Juan Qin, PhD

Title(s)Associate Researcher, Medicine
SchoolSchool of Medicine
Emailjuan.qin@ucsf.edu
Pronounsshe/her/hers
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    Collapse Biography 
    Collapse Education and Training
    Nankai University, Tianjin, CHNPhDCancer Biology
    University of California, Los Angeles, USAPostdoctoral ScholarCardiology
    Vanderbilt University Medical Center, Nashville, USAResearch FellowCardio-oncology
    Collapse Awards and Honors
    American Heart Association2024  - 2027 AHA's 2nd Century Early Faculty Independence Award
    University of California, San Francisco2024 UCSF Catalyst Award
    Keystone Symposia 2022Global Health Award
    Immunotherapy of Cancer2021Regular and Young Investigator Award

    Collapse Overview 
    Collapse Overview
    I am a Principal Investigator and Senior Data Scientist at the University of California, San Francisco, specializing in Cardio-Oncology, Immunology, and Bioinformatics. My research is dedicated to elucidating the mechanisms of cardiovascular diseases and cardiotoxic effects stemming from advanced cancer therapies. I apply machine learning to enhance drug discovery, disease diagnosis, and risk assessment, with the goal of developing safe and effective treatments for patients at high risk.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. PD-1–PD-L1 immunomodulatory pathway regulates cardiac regeneration. Nature Cardiovascular Research. 2024; 3(4):410-411. Juan Qin, Guo N. Huang, Javid Moslehi. View Publication.
    2. Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis. Nat Med. 2023 Dec; 29(12):3100-3110. Fenioux C, Abbar B, Boussouar S, Bretagne M, Power JR, Moslehi JJ, Gougis P, Amelin D, Dechartres A, Lehmann LH, Courand PY, Cautela J, Alexandre J, Procureur A, Rozes A, Leonard-Louis S, Qin J, International ICI-Myocarditis Registry, Cheynier R, Charmeteau-De Muylder B, Redheuil A, Tubach F, Cadranel J, Milon A, Ederhy S, Similowski T, Johnson DB, Pizzo I, Catalan T, Benveniste O, Hayek SS, Allenbach Y, Rosenzwajg M, Dolladille C, Salem JE. PMID: 37884625.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Machine Learning in Cardio-Oncology: New Insights from an Emerging Discipline. Reviews in Cardiovascular Medicine. 2023. Yi Zheng, Ziliang Chen, Shan Huang, Nan Zhang, Yueying Wang, Shenda Hong, Jeffrey Shi Kai Chan, Kang-Yin Chen, Yunlong Xia, Yuhui Zhang, Gregory Y.H. Lip, Juan Qin, Gary Tse, Tong Liu, . View Publication.
    4. Expansion of Pathogenic Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis. Circulation. 2024 01 02; 149(1):48-66. Ma P, Liu J, Qin J, Lai L, Heo GS, Luehmann H, Sultan D, Bredemeyer A, Bajapa G, Feng G, Jimenez J, He R, Parks A, Amrute J, Villanueva A, Liu Y, Lin CY, Mack M, Amancherla K, Moslehi J, Lavine KJ. PMID: 37746718.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    5. Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis. Cancer Discov. 2023 05 04; 13(5):1100-1115. Salem JE, Bretagne M, Abbar B, Leonard-Louis S, Ederhy S, Redheuil A, Boussouar S, Nguyen LS, Procureur A, Stein F, Fenioux C, Devos P, Gougis P, Dres M, Demoule A, Psimaras D, Lenglet T, Maisonobe T, De Chambrun MP, Hekimian G, Straus C, Gonzalez-Bermejo J, Klatzmann D, Rigolet A, Guillaume-Jugnot P, Champtiaux N, Benveniste O, Weiss N, Saheb S, Rouvier P, Plu I, Gandjbakhch E, Kerneis M, Hammoudi N, Zahr N, Llontop C, Morelot-Panzini C, Lehmann L, Qin J, Moslehi JJ, Rosenzwajg M, Similowski T, Allenbach Y. PMID: 36815259.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    6. Expansion of Disease Specific Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis. bioRxiv. 2023 Apr 29. Ma P, Liu J, Qin J, Lai L, Heo GS, Luehmann H, Sultan D, Bredemeyer A, Bajapa G, Feng G, Jimenez J, Parks A, Amrute J, Villanueva A, Liu Y, Lin CY, Mack M, Amancherla K, Moslehi J, Lavine KJ. PMID: 37162929; PMCID: PMC10168426.
      View in: PubMed   Mentions:
    7. Single-Nuclear RNA Sequencing of Endomyocardial Biopsies Identifies Persistence of Donor-Recipient Chimerism With Distinct Signatures in Severe Cardiac Allograft Vasculopathy. Circ Heart Fail. 2023 01; 16(1):e010119. Amancherla K, Qin J, Hulke ML, Pfeiffer RD, Agrawal V, Sheng Q, Xu Y, Schlendorf KH, Lindenfeld J, Shah RV, Freedman JE, Tucker NR, Moslehi J. PMID: 36524467; PMCID: PMC9852032.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. T cells specific for α-myosin drive immunotherapy-related myocarditis. Nature. 2022 11; 611(7937):818-826. Axelrod ML, Meijers WC, Screever EM, Qin J, Carroll MG, Sun X, Tannous E, Zhang Y, Sugiura A, Taylor BC, Hanna A, Zhang S, Amancherla K, Tai W, Wright JJ, Wei SC, Opalenik SR, Toren AL, Rathmell JC, Ferrell PB, Phillips EJ, Mallal S, Johnson DB, Allison JP, Moslehi JJ, Balko JM. PMID: 36385524; PMCID: PMC9930174.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    9. Hormonal therapies up-regulate MANF and overcome female susceptibility to immune checkpoint inhibitor myocarditis. Sci Transl Med. 2022 11 02; 14(669):eabo1981. Zhang Y, Sun C, Li Y, Qin J, Amancherla K, Jing Y, Hu Q, Liang K, Zhang Z, Ye Y, Huang LA, Nguyen TK, Egranov SD, Zhao Z, Wu A, Xi Y, Yao J, Hung MC, Calin GA, Cheng J, Lim B, Lehmann LH, Salem JE, Johnson DB, Curran MA, Yu D, Han L, Darabi R, Yang L, Moslehi JJ, Lin C. PMID: 36322628; PMCID: PMC9809130.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    10. Targeting the HDAC6-Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity. Adv Sci (Weinh). 2022 07; 9(21):e2105365. Ran J, Zhang Y, Zhang S, Li H, Zhang L, Li Q, Qin J, Li D, Sun L, Xie S, Zhang X, Liu L, Liu M, Zhou J. PMID: 35619548; PMCID: PMC9313505.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. RNA-Sequencing Reveals a Distinct Transcriptomic Signature for Giant Cell Myocarditis and Identifies Novel Druggable Targets. Circ Res. 2021 07 23; 129(3):451-453. Amancherla K, Qin J, Wang Y, Axelrod ML, Balko JM, Schlendorf KH, Hoffman RD, Xu Y, Lindenfeld J, Moslehi J. PMID: 34126013; PMCID: PMC8380472.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. Deregulated ALG-2/HEBP2 axis alters microtubule dynamics and mitotic spindle behavior to stimulate cancer development. J Cell Physiol. 2017 Nov; 232(11):3067-3076. Qin J, Yang Y, Gao S, Liu Y, Yu F, Zhou Y, Lyu R, Liu M, Liu X, Li D, Zhou J. PMID: 28004381.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    13. Apoptosis-linked gene 2 promotes breast cancer growth and metastasis by regulating the cytoskeleton. Oncotarget. 2017 Jan 10; 8(2):2745-2757. Qin J, Li D, Zhou Y, Xie S, Du X, Hao Z, Liu R, Liu X, Liu M, Zhou J. PMID: 27926525; PMCID: PMC5356838.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    14. Discovery of Centrosomal Protein 70 as an Important Player in the Development and Progression of Breast Cancer. Am J Pathol. 2017 Mar; 187(3):679-688. Shi X, Li D, Wang Y, Liu S, Qin J, Wang J, Ran J, Zhang Y, Huang Q, Liu X, Zhou J, Liu M. PMID: 28063737.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    15. Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice. Oncotarget. 2016 May 10; 7(19):27527-37. Ran J, Yu F, Qin J, Zhang Y, Yang Y, Li D, Zhou J, Liu M. PMID: 27028867; PMCID: PMC5053669.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    16. Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization. Sci Rep. 2016 Feb 19; 6:21263. Xie S, Qin J, Liu S, Zhang Y, Wang J, Shi X, Li D, Zhou J, Liu M. PMID: 26893288; PMCID: PMC4759539.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    17. Identification of novel microtubule-binding proteins by taxol-mediated microtubule stabilization and mass spectrometry analysis. Thorac Cancer. 2015 Sep; 6(5):649-54. He X, Liu Z, He Q, Qin J, Liu N, Zhang L, Li D, Zhou J, Shui W, Liu M. PMID: 26445615; PMCID: PMC4567012.
      View in: PubMed   Mentions: 9     Fields:    
    18. Lonafarnib is a potential inhibitor for neovascularization. PLoS One. 2015; 10(4):e0122830. Sun L, Xie S, Peng G, Wang J, Li Y, Qin J, Zhong D. PMID: 25853815; PMCID: PMC4390146.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    19. Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region. Cell Biosci. 2014; 4(1):61. Zhang L, Qin J, Li Y, Wang J, He Q, Zhou J, Liu M, Li D. PMID: 25328666; PMCID: PMC4201738.
      View in: PubMed   Mentions: 10  
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