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Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A. ACS Chem Biol. 2021 Feb 23.
Longbotham JE, Kelly MJS, Fujimori DG. PMID: 33621062.
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1 Fields:
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Expanding the space of protein geometries by computational design of de novo fold families. Science. 2020 08 28; 369(6507):1132-1136.
Pan X, Thompson MC, Zhang Y, Liu L, Fraser JS, Kelly MJS, Kortemme T. PMID: 32855341.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Computational design of a modular protein sense-response system. Science. 2019 11 22; 366(6468):1024-1028.
Glasgow AA, Huang YM, Mandell DJ, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T. PMID: 31754004.
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PubMed Mentions:
7 Fields:
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Cells
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Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis. Nat Commun. 2019 09 17; 10(1):4223.
Kant S, Craige SM, Chen K, Reif MM, Learnard H, Kelly M, Caliz AD, Tran KV, Ramo K, Peters OM, Freeman M, Davis RJ, Keaney JF. PMID: 31530804.
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PubMed Mentions:
4 Fields:
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HumansAnimalsCells
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A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain. Cell. 2019 09 05; 178(6):1362-1374.e16.
Lin King JV, Emrick JJ, Kelly MJS, Herzig V, King GF, Medzihradszky KF, Julius D. PMID: 31447178.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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HDAC inhibition in glioblastoma monitored by hyperpolarized 13 C MRSI. NMR Biomed. 2019 02; 32(2):e4044.
Radoul M, Najac C, Viswanath P, Mukherjee J, Kelly M, Gillespie AM, Chaumeil MM, Eriksson P, Delos Santos R, Pieper RO, Ronen SM. PMID: 30561869.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles. PLoS One. 2018; 13(1):e0190530.
Citron YR, Fagerstrom CJ, Keszthelyi B, Huang B, Rusan NM, Kelly MJS, Agard DA. PMID: 29315319.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nat Chem. 2017 09; 9(9):874-881.
Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. PMID: 28837163.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. ACS Med Chem Lett. 2016 Feb 11; 7(2):182-7.
Alverez C, Bulfer SL, Chakrasali R, Chimenti MS, Deshaies RJ, Green N, Kelly M, LaPorte MG, Lewis TS, Liang M, Moore WJ, Neitz RJ, Peshkov VA, Walters MA, Zhang F, Arkin MR, Wipf P, Huryn DM. PMID: 26985295.
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Allosteric N-WASP activation by an inter-SH3 domain linker in Nck. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):E6436-45.
Okrut J, Prakash S, Wu Q, Kelly MJ, Taunton J. PMID: 26554011.
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PubMed Mentions:
11 Fields:
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HumansAnimalsCells
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Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism. Nat Commun. 2015 Feb 17; 6:6204.
Torres IO, Kuchenbecker KM, Nnadi CI, Fletterick RJ, Kelly MJ, Fujimori DG. PMID: 25686748.
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PubMed Mentions:
39 Fields:
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HumansAnimalsCells
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A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. J Biomol Screen. 2015 Jul; 20(6):788-800.
Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James TL, Arkin MR, Kelly MJ. PMID: 25690569.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Biophysical methods for identifying fragment-based inhibitors of protein-protein interactions. Methods Mol Biol. 2015; 1278:587-613.
Pfaff SJ, Chimenti MS, Kelly MJ, Arkin MR. PMID: 25859978.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone. J Mol Biol. 2014 Jun 12; 426(12):2393-404.
Street TO, Zeng X, Pellarin R, Bonomi M, Sali A, Kelly MJ, Chu F, Agard DA. PMID: 24726919.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation. Anesthesiology. 2013 Nov; 119(5):1120-36.
Liu J, Segal MR, Kelly MJ, Pelton JG, Kim M, James TL, Litt L. PMID: 23748856.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries. Pediatr Res. 2013 Aug; 74(2):170-9.
Liu J, Sheldon RA, Segal MR, Kelly MJ, Pelton JG, Ferriero DM, James TL, Litt L. PMID: 23708689.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Design of a phosphorylatable PDZ domain with peptide-specific affinity changes. Structure. 2013 Jan 08; 21(1):54-64.
Smith CA, Shi CA, Chroust MK, Bliska TE, Kelly MJS, Jacobson MP, Kortemme T. PMID: 23159126.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. Int J Mol Sci. 2011; 12(10):6469-501.
Liu J, Litt L, Segal MR, Kelly MJ, Pelton JG, Kim M. PMID: 22072900.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion. J Mol Biol. 2011 Apr 22; 408(1):1-8.
Foo CK, Ohhashi Y, Kelly MJ, Tanaka M, Weissman JS. PMID: 21333653.
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PubMed Mentions:
7 Fields:
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AnimalsCells
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Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab. 2011 Feb; 31(2):547-59.
Liu J, Litt L, Segal MR, Kelly MJ, Yoshihara HA, James TL. PMID: 20717124.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding. J Cell Biol. 2008 Dec 01; 183(5):865-79.
Frantz C, Barreiro G, Dominguez L, Chen X, Eddy R, Condeelis J, Kelly MJ, Jacobson MP, Barber DL. PMID: 19029335.
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PubMed Mentions:
84 Fields:
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HumansAnimalsCells
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Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices. Anesthesiology. 2007 Oct; 107(4):630-40.
Zeng J, Liu J, Yang GY, Kelly MJ, James TL, Litt L. PMID: 17893460.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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The structural basis of yeast prion strain variants. Nature. 2007 Sep 13; 449(7159):233-7.
Toyama BH, Kelly MJ, Gross JD, Weissman JS. PMID: 17767153.
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PubMed Mentions:
174 Fields:
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AnimalsCells
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Parallel beta-helix proteins required for accurate capsule polysaccharide synthesis and virulence in the yeast Cryptococcus neoformans. Eukaryot Cell. 2007 Apr; 6(4):630-40.
Liu OW, Kelly MJ, Chow ED, Madhani HD. PMID: 17337638.
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PubMed Mentions:
12 Fields:
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AnimalsCells
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Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab. 2007 Feb; 27(2):304-15.
Zeng J, Yang GY, Ying W, Kelly M, Hirai K, James TL, Swanson RA, Litt L. PMID: 16736046.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices. J Bioenerg Biomembr. 2004 Aug; 36(4):415-9.
Zeng J, Hirai K, Yang GY, Ying W, Swanson RA, Kelly M, Mayer M, James TL, Litt L. PMID: 15377881.
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PubMed Mentions:
2 Fields:
Translation:
Animals