John Hixson, MD

Title(s)Professor, Neurology
SchoolSchool of Medicine
Phone415-221-4810 ext. 4797
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Collapse Education and Training
    Texas A&M UniversityBS1997Biochemistry and Genetics
    Johns Hopkins School of MedicineMD2001Medicine
    Hospital of the University of PennsylvaniaResidency2005Neurology
    University of Iowa Hospitals and ClinicsFellowship2006Epilepsy and Clinical Neurophysiology

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    I'm currently a faculty member in the Dept of Neurology at both UCSF and the SF VA Medical Center. I primarily treat epilepsy patients, but am also developing several projects exploring the use of mobile health applications to improve the longitudinal care of patients with chronic disease. More specifically, I am interested in conducting clinical trials utilizing mobile health technologies (online diary systems and databases, electronic pillboxes) to improve clinical outcomes and cost efficiency. I am a part of the UCSF mHealth Group and the VA Innovations Initiative Patient-Facing Effort.

    I am always eager to discuss these mobile health interests (mhealth) more specifically and am looking for collaborators!


    From the UCSF Epilepsy Website:

    Dr. John D. Hixson is a neurologist specializing in the evaluation and treatment of epilepsy and seizures. His research interests include emotion processing in temporal lobe epilepsy, antiepileptic drug management, and psychogenic nonepileptic seizures (PNES). Dr. Hixson also spends part of his time working on public advocacy and health service issues as relates to epilepsy care.

    Dr. Hixson is an assistant professor of clinical neurology at UCSF. He earned a medical degree at Johns Hopkins University School of Medicine and completed a residency in neurology at the Hospital of the University of Pennsylvania in Philadelphia. Following residency, he conducted research and completed a fellowship in epilepsy and neurophysiology at the University of Iowa Hospitals and Clinics. Dr. Hixson serves on the policy advisory board of the Epilepsy Foundation of Northern California and on the advocacy advisory board of the American Academy of Neurology. He also serves as the medical editor-in-chief for the AAN News publication.

    Specialities: Epilepsy, Neurology

    Education: Johns Hopkins University School of Medicine, 2001

    Residencies: Hospital of the University of Pennsylvania - Neurology, 2005

    Fellowship: University of Iowa Hospitals and Clinics, 2006

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Video quality using outpatient smartphone videos in epilepsy: Results from the OSmartViE study. Eur J Neurol. 2021 05; 28(5):1453-1462. Tatum WO, Hirsch LJ, Gelfand MA, Acton EK, LaFrance WC, Duckrow RB, Chen D, Blum AS, Hixson J, Drazkowski J, Benbadis S, Cascino GD, OSmartViE Collaborators . PMID: 33465822.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Efficacy and safety of eslicarbazepine acetate as a first or later adjunctive therapy in patients with focal seizures. Epilepsy Res. 2021 Mar; 171:106561. Hixson J, Gidal B, Pikalov A, Zhang Y, Mehta D, Blum D, Cantu D, Grinnell T, Study 701 Investigators . PMID: 33556737.
      View in: PubMed   Mentions:    Fields:    
    3. Focal nonmotor versus motor seizures: The impact on diagnostic delay in focal epilepsy. Epilepsia. 2020 12; 61(12):2643-2652. Pellinen J, Tafuro E, Yang A, Price D, Friedman D, Holmes M, Barnard S, Detyniecki K, Hegde M, Hixson J, Haut S, Kälviäinen R, French J, Human Epilepsy Project Co-Investigators . PMID: 33078409.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Neuro-Oncology Practice Clinical Debate: long-term antiepileptic drug prophylaxis in patients with glioma. Neurooncol Pract. 2020 Dec; 7(6):583-588. Stocksdale B, Nagpal S, Hixson JD, Johnson DR, Rai P, Shivaprasad A, Tremont-Lukats IW. PMID: 33312673.
      View in: PubMed   Mentions:
    5. Assessment of the Predictive Value of Outpatient Smartphone Videos for Diagnosis of Epileptic Seizures. JAMA Neurol. 2020 05 01; 77(5):593-600. Tatum WO, Hirsch LJ, Gelfand MA, Acton EK, LaFrance WC, Duckrow RB, Chen DK, Blum AS, Hixson JD, Drazkowski JF, Benbadis SR, Cascino GD, OSmartViE Investigators . PMID: 31961382.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    6. Digital and technological opportunities in epilepsy: Toward a digital ecosystem for enhanced epilepsy management. Epilepsy Behav. 2020 01; 102:106663. Shegog R, Braverman L, Hixson JD. PMID: 31778878.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Digital tools for epilepsy: Opportunities and barriers. Epilepsy Res. 2020 05; 162:106233. Hixson JD, Braverman L. PMID: 32199221.
      View in: PubMed   Mentions:    Fields:    
    8. Self-Management in Epilepsy Care: Untapped Opportunities. Fed Pract. 2018 Apr; 35(Suppl 3):S10-S16. Ozuna J, Kelly P, Towne A, Hixson J. PMID: 30766395.
      View in: PubMed   Mentions:
    9. Common data elements for epilepsy mobile health systems. Epilepsia. 2018 05; 59(5):1020-1026. Goldenholz DM, Moss R, Jost DA, Crone NE, Krauss G, Picard R, Caborni C, Cavazos JE, Hixson J, Loddenkemper T, Salazar TD, Lubbers L, Harte-Hargrove LC, Whittemore V, Duun-Henriksen J, Dolan E, Kasturia N, Oberemk M, Cook MJ, Lehmkuhle M, Sperling MR, Shafer PO. PMID: 29604050.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Is seizure frequency variance a predictable quantity? Ann Clin Transl Neurol. 2018 02; 5(2):201-207. Goldenholz DM, Goldenholz SR, Moss R, French J, Lowenstein D, Kuzniecky R, Haut S, Cristofaro S, Detyniecki K, Hixson J, Karoly P, Cook M, Strashny A, Theodore WH. PMID: 29468180.
      View in: PubMed   Mentions: 6     Fields:    
    11. Does accounting for seizure frequency variability increase clinical trial power? Epilepsy Res. 2017 11; 137:145-151. Goldenholz DM, Goldenholz SR, Moss R, French J, Lowenstein D, Kuzniecky R, Haut S, Cristofaro S, Detyniecki K, Hixson J, Karoly P, Cook M, Strashny A, Theodore WH, Pieper C. PMID: 28781216.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia. Brain. 2016 12; 139(Pt 12):3202-3216. Vatsavayai SC, Yoon SJ, Gardner RC, Gendron TF, Vargas JN, Trujillo A, Pribadi M, Phillips JJ, Gaus SE, Hixson JD, Garcia PA, Rabinovici GD, Coppola G, Geschwind DH, Petrucelli L, Miller BL, Seeley WW. PMID: 27797809.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    13. Mobile health: the power of wearables, sensors, and apps to transform clinical trials. Ann N Y Acad Sci. 2016 07; 1375(1):3-18. Munos B, Baker PC, Bot BM, Crouthamel M, de Vries G, Ferguson I, Hixson JD, Malek LA, Mastrototaro JJ, Misra V, Ozcan A, Sacks L, Wang P. PMID: 27384501.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    14. Patients optimizing epilepsy management via an online community: the POEM Study. Neurology. 2015 Jul 14; 85(2):129-36. Hixson JD, Barnes D, Parko K, Durgin T, Van Bebber S, Graham A, Wicks P. PMID: 26085605.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    15. Interest in a digital health tool in veterans with epilepsy: results of a phone survey. Mil Med. 2015 Apr; 180(4):387-90. Hixson JD, Van Bebber SL, Bertko KM. PMID: 25826343.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Seizure diaries for clinical research and practice: limitations and future prospects. Epilepsy Behav. 2012 Jul; 24(3):304-10. Fisher RS, Blum DE, DiVentura B, Vannest J, Hixson JD, Moss R, Herman ST, Fureman BE, French JA. PMID: 22652423.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    17. When physicians disagree: a case of nonconvulsive status epilepticus. Continuum (Minneap Minn). 2011 Oct; 17(5 Neurologic Consultation in the Hospital):1119-23. Hixson JD. PMID: 22809985.
      View in: PubMed   Mentions:    Fields:    
    18. Stopping antiepileptic drugs: when and why? Curr Treat Options Neurol. 2010 Sep; 12(5):434-42. Hixson JD. PMID: 20730110.
      View in: PubMed   Mentions:
    19. The effects of epilepsy and its treatments on affect and emotion. Neurocase. 2009 Jun; 15(3):206-16. Hixson JD, Kirsch HE. PMID: 19204849.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Fear sensitivity and the psychological profile of patients with psychogenic nonepileptic seizures. Epilepsy Behav. 2006 Dec; 9(4):587-92. Hixson JD, Balcer LJ, Glosser G, French JA. PMID: 16997635.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Guidelines for new antiepileptic drug evaluation. Rev Neurol Dis. 2004; 1 Suppl 1:S18-26. Hixson JD, French JA. PMID: 16400291.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    22. The distal elements, OCT and SPH, stimulate the formation of preinitiation complexes on a human U6 snRNA gene promoter in vitro. Nucleic Acids Res. 1998 Mar 15; 26(6):1536-43. Kunkel GR, Hixson JD. PMID: 9490803.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Intrinsic fluorescence studies of the chaperonin GroEL containing single Tyr --> Trp replacements reveal ligand-induced conformational changes. J Biol Chem. 1996 Dec 13; 271(50):31989-95. Gibbons DL, Hixson JD, Hay N, Lund P, Gorovits BM, Ybarra J, Horowitz PM. PMID: 8943246.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
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