Joanna Phillips, MD, PhD

Title(s)Professor, Neurological Surgery
SchoolSchool of Medicine
Address1450 Third St
San Francisco CA 94158
Phone415-514-4929
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division
    University of PennsylvaniaM.D.2002School of Medicine
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    UCSF2013Nominated for UCSF School of Medicine Essential Core Teaching Award
    UCSF2015Excellence in Teaching Award in medical education from the Haile T. Debas Academy of Medical Educato

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Mitigation of preanalytic factors influencing brain tumor protein phosphorylation
    NIH U01CA229345Apr 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Heparan sulfate proteoglycans as critical regulators of brain cancer malignancy
    NIH R01NS081117Sep 30, 2012 - Jun 30, 2018
    Role: Principal Investigator
    Extracellular Sulfatases As Novel Biomarkers For Early Detection of Cancer
    NIH U01CA168878Aug 16, 2012 - Jun 30, 2018
    Role: Co-Principal Investigator
    Biophysical and molecular dialogue of glioma cells and the brain microenvironment
    NIH U54CA163155Sep 26, 2011 - Jul 31, 2016
    Role: Co-Investigator
    The role of microglia and macrophages in the development of brain tumors
    NIH K08NS063456Jul 1, 2008 - Jun 30, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. PI3K/AKT/mTOR signaling pathway activity in IDH-mutant diffuse glioma and clinical implications. Neuro Oncol. 2022 Sep 01; 24(9):1471-1481. Mohamed E, Kumar A, Zhang Y, Wang AS, Chen K, Lim Y, Shai A, Taylor JW, Clarke J, Hilz S, Berger MS, Solomon DA, Costello JF, Molinaro AM, Phillips JJ. PMID: 35287169; PMCID: PMC9435510.
      View in: PubMed   Mentions:    Fields:    
    2. Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma. J Neuropathol Exp Neurol. 2022 Jul 19; 81(8):650-657. Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, Hervey-Jumper SL, Gupta N, Oberheim Bush NA, Raleigh DR, Bollen A, Tihan T, Pekmezci M, Solomon DA, Phillips JJ, Perry A. PMID: 35703914; PMCID: PMC9297094.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. CXCL14 Promotes a Robust Brain Tumor-Associated Immune Response in Glioma. Clin Cancer Res. 2022 07 01; 28(13):2898-2910. Kumar A, Mohamed E, Tong S, Chen K, Mukherjee J, Lim Y, Wong CM, Boosalis Z, Shai A, Pieper RO, Gupta N, Perry A, Bollen AW, Molinaro AM, Solomon DA, Shieh JTC, Phillips JJ. PMID: 35511927; PMCID: PMC9250623.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Spectroscopic imaging of D-2-hydroxyglutarate and other metabolites in pre-surgical patients with IDH-mutant lower-grade gliomas. J Neurooncol. 2022 Aug; 159(1):43-52. Autry AW, Lafontaine M, Jalbert L, Phillips E, Phillips JJ, Villanueva-Meyer J, Berger MS, Chang SM, Li Y. PMID: 35672531; PMCID: PMC9325821.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet. 2022 05; 54(5):649-659. Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. PMID: 35534562; PMCID: PMC9374001.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    6. Prospective genomically-guided identification of 'early/evolving' and 'undersampled' IDH-wildtype glioblastoma leads to improved clinical outcomes. Neuro Oncol. 2022 Apr 08. Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen AW, Aghi MK, Theodosopoulos P, Chang EF, Hervey-Jumper SL, Berger MS, Clarke JL, Chang SM, Molinaro AM, Solomon DA. PMID: 35395677.
      View in: PubMed   Mentions:    Fields:    
    7. Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging. Neuro Oncol. 2022 04 01; 24(4):639-652. Cluceru J, Interian Y, Phillips JJ, Molinaro AM, Luks TL, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Shai A, Chunduru P, Pedoia V, Villanueva-Meyer JE, Chang SM, Lupo JM. PMID: 34653254; PMCID: PMC8972294.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. In-Depth Matrisome and Glycoproteomic Analysis of Human Brain Glioblastoma Versus Control Tissue. Mol Cell Proteomics. 2022 04; 21(4):100216. Sethi MK, Downs M, Shao C, Hackett WE, Phillips JJ, Zaia J. PMID: 35202840; PMCID: PMC8957055.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas. J Clin Invest. 2022 02 01; 132(3). Ogino H, Taylor JW, Nejo T, Gibson D, Watchmaker PB, Okada K, Saijo A, Tedesco MR, Shai A, Wong CM, Rabbitt JE, Olin MR, Moertel CL, Nishioka Y, Salazar AM, Molinaro AM, Phillips JJ, Butowski NA, Clarke JL, Oberheim Bush NA, Hervey-Jumper SL, Theodosopoulos P, Chang SM, Berger MS, Okada H. PMID: 34882581; PMCID: PMC8803342.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    10. Cellular architecture of human brain metastases. Cell. 2022 02 17; 185(4):729-745.e20. Gonzalez H, Mei W, Robles I, Hagerling C, Allen BM, Hauge Okholm TL, Nanjaraj A, Verbeek T, Kalavacherla S, van Gogh M, Georgiou S, Daras M, Phillips JJ, Spitzer MH, Roose JP, Werb Z. PMID: 35063085; PMCID: PMC8857062.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. Association of Neurological Impairment on the Relative Benefit of Maximal Extent of Resection in Chemoradiation-Treated Newly Diagnosed Isocitrate Dehydrogenase Wild-Type Glioblastoma. Neurosurgery. 2022 01 01; 90(1):124-130. Aabedi AA, Young JS, Zhang Y, Ammanuel S, Morshed RA, Dalle Ore C, Brown D, Phillips JJ, Oberheim Bush NA, Taylor JW, Butowski N, Clarke J, Chang SM, Aghi M, Molinaro AM, Berger MS, Hervey-Jumper SL. PMID: 34982879.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Measuring Sulfatase Expression and Invasion in Glioblastoma. Methods Mol Biol. 2022; 2303:415-425. Wade A, Engler JR, Tran VM, Phillips JJ. PMID: 34626397.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma. Acta Neuropathol. 2022 02; 143(2):283-286. Lucas CG, Abdullaev Z, Bruggers CS, Mirchia K, Whipple NS, Alashari MM, Lowichik A, Cheshier S, Phillips JJ, Devine P, Solomon DA, Quezado M, Aldape KD, Perry A. PMID: 34910220; PMCID: PMC8742815.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Reply to Stummer, W.; Thomas, C. Comment on "Hosmann et al. 5-ALA Fluorescence Is a Powerful Prognostic Marker during Surgery of Low-Grade Gliomas (WHO Grade II)-Experience at Two Specialized Centers. Cancers 2021, 13, 2540". Cancers (Basel). 2021 Nov 15; 13(22). Hosmann A, Millesi M, Wadiura LI, Kiesel B, Mercea PA, Mischkulnig M, Borkovec M, Furtner J, Roetzer T, Wolfsberger S, Phillips JJ, Berghoff AS, Hervey-Jumper S, Berger MS, Widhalm G. PMID: 34830859; PMCID: PMC8616458.
      View in: PubMed   Mentions:
    15. ATRX regulates glial identity and the tumor microenvironment in IDH-mutant glioma. Genome Biol. 2021 11 11; 22(1):311. Babikir H, Wang L, Shamardani K, Catalan F, Sudhir S, Aghi MK, Raleigh DR, Phillips JJ, Diaz AA. PMID: 34763709; PMCID: PMC8588616.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. Diffuse hemispheric glioma, H3 G34-mutant: Genomic landscape of a new tumor entity and prospects for targeted therapy. Neuro Oncol. 2021 11 02; 23(11):1974-1976. Lucas CG, Mueller S, Reddy A, Taylor JW, Oberheim Bush NA, Clarke JL, Chang SM, Gupta N, Berger MS, Perry A, Phillips JJ, Solomon DA. PMID: 34519829; PMCID: PMC8628364.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas. Neuro Oncol. 2021 11 02; 23(11):1872-1884. Yu Y, Villanueva-Meyer J, Grimmer MR, Hilz S, Solomon DA, Choi S, Wahl M, Mazor T, Hong C, Shai A, Phillips JJ, Wainer BH, McDermott M, Haas-Kogan D, Taylor JW, Butowski N, Clarke JL, Berger MS, Molinaro AM, Chang SM, Costello JF, Oberheim Bush NA. PMID: 33823014; PMCID: PMC8563321.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    18. Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas. Sci Transl Med. 2021 Oct 06; 13(614):eabc0497. Panwalkar P, Tamrazi B, Dang D, Chung C, Sweha S, Natarajan SK, Pun M, Bayliss J, Ogrodzinski MP, Pratt D, Mullan B, Hawes D, Yang F, Lu C, Sabari BR, Achreja A, Heon J, Animasahun O, Cieslik M, Dunham C, Yip S, Hukin J, Phillips JJ, Bornhorst M, Griesinger AM, Donson AM, Foreman NK, Garton HJL, Heth J, Muraszko K, Nazarian J, Koschmann C, Jiang L, Filbin MG, Nagrath D, Kool M, Korshunov A, Pfister SM, Gilbertson RJ, Allis CD, Chinnaiyan AM, Lunt SY, Blüml S, Judkins AR, Venneti S. PMID: 34613815; PMCID: PMC8762577.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    19. The effects of palbociclib in combination with radiation in preclinical models of aggressive meningioma. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab085. Horbinski C, Xi G, Wang Y, Hashizume R, Gopalakrishnan M, Phillips JJ, Houghton P, James CD, Kalapurakal JA. PMID: 34345820; PMCID: PMC8325754.
      View in: PubMed   Mentions: 1  
    20. 5-ALA Fluorescence Is a Powerful Prognostic Marker during Surgery of Low-Grade Gliomas (WHO Grade II)-Experience at Two Specialized Centers. Cancers (Basel). 2021 May 21; 13(11). Hosmann A, Millesi M, Wadiura LI, Kiesel B, Mercea PA, Mischkulnig M, Borkovec M, Furtner J, Roetzer T, Wolfsberger S, Phillips JJ, Berghoff AS, Hervey-Jumper S, Berger MS, Widhalm G. PMID: 34064222; PMCID: PMC8196836.
      View in: PubMed   Mentions: 6  
    21. Immune cell analysis of pilocytic astrocytomas reveals sexually dimorphic brain region-specific differences in T-cell content. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab068. Chen J, Sinha N, Cobb O, Liu C, Ersen A, Phillips JJ, Tihan T, Gutmann DH, Dahiya S. PMID: 34286276; PMCID: PMC8284620.
      View in: PubMed   Mentions:
    22. Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination. Nat Commun. 2021 03 26; 12(1):1923. Saraswat D, Shayya HJ, Polanco JJ, Tripathi A, Welliver RR, Pol SU, Seidman RA, Broome JE, O'Bara MA, van Kuppervelt TH, Phillips JJ, Dutta R, Sim FJ. PMID: 33772011; PMCID: PMC7998003.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    23. The transcriptional landscape of Shh medulloblastoma. Nat Commun. 2021 03 19; 12(1):1749. Skowron P, Farooq H, Cavalli FMG, Morrissy AS, Ly M, Hendrikse LD, Wang EY, Djambazian H, Zhu H, Mungall KL, Trinh QM, Zheng T, Dai S, Stucklin ASG, Vladoiu MC, Fong V, Holgado BL, Nor C, Wu X, Abd-Rabbo D, Bérubé P, Wang YC, Luu B, Suarez RA, Rastan A, Gillmor AH, Lee JJY, Zhang XY, Daniels C, Dirks P, Malkin D, Bouffet E, Tabori U, Loukides J, Doz FP, Bourdeaut F, Delattre OO, Masliah-Planchon J, Ayrault O, Kim SK, Meyronet D, Grajkowska WA, Carlotti CG, de Torres C, Mora J, Eberhart CG, Van Meir EG, Kumabe T, French PJ, Kros JM, Jabado N, Lach B, Pollack IF, Hamilton RL, Rao AAN, Giannini C, Olson JM, Bognár L, Klekner A, Zitterbart K, Phillips JJ, Thompson RC, Cooper MK, Rubin JB, Liau LM, Garami M, Hauser P, Li KKW, Ng HK, Poon WS, Yancey Gillespie G, Chan JA, Jung S, McLendon RE, Thompson EM, Zagzag D, Vibhakar R, Ra YS, Garre ML, Schüller U, Shofuda T, Faria CC, López-Aguilar E, Zadeh G, Hui CC, Ramaswamy V, Bailey SD, Jones SJ, Mungall AJ, Moore RA, Calarco JA, Stein LD, Bader GD, Reimand J, Ragoussis J, Weiss WA, Marra MA, Suzuki H, Taylor MD. PMID: 33741928; PMCID: PMC7979819.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    24. Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1). Acta Neuropathol. 2021 04; 141(4):605-617. Fisher MJ, Jones DTW, Li Y, Guo X, Sonawane PS, Waanders AJ, Phillips JJ, Weiss WA, Resnick AC, Gosline S, Banerjee J, Guinney J, Gnekow A, Kandels D, Foreman NK, Korshunov A, Ryzhova M, Massimi L, Gururangan S, Kieran MW, Wang Z, Fouladi M, Sato M, Øra I, Holm S, Markham SJ, Beck P, Jäger N, Wittmann A, Sommerkamp AC, Sahm F, Pfister SM, Gutmann DH. PMID: 33585982.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    25. The evolution of alternative splicing in glioblastoma under therapy. Genome Biol. 2021 01 26; 22(1):48. Wang L, Shamardani K, Babikir H, Catalan F, Nejo T, Chang S, Phillips JJ, Okada H, Diaz AA. PMID: 33499924; PMCID: PMC7835670.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    26. A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042). Pediatr Blood Cancer. 2021 04; 68(4):e28879. Van Mater D, Gururangan S, Becher O, Campagne O, Leary S, Phillips JJ, Huang J, Lin T, Poussaint TY, Goldman S, Baxter P, Dhall G, Robinson G, DeWire-Schottmiller M, Hwang EI, Stewart CF, Onar-Thomas A, Dunkel IJ, Fouladi M. PMID: 33405376; PMCID: PMC8414988.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    27. Non-invasive assessment of telomere maintenance mechanisms in brain tumors. Nat Commun. 2021 01 04; 12(1):92. Viswanath P, Batsios G, Mukherjee J, Gillespie AM, Larson PEZ, Luchman HA, Phillips JJ, Costello JF, Pieper RO, Ronen SM. PMID: 33397920; PMCID: PMC7782549.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    28. Synthesis and Screening of α-Xylosides in Human Glioblastoma Cells. Mol Pharm. 2021 01 04; 18(1):451-460. Kalita M, Villanueva-Meyer J, Ohkawa Y, Kalyanaraman C, Chen K, Mohamed E, Parker MFL, Jacobson MP, Phillips JJ, Evans MJ, Wilson DM. PMID: 33315406; PMCID: PMC8483608.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Development of novel monoclonal antibodies and immunoassays for sensitive and specific detection of SULF1 endosulfatase. Biochim Biophys Acta Gen Subj. 2021 02; 1865(2):129802. Yang YW, Phillips JJ, Jablons DM, Lemjabbar-Alaoui H. PMID: 33276062; PMCID: PMC7752833.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    30. MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence. Neuro Oncol. 2020 11 26; 22(11):1580-1590. Mathur R, Zhang Y, Grimmer MR, Hong C, Zhang M, Bollam S, Petrecca K, Clarke J, Berger MS, Phillips JJ, Oberheim-Bush NA, Molinaro AM, Chang SM, Costello JF. PMID: 32166314; PMCID: PMC8444710.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    31. Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adults. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa142. Schulte JD, Buerki RA, Lapointe S, Molinaro AM, Zhang Y, Villanueva-Meyer JE, Perry A, Phillips JJ, Tihan T, Bollen AW, Pekmezci M, Butowski N, Oberheim Bush NA, Taylor JW, Chang SM, Theodosopoulos P, Aghi MK, Hervey-Jumper SL, Berger MS, Solomon DA, Clarke JL. PMID: 33354667; PMCID: PMC7739048.
      View in: PubMed   Mentions: 12  
    32. Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas. Neuro Oncol. 2020 10 14; 22(10):1516-1526. Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM. PMID: 32319527; PMCID: PMC7566399.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM. Mol Cancer Res. 2021 01; 19(1):150-161. Ohkawa Y, Wade A, Lindberg OR, Chen KY, Tran VM, Brown SJ, Kumar A, Kalita M, James CD, Phillips JJ. PMID: 33028660; PMCID: PMC7785678.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    34. Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor. Acta Neuropathol Commun. 2020 08 28; 8(1):151. Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, Cooney T, Cham E, Jin LW, Khatib Z, Maher O, Chamyan G, Brathwaite C, Bannykh S, Mueller S, Kline CN, Banerjee A, Reddy A, Taylor JW, Clarke JL, Oberheim Bush NA, Butowski N, Gupta N, Auguste KI, Sun PP, Roland JL, Raffel C, Aghi MK, Theodosopoulos P, Chang E, Hervey-Jumper S, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Chang S, Berger MS, Perry A, Solomon DA. PMID: 32859279; PMCID: PMC7456392.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    35. Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa088. Jones LE, Hilz S, Grimmer MR, Mazor T, Najac C, Mukherjee J, McKinney A, Chow T, Pieper RO, Ronen SM, Chang SM, Phillips JJ, Costello JF. PMID: 32904945; PMCID: PMC7462278.
      View in: PubMed   Mentions: 7  
    36. Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa078. Blomquist MR, Ensign SF, D'Angelo F, Phillips JJ, Ceccarelli M, Peng S, Halperin RF, Caruso FP, Garofano L, Byron SA, Liang WS, Craig DW, Carpten JD, Prados MD, Trent JM, Berens ME, Iavarone A, Dhruv H, Tran NL. PMID: 32743548; PMCID: PMC7388612.
      View in: PubMed   Mentions: 2  
    37. Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathol. 2020 06; 139(6):1071-1088. Mondal G, Lee JC, Ravindranathan A, Villanueva-Meyer JE, Tran QT, Allen SJ, Barreto J, Gupta R, Doo P, Van Ziffle J, Onodera C, Devine P, Grenert JP, Samuel D, Li R, Metrock LK, Jin LW, Antony R, Alashari M, Cheshier S, Whipple NS, Bruggers C, Raffel C, Gupta N, Kline CN, Reddy A, Banerjee A, Hall MD, Mehta MP, Khatib Z, Maher OM, Brathwaite C, Pekmezci M, Phillips JJ, Bollen AW, Tihan T, Lucas JT, Broniscer A, Berger MS, Perry A, Orr BA, Solomon DA. PMID: 32303840; PMCID: PMC7792550.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    38. Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma. JAMA Oncol. 2020 04 01; 6(4):495-503. Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C, Barnholtz-Sloan J, Sloan AE, Erickson BJ, Decker PA, Kosel ML, LaChance D, Eckel-Passow J, Jenkins R, Villanueva-Meyer J, Rice T, Wrensch M, Wiencke JK, Oberheim Bush NA, Taylor J, Butowski N, Prados M, Clarke J, Chang S, Chang E, Aghi M, Theodosopoulos P, McDermott M, Berger MS. PMID: 32027343; PMCID: PMC7042822.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    39. Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features. Acta Neuropathol. 2020 05; 139(5):953-957. Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, Bruggers CS, Alashari M, Wetmore C, Garg S, Dishop M, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Berger MS, Costello JF, Perry A, Solomon DA. PMID: 32157385; PMCID: PMC7183424.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker. Acta Neuropathol. 2020 03; 139(3):597-600. Pekmezci M, Phillips JJ, Dirilenoglu F, Atasever-Rezanko T, Tihan T, Solomon D, Bollen A, Perry A. PMID: 31912209.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    41. Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas. PLoS One. 2019; 14(12):e0219724. Berens ME, Sood A, Barnholtz-Sloan JS, Graf JF, Cho S, Kim S, Kiefer J, Byron SA, Halperin RF, Nasser S, Adkins J, Cuyugan L, Devine K, Ostrom Q, Couce M, Wolansky L, McDonough E, Schyberg S, Dinn S, Sloan AE, Prados M, Phillips JJ, Nelson SJ, Liang WS, Al-Kofahi Y, Rusu M, Zavodszky MI, Ginty F. PMID: 31881020; PMCID: PMC6934292.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    42. Cooperative Blockade of PKCα and JAK2 Drives Apoptosis in Glioblastoma. Cancer Res. 2020 02 15; 80(4):709-718. Wong RA, Luo X, Lu M, An Z, Haas-Kogan DA, Phillips JJ, Shokat KM, Weiss WA, Fan QW. PMID: 31806641; PMCID: PMC7024655.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    43. EGFR amplification status for clinical trial inclusion: where do we draw the line? Neuro Oncol. 2019 10 09; 21(10):1215-1216. Molinaro AM, Phillips JJ. PMID: 31504815; PMCID: PMC6784265.
      View in: PubMed   Mentions:    Fields:    
    44. The Phenotypes of Proliferating Glioblastoma Cells Reside on a Single Axis of Variation. Cancer Discov. 2019 12; 9(12):1708-1719. Wang L, Babikir H, Müller S, Yagnik G, Shamardani K, Catalan F, Kohanbash G, Alvarado B, Di Lullo E, Kriegstein A, Shah S, Wadhwa H, Chang SM, Phillips JJ, Aghi MK, Diaz AA. PMID: 31554641; PMCID: PMC7161589.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    45. Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas. Acta Neuropathol. 2019 11; 138(5):877-881. Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, McDermott M, Berger M, Raffel C, Gupta N, Sun PP, Li Y, Shah V, Cha S, Braunstein S, Raleigh DR, Samuel D, Scharnhorst D, Fata C, Guo H, Moes G, Kim JYH, Koschmann C, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Phillips JJ, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 31515627; PMCID: PMC6818961.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    46. Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM. Mol Cancer Ther. 2019 09; 18(9):1565-1576. McKinney A, Lindberg OR, Engler JR, Chen KY, Kumar A, Gong H, Lu KV, Simonds EF, Cloughesy TF, Liau LM, Prados M, Bollen AW, Berger MS, Shieh JTC, James CD, Nicolaides TP, Yong WH, Lai A, Hegi ME, Weiss WA, Phillips JJ. PMID: 31270152; PMCID: PMC6726545.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    47. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. 2019 09 05; 25(3):433-446.e7. Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, Cavalli FMG, Luu B, Moriarity BS, Ilkhanizadeh S, Chavez L, Yu C, Kurian KM, Magnaldo T, Sevenet N, Koch P, Pollard SM, Dirks P, Snyder MP, Largaespada DA, Cho YJ, Phillips JJ, Swartling FJ, Morrissy AS, Kool M, Pfister SM, Taylor MD, Smith A, Weiss WA. PMID: 31204176; PMCID: PMC6731167.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    48. High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Brain Pathol. 2020 01; 30(1):46-62. Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, Al-Hajri Z, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Schniederjan M, Cha S, Perry A, Solomon DA. PMID: 31104347; PMCID: PMC6859193.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    49. A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium. Int J Cancer. 2019 10 01; 145(7):1889-1901. Mueller S, Jain P, Liang WS, Kilburn L, Kline C, Gupta N, Panditharatna E, Magge SN, Zhang B, Zhu Y, Crawford JR, Banerjee A, Nazemi K, Packer RJ, Petritsch CK, Truffaux N, Roos A, Nasser S, Phillips JJ, Solomon D, Molinaro A, Waanders AJ, Byron SA, Berens ME, Kuhn J, Nazarian J, Prados M, Resnick AC. PMID: 30861105.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCTClinical Trials
    50. Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma. Acta Neuropathol. 2019 05; 137(5):851-854. Lee JC, Mazor T, Lao R, Wan E, Diallo AB, Hill NS, Thangaraj N, Wendelsdorf K, Samuel D, Kline CN, Banerjee A, Auguste K, Raffel C, Gupta N, Berger M, Raleigh DR, Shai A, Phillips JJ, Bollen AW, Tihan T, Perry A, Costello J, Solomon DA. PMID: 30877433; PMCID: PMC6483828.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    51. High density is a property of slow-cycling and treatment-resistant human glioblastoma cells. Exp Cell Res. 2019 05 01; 378(1):76-86. Sabelström H, Quigley DA, Fenster T, Foster DJ, Fuchshuber CAM, Saxena S, Yuan E, Li N, Paterno F, Phillips JJ, James CD, Norling B, Berger MS, Persson AI. PMID: 30844389.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    52. An oncolytic measles virus-sensitive Group 3 medulloblastoma model in immune-competent mice. Neuro Oncol. 2018 11 12; 20(12):1606-1615. Lal S, Carrera D, Phillips JJ, Weiss WA, Raffel C. PMID: 29912438; PMCID: PMC6231208.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    53. The genetic landscape of anaplastic pleomorphic xanthoastrocytoma. Brain Pathol. 2019 01; 29(1):85-96. Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, Tihan T, Bollen AW, Perry A, Shieh JTC, Solomon DA. PMID: 30051528; PMCID: PMC7837273.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    54. A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol. 2018 10; 20(10):1203-1214. Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. PMID: 30202050; PMCID: PMC6932748.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    55. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathol. 2019 01; 137(1):139-150. López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 30196423; PMCID: PMC6589431.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    56. Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma. J Neurooncol. 2018 Nov; 140(2):477-483. Taylor JW, Parikh M, Phillips JJ, James CD, Molinaro AM, Butowski NA, Clarke JL, Oberheim-Bush NA, Chang SM, Berger MS, Prados M. PMID: 30151703; PMCID: PMC6239922.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCTClinical Trials
    57. Relationship of In Vivo MR Parameters to Histopathological and Molecular Characteristics of Newly Diagnosed, Nonenhancing Lower-Grade Gliomas. Transl Oncol. 2018 Aug; 11(4):941-949. Luks TL, McKnight TR, Jalbert LE, Williams A, Neill E, Lobo KA, Persson AI, Perry A, Phillips JJ, Molinaro AM, Chang SM, Nelson SJ. PMID: 29883968; PMCID: PMC6041571.
      View in: PubMed   Mentions: 3  
    58. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. 2018 05 14; 33(5):874-889.e7. Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, Ghosh M, Tirosh I, Huillard E, Alvarez-Buylla A, Oldham MC, Persson AI, Weiss WA, Batchelor TT, Stemmer-Rachamimov A, Suvà ML, Phillips JJ, Aghi MK, Mehta S, Jain RK, Rowitch DH. PMID: 29681511; PMCID: PMC6211172.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    59. Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas. Neuro Oncol. 2018 04 09; 20(5):632-641. Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA, Costello JF. PMID: 29077933; PMCID: PMC5892142.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    60. Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner. Cancer Metab. 2018; 6:3. Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM. PMID: 29619216; PMCID: PMC5881177.
      View in: PubMed   Mentions: 19  
    61. Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation. Cell Rep. 2018 03 27; 22(13):3672-3683. Vasudevan HN, Braunstein SE, Phillips JJ, Pekmezci M, Tomlin BA, Wu A, Reis GF, Magill ST, Zhang J, Feng FY, Nicholaides T, Chang SM, Sneed PK, McDermott MW, Berger MS, Perry A, Raleigh DR. PMID: 29590631; PMCID: PMC8204688.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    62. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nat Commun. 2018 02 23; 9(1):810. Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA. PMID: 29476136; PMCID: PMC5824822.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    63. Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway. Acta Neuropathol. 2018 03; 135(3):485-488. Pekmezci M, Stevers M, Phillips JJ, Van Ziffle J, Bastian BC, Tsankova NM, Kleinschmidt-DeMasters BK, Rosenblum MK, Tihan T, Perry A, Solomon DA. PMID: 29428973; PMCID: PMC6067952.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    64. Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma. Mol Cancer Res. 2018 05; 16(5):777-790. Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley DA, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw JK, Burdick JA, Magnitsky S, Berger MS, Phillips JJ, Arosio D, Sun D, Weaver VM, Weiss WA, Persson AI. PMID: 29431617; PMCID: PMC5932284.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    65. 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas. Cancer Res. 2018 05 01; 78(9):2290-2304. Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM. PMID: 29358170; PMCID: PMC5932252.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    66. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 2018 01 08; 33(1):152. Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Gabriel Sauvé CE, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW. PMID: 29316430; PMCID: PMC5892424.
      View in: PubMed   Mentions: 78     Fields:    
    67. Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Mod Pathol. 2018 04; 31(4):660-673. Goode B, Joseph NM, Stevers M, Van Ziffle J, Onodera C, Talevich E, Grenert JP, Yeh I, Bastian BC, Phillips JJ, Garg K, Rabban JT, Zaloudek C, Solomon DA. PMID: 29148537; PMCID: PMC5906165.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    68. Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma. Clin Cancer Res. 2018 01 15; 24(2):295-305. Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, Maggiora GM, Peng S, Nasser S, Liang WS, Trent JM, Berens ME, Carpten JD, Craig DW, Prados MD. PMID: 29074604; PMCID: PMC7516926.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    69. Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression. Acta Neuropathol. 2017 Dec; 134(6):961-963. Lopez GY, Oberheim Bush NA, Phillips JJ, Bouffard JP, Moshel YA, Jaeckle K, Kleinschmidt-DeMasters BK, Rosenblum MK, Perry A, Solomon DA. PMID: 29063183; PMCID: PMC6078201.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    70. The driver landscape of sporadic chordoma. Nat Commun. 2017 10 12; 8(1):890. Tarpey PS, Behjati S, Young MD, Martincorena I, Alexandrov LB, Farndon SJ, Guzzo C, Hardy C, Latimer C, Butler AP, Teague JW, Shlien A, Futreal PA, Shah S, Bashashati A, Jamshidi F, Nielsen TO, Huntsman D, Baumhoer D, Brandner S, Wunder J, Dickson B, Cogswell P, Sommer J, Phillips JJ, Amary MF, Tirabosco R, Pillay N, Yip S, Stratton MR, Flanagan AM, Campbell PJ. PMID: 29026114; PMCID: PMC5638846.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    71. Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor. Transl Oncol. 2017 Dec; 10(6):895-903. Autry A, Phillips JJ, Maleschlijski S, Roy R, Molinaro AM, Chang SM, Cha S, Lupo JM, Nelson SJ. PMID: 28942218; PMCID: PMC5612804.
      View in: PubMed   Mentions: 6  
    72. Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10743-10748. Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, Cairncross JG, Perry A, Nelson SJ, Chang SM, Bollen AW, Molinaro AM, Bengtsson H, Olshen AB, Weiss S, Phillips JJ, Luchman HA, Costello JF. PMID: 28916733; PMCID: PMC5635900.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    73. Familial melanoma-astrocytoma syndrome: synchronous diffuse astrocytoma and pleomorphic xanthoastrocytoma in a patient with germline CDKN2A/B deletion and a significant family history. Clin Neuropathol. 2017 Sep/Oct; 36(5):213-221. Chan AK, Han SJ, Choy W, Beleford D, Aghi MK, Berger MS, Shieh JT, Bollen AW, Perry A, Phillips JJ, Butowski N, Solomon DA. PMID: 28699883; PMCID: PMC5628627.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    74. Heparan Sulfate Glycosaminoglycans in Glioblastoma Promote Tumor Invasion. Mol Cancer Res. 2017 11; 15(11):1623-1633. Tran VM, Wade A, McKinney A, Chen K, Lindberg OR, Engler JR, Persson AI, Phillips JJ. PMID: 28778876; PMCID: PMC6059807.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    75. Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas. Cancer. 2017 Dec 01; 123(23):4631-4639. Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D. PMID: 28759109; PMCID: PMC5693663.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    76. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 2017 07 10; 32(1):42-56.e6. Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Sauvé CG, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW. PMID: 28697342; PMCID: PMC5599156.
      View in: PubMed   Mentions: 549     Fields:    Translation:HumansCells
    77. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017 05 01; 19(5):699-709. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn WM, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. PMID: 28453743; PMCID: PMC5464451.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    78. Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma. Sci Rep. 2017 03 22; 7:44792. Jalbert LE, Elkhaled A, Phillips JJ, Neill E, Williams A, Crane JC, Olson MP, Molinaro AM, Berger MS, Kurhanewicz J, Ronen SM, Chang SM, Nelson SJ. PMID: 28327577; PMCID: PMC5361089.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    79. A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma. Cancer Cell. 2017 03 13; 31(3):424-435. Fan Q, Aksoy O, Wong RA, Ilkhanizadeh S, Novotny CJ, Gustafson WC, Truong AY, Cayanan G, Simonds EF, Haas-Kogan D, Phillips JJ, Nicolaides T, Okaniwa M, Shokat KM, Weiss WA. PMID: 28292440; PMCID: PMC5386178.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    80. Comparative analyses identify molecular signature of MRI-classified SVZ-associated glioblastoma. Cell Cycle. 2017 Apr 18; 16(8):765-775. Lin CA, Rhodes CT, Lin C, Phillips JJ, Berger MS. PMID: 28278055; PMCID: PMC5405724.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    81. Pediatric high-grade glioma: biologically and clinically in need of new thinking. Neuro Oncol. 2017 02 01; 19(2):153-161. Jones C, Karajannis MA, Jones DTW, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, Nicolaides T, Packer RJ, Persson AI, Phillips JJ, Simonds EF, Stafford JM, Tang Y, Pfister SM, Weiss WA. PMID: 27282398; PMCID: PMC5464243.
      View in: PubMed   Mentions: 122     Fields:    Translation:Humans
    82. Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide. Neuro Oncol. 2017 02 01; 19(2):242-251. Wahl M, Phillips JJ, Molinaro AM, Lin Y, Perry A, Haas-Kogan DA, Costello JF, Dayal M, Butowski N, Clarke JL, Prados M, Nelson S, Berger MS, Chang SM. PMID: 27571885; PMCID: PMC5464133.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCTClinical Trials
    83. Quantitative multi-modal MR imaging as a non-invasive prognostic tool for patients with recurrent low-grade glioma. J Neurooncol. 2017 03; 132(1):171-179. Neill E, Luks T, Dayal M, Phillips JJ, Perry A, Jalbert LE, Cha S, Molinaro A, Chang SM, Nelson SJ. PMID: 28124178; PMCID: PMC5373029.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    84. GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. Oncotarget. 2016 Nov 29; 7(48):79101-79116. Lindberg OR, McKinney A, Engler JR, Koshkakaryan G, Gong H, Robinson AE, Ewald AJ, Huillard E, David James C, Molinaro AM, Shieh JT, Phillips JJ. PMID: 27738329; PMCID: PMC5346701.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    85. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 2016 11 17; 167(5):1281-1295.e18. Hu B, Wang Q, Wang YA, Hua S, Sauvé CG, Ong D, Lan ZD, Chang Q, Ho YW, Monasterio MM, Lu X, Zhong Y, Zhang J, Deng P, Tan Z, Wang G, Liao WT, Corley LJ, Yan H, Zhang J, You Y, Liu N, Cai L, Finocchiaro G, Phillips JJ, Berger MS, Spring DJ, Hu J, Sulman EP, Fuller GN, Chin L, Verhaak RGW, DePinho RA. PMID: 27863244; PMCID: PMC5320931.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    86. Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model. Oncotarget. 2016 Nov 15; 7(46):75839-75853. Grossauer S, Koeck K, Murphy NE, Meyers ID, Daynac M, Truffaux N, Truong AY, Nicolaides TP, McMahon M, Berger MS, Phillips JJ, James CD, Petritsch CK. PMID: 27713119; PMCID: PMC5342782.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    87. Tissue mechanics promote IDH1-dependent HIF1α-tenascin C feedback to regulate glioblastoma aggression. Nat Cell Biol. 2016 Dec; 18(12):1336-1345. Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM. PMID: 27820599; PMCID: PMC5361403.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    88. Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia. Brain. 2016 12; 139(Pt 12):3202-3216. Vatsavayai SC, Yoon SJ, Gardner RC, Gendron TF, Vargas JN, Trujillo A, Pribadi M, Phillips JJ, Gaus SE, Hixson JD, Garcia PA, Rabinovici GD, Coppola G, Geschwind DH, Petrucelli L, Miller BL, Seeley WW. PMID: 27797809; PMCID: PMC5790143.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    89. Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process. Cancer Res. 2016 11 15; 76(22):6680-6689. Ohba S, Mukherjee J, Johannessen TC, Mancini A, Chow TT, Wood M, Jones L, Mazor T, Marshall RE, Viswanath P, Walsh KM, Perry A, Bell RJ, Phillips JJ, Costello JF, Ronen SM, Pieper RO. PMID: 27758882; PMCID: PMC5290072.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    90. Missense-depleted regions in population exomes implicate ras superfamily nucleotide-binding protein alteration in patients with brain malformation. NPJ Genom Med. 2016; 1. Ge X, Gong H, Dumas K, Litwin J, Phillips JJ, Waisfisz Q, Weiss MM, Hendriks Y, Stuurman KE, Nelson SF, Grody WW, Lee H, Kwok PY, Shieh JT. PMID: 28868155; PMCID: PMC5576364.
      View in: PubMed   Mentions: 20  
    91. Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation. Acta Neuropathol. 2016 11; 132(5):757-760. Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Jin LW, Bastian BC, Bollen AW, Perry A, Nicolaides T, Solomon DA, Shieh JT. PMID: 27624885; PMCID: PMC5074852.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    92. Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma. J Neurooncol. 2016 12; 130(3):543-552. Han SJ, Reis G, Kohanbash G, Shrivastav S, Magill ST, Molinaro AM, McDermott MW, Theodosopoulos PV, Aghi MK, Berger MS, Butowski NA, Barani I, Phillips JJ, Perry A, Okada H. PMID: 27624915; PMCID: PMC5560602.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    93. Safety Study: Intraventricular Injection of a Modified Oncolytic Measles Virus into Measles-Immune, hCD46-Transgenic, IFNαRko Mice. Hum Gene Ther Clin Dev. 2016 12; 27(4):145-151. Lal S, Peng KW, Steele MB, Jenks N, Ma H, Kohanbash G, Phillips JJ, Raffel C. PMID: 27604429.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    94. Protein Analysis of Glioblastoma Primary and Posttreatment Pairs Suggests a Mesenchymal Shift at Recurrence. J Neuropathol Exp Neurol. 2016 Oct; 75(10):925-935. Wood MD, Reis GF, Reuss DE, Phillips JJ. PMID: 27539476; PMCID: PMC6281078.
      View in: PubMed   Mentions: 16     Fields:    
    95. The Development of Reduced Diffusion Following Bevacizumab Therapy Identifies Regions of Recurrent Disease in Patients with High-grade Glioma. Acad Radiol. 2016 09; 23(9):1073-82. Barajas RF, Butowski NA, Phillips JJ, Aghi MK, Berger MS, Chang SM, Cha S. PMID: 27443507; PMCID: PMC5571825.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    96. PKM2 uses control of HuR localization to regulate p27 and cell cycle progression in human glioblastoma cells. Int J Cancer. 2016 Jul 01; 139(1):99-111. Mukherjee J, Ohba S, See WL, Phillips JJ, Molinaro AM, Pieper RO. PMID: 26874904; PMCID: PMC6615049.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    97. New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell. 2016 Feb 25; 164(5):1060-1072. Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DTW, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, Worst BC, Pajtler KW, Brabetz S, Johann PD, Sahm F, Reimand J, Mackay A, Carvalho DM, Remke M, Phillips JJ, Perry A, Cowdrey C, Drissi R, Fouladi M, Giangaspero F, Lastowska M, Grajkowska W, Scheurlen W, Pietsch T, Hagel C, Gojo J, Lötsch D, Berger W, Slavc I, Haberler C, Jouvet A, Holm S, Hofer S, Prinz M, Keohane C, Fried I, Mawrin C, Scheie D, Mobley BC, Schniederjan MJ, Santi M, Buccoliero AM, Dahiya S, Kramm CM, von Bueren AO, von Hoff K, Rutkowski S, Herold-Mende C, Frühwald MC, Milde T, Hasselblatt M, Wesseling P, Rößler J, Schüller U, Ebinger M, Schittenhelm J, Frank S, Grobholz R, Vajtai I, Hans V, Schneppenheim R, Zitterbart K, Collins VP, Aronica E, Varlet P, Puget S, Dufour C, Grill J, Figarella-Branger D, Wolter M, Schuhmann MU, Shalaby T, Grotzer M, van Meter T, Monoranu CM, Felsberg J, Reifenberger G, Snuderl M, Forrester LA, Koster J, Versteeg R, Volckmann R, van Sluis P, Wolf S, Mikkelsen T, Gajjar A, Aldape K, Moore AS, Taylor MD, Jones C, Jabado N, Karajannis MA, Eils R, Schlesner M, Lichter P, von Deimling A, Pfister SM, Ellison DW, Korshunov A, Kool M. PMID: 26919435; PMCID: PMC5139621.
      View in: PubMed   Mentions: 258     Fields:    Translation:HumansCells
    98. Magnetic resonance analysis of malignant transformation in recurrent glioma. Neuro Oncol. 2016 08; 18(8):1169-79. Jalbert LE, Neill E, Phillips JJ, Lupo JM, Olson MP, Molinaro AM, Berger MS, Chang SM, Nelson SJ. PMID: 26911151; PMCID: PMC4933480.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    99. MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. Mol Cancer Ther. 2016 05; 15(5):1113-22. Radoul M, Chaumeil MM, Eriksson P, Wang AS, Phillips JJ, Ronen SM. PMID: 26883274; PMCID: PMC4873419.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    100. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nat Genet. 2016 Mar; 48(3):273-82. Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P, Pages M, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S, Haas-Kogan DA, Phillips JJ, Santagata S, Stiles CD, Bradner JE, Jabado N, Goren A, Grill J, Ligon AH, Goumnerova L, Waanders AJ, Storm PB, Kieran MW, Ligon KL, Beroukhim R, Resnick AC. PMID: 26829751; PMCID: PMC4767685.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    101. Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations. Brain Pathol. 2016 09; 26(5):569-80. Solomon DA, Wood MD, Tihan T, Bollen AW, Gupta N, Phillips JJ, Perry A. PMID: 26517431; PMCID: PMC6055926.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    102. Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells. Cancer Res. 2015 Dec 15; 75(24):5355-66. Lerner RG, Grossauer S, Kadkhodaei B, Meyers I, Sidorov M, Koeck K, Hashizume R, Ozawa T, Phillips JJ, Berger MS, Nicolaides T, James CD, Petritsch CK. PMID: 26573800; PMCID: PMC4698003.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    103. A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. J Neurosurg. 2016 May; 124(5):1300-9. Lau D, Hervey-Jumper SL, Chang S, Molinaro AM, McDermott MW, Phillips JJ, Berger MS. PMID: 26544781.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCTClinical Trials
    104. DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors. Cancer Cell. 2015 Sep 14; 28(3):307-317. Mazor T, Pankov A, Johnson BE, Hong C, Hamilton EG, Bell RJA, Smirnov IV, Reis GF, Phillips JJ, Barnes MJ, Idbaih A, Alentorn A, Kloezeman JJ, Lamfers MLM, Bollen AW, Taylor BS, Molinaro AM, Olshen AB, Chang SM, Song JS, Costello JF. PMID: 26373278; PMCID: PMC4573399.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    105. IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism. Cancer Res. 2015 Aug 01; 75(15):2999-3009. Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM. PMID: 26045167; PMCID: PMC4526330.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    106. CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas. J Neuropathol Exp Neurol. 2015 May; 74(5):442-52. Reis GF, Pekmezci M, Hansen HM, Rice T, Marshall RE, Molinaro AM, Phillips JJ, Vogel H, Wiencke JK, Wrensch MR, Walsh KM, Perry A. PMID: 25853694; PMCID: PMC4397174.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    107. Toward precision medicine in glioblastoma: the promise and the challenges. Neuro Oncol. 2015 Aug; 17(8):1051-63. Prados MD, Byron SA, Tran NL, Phillips JJ, Molinaro AM, Ligon KL, Wen PY, Kuhn JG, Mellinghoff IK, de Groot JF, Colman H, Cloughesy TF, Chang SM, Ryken TC, Tembe WD, Kiefer JA, Berens ME, Craig DW, Carpten JD, Trent JM. PMID: 25934816; PMCID: PMC4490873.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    108. Proportional upregulation of CD97 isoforms in glioblastoma and glioblastoma-derived brain tumor initiating cells. PLoS One. 2015; 10(2):e0111532. Safaee M, Fakurnejad S, Bloch O, Clark AJ, Ivan ME, Sun MZ, Oh T, Phillips JJ, Parsa AT. PMID: 25714433; PMCID: PMC4340952.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    109. Metabolic reprogramming in mutant IDH1 glioma cells. PLoS One. 2015; 10(2):e0118781. Izquierdo-Garcia JL, Viswanath P, Eriksson P, Chaumeil MM, Pieper RO, Phillips JJ, Ronen SM. PMID: 25706986; PMCID: PMC4338038.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    110. Glycosylation alterations in lung and brain cancer. Adv Cancer Res. 2015; 126:305-44. Lemjabbar-Alaoui H, McKinney A, Yang YW, Tran VM, Phillips JJ. PMID: 25727152; PMCID: PMC6080207.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    111. Measuring sulfatase expression and invasion in glioblastoma. Methods Mol Biol. 2015; 1229:507-16. Wade A, Engler JR, Tran VM, Phillips JJ. PMID: 25325976; PMCID: PMC6059806.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    112. Practical molecular pathology and histopathology of embryonal tumors. Surg Pathol Clin. 2015 Mar; 8(1):73-88. Phillips J, Tihan T, Fuller G. PMID: 25783823.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    113. SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis. Clin Chim Acta. 2015 Feb 02; 440:72-8. Singer MS, Phillips JJ, Lemjabbar-Alaoui H, Wang YQ, Wu J, Goldman R, Rosen SD. PMID: 25444749; PMCID: PMC4305470.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    114. Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase. PLoS One. 2014; 9(9):e108289. Izquierdo-Garcia JL, Cai LM, Chaumeil MM, Eriksson P, Robinson AE, Pieper RO, Phillips JJ, Ronen SM. PMID: 25243911; PMCID: PMC4171511.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    115. Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas. J Neurooncol. 2015 Jan; 121(1):53-61. Ivan ME, Safaee M, Oh T, Clark AJ, Sun MZ, Kim J, Bloch O, Jahangiri A, Phillips JJ, Aghi MK, Parsa AT. PMID: 25200831; PMCID: PMC5553276.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    116. A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas. Acta Neuropathol. 2014 Nov; 128(5):743-53. Venneti S, Santi M, Felicella MM, Yarilin D, Phillips JJ, Sullivan LM, Martinez D, Perry A, Lewis PW, Thompson CB, Judkins AR. PMID: 25200322; PMCID: PMC4201755.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    117. A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma. Neuro Oncol. 2014 Jul; 16(7):984-90. Clarke JL, Molinaro AM, Phillips JJ, Butowski NA, Chang SM, Perry A, Costello JF, DeSilva AA, Rabbitt JE, Prados MD. PMID: 24637230; PMCID: PMC4057142.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    118. Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma. Cancer Res. 2014 Aug 15; 74(16):4247-57. Chaumeil MM, Larson PE, Woods SM, Cai L, Eriksson P, Robinson AE, Lupo JM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. PMID: 24876103; PMCID: PMC4134724.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    119. Characterization of metabolites in infiltrating gliomas using ex vivo ¹H high-resolution magic angle spinning spectroscopy. NMR Biomed. 2014 May; 27(5):578-93. Elkhaled A, Jalbert L, Constantin A, Yoshihara HA, Phillips JJ, Molinaro AM, Chang SM, Nelson SJ. PMID: 24596146; PMCID: PMC3983568.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    120. Cytogenetic prognostication within medulloblastoma subgroups. J Clin Oncol. 2014 Mar 20; 32(9):886-96. Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, Morrissy AS, Cavalli FM, Jones DT, Zitterbart K, Faria CC, Schüller U, Kren L, Kumabe T, Tominaga T, Shin Ra Y, Garami M, Hauser P, Chan JA, Robinson S, Bognár L, Klekner A, Saad AG, Liau LM, Albrecht S, Fontebasso A, Cinalli G, De Antonellis P, Zollo M, Cooper MK, Thompson RC, Bailey S, Lindsey JC, Di Rocco C, Massimi L, Michiels EM, Scherer SW, Phillips JJ, Gupta N, Fan X, Muraszko KM, Vibhakar R, Eberhart CG, Fouladi M, Lach B, Jung S, Wechsler-Reya RJ, Fèvre-Montange M, Jouvet A, Jabado N, Pollack IF, Weiss WA, Lee JY, Cho BK, Kim SK, Wang KC, Leonard JR, Rubin JB, de Torres C, Lavarino C, Mora J, Cho YJ, Tabori U, Olson JM, Gajjar A, Packer RJ, Rutkowski S, Pomeroy SL, French PJ, Kloosterhof NK, Kros JM, Van Meir EG, Clifford SC, Bourdeaut F, Delattre O, Doz FF, Hawkins CE, Malkin D, Grajkowska WA, Perek-Polnik M, Bouffet E, Rutka JT, Pfister SM, Taylor MD. PMID: 24493713; PMCID: PMC3948094.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    121. Matrix regulators in neural stem cell functions. Biochim Biophys Acta. 2014 Aug; 1840(8):2520-5. Wade A, McKinney A, Phillips JJ. PMID: 24447567; PMCID: PMC4074566.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    122. BRAF-V600E mutation in pediatric and adult glioblastoma. Neuro Oncol. 2014 Jan; 16(2):318-9. Dahiya S, Emnett RJ, Haydon DH, Leonard JR, Phillips JJ, Perry A, Gutmann DH. PMID: 24311634; PMCID: PMC3895374.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    123. Generation of a patient-derived chordoma xenograft and characterization of the phosphoproteome in a recurrent chordoma. J Neurosurg. 2014 Feb; 120(2):331-6. Davies JM, Robinson AE, Cowdrey C, Mummaneni PV, Ducker GS, Shokat KM, Bollen A, Hann B, Phillips JJ. PMID: 24286145; PMCID: PMC6059809.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    124. Mass spectral profiling of glycosaminoglycans from histological tissue surfaces. Anal Chem. 2013 Nov 19; 85(22):10984-91. Shao C, Shi X, Phillips JJ, Zaia J. PMID: 24099043; PMCID: PMC3872031.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    125. Frequent truncating mutations of STAG2 in bladder cancer. Nat Genet. 2013 Dec; 45(12):1428-30. Solomon DA, Kim JS, Bondaruk J, Shariat SF, Wang ZF, Elkahloun AG, Ozawa T, Gerard J, Zhuang D, Zhang S, Navai N, Siefker-Radtke A, Phillips JJ, Robinson BD, Rubin MA, Volkmer B, Hautmann R, Küfer R, Hogendoorn PC, Netto G, Theodorescu D, James CD, Czerniak B, Miettinen M, Waldman T. PMID: 24121789; PMCID: PMC3875130.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    126. Current management of choroid plexus carcinomas. Neurosurg Rev. 2014 Apr; 37(2):179-92; discussion 192. Sun MZ, Oh MC, Ivan ME, Kaur G, Safaee M, Kim JM, Phillips JJ, Auguste KI, Parsa AT. PMID: 24068529.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    127. Na⁺/K⁺-ATPase β2-subunit (AMOG) expression abrogates invasion of glioblastoma-derived brain tumor-initiating cells. Neuro Oncol. 2013 Nov; 15(11):1518-31. Sun MZ, Kim JM, Oh MC, Safaee M, Kaur G, Clark AJ, Bloch O, Ivan ME, Kaur R, Oh T, Fouse SD, Phillips JJ, Berger MS, Parsa AT. PMID: 23887941; PMCID: PMC3813412.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    128. The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas. Mod Pathol. 2013 Nov; 26(11):1425-32. Abedalthagafi M, Phillips JJ, Kim GE, Mueller S, Haas-Kogen DA, Marshall RE, Croul SE, Santi MR, Cheng J, Zhou S, Sullivan LM, Martinez-Lage M, Judkins AR, Perry A. PMID: 23765250; PMCID: PMC6054791.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    129. Tuberculoma of the central nervous system. J Clin Neurosci. 2013 Oct; 20(10):1333-41. DeLance AR, Safaee M, Oh MC, Clark AJ, Kaur G, Sun MZ, Bollen AW, Phillips JJ, Parsa AT. PMID: 23768968.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    130. Pilocytic astrocytomas of the optic nerve and their relation to pilocytic astrocytomas elsewhere in the central nervous system. Mod Pathol. 2013 Oct; 26(10):1279-87. Reis GF, Bloomer MM, Perry A, Phillips JJ, Grenert JP, Karnezis AN, Tihan T. PMID: 23702730.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    131. Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas. J Neuropathol Exp Neurol. 2013 Apr; 72(4):298-306. Venneti S, Felicella MM, Coyne T, Phillips JJ, Gorovets D, Huse JT, Kofler J, Lu C, Tihan T, Sullivan LM, Santi M, Judkins AR, Perry A, Thompson CB. PMID: 23481705; PMCID: PMC3615673.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    132. PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma. Brain Pathol. 2013 Sep; 23(5):565-73. Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, Martinez-Lage M, Robinson AE, Yong WH, Cloughesy T, Lai A, Phillips HS, Marshall R, Mueller S, Haas-Kogan DA, Molinaro AM, Perry A. PMID: 23438035; PMCID: PMC3715570.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    133. Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma. PLoS One. 2013; 8(2):e57610. Mukherjee J, Phillips JJ, Zheng S, Wiencke J, Ronen SM, Pieper RO. PMID: 23451252; PMCID: PMC3581484.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    134. Proteoglycans and their roles in brain cancer. FEBS J. 2013 May; 280(10):2399-417. Wade A, Robinson AE, Engler JR, Petritsch C, James CD, Phillips JJ. PMID: 23281850; PMCID: PMC3644380.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    135. Signals that regulate the oncogenic fate of neural stem cells and progenitors. Exp Neurol. 2014 Oct; 260:56-68. Swartling FJ, Bolin S, Phillips JJ, Persson AI. PMID: 23376224; PMCID: PMC3758390.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    136. Non-invasive in vivo assessment of IDH1 mutational status in glioma. Nat Commun. 2013; 4:2429. Chaumeil MM, Larson PE, Yoshihara HA, Danforth OM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. PMID: 24019001; PMCID: PMC3908661.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    137. Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM. J Magn Reson Imaging. 2013 Aug; 38(2):388-400. Essock-Burns E, Phillips JJ, Molinaro AM, Lupo JM, Cha S, Chang SM, Nelson SJ. PMID: 23281184; PMCID: PMC3711964.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    138. Epigenetic biomarkers of T-cells in human glioma. Epigenetics. 2012 Dec 01; 7(12):1391-402. Wiencke JK, Accomando WP, Zheng S, Patoka J, Dou X, Phillips JJ, Hsuang G, Christensen BC, Houseman EA, Koestler DC, Bracci P, Wiemels JL, Wiemels JL, Wrensch M, Nelson HH, Kelsey KT. PMID: 23108258; PMCID: PMC3528694.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    139. Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment. J Neurooncol. 2012 Dec; 110(3):305-13. Hashizume R, Smirnov I, Liu S, Phillips JJ, Hyer J, McKnight TR, Wendland M, Prados M, Banerjee A, Nicolaides T, Mueller S, James CD, Gupta N. PMID: 22983601.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    140. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS One. 2012; 7(8):e43339. Engler JR, Robinson AE, Smirnov I, Hodgson JG, Berger MS, Gupta N, James CD, Molinaro A, Phillips JJ. PMID: 22937035; PMCID: PMC3425586.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    141. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging. Magn Reson Med. 2013 Jul; 70(1):33-9. Park I, Hu S, Bok R, Ozawa T, Ito M, Mukherjee J, Phillips JJ, James CD, Pieper RO, Ronen SM, Vigneron DB, Nelson SJ. PMID: 22851374; PMCID: PMC3630274.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    142. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell. 2012 Jul 10; 22(1):21-35. Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G. PMID: 22789536; PMCID: PMC4068350.
      View in: PubMed   Mentions: 278     Fields:    Translation:HumansCells
    143. Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging. Neuro Oncol. 2012 Jul; 14(7):942-54. Barajas RF, Phillips JJ, Parvataneni R, Molinaro A, Essock-Burns E, Bourne G, Parsa AT, Aghi MK, McDermott MW, Berger MS, Cha S, Chang SM, Nelson SJ. PMID: 22711606; PMCID: PMC3379808.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    144. Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell. 2012 May 15; 21(5):601-613. Swartling FJ, Savov V, Persson AI, Chen J, Hackett CS, Northcott PA, Grimmer MR, Lau J, Chesler L, Perry A, Phillips JJ, Taylor MD, Weiss WA. PMID: 22624711; PMCID: PMC3360885.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    145. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8710-5. Huillard E, Hashizume R, Phillips JJ, Griveau A, Ihrie RA, Aoki Y, Nicolaides T, Perry A, Waldman T, McMahon M, Weiss WA, Petritsch C, James CD, Rowitch DH. PMID: 22586120; PMCID: PMC3365162.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    146. Novel therapeutic targets in the brain tumor microenvironment. Oncotarget. 2012 May; 3(5):568-75. Phillips JJ. PMID: 22643827; PMCID: PMC3388186.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    147. Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma. J Clin Invest. 2012 Mar; 122(3):911-22. Phillips JJ, Huillard E, Robinson AE, Ward A, Lum DH, Polley MY, Rosen SD, Rowitch DH, Werb Z. PMID: 22293178; PMCID: PMC3287216.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    148. Magnetic resonance of 2-hydroxyglutarate in IDH1-mutated low-grade gliomas. Sci Transl Med. 2012 Jan 11; 4(116):116ra5. Elkhaled A, Jalbert LE, Phillips JJ, Yoshihara HAI, Parvataneni R, Srinivasan R, Bourne G, Berger MS, Chang SM, Cha S, Nelson SJ. PMID: 22238333; PMCID: PMC3772177.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    149. Clinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association with the proneural subtype. J Neuropathol Exp Neurol. 2012 Jan; 71(1):83-9. Goldhoff P, Clarke J, Smirnov I, Berger MS, Prados MD, James CD, Perry A, Phillips JJ. PMID: 22157621; PMCID: PMC3246124.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    150. Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging. J Magn Reson Imaging. 2011 Jun; 33(6):1284-90. Park I, Bok R, Ozawa T, Phillips JJ, James CD, Vigneron DB, Ronen SM, Nelson SJ. PMID: 21590996; PMCID: PMC4983457.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    151. Choline metabolism, proliferation, and angiogenesis in nonenhancing grades 2 and 3 astrocytoma. J Magn Reson Imaging. 2011 Apr; 33(4):808-16. McKnight TR, Smith KJ, Chu PW, Chiu KS, Cloyd CP, Chang SM, Phillips JJ, Berger MS. PMID: 21448944; PMCID: PMC3076678.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    152. EMR-3: a potential mediator of invasive phenotypic variation in glioblastoma and novel therapeutic target. Neuroreport. 2010 Nov 17; 21(16):1018-22. Kane AJ, Sughrue ME, Rutkowski MJ, Phillips JJ, Parsa AT. PMID: 20827226; PMCID: PMC3064464.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    153. Ex vivo MR spectroscopic measure differentiates tumor from treatment effects in GBM. Neuro Oncol. 2010 Nov; 12(11):1152-61. Srinivasan R, Phillips JJ, Vandenberg SR, Polley MY, Bourne G, Au A, Pirzkall A, Cha S, Chang SM, Nelson SJ. PMID: 20647244; PMCID: PMC3098023.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    154. Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization. Arch Pathol Lab Med. 2010 Jul; 134(7):1063-9. Phillips JJ, Misra A, Feuerstein BG, Kunwar S, Tihan T. PMID: 20586639; PMCID: PMC3161118.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    155. Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15; 24(10):1059-72. Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L. PMID: 20478998; PMCID: PMC2867210.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    156. Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery. Cancer Res. 2010 Jun 01; 70(11):4520-7. Yoon DJ, Kwan BH, Chao FC, Nicolaides TP, Phillips JJ, Lam GY, Mason AB, Weiss WA, Kamei DT. PMID: 20460527; PMCID: PMC2893299.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    157. Limitations of diffusion-weighted imaging in distinguishing between a brain tumor and a central nervous system histoplasmoma. J Neurooncol. 2006 Sep; 79(2):217-8. Smith JS, Quiñones-Hinojosa A, Phillips JJ, Bollen AW, McDermott MW, Cha S. PMID: 16850113.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    158. Neurolisteriosis presenting as cervical myelitis in an immunocompetent patient. Neurology. 2006 Apr 11; 66(7):1122-3. Josephson SA, Pillai DR, Phillips JJ, Chou D. PMID: 16606936.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    159. Dandy-Walker malformation complex: correlation between ultrasonographic diagnosis and postmortem neuropathology. Obstet Gynecol. 2006 Mar; 107(3):685-93. Phillips JJ, Mahony BS, Siebert JR, Lalani T, Fligner CL, Kapur RP. PMID: 16507942.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    160. Contributions of the viral genetic background and a single amino acid substitution in an immunodominant CD8+ T-cell epitope to murine coronavirus neurovirulence. J Virol. 2005 Jul; 79(14):9108-18. MacNamara KC, Chua MM, Phillips JJ, Weiss SR. PMID: 15994805; PMCID: PMC1168726.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    161. Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system. Virology. 2003 Aug 01; 312(2):369-80. Tsai JC, de Groot L, Pinon JD, Iacono KT, Phillips JJ, Seo SH, Lavi E, Weiss SR. PMID: 12919742; PMCID: PMC7125853.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    162. Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system. Virology. 2002 Sep 15; 301(1):109-20. Phillips JJ, Chua MM, Rall GF, Weiss SR. PMID: 12359451; PMCID: PMC7131834.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    163. Multiple regions of the murine coronavirus spike glycoprotein influence neurovirulence. J Neurovirol. 2001 Oct; 7(5):421-31. Phillips JJ, Chua M, Seo SH, Weiss SR. PMID: 11582514; PMCID: PMC7095106.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    164. Mutation of the immunodominant CD8+ epitope in the MHV-4 spike protein. Adv Exp Med Biol. 2001; 494:121-5. Chua MM, Phillips JJ, Seo SH, Lavi E, Weiss SR. PMID: 11774455.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    165. MHV neuropathogenesis: the study of chimeric S genes and mutations in the hypervariable region. Adv Exp Med Biol. 2001; 494:115-9. Phillips JJ, Weiss SR. PMID: 11774454.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    166. Pathogenesis of chimeric MHV4/MHV-A59 recombinant viruses: the murine coronavirus spike protein is a major determinant of neurovirulence. J Virol. 1999 Sep; 73(9):7752-60. Phillips JJ, Chua MM, Lavi E, Weiss SR. PMID: 10438865; PMCID: PMC104302.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
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