net Program eConsult System Was Rapidly Adopted And Decreased Wait Times To See Specialists. Health Aff (Millwood). 2017 03 01; 36(3):492-499. Barnett ML, Yee HF, Mehrotra A, Giboney P. PMID: 28264951.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    5. Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults. Mol Biol Rep. 2016 Dec; 43(12):1359-1369. Flores YN, Velázquez-Cruz R, Ramírez P, Bañuelos M, Zhang ZF, Yee HF, Chang SC, Canizales-Quinteros S, Quiterio M, Cabrera-Alvarez G, Patiño N, Salmerón J. PMID: 27752939.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Development and Implementation of Expected Practices to Reduce Inappropriate Variations in Clinical Practice. JAMA. 2016 May 24-31; 315(20):2163-4. Soni SM, Giboney P, Yee HF. PMID: 27218624.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Treatment of Hepatitis C Virus Infection in Real Life. JAMA Intern Med. 2016 Jan; 176(1):73-4. Yee HF. PMID: 26595164.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Access to primary care is associated with better autoimmune hepatitis outcomes in an urban county hospital. BMC Gastroenterol. 2015 Jul 28; 15:91. Kim D, Eshtiaghpour D, Alpern J, Datta A, Eysselein VE, Yee HF. PMID: 26215250.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. eReferral--a new model for integrated care. N Engl J Med. 2013 Jun 27; 368(26):2450-3. Chen AH, Murphy EJ, Yee HF. PMID: 23802515.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    10. Diversity of endoscopy center operations and practice variation across California's safety-net hospital system: a statewide survey. BMC Res Notes. 2013 Jun 15; 6:233. Day LW, Bhuket T, Inadomi JM, Yee HF. PMID: 23767938.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Preconsultation exchange for ambulatory hepatology consultations. Am J Med. 2013 Jun; 126(6):523-8. Sewell JL, Guy J, Kwon A, Chen AH, Yee HF. PMID: 23597797.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Intestinal myofibroblasts produce nitric oxide in response to combinatorial cytokine stimulation. J Cell Physiol. 2013 Mar; 228(3):572-80. Wu J, Chitapanarux T, Chen Y, Soon RK, Yee HF. PMID: 22833357.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Inducible NOS mediates CNP-induced relaxation of intestinal myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 01; 304(7):G673-9. Chen Y, Chitapanarux T, Wu J, Soon RK, Melton AC, Yee HF. PMID: 23348803.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    14. A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice. Hepatology. 2013 Jan; 57(1):339-50. Puche JE, Lee YA, Jiao J, Aloman C, Fiel MI, Muñoz U, Kraus T, Lee T, Yee HF, Friedman SL. PMID: 22961591.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    15. 13-year mortality trends among hospitalized patients with inflammatory bowel disease. BMC Gastroenterol. 2012 Jun 26; 12:79. Sewell JL, Yee HF. PMID: 22734919.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Implementation of an electronic referral system for outpatient specialty care. AMIA Annu Symp Proc. 2011; 2011:1337-46. Straus SG, Chen AH, Yee H, Kushel MB, Bell DS. PMID: 22195195.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    17. From the bedside to the community: comparative effectiveness, health services, and implementation research. Hepatology. 2011 Feb; 53(2):673-7. Rongey C, Yee HF. PMID: 21274887.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Improving primary care-specialty care communication: lessons from San Francisco's safety net: comment on "Referral and consultation communication between primary care and specialist physicians". Arch Intern Med. 2011 Jan 10; 171(1):65-7. Chen AH, Yee HF. PMID: 21220663.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. The patient-centered medical home neighbor: A subspecialty physician's view. Ann Intern Med. 2011 Jan 04; 154(1):63-4. Yee HF. PMID: 21200042.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    20. Formal patient education improves patient knowledge of hepatitis C in vulnerable populations. Dig Dis Sci. 2011 Jan; 56(1):213-9. Surjadi M, Torruellas C, Ayala C, Yee HF, Khalili M. PMID: 20972850.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    21. Race and inflammatory bowel disease in an urban healthcare system. Dig Dis Sci. 2010 Dec; 55(12):3479-87. Sewell JL, Inadomi JM, Yee HF. PMID: 20936350.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    22. HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. J Virol. 2010 Nov; 84(21):11020-9. Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 20719952.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    23. Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers. J Virol. 2010 Oct; 84(19):10354-65. Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 20668079.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    24. Evaluating electronic referrals for specialty care at a public hospital. J Gen Intern Med. 2010 Oct; 25(10):1123-8. Kim-Hwang JE, Chen AH, Bell DS, Guzman D, Yee HF, Kushel MB. PMID: 20512531.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    25. Practice profile. A safety-net system gains efficiencies through 'eReferrals' to specialists. Health Aff (Millwood). 2010 May; 29(5):969-71. Chen AH, Kushel MB, Grumbach K, Yee HF. PMID: 20439891.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    26. Hospitalizations are increasing among minority patients with Crohn's disease and ulcerative colitis. Inflamm Bowel Dis. 2010 Feb; 16(2):204-7. Sewell JL, Yee HF, Inadomi JM. PMID: 19575353.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    27. Healthcare reform with a safety net: lessons from San Francisco. Am J Manag Care. 2009 Oct; 15(10):747-50. Bindman AB, Chen A, Fraser JS, Yee HF, Ofman D. PMID: 19845426.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    28. Non-English speakers attend gastroenterology clinic appointments at higher rates than English speakers in a vulnerable patient population. J Clin Gastroenterol. 2009 Aug; 43(7):652-60. Sewell JL, Kushel MB, Inadomi JM, Yee HF. PMID: 19169147.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Health disparities in liver disease: Time to take notice and take action. Hepatology. 2009 Jul; 50(1):309-13. Guy J, Yee HF. PMID: 19554619.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    30. Improving the primary care-specialty care interface: getting from here to there. Arch Intern Med. 2009 Jun 08; 169(11):1024-6. Chen AH, Yee HF. PMID: 19506170.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    31. Understanding liver health using the National Center for Health Statistics. Dig Dis Sci. 2009 Nov; 54(11):2325-9. Somsouk M, Yee HF, Biggins SW. PMID: 19424799.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Not perfect, but better: primary care providers' experiences with electronic referrals in a safety net health system. J Gen Intern Med. 2009 May; 24(5):614-9. Kim Y, Chen AH, Keith E, Yee HF, Kushel MB. PMID: 19308334.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    33. Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood. 2009 Apr 23; 113(17):3978-89. Ferre AL, Hunt PW, Critchfield JW, Young DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 19109229.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    34. Stellate cell contraction: role, regulation, and potential therapeutic target. Clin Liver Dis. 2008 Nov; 12(4):791-803, viii. Soon RK, Yee HF. PMID: 18984467.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    35. Risk factors for chronic liver disease in Blacks, Mexican Americans, and Whites in the United States: results from NHANES IV, 1999-2004. Am J Gastroenterol. 2008 Sep; 103(9):2231-8. Flores YN, Yee HF, Leng M, Escarce JJ, Bastani R, Salmerón J, Morales LS. PMID: 18671818.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    36. In search of an ideal biomarker for nonalcoholic fatty liver disease. Am J Gastroenterol. 2008 Jun; 103(6):1380-2. Bambha K, Yee HF. PMID: 18510615.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Focal adhesion disassembly is an essential early event in hepatic stellate cell chemotaxis. Am J Physiol Gastrointest Liver Physiol. 2007 Dec; 293(6):G1272-80. Melton AC, Soon RK, Park JG, Martinez L, Dehart GW, Yee HF. PMID: 17947456.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    38. A cost-identification analysis of screening and surveillance of hepatitis C infection in a prospective cohort of dialysis patients. Dig Dis Sci. 2008 Apr; 53(4):1093-9. Somsouk M, Langfield DE, Inadomi JM, Yee HF. PMID: 17934829.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    39. Hepatic stellate cell protrusions couple platelet-derived growth factor-BB to chemotaxis. Hepatology. 2007 Jun; 45(6):1446-53. Melton AC, Yee HF. PMID: 17465006.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    40. RhoA-kinase and myosin II are required for the maintenance of growth cone polarity and guidance by nerve growth factor. J Neurobiol. 2006 Jul; 66(8):847-67. Loudon RP, Silver LD, Yee HF, Gallo G. PMID: 16673385.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    41. [Ca2+]i-independent contractile force generation by rat hepatic stellate cells in response to endothelin-1. Am J Physiol Gastrointest Liver Physiol. 2006 Jan; 290(1):G7-13. Melton AC, Datta A, Yee HF. PMID: 16123199.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    42. Is weight reduction an effective therapy for nonalcoholic fatty liver? A systematic review. Am J Med. 2003 Nov; 115(7):554-9. Wang RT, Koretz RL, Yee HF. PMID: 14599635.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    43. C-type natriuretic peptide induces human colonic myofibroblast relaxation. Am J Physiol Gastrointest Liver Physiol. 2004 Jan; 286(1):G31-6. Chitapanarux T, Chen SL, Lee H, Melton AC, Yee HF. PMID: 12958024.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    44. Rho and p38 MAP kinase signaling pathways mediate LPA-stimulated hepatic myofibroblast migration. J Biomed Sci. 2003 May-Jun; 10(3):352-8. Tangkijvanich P, Melton AC, Santiskulvong C, Yee HF. PMID: 12711863.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    45. Platelet-derived growth factor-BB and lysophosphatidic acid distinctly regulate hepatic myofibroblast migration through focal adhesion kinase. Exp Cell Res. 2002 Nov 15; 281(1):140-7. Tangkijvanich P, Melton AC, Chitapanarux T, Han J, Yee HF. PMID: 12441137.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    46. Myosin mediates contractile force generation by hepatic stellate cells in response to endothelin-1. J Biomed Sci. 2002 Nov-Dec; 9(6 Pt 2):607-12. Saab S, Tam S, Tran Bi, Melton A, Tangkijvanich P, Wong H, Yee H. PMID: 12432226.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    47. Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility. J Cell Biol. 2002 Sep 30; 158(7):1219-28. Gallo G, Yee HF, Letourneau PC. PMID: 12356866.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    48. Comparison of the cost and effectiveness of two strategies for maintaining hepatitis B immunity in hemodialysis patients. Vaccine. 2002 Aug 19; 20(25-26):3230-5. Saab S, Weston SR, Ly D, Brezina M, Yee HF, Han SH, Gitnick G. PMID: 12163275.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    49. p38 MAP kinase mediates platelet-derived growth factor-stimulated migration of hepatic myofibroblasts. J Cell Physiol. 2002 Jun; 191(3):351-61. Tangkijvanich P, Santiskulvong C, Melton AC, Rozengurt E, Yee HF. PMID: 12012331.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    50. Vasopressin-mediated mitogenic signaling in intestinal epithelial cells. Am J Physiol Cell Physiol. 2002 Mar; 282(3):C434-50. Chiu T, Wu SS, Santiskulvong C, Tangkijvanich P, Yee HF, Rozengurt E. PMID: 11832328.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    51. Hepatitis B surface antigenemia in chronic hemodialysis patients: effect of hepatitis B immunization. Am J Gastroenterol. 2002 Jan; 97(1):138-41. Ly D, Yee HF, Brezina M, Martin P, Gitnick G, Saab S. PMID: 11808938.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    52. Cirrhosis--can we reverse hepatic fibrosis? Eur J Surg Suppl. 2002; (587):100-12. Tangkijvanich P, Yee HF. PMID: 16144208.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    53. Visualization of internalization and recycling of the gastrin releasing peptide receptor-green fluorescent protein chimera expressed in epithelial cells. Receptors Channels. 1998; 6(3):201-12. Slice LW, Yee HF, Walsh JH. PMID: 10100328.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    54. Effects of neuraminidase on cellular calcium and contraction in cultured cardiac myocytes. J Mol Cell Cardiol. 1991 Feb; 23(2):175-85. Yee HF, Kuwata JH, Langer GA. PMID: 2067026.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    55. Neuraminidase selectively enhances transient Ca2+ current in cardiac myocytes. Am J Physiol. 1989 Jun; 256(6 Pt 1):C1267-72. Yee HF, Weiss JN, Langer GA. PMID: 2544097.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
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