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[AI-based discovery of broadly neutralizing antibodies against HIV-1]. Med Sci (Paris). 2024 Nov; 40(11):819-821.
Foglierini M, Perez L. PMID: 39656977.
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PubMed Mentions: Fields:
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RAIN: machine learning-based identification for HIV-1 bNAbs. Nat Commun. 2024 Jun 24; 15(1):5339.
Foglierini M, Nortier P, Schelling R, Winiger RR, Jacquet P, O'Dell S, Demurtas D, Mpina M, Lweno O, Muller YD, Petrovas C, Daubenberger C, Perreau M, Doria-Rose NA, Gottardo R, Perez L. PMID: 38914562; PMCID: PMC11196741.
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2 Fields:
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HumansCells
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Non-uptake of COVID-19 vaccines and reasons for non-uptake among healthcare workers in Uganda: a cross-sectional study. BMC Health Serv Res. 2024 May 25; 24(1):663.
Kyakuwa N, Abaasa A, Mpooya S, Kalutte H, Atuhairwe C, Perez L, Kikaire B. PMID: 38796411; PMCID: PMC11128104.
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HumansCells
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Therapeutic antibodies and alternative formats against SARS-CoV-2. Antiviral Res. 2024 03; 223:105820.
Winiger RR, Perez L. PMID: 38307147.
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4 Fields:
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HumansCellsPHPublic Health
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Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys. J Infect. 2023 12; 87(6):524-537.
Fenwick C, Turelli P, Duhoo Y, Lau K, Herate C, Marlin R, Lamrayah M, Campos J, Esteves-Leuenberger L, Farina A, Raclot C, Genet V, Fiscalini F, Cesborn J, Perez L, Dereuddre-Bosquet N, Contreras V, Lheureux K, Relouzat F, Abdelnabi R, Leyssen P, Lévy Y, Pojer F, Le Grand R, Trono D, Pantaleo G. PMID: 37852477.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses. Immunity. 2023 Oct 10; 56(10):2425-2441.e14.
Ols S, Lenart K, Arcoverde Cerveira R, Miranda MC, Brunette N, Kochmann J, Corcoran M, Skotheim R, Philomin A, Cagigi A, Fiala B, Wrenn S, Marcandalli J, Hellgren F, Thompson EA, Lin A, Gegenfurtner F, Kumar A, Chen M, Phad GE, Graham BS, Perez L, Borst AJ, Karlsson Hedestam GB, Ruckwardt TJ, King NP, Loré K. PMID: 37689061.
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PubMed Mentions:
28 Fields:
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Intradermal skin test with mRNA vaccines as a surrogate marker of T cell immunity in immunocompromised patients. J Infect. 2023 08; 87(2):111-119.
Fallet B, Foglierini M, Porret R, Alcaraz-Serna A, Sauvage C, Jenelten R, Caplanusi T, Gilliet M, Perez L, Fenwick C, Genolet R, Harari A, Bobisse S, Gottardo R, Pantaleo G, Muller YD. PMID: 37321353; PMCID: PMC10264165.
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HumansCellsPHPublic Health
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Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys. Nat Microbiol. 2022 09; 7(9):1376-1389.
Fenwick C, Turelli P, Ni D, Perez L, Lau K, Herate C, Marlin R, Lana E, Pellaton C, Raclot C, Esteves-Leuenberger L, Campos J, Farina A, Fiscalini F, Dereuddre-Bosquet N, Relouzat F, Abdelnabi R, Foo CS, Neyts J, Leyssen P, Lévy Y, Pojer F, Stahlberg H, LeGrand R, Trono D, Pantaleo G. PMID: 35879526; PMCID: PMC9418005.
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PubMed Mentions:
21 Fields:
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HumansAnimalsCells
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Antibodies to combat viral infections: development strategies and progress. Nat Rev Drug Discov. 2022 09; 21(9):676-696.
Pantaleo G, Correia B, Fenwick C, Joo VS, Perez L. PMID: 35725925; PMCID: PMC9207876.
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115 Fields:
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HumansCellsPHPublic Health
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Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv. 2022 Mar 11; 8(10):eabm2536.
Kschonsak M, Johnson MC, Schelling R, Green EM, Rougé L, Ho H, Patel N, Kilic C, Kraft E, Arthur CP, Rohou AL, Comps-Agrar L, Martinez-Martin N, Perez L, Payandeh J, Ciferri C. PMID: 35275719; PMCID: PMC8916737.
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12 Fields:
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Characterizing cytomegalovirus infection one cell at a time. Nat Microbiol. 2021 12; 6(12):1477-1478.
Perez L. PMID: 34697463.
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HumansCells
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A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell Rep. 2021 10 12; 37(2):109814.
Fenwick C, Turelli P, Perez L, Pellaton C, Esteves-Leuenberger L, Farina A, Campos J, Lana E, Fiscalini F, Raclot C, Pojer F, Lau K, Demurtas D, Descatoire M, Joo VS, Foglierini M, Noto A, Abdelnabi R, Foo CS, Vangeel L, Neyts J, Du W, Bosch BJ, Veldman G, Leyssen P, Thiel V, LeGrand R, Lévy Y, Trono D, Pantaleo G. PMID: 34599871; PMCID: PMC8452523.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response. Immunity. 2021 09 14; 54(9):2005-2023.e10.
Glaros V, Rauschmeier R, Artemov AV, Reinhardt A, Ols S, Emmanouilidi A, Gustafsson C, You Y, Mirabello C, Björklund ÅK, Perez L, King NP, Månsson R, Angeletti D, Loré K, Adameyko I, Busslinger M, Kreslavsky T. PMID: 34525339; PMCID: PMC7612941.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28. Front Immunol. 2021; 12:639818.
Muller YD, Nguyen DP, Ferreira LMR, Ho P, Raffin C, Valencia RVB, Congrave-Wilson Z, Roth TL, Eyquem J, Van Gool F, Marson A, Perez L, Wells JA, Bluestone JA, Tang Q. PMID: 33833759; PMCID: PMC8021955.
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PubMed Mentions:
64 Fields:
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HumansCells
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Chimeric antigen receptor T-cell therapy for HIV cure. Curr Opin HIV AIDS. 2021 03 01; 16(2):88-97.
Alfageme-Abello O, Porret R, Perreau M, Perez L, Muller YD. PMID: 33560017.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity. PLoS Pathog. 2020 12; 16(12):e1009169.
Perotti M, Marcandalli J, Demurtas D, Sallusto F, Perez L. PMID: 33370407; PMCID: PMC7794029.
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PubMed Mentions:
14 Fields:
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HumansAnimalsCells
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β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4. Front Immunol. 2020; 11:550824.
D'Agostino G, Artinger M, Locati M, Perez L, Legler DF, Bianchi ME, Rüegg C, Thelen M, Marchese A, Rocchi MBL, Cecchinato V, Uguccioni M. PMID: 33072091; PMCID: PMC7533569.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus. Cell. 2019 03 07; 176(6):1420-1431.e17.
Marcandalli J, Fiala B, Ols S, Perotti M, de van der Schueren W, Snijder J, Hodge E, Benhaim M, Ravichandran R, Carter L, Sheffler W, Brunner L, Lawrenz M, Dubois P, Lanzavecchia A, Sallusto F, Lee KK, Veesler D, Correnti CE, Stewart LJ, Baker D, Loré K, Perez L, King NP. PMID: 30849373; PMCID: PMC6424820.
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An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor. Cell. 2018 08 23; 174(5):1158-1171.e19.
Martinez-Martin N, Marcandalli J, Huang CS, Arthur CP, Perotti M, Foglierini M, Ho H, Dosey AM, Shriver S, Payandeh J, Leitner A, Lanzavecchia A, Perez L, Ciferri C. PMID: 30057110.
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PubMed Mentions:
140 Fields:
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HumansCells
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A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nat Med. 2018 05; 24(4):401-407.
Tan J, Sack BK, Oyen D, Zenklusen I, Piccoli L, Barbieri S, Foglierini M, Fregni CS, Marcandalli J, Jongo S, Abdulla S, Perez L, Corradin G, Varani L, Sallusto F, Sim BKL, Hoffman SL, Kappe SHI, Daubenberger C, Wilson IA, Lanzavecchia A. PMID: 29554084; PMCID: PMC5893353.
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PubMed Mentions:
127 Fields:
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HumansAnimals
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Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells. Proc Natl Acad Sci U S A. 2017 06 20; 114(25):E4924-E4933.
Genini D, Brambilla L, Laurini E, Merulla J, Civenni G, Pandit S, D'Antuono R, Perez L, Levy DE, Pricl S, Carbone GM, Catapano CV. PMID: 28584133; PMCID: PMC5488915.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells