Idelisse Ortiz Torres, MD, PhD
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Title(s) | Resident, Neurology |
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School | School of Medicine |
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Phone | 415-353-2273 |
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vCard | Download vCard |
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Title(s) | UCSF Weill Institute for Neurosciences |
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Biography UCSF, San Francisco | PhD | 2015 | Chemistry and Chemical Biology | Icahn School of Medicine at Mount Sinai, New York | MD | 2019 | | University of Puerto Rico, Rio Piedras, PR | BS | 2008 | Chemistry |
Bibliographic
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Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, Montgomery SE, Loh YE, Labonté B, Conkey A, Symonds AE, Neve RL, Turecki G, Maze I, Dong Y, Zhang B, Shen L, Bagot RC, Nestler EJ. Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nat Neurosci. 2019 09; 22(9):1413-1423. PMID: 31427770.
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Longbotham JE, Chio CM, Dharmarajan V, Trnka MJ, Torres IO, Goswami D, Ruiz K, Burlingame AL, Griffin PR, Fujimori DG. Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling. Nat Commun. 2019 01 09; 10(1):94. PMID: 30626866.
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Korczynska M, Le DD, Younger N, Gregori-Puigjané E, Tumber A, Krojer T, Velupillai S, Gileadi C, Nowak RP, Iwasa E, Pollock SB, Ortiz Torres I, Oppermann U, Shoichet BK, Fujimori DG. Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors. J Med Chem. 2016 Feb 25; 59(4):1580-98. PMID: 26699912.
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Torres IO, Fujimori DG. Functional coupling between writers, erasers and readers of histone and DNA methylation. Curr Opin Struct Biol. 2015 Dec; 35:68-75. PMID: 26496625.
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Torres IO, Kuchenbecker KM, Nnadi CI, Fletterick RJ, Kelly MJ, Fujimori DG. Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism. Nat Commun. 2015 Feb 17; 6:6204. PMID: 25686748.
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Shiau C, Trnka MJ, Bozicevic A, Ortiz Torres I, Al-Sady B, Burlingame AL, Narlikar GJ, Fujimori DG. Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase. Chem Biol. 2013 Apr 18; 20(4):494-9. PMID: 23601638.
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Martinez CJ, Kim JW, Ye C, Ortiz I, Rowat AC, Marquez M, Weitz D. A microfluidic approach to encapsulate living cells in uniform alginate hydrogel microparticles. Macromol Biosci. 2012 Jul; 12(7):946-51. PMID: 22311460.
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Jiménez-Romero C, Ortiz I, Vicente J, Vera B, Rodríguez AD, Nam S, Jove R. Bioactive Cycloperoxides Isolated from the Puerto Rican Sponge Plakortis halichondrioides. J Nat Prod. 2010 Oct 22; 73(10):1694-700. PMID: 20923180.
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