Geeta Narlikar, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St, #N412F
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California , San Francisco2021Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Tetrad: Genetics, Cell Biology, Biochemistry and Molecular Biology Training Grant
    NIH T32GM139786Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Modulation and functional characterization of protein condensation in chromatin organization
    NIH U01DK127421Sep 15, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    ATP-dependent and independent mechanisms of regulating chromatin states
    NIH R35GM127020May 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Mechanistic dissection of HP1 mediated heterochromatin
    NIH R01GM108455May 1, 2014 - Apr 30, 2018
    Role: Principal Investigator
    Mechanistic Analysis of Chromatin Remodeling
    NIH R01GM073767Apr 1, 2005 - Nov 30, 2018
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    Cell Biology, Genetics, and Biochemistry Training Grant
    NIH T32GM007810Jul 1, 1979 - Jun 30, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nat Commun. 2024 Mar 12; 15(1):2225. Chio US, Palovcak E, Smith AAA, Autzen H, Muñoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y. PMID: 38472177; PMCID: PMC10933330.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Hexasomal particles: consequence or also consequential? Curr Opin Genet Dev. 2024 Apr; 85:102163. Kaur U, Muñoz EN, Narlikar GJ. PMID: 38412564.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. Understanding how genetically encoded tags affect phase separation by Heterochromatin Protein HP1α. bioRxiv. 2023 Dec 05. Zhou ZK, Narlikar GJ. PMID: 38106110; PMCID: PMC10723358.
      View in: PubMed   Mentions:
    4. Nucleosome density shapes kilobase-scale regulation by a mammalian chromatin remodeler. Nat Struct Mol Biol. 2023 10; 30(10):1571-1581. Abdulhay NJ, Hsieh LJ, McNally CP, Ostrowski MS, Moore CM, Ketavarapu M, Kasinathan S, Nanda AS, Wu K, Chio US, Zhou Z, Goodarzi H, Narlikar GJ, Ramani V. PMID: 37696956; PMCID: PMC10584690.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    5. Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Mol Cell. 2023 08 17; 83(16):2872-2883.e7. Abini-Agbomson S, Gretarsson K, Shih RM, Hsieh L, Lou T, De Ioannes P, Vasilyev N, Lee R, Wang M, Simon MD, Armache JP, Nudler E, Narlikar G, Liu S, Lu C, Armache KJ. PMID: 37595555.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science. 2023 07 21; 381(6655):319-324. Wu H, Muñoz EN, Hsieh LJ, Chio US, Gourdet MA, Narlikar GJ, Cheng Y. PMID: 37384669; PMCID: PMC10480058.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. bioRxiv. 2023 Jun 20. Chio US, Palovcak E, Autzen AAA, Autzen HE, Muñoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y. PMID: 37546986; PMCID: PMC10402172.
      View in: PubMed   Mentions:
    8. In diverse conditions, intrinsic chromatin condensates have liquid-like material properties. Proc Natl Acad Sci U S A. 2023 05 02; 120(18):e2218085120. Gibson BA, Blaukopf C, Lou T, Chen L, Doolittle LK, Finkelstein I, Narlikar GJ, Gerlich DW, Rosen MK. PMID: 37094140; PMCID: PMC10161002.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    9. Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. bioRxiv. 2023 Mar 19. Abini-Agbomson S, Gretarsson K, Shih RM, Hsieh L, Lou T, De Ioannes P, Vasilyev N, Lee R, Wang M, Simon M, Armache JP, Nudler E, Narlikar G, Liu S, Lu C, Armache KJ. PMID: 36993485; PMCID: PMC10055266.
      View in: PubMed   Mentions:
    10. Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells. Nat Commun. 2022 06 20; 13(1):3525. Novo CL, Wong EV, Hockings C, Poudel C, Sheekey E, Wiese M, Okkenhaug H, Boulton SJ, Basu S, Walker S, Kaminski Schierle GS, Narlikar GJ, Rugg-Gunn PJ. PMID: 35725842; PMCID: PMC9209518.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    11. ATP Hydrolysis Coordinates the Activities of Two Motors in a Dimeric Chromatin Remodeling Enzyme. J Mol Biol. 2022 07 30; 434(14):167653. Johnson SL, Narlikar GJ. PMID: 35659534.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    12. A hexasome is the preferred substrate for the INO80 chromatin remodeling complex, allowing versatility of function. Mol Cell. 2022 06 02; 82(11):2098-2112.e4. Hsieh LJ, Gourdet MA, Moore CM, Muñoz EN, Gamarra N, Ramani V, Narlikar GJ. PMID: 35597239; PMCID: PMC9351570.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    13. A hexasome is the preferred substrate of the INO80 chromatin remodeling complex. Biophysical Journal. 2022 Feb 1; 121(3):6a. Narlikar NG, Hsieh HL, Gourdet GM, Ramani RV. .
      View in: Publisher Site   Mentions:
    14. Histone dynamics play a critical role in SNF2h-mediated nucleosome sliding. Nat Struct Mol Biol. 2021 07; 28(7):548-551. Gamarra N, Narlikar GJ. PMID: 34226739; PMCID: PMC9040563.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    15. Generation and Biochemical Characterization of Phase-Separated Droplets Formed by Nucleic Acid Binding Proteins: Using HP1 as a Model System. Curr Protoc. 2021 May; 1(5):e109. Sanulli S, Narlikar GJ. PMID: 33950570; PMCID: PMC8103610.
      View in: PubMed   Mentions: 5     Fields:    
    16. Is transcriptional regulation just going through a phase? Mol Cell. 2021 04 15; 81(8):1579-1585. Narlikar GJ, Myong S, Larson D, Maeshima K, Francis N, Rippe K, Sabari B, Strader L, Tjian R. PMID: 33861943.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    17. HP1 proteins compact DNA into mechanically and positionally stable phase separated domains. Elife. 2021 03 04; 10. Keenen MM, Brown D, Brennan LD, Renger R, Khoo H, Carlson CR, Huang B, Grill SW, Narlikar GJ, Redding S. PMID: 33661100; PMCID: PMC7932698.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    18. Collaboration through chromatin: motors of transcription and chromatin structure. J Mol Biol. 2021 07 09; 433(14):166876. Gamarra N, Narlikar GJ. PMID: 33556407; PMCID: PMC8989640.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    19. Massively multiplex single-molecule oligonucleosome footprinting. Elife. 2020 12 02; 9. Abdulhay NJ, McNally CP, Hsieh LJ, Kasinathan S, Keith A, Estes LS, Karimzadeh M, Underwood JG, Goodarzi H, Narlikar GJ, Ramani V. PMID: 33263279; PMCID: PMC7735760.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    20. Enzymatic Reactions inside Biological Condensates. J Mol Biol. 2021 06 11; 433(12):166624. Zhang Y, Narlikar GJ, Kutateladze TG. PMID: 32805219; PMCID: PMC9089403.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    21. Biophysical Properties of HP1-Mediated Heterochromatin. Cold Spring Harb Symp Quant Biol. 2019; 84:217-225. Sanulli S, Gross JD, Narlikar GJ. PMID: 32493764; PMCID: PMC9128075.
      View in: PubMed   Mentions: 8     Fields:    
    22. ATP Hydrolysis by the SNF2 Domain of Dnmt5 Is Coupled to Both Specific Recognition and Modification of Hemimethylated DNA. Mol Cell. 2020 07 02; 79(1):127-139.e4. Dumesic PA, Stoddard CI, Catania S, Narlikar GJ, Madhani HD. PMID: 32437639; PMCID: PMC7335330.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    23. Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage. Sci Adv. 2020 03; 6(12):eaaz9115. Srinivasan R, Nady N, Arora N, Hsieh LJ, Swigut T, Narlikar GJ, Wossidlo M, Wysocka J. PMID: 32219172; PMCID: PMC7083622.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    24. Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase. Cell. 2020 Feb 20; 180(4):816. Catania S, Dumesic PA, Pimentel H, Nasif A, Stoddard CI, Burke JE, Diedrich JK, Cooke S, Shea T, Gienger E, Lintner R, Yates JR, Hajkova P, Narlikar GJ, Cuomo CA, Pritchard JK, Madhani HD. PMID: 32084344; PMCID: PMC7201975.
      View in: PubMed   Mentions: 5     Fields:    
    25. Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase. Cell. 2020 01 23; 180(2):263-277.e20. Catania S, Dumesic PA, Pimentel H, Nasif A, Stoddard CI, Burke JE, Diedrich JK, Cook S, Shea T, Geinger E, Lintner R, Yates JR, Hajkova P, Narlikar GJ, Cuomo CA, Pritchard JK, Madhani HD. PMID: 31955845; PMCID: PMC7197499.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    26. Topical collection on Chromatin Biology and Epigenetics. J Biosci. 2020; 45. Narlikar G, Galande S. PMID: 31965979.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    27. Phase-separation in chromatin organization. J Biosci. 2020; 45. Narlikar GJ. PMID: 31965983; PMCID: PMC9107952.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    28. HP1 reshapes nucleosome core to promote phase separation of heterochromatin. Nature. 2019 11; 575(7782):390-394. Sanulli S, Trnka MJ, Dharmarajan V, Tibble RW, Pascal BD, Burlingame AL, Griffin PR, Gross JD, Narlikar GJ. PMID: 31618757; PMCID: PMC7039410.
      View in: PubMed   Mentions: 202     Fields:    Translation:AnimalsCells
    29. Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase? Development. 2019 09 25; 146(19). Mir M, Bickmore W, Furlong EEM, Narlikar G. PMID: 31554625; PMCID: PMC6803379.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    30. Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome. Elife. 2019 06 18; 8. Armache JP, Gamarra N, Johnson SL, Leonard JD, Wu S, Narlikar GJ, Cheng Y. PMID: 31210637; PMCID: PMC6611695.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    31. Ion counting demonstrates a high electrostatic field generated by the nucleosome. Elife. 2019 06 11; 8. Gebala M, Johnson SL, Narlikar GJ, Herschlag D. PMID: 31184587; PMCID: PMC6584128.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    32. The Role of Phase-Separation in Heterochromatin. Biophysical Journal. 2019 Feb 1; 116(3):161a. Narlikar NG, Sanulli SS, Gross GJ, Griffin GP, Trnka TM. .
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    33. A Nucleosome Bridging Mechanism for Activation of a Maintenance DNA Methyltransferase. Mol Cell. 2019 01 03; 73(1):73-83.e6. Stoddard CI, Feng S, Campbell MG, Liu W, Wang H, Zhong X, Bernatavichute Y, Cheng Y, Jacobsen SE, Narlikar GJ. PMID: 30415948; PMCID: PMC6407616.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    34. Visualization and Quantitation of Phase-Separated Droplet Formation by Human HP1α. Methods Enzymol. 2018; 611:51-66. Keenen MM, Larson AG, Narlikar GJ. PMID: 30471698; PMCID: PMC8989641.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    35. The Role of Phase Separation in Heterochromatin Formation, Function, and Regulation. Biochemistry. 2018 05 01; 57(17):2540-2548. Larson AG, Narlikar GJ. PMID: 29644850; PMCID: PMC9084486.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    36. The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h. Elife. 2018 04 17; 7. Gamarra N, Johnson SL, Trnka MJ, Burlingame AL, Narlikar GJ. PMID: 29664398; PMCID: PMC5976439.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    37. The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding. Mol Cell. 2018 02 15; 69(4):677-688.e9. Zhou CY, Johnson SL, Lee LJ, Longhurst AD, Beckwith SL, Johnson MJ, Morrison AJ, Narlikar GJ. PMID: 29452642; PMCID: PMC5897057.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    38. Dissecting the Mechanism of HP1 Mediated Chromatin Compaction via Single Molecule DNA Curtains. Biophysical Journal. 2018 Feb 1; 114(3):30a. Keenen KM, Larson LA, Narlikar NG, Redding RS. .
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    39. Biochemical Basis for Distinct Roles of the Heterochromatin Proteins Swi6 and Chp2. J Mol Biol. 2017 11 24; 429(23):3666-3677. Isaac RS, Sanulli S, Tibble R, Hornsby M, Ravalin M, Craik CS, Gross JD, Narlikar GJ. PMID: 28942089; PMCID: PMC5693750.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    40. Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin. Nature. 2017 07 13; 547(7662):236-240. Larson AG, Elnatan D, Keenen MM, Trnka MJ, Johnston JB, Burlingame AL, Agard DA, Redding S, Narlikar GJ. PMID: 28636604; PMCID: PMC5606208.
      View in: PubMed   Mentions: 737     Fields:    Translation:HumansAnimalsCells
    41. Regulation of Rvb1/Rvb2 by a Domain within the INO80 Chromatin Remodeling Complex Implicates the Yeast Rvbs as Protein Assembly Chaperones. Cell Rep. 2017 06 06; 19(10):2033-2044. Zhou CY, Stoddard CI, Johnston JB, Trnka MJ, Echeverria I, Palovcak E, Sali A, Burlingame AL, Cheng Y, Narlikar GJ. PMID: 28591576; PMCID: PMC5564220.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    42. Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler. Science. 2017 01 20; 355(6322). Sinha KK, Gross JD, Narlikar GJ. PMID: 28104838; PMCID: PMC5656449.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    43. Mechanisms of ATP-Dependent Chromatin Remodeling Motors. Annu Rev Biophys. 2016 07 05; 45:153-81. Zhou CY, Johnson SL, Gamarra NI, Narlikar GJ. PMID: 27391925; PMCID: PMC9157391.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    44. Nucleosome breathing and remodeling constrain CRISPR-Cas9 function. Elife. 2016 04 28; 5. Isaac RS, Jiang F, Doudna JA, Lim WA, Narlikar GJ, Almeida R. PMID: 27130520; PMCID: PMC4880442.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    45. Analysis of Nucleosome Sliding by ATP-Dependent Chromatin Remodeling Enzymes. Methods Enzymol. 2016; 573:119-35. Zhou CY, Narlikar GJ. PMID: 27372751.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    46. Single-Molecule Mechanistic Dissection of a Chromatin Remodeling Motor. Biophysical Journal. 2016 Feb 1; 110(3):67a-68a. Johnson JS, Gamarra GN, Johnson JM, Narlikar NG. .
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    47. A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation. PLoS One. 2015; 10(5):e0126420. Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, Fairman R, Finn RM, Fischle W, de la Torre JG, Gor J, Gustafsson H, Hall D, Harding SE, Cifre JG, Herr AB, Howell EE, Isaac RS, Jao SC, Jose D, Kim SJ, Kokona B, Kornblatt JA, Kosek D, Krayukhina E, Krzizike D, Kusznir EA, Kwon H, Larson A, Laue TM, Le Roy A, Leech AP, Lilie H, Luger K, Luque-Ortega JR, Ma J, May CA, Maynard EL, Modrak-Wojcik A, Mok YF, Mücke N, Nagel-Steger L, Narlikar GJ, Noda M, Nourse A, Obsil T, Park CK, Park JK, Pawelek PD, Perdue EE, Perkins SJ, Perugini MA, Peterson CL, Peverelli MG, Piszczek G, Prag G, Prevelige PE, Raynal BD, Rezabkova L, Richter K, Ringel AE, Rosenberg R, Rowe AJ, Rufer AC, Scott DJ, Seravalli JG, Solovyova AS, Song R, Staunton D, Stoddard C, Stott K, Strauss HM, Streicher WW, Sumida JP, Swygert SG, Szczepanowski RH, Tessmer I, Toth RT, Tripathy A, Uchiyama S, Uebel SF, Unzai S, Gruber AV, von Hippel PH, Wandrey C, Wang SH, Weitzel SE, Wielgus-Kutrowska B, Wolberger C, Wolff M, Wright E, Wu YS, Wubben JM, Schuck P. PMID: 25997164; PMCID: PMC4440767.
      View in: PubMed   Mentions: 46     Fields:    
    48. A nucleotide-driven switch regulates flanking DNA length sensing by a dimeric chromatin remodeler. Mol Cell. 2015 Mar 05; 57(5):850-859. Leonard JD, Narlikar GJ. PMID: 25684208; PMCID: PMC4355161.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    49. The histone H4 tail regulates the conformation of the ATP-binding pocket in the SNF2h chromatin remodeling enzyme. J Mol Biol. 2014 May 15; 426(10):2034-44. Racki LR, Naber N, Pate E, Leonard JD, Cooke R, Narlikar GJ. PMID: 24607692; PMCID: PMC4059342.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    50. Mechanisms of functional promiscuity by HP1 proteins. Trends Cell Biol. 2014 Jun; 24(6):377-86. Canzio D, Larson A, Narlikar GJ. PMID: 24618358; PMCID: PMC4077871.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    51. The Mechanism of Nucleosome Spacing by a Dimeric Chromatin Remodeling Enzyme. Biophysical Journal. 2014 Jan 1; 106(2):69a-70a. Leonard LJ, Armache AJ, Naber NN, Wu WS, Pate PE, Cooke CR, Cheng CY, Narlikar NG. .
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    52. Mechanism of Nucleosome Remodeling by INO80 from S. Cerevisiae. Biophysical Journal. 2014 Jan 1; 106(2):76a. Zhou ZC, Narlikar NG. .
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    53. Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes. Cell. 2013 Aug 01; 154(3):490-503. Narlikar GJ, Sundaramoorthy R, Owen-Hughes T. PMID: 23911317; PMCID: PMC3781322.
      View in: PubMed   Mentions: 303     Fields:    Translation:HumansAnimalsCells
    54. Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread. Mol Cell. 2013 Jul 11; 51(1):80-91. Al-Sady B, Madhani HD, Narlikar GJ. PMID: 23849629; PMCID: PMC3752401.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    55. Abstract IA23: Functional and structural studies of HP1 heterochromatin. DNA Methylation. 2013 Jul 1; ia23-ia23. Canzio CD, Liang LM, Naber NN, Larson LA, Marina MD, Garcia GJ, Madhani MH, Cooke CR, Schuck SP, Cheng CY, Narlikar NG. .
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    56. Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase. Chem Biol. 2013 Apr 18; 20(4):494-9. Shiau C, Trnka MJ, Bozicevic A, Ortiz Torres I, Al-Sady B, Burlingame AL, Narlikar GJ, Fujimori DG. PMID: 23601638; PMCID: PMC3704229.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    57. Mechanistic Analysis of HP1 heterochromatin assembly. The FASEB Journal. 2013 Apr 1; 27:456.3-456.3. Narlikar NG, Canzio CD, Liao LM, Naber NN, Pate PE, Larson LA, Wu WS, Cooke CR, Schuck SP, Cheng CY. .
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    58. A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature. 2013 Apr 18; 496(7445):377-81. Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ. PMID: 23485968; PMCID: PMC3907283.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    59. Ers1 links HP1 to RNAi. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11258-63. Rougemaille M, Braun S, Coyle S, Dumesic PA, Garcia JF, Isaac RS, Libri D, Narlikar GJ, Madhani HD. PMID: 22733737; PMCID: PMC3396509.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    60. Analysis of changes in nucleosome conformation using fluorescence resonance energy transfer. Methods Mol Biol. 2012; 833:337-49. Shahian T, Narlikar GJ. PMID: 22183603.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    61. Mechanisms of Chromatin Remodeling Motors. Biophysical Journal. 2012 Jan 1; 102(3):428a. Narlikar NG, Leonard LJ, Racki RL, Naber NN, Cooke CR, Cheng CY. .
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    62. Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution. Science. 2011 Nov 18; 334(6058):977-82. Armache KJ, Garlick JD, Canzio D, Narlikar GJ, Kingston RE. PMID: 22096199; PMCID: PMC4098850.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    63. Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress. Proc Natl Acad Sci U S A. 2011 Jun 28; 108(26):10620-5. Charles GM, Chen C, Shih SC, Collins SR, Beltrao P, Zhang X, Sharma T, Tan S, Burlingame AL, Krogan NJ, Madhani HD, Narlikar GJ. PMID: 21673141; PMCID: PMC3127919.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    64. EPR Spectroscopy Shows That the H4 Tail of the Nucleosome Influences the Nucleotide-Binding Pocket of Acf. Biophysical Journal. 2011 Feb 1; 100(3):69a. Racki RL, Naber NN, Cooke CR, Narlikar NG. .
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    65. Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Mol Cell. 2011 Jan 07; 41(1):67-81. Canzio D, Chang EY, Shankar S, Kuchenbecker KM, Simon MD, Madhani HD, Narlikar GJ, Al-Sady B. PMID: 21211724; PMCID: PMC3752404.
      View in: PubMed   Mentions: 166     Fields:    Translation:Cells
    66. The ATP-dependent remodeler RSC transfers histone dimers and octamers through the rapid formation of an unstable encounter intermediate. Biochemistry. 2010 Nov 16; 49(45):9882-90. Rowe CE, Narlikar GJ. PMID: 20853842; PMCID: PMC2976819.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    67. A proposal for kinetic proof reading by ISWI family chromatin remodeling motors. Curr Opin Chem Biol. 2010 Oct; 14(5):660-5. Narlikar GJ. PMID: 20833099; PMCID: PMC2953606.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    68. The Chromatin-Remodeling Complex ACF Functions as a Dimeric Motor to Space Nucleosomes. Biophysical Journal. 2010 Jan 1; 98(3):476a. Racki RL, Narlikar NG, Cooke CR, Naber NN, Purcell PT, Yang YJ, Cheng CY, Acevedo AA, Partensky PP. .
      View in: Publisher Site   Mentions:
    69. The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes. Nature. 2009 Dec 24; 462(7276):1016-21. Racki LR, Yang JG, Naber N, Partensky PD, Acevedo A, Purcell TJ, Cooke R, Cheng Y, Narlikar GJ. PMID: 20033039; PMCID: PMC2869534.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    70. Dynamics of nucleosome remodelling by individual ACF complexes. Nature. 2009 Dec 24; 462(7276):1022-7. Blosser TR, Yang JG, Stone MD, Narlikar GJ, Zhuang X. PMID: 20033040; PMCID: PMC2835771.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    71. Chromatin remodelers act globally, sequence positions nucleosomes locally. J Mol Biol. 2009 Aug 07; 391(1):12-25. Partensky PD, Narlikar GJ. PMID: 19450608; PMCID: PMC2813840.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    72. Mechanisms of ATP-dependent Chromatin Remodeling Enzymes. The FASEB Journal. 2009 Apr 1; 23:325.2-325.2. Narlikar NG, Racki RL, Yang YJ, Cheng CY, Naber NN, Cooke CR. .
      View in: Publisher Site   Mentions:
    73. Nucleosome Sliding by ACF is Processive and Bidirectional. Biophysical Journal. 2009 Feb 1; 96(3):566a. Blosser BT, Stone SM, Yang YJ, Narlikar NG, Zhuang ZX. .
      View in: Publisher Site   Mentions:
    74. MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF. Biochemistry. 2008 Dec 23; 47(51):13726-32. Chang EY, Ferreira H, Somers J, Nusinow DA, Owen-Hughes T, Narlikar GJ. PMID: 19035833; PMCID: PMC3428728.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    75. Epigenomics: a roadmap, but to where? Science. 2008 Oct 03; 322(5898):43-4. Madhani HD, Francis NJ, Kingston RE, Kornberg RD, Moazed D, Narlikar GJ, Panning B, Struhl K. PMID: 18832628; PMCID: PMC4479142.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    76. ATP-dependent chromatin remodeling enzymes: two heads are not better, just different. Curr Opin Genet Dev. 2008 Apr; 18(2):137-44. Racki LR, Narlikar GJ. PMID: 18339542; PMCID: PMC2494867.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    77. Mechanism of the ATP-dependent chromatin remodeling complex ACF. The FASEB Journal. 2007 Apr 1; 21(5):a39-a39. Narlikar NG, Yang YJ, Racki RL, Partensky PP. .
      View in: Publisher Site   Mentions:
    78. The site-specific installation of methyl-lysine analogs into recombinant histones. Cell. 2007 Mar 09; 128(5):1003-12. Simon MD, Chu F, Racki LR, de la Cruz CC, Burlingame AL, Panning B, Narlikar GJ, Shokat KM. PMID: 17350582; PMCID: PMC2932701.
      View in: PubMed   Mentions: 244     Fields:    Translation:AnimalsCells
    79. FRET-based methods to study ATP-dependent changes in chromatin structure. Methods. 2007 Mar; 41(3):291-5. Yang JG, Narlikar GJ. PMID: 17309839; PMCID: PMC1941662.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    80. The chromatin-remodeling enzyme ACF is an ATP-dependent DNA length sensor that regulates nucleosome spacing. Nat Struct Mol Biol. 2006 Dec; 13(12):1078-83. Yang JG, Madrid TS, Sevastopoulos E, Narlikar GJ. PMID: 17099699.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    81. Human ACF1 alters the remodeling strategy of SNF2h. J Biol Chem. 2006 Sep 29; 281(39):28636-47. He X, Fan HY, Narlikar GJ, Kingston RE. PMID: 16877760.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    82. Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region. Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42):15012-7. Mahajan MC, Narlikar GJ, Boyapaty G, Kingston RE, Weissman SM. PMID: 16217013; PMCID: PMC1257739.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    83. Noncovalent modification of chromatin: different remodeled products with different ATPase domains. Cold Spring Harb Symp Quant Biol. 2004; 69:183-92. Fan HY, Narlikar GJ, Kingston RE. PMID: 16117648.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    84. Distinct strategies to make nucleosomal DNA accessible. Mol Cell. 2003 May; 11(5):1311-22. Fan HY, He X, Kingston RE, Narlikar GJ. PMID: 12769854.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    85. Nucleosome remodeling by the human SWI/SNF complex requires transient global disruption of histone-DNA interactions. Mol Cell Biol. 2002 Jun; 22(11):3653-62. Aoyagi S, Narlikar G, Zheng C, Sif S, Kingston RE, Hayes JJ. PMID: 11997502; PMCID: PMC133810.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    86. Cooperation between complexes that regulate chromatin structure and transcription. Cell. 2002 Feb 22; 108(4):475-87. Narlikar GJ, Fan HY, Kingston RE. PMID: 11909519.
      View in: PubMed   Mentions: 551     Fields:    Translation:HumansAnimalsCells
    87. Generation and interconversion of multiple distinct nucleosomal states as a mechanism for catalyzing chromatin fluidity. Mol Cell. 2001 Dec; 8(6):1219-30. Narlikar GJ, Phelan ML, Kingston RE. PMID: 11779498.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    88. Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H. J Biol Chem. 2001 Sep 07; 276(36):34270-8. Aalfs JD, Narlikar GJ, Kingston RE. PMID: 11435432.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    89. Assembly of nucleosomal templates by salt dialysis. Curr Protoc Mol Biol. 2001 May; Chapter 21:Unit 21.6. Lee KM, Narlikar G. PMID: 18265198.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    90. Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem. 2001 May 11; 276(19):16279-88. Jónsson ZO, Dhar SK, Narlikar GJ, Auty R, Wagle N, Pellman D, Pratt RE, Kingston R, Dutta A. PMID: 11278922.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    91. Stability of a human SWI-SNF remodeled nucleosomal array. Mol Cell Biol. 2001 Feb; 21(4):1132-44. Guyon JR, Narlikar GJ, Sullivan EK, Kingston RE. PMID: 11158300; PMCID: PMC99567.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    92. Use of duplex rigidity for stability and specificity in RNA tertiary structure. Biochemistry. 2000 May 23; 39(20):6183-9. Narlikar GJ, Bartley LE, Herschlag D. PMID: 10821693.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    93. Characterization of a local folding event of the Tetrahymena group I ribozyme: effects of oligonucleotide substrate length, pH, and temperature on the two substrate binding steps. Biochemistry. 1999 Oct 26; 38(43):14192-204. Narlikar GJ, Bartley LE, Khosla M, Herschlag D. PMID: 10571993.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    94. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity. Genes Dev. 1999 Sep 15; 13(18):2339-52. Kingston RE, Narlikar GJ. PMID: 10500090.
      View in: PubMed   Mentions: 210     Fields:    Translation:HumansAnimalsCells
    95. Protonated 2'-aminoguanosine as a probe of the electrostatic environment of the active site of the Tetrahymena group I ribozyme. Biochemistry. 1999 Aug 24; 38(34):10976-88. Shan SO, Narlikar GJ, Herschlag D. PMID: 10460152.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    96. Stable remodeling of tailless nucleosomes by the human SWI-SNF complex. Mol Cell Biol. 1999 Mar; 19(3):2088-97. Guyon JR, Narlikar GJ, Sif S, Kingston RE. PMID: 10022896; PMCID: PMC84002.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    97. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Mol Cell. 1999 Feb; 3(2):247-53. Phelan ML, Sif S, Narlikar GJ, Kingston RE. PMID: 10078207.
      View in: PubMed   Mentions: 280     Fields:    Translation:HumansCells
    98. Direct demonstration of the catalytic role of binding interactions in an enzymatic reaction. Biochemistry. 1998 Jul 14; 37(28):9902-11. Narlikar GJ, Herschlag D. PMID: 9665695.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    99. Quantitating tertiary binding energies of 2' OH groups on the P1 duplex of the Tetrahymena ribozyme: intrinsic binding energy in an RNA enzyme. Biochemistry. 1997 Mar 04; 36(9):2465-77. Narlikar GJ, Khosla M, Usman N, Herschlag D. PMID: 9054551.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    100. Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes. Annu Rev Biochem. 1997; 66:19-59. Narlikar GJ, Herschlag D. PMID: 9242901.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    101. Isolation of a local tertiary folding transition in the context of a globally folded RNA. Nat Struct Biol. 1996 Aug; 3(8):701-10. Narlikar GJ, Herschlag D. PMID: 8756329.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    102. Use of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization. Proc Natl Acad Sci U S A. 1995 Apr 25; 92(9):3668-72. Narlikar GJ, Gopalakrishnan V, McConnell TS, Usman N, Herschlag D. PMID: 7731962; PMCID: PMC42022.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    103. Dissection of the role of the conserved G.U pair in group I RNA self-splicing. Biochemistry. 1994 Nov 22; 33(46):13864-79. Knitt DS, Narlikar GJ, Herschlag D. PMID: 7947795.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
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