Heidi Kirsch, MD, MS

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address513 Parnassus Ave, MSB, #672E
San Francisco CA 94117
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences

    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityA.B.1991Biological Anthropology
    University of California, BerkeleyM.S.1994School of Public Health (Joint Medical Program)
    University of California, San FranciscoM.D.1996 Medicine
    GeorgetownResidency (PGY-1)1997Medicine/Transitional Year
    Johns HopkinsResidency, Chief residency2000Neurology
    Johns HopkinsFellowship2002Epilepsy and Clinical Neurophysiology
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    Dr. Heidi Kirsch is a specialist in epilepsy treatment (epileptology) and is board certified in epilepsy, neurology and clinical neurophysiology. She joined UCSF Medical Center in 2002 and is a Professor of Clinical Neurology and Radiology and Biomedical Imaging. She is the Clinical Director of the UCSF Biomagnetic Imaging Laboratory (UCSF's MEG lab), where she works mapping epileptic activity and functional areas in the brain to plan epilepsy and other types of brain surgery. In her research, she studies new methods of brain mapping and the ways in which seizures spread in the brain. She also directs the Foundational Science in F2 in the UCSF School of Medicine Bridges Curriculum, where students integrate basic science principles into clinical reasoning.

    Kirsch earned an undergraduate degree magna cum laude at Harvard and a master's degree in Health and Medical Sciences and a medical degree from the Joint Medical Program offered by the University of California at Berkeley and UCSF. She completed an internship at Georgetown University and a neurology residency at Johns Hopkins Hospital, where she was a fellow in clinical neurophysiology and epilepsy. During her fellowship, she was a volunteer to the Cognitive Neuroscience Section of the National Institutes of Health (NIH). She is a member of the board of directors of the American Clinical Magentoencephalography Society and past president of the board of directors of the Epilepsy Foundation of Northern California, and a member of the American Neurological Association, the American Academy of Neurology and the American Epilepsy Society. She serves as an ad hoc reviewer for several journals, including the Annals of Neurology and Neurology.

    Collapse Research 
    Collapse Research Activities and Funding
    The Effect of Epilepsy Surgery on Social Cognition
    NIH K23NS047100May 1, 2004 - Apr 30, 2010
    Role: Principal Investigator

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    Collapse Featured Publications
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Abnormal gamma phase-amplitude coupling in the parahippocampal cortex is associated with network hyperexcitability in Alzheimer’s disease. Brain Communications. 2024 Apr 9; fcae121. Prabhu PP, Morise MH, Kudo KK, Beagle BA, Mizuiri MD, Syed SF, Kotegar KK, Findlay FA, Miller MB, Kramer KJ, Rankin RK, Garcia GP, Kirsch KH, Vossel VK, Nagarajan NS, Ranasinghe RK. .
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    2. Neurophysiological trajectories in Alzheimer's disease progression. Elife. 2024 Mar 28; 12. Kudo K, Ranasinghe KG, Morise H, Syed F, Sekihara K, Rankin KP, Miller BL, Kramer JH, Rabinovici GD, Vossel K, Kirsch HE, Nagarajan SS. PMID: 38546337; PMCID: PMC10977971.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Neurophysiological trajectories in Alzheimer’s disease progression. eLife. 2024 Mar 28; 12. Kudo KK, Ranasinghe RK, Morise MH, Syed SF, Sekihara SK, Rankin RK, Miller MB, Kramer KJ, Rabinovici RG, Vossel VK, Kirsch KH, Nagarajan NS. .
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    4. Neurophysiological trajectories in Alzheimer's disease progression. bioRxiv. 2024 Mar 08. Kudo K, Ranasinghe KG, Morise H, Syed F, Sekihara K, Rankin KP, Miller BL, Kramer JH, Rabinovici GD, Vossel K, Kirsch HE, Nagarajan SS. PMID: 37293044; PMCID: PMC10245777.
      View in: PubMed   Mentions:
    5. Spatiotemporal characteristics of neurophysiological changes in patients with four-repeat tauopathies. Ann Clin Transl Neurol. 2024 02; 11(2):525-535. Samudra N, Lerner H, Yack L, Walsh CM, Kirsch HE, Kudo K, Yballa C, La Joie R, Gorno-Tempini ML, Spina S, Seeley WW, Neylan TC, Miller BL, Rabinovici GD, Boxer A, Grinberg LT, Rankin KP, Nagarajan SS, Ranasinghe KG. PMID: 38226843; PMCID: PMC10863921.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Cortical Synchrony and Information Flow during Transition from Wakefulness to Light Non-Rapid Eye Movement Sleep. J Neurosci. 2023 11 29; 43(48):8157-8171. Fan JM, Kudo K, Verma P, Ranasinghe KG, Morise H, Findlay AM, Vossel K, Kirsch HE, Raj A, Krystal AD, Nagarajan SS. PMID: 37788939; PMCID: PMC10697405.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Abnormal gamma frequency phase-amplitude coupling associated with network hyperexcitability in Alzheimer’s Disease. Alzheimer's & Dementia. 2023 Jun 16; 19(S3). Prabhu PP, Ranasinghe RK, Morise MH, Kudo KK, Hinkley HL, Lerner LH, Mizuiri MD, Licata LA, Kotegar KK, Findlay FA, Miller MB, Gorno-Tempini GM, Kramer KJ, Rankin RK, Garcia GP, Kirsch KH, Houde HJ, Vossel VK, Nagarajan NS. .
      View in: Publisher Site   Mentions:
    8. Functional Investigation of Somatic Variants in Pediatric Epilepsy Using Single-Cell DNA/RNA Assays from Patient Derived Single Cells (P3-9.009). Neurology. 2023 Apr 25; 100(17_supplement_2). Cheng CD, Chen CM, Huang HA, Park PJ, Kirsch KH, Walsh WC, Shao SD. .
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    9. Etiology and Clinical Significance of Network Hyperexcitability in Alzheimer's Disease: Unanswered Questions and Next Steps. J Alzheimers Dis. 2023; 92(1):13-27. Samudra N, Ranasinghe K, Kirsch H, Rankin K, Miller B. PMID: 36710680.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Maintaining Medical Student Motivation During Remote Clinical Learning. Acad Med. 2023 01 01; 98(1):105-111. Charondo LB, Duque JB, Kirsch HE, Brondfield S. PMID: 36044278.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. What Is Different about Teratoma-Associated Anti-LGI1 Encephalitis? A Long-Term Clinical and Neuroimaging Case Series. Eur Neurol. 2022; 85(6):437-445. Li C, Cai HB, Zhao X, Xi XC, Zhou Q, Luo HY, Tang ZP, Kang HC, Kirsch HE. PMID: 35896086.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Applying cognitive integration to oncology: A novel asynchronous foundational science curriculum for medical students during clerkships. Journal of Clinical Oncology. 2022 Jun 1; 40(16_suppl):11028-11028. Brondfield BS, Hyland HK, Cornett CP, Kirsch KH. .
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    13. Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy. Brain Commun. 2022; 4(3):fcac104. Fan JM, Lee AT, Kudo K, Ranasinghe KG, Morise H, Findlay AM, Kirsch HE, Chang EF, Nagarajan SS, Rao VR. PMID: 35611310; PMCID: PMC9123848.
      View in: PubMed   Mentions: 7  
    14. Neuronal synchrony abnormalities associated with subclinical epileptiform activity in early-onset Alzheimer's disease. Brain. 2022 04 18; 145(2):744-753. Ranasinghe KG, Kudo K, Hinkley L, Beagle A, Lerner H, Mizuiri D, Findlay A, Miller BL, Kramer JH, Gorno-Tempini ML, Rabinovici GD, Rankin KP, Garcia PA, Kirsch HE, Vossel K, Nagarajan SS. PMID: 34919638; PMCID: PMC9630715.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    15. "What is the mechanism?": Cues, barriers, and opportunities to discuss foundational science during internal medicine rounds. Med Teach. 2022 07; 44(7):765-771. Pai JS, Kirsch HE, O'Sullivan PS, Cornett PA. PMID: 35132917.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Spike-Associated Networks Predict Postsurgical Outcomes in Children With Refractory Epilepsy. J Clin Neurophysiol. 2023 Feb 01; 40(2):123-129. Bear JJ, Sargent JL, O'Neill BR, Chapman KE, Ghosh D, Kirsch HE, Tregellas JR. PMID: 34817446; PMCID: PMC9124720.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial. JAMA Neurol. 2021 11 01; 78(11):1345-1354. Vossel K, Ranasinghe KG, Beagle AJ, La A, Ah Pook K, Castro M, Mizuiri D, Honma SM, Venkateswaran N, Koestler M, Zhang W, Mucke L, Howell MJ, Possin KL, Kramer JH, Boxer AL, Miller BL, Nagarajan SS, Kirsch HE. PMID: 34570177; PMCID: PMC8477304.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCTClinical Trials
    18. Investigation of the risk of valproic acid-induced tremor: clinical, neuroimaging, and genetic factors. Psychopharmacology (Berl). 2022 Jan; 239(1):173-184. Lan L, Zhao X, Jian S, Li C, Wang M, Zhou Q, Huang S, Zhu S, Kang H, Kirsch HE. PMID: 34718848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Long QT syndrome with potassium voltage-gated channel subfamily H member 2 gene mutation mimicking refractory epilepsy: case report. BMC Neurol. 2021 Sep 04; 21(1):338. Kang H, Lan L, Jia Y, Li C, Fang Y, Zhu S, Kirsch H. PMID: 34481479; PMCID: PMC8418736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Magnetoencephalography Imaging Reveals Abnormal Information Flow in Temporal Lobe Epilepsy. Brain Connect. 2022 05; 12(4):362-373. Kudo K, Morise H, Ranasinghe KG, Mizuiri D, Bhutada AS, Chen J, Findlay A, Kirsch HE, Nagarajan SS. PMID: 34210170; PMCID: PMC9131359.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Integrated in silico and experimental assessment of disease relevance of PCDH19 missense variants. Hum Mutat. 2021 08; 42(8):1030-1041. Pham DH, Pitman MR, Kumar R, Jolly LA, Schulz R, Gardner AE, de Nys R, Heron SE, Corbett MA, Kothur K, Gill D, Rajagopalan S, Kolc KL, Halliday BJ, Robertson SP, Regan BM, Kirsch HE, Berkovic SF, Scheffer IE, Pitson SM, Petrovski S, Gecz J. PMID: 34082468.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Clinical Validation of the Champagne Algorithm for Evoked Response Source Localization in Magnetoencephalography. Brain Topogr. 2022 01; 35(1):96-107. Bhutada AS, Cai C, Mizuiri D, Findlay A, Chen J, Tay A, Kirsch HE, Nagarajan SS. PMID: 34114168; PMCID: PMC8664897.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Clinical Validation of the Champagne Algorithm for Epilepsy Spike Localization. Front Hum Neurosci. 2021; 15:642819. Cai C, Chen J, Findlay AM, Mizuiri D, Sekihara K, Kirsch HE, Nagarajan SS. PMID: 34093150; PMCID: PMC8172809.
      View in: PubMed   Mentions: 2  
    24. 073 Whole-brain network analysis of neural oscillations during light sleep. Sleep. 2021 May 3; 44(Supplement_2):a30-a31. Fan FJ, Kudo KK, Ranasinghe RK, Morise MH, Findlay FA, Kirsch KH, Krystal KA, Nagarajan NS. .
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    25. The 10 Common Evidence-Supported Indications for MEG in Epilepsy Surgery: An Illustrated Compendium. J Clin Neurophysiol. 2020 Nov; 37(6):483-497. Bagic AI, Funke ME, Kirsch HE, Tenney JR, Zillgitt AJ, Burgess RC. PMID: 33165222.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. The effects of epilepsy and its treatments on affect and emotion. . 2020 Oct 8; 206-216. Hixson HJ, Kirsch KH. .
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    27. Familial aggregation of status epilepticus in generalized and focal epilepsies. Neurology. 2020 10 13; 95(15):e2140-e2149. Weisenberg JLZ, Fitzgerald RT, Constantino JN, Winawer MR, Thio LL, EPGP Investigators. PMID: 32917807; PMCID: PMC7713751.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Semantic Similarity Analysis Reveals Robust Gene-Disease Relationships in Developmental and Epileptic Encephalopathies. Am J Hum Genet. 2020 10 01; 107(4):683-697. Galer PD, Ganesan S, Lewis-Smith D, McKeown SE, Pendziwiat M, Helbig KL, Ellis CA, Rademacher A, Smith L, Poduri A, Seiffert S, von Spiczak S, Muhle H, van Baalen A, NCEE Study Group, EPGP Investigators, EuroEPINOMICS-RES Consortium, Genomics Research and Innovation Network, Thomas RH, Krause R, Weber Y, Helbig I. PMID: 32853554; PMCID: PMC7536581.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    29. Spike-associated networks and intracranial electrographic findings. Epileptic Disord. 2020 Jun 01; 22(3):291-299. Bear JJ, Kirsch HE, Berman BD, Chapman KE, Tregellas JR. PMID: 32554357.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Optimizing Magnetoencephalographic Imaging Estimation of Language Lateralization for Simpler Language Tasks. Front Hum Neurosci. 2020; 14:105. Hinkley LBN, De Witte E, Cahill-Thompson M, Mizuiri D, Garrett C, Honma S, Findlay A, Gorno-Tempini ML, Tarapore P, Kirsch HE, Mariën P, Houde JF, Berger M, Nagarajan SS. PMID: 32499685; PMCID: PMC7242765.
      View in: PubMed   Mentions: 5  
    31. Direct Evidence for Prediction Signals in Frontal Cortex Independent of Prediction Error. Cereb Cortex. 2019 12 17; 29(11):4530-4538. Dürschmid S, Reichert C, Hinrichs H, Heinze HJ, Kirsch HE, Knight RT, Deouell LY. PMID: 30590422; PMCID: PMC7963121.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    32. Comparison of DSSP and tSSS algorithms for removing artifacts from vagus nerve stimulators in magnetoencephalography data. J Neural Eng. 2019 11 12; 16(6):066045. Cai C, Kang H, Kirsch HE, Mizuiri D, Chen J, Bhutada A, Sekihara K, Nagarajan SS. PMID: 31476752.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. Emotion recognition in objects in patients with neurological disease. Neuropsychology. 2019 Nov; 33(8):1163-1173. Shiota MN, Simpson ML, Kirsch HE, Levenson RW. PMID: 31478721; PMCID: PMC6823118.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Evaluation of a dual signal subspace projection algorithm in magnetoencephalographic recordings from patients with intractable epilepsy and vagus nerve stimulators. Neuroimage. 2019 03; 188:161-170. Cai C, Xu J, Velmurugan J, Knowlton R, Sekihara K, Nagarajan SS, Kirsch H. PMID: 30502448.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. Differential Sources for 2 Neural Signatures of Target Detection: An Electrocorticography Study. Cereb Cortex. 2018 01 01; 28(1):9-20. Kam JWY, Szczepanski SM, Canolty RT, Flinker A, Auguste KI, Crone NE, Kirsch HE, Kuperman RA, Lin JJ, Parvizi J, Knight RT. PMID: 29253249; PMCID: PMC6454481.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    36. The nociferous influence of interictal discharges on memory. Brain. 2017 08 01; 140(8):2072-2074. Kleen JK, Kirsch HE. PMID: 28899025; PMCID: PMC6248646.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    37. DNM1 encephalopathy: A new disease of vesicle fission. Neurology. 2017 Jul 25; 89(4):385-394. von Spiczak S, Helbig KL, Shinde DN, Huether R, Pendziwiat M, Lourenço C, Nunes ME, Sarco DP, Kaplan RA, Dlugos DJ, Kirsch H, Slavotinek A, Cilio MR, Cervenka MC, Cohen JS, McClellan R, Fatemi A, Yuen A, Sagawa Y, Littlejohn R, McLean SD, Hernandez-Hernandez L, Maher B, Møller RS, Palmer E, Lawson JA, Campbell CA, Joshi CN, Kolbe DL, Hollingsworth G, Neubauer BA, Muhle H, Stephani U, Scheffer IE, Pena SDJ, Sisodiya SM, Helbig I, Epi4K Consortium, EuroEPINOMICS-RES NLES Working Group. PMID: 28667181; PMCID: PMC5574673.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    38. Familial aggregation of focal seizure semiology in the Epilepsy Phenome/Genome Project. Neurology. 2017 Jul 04; 89(1):22-28. Tobochnik S, Fahlstrom R, Shain C, Winawer MR, EPGP Investigators. PMID: 28566546; PMCID: PMC5496514.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    39. American Clinical MEG Society (ACMEGS) Position Statement #2: The Value of Magnetoencephalography (MEG)/Magnetic Source Imaging (MSI) in Noninvasive Presurgical Mapping of Eloquent Cortices of Patients Preparing for Surgical Interventions. J Clin Neurophysiol. 2017 May; 34(3):189-195. Bagic AI, Bowyer SM, Kirsch HE, Funke ME, Burgess RC, ACMEGS Position Statement Committee. PMID: 28059855.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    40. Incidence and impact of subclinical epileptiform activity in Alzheimer's disease. Ann Neurol. 2016 12; 80(6):858-870. Vossel KA, Ranasinghe KG, Beagle AJ, Mizuiri D, Honma SM, Dowling AF, Darwish SM, Van Berlo V, Barnes DE, Mantle M, Karydas AM, Coppola G, Roberson ED, Miller BL, Garcia PA, Kirsch HE, Mucke L, Nagarajan SS. PMID: 27696483; PMCID: PMC5177487.
      View in: PubMed   Mentions: 187     Fields:    Translation:Humans
    41. Concordance between interictal MEG and stereo-EEG predicts seizure freedom after epilepsy surgery. Brain. 2016 11 01; 139(11):2821-2823. Bear J, Kirsch H. PMID: 29106488.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. NIMG-27. LANGUAGE LATERALIZATION ASSESSED BY MAGNETOENCEPHALOGRAPHY IMAGING USING THREE DIFFERENT LANGUAGE TASKS. Neuro-Oncology. 2016 Nov 1; 18(suppl_6):vi130-vi130. Witte WE, Hinkley HL, Mizuiri MD, Garrett GC, Honma HS, Kirsch KH, Houde HJ, Berger BM, Nagarajan NS. .
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    43. 206 Spikes, Slowing, and Functional Connectivity. Neurosurgery. 2016 Aug 1; 63:181. Englot ED, Rolston RJ, Wang WD, Kirsch KH, Nagarajan NS, Chang CE. .
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    44. Ictal fear: Associations with age, gender, and other experiential phenomena. Epilepsy Behav. 2016 09; 62:153-8. Chong DJ, Dugan P, EPGP Investigators. PMID: 27479777.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    45. Hierarchy of prediction errors for auditory events in human temporal and frontal cortex. Proc Natl Acad Sci U S A. 2016 06 14; 113(24):6755-60. Dürschmid S, Edwards E, Reichert C, Dewar C, Hinrichs H, Heinze HJ, Kirsch HE, Dalal SS, Deouell LY, Knight RT. PMID: 27247381; PMCID: PMC4914143.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    46. Genetic effects on sleep/wake variation of seizures. Epilepsia. 2016 Apr; 57(4):557-65. Winawer MR, Shih J, Beck ES, Hunter JE, Epstein MP, EPGP Investigators. PMID: 26948972; PMCID: PMC5083250.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    47. The sensitivity and significance of lateralized interictal slow activity on magnetoencephalography in focal epilepsy. Epilepsy Res. 2016 Mar; 121:21-8. Englot DJ, Nagarajan SS, Wang DD, Rolston JD, Mizuiri D, Honma SM, Mantle M, Tarapore PE, Knowlton RC, Chang EF, Kirsch HE. PMID: 26871959; PMCID: PMC4769925.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    48. Closed-loop feedback control and bifurcation analysis of epileptiform activity via optogenetic stimulation in a mathematical model of human cortex. Phys Rev E. 2016 Jan; 93(1):012416. Selvaraj P, Sleigh JW, Kirsch HE, Szeri AJ. PMID: 26871110.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    49. Phenotypic and imaging features of FLNA-negative patients with bilateral periventricular nodular heterotopia and epilepsy. Epilepsy Behav. 2015 Oct; 51:321-7. Fallil Z, Pardoe H, Bachman R, Cunningham B, Parulkar I, Shain C, Poduri A, Knowlton R, Kuzniecky R, EPGP Investigators. PMID: 26340046; PMCID: PMC4594191.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    50. 106 Functional Network Analysis in Surgical Epilepsy Patients Using Magnetoencephalography. Neurosurgery. 2015 Aug 1; 62(CN_suppl_1):198-198. Englot ED, Knowlton KR, Chang CE, Kirsch KH, Nagarajan NS. .
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    51. Surpassing the Target: How a Recruitment Campaign Transformed the Participant Accrual Trajectory in the Epilepsy Phenome/Genome Project. Clin Transl Sci. 2015 Oct; 8(5):518-25. McGovern K, Karn CF, Fox K, EPGP Investigators. PMID: 26176343; PMCID: PMC4626330.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    52. Global and regional functional connectivity maps of neural oscillations in focal epilepsy. Brain. 2015 Aug; 138(Pt 8):2249-62. Englot DJ, Hinkley LB, Kort NS, Imber BS, Mizuiri D, Honma SM, Findlay AM, Garrett C, Cheung PL, Mantle M, Tarapore PE, Knowlton RC, Chang EF, Kirsch HE, Nagarajan SS. PMID: 25981965; PMCID: PMC4840946.
      View in: PubMed   Mentions: 94     Fields:    Translation:Humans
    53. Epileptogenic zone localization using magnetoencephalography predicts seizure freedom in epilepsy surgery. Epilepsia. 2015 Jun; 56(6):949-58. Englot DJ, Nagarajan SS, Imber BS, Raygor KP, Honma SM, Mizuiri D, Mantle M, Knowlton RC, Kirsch HE, Chang EF. PMID: 25921215; PMCID: PMC4457690.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    54. A probabilistic method for determining cortical dynamics during seizures. J Comput Neurosci. 2015 Jun; 38(3):559-75. Dadok VM, Kirsch HE, Sleigh JW, Lopour BA, Szeri AJ. PMID: 25851500.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. Optogenetic induced epileptiform activity in a model human cortex. Springerplus. 2015; 4:155. Selvaraj P, Sleigh JW, Kirsch HE, Szeri AJ. PMID: 25897410; PMCID: PMC4395626.
      View in: PubMed   Mentions:
    56. Sex differences in seizure types and symptoms. Epilepsy Behav. 2014 Dec; 41:103-8. Carlson C, Dugan P, Kirsch HE, Friedman D, EPGP Investigators. PMID: 25461198; PMCID: PMC4267158.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    57. Auras in generalized epilepsy. Neurology. 2014 Oct 14; 83(16):1444-9. Dugan P, Carlson C, Bluvstein J, Chong DJ, Friedman D, Kirsch HE, EPGP Investigators. PMID: 25230998; PMCID: PMC4206156.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    58. A probabilistic framework for a physiological representation of dynamically evolving sleep state. J Comput Neurosci. 2014 Aug; 37(1):105-24. Dadok VM, Kirsch HE, Sleigh JW, Lopour BA, Szeri AJ. PMID: 24363031.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    59. Open loop optogenetic control of simulated cortical epileptiform activity. J Comput Neurosci. 2014 Jun; 36(3):515-25. Selvaraj P, Sleigh JW, Freeman WJ, Kirsch HE, Szeri AJ. PMID: 24174320.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    60. Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol. 2013 Sep 01; 70(9):1158-66. Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L. PMID: 23835471; PMCID: PMC4013391.
      View in: PubMed   Mentions: 298     Fields:    Translation:Humans
    61. De novo mutations in epileptic encephalopathies. Nature. 2013 Sep 12; 501(7466):217-21. Epi4K Consortium, Epilepsy Phenome/Genome Project, Allen AS, Berkovic SF, Cossette P, Delanty N, Dlugos D, Eichler EE, Epstein MP, Glauser T, Goldstein DB, Han Y, Heinzen EL, Hitomi Y, Howell KB, Johnson MR, Kuzniecky R, Lowenstein DH, Lu YF, Madou MR, Marson AG, Mefford HC, Esmaeeli Nieh S, O'Brien TJ, Ottman R, Petrovski S, Poduri A, Ruzzo EK, Scheffer IE, Sherr EH, Yuskaitis CJ, Abou-Khalil B, Alldredge BK, Bautista JF, Berkovic SF, Boro A, Cascino GD, Consalvo D, Crumrine P, Devinsky O, Dlugos D, Epstein MP, Fiol M, Fountain NB, French J, Friedman D, Geller EB, Glauser T, Glynn S, Haut SR, Hayward J, Helmers SL, Joshi S, Kanner A, Kirsch HE, Knowlton RC, Kossoff EH, Kuperman R, Kuzniecky R, Lowenstein DH, McGuire SM, Motika PV, Novotny EJ, Ottman R, Paolicchi JM, Parent JM, Park K, Poduri A, Scheffer IE, Shellhaas RA, Sherr EH, Shih JJ, Singh R, Sirven J, Smith MC, Sullivan J, Lin Thio L, Venkat A, Vining EP, Von Allmen GK, Weisenberg JL, Widdess-Walsh P, Winawer MR. PMID: 23934111; PMCID: PMC3773011.
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    62. The epilepsy phenome/genome project. Clin Trials. 2013 Aug; 10(4):568-86. EPGP Collaborative, Abou-Khalil B, Alldredge B, Bautista J, Berkovic S, Bluvstein J, Boro A, Cascino G, Consalvo D, Cristofaro S, Crumrine P, Devinsky O, Dlugos D, Epstein M, Fahlstrom R, Fiol M, Fountain N, Fox K, French J, Freyer Karn C, Friedman D, Geller E, Glauser T, Glynn S, Haas K, Haut S, Hayward J, Helmers S, Joshi S, Kanner A, Kirsch H, Knowlton R, Kossoff E, Kuperman R, Kuzniecky R, Lowenstein D, McGuire S, Motika P, Nesbitt G, Novotny E, Ottman R, Paolicchi J, Parent J, Park K, Poduri A, Risch N, Sadleir L, Scheffer I, Shellhaas R, Sherr E, Shih JJ, Shinnar S, Singh R, Sirven J, Smith M, Sullivan J, Thio LL, Venkat A, Vining E, von Allmen G, Weisenberg J, Widdess-Walsh P, Winawer M. PMID: 23818435; PMCID: PMC5951634.
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    63. Evidence for a shared genetic susceptibility to migraine and epilepsy. Epilepsia. 2013 Feb; 54(2):288-95. Winawer MR, Connors R, EPGP Investigators. PMID: 23294289; PMCID: PMC3566298.
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    64. Magnetoencephalographic imaging of resting-state functional connectivity predicts postsurgical neurological outcome in brain gliomas. Neurosurgery. 2012 Nov; 71(5):1012-22. Tarapore PE, Martino J, Guggisberg AG, Owen J, Honma SM, Findlay A, Berger MS, Kirsch HE, Nagarajan SS. PMID: 22895403; PMCID: PMC3761085.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    65. Interpretation of seizure evolution pathways via a mean-field cortical model. BMC Neuroscience. 2012 Jul 1; 13(Suppl 1):p95. Dadok DV, Szeri SA, Kirsch KH, Sleigh SJ, Lopour LB. .
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    66. What can be learned from high-resolution sleep data using ECoG. BMC Neuroscience. 2012 Jul 1; 13(Suppl 1):p94. Dadok DV, Szeri SA, Kirsch KH, Sleigh SJ, Zak ZR, Lopour LB. .
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    67. Subclinical epileptiform activity in Alzheimer's disease. Alzheimer's & Dementia. 2012 Jul 1; 8(4):p395-p396. Vossel VK, Beagle BA, Hegde HM, Mantle MM, Kirsch KH, Garcia GP, Honma HS, Findlay FA, Rabinovici RG, Jagust JW, Nagarajan NS, Miller MB, Roberson RE, Mucke ML. .
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    68. Gustatory cortical lesions affect motivation for snack foods. Cogn Neurosci. 2012; 3(2):131-8. Knutson KM, Krueger F, Dal Monte O, Raymont V, Snyder AD, Kirsch HE, Wassermann EM, Grafman J. PMID: 24168694.
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    69. The Epilepsy Phenome/Genome Project (EPGP) informatics platform. Int J Med Inform. 2013 Apr; 82(4):248-59. Nesbitt G, McKenna K, Mays V, Carpenter A, Miller K, Williams M, EPGP Investigators. PMID: 22579394; PMCID: PMC3655424.
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    70. Hemispheric asymmetries and prosodic emotion recognition deficits in Parkinson's disease. Neuropsychologia. 2012 Jul; 50(8):1936-45. Ventura MI, Baynes K, Sigvardt KA, Unruh AM, Acklin SS, Kirsch HE, Disbrow EA. PMID: 22564479.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    71. Dynamics of hemispheric dominance for language assessed by magnetoencephalographic imaging. Ann Neurol. 2012 May; 71(5):668-86. Findlay AM, Ambrose JB, Cahn-Weiner DA, Houde JF, Honma S, Hinkley LB, Berger MS, Nagarajan SS, Kirsch HE. PMID: 22522481; PMCID: PMC3380661.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    72. The Alliance for Clinical Education Guidebook for Clerkship Directors. Longitudinal Integrated Clerkships. 2012; 173-224. Poncelet A, Hirsh D, Arky R, Mazotti L, Ogur B, Bor D, Brooks K, Erickson J, Hansen L, Wamsley M, Shore W, Cohen P, Kirsch H, Elvin D, Gaufberg E, Cave M-T, Clandinin J, Cave A, Batalden M, Lai C, Polevoi S, Stein J, Ghosh A, Maa J, Theodore P, Park P, Bokser S, Robertson P, Griswold T, Meyer R, Schauer R, Konkin J, Strasser S, Strasser R, Worley P, Greenhill J, Hauer K, Krupat E, Tong L, Teherani A, Krupat E.
    73. American Clinical Magnetoencephalography Society Clinical Practice Guideline 2: presurgical functional brain mapping using magnetic evoked fields. J Clin Neurophysiol. 2011 Aug; 28(4):355-61. Burgess RC, Funke ME, Bowyer SM, Lewine JD, Kirsch HE, Bagic AI, ACMEGS Clinical Practice Guideline (CPG) Committee, . PMID: 21811122; PMCID: PMC3366725.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    74. Development of a longitudinal integrated clerkship at an academic medical center. Med Educ Online. 2011 Apr 04; 16. Poncelet A, Bokser S, Calton B, Hauer KE, Kirsch H, Jones T, Lai CJ, Mazotti L, Shore W, Teherani A, Tong L, Wamsley M, Robertson P. PMID: 21475642; PMCID: PMC3071870.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    75. Resting functional connectivity in patients with brain tumors in eloquent areas. Ann Neurol. 2011 Mar; 69(3):521-32. Martino J, Honma SM, Findlay AM, Guggisberg AG, Owen JP, Kirsch HE, Berger MS, Nagarajan SS. PMID: 21400562; PMCID: PMC4090361.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    76. Single-trial speech suppression of auditory cortex activity in humans. J Neurosci. 2010 Dec 08; 30(49):16643-50. Flinker A, Chang EF, Kirsch HE, Barbaro NM, Crone NE, Knight RT. PMID: 21148003; PMCID: PMC3010242.
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    77. Improving integration of clinical clerkship didactic curriculum. Medical Education Development. 2010 Dec 2; 1(1):1. Mazotti ML, O'Brien OB, Kirsch KH. .
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    78. A continuous mapping of sleep states through association of EEG with a mesoscale cortical model. J Comput Neurosci. 2011 Apr; 30(2):471-87. Lopour BA, Tasoglu S, Kirsch HE, Sleigh JW, Szeri AJ. PMID: 20809258; PMCID: PMC3058368.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    79. Cortical spatio-temporal dynamics underlying phonological target detection in humans. J Cogn Neurosci. 2011 Jun; 23(6):1437-46. Chang EF, Edwards E, Nagarajan SS, Fogelson N, Dalal SS, Canolty RT, Kirsch HE, Barbaro NM, Knight RT. PMID: 20465359; PMCID: PMC3895406.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    80. Noninvasive testing, early surgery, and seizure freedom in tuberous sclerosis complex. Neurology. 2010 Feb 02; 74(5):392-8. Wu JY, Salamon N, Kirsch HE, Mantle MM, Nagarajan SS, Kurelowech L, Aung MH, Sankar R, Shields WD, Mathern GW. PMID: 20124204; PMCID: PMC2816007.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    81. Interictal MEG/MSI in intractable mesial temporal lobe epilepsy: spike yield and characterization. Clin Neurophysiol. 2010 Mar; 121(3):325-31. Kaiboriboon K, Nagarajan S, Mantle M, Kirsch HE. PMID: 20064741; PMCID: PMC2821956.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    82. Spatiotemporal imaging of cortical activation during verb generation and picture naming. Neuroimage. 2010 Mar; 50(1):291-301. Edwards E, Nagarajan SS, Dalal SS, Canolty RT, Kirsch HE, Barbaro NM, Knight RT. PMID: 20026224; PMCID: PMC2957470.
      View in: PubMed   Mentions: 106     Fields:    Translation:Humans
    83. Magnetic source imaging for the surgical evaluation of electroencephalography-confirmed secondary bilateral synchrony in intractable epilepsy. J Neurosurg. 2009 Dec; 111(6):1248-56. Chang EF, Nagarajan SS, Mantle M, Barbaro NM, Kirsch HE. PMID: 19575574; PMCID: PMC3151560.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    84. Model and data-driven representations of the sleep cycle using locally linear embedding. BMC Neuroscience. 2009 Sep 1; 10(Suppl 1):p294. Lopour LB, Kirsch KH, Sleigh SJ, Szeri SA. .
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    85. The effects of epilepsy and its treatments on affect and emotion. Neurocase. 2009 Jun; 15(3):206-16. Hixson JD, Kirsch HE. PMID: 19204849.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    86. Propofol: Pro- or Anticonvulsant Drug?. Anesthesia & Analgesia. 2009 Jun 1; 108(6):1994. Sleigh SJ, Voss VL, Barnard BJ, Kirsch KH. .
      View in: Publisher Site   Mentions:
    87. The howling cortex: seizures and general anesthetic drugs. Anesth Analg. 2008 Nov; 107(5):1689-703. Voss LJ, Sleigh JW, Barnard JP, Kirsch HE. PMID: 18931234.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    88. Tracing the roots and routes of cognitive dysfunction in epilepsy. Neurology. 2008 Dec 02; 71(23):1854-5. Kirsch HE, Grossman M. PMID: 18946000.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    89. Preoperative localization of hand motor cortex by adaptive spatial filtering of magnetoencephalography data. J Neurosurg. 2008 Aug; 109(2):228-37. Nagarajan S, Kirsch H, Lin P, Findlay A, Honma S, Berger MS. PMID: 18671634.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    90. Localization of neurosurgically implanted electrodes via photograph-MRI-radiograph coregistration. J Neurosci Methods. 2008 Sep 15; 174(1):106-15. Dalal SS, Edwards E, Kirsch HE, Barbaro NM, Knight RT, Nagarajan SS. PMID: 18657573; PMCID: PMC2695765.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    91. Emergent network topology at seizure onset in humans. Epilepsy Res. 2008 May; 79(2-3):173-86. Kramer MA, Kolaczyk ED, Kirsch HE. PMID: 18359200.
      View in: PubMed   Mentions: 70     Fields:    Translation:Humans
    92. Mapping functional connectivity in patients with brain lesions. Ann Neurol. 2008 Feb; 63(2):193-203. Guggisberg AG, Honma SM, Findlay AM, Dalal SS, Kirsch HE, Berger MS, Nagarajan SS. PMID: 17894381; PMCID: PMC3646715.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    93. Five-dimensional neuroimaging: localization of the time-frequency dynamics of cortical activity. Neuroimage. 2008 May 01; 40(4):1686-700. Dalal SS, Guggisberg AG, Edwards E, Sekihara K, Findlay AM, Canolty RT, Berger MS, Knight RT, Barbaro NM, Kirsch HE, Nagarajan SS. PMID: 18356081; PMCID: PMC2426929.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    94. Spatiotemporal dynamics of word processing in the human brain. Front Neurosci. 2007 Nov; 1(1):185-96. Canolty RT, Soltani M, Dalal SS, Edwards E, Dronkers NF, Nagarajan SS, Kirsch HE, Barbaro NM, Knight RT. PMID: 18982128; PMCID: PMC2518055.
      View in: PubMed   Mentions: 122  
    95. Fast oscillations associated with interictal spikes localize the epileptogenic zone in patients with partial epilepsy. Neuroimage. 2008 Jan 15; 39(2):661-8. Guggisberg AG, Kirsch HE, Mantle MM, Barbaro NM, Nagarajan SS. PMID: 17977022; PMCID: PMC2742724.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    96. Predicting the location of mouth motor cortex in patients with brain tumors by using somatosensory evoked field measurements. J Neurosurg. 2007 Sep; 107(3):481-7. Kirsch HE, Zhu Z, Honma S, Findlay A, Berger MS, Nagarajan SS. PMID: 17886544.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    97. Concordance between routine interictal magnetoencephalography and simultaneous scalp electroencephalography in a sample of patients with epilepsy. J Clin Neurophysiol. 2007 Jun; 24(3):215-31. Kirsch HE, Mantle M, Nagarajan SS. PMID: 17545825; PMCID: PMC4096347.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    98. Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1. Ann Neurol. 2007 Feb; 61(2):139-52. Wang Y, Greenwood JS, Calcagnotto ME, Kirsch HE, Barbaro NM, Baraban SC. PMID: 17279540.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    99. GL Krauss, RS Fisher (Eds.). The Johns Hopkins Atlas of Digital EEG: An Interactive Training Guide. The '10-20' system and cortical topography. 2007. Kirsch HE, Crone NE.
    100. Spatial localization of cortical time-frequency dynamics. Annu Int Conf IEEE Eng Med Biol Soc. 2007; 2007:4941-4. Dalal SS, Guggisberg AG, Edwards E, Sekihara K, Findlay AM, Canolty RT, Knight RT, Barbaro NM, Kirsch HE, Nagarajan SS. PMID: 18003115.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    101. Mechanisms of seizure propagation in a cortical model. J Comput Neurosci. 2007 Feb; 22(1):63-80. Kramer MA, Szeri AJ, Sleigh JW, Kirsch HE. PMID: 16998642.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    102. High gamma power is phase-locked to theta oscillations in human neocortex. Science. 2006 Sep 15; 313(5793):1626-8. Canolty RT, Edwards E, Dalal SS, Soltani M, Nagarajan SS, Kirsch HE, Berger MS, Barbaro NM, Knight RT. PMID: 16973878; PMCID: PMC2628289.
      View in: PubMed   Mentions: 1039     Fields:    Translation:Humans
    103. Automated localization of magnetoencephalographic interictal spikes by adaptive spatial filtering. Clin Neurophysiol. 2006 Oct; 117(10):2264-71. Kirsch HE, Robinson SE, Mantle M, Nagarajan S. PMID: 16893680.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    104. Bifurcation control of a seizing human cortex. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Apr; 73(4 Pt 1):041928. Kramer MA, Lopour BA, Kirsch HE, Szeri AJ. PMID: 16711857.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    105. Complex visual hallucinations as post-ictal cortical release phenomena. Neurocase. 2006 Apr; 12(2):107-10. Josephson SA, Kirsch HE. PMID: 16714243.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    106. Social cognition and epilepsy surgery. Epilepsy Behav. 2006 Feb; 8(1):71-80. Kirsch HE. PMID: 16253567.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    107. Limitations of Wada memory asymmetry as a predictor of outcomes after temporal lobectomy. Neurology. 2005 Sep 13; 65(5):676-80. Kirsch HE, Walker JA, Winstanley FS, Hendrickson R, Wong ST, Barbaro NM, Laxer KD, Garcia PA. PMID: 16157898.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    108. [Human biomonitoring investigations of organochlorine compounds -- PCB, DDE, HCB, beta- and gamma-HCH, PCDD/PCDF, Dioxin-like PCB's and polybrominated biphenyl ethers]. Gesundheitswesen. 2005 Apr; 67(4):302-11. Gabrio T, Broser S, Erdinger L, Felder-Kennel A, Fichtner G, Häberle E, Herrmann T, Kirsch H, Kouros B, Link B, Maisner V, Mann V, Päpke O, Piechotowski I, Rzonca E, Schick KH, Schrimpf M, Schröder S, Spöker-Maas K, Weidner U, Wuthe J, Zöllner I, Zöltzer D. PMID: 15856391.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    109. Pathological pattern formation and cortical propagation of epileptic seizures. J R Soc Interface. 2005 Mar 22; 2(2):113-27. Kramer MA, Kirsch HE, Szeri AJ. PMID: 16849171; PMCID: PMC1578262.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    110. Localization of interictal spikes using SAM(g2) and dipole fit. Neurol Clin Neurophysiol. 2004 Nov 30; 2004:74. Robinson SE, Nagarajan SS, Mantle M, Gibbons V, Kirsch H. PMID: 16012648; PMCID: PMC4041981.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    111. Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion. Epilepsy Behav. 2004 Jun; 5(3):407-10. Kirsch HE, Sepkuty JP, Crone NE. PMID: 15145312.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    112. The utility of a federated web-based information management system in an epilepsy center. Neuroinformatics. 2004; 2(1):119-21. Kirsch HE. PMID: 15067171.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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